TCM-ID Component

Description of the Component

Component ID	TCMH583
Latin Name	Apis cerana
English Name	Honey
Chinese Pinyin Name	Feng Mi
中文名	蜂蜜
TCM Properties	Mild,Sweet
TCM Meridians	Lung,Spleen,Large Intestine
Therapeutic Class English	Purging
Therapeutic Class Chinese	泻下
Functions	replenish the spleen and stomach, relieve dryness, alleviate pain, and counteract toxicity
Toxicity	NA
Geo-authentic habitats (道地产区)	NA
Reference	Chinese Pharmacopoeia (2015)
Barcode ID	AGIRI284-17
Barcode Source	BOLDSYSTEMS

TCM Prescriptions with the Component

Prescription ID	Prescription English Name	Prescription Chinese Name
TCMFx1269	Bolus for Invigorating Yin, Bolus for Replenishing Vital Essence	大补阴丸
TCMFx1796	Bolus for Invigorating Yin, Bolus for Replenishing Vital Essence	大补阴丸
TCMF2024	Budai Pill	布袋丸
TCMFx1919	Cannabis pills	麻子仁丸
TCMFx1683	Children's Indigestion Powder	一捻金
TCMFx6948	Cong Rong Tong Bian Oral Liquid	苁蓉通便口服液
TCMF1916	Coughing of Blood Formula	咳血方
TCMFx1536	Decoction of Larger Dosage of Pinelliae	大半夏汤
TCMFx6941	Di Huang Run Tong Oral Liquid	地黄润通口服液
TCMFx6896	Fu Fang Lian Xin Oral Liquid	复方莲芯口服液
TCMFx2671	Hemp Seed Pill	麻子仁丸
TCMFx4573	Hou Tong Pills	喉痛丸
TCMF1813	Intestine Lubricating Pills	润肠丸
TCMFx7149	Jie Bai Tablets	洁白片
TCMFx6879	Ke Chuan An Oral Liquid	咳喘安口服液
TCMFx1789	Oral Liquid of Ginseng and Royal Jelly	人参蜂皇浆
TCMF2398	Oral Liquid of Taishan Lucid Ganoderma
TCMF2140	Powder for Clearing Away Heat in Upper or Middle Jiao	凉膈散
TCMFx1666	Qiongyu Extractum	琼玉膏
TCMFx5587	Rong Xue Bu Nao Oral Liquid	茸血补脑液
TCMFx7020	Sai Long Feng Shi Wine	塞隆风湿酒
TCMF6871	Tian Qi Recipe	天杞合剂
TCMFx5795	Wei Teng Ning Tablets	胃疼宁片
TCMFx5447	Wu Jia Shen Jing	五加参精
TCMFx6955	Xiong Dan Chuan Bei Oral Liquid	熊胆川贝口服液
TCMFx6402	Xue Li Mi Ointment	雪梨蜜膏
TCMFx1244	Yinianjin Powder for Infants; Children's Indigestion Powder	一捻金

Targeted Human Proteins by the Ingredient of Component

Target ID	Gene Symbol	Target Name	Target Class	Uniprot ID
TCMT1	EHMT2	Histone-lysine N-methyltransferase, H3 lysine-9 specific 3	Transferase	Q96KQ7
TCMT162	UGT1A1	UDP-glucuronosyltransferase 1-1	Transferase	P22309
TCMT2	MAPT	Microtubule-associated protein tau	Unclassified	P10636
TCMT213	SLC22A1	Solute carrier family 22 member 1	Transporter	O15245
TCMT221	ABCB11	Bile salt export pump	Transporter	O95342
TCMT241	CHRNA7	Neuronal acetylcholine receptor protein alpha-7 subunit	Ion channel	P36544
TCMT242	HRH3	Histamine H3 receptor	GPCR	Q9Y5N1
TCMT244	HRH1	Histamine H1 receptor	GPCR	P35367
TCMT245	HRH2	Histamine H2 receptor	GPCR	P25021
TCMT246	HRH4	Histamine H4 receptor	GPCR	Q9H3N8
TCMT290	CHRM5	Muscarinic acetylcholine receptor M5	GPCR	P08912
TCMT291	CHRM3	Muscarinic acetylcholine receptor M3	GPCR	P20309
TCMT292	CHRM1	Muscarinic acetylcholine receptor M1	GPCR	P11229
TCMT293	CHRM2	Muscarinic acetylcholine receptor M2	GPCR	P08172
TCMT551	CHRM4	Muscarinic acetylcholine receptor M4	GPCR	P08173
TCMT552	CHRNA3	Neuronal acetylcholine receptor subunit alpha-3	Ion channel	P32297
TCMT8	KDM4E	Lysine-specific demethylase 4D-like	Oxidoreductase	B2RXH2

