| GO Term |
GO Name |
Enriched Genes |
Log10 Adjusted P-value |
|
[BP] GO:0065008 |
regulation of biological quality
|
ABCB1, ABCG2, ACHE, ADORA1, ADRA1A, ADRB1, AKR1B1, APEX1, APP, AR, AURKB, AXL, BCL2, CA12, CA2, CA7, CACNA1C, CDK6, CYP19A1, CYP1A1, CYP1B1, DRD1, DRD2, DRD3, DRD5, EGFR, ESR1, F3, FABP3, FABP4, FLT3, GAA, GBA, GPER1, GPR35, HCAR2, HIF1A, HSD11B1, HSD11B2, HSD17B1, HSD17B2, HSPA1A, HTR1A, HTR2A, HTR2B, HTR7, INSR, KDR, MET, MIF, PIK3CA, PIK3CB, POLA1, POLB, PPARA, PRKCA, PRKCB, PRKCD, PRKCE, PTGS1, PTGS2, SLC22A1, SLC22A2, SLC22A3, SMAD3, SRC, TEK, TERT, TNKS, TNKS2, TRPV1, XDH |
17.8977 |
|
[BP] GO:0042221 |
response to chemical
|
ABCB1, ABCG2, ADRA1A, AKR1B1, ALPL, APEX1, APP, AR, AXL, BCL2, CA2, CA3, CA9, CDK6, CSNK2A1, CYP1A1, CYP1A2, CYP1B1, DNMT1, DRD1, DRD2, DRD3, DRD5, EGFR, ERBB2, ESR1, ESRRA, FABP3, FABP4, FLT3, GBA, GPER1, HIF1A, HSD11B2, HSD17B2, HSPA1A, HTR2A, HTR2B, HTR5A, IDO1, IGF1R, INSR, KDR, MMP2, MMP9, NR3C1, PIK3CA, POLB, PPARA, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, PTGS2, RORC, SMAD3, SRC, TEK, TERT, TRPV1, TYR |
17.591 |
|
[BP] GO:0010033 |
response to organic substance
|
ADRA1A, AKR1B1, ALPL, APEX1, APP, AR, AXL, BCL2, CA2, CA3, CA9, CDK6, CSNK2A1, CYP1A1, CYP1A2, CYP1B1, DNMT1, DRD1, DRD2, DRD3, DRD5, EGFR, ERBB2, ESR1, ESRRA, FABP3, FABP4, FLT3, GBA, GPER1, HIF1A, HSD11B2, HSD17B2, HSPA1A, HTR5A, IDO1, IGF1R, INSR, KDR, MMP2, NR3C1, PIK3CA, POLB, PPARA, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, PTGS2, RORC, SMAD3, SRC, TEK, TRPV1, TYR |
17.591 |
|
[BP] GO:1901700 |
response to oxygen-containing compound
|
AKR1B1, ALPL, APEX1, APP, AR, AXL, BCL2, CA3, CA9, CDK6, CSNK2A1, CYP1A1, CYP1A2, CYP1B1, DNMT1, DRD1, DRD2, DRD3, DRD5, EGFR, ESR1, ESRRA, FABP3, GBA, GPER1, HSD11B2, HSD17B2, HTR5A, IDO1, IGF1R, INSR, MMP2, MMP9, NR3C1, PIK3CA, POLB, PPARA, PRKCB, PRKCD, PRKCE, PTGS2, RORC, SRC, TEK, TRPV1, TYR |
17.591 |
|
[BP] GO:0010647 |
positive regulation of cell communication
|
ADORA1, ADRA1A, ADRB1, AKR1B1, APP, AR, AXL, BCL2, CA2, CA7, CSNK2A1, CYP19A1, CYP1B1, DRD1, DRD2, DRD3, EGFR, ERBB2, F3, FLT3, GBA, GPER1, GPR35, HCAR2, HIF1A, HSPA1A, HTR2A, HTR2B, HTR6, INSR, KDR, MET, MIF, MMP12, MMP9, PIK3CA, PIK3CB, PRKCA, PRKCB, PRKCD, PRKCE, PTGS2, PTPN1, SMAD3, SRC, TEK, TERT, TNKS, TNKS2, XDH |
16.5924 |
|
[BP] GO:0023056 |
positive regulation of signaling
|
ADORA1, ADRA1A, ADRB1, AKR1B1, APP, AR, AXL, BCL2, CA2, CA7, CSNK2A1, CYP19A1, CYP1B1, DRD1, DRD2, DRD3, EGFR, ERBB2, F3, FLT3, GBA, GPER1, GPR35, HCAR2, HIF1A, HSPA1A, HTR2A, HTR2B, HTR6, INSR, KDR, MET, MIF, MMP12, MMP9, PIK3CA, PIK3CB, PRKCA, PRKCB, PRKCD, PRKCE, PTGS2, PTPN1, SMAD3, SRC, TEK, TERT, TNKS, TNKS2, XDH |
16.5639 |
|
[BP] GO:0008152 |
metabolic process
|
ABCG2, ACHE, ADORA1, ADRB1, AKR1B1, AKR1B10, ALDH2, ALOX5, ALPI, ALPL, AOX1, APEX1, APP, AR, AURKB, AXL, BACE1, BCL2, CA1, CA12, CA2, CA3, CA4, CA5A, CA5B, CA6, CA7, CA9, CDC25B, CDK6, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, CYP2D6, DAO, DNMT1, DRD1, DRD2, DRD3, DRD5, DUSP3, DYRK1A, EGFR, ERBB2, ESR1, ESR2, ESRRA, ESRRB, F3, FABP3, FABP4, FLT3, FUCA1, FUT7, GAA, GBA, GBA2, GLO1, HIF1A, HSD11B1, HSD11B2, HSD17B1, HSD17B2, HSPA1A, HTR1A, HTR2B, IDO1, IGF1R, INSR, KDR, MET, MGAM, MIF, MMP1, MMP12, MMP2, MMP9, NQO2, NR3C1, NR3C2, NUAK1, PGR, PIK3CA, PIK3CB, PIM1, POLA1, POLB, PPARA, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, PTGS1, PTGS2, PTPN1, RORC, SLC22A2, SMAD3, SRC, TBXAS1, TEK, TERT, TNKS, TNKS2, TOP2A, TRPV1, TYR, XDH |
13.7503 |
|
[BP] GO:0042127 |
regulation of cell proliferation
|
ADORA1, ADORA3, ADRA1A, AKR1B1, APP, AR, BCL2, CDC25B, CDK6, CSNK2A1, CYP1B1, DNMT1, DRD2, DRD3, EGFR, ERBB2, ESR1, ESRRA, F3, FABP3, FLT3, GPER1, HIF1A, HSPA1A, HTR1A, HTR2A, HTR2B, IDO1, IGF1R, INSR, KDR, MIF, MMP12, MMP2, MMP9, NUAK1, PGR, PIM1, PRKCA, PTGS1, PTGS2, SMAD3, SRC, TEK, TERT, XDH |
13.7314 |
|
[BP] GO:0014070 |
response to organic cyclic compound
|
ALPL, APEX1, APP, AR, BCL2, CA2, CA9, CSNK2A1, CYP1A1, CYP1A2, CYP1B1, DRD1, DRD2, DRD3, DRD5, EGFR, ESR1, ESRRA, FLT3, GBA, GPER1, HSD11B2, HTR5A, NR3C1, PRKCE, PRKCG, PTGS2, RORC, SRC, TEK, TRPV1, TYR |
13.7007 |
|
[BP] GO:0009967 |
positive regulation of signal transduction
|
ADORA1, ADRA1A, ADRB1, AKR1B1, APP, AR, AXL, BCL2, CSNK2A1, CYP1B1, DRD2, DRD3, EGFR, ERBB2, F3, FLT3, GPER1, GPR35, HIF1A, HSPA1A, HTR2A, HTR2B, HTR6, INSR, KDR, MET, MIF, MMP12, MMP9, PIK3CA, PIK3CB, PRKCA, PRKCB, PRKCD, PRKCE, PTGS2, PTPN1, SMAD3, SRC, TEK, TERT, TNKS, TNKS2, XDH |
13.4807 |
|
[BP] GO:0009719 |
response to endogenous stimulus
|
ADRA1A, AKR1B1, ALPL, APEX1, APP, AR, BCL2, CA2, CA9, CSNK2A1, CYP1A2, DNMT1, DRD1, DRD5, EGFR, ERBB2, ESR1, ESRRA, FABP3, FLT3, GBA, GPER1, HSD11B2, HTR5A, IGF1R, INSR, MMP2, NR3C1, PPARA, PRKCD, PRKCE, PTGS2, SMAD3, SRC, TEK, TRPV1 |
13.3573 |
|
[BP] GO:0042592 |
homeostatic process
|
ABCG2, ADORA1, ADRA1A, ADRB1, AKR1B1, APEX1, APP, AXL, BCL2, CA12, CA2, CA7, CACNA1C, DRD1, DRD2, DRD3, DRD5, EGFR, ESR1, FABP3, FABP4, FLT3, GAA, GBA, GPER1, GPR35, HIF1A, HTR2A, HTR2B, INSR, MET, PIK3CA, PIK3CB, POLA1, POLB, PRKCB, PRKCE, SMAD3, SRC, TERT, TRPV1 |
12.8377 |
|
[BP] GO:0042493 |
response to drug
|
ABCB1, ABCG2, ADRA1A, AKR1B1, APEX1, AXL, BCL2, CA3, CA9, CDK6, CYP1A1, CYP1B1, DRD1, DRD2, DRD3, DRD5, EGFR, FABP3, GBA, HSD11B2, HTR2A, HTR2B, KDR, NR3C1, POLB, PRKCD, PRKCE, PRKCG, PTGS2, SRC, TRPV1 |
12.7063 |
|
[BP] GO:0048522 |
positive regulation of cellular process
|
ACHE, ADORA1, ADRA1A, ADRB1, AKR1B1, APEX1, APP, AR, AURKB, AXL, BCL2, CA2, CA7, CDC25B, CDK6, CSNK2A1, CYP19A1, CYP1A1, CYP1B1, DNMT1, DRD1, DRD2, DRD3, DRD5, DUSP3, DYRK1A, EGFR, ERBB2, ESR1, ESR2, ESRRA, ESRRB, F3, FABP3, FLT3, GBA, GPER1, GPR35, HCAR2, HIF1A, HSPA1A, HTR1A, HTR2A, HTR2B, HTR6, IDO1, IGF1R, INSR, KDR, MET, MIF, MMP1, MMP12, MMP2, MMP9, NR3C1, PGR, PIK3CA, PIK3CB, PIM1, PPARA, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, PTGS2, PTPN1, RORC, SMAD3, SRC, TEK, TERT, TNKS, TNKS2, TOP2A, TRPV1, XDH |
12.4021 |
|
[BP] GO:0044281 |
small molecule metabolic process
|
ABCG2, AKR1B1, AKR1B10, ALDH2, ALOX5, AOX1, APP, CA1, CA12, CA2, CA3, CA4, CA5A, CA5B, CA6, CA7, CA9, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, CYP2D6, DAO, FABP3, FUCA1, FUT7, GAA, GBA, GBA2, GLO1, HIF1A, HSPA1A, HTR2B, IDO1, MIF, PIK3CA, PIM1, PPARA, PTGS1, PTGS2, TBXAS1, TYR, XDH |
12.3444 |
|
[BP] GO:0006629 |
lipid metabolic process
|
ACHE, ADORA1, AKR1B1, AKR1B10, ALOX5, ALPI, APP, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, CYP2D6, DRD2, EGFR, ERBB2, ESR1, FABP3, FABP4, FUCA1, FUT7, GBA, GBA2, HSD11B1, HSD11B2, HSD17B1, HSD17B2, MET, MIF, PIK3CA, PIK3CB, PPARA, PTGS1, PTGS2, TBXAS1, TRPV1 |
