Component: Kadsura heteroclita 异型南五味子

Description of the Component

Component ID
Latin Name
Kadsura heteroclita
English Name
Curious kadsura
Chinese Pinyin Name
Yi Xing Nan Wu Wei Zi
TCM Properties
TCM Meridians
Therapeutic Class English
Therapeutic Class Chinese
Geo-authentic habitats (道地产区)
Chinese Pharmacopoeia (2015)
Barcode ID
Barcode Source

TCM Prescriptions with the Component

Prescription ID Prescription English Name Prescription Chinese Name
TCMFx4317 Huo Luo Jian Shen Oral Liquid 活络健身液
TCMFx5955 Si Teng Tablets 四藤片

Targeted Human Proteins by the Ingredient of Component

Target ID Gene Symbol Target Name Target Class Uniprot ID
TCMT273 NR1H4 Bile acid receptor FXR Nuclear receptor Q96RI1
TCMT281 DPP4 Dipeptidyl peptidase IV Unclassified P27487
TCMT33 CYP3A4 Cytochrome P450 3A4 Oxidoreductase P08684
TCMT34 CYP2D6 Cytochrome P450 2D6 Oxidoreductase P10635
TCMT41 IDH1 Isocitrate dehydrogenase [NADP] cytoplasmic Oxidoreductase O75874
TCMT558 TOP2A DNA topoisomerase II alpha Isomerase P11388
TCMT99 SHBG Testis-specific androgen-binding protein Unclassified P04278

Targeted Pathogenic Microbes by the Ingredient of Component

Target ID Target Name
TCMT1382 Plasmodium falciparum (isolate K1 / Thailand)
TCMT1438 Plasmodium falciparum
TCMT1463 Mycobacterium tuberculosis
TCMT1465 Entamoeba histolytica

Ingredient Structrues

Ingredient ID: TCMC801
Formula: C29H50O

Ingredient ID: TCMC2478
Formula: C30H40O4

Ingredient ID: TCMC1515
Formula: C30H50O

Ingredient ID: TCMC1192
Formula: C30H50O

Ingredient ID: TCMC1
Formula: C20H24O5


Ingredient ID Formulae Name MW AlogP MlogP XlogP # HBA # HBD PSA # Rotatable Bond # Ring # Heacy Atom Lipinski RO5 Violation
TCMC1 C20H24O5 (-)-3,4-Divanillyltetrahydrofuran 344.16 -1.1249 3.11 2.726 1 2 68.15 10 3 25 0
TCMC801 C29H50O Beta-Sitosterol 414.39 1.3 4.54 11.595 1 1 20.23 13 4 30 1
TCMC1192 C30H50O Friedeline 426.39 3.2175 4.65 12.613 1 0 17.07 8 5 31 1
TCMC1515 C30H50O Lupeol 426.39 3.2313 4.65 11.901 1 1 20.23 9 5 31 1
TCMC2478 C30H40O4 Pristimerin 464.29 2.7341 4.32 8.301 4 1 63.6 10 5 34 1

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1. General Information of the Component  
2. TCM Prescriptions with the Component  
3. Putative Targets  
4. Activity & References for Filtering Putative Targets  
5. Ingredient Data & Chemical Structure Information (Properties, InChI, InChIkey, SMILES, etc.)