Targeted Pathogenic Microbes by the Ingredient of Component

Target ID	Target Name
TCMT1438	Plasmodium falciparum

Ingredient Structrues

Ingredient ID: TCMC619
Formula: C7H16NO2

Common Name	Acetylcholine
IUPAC Name	2-acetyloxyethyl(trimethyl)azanium
Canonical SMILES	CC(=O)OCC[N+](C)(C)C
Standard InCHI	InChI=1S/C7H16NO2/c1-7(9)10-6-5-8(2,3)4/h5-6H2,1-4H3/q+1
Standard InCHIKey	OIPILFWXSMYKGL-UHFFFAOYSA-N
External Identifiers	ChEMBL [CHEMBL667]; PubChem [187];
Reference of Component-Ingredient Pair	29246838

Occurrence of the ingredient across TCM components

Component ID	Latin Name	Pinyin Name	Chinese Name
TCMH2630	Citrus aurantium	Zhi Shi	枳实
TCMH429	Swertia chinensis	Dang Yao	当药
TCMH317	Capsella bursa-pastoris	Ci Cai	荠菜
TCMH2710	Homo sapiens	Zi He Che	紫河车
TCMH2462	Crataegus pinnatifida	Ye Shan Zha	野山楂
TCMH1322	Solanum nigrum	Long Kui	龙葵
TCMH1484	Apis cerana	Mi La	蜜蜡
TCMH737	Crataegus pinnatifida	Guang Shan Zha	广山楂
TCMH1848	Crataegus pinnatifida	Shan Zha	山楂
TCMH1849	Crataegus pinnatifida	Shan Zha Chou Gao	山楂稠膏
TCMH1852	Crataegus pinnatifida	Shan Zha Qing Gao	山楂清膏
TCMH1853	Crataegus pinnatifida	Shan Zha Tan	山楂炭
TCMH1734	Homo sapiens	Ren Zhong Bai	人中白
TCMH583	Apis cerana	Feng Mi	蜂蜜
TCMH253	Citrus aurantium	Cheng Pi	橙皮
TCMH2613	Citrus aurantium	Zhi Geng	枳梗
TCMH2618	Citrus aurantium	Zhi Ke	枳壳
TCMH2619	Citrus aurantium	Zhi Ke Gan Jin Gao	枳壳干浸膏

Ingredient ID: TCMC386
Formula: C31H46O2

Common Name	2-Methyl-3-[(E)-3,7,11,15-Tetramethylhexadec-2-Enyl]Naphthalene-1,4-Dione
IUPAC Name	2-methyl-3-[(E)-3,7,11,15-tetramethylhexadec-2-enyl]naphthalene-1,4-dione
Canonical SMILES	CC(CCCC(CCCC(C)C)C)CCC/C(=C/CC1=C(C)C(=O)c2c(C1=O)cccc2)/C
Standard InCHI	InChI=1S/C31H46O2/c1-22(2)12-9-13-23(3)14-10-15-24(4)16-11-17-25(5)20-21-27-26(6)30(32)28-18-7-8-19-29(28)31(27)33/h7-8,18-20,22-24H,9-17,21H2,1-6H3/b25-20+
Standard InCHIKey	MBWXNTAXLNYFJB-LKUDQCMESA-N
External Identifiers	ChEMBL [CHEMBL520156]; PubChem [5280483];
Reference of Component-Ingredient Pair	N/A