12.2833 |
|
[BP] GO:1902531 |
regulation of intracellular signal transduction
|
ADORA1, ADRA1A, ADRB1, AKR1B1, APP, AR, AURKB, AXL, BCL2, CSNK2A1, CYP1B1, DRD2, DRD3, DUSP3, DYRK1A, EGFR, ERBB2, ESR1, F3, FLT3, GBA, GPER1, GPR35, HIF1A, HSPA1A, HTR2A, HTR2B, HTR6, IGF1R, INSR, KDR, MET, MIF, MMP9, NUAK1, PIK3CA, PIK3CB, PRKCA, PRKCB, PRKCD, PRKCE, PTGS2, PTPN1, SRC, TEK, XDH |
12.1683 |
|
[BP] GO:0032844 |
regulation of homeostatic process
|
ADORA1, AURKB, BCL2, CA2, CA7, CACNA1C, CDK6, DRD1, DRD2, DRD3, EGFR, GPER1, HCAR2, HIF1A, HTR2A, HTR2B, KDR, MIF, PIK3CB, PRKCE, PTGS2, SRC, TNKS, TNKS2, TRPV1 |
11.9145 |
|
[BP] GO:1902533 |
positive regulation of intracellular signal transduction
|
ADORA1, ADRA1A, ADRB1, AKR1B1, APP, AR, AXL, BCL2, CYP1B1, DRD2, EGFR, ERBB2, F3, FLT3, GPER1, GPR35, HSPA1A, HTR2A, HTR2B, HTR6, INSR, KDR, MET, MIF, PIK3CA, PIK3CB, PRKCA, PRKCB, PRKCE, PTGS2, PTPN1, SRC, TEK, XDH |
11.9145 |
|
[BP] GO:0044237 |
cellular metabolic process
|
ABCG2, ACHE, AKR1B1, AKR1B10, ALDH2, ALOX5, ALPI, ALPL, AOX1, APEX1, APP, AR, AURKB, AXL, BACE1, BCL2, CA1, CA12, CA2, CA3, CA4, CA5A, CA5B, CA6, CA7, CA9, CDC25B, CDK6, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, CYP2D6, DAO, DNMT1, DRD1, DRD2, DRD3, DRD5, DUSP3, DYRK1A, EGFR, ERBB2, ESR1, ESR2, ESRRA, ESRRB, FABP3, FABP4, FLT3, FUCA1, FUT7, GAA, GBA, GBA2, GLO1, HIF1A, HSD17B1, HSD17B2, HSPA1A, HTR1A, HTR2B, IDO1, IGF1R, INSR, KDR, MET, MGAM, MIF, MMP1, MMP2, NQO2, NR3C1, NR3C2, NUAK1, PGR, PIK3CA, PIK3CB, PIM1, POLA1, POLB, PPARA, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, PTGS1, PTGS2, PTPN1, RORC, SLC22A2, SMAD3, SRC, TBXAS1, TEK, TERT, TNKS, TNKS2, TOP2A, TYR, XDH |
11.8934 |
|
[BP] GO:0010941 |
regulation of cell death
|
ADORA1, AKR1B1, APEX1, AR, AURKB, AXL, BCL2, CSNK2A1, CYP1B1, EGFR, ESR1, F3, FLT3, GBA, GLO1, GPER1, HCAR2, HIF1A, HSPA1A, HTR2B, IDO1, IGF1R, KDR, MET, MIF, MMP9, PIK3CA, PIK3CB, PIM1, PPARA, PRKCA, PRKCD, PRKCG, PTGS2, PTPN1, SIGMAR1, SMAD3, SRC, TEK, TERT, TOP2A, TRPV1, XDH |
11.6909 |
|
[BP] GO:0010646 |
regulation of cell communication
|
ACHE, ADORA1, ADRA1A, ADRB1, AKR1B1, APP, AR, AURKB, AXL, BACE1, BCL2, CA2, CA7, CACNA1C, CSNK2A1, CYP19A1, CYP1B1, DRD1, DRD2, DRD3, DRD5, DUSP3, DYRK1A, EGFR, ERBB2, ESR1, ESR2, F3, FLT3, GBA, GPER1, GPR35, HCAR2, HIF1A, HSPA1A, HTR1A, HTR2A, HTR2B, HTR6, IGF1R, INSR, KDR, MET, MIF, MMP12, MMP9, NUAK1, PIK3CA, PIK3CB, PRKCA, PRKCB, PRKCD, PRKCE, PTGS2, PTPN1, SMAD3, SRC, TEK, TERT, TNKS, TNKS2, XDH |
11.6329 |
|
[BP] GO:0009725 |
response to hormone
|
ADRA1A, AKR1B1, ALPL, APEX1, AR, BCL2, CA2, CA9, CSNK2A1, CYP1A2, EGFR, ESR1, ESRRA, FABP3, FLT3, GBA, GPER1, HSD11B2, HTR5A, INSR, NR3C1, PPARA, PRKCD, PRKCE, PTGS2, SRC, TEK, TRPV1 |
11.4462 |
|
[BP] GO:0048584 |
positive regulation of response to stimulus
|
ADORA1, ADRA1A, ADRB1, AKR1B1, APP, AR, AXL, BCL2, CSNK2A1, CYP1B1, DRD2, DRD3, EGFR, ERBB2, ESRRA, F3, FABP4, FLT3, GPER1, GPR35, HIF1A, HSPA1A, HTR2A, HTR2B, HTR6, IDO1, INSR, KDR, MET, MIF, MMP12, MMP2, MMP9, PIK3CA, PIK3CB, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, PTGS2, PTPN1, SMAD3, SRC, TEK, TERT, TNKS, TNKS2, XDH |
11.446 |
|
[BP] GO:0043067 |
regulation of programmed cell death
|
ADORA1, AKR1B1, APEX1, AR, AURKB, AXL, BCL2, CSNK2A1, CYP1B1, EGFR, ESR1, F3, FLT3, GLO1, GPER1, HCAR2, HIF1A, HSPA1A, HTR2B, IDO1, IGF1R, KDR, MET, MIF, MMP9, PIK3CA, PIK3CB, PIM1, PRKCA, PRKCD, PRKCG, PTGS2, PTPN1, SIGMAR1, SMAD3, SRC, TEK, TERT, TOP2A, TRPV1, XDH |
11.446 |
|
[BP] GO:0023051 |
regulation of signaling
|
ACHE, ADORA1, ADRA1A, ADRB1, AKR1B1, APP, AR, AURKB, AXL, BACE1, BCL2, CA2, CA7, CACNA1C, CSNK2A1, CYP19A1, CYP1B1, DRD1, DRD2, DRD3, DRD5, DUSP3, DYRK1A, EGFR, ERBB2, ESR1, ESR2, F3, FLT3, GBA, GPER1, GPR35, HCAR2, HIF1A, HSPA1A, HTR1A, HTR2A, HTR2B, HTR6, IGF1R, INSR, KDR, MET, MIF, MMP12, MMP9, NUAK1, PIK3CA, PIK3CB, PRKCA, PRKCB, PRKCD, PRKCE, PTGS2, PTPN1, SMAD3, SRC, TEK, TERT, TNKS, TNKS2, XDH |
11.446 |
|
[BP] GO:0015701 |
bicarbonate transport
|
CA1, CA12, CA14, CA2, CA3, CA4, CA5A, CA5B, CA6, CA7, CA9 |
11.446 |
|
[BP] GO:0051173 |
positive regulation of nitrogen compound metabolic process
|
ADORA1, ADRA1A, ADRB1, APP, AR, AURKB, BCL2, CDC25B, CSNK2A1, DNMT1, DRD1, DRD2, DRD3, DRD5, DYRK1A, EGFR, ERBB2, ESR1, ESR2, ESRRA, ESRRB, F3, FLT3, GBA, GPER1, HIF1A, HSPA1A, HTR2A, HTR2B, IGF1R, INSR, KDR, MET, MIF, MMP12, MMP9, NR3C1, PGR, PIK3CA, PIK3CB, PPARA, PRKCA, PRKCD, PRKCE, PRKCG, PTGS2, PTPN1, RORC, SMAD3, SRC, TEK, TERT, TNKS, TNKS2, TOP2A, TRPV1, XDH |
11.3711 |
|
[BP] GO:0010562 |
positive regulation of phosphorus metabolic process
|
ADORA1, ADRA1A, ADRB1, APP, AR, BCL2, CDC25B, DRD1, DRD2, DRD5, EGFR, ERBB2, ESRRB, FABP3, FLT3, GBA, GPER1, HIF1A, HTR2A, HTR2B, INSR, KDR, MIF, MMP9, PIK3CA, PIK3CB, PRKCA, PRKCD, PRKCE, PTGS2, PTPN1, SMAD3, SRC, TEK, XDH |
11.3607 |
|
[BP] GO:0045937 |
positive regulation of phosphate metabolic process
|
ADORA1, ADRA1A, ADRB1, APP, AR, BCL2, CDC25B, DRD1, DRD2, DRD5, EGFR, ERBB2, ESRRB, FABP3, FLT3, GBA, GPER1, HIF1A, HTR2A, HTR2B, INSR, KDR, MIF, MMP9, PIK3CA, PIK3CB, PRKCA, PRKCD, PRKCE, PTGS2, PTPN1, SMAD3, SRC, TEK, XDH |
11.3607 |
|
[BP] GO:0042981 |
regulation of apoptotic process
|
ADORA1, AKR1B1, APEX1, AR, AURKB, AXL, BCL2, CSNK2A1, CYP1B1, EGFR, ESR1, F3, FLT3, GLO1, GPER1, HCAR2, HIF1A, HSPA1A, HTR2B, IDO1, IGF1R, KDR, MIF, MMP9, PIK3CA, PIK3CB, PIM1, PRKCA, PRKCD, PRKCG, PTGS2, PTPN1, SIGMAR1, SMAD3, SRC, TEK, TERT, TOP2A, TRPV1, XDH |
10.9404 |
|
[BP] GO:0050896 |
response to stimulus
|
ABCB1, ABCG2, ACHE, ADORA1, ADORA3, ADRA1A, ADRB1, AKR1B1, ALPL, APEX1, APP, AR, AURKB, AXL, BCL2, CA2, CA3, CA6, CA9, CDK6, CSNK2A1, CYP1A1, CYP1A2, CYP1B1, DNMT1, DRD1, DRD2, DRD3, DRD5, EGFR, ERBB2, ESR1, ESRRA, F3, FABP3, FABP4, FLT3, GBA, GPER1, HIF1A, HSD11B2, HSD17B2, HSPA1A, HTR1A, HTR2A, HTR2B, HTR5A, IDO1, IGF1R, INSR, KDR, MIF, MMP12, MMP2, MMP9, NR3C1, NUAK1, PIK3CA, PIK3CB, POLA1, POLB, PPARA, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, PTGS1, PTGS2, PTPN1, RORC, SMAD3, SRC, TEK, TERT, TOP2A, TRPV1, TYR |
10.8509 |
|
[BP] GO:0006730 |
one-carbon metabolic process
|
CA1, CA12, CA2, CA3, CA4, CA5A, CA5B, CA6, CA7, CA9 |
10.7933 |
|
[BP] GO:0048518 |
positive regulation of biological process
|
