Component: Angelica sinensis 当归


Description of the Component

Component ID
TCMH421
Latin Name
Angelica sinensis
English Name
Chinese angelica
Chinese Pinyin Name
Dang Gui
中文名
当归
TCM Properties
Warm,Pungent,Sweet
TCM Meridians
Spleen,Liver,Heart
Therapeutic Class English
For tonifying weakness
Therapeutic Class Chinese
补虚
Functions
enrich blood, activate blood circulation, regulate menstruation, relieve pain, and relax bowels
Toxicity
NA
Geo-authentic habitats (道地产区)
Gansu Province
Reference
Chinese Pharmacopoeia (2015)
Barcode ID
ITSAF173-14
Barcode Source
BOLDSYSTEMS

TCM Prescriptions with the Component

Prescription ID Prescription English Name Prescription Chinese Name

Targeted Human Proteins by the Ingredient of Component

Target ID Gene Symbol Target Name Target Class Uniprot ID
TCMT1 EHMT2 Histone-lysine N-methyltransferase, H3 lysine-9 specific 3 Transferase Q96KQ7
TCMT100 TTR Transthyretin Unclassified P02766
TCMT101 PTPN1 Protein-tyrosine phosphatase 1B Hydrolase P18031
TCMT11 HIF1A Hypoxia-inducible factor 1 alpha Transcription factor Q16665
TCMT112 ADORA3 Adenosine A3 receptor GPCR P0DMS8
TCMT117 OPRK1 Kappa opioid receptor GPCR P41145
TCMT125 GBA Beta-glucocerebrosidase Hydrolase P04062
TCMT126 TERT Telomerase reverse transcriptase Transferase O14746
TCMT13 APEX1 DNA-(apurinic or apyrimidinic site) lyase Lyase P27695
TCMT130 ALOX5 Arachidonate 5-lipoxygenase Oxidoreductase P09917
TCMT131 ACHE Acetylcholinesterase Hydrolase P22303
TCMT133 CA1 Carbonic anhydrase I Lyase P00915
TCMT134 CA2 Carbonic anhydrase II Lyase P00918
TCMT135 CA14 Carbonic anhydrase XIV Lyase Q9ULX7
TCMT136 CA12 Carbonic anhydrase XII Lyase O43570
TCMT137 CA9 Carbonic anhydrase IX Lyase Q16790
TCMT138 CA7 Carbonic anhydrase VII Lyase P43166
TCMT139 CA6 Carbonic anhydrase VI Lyase P23280
TCMT140 CA5B Carbonic anhydrase VB Lyase Q9Y2D0
TCMT141 CA5A Carbonic anhydrase VA Lyase P35218
TCMT142 CA4 Carbonic anhydrase IV Lyase P22748
TCMT143 CA3 Carbonic anhydrase III Lyase P07451
TCMT150 RORC Nuclear receptor ROR-gamma Nuclear receptor P51449
TCMT151 PRKCA Protein kinase C alpha Kinase P17252
TCMT156 CYP19A1 Cytochrome P450 19A1 Oxidoreductase P11511
TCMT159 TYR Tyrosinase Oxidoreductase P14679
TCMT160 HTR7 Serotonin 7 (5-HT7) receptor GPCR P34969
TCMT161 HCAR2 Hydroxycarboxylic acid receptor 2 GPCR Q8TDS4
TCMT162 UGT1A1 UDP-glucuronosyltransferase 1-1 Transferase P22309
TCMT164 PTGS1 Cyclooxygenase-1 Oxidoreductase P23219
TCMT166 AKR1C2 Aldo-keto reductase family 1 member C2 Oxidoreductase P52895
TCMT167 AKR1C3 Aldo-keto-reductase family 1 member C3 Oxidoreductase P42330
TCMT168 AKR1C4 Aldo-keto reductase family 1 member C4 Oxidoreductase P17516
TCMT17 POLB DNA polymerase beta Transferase P06746
TCMT176 SOAT1 Acyl coenzyme A:cholesterol acyltransferase 1 Transferase P35610
TCMT18 GAA Lysosomal alpha-glucosidase Hydrolase P10253
TCMT186 MAOB Monoamine oxidase B Oxidoreductase P27338
TCMT189 DUSP3 Dual specificity protein phosphatase 3 Hydrolase P51452
TCMT193 RELA Nuclear factor NF-kappa-B p65 subunit Transcription factor Q04206
TCMT195 MAP2K1 Dual specificity mitogen-activated protein kinase kinase 1 Kinase Q02750
TCMT2 MAPT Microtubule-associated protein tau Unclassified P10636
TCMT206 CYP2A6 Cytochrome P450 2A6 Oxidoreductase P11509
TCMT207 BACE1 Beta-secretase 1 Protease P56817
TCMT208 MAOA Monoamine oxidase A Oxidoreductase P21397
TCMT213 SLC22A1 Solute carrier family 22 member 1 Transporter O15245
TCMT219 CYP1A2 Cytochrome P450 1A2 Oxidoreductase P05177
TCMT223 AKR1B1 Aldose reductase Oxidoreductase P15121
TCMT225 CA13 Carbonic anhydrase XIII Lyase Q8N1Q1
TCMT232 ABCB1 P-glycoprotein 1 Transporter P08183
TCMT248 CXCL8 Interleukin-8 Unclassified P10145
TCMT265 GSK3B Glycogen synthase kinase-3 beta Kinase P49841
TCMT267 GABRR1 GABA receptor rho-1 subunit Ion channel P24046
TCMT268 CYP2A13 Cytochrome P450 2A13 Oxidoreductase Q16696
TCMT27 DRD1 Dopamine D1 receptor GPCR P21728
TCMT276 SLCO2B1 Solute carrier organic anion transporter family member 2B1 Transporter O94956
