Component: Aristolochia debilis 青木香

Description of the Component

Component ID
Latin Name
Aristolochia debilis
English Name
Slender dutchmanspipe root
Chinese Pinyin Name
Qing Mu Xiang
TCM Properties
TCM Meridians
Therapeutic Class English
Regulation of qi
Therapeutic Class Chinese
relieve pain by subduing hyperactivity of the liver, and counteract toxicity and cause subsidence of swelling
Geo-authentic habitats (道地产区)
Chinese Pharmacopoeia (2015)
Barcode ID
Barcode Source

TCM Prescriptions with the Component

Prescription ID Prescription English Name Prescription Chinese Name
TCMF3598 Feng Tong Pills 风痛丸
TCMF3703 Guan Jie Zhen Tong Ointment 关节镇痛膏
TCMFx3848 Guan Xin Su He Capsules 冠心苏合胶囊
TCMFx3840 Guan Xin Su He Di Pills 冠心苏合滴丸
TCMFx4893 Kang Fu Ruan Ointment 康妇软膏
TCMFx4965 Lv Xue 绿雪
TCMFx4973 Lv Xue Capsules 绿雪胶囊
TCMFx1716 Pills for Coronary Heart Disease 冠心苏合丸
TCMFx2591 Pressure Relieving Decoction
TCMFx4841 Qi Men She Yao Tablets 祁门蛇药片
TCMF5193 San Yu Shen Qu 三余神曲
TCMF3352 Shen Mei Yang Wei Infusion 参梅养胃冲剂
TCMF3392 Shen Qi Jian Wei Infusion 参芪健胃冲剂
TCMF2617 Shixiang Fansheng Pills 十香返生丸
TCMF1438 Shixiang Fansheng Pills 十香返生丸
TCMF5309 Shu Gan Li Qi Pills 舒肝理气丸
TCMFx5726 Shuang Xiang Pai Shi Granules 双香排石颗粒
TCMFx1255 Storax Pill for Coronary Heart Disease; Storax Pill for Treating Coronary Heart Disease 冠心苏合丸
TCMFx5900 Wei Yao Capsules 胃药胶囊
TCMFx6903 Wu Song Zhong Tong Ding 五松肿痛酊
TCMF6020 Xin Wu You Tablets 心无忧片
TCMF6820 Yang Wei Ning Capsules 养胃宁胶囊
TCMFx6077 Yang Yin Jiang Ye Capsules 养阴降压胶囊

Targeted Human Proteins by the Ingredient of Component

Target ID Gene Symbol Target Name Target Class Uniprot ID
TCMT133 CA1 Carbonic anhydrase I Lyase P00915
TCMT134 CA2 Carbonic anhydrase II Lyase P00918
TCMT135 CA14 Carbonic anhydrase XIV Lyase Q9ULX7
TCMT136 CA12 Carbonic anhydrase XII Lyase O43570
TCMT137 CA9 Carbonic anhydrase IX Lyase Q16790
TCMT138 CA7 Carbonic anhydrase VII Lyase P43166
TCMT139 CA6 Carbonic anhydrase VI Lyase P23280
TCMT140 CA5B Carbonic anhydrase VB Lyase Q9Y2D0
TCMT141 CA5A Carbonic anhydrase VA Lyase P35218
TCMT142 CA4 Carbonic anhydrase IV Lyase P22748
TCMT143 CA3 Carbonic anhydrase III Lyase P07451
TCMT150 RORC Nuclear receptor ROR-gamma Nuclear receptor P51449
TCMT159 TYR Tyrosinase Oxidoreductase P14679
TCMT161 HCAR2 Hydroxycarboxylic acid receptor 2 GPCR Q8TDS4
TCMT162 UGT1A1 UDP-glucuronosyltransferase 1-1 Transferase P22309
TCMT166 AKR1C2 Aldo-keto reductase family 1 member C2 Oxidoreductase P52895
TCMT167 AKR1C3 Aldo-keto-reductase family 1 member C3 Oxidoreductase P42330
TCMT168 AKR1C4 Aldo-keto reductase family 1 member C4 Oxidoreductase P17516
TCMT2 MAPT Microtubule-associated protein tau Unclassified P10636
TCMT223 AKR1B1 Aldose reductase Oxidoreductase P15121
TCMT236 ESR2 Estrogen receptor beta Nuclear receptor Q92731
TCMT280 AKR1B10 Aldo-keto reductase family 1 member B10 Oxidoreductase O60218
TCMT281 DPP4 Dipeptidyl peptidase IV Unclassified P27487
TCMT33 CYP3A4 Cytochrome P450 3A4 Oxidoreductase P08684
TCMT34 CYP2D6 Cytochrome P450 2D6 Oxidoreductase P10635
TCMT41 IDH1 Isocitrate dehydrogenase [NADP] cytoplasmic Oxidoreductase O75874
TCMT80 MAPK1 MAP kinase ERK2 Kinase P28482
TCMT82 ESR1 Estrogen receptor alpha Nuclear receptor P03372

