TCM-ID Component

Description of the Component

Component ID	TCMH1898
Latin Name	Aconitum carmichaeli
English Name	Prepared common monkshood daughter root
Chinese Pinyin Name	Sheng Fu Zi
中文名	生附子
TCM Properties
TCM Meridians
Therapeutic Class English
Therapeutic Class Chinese
Functions
Toxicity	NA
Geo-authentic habitats (道地产区)	NA
Reference	Chinese Pharmacopoeia (2015)
Barcode ID	ITSAH2410-14
Barcode Source	BOLDSYSTEMS

TCM Prescriptions with the Component

Prescription ID	Prescription English Name	Prescription Chinese Name
TCMFx531	Yang He Jie Ning Ointment	阳和解凝膏

Targeted Human Proteins by the Ingredient of Component

Target ID	Gene Symbol	Target Name	Target Class	Uniprot ID
TCMT1	EHMT2	Histone-lysine N-methyltransferase, H3 lysine-9 specific 3	Transferase	Q96KQ7
TCMT11	HIF1A	Hypoxia-inducible factor 1 alpha	Transcription factor	Q16665
TCMT125	GBA	Beta-glucocerebrosidase	Hydrolase	P04062
TCMT133	CA1	Carbonic anhydrase I	Lyase	P00915
TCMT134	CA2	Carbonic anhydrase II	Lyase	P00918
TCMT135	CA14	Carbonic anhydrase XIV	Lyase	Q9ULX7
TCMT136	CA12	Carbonic anhydrase XII	Lyase	O43570
TCMT137	CA9	Carbonic anhydrase IX	Lyase	Q16790
TCMT138	CA7	Carbonic anhydrase VII	Lyase	P43166
TCMT139	CA6	Carbonic anhydrase VI	Lyase	P23280
TCMT140	CA5B	Carbonic anhydrase VB	Lyase	Q9Y2D0
TCMT141	CA5A	Carbonic anhydrase VA	Lyase	P35218
TCMT142	CA4	Carbonic anhydrase IV	Lyase	P22748
TCMT143	CA3	Carbonic anhydrase III	Lyase	P07451
TCMT150	RORC	Nuclear receptor ROR-gamma	Nuclear receptor	P51449
TCMT248	CXCL8	Interleukin-8	Unclassified	P10145
TCMT3	ALOX15	Arachidonate 15-lipoxygenase	Oxidoreductase	P16050
TCMT33	CYP3A4	Cytochrome P450 3A4	Oxidoreductase	P08684
TCMT38	DRD2	Dopamine D2 receptor	GPCR	P14416
TCMT6	NFKB1	Nuclear factor NF-kappa-B p105 subunit	Transcription factor	P19838
TCMT651	DRD3	Dopamine D3 receptor	GPCR	P35462
TCMT69	THRB	Thyroid hormone receptor beta-1	Nuclear receptor	P10828
TCMT8	KDM4E	Lysine-specific demethylase 4D-like	Oxidoreductase	B2RXH2
TCMT87	CYP2C9	Cytochrome P450 2C9	Oxidoreductase	P11712

Targeted Pathogenic Microbes by the Ingredient of Component

Target ID	Target Name
TCMT1438	Plasmodium falciparum

Ingredient Structrues

Ingredient ID: TCMC49
Formula: C10H13NO2

Common Name	(1S)-1-Methyl-1,2,3,4-Tetrahydroisoquinoline-6,7-Diol
IUPAC Name	(1S)-1-methyl-1,2,3,4-tetrahydroisoquinoline-6,7-diol
Canonical SMILES	C[C@@H]1NCCc2c1cc(O)c(c2)O
Standard InCHI	InChI=1S/C10H13NO2/c1-6-8-5-10(13)9(12)4-7(8)2-3-11-6/h4-6,11-13H,2-3H2,1H3/t6-/m0/s1
Standard InCHIKey	IBRKLUSXDYATLG-LURJTMIESA-N
External Identifiers	ChEMBL [CHEMBL1195032]; PubChem [91588];
Reference of Component-Ingredient Pair	N/A