TCMT277 SLCO1B3 Solute carrier organic anion transporter family member 1B3 Transporter Q9NPD5
TCMT278 SLCO1B1 Solute carrier organic anion transporter family member 1B1 Transporter Q9Y6L6
TCMT280 AKR1B10 Aldo-keto reductase family 1 member B10 Oxidoreductase O60218
TCMT281 DPP4 Dipeptidyl peptidase IV Unclassified P27487
TCMT295 MMP1 Matrix metalloproteinase-1 Hydrolase P03956
TCMT296 ADORA1 Adenosine A1 receptor GPCR P30542
TCMT297 FABP4 Fatty acid binding protein adipocyte Unclassified P15090
TCMT298 FABP3 Fatty acid binding protein muscle Hydrolase P05413
TCMT3 ALOX15 Arachidonate 15-lipoxygenase Oxidoreductase P16050
TCMT30 PTGS2 Cyclooxygenase-2 Oxidoreductase P35354
TCMT306 MMP2 Matrix metalloproteinase-2 Hydrolase P08253
TCMT307 KCNH2 HERG Ion channel Q12809
TCMT31 CYP2C19 Cytochrome P450 2C19 Oxidoreductase P33261
TCMT311 SLC47A1 Multidrug and toxin extrusion protein 1 Transporter Q96FL8
TCMT320 MMP3 Matrix metalloproteinase 3 Hydrolase P08254
TCMT321 MMP9 Matrix metalloproteinase 9 Hydrolase P14780
TCMT327 TRPV1 Vanilloid receptor Ion channel Q8NER1
TCMT33 CYP3A4 Cytochrome P450 3A4 Oxidoreductase P08684
TCMT336 IDO1 Indoleamine 2,3-dioxygenase Oxidoreductase P14902
TCMT34 CYP2D6 Cytochrome P450 2D6 Oxidoreductase P10635
TCMT340 GLRA1 Glycine receptor subunit alpha-1 Ion channel P23415
TCMT341 NR1I2 Pregnane X receptor Nuclear receptor O75469
TCMT401 MET Hepatocyte growth factor receptor Kinase P08581
TCMT41 IDH1 Isocitrate dehydrogenase [NADP] cytoplasmic Oxidoreductase O75874
TCMT42 KMT2A Histone-lysine N-methyltransferase MLL Transferase Q03164
TCMT423 EGFR Epidermal growth factor receptor erbB1 Kinase P00533
TCMT45 APP Beta amyloid A4 protein Unclassified P05067
TCMT46 F3 Coagulation factor III Unclassified P13726
TCMT466 MAPK9 c-Jun N-terminal kinase 2 Kinase P45984
TCMT479 AKT1 Serine/threonine-protein kinase AKT Kinase P31749
TCMT507 MAPK14 MAP kinase p38 alpha Kinase Q16539
TCMT555 HDAC6 Histone deacetylase 6 Hydrolase Q9UBN7
TCMT556 HDAC2 Histone deacetylase 2 Hydrolase Q92769
TCMT557 HDAC1 Histone deacetylase 1 Hydrolase Q13547
TCMT571 ADORA2B Adenosine A2b receptor GPCR P29275
TCMT588 DAO D-amino-acid oxidase Oxidoreductase P14920
TCMT592 XDH Xanthine dehydrogenase Oxidoreductase P47989
TCMT597 SLC28A3 Solute carrier family 28 member 3 Transporter Q9HAS3
TCMT6 NFKB1 Nuclear factor NF-kappa-B p105 subunit Transcription factor P19838
TCMT605 EDNRA Endothelin receptor ET-A GPCR P25101
TCMT609 CTSL Cathepsin L Unclassified P07711
TCMT614 EGLN1 Egl nine homolog 1 Oxidoreductase Q9GZT9
TCMT620 HSPA8 Heat shock cognate 71 kDa protein Unclassified P11142
TCMT624 HSP90AB1 Heat shock protein HSP 90-beta Unclassified P08238
TCMT63 PPARA Peroxisome proliferator-activated receptor alpha Nuclear receptor Q07869
TCMT632 PNP Purine nucleoside phosphorylase Transferase P00491
TCMT64 PPARD Peroxisome proliferator-activated receptor delta Nuclear receptor Q03181
TCMT67 PPARG Peroxisome proliferator-activated receptor gamma Nuclear receptor P37231
TCMT69 THRB Thyroid hormone receptor beta-1 Nuclear receptor P10828
TCMT690 HDAC3 Histone deacetylase 3 Hydrolase O15379
TCMT691 HDAC8 Histone deacetylase 8 Hydrolase Q9BY41
TCMT704 ERBB2 Receptor protein-tyrosine kinase erbB-2 Kinase P04626
TCMT707 ADORA2A Adenosine A2a receptor GPCR P29274
TCMT709 SLC28A2 Sodium/nucleoside cotransporter 2 Transporter O43868
TCMT710 SLC28A1 Sodium/nucleoside cotransporter 1 Transporter O00337
TCMT714 ODC1 Ornithine decarboxylase Lyase P11926
TCMT8 KDM4E Lysine-specific demethylase 4D-like Oxidoreductase B2RXH2
TCMT80 MAPK1 MAP kinase ERK2 Kinase P28482
TCMT808 FABP5 Fatty acid binding protein epidermal Unclassified Q01469
TCMT809 FABP2 Fatty acid binding protein intestinal Unclassified P12104
TCMT81 ALOX12 Arachidonate 12-lipoxygenase Oxidoreductase P18054
TCMT810 TLR2 Toll-like receptor 2 Unclassified O60603
TCMT82 ESR1 Estrogen receptor alpha Nuclear receptor P03372
TCMT87 CYP2C9 Cytochrome P450 2C9 Oxidoreductase P11712
TCMT95 MPG DNA-3-methyladenine glycosylase Hydrolase P29372
TCMT96 LDHA L-lactate dehydrogenase A chain Oxidoreductase P00338


