Component: Piper sarmentosum 假蒟叶


Description of the Component

Component ID
TCMH1051
Latin Name
Piper sarmentosum
English Name
Sarmentose pepper
Chinese Pinyin Name
Jia 蒟ye
中文名
假蒟叶
TCM Properties
TCM Meridians
Therapeutic Class English
Therapeutic Class Chinese
Functions
Toxicity
NA
Geo-authentic habitats (道地产区)
NA
Reference
SATCM
Barcode ID
GBVY2651-14, GBVP7053-15
Barcode Source
BOLDSYSTEMS

TCM Prescriptions with the Component

Prescription ID Prescription English Name Prescription Chinese Name

Targeted Human Proteins by the Ingredient of Component

Target ID Gene Symbol Target Name Target Class Uniprot ID
TCMT100 TTR Transthyretin Unclassified P02766
TCMT114 CNR2 Cannabinoid CB2 receptor GPCR P34972
TCMT133 CA1 Carbonic anhydrase I Lyase P00915
TCMT134 CA2 Carbonic anhydrase II Lyase P00918
TCMT137 CA9 Carbonic anhydrase IX Lyase Q16790
TCMT141 CA5A Carbonic anhydrase VA Lyase P35218
TCMT142 CA4 Carbonic anhydrase IV Lyase P22748
TCMT156 CYP19A1 Cytochrome P450 19A1 Oxidoreductase P11511
TCMT160 HTR7 Serotonin 7 (5-HT7) receptor GPCR P34969
TCMT161 HCAR2 Hydroxycarboxylic acid receptor 2 GPCR Q8TDS4
TCMT215 CYP1A1 Cytochrome P450 1A1 Oxidoreductase P04798
TCMT219 CYP1A2 Cytochrome P450 1A2 Oxidoreductase P05177
TCMT223 AKR1B1 Aldose reductase Oxidoreductase P15121
TCMT257 CYP1B1 Cytochrome P450 1B1 Oxidoreductase Q16678
TCMT281 DPP4 Dipeptidyl peptidase IV Unclassified P27487
TCMT302 HMGCR HMG-CoA reductase Oxidoreductase P04035
TCMT33 CYP3A4 Cytochrome P450 3A4 Oxidoreductase P08684
TCMT34 CYP2D6 Cytochrome P450 2D6 Oxidoreductase P10635
TCMT41 IDH1 Isocitrate dehydrogenase [NADP] cytoplasmic Oxidoreductase O75874
TCMT45 APP Beta amyloid A4 protein Unclassified P05067
TCMT588 DAO D-amino-acid oxidase Oxidoreductase P14920
TCMT654 GRM5 Metabotropic glutamate receptor 5 GPCR P41594
TCMT67 PPARG Peroxisome proliferator-activated receptor gamma Nuclear receptor P37231
TCMT82 ESR1 Estrogen receptor alpha Nuclear receptor P03372
TCMT87 CYP2C9 Cytochrome P450 2C9 Oxidoreductase P11712


Targeted Pathogenic Microbes by the Ingredient of Component

Target ID Target Name
TCMT1181 Mycobacterium tuberculosis H37Ra
TCMT1218 Staphylococcus aureus
TCMT1251 Candida albicans
TCMT1294 Human parainfluenza virus 3
TCMT1438 Plasmodium falciparum
TCMT1454 Bacillus subtilis
TCMT1455 Mycobacterium tuberculosis H37Rv
TCMT1463 Mycobacterium tuberculosis
TCMT1465 Entamoeba histolytica

Ingredient Structrues

Ingredient ID: TCMC916
Formula: C9H8O2

Ingredient ID: TCMC801
Formula: C29H50O

Ingredient ID: TCMC770
Formula: C7H6O2

Ingredient ID: TCMC2716
Formula: C26H37NO3

Ingredient ID: TCMC2597
Formula: C14H23NO

Ingredient ID: TCMC2507
Formula: C20H25NO3

Ingredient ID: TCMC2461
Formula: C18H21NO3

Ingredient ID: TCMC2403
Formula: C29H24O6

Ingredient ID: TCMC2372
Formula: C20H23NO3

Ingredient ID: TCMC2180
Formula: C12H16O3

Ingredient ID: TCMC2107
Formula: C29H48O

Ingredient ID: TCMC2088
Formula: C7H6O2.Na

Ingredient ID: TCMC2066
Formula: C20H18O6

Ingredient ID: TCMC1898
Formula: C15H12O4

Ingredient ID: TCMC1848
Formula: C14H25NO

Ingredient ID: TCMC1745
Formula: C16H29NO

Ingredient ID: TCMC1299
Formula: C24H33NO3

Ingredient ID: TCMC1101
Formula: C11H12O3

Properties

Ingredient ID Formulae Name MW AlogP MlogP XlogP # HBA # HBD PSA # Rotatable Bond # Ring # Heacy Atom Lipinski RO5 Violation
TCMC770 C7H6O2 Benzoic Acid 122.04 -0.2398 2.01 2.666 2 1 37.3 2 1 9 0
TCMC801 C29H50O Beta-Sitosterol 414.39 1.3 4.54 11.595 1 1 20.23 13 4 30 1
TCMC916 C9H8O2 Cinnamic Acid 148.05 0.1213 2.23 3.904 2 1 37.3 3 1 11 0
TCMC1101 C11H12O3 Elemicin 192.08 0.6742 2.34 2.486 0 0 27.69 4 2 14 0
TCMC1299 C24H33NO3 Guineensine 383.25 0.6319 3.66 7.693 2 1 51.05 15 2 28 2
TCMC1745 C16H29NO N-Isobutyl-(2E,4E)-Dodecadienamide 251.22 -0.0255 3 6.025 2 1 32.59 14 0 18 1
TCMC1848 C14H25NO Pellitorin 223.19 0.5505 2.78 4.887 2 1 32.59 12 0 16 0
TCMC1898 C15H12O4 Pinocembrin 256.07 -1.3541 2.67 2.493 1 2 66.76 3 3 19 0
TCMC2066 C20H18O6 Sesamin 354.11 -1.6034 3 2.576 2 0 55.38 2 6 26 0
TCMC2088 C7H6O2.Na Sodium Benzoate 121.03 -0.9176 2.01 2.185 2 0 40.13 2 1 9 0
TCMC2107 C29H48O Stigmasterol 412.37 1.2566 4.54 11.071 1 1 20.23 12 4 30 1
TCMC2180 C12H16O3 Trans-Asarone 208.11 0.7519 2.45 2.669 0 0 27.69 8 1 15 0
TCMC2372 C20H23NO3 9-(Benzo[D][1,3]Dioxol-5-Yl)-1-(Pyrrolidin-1-Yl)Nona-2,4,8-Trien-1-One 325.17 0.3176 3.22 4.569 2 0 38.77 7 3 24 0
TCMC2403 C29H24O6 Dichamanetin 468.16 -1.3623 3.99 5.633 1 4 107.22 9 5 35 1
TCMC2461 C18H21NO3 Sarmentosine 299.15 -0.1502 3 3.875 2 0 38.77 6 3 22 0
TCMC2507 C20H25NO3 Brachyamide B 327.18 -0.7262 3.22 5.013 2 0 38.77 8 3 24 1
TCMC2597 C14H23NO Sarmentine 221.18 -0.9158 2.78 4.039 2 0 20.31 8 1 16 0
TCMC2716 C26H37NO3 Brachystamide B 411.28 0.0559 3.88 8.831 2 1 51.05 17 2 30 2

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