Component: Radix smilacis 铁丝威灵仙

Description of the Component

Component ID
Latin Name
Radix smilacis
English Name
root and rhizome of smilax
Chinese Pinyin Name
Tie Si Wei Ling Xian
TCM Properties
TCM Meridians
Therapeutic Class English
Therapeutic Class Chinese
Geo-authentic habitats (道地产区)
Chinese Pharmacopoeia (2015)
Barcode ID
Barcode Source

TCM Prescriptions with the Component

Prescription ID Prescription English Name Prescription Chinese Name
TCMF3399 Feng Shi Guan Jie Wine 风湿关节酒
TCMF3548 Feng Shi Zhen Tong Pills 风湿镇痛丸
TCMF3598 Feng Tong Pills 风痛丸
TCMF6924 Fu Fang Yu Gan Zi Li Yan Tablets 复方余甘子利咽片
TCMF1450 Goupi Plaster 狗皮膏
TCMF2631 Goupi Plaster, Dog-skin Plaster 狗皮膏
TCMF3442 Gu Ci Xiao Tong Oral Liquid 骨刺消痛液
TCMFx4688 Hu Gu Mu Gua Pills 虎骨木瓜丸
TCMF3996 Huan Gu Pills 换骨丸
TCMFx4325 Huo Luo Pills 活络丸
TCMF4284 Jin Gu Ning Cha Ji 筋骨宁搽剂
TCMF4601 Pian Tan Fu Yuan Pills 偏瘫复元丸
TCMFx4629 Ping Gan Shu Luo Pills 平肝舒络丸
TCMFx80 Qing Xuan Zhi Tan Pills 清眩治瘫丸
TCMFx5864 Qing Xuan Zhi Tan Pills 清眩治瘫丸
TCMFx5703 Shang Ke Zhuang Gu Ointment 伤科壮骨膏
TCMFx5051 Tong Ren Da Huo Luo Pills 同仁大活络丸
TCMFx6320 Xiao Shuan Zai Zao Pills 消栓再造丸
TCMFx382 Xin Nao Jing Tablet 心脑静片
TCMFx6836 Xin Nao Jing Tablets 心脑静片
TCMFx6031 Yang Xue Rong Jin Pills 养血荣筋丸
TCMFx837 Yang Xue Rong Jin Pills 养血荣筋丸
TCMF6686 Zhui Feng Zhuang Gu Ointment 追风壮骨膏

Targeted Human Proteins by the Ingredient of Component

Target ID Gene Symbol Target Name Target Class Uniprot ID
TCMT150 RORC Nuclear receptor ROR-gamma Nuclear receptor P51449
TCMT162 UGT1A1 UDP-glucuronosyltransferase 1-1 Transferase P22309
TCMT3 ALOX15 Arachidonate 15-lipoxygenase Oxidoreductase P16050
TCMT33 CYP3A4 Cytochrome P450 3A4 Oxidoreductase P08684
TCMT63 PPARA Peroxisome proliferator-activated receptor alpha Nuclear receptor Q07869
TCMT64 PPARD Peroxisome proliferator-activated receptor delta Nuclear receptor Q03181
TCMT67 PPARG Peroxisome proliferator-activated receptor gamma Nuclear receptor P37231
TCMT8 KDM4E Lysine-specific demethylase 4D-like Oxidoreductase B2RXH2

Targeted Pathogenic Microbes by the Ingredient of Component

Target ID Target Name
TCMT1178 Actinomyces viscosus
TCMT1209 Staphylococcus haemolyticus
TCMT1210 Streptococcus sobrinus
TCMT1211 Fusobacterium nucleatum
TCMT1218 Staphylococcus aureus
TCMT1223 Staphylococcus epidermidis
TCMT1226 Klebsiella pneumoniae
TCMT1229 Enterococcus faecalis
TCMT1245 Phytophthora cactorum
TCMT1246 Escherichia coli
TCMT1251 Candida albicans
TCMT1253 Penicillium chrysogenum
TCMT1321 Staphylococcus hominis
TCMT1343 Staphylococcus simulans
TCMT1344 Staphylococcus sciuri
TCMT1370 Prevotella melaninogenica
TCMT1408 Colletotrichum gloeosporioides
TCMT1448 Enterobacter aerogenes
TCMT1454 Bacillus subtilis
TCMT1462 Streptococcus mutans

Ingredient Structrues

Ingredient ID: TCMC999
Formula: C10H20O2

Ingredient ID: TCMC696
Formula: C10H12O

Ingredient ID: TCMC463
Formula: C14H12N2S

Ingredient ID: TCMC2541
Formula: C10H18O

Ingredient ID: TCMC2166
Formula: C10H14O

Ingredient ID: TCMC1777
Formula: C8H18O

Ingredient ID: TCMC1578
Formula: C11H14O2

Ingredient ID: TCMC1493
Formula: C10H18O

Ingredient ID: TCMC1101
Formula: C11H12O3


Ingredient ID Formulae Name MW AlogP MlogP XlogP # HBA # HBD PSA # Rotatable Bond # Ring # Heacy Atom Lipinski RO5 Violation
TCMC463 C14H12N2S 4-(1,3-Benzothiazol-2-Yl)-2-Methylaniline 240.07 0.4827 2.67 3.571 2 1 67.15 3 3 17 0
TCMC696 C10H12O Anethole 148.09 0.8555 2.45 3.979 0 0 9.23 4 1 11 0
TCMC999 C10H20O2 Decanoic Acid 172.15 -2.1697 2.34 4.156 2 1 37.3 10 0 12 0
TCMC1101 C11H12O3 Elemicin 192.08 0.6742 2.34 2.486 0 0 27.69 4 2 14 0
TCMC1493 C10H18O Linalool (+) 154.14 2.4692 2.45 2.468 1 1 20.23 8 0 11 0
TCMC1578 C11H14O2 Methyleugenol 178.1 0.9251 2.45 3.003 0 0 18.46 6 1 13 0
TCMC1777 C8H18O Octanol 130.14 -2.1254 2.23 3.127 1 1 20.23 8 0 9 0
TCMC2166 C10H14O Thymol 150.1 0.7546 2.45 3.556 0 1 20.23 5 1 11 0
TCMC2541 C10H18O Alpha-Terpineol 154.14 1.1223 2.45 2.369 1 1 20.23 5 1 11 0

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1. General Information of the Component  
2. TCM Prescriptions with the Component  
3. Putative Targets  
4. Activity & References for Filtering Putative Targets  
5. Ingredient Data & Chemical Structure Information (Properties, InChI, InChIkey, SMILES, etc.)