Component: Castanea mollissima 板栗壳


Description of the Component

Component ID
TCMH128
Latin Name
Castanea mollissima
English Name
Chestnut shell
Chinese Pinyin Name
Ban Li Ke
中文名
板栗壳
TCM Properties
TCM Meridians
Therapeutic Class English
Therapeutic Class Chinese
Functions
Toxicity
NA
Geo-authentic habitats (道地产区)
NA
Reference
Chinese Pharmacopoeia (2015)
Barcode ID
GBVX1897-13
Barcode Source
BOLDSYSTEMS

TCM Prescriptions with the Component

Prescription ID Prescription English Name Prescription Chinese Name
TCMFx4917 Hua Tan Xiao Ke Tablets 化痰消咳片
TCMF78 Qing Re Zhen Ke Syrup 清热镇咳糖浆
TCMF5706 Qing Re Zhen Ke Syrup 清热镇咳糖浆

Targeted Human Proteins by the Ingredient of Component

Target ID Gene Symbol Target Name Target Class Uniprot ID
TCMT156 CYP19A1 Cytochrome P450 19A1 Oxidoreductase P11511
TCMT2 MAPT Microtubule-associated protein tau Unclassified P10636
TCMT215 CYP1A1 Cytochrome P450 1A1 Oxidoreductase P04798
TCMT219 CYP1A2 Cytochrome P450 1A2 Oxidoreductase P05177
TCMT257 CYP1B1 Cytochrome P450 1B1 Oxidoreductase Q16678
TCMT297 FABP4 Fatty acid binding protein adipocyte Unclassified P15090
TCMT298 FABP3 Fatty acid binding protein muscle Hydrolase P05413
TCMT3 ALOX15 Arachidonate 15-lipoxygenase Oxidoreductase P16050
TCMT327 TRPV1 Vanilloid receptor Ion channel Q8NER1
TCMT33 CYP3A4 Cytochrome P450 3A4 Oxidoreductase P08684
TCMT6 NFKB1 Nuclear factor NF-kappa-B p105 subunit Transcription factor P19838
TCMT63 PPARA Peroxisome proliferator-activated receptor alpha Nuclear receptor Q07869
TCMT64 PPARD Peroxisome proliferator-activated receptor delta Nuclear receptor Q03181
TCMT67 PPARG Peroxisome proliferator-activated receptor gamma Nuclear receptor P37231
TCMT8 KDM4E Lysine-specific demethylase 4D-like Oxidoreductase B2RXH2
TCMT808 FABP5 Fatty acid binding protein epidermal Unclassified Q01469
TCMT809 FABP2 Fatty acid binding protein intestinal Unclassified P12104
TCMT810 TLR2 Toll-like receptor 2 Unclassified O60603


Targeted Pathogenic Microbes by the Ingredient of Component

Target ID Target Name
TCMT1176 Streptococcus pneumoniae
TCMT1181 Mycobacterium tuberculosis H37Ra
TCMT1191 Bacillus megaterium
TCMT1214 Enterococcus faecium
TCMT1217 Bacillus anthracis
TCMT1218 Staphylococcus aureus
TCMT1229 Enterococcus faecalis
TCMT1236 Mycobacterium bovis
TCMT1246 Escherichia coli
TCMT1260 Streptococcus agalactiae
TCMT1286 Bacillus cereus
TCMT1319 Corynebacterium xerosis
TCMT1322 Streptococcus mitis
TCMT1323 Corynebacterium pseudodiphtheriticum
TCMT1324 Corynebacterium diphtheriae
TCMT1361 Neisseria meningitidis
TCMT1382 Plasmodium falciparum (isolate K1 / Thailand)
TCMT1410 Listeria monocytogenes
TCMT1439 Mycobacterium smegmatis
TCMT1442 Leishmania donovani
TCMT1454 Bacillus subtilis
TCMT1455 Mycobacterium tuberculosis H37Rv
TCMT1463 Mycobacterium tuberculosis
TCMT1465 Entamoeba histolytica

Ingredient Structrues

Ingredient ID: TCMC759
Formula: C22H44O2

Ingredient ID: TCMC426
Formula: C16H16O2

Ingredient ID: TCMC2777
Formula: C16H16O4

Ingredient ID: TCMC2357
Formula: C20H28O3

Ingredient ID: TCMC2207
Formula: CH4N2O

Ingredient ID: TCMC2105
Formula: C18H36O2

Ingredient ID: TCMC1901
Formula: C15H14O2

Ingredient ID: TCMC1898
Formula: C15H12O4

Ingredient ID: TCMC1830
Formula: C16H32O2

Ingredient ID: TCMC1100
Formula: C20H40O2

Properties

Ingredient ID Formulae Name MW AlogP MlogP XlogP # HBA # HBD PSA # Rotatable Bond # Ring # Heacy Atom Lipinski RO5 Violation
TCMC426 C16H16O2 3,5-O-Dimethylpinosylvin 240.12 0.3642 3 6.492 0 0 18.46 6 2 18 1
TCMC759 C22H44O2 Behenic Acid 340.33 -5.6257 3.66 10.984 2 1 37.3 22 0 24 2
TCMC1100 C20H40O2 Elcosanoic Acid 312.3 -5.0497 3.44 9.846 2 1 37.3 20 0 22 2
TCMC1830 C16H32O2 Palmitic Acid 256.24 -3.8977 3 7.57 2 1 37.3 16 0 18 2
TCMC1898 C15H12O4 Pinocembrin 256.07 -1.3541 2.67 2.493 1 2 66.76 3 3 19 0
TCMC1901 C15H14O2 Pinosylvin Methyl Ether 226.1 -0.0443 2.89 5.973 0 1 29.46 5 2 17 1
TCMC2105 C18H36O2 Stearic Acid 284.27 -4.4737 3.22 8.708 2 1 37.3 18 0 20 2
TCMC2207 CH4N2O Urea 60.03 -0.0745 1.24 -0.235 3 3 70.1 2 0 4 0
TCMC2357 C20H28O3 15-Hydroxydehydroabietic Acid 316.2 0.4623 3.33 5.77 3 2 57.53 8 3 23 1
TCMC2777 C16H16O4 Vestitol 272.1 -1.0998 2.78 2.326 0 2 58.92 5 3 20 0

Download Data

All data can be downloaded by:

   → Selecting data type in the below download table
   → Then click the download button.
Data Section
Select to Download
1. General Information of the Component  
2. TCM Prescriptions with the Component  
3. Putative Targets  
4. Activity & References for Filtering Putative Targets  
5. Ingredient Data & Chemical Structure Information (Properties, InChI, InChIkey, SMILES, etc.)