Occurrence of the ingredient across TCM components

Component ID	Latin Name	Pinyin Name	Chinese Name
TCMH2538	Zea mays	Yu Mi Xu	玉米须
TCMH2244	Prunella vulgaris	Xia Ku Cao	夏枯草
TCMH1409	Cannabis sativa	Ma Ren	麻仁
TCMH1499	Changium smyrnioides	Ming Dang Shen	明党参
TCMH226	Camellia sinensis	Cha Ye	茶叶
TCMH1484	Apis cerana	Mi La	蜜蜡
TCMH321	Rosa roxburghii	Ci Li Guo	刺梨果
TCMH1381	Folium camelliae sinensis	Lv Cha	绿茶
TCMH583	Apis cerana	Feng Mi	蜂蜜
TCMH1005	Cannabis sativa	Huo Ma Ren	火麻仁
TCMH51	Camellia sinensis	Bai Cha	白茶

Ingredient ID: TCMC1976
Formula: C8H11NO3

Common Name	Pyridoxine
IUPAC Name	4,5-bis(hydroxymethyl)-2-methylpyridin-3-ol
Canonical SMILES	OCc1c(CO)cnc(c1O)C
Standard InCHI	InChI=1S/C8H11NO3/c1-5-8(12)7(4-11)6(3-10)2-9-5/h2,10-12H,3-4H2,1H3
Standard InCHIKey	LXNHXLLTXMVWPM-UHFFFAOYSA-N
External Identifiers	ChEMBL [CHEMBL1364]; PubChem [1054];
Reference of Component-Ingredient Pair	22536923

Occurrence of the ingredient across TCM components

Component ID	Latin Name	Pinyin Name	Chinese Name
TCMH382	Allium sativum	Da Suan	大蒜
TCMH143	Albizia julibrissin	Bei He Huan	北合欢
TCMH2538	Zea mays	Yu Mi Xu	玉米须
TCMH2218	Rubia cordifolia	Qian Cao Teng	茜草藤
TCMH2710	Homo sapiens	Zi He Che	紫河车
TCMH1484	Apis cerana	Mi La	蜜蜡
TCMH1502	Agaricus campestris	Mo Gu	蘑菇
TCMH661	Euphorbia kansui	Gan Sui	甘遂
TCMH665	Saccharum sinensis	Gan Zhe	甘蔗
TCMH1734	Homo sapiens	Ren Zhong Bai	人中白
TCMH583	Apis cerana	Feng Mi	蜂蜜

Ingredient ID: TCMC1454
Formula: C10H12N2O3

Common Name	Kynurenine
IUPAC Name	2-amino-4-(2-aminophenyl)-4-oxobutanoic acid
Canonical SMILES	OC(=O)C(CC(=O)c1ccccc1N)N
Standard InCHI	InChI=1S/C10H12N2O3/c11-7-4-2-1-3-6(7)9(13)5-8(12)10(14)15/h1-4,8H,5,11-12H2,(H,14,15)
Standard InCHIKey	YGPSJZOEDVAXAB-UHFFFAOYSA-N
External Identifiers	ChEMBL [CHEMBL1377927]; PubChem [846];
Reference of Component-Ingredient Pair	N/A

Occurrence of the ingredient across TCM components

Component ID	Latin Name	Pinyin Name	Chinese Name
TCMH2710	Homo sapiens	Zi He Che	紫河车
TCMH1484	Apis cerana	Mi La	蜜蜡
TCMH1502	Agaricus campestris	Mo Gu	蘑菇
TCMH1734	Homo sapiens	Ren Zhong Bai	人中白
TCMH583	Apis cerana	Feng Mi	蜂蜜