Targeted Pathogenic Microbes by the Ingredient of Component

Target ID Target Name
TCMT1212 Verticillium dahliae
TCMT1246 Escherichia coli
TCMT1253 Penicillium chrysogenum
TCMT1438 Plasmodium falciparum
TCMT1444 Fusarium oxysporum
TCMT1454 Bacillus subtilis
TCMT1462 Streptococcus mutans
TCMT1465 Entamoeba histolytica

Ingredient Structrues

Ingredient ID: TCMC948
Formula: C9H8O3

Ingredient ID: TCMC872
Formula: C10H14O

Ingredient ID: TCMC801
Formula: C29H50O

Ingredient ID: TCMC723
Formula: C17H11NO8

Ingredient ID: TCMC722
Formula: C17H11NO7

Ingredient ID: TCMC655
Formula: C4H6N4O3

Ingredient ID: TCMC2541
Formula: C10H18O

Ingredient ID: TCMC2383
Formula: C20H23NO4

Ingredient ID: TCMC2222
Formula: C8H8O4

Ingredient ID: TCMC2119
Formula: C9H10O5

Ingredient ID: TCMC170
Formula: C10H14O

Ingredient ID: TCMC1663
Formula: C38H42N2O6

Ingredient ID: TCMC1157
Formula: C10H18O


Ingredient ID Formulae Name MW AlogP MlogP XlogP # HBA # HBD PSA # Rotatable Bond # Ring # Heacy Atom Lipinski RO5 Violation
TCMC170 C10H14O (S)(+)Carvone 150.1 1.5954 2.45 1.756 1 0 17.07 3 1 11 0
TCMC655 C4H6N4O3 Allantoin 158.04 -0.2279 1.13 -0.469 7 5 121.29 5 1 11 0
TCMC722 C17H11NO7 Aristolochic Acid 341.05 0.0658 2.45 2.79 2 1 108.13 6 4 25 0
TCMC723 C17H11NO8 Aristolochic D 357.05 -0.3945 2.34 1.616 2 2 128.36 7 4 26 0
TCMC801 C29H50O Beta-Sitosterol 414.39 1.3 4.54 11.595 1 1 20.23 13 4 30 1
TCMC872 C10H14O Carvacrol 150.1 0.7546 2.45 3.556 0 1 20.23 5 1 11 0
TCMC948 C9H8O3 Coumaric Acid 164.05 -0.339 2.12 1.886 2 2 57.53 4 1 12 0
TCMC1157 C10H18O Eucalyptol 154.14 1.3109 2.45 2.595 1 0 9.23 3 0 11 0
TCMC1663 C38H42N2O6 622.3 0.274 4.76 6.098 2 0 61.86 10 6 46 1
TCMC2119 C9H10O5 Syringic Acid 198.05 -0.8037 1.9 0.182 2 2 75.99 7 1 14 0
TCMC2222 C8H8O4 Vanillic Acid 168.04 -0.7519 1.9 0.626 2 2 66.76 5 1 12 0
TCMC2383 C20H23NO4 Magnoflorine 342.17 -1.9843 3.11 1.008 0 2 58.92 8 4 25 0
TCMC2541 C10H18O Alpha-Terpineol 154.14 1.1223 2.45 2.369 1 1 20.23 5 1 11 0

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1. General Information of the Component  
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3. Putative Targets  
4. Activity & References for Filtering Putative Targets  
5. Ingredient Data & Chemical Structure Information (Properties, InChI, InChIkey, SMILES, etc.)