ABCB1, ACHE, ADORA1, ADRA1A, ADRB1, AKR1B1, APEX1, APP, AR, AURKB, AXL, BCL2, CA2, CA7, CDC25B, CDK6, CSNK2A1, CYP19A1, CYP1A1, CYP1B1, DNMT1, DRD1, DRD2, DRD3, DRD5, DUSP3, DYRK1A, EGFR, ERBB2, ESR1, ESR2, ESRRA, ESRRB, F3, FABP3, FABP4, FLT3, GBA, GPER1, GPR35, HCAR2, HIF1A, HSPA1A, HTR1A, HTR2A, HTR2B, HTR6, IDO1, IGF1R, INSR, KDR, MET, MIF, MMP1, MMP12, MMP2, MMP9, NR3C1, PGR, PIK3CA, PIK3CB, PIM1, PPARA, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, PTGS2, PTPN1, RORC, SMAD3, SRC, TEK, TERT, TNKS, TNKS2, TOP2A, TRPV1, XDH |
10.7358 |
|
[BP] GO:0031325 |
positive regulation of cellular metabolic process
|
ADORA1, ADRA1A, ADRB1, APP, AR, AURKB, BCL2, CDC25B, DNMT1, DRD1, DRD2, DRD3, DRD5, DYRK1A, EGFR, ERBB2, ESR1, ESR2, ESRRA, ESRRB, F3, FABP3, FLT3, GBA, GPER1, HIF1A, HSPA1A, HTR2A, HTR2B, IGF1R, INSR, KDR, MET, MIF, MMP12, MMP9, NR3C1, PGR, PIK3CA, PIK3CB, PPARA, PRKCA, PRKCD, PRKCE, PRKCG, PTGS2, PTPN1, RORC, SMAD3, SRC, TEK, TERT, TNKS, TNKS2, TOP2A, TRPV1, XDH |
10.7358 |
|
[BP] GO:0070887 |
cellular response to chemical stimulus
|
AKR1B1, ALPL, APEX1, APP, AR, AXL, BCL2, CDK6, CYP1A1, CYP1A2, CYP1B1, DNMT1, DRD1, DRD5, EGFR, ERBB2, ESR1, FABP4, FLT3, GBA, GPER1, HIF1A, HSPA1A, IGF1R, INSR, KDR, MMP2, MMP9, NR3C1, PIK3CA, PRKCB, PRKCD, PRKCE, PTGS2, RORC, SMAD3, SRC, TERT, TRPV1 |
10.4529 |
|
[BP] GO:0071310 |
cellular response to organic substance
|
AKR1B1, ALPL, APEX1, APP, AR, AXL, BCL2, CDK6, CYP1A1, CYP1B1, DNMT1, DRD1, DRD5, EGFR, ERBB2, ESR1, FABP4, FLT3, GBA, GPER1, HIF1A, IGF1R, INSR, KDR, MMP2, NR3C1, PIK3CA, PRKCB, PRKCD, PRKCE, PTGS2, RORC, SMAD3, SRC, TRPV1 |
10.179 |
|
[BP] GO:0048878 |
chemical homeostasis
|
ABCG2, ADRA1A, AKR1B1, APP, BCL2, CA12, CA2, CA7, CACNA1C, DRD1, DRD2, DRD3, DRD5, EGFR, ESR1, FABP3, FABP4, GBA, GPER1, GPR35, HIF1A, HTR2A, HTR2B, INSR, MET, PIK3CA, PIK3CB, PRKCB, PRKCE, SMAD3, TRPV1 |
10.1566 |
|
[BP] GO:0008284 |
positive regulation of cell proliferation
|
AKR1B1, AR, BCL2, CDC25B, CDK6, CSNK2A1, DRD2, DRD3, EGFR, ERBB2, ESR1, F3, FLT3, GPER1, HIF1A, HTR1A, HTR2A, HTR2B, IGF1R, INSR, KDR, MIF, MMP12, MMP2, MMP9, PIM1, PRKCA, PTGS2, TEK, TERT |
10.1129 |
|
[BP] GO:0060548 |
negative regulation of cell death
|
ADORA1, AKR1B1, AR, AURKB, AXL, BCL2, CSNK2A1, EGFR, GBA, GLO1, HIF1A, HSPA1A, HTR2B, IDO1, IGF1R, KDR, MET, MIF, MMP9, PIK3CA, PIM1, PPARA, PRKCA, PRKCD, PRKCG, PTGS2, PTPN1, SMAD3, SRC, TEK, TERT |
10.0998 |
|
[BP] GO:0009893 |
positive regulation of metabolic process
|
ADORA1, ADRA1A, ADRB1, APP, AR, AURKB, BCL2, CDC25B, CSNK2A1, DNMT1, DRD1, DRD2, DRD3, DRD5, DYRK1A, EGFR, ERBB2, ESR1, ESR2, ESRRA, ESRRB, F3, FABP3, FLT3, GBA, GPER1, HIF1A, HSPA1A, HTR2A, HTR2B, IGF1R, INSR, KDR, MET, MIF, MMP12, MMP9, NR3C1, PGR, PIK3CA, PIK3CB, PPARA, PRKCA, PRKCD, PRKCE, PRKCG, PTGS2, PTPN1, RORC, SMAD3, SRC, TEK, TERT, TNKS, TNKS2, TOP2A, TRPV1, XDH |
9.9454 |
|
[BP] GO:0033993 |
response to lipid
|
ALPL, AR, AXL, BCL2, CA2, CA9, CDK6, CSNK2A1, CYP1A1, CYP1A2, EGFR, ESR1, ESRRA, FABP3, FLT3, GBA, GPER1, HSD11B2, HSD17B2, HTR5A, IDO1, NR3C1, PRKCE, PTGS2, RORC, SRC, TYR |
9.88202 |
|
[BP] GO:0019220 |
regulation of phosphate metabolic process
|
ADORA1, ADRA1A, ADRB1, APP, AR, BCL2, CDC25B, DRD1, DRD2, DRD3, DRD5, DUSP3, EGFR, ERBB2, ESRRB, FABP3, FABP4, FLT3, GBA, GPER1, HIF1A, HTR2A, HTR2B, IGF1R, INSR, KDR, MIF, MMP9, NUAK1, PIK3CA, PIK3CB, PPARA, PRKCA, PRKCD, PRKCE, PTGS2, PTPN1, SMAD3, SRC, TEK, XDH |
9.74866 |
|
[BP] GO:0032879 |
regulation of localization
|
ABCB1, ACHE, ADORA1, ADORA3, APEX1, APP, AR, AXL, BCL2, CA2, CA7, CACNA1C, CDK6, CSNK2A1, CYP19A1, CYP1B1, DRD1, DRD2, DRD3, EGFR, ERBB2, F3, GPER1, GPR35, HCAR2, HIF1A, HSPA1A, HTR1A, HTR2A, HTR2B, IGF1R, INSR, KDR, MET, MIF, MMP12, MMP9, PIK3CB, PPARA, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, PTGS2, PTPN1, SMAD3, SRC, TEK, TERT, TRPV1 |
9.73297 |
|
[BP] GO:0051174 |
regulation of phosphorus metabolic process
|
ADORA1, ADRA1A, ADRB1, APP, AR, BCL2, CDC25B, DRD1, DRD2, DRD3, DRD5, DUSP3, EGFR, ERBB2, ESRRB, FABP3, FABP4, FLT3, GBA, GPER1, HIF1A, HTR2A, HTR2B, IGF1R, INSR, KDR, MIF, MMP9, NUAK1, PIK3CA, PIK3CB, PPARA, PRKCA, PRKCD, PRKCE, PTGS2, PTPN1, SMAD3, SRC, TEK, XDH |
9.64933 |
|
[BP] GO:0043069 |
negative regulation of programmed cell death
|
ADORA1, AKR1B1, AR, AURKB, AXL, BCL2, CSNK2A1, EGFR, GLO1, HIF1A, HSPA1A, HTR2B, IDO1, IGF1R, KDR, MET, MIF, MMP9, PIK3CA, PIM1, PRKCA, PRKCD, PRKCG, PTGS2, PTPN1, SMAD3, SRC, TEK, TERT |
9.59217 |
|
[BP] GO:2000145 |
regulation of cell motility
|
ADORA1, ADORA3, APEX1, APP, BCL2, CDK6, CYP19A1, CYP1B1, DRD1, DRD2, EGFR, ERBB2, F3, GPER1, HIF1A, IGF1R, INSR, KDR, MET, MIF, MMP9, PRKCA, PRKCE, PTGS2, SMAD3, SRC, TEK, TERT |
9.37182 |
|
[BP] GO:0040012 |
regulation of locomotion
|
ADORA1, ADORA3, APEX1, APP, BCL2, CDK6, CYP19A1, CYP1B1, DRD1, DRD2, DRD3, EGFR, ERBB2, F3, GPER1, HIF1A, IGF1R, INSR, KDR, MET, MIF, MMP9, PRKCA, PRKCE, PTGS2, SMAD3, SRC, TEK, TERT |
9.33755 |
|
[BP] GO:0019748 |
secondary metabolic process
|
AKR1B1, AKR1B10, BCL2, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, CYP2D6, TYR |
9.31493 |
|
[BP] GO:0051270 |
regulation of cellular component movement
|
ADORA1, ADORA3, APEX1, APP, BCL2, CACNA1C, CDK6, CYP19A1, CYP1B1, DRD1, DRD2, EGFR, ERBB2, F3, GPER1, HIF1A, IGF1R, INSR, KDR, MET, MIF, MMP9, PRKCA, PRKCE, PTGS2, SMAD3, SRC, TEK, TERT |
9.31493 |
|
[BP] GO:0032501 |
multicellular organismal process
|
ADORA1, ADRA1A, ADRB1, AKR1B1, AKR1B10, ALOX5, ALPI, ALPL, APP, AR, AXL, BCL2, CACNA1C, CYP19A1, CYP1A2, CYP1B1, DRD1, DRD2, DRD3, DRD5, DUSP3, EGFR, ESR1, ESRRB, F3, FABP4, GAA, GBA, GPER1, HIF1A, HSD11B2, HSD17B2, HTR1A, HTR2A, HTR2B, HTR7, IDO1, IGF1R, INSR, MET, MGAM, MMP1, MMP12, MMP2, MMP9, PIK3CA, PIM1, PPARA, PRKCD, PRKCG, PTGS2, RORC, SMAD3, SRC, TEK, TNKS2, TRPV1, TYR |
9.10668 |
|
[BP] GO:0003018 |
None
|
ADORA1, ADRA1A, ADRB1, DRD1, DRD5, EGFR, GPER1, HTR1A, HTR2A, HTR2B, HTR7, PTGS2, SRC, TEK |
9.05261 |
|
[BP] GO:0043066 |
negative regulation of apoptotic process
|
ADORA1, AKR1B1, AR, AURKB, AXL, BCL2, CSNK2A1, EGFR, GLO1, HIF1A, HSPA1A, HTR2B, IDO1, IGF1R, KDR, MIF, MMP9, PIK3CA, PIM1, PRKCA, PRKCD, PRKCG, PTGS2, PTPN1, SMAD3, SRC, TEK, TERT |
9.02545 |
|
[BP] GO:0010604 |
positive regulation of macromolecule metabolic process
|
ADORA1, ADRA1A, APP, AR, AURKB, BCL2, CDC25B, CSNK2A1, DNMT1, DRD1, DRD2, DRD3, DYRK1A, EGFR, ERBB2, ESR1, ESR2, ESRRA, ESRRB, F3, FLT3, GBA, GPER1, HIF1A, HSPA1A, HTR2A, HTR2B, IGF1R, INSR, KDR, MET, MIF, MMP12, MMP9, NR3C1, PGR, PIK3CA, PIK3CB, PPARA, PRKCA, PRKCD, PRKCE, PRKCG, PTGS2, PTPN1, RORC, SMAD3, SRC, TEK, TERT, TNKS, TNKS2, TOP2A, XDH |
9.02545 |
|
[BP] GO:0050801 |
ion homeostasis
|
