Component: Apis cerana 蜜蜡


Description of the Component

Component ID
TCMH1484
Latin Name
Apis cerana
English Name
Bee wax
Chinese Pinyin Name
Mi La
中文名
蜜蜡
TCM Properties
TCM Meridians
Therapeutic Class English
Therapeutic Class Chinese
Functions
Toxicity
NA
Geo-authentic habitats (道地产区)
NA
Reference
Chinese Pharmacopoeia (2015)
Barcode ID
AGIRI284-17
Barcode Source
BOLDSYSTEMS

TCM Prescriptions with the Component

Prescription ID Prescription English Name Prescription Chinese Name
TCMFx2643 Purple Cloud Ointment 紫云膏
TCMFx7400 Zi Yun Gao 紫云膏

Targeted Human Proteins by the Ingredient of Component

Target ID Gene Symbol Target Name Target Class Uniprot ID
TCMT1 EHMT2 Histone-lysine N-methyltransferase, H3 lysine-9 specific 3 Transferase Q96KQ7
TCMT162 UGT1A1 UDP-glucuronosyltransferase 1-1 Transferase P22309
TCMT2 MAPT Microtubule-associated protein tau Unclassified P10636
TCMT213 SLC22A1 Solute carrier family 22 member 1 Transporter O15245
TCMT221 ABCB11 Bile salt export pump Transporter O95342
TCMT241 CHRNA7 Neuronal acetylcholine receptor protein alpha-7 subunit Ion channel P36544
TCMT242 HRH3 Histamine H3 receptor GPCR Q9Y5N1
TCMT244 HRH1 Histamine H1 receptor GPCR P35367
TCMT245 HRH2 Histamine H2 receptor GPCR P25021
TCMT246 HRH4 Histamine H4 receptor GPCR Q9H3N8
TCMT290 CHRM5 Muscarinic acetylcholine receptor M5 GPCR P08912
TCMT291 CHRM3 Muscarinic acetylcholine receptor M3 GPCR P20309
TCMT292 CHRM1 Muscarinic acetylcholine receptor M1 GPCR P11229
TCMT293 CHRM2 Muscarinic acetylcholine receptor M2 GPCR P08172
TCMT551 CHRM4 Muscarinic acetylcholine receptor M4 GPCR P08173
TCMT552 CHRNA3 Neuronal acetylcholine receptor subunit alpha-3 Ion channel P32297
TCMT8 KDM4E Lysine-specific demethylase 4D-like Oxidoreductase B2RXH2


Targeted Pathogenic Microbes by the Ingredient of Component

Target ID Target Name
TCMT1438 Plasmodium falciparum

Ingredient Structrues

Ingredient ID: TCMC619
Formula: C7H16NO2

Ingredient ID: TCMC386
Formula: C31H46O2

Ingredient ID: TCMC1976
Formula: C8H11NO3

Ingredient ID: TCMC1454
Formula: C10H12N2O3

Ingredient ID: TCMC1374
Formula: C6H12O6

Ingredient ID: TCMC1330
Formula: C5H9N3

Properties

Ingredient ID Formulae Name MW AlogP MlogP XlogP # HBA # HBD PSA # Rotatable Bond # Ring # Heacy Atom Lipinski RO5 Violation
TCMC386 C31H46O2 2-Methyl-3-[(E)-3,7,11,15-Tetramethylhexadec-2-Enyl]Naphthalene-1,4-Dione 450.35 2.7425 4.65 12.011 2 0 34.14 20 2 33 2
TCMC619 C7H16NO2 Acetylcholine 146.12 -1.195 1.9 -0.097 2 0 26.3 8 0 10 0
TCMC1330 C5H9N3 Histamine 111.08 -1.4467 1.68 -0.453 3 2 54.7 3 1 8 0
TCMC1374 C6H12O6 Inositol 180.06 -3.0642 1.46 -1.458 6 6 121.38 6 1 12 1
TCMC1454 C10H12N2O3 Kynurenine 208.08 -2.1257 2.01 -1.719 5 3 106.41 7 1 15 0
TCMC1976 C8H11NO3 Pyridoxine 169.07 -0.9182 1.9 -0.677 3 3 73.58 6 1 12 0

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1. General Information of the Component  
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3. Putative Targets  
4. Activity & References for Filtering Putative Targets  
5. Ingredient Data & Chemical Structure Information (Properties, InChI, InChIkey, SMILES, etc.)