Occurrence of the ingredient across TCM components

Component ID	Latin Name	Pinyin Name	Chinese Name
TCMH1969	Aconitum carmichaeli	Shu Fu Pian	熟附片
TCMH2215	Ficus simplicissima	Wu Zhi Mao Tao	五指毛桃
TCMH920	Quercus dentata	Hu Ye Gan Jin Gao	槲叶干浸膏
TCMH399	Aconitum carmichaeli	Dan Fu Pian	淡附片
TCMH613	Aconitum carmichaeli	Fu Pian	附片
TCMH623	Aconitum carmichaeli	Fu Zi	附子
TCMH624	Aconitum carmichaeli	Fu Zi Ren	附子仁
TCMH1898	Aconitum carmichaeli	Sheng Fu Zi	生附子
TCMH1968	Aconitum carmichaeli	Shu Fu Kuai	熟附块

Ingredient ID: TCMC486
Formula: C6H7NO

Common Name	4-Aminophenol
IUPAC Name	4-azaniumylphenolate
Canonical SMILES	Nc1ccc(cc1)O
Standard InCHI	InChI=1S/C6H7NO/c7-5-1-3-6(8)4-2-5/h1-4,8H,7H2
Standard InCHIKey	PLIKAWJENQZMHA-UHFFFAOYSA-N
External Identifiers	ChEMBL [CHEMBL1142]; PubChem [13283155];
Reference of Component-Ingredient Pair	N/A

Occurrence of the ingredient across TCM components

Component ID	Latin Name	Pinyin Name	Chinese Name
TCMH1969	Aconitum carmichaeli	Shu Fu Pian	熟附片
TCMH2710	Homo sapiens	Zi He Che	紫河车
TCMH1734	Homo sapiens	Ren Zhong Bai	人中白
TCMH399	Aconitum carmichaeli	Dan Fu Pian	淡附片
TCMH613	Aconitum carmichaeli	Fu Pian	附片
TCMH623	Aconitum carmichaeli	Fu Zi	附子
TCMH624	Aconitum carmichaeli	Fu Zi Ren	附子仁
TCMH1898	Aconitum carmichaeli	Sheng Fu Zi	生附子
TCMH1968	Aconitum carmichaeli	Shu Fu Kuai	熟附块

Ingredient ID: TCMC437
Formula: C6H7NO

Common Name	3-Aminophenol
IUPAC Name	3-aminophenol
Canonical SMILES	Nc1cccc(c1)O
Standard InCHI	InChI=1S/C6H7NO/c7-5-2-1-3-6(8)4-5/h1-4,8H,7H2
Standard InCHIKey	CWLKGDAVCFYWJK-UHFFFAOYSA-N
External Identifiers	ChEMBL [CHEMBL269755]; PubChem [11568];
Reference of Component-Ingredient Pair	22302165

Occurrence of the ingredient across TCM components

Component ID	Latin Name	Pinyin Name	Chinese Name
TCMH1969	Aconitum carmichaeli	Shu Fu Pian	熟附片
TCMH399	Aconitum carmichaeli	Dan Fu Pian	淡附片
TCMH613	Aconitum carmichaeli	Fu Pian	附片
TCMH623	Aconitum carmichaeli	Fu Zi	附子
TCMH624	Aconitum carmichaeli	Fu Zi Ren	附子仁
TCMH1898	Aconitum carmichaeli	Sheng Fu Zi	生附子
TCMH1968	Aconitum carmichaeli	Shu Fu Kuai	熟附块