Ingredient ID: TCMC1374
Formula: C6H12O6

Common Name	Inositol
IUPAC Name	n.a.
Canonical SMILES	O[C@@H]1[C@H](O)[C@H](O)[C@H]([C@@H]([C@H]1O)O)O
Standard InCHI	InChI=1S/C6H12O6/c7-1-2(8)4(10)6(12)5(11)3(1)9/h1-12H/t1-,2-,3-,4+,5-,6-
Standard InCHIKey	CDAISMWEOUEBRE-GPIVLXJGSA-N
External Identifiers	ChEMBL [CHEMBL1222251]; PubChem [N/A];
Reference of Component-Ingredient Pair	N/A

Occurrence of the ingredient across TCM components

Component ID	Latin Name	Pinyin Name	Chinese Name
TCMH521	Typhonium giganteum	Du Jiao Lian	独角莲
TCMH457	Euphorbia humifusa	Di Mian Cao	地绵草
TCMH2630	Citrus aurantium	Zhi Shi	枳实
TCMH429	Swertia chinensis	Dang Yao	当药
TCMH1969	Aconitum carmichaeli	Shu Fu Pian	熟附片
TCMH2538	Zea mays	Yu Mi Xu	玉米须
TCMH2515	Papaver somniferum	Ying Su Ke	罂粟壳
TCMH2710	Homo sapiens	Zi He Che	紫河车
TCMH1105	Trollius chinensis	Jin Lian Hua	金莲花
TCMH2286	Berberis julianae	Xiao Bo Gen	小檗根
TCMH1484	Apis cerana	Mi La	蜜蜡
TCMH1601	Nelumbo nucifera	Ou Pian	藕片
TCMH74	Patrinia villosa	Bai Jiang	败酱
TCMH1033	Centella asiatica	Ji Xue Cao	积雪草
TCMH1394	Capparis masaikai	Ma Bing Lang	马槟榔
TCMH1592	Origanum vulgare	Niu Zhi	牛至
TCMH1531	Akebia quinata	Mu Tong	木通
TCMH1714	Lonicera japonica	Ren Dong Teng	忍冬藤
TCMH13	Artemisia argyi	Ai Ye You	艾叶油
TCMH2509	Epimedium brevicornum	Yin Yang Huo Jin Gao	淫羊藿浸膏
TCMH1127	Lonicera japonica	Jin Yin Hua	金银花
TCMH1128	Lonicera japonica	Jin Yin Hua Ti Qu Ye	金银花提取液
TCMH1734	Homo sapiens	Ren Zhong Bai	人中白
TCMH583	Apis cerana	Feng Mi	蜂蜜
TCMH12	Artemisia argyi	Ai Ye	艾叶
TCMH399	Aconitum carmichaeli	Dan Fu Pian	淡附片
TCMH613	Aconitum carmichaeli	Fu Pian	附片
TCMH623	Aconitum carmichaeli	Fu Zi	附子
TCMH624	Aconitum carmichaeli	Fu Zi Ren	附子仁
TCMH1898	Aconitum carmichaeli	Sheng Fu Zi	生附子
TCMH1968	Aconitum carmichaeli	Shu Fu Kuai	熟附块
TCMH58	Typhonium giganteum	Bai Fu Zi	白附子
TCMH2507	Epimedium brevicornum	Yin Yang Huo	淫羊藿
TCMH2508	Epimedium brevicornum	Yin Yang Huo Gan Gao Fen	淫羊藿干膏粉
TCMH814	Nelumbo nucifera	He Geng	荷梗
TCMH825	Nelumbo nucifera	He Ye	荷叶
TCMH1275	Nelumbo nucifera	Lian Zi	莲子
TCMH1276	Nelumbo nucifera	Lian Zi Xin	莲子心
TCMH1598	Nelumbo nucifera	Ou	藕
TCMH1599	Nelumbo nucifera	Ou Fen	藕粉
TCMH454	Euphorbia humifusa	Di Jin Cao	地锦草
TCMH253	Citrus aurantium	Cheng Pi	橙皮
TCMH2613	Citrus aurantium	Zhi Geng	枳梗
TCMH2618	Citrus aurantium	Zhi Ke	枳壳
TCMH2619	Citrus aurantium	Zhi Ke Gan Jin Gao	枳壳干浸膏
TCMH1489	Papaver somniferum	Mi Ying Su Ke	蜜罂粟壳
TCMH2514	Papaver somniferum	Ying Su	罂粟