Targeted Pathogenic Microbes by the Ingredient of Component

Target ID Target Name
TCMT1108 Integrase
TCMT1112 Quinolone resistance protein norA
TCMT1190 Plasmodium falciparum (isolate FcB1 / Columbia)
TCMT1218 Staphylococcus aureus
TCMT1223 Staphylococcus epidermidis
TCMT1226 Klebsiella pneumoniae
TCMT1232 Pseudomonas aeruginosa
TCMT1245 Phytophthora cactorum
TCMT1246 Escherichia coli
TCMT1251 Candida albicans
TCMT1253 Penicillium chrysogenum
TCMT1294 Human parainfluenza virus 3
TCMT1346 Helicobacter pylori
TCMT1349 Helicobacter pylori SS1
TCMT1361 Neisseria meningitidis
TCMT1382 Plasmodium falciparum (isolate K1 / Thailand)
TCMT1408 Colletotrichum gloeosporioides
TCMT1438 Plasmodium falciparum
TCMT1439 Mycobacterium smegmatis
TCMT1442 Leishmania donovani
TCMT1444 Fusarium oxysporum
TCMT1448 Enterobacter aerogenes
TCMT1454 Bacillus subtilis
TCMT1455 Mycobacterium tuberculosis H37Rv
TCMT1458 Filobasidiella neoformans
TCMT1462 Streptococcus mutans
TCMT1463 Mycobacterium tuberculosis
TCMT1465 Entamoeba histolytica