Ingredient ID: TCMC2545
Formula: C6H7NO

Common Name	O-Phenylhydroxylamine
IUPAC Name	O-phenylhydroxylamine
Canonical SMILES	NOc1ccccc1
Standard InCHI	InChI=1S/C6H7NO/c7-8-6-4-2-1-3-5-6/h1-5H,7H2
Standard InCHIKey	UOKZUTXLHRTLFH-UHFFFAOYSA-N
External Identifiers	ChEMBL [CHEMBL1213940]; PubChem [2794249];
Reference of Component-Ingredient Pair	N/A

Occurrence of the ingredient across TCM components

Component ID	Latin Name	Pinyin Name	Chinese Name
TCMH1969	Aconitum carmichaeli	Shu Fu Pian	熟附片
TCMH399	Aconitum carmichaeli	Dan Fu Pian	淡附片
TCMH613	Aconitum carmichaeli	Fu Pian	附片
TCMH623	Aconitum carmichaeli	Fu Zi	附子
TCMH624	Aconitum carmichaeli	Fu Zi Ren	附子仁
TCMH1898	Aconitum carmichaeli	Sheng Fu Zi	生附子
TCMH1968	Aconitum carmichaeli	Shu Fu Kuai	熟附块

Ingredient ID: TCMC226
Formula: C16H17NO3

Common Name	1-(4-Hydroxy-Benzyl)-1,2,3,4-Tetrahydro-Isoquinoline-6,7-Diol
IUPAC Name	1-[(4-hydroxyphenyl)methyl]-1,2,3,4-tetrahydroisoquinoline-6,7-diol
Canonical SMILES	Oc1ccc(cc1)CC1NCCc2c1cc(O)c(c2)O
Standard InCHI	InChI=1S/C16H17NO3/c18-12-3-1-10(2-4-12)7-14-13-9-16(20)15(19)8-11(13)5-6-17-14/h1-4,8-9,14,17-20H,5-7H2
Standard InCHIKey	WZRCQWQRFZITDX-UHFFFAOYSA-N
External Identifiers	ChEMBL [CHEMBL19344]; PubChem [114840];
Reference of Component-Ingredient Pair	N/A

Occurrence of the ingredient across TCM components

Component ID	Latin Name	Pinyin Name	Chinese Name
TCMH1969	Aconitum carmichaeli	Shu Fu Pian	熟附片
TCMH2239	Asarum sieboldii	Xi Xin	细辛
TCMH1601	Nelumbo nucifera	Ou Pian	藕片
TCMH399	Aconitum carmichaeli	Dan Fu Pian	淡附片
TCMH613	Aconitum carmichaeli	Fu Pian	附片
TCMH623	Aconitum carmichaeli	Fu Zi	附子
TCMH624	Aconitum carmichaeli	Fu Zi Ren	附子仁
TCMH1898	Aconitum carmichaeli	Sheng Fu Zi	生附子
TCMH1968	Aconitum carmichaeli	Shu Fu Kuai	熟附块
TCMH814	Nelumbo nucifera	He Geng	荷梗
TCMH825	Nelumbo nucifera	He Ye	荷叶
TCMH1275	Nelumbo nucifera	Lian Zi	莲子
TCMH1276	Nelumbo nucifera	Lian Zi Xin	莲子心
TCMH1598	Nelumbo nucifera	Ou	藕
TCMH1599	Nelumbo nucifera	Ou Fen	藕粉

Ingredient ID: TCMC1988
Formula: C6H7NO

Common Name	Questiomycin B
IUPAC Name	2-aminophenol
Canonical SMILES	Nc1ccccc1O
Standard InCHI	InChI=1S/C6H7NO/c7-5-3-1-2-4-6(5)8/h1-4,8H,7H2
Standard InCHIKey	CDAWCLOXVUBKRW-UHFFFAOYSA-N
External Identifiers	ChEMBL [CHEMBL28319]; PubChem [5801];
Reference of Component-Ingredient Pair	26795242