ABCG2, ADRA1A, APP, BCL2, CA12, CA2, CA7, CACNA1C, DRD1, DRD2, DRD3, DRD5, EGFR, ESR1, FABP3, GPER1, GPR35, HIF1A, HTR2A, HTR2B, PIK3CB, PRKCB, PRKCE, SMAD3, TRPV1 |
9.02545 |
|
[BP] GO:0010648 |
negative regulation of cell communication
|
ACHE, ADORA1, ADRA1A, AR, BCL2, DRD1, DRD2, DRD3, DRD5, DUSP3, DYRK1A, EGFR, ERBB2, ESR1, ESR2, GBA, GPER1, GPR35, HIF1A, HSPA1A, HTR2A, IGF1R, MET, MIF, MMP12, MMP9, PRKCB, PRKCD, PTGS2, PTPN1, SMAD3, SRC, TERT, XDH |
8.96386 |
|
[BP] GO:0023057 |
negative regulation of signaling
|
ACHE, ADORA1, ADRA1A, AR, BCL2, DRD1, DRD2, DRD3, DRD5, DUSP3, DYRK1A, EGFR, ERBB2, ESR1, ESR2, GBA, GPER1, GPR35, HIF1A, HSPA1A, HTR2A, IGF1R, MET, MIF, MMP12, MMP9, PRKCB, PRKCD, PTGS2, PTPN1, SMAD3, SRC, TERT, XDH |
8.93246 |
|
[BP] GO:0010817 |
regulation of hormone levels
|
ACHE, ADORA1, AKR1B1, CACNA1C, CYP19A1, CYP1A1, CYP1B1, DRD2, EGFR, ESR1, GPER1, HCAR2, HIF1A, HSD11B1, HSD11B2, HSD17B1, HSD17B2, HTR1A, HTR2A, PRKCA, PRKCE, SLC22A1 |
8.90759 |
|
[BP] GO:0009628 |
response to abiotic stimulus
|
ADORA1, ADRB1, AKR1B1, APP, AURKB, BCL2, CA2, CYP1A1, DRD1, DRD2, DRD3, EGFR, GBA, HIF1A, HSD11B2, HSPA1A, HTR2A, HTR2B, MMP2, POLB, PPARA, PRKCB, PRKCE, PTGS2, SMAD3, SRC, TEK, TERT, TRPV1, TYR |
8.88803 |
|
[BP] GO:1901701 |
cellular response to oxygen-containing compound
|
AKR1B1, APEX1, APP, AR, AXL, CDK6, CYP1B1, DNMT1, DRD1, DRD5, EGFR, ESR1, GPER1, IGF1R, INSR, MMP2, MMP9, NR3C1, PIK3CA, PRKCB, PRKCD, PRKCE, PTGS2, RORC, SRC, TRPV1 |
8.74458 |
|
[BP] GO:0015711 |
organic anion transport
|
ABCB1, CA1, CA12, CA14, CA2, CA3, CA4, CA5A, CA5B, CA6, CA7, CA9, DRD2, DRD3, FABP3, PPARA, SLC22A1, SLC22A2, SLC22A3, TRPV1 |
8.71159 |
|
[BP] GO:0098771 |
inorganic ion homeostasis
|
ABCG2, ADRA1A, APP, BCL2, CA12, CA2, CA7, CACNA1C, DRD1, DRD2, DRD3, DRD5, EGFR, ESR1, GPER1, GPR35, HIF1A, HTR2A, HTR2B, PIK3CB, PRKCB, PRKCE, SMAD3, TRPV1 |
8.61943 |
|
[BP] GO:0030334 |
regulation of cell migration
|
ADORA1, ADORA3, APEX1, APP, BCL2, CYP19A1, CYP1B1, DRD1, DRD2, EGFR, F3, GPER1, HIF1A, IGF1R, INSR, KDR, MET, MIF, MMP9, PRKCA, PRKCE, PTGS2, SMAD3, SRC, TEK, TERT |
8.52037 |
|
[BP] GO:2000021 |
regulation of ion homeostasis
|
ADORA1, BCL2, CA2, CA7, CACNA1C, DRD1, DRD2, DRD3, GPER1, HTR2A, HTR2B, KDR, PRKCE, SRC, TRPV1 |
8.50972 |
|
[BP] GO:0048523 |
negative regulation of cellular process
|
ACHE, ADORA1, ADORA3, ADRA1A, AKR1B1, APEX1, APP, AR, AURKB, AXL, BCL2, CDK6, CSNK2A1, CYP19A1, CYP1B1, CYP2D6, DNMT1, DRD1, DRD2, DRD3, DRD5, DUSP3, DYRK1A, EGFR, ERBB2, ESR1, ESR2, ESRRA, ESRRB, FABP3, FABP4, GBA, GLO1, GPER1, GPR35, HIF1A, HSPA1A, HTR2A, HTR2B, IDO1, IGF1R, KDR, MET, MIF, MMP12, MMP9, NR3C1, PIK3CA, PIM1, PPARA, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, PTGS2, PTPN1, RORC, SMAD3, SRC, TEK, TERT, TNKS, TNKS2, TOP2A, TRPV1, XDH |
8.48458 |
|
[BP] GO:0043408 |
regulation of MAPK cascade
|
ADORA1, ADRA1A, APP, AR, DRD2, DUSP3, EGFR, ERBB2, FLT3, GBA, GPER1, HTR2A, HTR2B, IGF1R, INSR, KDR, MIF, PIK3CB, PRKCA, PRKCD, PRKCE, PTPN1, SRC, TEK, XDH |
8.43444 |
|
[BP] GO:0050790 |
regulation of catalytic activity
|
ADORA1, ADORA3, ADRA1A, ADRB1, APP, AR, AURKB, BCL2, CDC25B, CSNK2A1, DRD1, DRD2, DRD3, DRD5, DUSP3, EGFR, ERBB2, ESR1, F3, FABP4, FLT3, GBA, GPER1, HIF1A, HSPA1A, HTR2A, HTR2B, IGF1R, INSR, MIF, MMP9, NUAK1, PIK3CA, PIK3CB, PRKCA, PRKCD, PRKCE, PTGS2, PTPN1, SMAD3, SRC, TEK, TERT, TNKS, XDH |
8.40324 |
|
[BP] GO:0019725 |
cellular homeostasis
|
ABCG2, ADRA1A, APEX1, APP, BCL2, CA2, CA7, CACNA1C, DRD1, DRD2, DRD3, DRD5, ESR1, GAA, GPER1, GPR35, HIF1A, HTR2A, HTR2B, PIK3CA, PIK3CB, POLA1, PRKCB, PRKCE, SMAD3, TRPV1 |
8.37364 |
|
[BP] GO:0042327 |
positive regulation of phosphorylation
|
ADORA1, ADRA1A, APP, AR, BCL2, CDC25B, DRD2, EGFR, ERBB2, ESRRB, FLT3, GPER1, HIF1A, HTR2A, HTR2B, INSR, KDR, MIF, MMP9, PIK3CA, PIK3CB, PRKCA, PRKCD, PRKCE, PTGS2, PTPN1, SRC, TEK, XDH |
8.35605 |
|
[BP] GO:0051049 |
regulation of transport
|
ABCB1, ACHE, ADORA1, APP, AXL, BCL2, CA2, CA7, CACNA1C, CYP19A1, DRD1, DRD2, DRD3, EGFR, ERBB2, GPER1, GPR35, HCAR2, HIF1A, HSPA1A, HTR1A, HTR2A, HTR2B, INSR, MIF, MMP12, MMP9, PIK3CB, PPARA, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, PTGS2, PTPN1, SMAD3, SRC, TERT, TRPV1 |
8.35157 |
|
[BP] GO:0048583 |
regulation of response to stimulus
|
ABCB1, ADORA1, ADRA1A, ADRB1, AKR1B1, APP, AR, AURKB, AXL, BCL2, CDK6, CSNK2A1, CYP19A1, CYP1B1, DRD1, DRD2, DRD3, DUSP3, DYRK1A, EGFR, ERBB2, ESR1, ESR2, ESRRA, F3, FABP4, FLT3, GBA, GPER1, GPR35, HIF1A, HSPA1A, HTR2A, HTR2B, HTR6, IDO1, IGF1R, INSR, KDR, MET, MIF, MMP12, MMP2, MMP9, NUAK1, PIK3CA, PIK3CB, PPARA, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, PTGS2, PTPN1, SMAD3, SRC, TEK, TERT, TNKS, TNKS2, XDH |
8.34632 |
|
[BP] GO:0006796 |
phosphate-containing compound metabolic process
|
ACHE, ALPI, ALPL, APEX1, APP, AURKB, AXL, BCL2, CA3, CDC25B, CDK6, CSNK2A1, DRD1, DRD2, DUSP3, DYRK1A, EGFR, ERBB2, FLT3, HSPA1A, HTR2B, IGF1R, INSR, KDR, MET, NUAK1, PIK3CA, PIK3CB, PIM1, POLB, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, PTGS2, PTPN1, SRC, TEK, TNKS, XDH |
8.25939 |
|
[BP] GO:0051240 |
positive regulation of multicellular organismal process
|
ADRA1A, ADRB1, APP, AR, AXL, BCL2, CA2, CYP1B1, DRD2, DRD3, EGFR, ESRRB, F3, GBA, GPER1, HCAR2, HIF1A, HSPA1A, HTR2A, HTR2B, IDO1, KDR, MET, MIF, MMP12, MMP9, PIM1, PRKCA, PRKCB, PRKCE, PTGS2, SMAD3, SRC, TEK, TERT, TRPV1 |
8.25939 |
|
[BP] GO:0006468 |
protein phosphorylation
|
APP, AURKB, AXL, BCL2, CDC25B, CDK6, CSNK2A1, DRD1, DYRK1A, EGFR, ERBB2, FLT3, HTR2B, IGF1R, INSR, KDR, MET, NUAK1, PIK3CA, PIM1, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, SRC, TEK, TNKS |
8.20797 |
|
[BP] GO:0080134 |
regulation of response to stress
|
ABCB1, ADORA1, APP, CDK6, CYP19A1, DRD2, DUSP3, DYRK1A, EGFR, ESR1, F3, FABP4, GBA, GPER1, HIF1A, HSPA1A, IDO1, IGF1R, MET, MIF, MMP12, MMP2, NUAK1, PPARA, PRKCA, PRKCD, PRKCE, PRKCG, PTGS2, PTPN1, SMAD3, SRC, TEK, TERT, XDH |
8.19403 |
|
[BP] GO:0051716 |
cellular response to stimulus
|
AKR1B1, ALPL, APEX1, APP, AR, AURKB, AXL, BCL2, CA2, CA9, CDK6, CYP1A1, CYP1A2, CYP1B1, DNMT1, DRD1, DRD5, EGFR, ERBB2, ESR1, FABP4, FLT3, GBA, GPER1, HIF1A, HSPA1A, IGF1R, INSR, KDR, MIF, MMP2, MMP9, NR3C1, NUAK1, PIK3CA, POLA1, POLB, PRKCB, PRKCD, PRKCE, PTGS2, PTPN1, RORC, SMAD3, SRC, TERT, TOP2A, TRPV1 |
8.16624 |
|
[BP] GO:0032502 |
developmental process
|
ACHE, ADORA1, ADRA1A, ADRB1, AKR1B1, ALPL, APEX1, APP, AR, AURKB, AXL, BCL2, CA2, CA9, CACNA1C, CDC25B, CDK6, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, DRD1, DRD2, DUSP3, DYRK1A, EGFR, ERBB2, ESR1, ESRRA, ESRRB, FABP4, FLT3, FUT7, GAA, GBA, GBA2, GLO1, HIF1A, HSD11B1, HSD17B2, HTR2A, HTR2B, HTR5A, INSR, KDR, MET, MIF, MMP2, MMP9, PGR, PIK3CA, PIK3CB, PIM1, POLB, PPARA, PRKCA, PRKCD, PTGS2, RORC, SIGMAR1, SMAD3, SRC, TEK, TERT, TNKS2, TOP2A, TYR |