Ingredient Structrues

Ingredient ID: TCMC999
Formula: C10H20O2

Ingredient ID: TCMC985
Formula: C3H7NO2

Ingredient ID: TCMC960
Formula: C10H12O

Ingredient ID: TCMC936
Formula: C14H14O4

Ingredient ID: TCMC924
Formula: C10H20O

Ingredient ID: TCMC923
Formula: C6H8O7

Ingredient ID: TCMC897
Formula: C16H18O9

Ingredient ID: TCMC887
Formula: C16H34O

Ingredient ID: TCMC886
Formula: C18H38O

Ingredient ID: TCMC872
Formula: C10H14O

Ingredient ID: TCMC855
Formula: C16H12O5

Ingredient ID: TCMC847
Formula: C9H8O4

Ingredient ID: TCMC844
Formula: C4H10O

Ingredient ID: TCMC837
Formula: C4H8O2

Ingredient ID: TCMC834
Formula: C4H8O

Ingredient ID: TCMC817
Formula: C16H22O4

Ingredient ID: TCMC801
Formula: C29H50O

Ingredient ID: TCMC787
Formula: C12H8O4

Ingredient ID: TCMC753
Formula: C9H16O4

Ingredient ID: TCMC7375
Formula: C24H28O4

Ingredient ID: TCMC7359
Formula: C10H12O2

Ingredient ID: TCMC7247
Formula: C15H24

Ingredient ID: TCMC697
Formula: C11H6O3

Ingredient ID: TCMC6969
Formula: C15H24

Ingredient ID: TCMC69
Formula: C4H6O5

Ingredient ID: TCMC671
Formula: C10H16

Ingredient ID: TCMC65
Formula: C14H14O4

Ingredient ID: TCMC648
Formula: C2H6O

Ingredient ID: TCMC6345
Formula: C15H24

Ingredient ID: TCMC632
Formula: C10H13N5O4

Ingredient ID: TCMC631
Formula: C5H5N5

Ingredient ID: TCMC62
Formula: C16H24O4

Ingredient ID: TCMC610
Formula: C6H12O2

Ingredient ID: TCMC60
Formula: C10H16O

Ingredient ID: TCMC5950
Formula: C12H18O2

Ingredient ID: TCMC535
Formula: C16H16O5

Ingredient ID: TCMC5325
Formula: C15H24

Ingredient ID: TCMC5158
Formula: C12H20O4

Ingredient ID: TCMC5077
Formula: C15H24

Ingredient ID: TCMC5070
Formula: C15H24

Ingredient ID: TCMC4932
Formula: C16H24O4

Ingredient ID: TCMC493
Formula: C8H10O2

Ingredient ID: TCMC4751
Formula: C13H26O

Ingredient ID: TCMC4568
Formula: C10H16

Ingredient ID: TCMC4432
Formula: C12H14O3

Ingredient ID: TCMC4324
Formula: C29H48O

Ingredient ID: TCMC4259
Formula: C12H16O2

Ingredient ID: TCMC402
Formula: C16H32O

Ingredient ID: TCMC401
Formula: C14H12O3

Ingredient ID: TCMC400
Formula: C14H12O3

Ingredient ID: TCMC395
Formula: C9H16O

Ingredient ID: TCMC3942
Formula: C10H16

Ingredient ID: TCMC392
Formula: C11H10

Ingredient ID: TCMC391
Formula: C5H6O

Ingredient ID: TCMC3882
Formula: C15H24

Ingredient ID: TCMC387
Formula: C10H16O

Ingredient ID: TCMC3583
Formula: C12H18O2

Ingredient ID: TCMC345
Formula: C19H19N7O6

Ingredient ID: TCMC3390
Formula: C10H16O4

Ingredient ID: TCMC3321
Formula: C10H16

Ingredient ID: TCMC3307
Formula: C15H24

Ingredient ID: TCMC326
Formula: C8H8O3

Ingredient ID: TCMC320
Formula: C8H10O

Ingredient ID: TCMC3163
Formula: C8H10O

Ingredient ID: TCMC3107
Formula: C11H20O4

Ingredient ID: TCMC3049
Formula: C8H10O

Ingredient ID: TCMC304
Formula: C10H18O

Ingredient ID: TCMC3032
Formula: C24H48O2

Ingredient ID: TCMC2995
Formula: C10H12O

Ingredient ID: TCMC2974
Formula: C10H10O4

Ingredient ID: TCMC2968
Formula: C14H30O

Ingredient ID: TCMC2945
Formula: C12H22O4

Ingredient ID: TCMC289
Formula: C5H12O

Ingredient ID: TCMC2879
Formula: C10H18O4

Ingredient ID: TCMC2865
Formula: C9H16O4

Ingredient ID: TCMC2862
Formula: C4H4N2O2

Ingredient ID: TCMC284
Formula: C10H16

Ingredient ID: TCMC2838
Formula: C7H8O

Ingredient ID: TCMC2714
Formula: C20H28O4

Ingredient ID: TCMC27
Formula: C14H14O4

Ingredient ID: TCMC2671
Formula: C8H14O