Occurrence of the ingredient across TCM components

Component ID	Latin Name	Pinyin Name	Chinese Name
TCMH1969	Aconitum carmichaeli	Shu Fu Pian	熟附片
TCMH399	Aconitum carmichaeli	Dan Fu Pian	淡附片
TCMH613	Aconitum carmichaeli	Fu Pian	附片
TCMH623	Aconitum carmichaeli	Fu Zi	附子
TCMH624	Aconitum carmichaeli	Fu Zi Ren	附子仁
TCMH1898	Aconitum carmichaeli	Sheng Fu Zi	生附子
TCMH1968	Aconitum carmichaeli	Shu Fu Kuai	熟附块

Ingredient ID: TCMC1374
Formula: C6H12O6

Common Name	Inositol
IUPAC Name	n.a.
Canonical SMILES	O[C@@H]1[C@H](O)[C@H](O)[C@H]([C@@H]([C@H]1O)O)O
Standard InCHI	InChI=1S/C6H12O6/c7-1-2(8)4(10)6(12)5(11)3(1)9/h1-12H/t1-,2-,3-,4+,5-,6-
Standard InCHIKey	CDAISMWEOUEBRE-GPIVLXJGSA-N
External Identifiers	ChEMBL [CHEMBL1222251]; PubChem [N/A];
Reference of Component-Ingredient Pair	N/A

Occurrence of the ingredient across TCM components

Component ID	Latin Name	Pinyin Name	Chinese Name
TCMH521	Typhonium giganteum	Du Jiao Lian	独角莲
TCMH457	Euphorbia humifusa	Di Mian Cao	地绵草
TCMH2630	Citrus aurantium	Zhi Shi	枳实
TCMH429	Swertia chinensis	Dang Yao	当药
TCMH1969	Aconitum carmichaeli	Shu Fu Pian	熟附片
TCMH2538	Zea mays	Yu Mi Xu	玉米须
TCMH2515	Papaver somniferum	Ying Su Ke	罂粟壳
TCMH2710	Homo sapiens	Zi He Che	紫河车
TCMH1105	Trollius chinensis	Jin Lian Hua	金莲花
TCMH2286	Berberis julianae	Xiao Bo Gen	小檗根
TCMH1484	Apis cerana	Mi La	蜜蜡
TCMH1601	Nelumbo nucifera	Ou Pian	藕片
TCMH74	Patrinia villosa	Bai Jiang	败酱
TCMH1033	Centella asiatica	Ji Xue Cao	积雪草
TCMH1394	Capparis masaikai	Ma Bing Lang	马槟榔
TCMH1592	Origanum vulgare	Niu Zhi	牛至
TCMH1531	Akebia quinata	Mu Tong	木通
TCMH1714	Lonicera japonica	Ren Dong Teng	忍冬藤
TCMH13	Artemisia argyi	Ai Ye You	艾叶油
TCMH2509	Epimedium brevicornum	Yin Yang Huo Jin Gao	淫羊藿浸膏
TCMH1127	Lonicera japonica	Jin Yin Hua	金银花
TCMH1128	Lonicera japonica	Jin Yin Hua Ti Qu Ye	金银花提取液
TCMH1734	Homo sapiens	Ren Zhong Bai	人中白
TCMH583	Apis cerana	Feng Mi	蜂蜜
TCMH12	Artemisia argyi	Ai Ye	艾叶
TCMH399	Aconitum carmichaeli	Dan Fu Pian	淡附片
TCMH613	Aconitum carmichaeli	Fu Pian	附片
TCMH623	Aconitum carmichaeli	Fu Zi	附子
TCMH624	Aconitum carmichaeli	Fu Zi Ren	附子仁
TCMH1898	Aconitum carmichaeli	Sheng Fu Zi	生附子
TCMH1968	Aconitum carmichaeli	Shu Fu Kuai	熟附块
TCMH58	Typhonium giganteum	Bai Fu Zi	白附子
TCMH2507	Epimedium brevicornum	Yin Yang Huo	淫羊藿
TCMH2508	Epimedium brevicornum	Yin Yang Huo Gan Gao Fen	淫羊藿干膏粉
TCMH814	Nelumbo nucifera	He Geng	荷梗
TCMH825	Nelumbo nucifera	He Ye	荷叶
TCMH1275	Nelumbo nucifera	Lian Zi	莲子
TCMH1276	Nelumbo nucifera	Lian Zi Xin	莲子心
TCMH1598	Nelumbo nucifera	Ou	藕
TCMH1599	Nelumbo nucifera	Ou Fen	藕粉
TCMH454	Euphorbia humifusa	Di Jin Cao	地锦草
TCMH253	Citrus aurantium	Cheng Pi	橙皮
TCMH2613	Citrus aurantium	Zhi Geng	枳梗
TCMH2618	Citrus aurantium	Zhi Ke	枳壳
TCMH2619	Citrus aurantium	Zhi Ke Gan Jin Gao	枳壳干浸膏
TCMH1489	Papaver somniferum	Mi Ying Su Ke	蜜罂粟壳
TCMH2514	Papaver somniferum	Ying Su	罂粟