8.16222 |
|
[BP] GO:0030003 |
cellular cation homeostasis
|
ABCG2, ADRA1A, APP, BCL2, CA2, CA7, CACNA1C, DRD1, DRD2, DRD3, DRD5, ESR1, GPER1, GPR35, HIF1A, HTR2A, HTR2B, PIK3CB, PRKCB, PRKCE, SMAD3, TRPV1 |
8.11704 |
|
[BP] GO:0043410 |
positive regulation of MAPK cascade
|
ADORA1, ADRA1A, APP, AR, DRD2, EGFR, ERBB2, FLT3, GPER1, HTR2A, HTR2B, INSR, KDR, MIF, PIK3CB, PRKCA, PRKCE, PTPN1, SRC, TEK, XDH |
8.11449 |
|
[BP] GO:0048519 |
negative regulation of biological process
|
ACHE, ADORA1, ADORA3, ADRA1A, ADRB1, AKR1B1, APEX1, APP, AR, AURKB, AXL, BCL2, CDK6, CSNK2A1, CYP19A1, CYP1B1, CYP2D6, DNMT1, DRD1, DRD2, DRD3, DRD5, DUSP3, DYRK1A, EGFR, ERBB2, ESR1, ESR2, ESRRA, ESRRB, FABP3, FABP4, GBA, GLO1, GPER1, GPR35, HCAR2, HIF1A, HSPA1A, HTR2A, HTR2B, IDO1, IGF1R, KDR, MET, MIF, MMP12, MMP9, NR3C1, PGR, PIK3CA, PIM1, PPARA, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, PTGS2, PTPN1, RORC, SMAD3, SRC, TEK, TERT, TNKS, TNKS2, TOP2A, TRPV1, XDH |
8.11381 |
|
[BP] GO:0055080 |
cation homeostasis
|
ABCG2, ADRA1A, APP, BCL2, CA2, CA7, CACNA1C, DRD1, DRD2, DRD3, DRD5, EGFR, ESR1, GPER1, GPR35, HIF1A, HTR2A, HTR2B, PIK3CB, PRKCB, PRKCE, SMAD3, TRPV1 |
8.09258 |
|
[BP] GO:0007165 |
signal transduction
|
ADORA1, ADORA3, ADRA1A, ADRB1, AKR1B1, APP, AR, AXL, BCL2, CA1, CA2, CACNA1C, CDK6, CSNK2A1, CYP1B1, DNMT1, DRD1, DRD2, DRD3, DRD5, EGFR, ERBB2, ESR1, ESR2, ESRRA, ESRRB, F3, FLT3, GPER1, GPR35, HCAR2, HIF1A, HTR1A, HTR2A, HTR2B, HTR5A, HTR6, HTR7, IGF1R, INSR, KDR, MET, MIF, MMP2, MMP9, NR3C1, NR3C2, NUAK1, PGR, PIK3CA, PIK3CB, PIM1, POLB, PPARA, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, PTPN1, RORC, SIGMAR1, SMAD3, SRC, TEK, TNKS, TNKS2, TRPV1 |
8.09135 |
|
[BP] GO:0051239 |
regulation of multicellular organismal process
|
ADORA1, ADORA3, ADRA1A, ADRB1, APP, AR, AXL, BCL2, CA2, CACNA1C, CDK6, CYP1B1, DRD2, DRD3, EGFR, ERBB2, ESR1, ESRRA, ESRRB, F3, GAA, GBA, GPER1, GPR35, HCAR2, HIF1A, HSPA1A, HTR2A, HTR2B, IDO1, INSR, KDR, MET, MIF, MMP12, MMP9, PIK3CA, PIM1, PRKCA, PRKCB, PRKCD, PRKCE, PTGS2, SMAD3, SRC, TEK, TERT, TNKS2, TRPV1, XDH |
8.02723 |
|
[BP] GO:0065009 |
regulation of molecular function
|
ABCB1, ADORA1, ADORA3, ADRA1A, ADRB1, APP, AR, AURKB, BCL2, CDC25B, CSNK2A1, CYP1B1, CYP2D6, DRD1, DRD2, DRD3, DRD5, DUSP3, EGFR, ERBB2, ESR1, ESR2, F3, FABP4, FLT3, GBA, GPER1, GPR35, HIF1A, HSPA1A, HTR2A, HTR2B, IGF1R, INSR, MET, MIF, MMP9, NUAK1, PIK3CA, PIK3CB, PIM1, PPARA, PRKCA, PRKCB, PRKCD, PRKCE, PTGS2, PTPN1, SMAD3, SRC, TEK, TERT, TNKS, TRPV1, XDH |
8.01931 |
|
[BP] GO:0097746 |
None
|
ADORA1, ADRA1A, ADRB1, DRD1, DRD5, EGFR, GPER1, HTR1A, HTR2A, HTR2B, HTR7, PTGS2 |
8.01894 |
|
[BP] GO:0035296 |
None
|
ADORA1, ADRA1A, ADRB1, DRD1, DRD5, EGFR, GPER1, HTR1A, HTR2A, HTR2B, HTR7, PTGS2 |
8.01894 |
|
[BP] GO:0044093 |
positive regulation of molecular function
|
ABCB1, ADORA1, ADRA1A, ADRB1, APP, AR, AURKB, BCL2, CDC25B, DRD2, DRD5, EGFR, ERBB2, ESR1, ESR2, F3, FLT3, GPER1, HIF1A, HSPA1A, HTR2A, HTR2B, INSR, MET, MIF, MMP9, PIK3CA, PIK3CB, PRKCB, PRKCD, PRKCE, PTPN1, SMAD3, SRC, TEK, TERT, TNKS, XDH |
8.01233 |
|
[BP] GO:0010243 |
response to organonitrogen compound
|
AKR1B1, APEX1, APP, DNMT1, DRD1, DRD2, DRD3, DRD5, EGFR, FABP3, FLT3, GPER1, HSD11B2, IGF1R, INSR, MMP2, PPARA, PRKCD, PRKCE, PRKCG, PTGS2, SRC, TEK, TRPV1, TYR |
8.01233 |
|
[BP] GO:0044255 |
cellular lipid metabolic process
|
ACHE, AKR1B10, ALOX5, ALPI, CSNK2A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, CYP2D6, DRD2, EGFR, ERBB2, FABP3, FABP4, FUCA1, FUT7, GBA, GBA2, MET, MIF, PIK3CA, PIK3CB, PPARA, PTGS1, PTGS2, TBXAS1 |
7.98778 |
|
[BP] GO:0006873 |
cellular ion homeostasis
|
ABCG2, ADRA1A, APP, BCL2, CA2, CA7, CACNA1C, DRD1, DRD2, DRD3, DRD5, ESR1, GPER1, GPR35, HIF1A, HTR2A, HTR2B, PIK3CB, PRKCB, PRKCE, SMAD3, TRPV1 |
7.9722 |
|
[BP] GO:0033559 |
unsaturated fatty acid metabolic process
|
ALOX5, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, CYP2D6, MIF, PTGS1, PTGS2, TBXAS1 |
7.9722 |
|
[BP] GO:0009966 |
regulation of signal transduction
|
ADORA1, ADRA1A, ADRB1, AKR1B1, APP, AR, AURKB, AXL, BCL2, CSNK2A1, CYP1B1, DRD2, DRD3, DUSP3, DYRK1A, EGFR, ERBB2, ESR1, ESR2, F3, FLT3, GBA, GPER1, GPR35, HIF1A, HSPA1A, HTR2A, HTR2B, HTR6, IGF1R, INSR, KDR, MET, MIF, MMP12, MMP9, NUAK1, PIK3CA, PIK3CB, PRKCA, PRKCB, PRKCD, PRKCE, PTGS2, PTPN1, SMAD3, SRC, TEK, TERT, TNKS, TNKS2, XDH |
7.95705 |
|
[BP] GO:0072507 |
divalent inorganic cation homeostasis
|
ADRA1A, APP, BCL2, CACNA1C, DRD1, DRD2, DRD3, DRD5, EGFR, ESR1, GPER1, GPR35, HTR2A, HTR2B, PIK3CB, PRKCB, PRKCE, SMAD3, TRPV1 |
7.94661 |
|
[BP] GO:0042325 |
regulation of phosphorylation
|
ADORA1, ADRA1A, APP, AR, BCL2, CDC25B, DRD1, DRD2, DUSP3, EGFR, ERBB2, ESRRB, FABP4, FLT3, GBA, GPER1, HIF1A, HTR2A, HTR2B, IGF1R, INSR, KDR, MIF, MMP9, PIK3CA, PIK3CB, PPARA, PRKCA, PRKCD, PRKCE, PTGS2, PTPN1, SRC, TEK, XDH |
7.94579 |
|
[BP] GO:0055082 |
cellular chemical homeostasis
|
ABCG2, ADRA1A, APP, BCL2, CA2, CA7, CACNA1C, DRD1, DRD2, DRD3, DRD5, ESR1, GPER1, GPR35, HIF1A, HTR2A, HTR2B, PIK3CA, PIK3CB, PRKCB, PRKCE, SMAD3, TRPV1 |
7.82557 |
|
[BP] GO:0043401 |
steroid hormone mediated signaling pathway
|
AR, ESR1, ESR2, ESRRA, ESRRB, GPER1, NR3C1, NR3C2, PGR, PPARA, RORC, SRC |
7.82557 |
|
[BP] GO:0035556 |
intracellular signal transduction
|
ADRA1A, ADRB1, AKR1B1, AXL, BCL2, CACNA1C, CYP1B1, DNMT1, DRD1, DRD2, DRD3, DRD5, EGFR, ERBB2, GPER1, HTR2A, HTR2B, HTR5A, IGF1R, INSR, KDR, MET, MIF, NUAK1, PIK3CA, PIK3CB, POLB, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, PTPN1, SRC, TEK |
7.78697 |
|
[BP] GO:0019369 |
arachidonic acid metabolic process
|
CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, CYP2D6, PTGS1, PTGS2, TBXAS1 |
7.78017 |
|
[BP] GO:0006793 |
phosphorus metabolic process
|
ACHE, ALPI, ALPL, APEX1, APP, AURKB, AXL, BCL2, CA3, CDC25B, CDK6, CSNK2A1, DRD1, DRD2, DUSP3, DYRK1A, EGFR, ERBB2, FLT3, HSPA1A, HTR2B, IGF1R, INSR, KDR, MET, NUAK1, PIK3CA, PIK3CB, PIM1, POLB, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, PTGS2, PTPN1, SRC, TEK, TNKS, XDH |
7.77415 |
|
[BP] GO:0050880 |
None
|
ADORA1, ADRA1A, ADRB1, DRD1, DRD5, EGFR, GPER1, HTR1A, HTR2A, HTR2B, HTR7, PTGS2 |
7.765 |
|
[BP] GO:0006875 |
cellular metal ion homeostasis
|
ABCG2, ADRA1A, APP, BCL2, CACNA1C, DRD1, DRD2, DRD3, DRD5, ESR1, GPER1, GPR35, HIF1A, HTR2A, HTR2B, PIK3CB, PRKCB, PRKCE, SMAD3, TRPV1 |
