Component: Epimedium brevicornum 淫羊藿干膏粉

Description of the Component

Component ID
Latin Name
Epimedium brevicornum
English Name
Epimedium sagittatum
Chinese Pinyin Name
Yin Yang Huo Gan Gao Fen
TCM Properties
TCM Meridians
Therapeutic Class English
Therapeutic Class Chinese
Geo-authentic habitats (道地产区)
Barcode ID
Barcode Source

TCM Prescriptions with the Component

Prescription ID Prescription English Name Prescription Chinese Name
TCMFx6663 Yi Shen Xing Yang Capsules 益肾兴阳胶囊

Targeted Human Proteins by the Ingredient of Component

Target ID Gene Symbol Target Name Target Class Uniprot ID
TCMT1 EHMT2 Histone-lysine N-methyltransferase, H3 lysine-9 specific 3 Transferase Q96KQ7
TCMT101 PTPN1 Protein-tyrosine phosphatase 1B Hydrolase P18031
TCMT125 GBA Beta-glucocerebrosidase Hydrolase P04062
TCMT130 ALOX5 Arachidonate 5-lipoxygenase Oxidoreductase P09917
TCMT133 CA1 Carbonic anhydrase I Lyase P00915
TCMT134 CA2 Carbonic anhydrase II Lyase P00918
TCMT136 CA12 Carbonic anhydrase XII Lyase O43570
TCMT138 CA7 Carbonic anhydrase VII Lyase P43166
TCMT142 CA4 Carbonic anhydrase IV Lyase P22748
TCMT156 CYP19A1 Cytochrome P450 19A1 Oxidoreductase P11511
TCMT158 EPHX2 Epoxide hydratase Lyase P34913
TCMT17 POLB DNA polymerase beta Transferase P06746
TCMT18 GAA Lysosomal alpha-glucosidase Hydrolase P10253
TCMT2 MAPT Microtubule-associated protein tau Unclassified P10636
TCMT22 ALPI Intestinal alkaline phosphatase Hydrolase P09923
TCMT223 AKR1B1 Aldose reductase Oxidoreductase P15121
TCMT23 ALPL Alkaline phosphatase, tissue-nonspecific isozyme Hydrolase P05186
TCMT260 FLT3 Tyrosine-protein kinase receptor FLT3 Kinase P36888
TCMT3 ALOX15 Arachidonate 15-lipoxygenase Oxidoreductase P16050
TCMT331 PLG Plasminogen Unclassified P00747
TCMT336 IDO1 Indoleamine 2,3-dioxygenase Oxidoreductase P14902
TCMT39 PDE5A Phosphodiesterase 5A Hydrolase O76074
TCMT401 MET Hepatocyte growth factor receptor Kinase P08581
TCMT41 IDH1 Isocitrate dehydrogenase [NADP] cytoplasmic Oxidoreductase O75874
TCMT6 NFKB1 Nuclear factor NF-kappa-B p105 subunit Transcription factor P19838
TCMT63 PPARA Peroxisome proliferator-activated receptor alpha Nuclear receptor Q07869
TCMT64 PPARD Peroxisome proliferator-activated receptor delta Nuclear receptor Q03181
TCMT67 PPARG Peroxisome proliferator-activated receptor gamma Nuclear receptor P37231
TCMT8 KDM4E Lysine-specific demethylase 4D-like Oxidoreductase B2RXH2
TCMT80 MAPK1 MAP kinase ERK2 Kinase P28482

Targeted Pathogenic Microbes by the Ingredient of Component

Target ID Target Name
TCMT1088 Carbonic anhydrase
TCMT1108 Integrase
TCMT1208 Escherichia coli K12
TCMT1212 Verticillium dahliae
TCMT1215 Pseudomonas aeruginosa PAO1
TCMT1218 Staphylococcus aureus
TCMT1223 Staphylococcus epidermidis
TCMT1251 Candida albicans
TCMT1294 Human parainfluenza virus 3
TCMT1346 Helicobacter pylori
TCMT1438 Plasmodium falciparum
TCMT1443 Leishmania amazonensis
TCMT1447 Respiratory syncytial virus
TCMT1450 Plasmodium falciparum 3D7
TCMT1463 Mycobacterium tuberculosis
TCMT1465 Entamoeba histolytica

Ingredient Structrues

Ingredient ID: TCMC495
Formula: C7H6O2

Ingredient ID: TCMC2201
Formula: C8H10O2

Ingredient ID: TCMC2105
Formula: C18H36O2

Ingredient ID: TCMC1409
Formula: C21H20O12

Ingredient ID: TCMC1374
Formula: C6H12O6

Ingredient ID: TCMC1360
Formula: C33H40O15

Ingredient ID: TCMC1356
Formula: C21H20O12


Ingredient ID Formulae Name MW AlogP MlogP XlogP # HBA # HBD PSA # Rotatable Bond # Ring # Heacy Atom Lipinski RO5 Violation
TCMC495 C7H6O2 4-Hydroxybenzaldehyde 122.04 -0.6527 2.01 1.484 1 1 37.3 2 1 9 0
TCMC1356 C21H20O12 Hyperoside 464.1 -4.8921 2.45 -0.354 7 8 206.6 12 4 33 1
TCMC1360 C33H40O15 Icariin 676.24 -3.3928 3.44 1.764 11 8 234.29 21 5 48 2
TCMC1374 C6H12O6 Inositol 180.06 -3.0642 1.46 -1.458 6 6 121.38 6 1 12 1
TCMC1409 C21H20O12 Isoquercetin 464.1 -4.8921 2.45 -0.354 7 8 206.6 12 4 33 1
TCMC2105 C18H36O2 Stearic Acid 284.27 -4.4737 3.22 8.708 2 1 37.3 18 0 20 2
TCMC2201 C8H10O2 Tyrosol 138.07 -0.6534 2.12 1.171 1 2 40.46 4 1 10 0

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