Ingredient ID: TCMC1330
Formula: C5H9N3

Common Name	Histamine
IUPAC Name	2-(1H-imidazol-5-yl)ethanamine
Canonical SMILES	NCCc1cnc[nH]1
Standard InCHI	InChI=1S/C5H9N3/c6-2-1-5-3-7-4-8-5/h3-4H,1-2,6H2,(H,7,8)
Standard InCHIKey	NTYJJOPFIAHURM-UHFFFAOYSA-N
External Identifiers	ChEMBL [CHEMBL90]; PubChem [774];
Reference of Component-Ingredient Pair	29968805

Occurrence of the ingredient across TCM components

Component ID	Latin Name	Pinyin Name	Chinese Name
TCMH101	Chelidonium majus	Bai Qu Cai	白屈菜
TCMH2710	Homo sapiens	Zi He Che	紫河车
TCMH1484	Apis cerana	Mi La	蜜蜡
TCMH240	Plantago depressa	Che Qian Cao	车前草
TCMH1263	Cyprinus carpio	Li Yu	鲤鱼
TCMH1734	Homo sapiens	Ren Zhong Bai	人中白
TCMH583	Apis cerana	Feng Mi	蜂蜜

Properties

Ingredient ID	Formulae	Name	MW	AlogP	MlogP	XlogP	# HBA	# HBD	PSA	# Rotatable Bond	# Ring	# Heacy Atom	Lipinski RO5 Violation
TCMC386	C31H46O2	2-Methyl-3-[(E)-3,7,11,15-Tetramethylhexadec-2-Enyl]Naphthalene-1,4-Dione	450.35	2.7425	4.65	12.011	2	0	34.14	20	2	33	2
TCMC619	C7H16NO2	Acetylcholine	146.12	-1.195	1.9	-0.097	2	0	26.3	8	0	10	0
TCMC1330	C5H9N3	Histamine	111.08	-1.4467	1.68	-0.453	3	2	54.7	3	1	8	0
TCMC1374	C6H12O6	Inositol	180.06	-3.0642	1.46	-1.458	6	6	121.38	6	1	12	1
TCMC1454	C10H12N2O3	Kynurenine	208.08	-2.1257	2.01	-1.719	5	3	106.41	7	1	15	0
TCMC1976	C8H11NO3	Pyridoxine	169.07	-0.9182	1.9	-0.677	3	3	73.58	6	1	12	0

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Data Section	Select to Download
1. General Information of the Component
2. TCM Prescriptions with the Component
3. Putative Targets
4. Activity & References for Filtering Putative Targets
5. Ingredient Data & Chemical Structure Information (Properties, InChI, InChIkey, SMILES, etc.)

Component: Apis cerana 蜂蜜

Description of the Component

Component ID

Latin Name

English Name

Chinese Pinyin Name

中文名

TCM Properties

TCM Meridians

Therapeutic Class English

Therapeutic Class Chinese

Functions

Toxicity

Geo-authentic habitats (道地产区)

Reference

Barcode ID

Barcode Source

TCM Prescriptions with the Component

Targeted Human Proteins by the Ingredient of Component

Targeted Pathogenic Microbes by the Ingredient of Component

Ingredient Structrues

Ingredient ID: TCMC619

Occurrence of the ingredient across TCM components

Ingredient ID: TCMC386

Occurrence of the ingredient across TCM components

Ingredient ID: TCMC1976

Occurrence of the ingredient across TCM components

Ingredient ID: TCMC1454

Occurrence of the ingredient across TCM components

Ingredient ID: TCMC1374

Occurrence of the ingredient across TCM components

Ingredient ID: TCMC1330

Occurrence of the ingredient across TCM components

Properties

Download Data