7.76069 |
|
[BP] GO:0006874 |
cellular calcium ion homeostasis
|
ADRA1A, APP, BCL2, CACNA1C, DRD1, DRD2, DRD3, DRD5, ESR1, GPER1, GPR35, HTR2A, HTR2B, PIK3CB, PRKCB, PRKCE, SMAD3, TRPV1 |
7.7419 |
|
[BP] GO:0035150 |
None
|
ADORA1, ADRA1A, ADRB1, DRD1, DRD5, EGFR, GPER1, HTR1A, HTR2A, HTR2B, HTR7, PTGS2 |
7.73664 |
|
[BP] GO:0055065 |
metal ion homeostasis
|
ABCG2, ADRA1A, APP, BCL2, CACNA1C, DRD1, DRD2, DRD3, DRD5, EGFR, ESR1, GPER1, GPR35, HIF1A, HTR2A, HTR2B, PIK3CB, PRKCB, PRKCE, SMAD3, TRPV1 |
7.71597 |
|
[BP] GO:0006690 |
icosanoid metabolic process
|
ALOX5, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, CYP2D6, MIF, PTGS1, PTGS2, TBXAS1 |
7.70307 |
|
[BP] GO:0003013 |
None
|
ADORA1, ADRA1A, ADRB1, DRD1, DRD5, EGFR, GPER1, HTR1A, HTR2A, HTR2B, HTR7, PTGS2, SRC, TEK |
7.69885 |
|
[BP] GO:0008202 |
steroid metabolic process
|
AKR1B1, AKR1B10, APP, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A6, CYP2D6, ESR1, GBA2, HSD11B1, HSD11B2, HSD17B1, HSD17B2 |
7.66029 |
|
[BP] GO:0070482 |
response to oxygen levels
|
ADORA1, BCL2, CYP1A1, DRD2, HIF1A, HSD11B2, MMP2, POLB, PPARA, PRKCB, PRKCE, PTGS2, SMAD3, SRC, TEK, TERT |
7.65425 |
|
[BP] GO:0009891 |
positive regulation of biosynthetic process
|
ADRB1, APP, AR, AURKB, DRD1, DRD2, DRD3, DRD5, EGFR, ERBB2, ESR1, ESR2, ESRRA, ESRRB, FABP3, GBA, GPER1, HIF1A, HTR2A, HTR2B, IGF1R, INSR, KDR, MET, MMP12, NR3C1, PGR, PPARA, PRKCD, PTGS2, RORC, SMAD3, SRC, TERT, TNKS, TNKS2, TOP2A, TRPV1 |
7.64433 |
|
[BP] GO:0030335 |
positive regulation of cell migration
|
APP, BCL2, DRD1, EGFR, F3, GPER1, HIF1A, IGF1R, INSR, KDR, MET, MMP9, PRKCA, PRKCE, PTGS2, SMAD3, SRC, TEK, TERT |
7.60728 |
|
[BP] GO:0071704 |
organic substance metabolic process
|
ABCG2, ACHE, ADORA1, AKR1B1, AKR1B10, ALDH2, ALOX5, ALPI, ALPL, AOX1, APEX1, APP, AR, AURKB, AXL, BACE1, BCL2, CDC25B, CDK6, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, CYP2D6, DAO, DNMT1, DRD1, DRD2, DRD3, DUSP3, DYRK1A, EGFR, ERBB2, ESR1, ESR2, ESRRA, ESRRB, F3, FABP3, FABP4, FLT3, FUCA1, FUT7, GAA, GBA, GBA2, GLO1, HIF1A, HSD11B1, HSD11B2, HSD17B1, HSD17B2, HSPA1A, HTR1A, HTR2B, IDO1, IGF1R, INSR, KDR, MET, MGAM, MIF, MMP1, MMP12, MMP2, MMP9, NR3C1, NR3C2, NUAK1, PGR, PIK3CA, PIK3CB, PIM1, POLA1, POLB, PPARA, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, PTGS1, PTGS2, PTPN1, RORC, SMAD3, SRC, TBXAS1, TEK, TERT, TNKS, TNKS2, TOP2A, TRPV1, TYR, XDH |
7.59087 |
|
[BP] GO:0055074 |
calcium ion homeostasis
|
ADRA1A, APP, BCL2, CACNA1C, DRD1, DRD2, DRD3, DRD5, ESR1, GPER1, GPR35, HTR2A, HTR2B, PIK3CB, PRKCB, PRKCE, SMAD3, TRPV1 |
7.56224 |
|
[BP] GO:0051896 |
regulation of protein kinase B signaling
|
AXL, DRD2, DRD3, EGFR, ERBB2, F3, GPER1, INSR, MET, PIK3CA, PIK3CB, SRC, TEK, XDH |
7.56121 |
|
[BP] GO:0001934 |
positive regulation of protein phosphorylation
|
ADORA1, ADRA1A, APP, AR, BCL2, CDC25B, DRD2, EGFR, ERBB2, FLT3, GPER1, HTR2A, HTR2B, INSR, KDR, MIF, MMP9, PIK3CA, PIK3CB, PRKCA, PRKCD, PRKCE, PTGS2, PTPN1, SRC, TEK, XDH |
7.5531 |
|
[BP] GO:0097756 |
None
|
ADORA1, ADRA1A, DRD5, HTR1A, HTR2A, HTR2B, HTR7, PTGS2 |
7.54795 |
|
[BP] GO:0048585 |
negative regulation of response to stimulus
|
ADORA1, ADRA1A, AR, BCL2, CDK6, CYP19A1, DRD1, DRD2, DRD3, DUSP3, DYRK1A, EGFR, ERBB2, ESR1, ESR2, GBA, GPER1, HIF1A, HSPA1A, IGF1R, MET, MIF, MMP12, MMP9, PPARA, PRKCB, PRKCD, PTGS2, PTPN1, SMAD3, SRC, TEK, TERT, XDH |
7.53609 |
|
[BP] GO:0072503 |
cellular divalent inorganic cation homeostasis
|
ADRA1A, APP, BCL2, CACNA1C, DRD1, DRD2, DRD3, DRD5, ESR1, GPER1, GPR35, HTR2A, HTR2B, PIK3CB, PRKCB, PRKCE, SMAD3, TRPV1 |
7.48869 |
|
[BP] GO:0050804 |
modulation of chemical synaptic transmission
|
ACHE, ADORA1, ADRA1A, APP, BACE1, CA2, CA7, DRD1, DRD2, DRD3, DRD5, EGFR, GPER1, HTR2A, PRKCE, PTGS2 |
7.47813 |
|
[BP] GO:0099177 |
regulation of trans-synaptic signaling
|
ACHE, ADORA1, ADRA1A, APP, BACE1, CA2, CA7, DRD1, DRD2, DRD3, DRD5, EGFR, GPER1, HTR2A, PRKCE, PTGS2 |
7.47813 |
|
[BP] GO:1901698 |
response to nitrogen compound
|
AKR1B1, APEX1, APP, DNMT1, DRD1, DRD2, DRD3, DRD5, EGFR, FABP3, FLT3, GPER1, HSD11B2, IGF1R, INSR, MMP2, PPARA, PRKCD, PRKCE, PRKCG, PTGS2, SRC, TEK, TRPV1, TYR |
7.43771 |
|
[BP] GO:0071407 |
cellular response to organic cyclic compound
|
ALPL, APEX1, APP, AR, CYP1A1, CYP1B1, DRD1, DRD5, EGFR, ESR1, FLT3, GPER1, NR3C1, PTGS2, RORC, SRC, TRPV1 |
7.43771 |
|
[BP] GO:0001666 |
response to hypoxia
|
ADORA1, BCL2, CYP1A1, DRD2, HIF1A, HSD11B2, MMP2, PPARA, PRKCB, PRKCE, PTGS2, SMAD3, SRC, TEK, TERT |
7.42421 |
|
[BP] GO:0044238 |
primary metabolic process
|
ACHE, ADORA1, AKR1B1, AKR1B10, ALDH2, ALOX5, ALPI, ALPL, AOX1, APEX1, APP, AR, AURKB, AXL, BACE1, BCL2, CDC25B, CDK6, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, CYP2D6, DAO, DNMT1, DRD1, DRD2, DUSP3, DYRK1A, EGFR, ERBB2, ESR1, ESR2, ESRRA, ESRRB, F3, FABP3, FABP4, FLT3, FUCA1, FUT7, GAA, GBA, GBA2, GLO1, HIF1A, HSD11B1, HSD11B2, HSD17B1, HSD17B2, HSPA1A, HTR2B, IDO1, IGF1R, INSR, KDR, MET, MGAM, MIF, MMP1, MMP12, MMP2, MMP9, NR3C1, NR3C2, NUAK1, PGR, PIK3CA, PIK3CB, PIM1, POLA1, POLB, PPARA, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, PTGS1, PTGS2, PTPN1, RORC, SMAD3, SRC, TBXAS1, TEK, TERT, TNKS, TNKS2, TOP2A, TRPV1, TYR, XDH |
7.41459 |
|
[BP] GO:0051050 |
positive regulation of transport
|
ABCB1, ACHE, ADORA1, APP, AXL, BCL2, CA2, CYP19A1, DRD1, DRD2, DRD3, EGFR, ERBB2, GPER1, HCAR2, HIF1A, HTR2B, INSR, MIF, MMP12, PRKCD, PRKCE, PTGS2, SMAD3, SRC, TERT, TRPV1 |
7.41162 |
|
[BP] GO:2000147 |
positive regulation of cell motility
|
APP, BCL2, DRD1, EGFR, F3, GPER1, HIF1A, IGF1R, INSR, KDR, MET, MMP9, PRKCA, PRKCE, PTGS2, SMAD3, SRC, TEK, TERT |
7.39796 |
|
[BP] GO:0055114 |
oxidation-reduction process
|
AKR1B1, AKR1B10, ALDH2, ALOX5, AOX1, APEX1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, CYP2D6, DAO, GAA, HSD11B1, HSD11B2, HSD17B1, HSD17B2, IDO1, NQO2, PTGS1, PTGS2, TBXAS1, TYR, XDH |
7.38857 |
|
[BP] GO:0031399 |
regulation of protein modification process
|
ADORA1, ADRA1A, APP, AR, BCL2, CDC25B, DNMT1, DRD1, DRD2, DUSP3, DYRK1A, EGFR, ERBB2, FABP4, FLT3, GBA, GPER1, HSPA1A, HTR2A, HTR2B, IGF1R, INSR, KDR, MIF, MMP9, NUAK1, PIK3CA, PIK3CB, PRKCA, PRKCD, PRKCE, PRKCG, PTGS2, PTPN1, SRC, TEK, XDH |
7.36465 |
|
[BP] GO:1902532 |
negative regulation of intracellular signal transduction
|
ADRA1A, BCL2, DRD2, DRD3, DUSP3, DYRK1A, ESR1, GBA, GPER1, HIF1A, HSPA1A, IGF1R, MET, MIF, MMP9, PRKCD, PTGS2, PTPN1, SRC, XDH |
7.36465 |
|
[BP] GO:0010035 |
response to inorganic substance
|