Properties

Ingredient ID	Formulae	Name	MW	AlogP	MlogP	XlogP	# HBA	# HBD	PSA	# Rotatable Bond	# Ring	# Heacy Atom	Lipinski RO5 Violation
TCMC49	C10H13NO2	(1S)-1-Methyl-1,2,3,4-Tetrahydroisoquinoline-6,7-Diol	179.09	-1.0729	2.23	0.899	1	3	52.49	3	2	13	0
TCMC226	C16H17NO3	1-(4-Hydroxy-Benzyl)-1,2,3,4-Tetrahydro-Isoquinoline-6,7-Diol	271.12	-1.5221	2.78	2.146	1	4	72.72	5	3	20	0
TCMC437	C6H7NO	3-Aminophenol	109.05	-1.2102	1.9	0.803	1	2	46.25	2	1	8	0
TCMC486	C6H7NO	4-Aminophenol	109.05	-1.2102	1.9	0.803	1	2	46.25	2	1	8	0
TCMC1374	C6H12O6	Inositol	180.06	-3.0642	1.46	-1.458	6	6	121.38	6	1	12	1
TCMC1988	C6H7NO	Questiomycin B	109.05	-1.2102	1.9	1.232	1	2	46.25	2	1	8	0
TCMC2545	C6H7NO	O-Phenylhydroxylamine	109.05	-0.7496	1.9	1.534	0	1	35.25	2	1	8	0

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Data Section	Select to Download
1. General Information of the Component
2. TCM Prescriptions with the Component
3. Putative Targets
4. Activity & References for Filtering Putative Targets
5. Ingredient Data & Chemical Structure Information (Properties, InChI, InChIkey, SMILES, etc.)

Component: Aconitum carmichaeli 生附子

Description of the Component

Component ID

Latin Name

English Name

Chinese Pinyin Name

中文名

TCM Properties

TCM Meridians

Therapeutic Class English

Therapeutic Class Chinese

Functions

Toxicity

Geo-authentic habitats (道地产区)

Reference

Barcode ID

Barcode Source

TCM Prescriptions with the Component

Targeted Human Proteins by the Ingredient of Component

Targeted Pathogenic Microbes by the Ingredient of Component

Ingredient Structrues

Ingredient ID: TCMC49

Occurrence of the ingredient across TCM components

Ingredient ID: TCMC486

Occurrence of the ingredient across TCM components

Ingredient ID: TCMC437

Occurrence of the ingredient across TCM components

Ingredient ID: TCMC2545

Occurrence of the ingredient across TCM components

Ingredient ID: TCMC226

Occurrence of the ingredient across TCM components

Ingredient ID: TCMC1988

Occurrence of the ingredient across TCM components

Ingredient ID: TCMC1374

Occurrence of the ingredient across TCM components

Properties

Download Data