Component: Origanum vulgare 牛至


Description of the Component

Component ID
 TCMH1592
Latin Name
 Origanum vulgare
English Name
 wild marjoram
Chinese Pinyin Name
 Niu Zhi
中文名
 牛至
TCM Properties
TCM Meridians
Therapeutic Class English
Therapeutic Class Chinese
Functions
Toxicity
 NA
Geo-authentic habitats (道地产区)
 NA
Reference
 Chinese Pharmacopoeia (2015)
Barcode ID
 ITSAL862-14
Barcode Source
 BOLDSYSTEMS

TCM Prescriptions with the Component

Prescription ID Prescription English Name Prescription Chinese Name
TCMF4575 Ji Gu Cao Capsules 鸡骨草胶囊
TCMF417 Wu Jun Zhi Dan Tablet 乌军治胆片
TCMF5261 Wu Jun Zhi Dan Tablets 乌军治胆片

Targeted Human Proteins by the Ingredient of Component

Target ID Gene Symbol Target Name Target Class Uniprot ID
TCMT130 ALOX5 Arachidonate 5-lipoxygenase Oxidoreductase P09917
TCMT133 CA1 Carbonic anhydrase I Lyase P00915
TCMT134 CA2 Carbonic anhydrase II Lyase P00918
TCMT135 CA14 Carbonic anhydrase XIV Lyase Q9ULX7
TCMT136 CA12 Carbonic anhydrase XII Lyase O43570
TCMT137 CA9 Carbonic anhydrase IX Lyase Q16790
TCMT138 CA7 Carbonic anhydrase VII Lyase P43166
TCMT139 CA6 Carbonic anhydrase VI Lyase P23280
TCMT142 CA4 Carbonic anhydrase IV Lyase P22748
TCMT156 CYP19A1 Cytochrome P450 19A1 Oxidoreductase P11511
TCMT162 UGT1A1 UDP-glucuronosyltransferase 1-1 Transferase P22309
TCMT17 POLB DNA polymerase beta Transferase P06746
TCMT18 GAA Lysosomal alpha-glucosidase Hydrolase P10253
TCMT2 MAPT Microtubule-associated protein tau Unclassified P10636
TCMT207 BACE1 Beta-secretase 1 Protease P56817
TCMT213 SLC22A1 Solute carrier family 22 member 1 Transporter O15245
TCMT223 AKR1B1 Aldose reductase Oxidoreductase P15121
TCMT295 MMP1 Matrix metalloproteinase-1 Hydrolase P03956
TCMT3 ALOX15 Arachidonate 15-lipoxygenase Oxidoreductase P16050
TCMT306 MMP2 Matrix metalloproteinase-2 Hydrolase P08253
TCMT320 MMP3 Matrix metalloproteinase 3 Hydrolase P08254
TCMT321 MMP9 Matrix metalloproteinase 9 Hydrolase P14780
TCMT327 TRPV1 Vanilloid receptor Ion channel Q8NER1
TCMT33 CYP3A4 Cytochrome P450 3A4 Oxidoreductase P08684
TCMT609 CTSL Cathepsin L Unclassified P07711
TCMT69 THRB Thyroid hormone receptor beta-1 Nuclear receptor P10828
TCMT8 KDM4E Lysine-specific demethylase 4D-like Oxidoreductase B2RXH2
TCMT82 ESR1 Estrogen receptor alpha Nuclear receptor P03372


Targeted Pathogenic Microbes by the Ingredient of Component

Target ID Target Name
TCMT1178 Actinomyces viscosus
TCMT1209 Staphylococcus haemolyticus
TCMT1210 Streptococcus sobrinus
TCMT1211 Fusobacterium nucleatum
TCMT1218 Staphylococcus aureus
TCMT1223 Staphylococcus epidermidis
TCMT1226 Klebsiella pneumoniae
TCMT1229 Enterococcus faecalis
TCMT1246 Escherichia coli
TCMT1251 Candida albicans
TCMT1321 Staphylococcus hominis
TCMT1343 Staphylococcus simulans
TCMT1344 Staphylococcus sciuri
TCMT1370 Prevotella melaninogenica
TCMT1444 Fusarium oxysporum
TCMT1448 Enterobacter aerogenes
TCMT1462 Streptococcus mutans
TCMT1463 Mycobacterium tuberculosis

Ingredient Structrues

Ingredient ID: TCMC872
Formula: C10H14O

Ingredient ID: TCMC598
Formula: C21H22O4

Ingredient ID: TCMC2691
Formula: C32H52O2

Ingredient ID: TCMC2186
Formula: C30H62

Ingredient ID: TCMC2166
Formula: C10H14O

Ingredient ID: TCMC1956
Formula: C7H6O4

Ingredient ID: TCMC1535
Formula: C6H14O6

Ingredient ID: TCMC1374
Formula: C6H12O6

Ingredient ID: TCMC1239
Formula: C12H20O2

Properties

Ingredient ID Formulae Name MW AlogP MlogP XlogP # HBA # HBD PSA # Rotatable Bond # Ring # Heacy Atom Lipinski RO5 Violation
TCMC598 C21H22O4 9-[(2E)-3,7-Dimethylocta-2,6-Dienoxy]Furo[3,2-G]Chromen-7-One 338.15 2.7618 3.33 4.713 1 0 48.67 9 3 25 0
TCMC872 C10H14O Carvacrol 150.1 0.7546 2.45 3.556 0 1 20.23 5 1 11 0
TCMC1239 C12H20O2 Geranyl Acetate 196.15 2.7188 2.56 3.264 2 0 26.3 10 0 14 0
TCMC1374 C6H12O6 Inositol 180.06 -3.0642 1.46 -1.458 6 6 121.38 6 1 12 1
TCMC1535 C6H14O6 Mannitol 182.08 -2.9402 1.46 -3.896 6 6 121.38 11 0 12 1
TCMC1956 C7H6O4 Protocatechuic Acid 154.03 -1.1604 1.79 0.536 2 3 77.76 4 1 11 0
TCMC2166 C10H14O Thymol 150.1 0.7546 2.45 3.556 0 1 20.23 5 1 11 0
TCMC2186 C30H62 Triacontane 422.49 -7.9614 4.76 17.41 0 0 0 29 0 30 2
TCMC2691 C32H52O2 Lupenyl Acetate 468.4 3.6104 4.76 12.641 2 0 26.3 11 5 34 1

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