AKR1B1, APEX1, APP, AXL, BCL2, CA2, CYP1A1, CYP1A2, CYP1B1, DRD2, EGFR, FABP4, HIF1A, KDR, MMP9, PRKCD, PTGS2, SRC, TERT |
7.34848 |
|
[BP] GO:0009892 |
negative regulation of metabolic process
|
ADORA1, APEX1, APP, AR, AURKB, BCL2, CSNK2A1, CYP2D6, DNMT1, DRD2, DRD3, DRD5, DUSP3, DYRK1A, EGFR, ESR1, ESR2, ESRRA, FABP4, GBA, GPER1, HCAR2, HIF1A, HSPA1A, HTR2B, IGF1R, KDR, MET, MIF, MMP12, MMP9, NR3C1, PGR, PIK3CA, PPARA, PRKCA, PRKCD, PRKCE, PRKCG, PTGS2, PTPN1, RORC, SMAD3, SRC, TERT, TNKS, TNKS2, TRPV1, XDH |
7.31905 |
|
[BP] GO:0031328 |
positive regulation of cellular biosynthetic process
|
ADRB1, APP, AR, AURKB, DRD1, DRD2, DRD3, DRD5, EGFR, ERBB2, ESR1, ESR2, ESRRA, ESRRB, FABP3, GBA, GPER1, HIF1A, HTR2A, HTR2B, IGF1R, INSR, MET, MMP12, NR3C1, PGR, PPARA, PRKCD, PTGS2, RORC, SMAD3, SRC, TERT, TNKS, TNKS2, TOP2A, TRPV1 |
7.31676 |
|
[BP] GO:0036293 |
response to decreased oxygen levels
|
ADORA1, BCL2, CYP1A1, DRD2, HIF1A, HSD11B2, MMP2, PPARA, PRKCB, PRKCE, PTGS2, SMAD3, SRC, TEK, TERT |
7.27641 |
|
[BP] GO:0008217 |
None
|
ADORA1, ADRA1A, ADRB1, AR, DRD2, DRD3, DRD5, HSD11B2, PPARA, PTGS1, PTGS2, SMAD3 |
7.2641 |
|
[BP] GO:0032270 |
positive regulation of cellular protein metabolic process
|
ADORA1, ADRA1A, APP, AR, BCL2, CDC25B, DNMT1, DRD2, DYRK1A, EGFR, ERBB2, ESR1, F3, FLT3, GBA, GPER1, HSPA1A, HTR2A, HTR2B, INSR, KDR, MIF, MMP9, PIK3CA, PIK3CB, PRKCA, PRKCD, PRKCE, PTGS2, PTPN1, SMAD3, SRC, TEK, XDH |
7.25357 |
|
[BP] GO:0031401 |
positive regulation of protein modification process
|
ADORA1, ADRA1A, APP, AR, BCL2, CDC25B, DNMT1, DRD2, DYRK1A, EGFR, ERBB2, FLT3, GBA, GPER1, HTR2A, HTR2B, INSR, KDR, MIF, MMP9, PIK3CA, PIK3CB, PRKCA, PRKCD, PRKCE, PTGS2, PTPN1, SRC, TEK, XDH |
7.25042 |
|
[BP] GO:0032846 |
positive regulation of homeostatic process
|
AURKB, CA2, CA7, DRD1, DRD2, DRD3, EGFR, GPER1, HCAR2, HIF1A, PIK3CB, PTGS2, TNKS, TNKS2 |
7.24129 |
|
[BP] GO:0051247 |
positive regulation of protein metabolic process
|
ADORA1, ADRA1A, APP, AR, BCL2, CDC25B, CSNK2A1, DNMT1, DRD2, DYRK1A, EGFR, ERBB2, ESR1, F3, FLT3, GBA, GPER1, HSPA1A, HTR2A, HTR2B, INSR, KDR, MIF, MMP9, PIK3CA, PIK3CB, PRKCA, PRKCD, PRKCE, PTGS2, PTPN1, SMAD3, SRC, TEK, XDH |
7.23768 |
|
[BP] GO:0051272 |
positive regulation of cellular component movement
|
APP, BCL2, DRD1, EGFR, F3, GPER1, HIF1A, IGF1R, INSR, KDR, MET, MMP9, PRKCA, PRKCE, PTGS2, SMAD3, SRC, TEK, TERT |
7.2373 |
|
[BP] GO:0001932 |
regulation of protein phosphorylation
|
ADORA1, ADRA1A, APP, AR, BCL2, CDC25B, DRD1, DRD2, DUSP3, EGFR, ERBB2, FABP4, FLT3, GBA, GPER1, HTR2A, HTR2B, IGF1R, INSR, KDR, MIF, MMP9, PIK3CA, PIK3CB, PRKCA, PRKCD, PRKCE, PTGS2, PTPN1, SRC, TEK, XDH |
7.16669 |
|
[BP] GO:0070372 |
regulation of ERK1 and ERK2 cascade
|
ADRA1A, APP, DRD2, DUSP3, EGFR, ERBB2, GPER1, HTR2A, HTR2B, KDR, MIF, PRKCA, PTPN1, SRC, TEK |
7.14392 |
|
[BP] GO:0045935 |
positive regulation of nucleobase-containing compound metabolic process
|
ADRB1, APP, AR, AURKB, DNMT1, DRD1, DRD2, DRD3, DRD5, EGFR, ERBB2, ESR1, ESR2, ESRRA, ESRRB, GPER1, HIF1A, HSPA1A, HTR2A, IGF1R, INSR, MET, MMP12, NR3C1, PGR, PPARA, PRKCD, PRKCG, PTPN1, RORC, SMAD3, SRC, TERT, TNKS, TNKS2, TOP2A |
7.14114 |
|
[BP] GO:0050806 |
positive regulation of synaptic transmission
|
ADORA1, ADRA1A, APP, CA2, CA7, DRD1, DRD2, EGFR, GPER1, PRKCE, PTGS2 |
7.11085 |
|
[BP] GO:0016310 |
phosphorylation
|
APP, AURKB, AXL, BCL2, CDC25B, CDK6, CSNK2A1, DRD1, DYRK1A, EGFR, ERBB2, FLT3, HTR2B, IGF1R, INSR, KDR, MET, NUAK1, PIK3CA, PIK3CB, PIM1, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, SRC, TEK, TNKS |
7.08918 |
|
[BP] GO:0006820 |
anion transport
|
ABCB1, CA1, CA12, CA14, CA2, CA3, CA4, CA5A, CA5B, CA6, CA7, CA9, DRD2, DRD3, FABP3, PPARA, SLC22A1, SLC22A2, SLC22A3, TRPV1 |
7.01576 |
|
[BP] GO:0040017 |
positive regulation of locomotion
|
APP, BCL2, DRD1, EGFR, F3, GPER1, HIF1A, IGF1R, INSR, KDR, MET, MMP9, PRKCA, PRKCE, PTGS2, SMAD3, SRC, TEK, TERT |
7.00062 |
|
[BP] GO:0046777 |
protein autophosphorylation
|
AURKB, CSNK2A1, DYRK1A, EGFR, ERBB2, FLT3, IGF1R, INSR, KDR, PIM1, PRKCG, SRC, TEK |
6.99506 |
|
[BP] GO:0006950 |
response to stress
|
ACHE, ADORA1, ADORA3, ADRB1, AKR1B1, APEX1, APP, AXL, BCL2, CA2, CA3, CA9, CYP1A1, CYP1A2, CYP1B1, DRD1, DRD2, DRD5, EGFR, ERBB2, GBA, GPER1, HIF1A, HSD11B2, HSPA1A, HTR1A, IDO1, MIF, MMP2, MMP9, NUAK1, PIK3CA, PIK3CB, POLA1, POLB, PPARA, PRKCB, PRKCD, PRKCE, PRKCG, PTGS1, PTGS2, PTPN1, SMAD3, SRC, TEK, TERT, TOP2A, TRPV1 |
6.99497 |
|
[BP] GO:0048511 |
rhythmic process
|
AXL, BCL2, CSNK2A1, DRD2, DRD3, DYRK1A, EGFR, ESR1, HTR7, PGR, PPARA, PRKCG, RORC, SRC, TOP2A |
6.94877 |
|
[BP] GO:0043085 |
positive regulation of catalytic activity
|
ADORA1, ADRA1A, ADRB1, APP, AURKB, BCL2, CDC25B, DRD2, DRD5, EGFR, ERBB2, ESR1, F3, FLT3, GPER1, HIF1A, HSPA1A, HTR2A, HTR2B, INSR, MIF, PIK3CA, PIK3CB, PRKCD, PRKCE, PTPN1, SMAD3, SRC, TEK, TERT, TNKS, XDH |
6.86786 |
|
[BP] GO:0071495 |
cellular response to endogenous stimulus
|
AKR1B1, APEX1, APP, AR, DNMT1, DRD1, DRD5, EGFR, ERBB2, ESR1, FLT3, GPER1, IGF1R, INSR, MMP2, NR3C1, PRKCD, PRKCE, PTGS2, SMAD3, SRC, TRPV1 |
6.8442 |
|
[BP] GO:0048513 |
animal organ development
|
ACHE, ADRA1A, AR, AXL, BCL2, CA2, CACNA1C, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, EGFR, ERBB2, ESR1, ESRRA, ESRRB, FLT3, HIF1A, HSD11B1, HSD17B2, INSR, KDR, PIK3CA, POLB, PPARA, SMAD3, SRC, TEK, TYR |
6.81866 |
|
[BP] GO:0009755 |
hormone-mediated signaling pathway
|
AR, ESR1, ESR2, ESRRA, ESRRB, GPER1, NR3C1, NR3C2, PGR, PPARA, RORC, SRC |
6.7426 |
|
[BP] GO:0009636 |
response to toxic substance
|
AKR1B1, ALPL, APEX1, AXL, BCL2, CA3, CYP1A1, CYP1B1, DRD1, DRD2, DRD3, DRD5, KDR, POLB, PRKCD, PRKCE, SRC |
6.63332 |
|
[BP] GO:0001505 |
regulation of neurotransmitter levels
|
ACHE, CYP1B1, DRD1, DRD2, DRD3, EGFR, GPER1, HTR1A, INSR, PTGS2, SLC22A2, SLC22A3, SMAD3, TRPV1 |
6.60517 |
|
[BP] GO:0030522 |
intracellular receptor signaling pathway
|
AR, ESR1, ESR2, ESRRA, ESRRB, GPER1, NR3C1, PGR, PIM1, PPARA, RORC, SRC |
6.51973 |
|
[BP] GO:0032101 |
regulation of response to external stimulus
|
ADORA1, CYP19A1, DRD1, DRD2, DRD3, EGFR, ESR1, F3, FABP4, GBA, GPER1, IDO1, KDR, MET, MIF, MMP12, PPARA, PRKCA, PRKCD, PRKCG, PTGS2, SMAD3, TEK |
6.48198 |
|
[BP] GO:1901615 |
organic hydroxy compound metabolic process
|
AKR1B1, AKR1B10, ALDH2, APP, BCL2, CYP19A1, CYP1A1, CYP1B1, DAO, DRD1, DRD2, DRD3, GBA, GBA2, HIF1A, HTR1A, TYR |
6.45513 |
|
[BP] GO:0019216 |
regulation of lipid metabolic process
|
ADORA1, CYP1A1, DRD3, FABP3, FLT3, GPER1, HCAR2, HTR2A, HTR2B, PPARA, PRKCD, PRKCE, PTGS2, RORC, SRC, TEK |
6.41713 |
|
[BP] GO:0032845 |
None
|
ADORA1, BCL2, DRD2, HTR2A, HTR2B, MIF, PRKCE, SRC, TNKS, TNKS2, TRPV1 |
6.35722 |
|
[BP] GO:0007610 |
None
|
APP, BCL2, DRD1, DRD2, DRD3, DRD5, EGFR, GAA, HIF1A, HTR1A, HTR2A, HTR2B, IDO1, INSR, PPARA, PRKCE, PRKCG, PTGS2, TRPV1 |
6.33011 |
|
[BP] GO:0007187 |
None
|
ADORA1, ADRA1A, ADRB1, DRD1, DRD2, DRD3, DRD5, GPER1, HTR1A, HTR5A, HTR6, HTR7 |
6.32819 |
|
[BP] GO:0045787 |
positive regulation of cell cycle
|
APEX1, APP, AURKB, CDC25B, CYP1A1, DRD2, DRD3, DUSP3, EGFR, GPER1, INSR, MIF, PRKCA, PRKCE, SRC, TERT |
6.30198 |
|
[BP] GO:0018108 |
peptidyl-tyrosine phosphorylation
|
AXL, DYRK1A, EGFR, ERBB2, FLT3, IGF1R, INSR, KDR, MET, PRKCD, SRC, TEK |
6.25256 |
|
[BP] GO:0009968 |
negative regulation of signal transduction
|
ADRA1A, AR, BCL2, DRD2, DRD3, DUSP3, DYRK1A, EGFR, ERBB2, ESR1, ESR2, GBA, GPER1, HIF1A, HSPA1A, IGF1R, MET, MIF, MMP12, MMP9, PRKCB, PRKCD, PTGS2, PTPN1, SMAD3, SRC, TERT, XDH |
6.23621 |
|
[BP] GO:0018212 |
peptidyl-tyrosine modification
|
AXL, DYRK1A, EGFR, ERBB2, FLT3, IGF1R, INSR, KDR, MET, PRKCD, SRC, TEK |
6.18464 |
|
[BP] GO:0048871 |
multicellular organismal homeostasis
|
ADORA1, ADRB1, AKR1B1, DRD1, DRD2, GBA, HTR2A, MET, PIK3CA, TRPV1 |
6.09974 |
|
[BP] GO:0035690 |
cellular response to drug
|
AKR1B1, APEX1, AXL, CDK6, CYP1B1, DRD1, EGFR, KDR, NR3C1, PRKCD, PRKCE, PTGS2, SRC, TRPV1 |
6.09747 |
|
[BP] GO:1901564 |
organonitrogen compound metabolic process
|
ABCG2, ACHE, AKR1B1, ALPI, ALPL, AOX1, APP, AR, AURKB, AXL, BACE1, BCL2, CDC25B, CDK6, CSNK2A1, CYP1A1, CYP1A2, CYP2D6, DAO, DRD1, DRD2, DRD3, DUSP3, DYRK1A, EGFR, ERBB2, ESR1, F3, FLT3, FUCA1, FUT7, GBA, GBA2, GLO1, HIF1A, HSPA1A, HTR1A, HTR2B, IDO1, IGF1R, INSR, KDR, MET, MMP1, MMP12, MMP2, MMP9, NUAK1, PIK3CA, PIM1, POLB, PPARA, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, PTGS2, PTPN1, SMAD3, SRC, TEK, TNKS, TNKS2, TOP2A, TYR, XDH |
6.07925 |
|
[BP] GO:1901568 |
fatty acid derivative metabolic process
|
ALOX5, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, CYP2D6, MIF, PTGS1, PTGS2, TBXAS1 |
6.05647 |
|
[BP] GO:0007188 |
None
|
ADORA1, ADRA1A, ADRB1, DRD1, DRD2, DRD3, DRD5, GPER1, HTR1A, HTR5A, HTR7 |
6.02922 |
|
[BP] GO:0070374 |
positive regulation of ERK1 and ERK2 cascade
|
ADRA1A, APP, DRD2, EGFR, GPER1, HTR2A, HTR2B, KDR, MIF, PRKCA, SRC, TEK |
5.99843 |
|
[BP] GO:0007210 |
None
|
HTR1A, HTR2A, HTR2B, HTR5A, HTR6, HTR7 |
5.98285 |
|
[BP] GO:0098664 |
None
|
HTR1A, HTR2A, HTR2B, HTR5A, HTR6, HTR7 |
5.98285 |
|
[BP] GO:0043405 |
regulation of MAP kinase activity
|
ADORA1, DUSP3, EGFR, ERBB2, FLT3, GBA, HTR2A, HTR2B, IGF1R, INSR, MIF, PIK3CB, PRKCD, PTPN1, SRC |
5.97855 |
|
[BP] GO:0009894 |
regulation of catabolic process
|
ADORA1, APEX1, BCL2, CSNK2A1, EGFR, ESRRB, GBA, HCAR2, HIF1A, HSPA1A, HTR2A, HTR2B, INSR, KDR, MET, PIK3CA, PIK3CB, PPARA, PRKCA, PRKCD, PRKCE, PRKCG, PTPN1, SMAD3 |
5.96277 |
|
[BP] GO:0045834 |
positive regulation of lipid metabolic process
|
FABP3, FLT3, HTR2A, HTR2B, PPARA, PRKCD, PRKCE, PTGS2, SRC, TEK |
5.95684 |
|
[BP] GO:0044057 |
None
|
ADORA1, ADORA3, ADRA1A, ADRB1, CACNA1C, DRD2, DRD3, EGFR, GAA, GBA, GPER1, GPR35, HCAR2, HTR2A, PRKCA, PTGS2, SMAD3, TRPV1 |
5.86468 |
|
[BP] GO:1903727 |
positive regulation of phospholipid metabolic process
|
FABP3, FLT3, HTR2A, HTR2B, PRKCD, SRC, TEK |
5.85258 |
|
[BP] GO:0018105 |
peptidyl-serine phosphorylation
|
AURKB, BCL2, DRD1, DYRK1A, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, SRC, TNKS |
5.80793 |
|
[BP] GO:0008283 |
cell proliferation
|
ABCB1, ACHE, AR, AURKB, BCL2, CYP1A1, EGFR, ERBB2, ESR1, FLT3, HTR1A, MET, MIF, PIK3CB, PIM1, POLA1, PRKCD, SRC, TEK, TYR |
5.78252 |
|
[BP] GO:0045913 |
None
|
ESRRB, GPER1, HIF1A, HTR2A, INSR, PPARA, PRKCE, SRC |
5.75354 |
|
[BP] GO:0031324 |
negative regulation of cellular metabolic process
|
APEX1, APP, AR, AURKB, BCL2, CSNK2A1, CYP2D6, DNMT1, DRD2, DRD3, DUSP3, DYRK1A, ESR1, ESR2, ESRRA, FABP4, GBA, GPER1, HIF1A, HSPA1A, HTR2B, IGF1R, MET, MIF, MMP12, MMP9, NR3C1, PIK3CA, PPARA, PRKCA, PRKCD, PRKCE, PRKCG, PTGS2, PTPN1, RORC, SMAD3, SRC, TERT, TNKS, TNKS2, TRPV1, XDH |
5.67322 |
|
[BP] GO:0001676 |
long-chain fatty acid metabolic process
|
CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, CYP2D6, PTGS1, PTGS2, TBXAS1 |
5.61998 |
|
[BP] GO:0032787 |
None
|
ALOX5, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, CYP2D6, FABP3, GBA2, GLO1, HIF1A, IDO1, MIF, PPARA, PTGS1, PTGS2, TBXAS1 |
5.61222 |
|
[BP] GO:0080090 |
regulation of primary metabolic process
|
ADORA1, ADORA3, ADRA1A, ADRB1, APEX1, APP, AR, AURKB, BCL2, CA9, CDC25B, CSNK2A1, CYP1A1, CYP1B1, DNMT1, DRD1, DRD2, DRD3, DRD5, DUSP3, DYRK1A, EGFR, ERBB2, ESR1, ESR2, ESRRA, ESRRB, F3, FABP3, FABP4, FLT3, GBA, GLO1, GPER1, HCAR2, HIF1A, HSPA1A, HTR1A, HTR2A, HTR2B, IGF1R, INSR, KDR, MET, MIF, MMP12, MMP9, NR3C1, NR3C2, NUAK1, PGR, PIK3CA, PIK3CB, PIM1, POLA1, PPARA, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, PTGS2, PTPN1, RORC, SMAD3, SRC, TEK, TERT, TNKS, TNKS2, TOP2A, TRPV1, XDH |
5.59942 |
|
[BP] GO:0001775 |
cell activation
|
ALOX5, APP, AXL, BCL2, EGFR, FLT3, FUCA1, FUT7, GAA, HSPA1A, MGAM, MIF, MMP9, PIK3CA, PIK3CB, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, RORC, SMAD3, SRC, TRPV1 |
5.59731 |
|
[BP] GO:0090087 |
None
|
ACHE, ADORA1, APP, CA2, CACNA1C, DRD2, DRD3, EGFR, ERBB2, GPER1, HCAR2, HIF1A, HTR2B, MIF, MMP12, PRKCA, PRKCD, PRKCE, PTGS2, PTPN1, SMAD3, SRC |
5.59415 |
|
[BP] GO:0043269 |
regulation of ion transport
|
ABCB1, ADORA1, APP, BCL2, CA2, CA7, CACNA1C, DRD1, DRD2, DRD3, GPER1, GPR35, HTR1A, HTR2A, MIF, MMP9, PRKCD, PRKCE, PTGS2 |
5.57348 |
|
[BP] GO:0019222 |
regulation of metabolic process
|
ACHE, ADORA1, ADORA3, ADRA1A, ADRB1, APEX1, APP, AR, AURKB, BCL2, CA9, CDC25B, CDK6, CSNK2A1, CYP1A1, CYP1A2, CYP1B1, CYP2D6, DNMT1, DRD1, DRD2, DRD3, DRD5, DUSP3, DYRK1A, EGFR, ERBB2, ESR1, ESR2, ESRRA, ESRRB, F3, FABP3, FABP4, FLT3, GBA, GLO1, GPER1, HCAR2, HIF1A, HSPA1A, HTR1A, HTR2A, HTR2B, IGF1R, INSR, KDR, MET, MIF, MMP12, MMP9, NR3C1, NR3C2, NUAK1, PGR, PIK3CA, PIK3CB, PIM1, POLA1, PPARA, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, PTGS2, PTPN1, RORC, SMAD3, SRC, TEK, TERT, TNKS, TNKS2, TOP2A, TRPV1, XDH |
5.55299 |
|
[BP] GO:0048545 |
response to steroid hormone
|
ALPL, AR, BCL2, CA2, EGFR, FLT3, GBA, GPER1, HSD11B2, NR3C1, PTGS2, SRC |
5.54264 |
|
[BP] GO:0006939 |
None
|
ADRA1A, DRD1, DRD2, HTR2A, HTR2B, HTR7, TRPV1 |
5.53879 |
|
[BP] GO:0042310 |
None
|
ADRA1A, DRD5, HTR1A, HTR2A, HTR2B, HTR7 |
5.49729 |
|
[BP] GO:0006811 |
None
|
ABCB1, ADRA1A, CA1, CA12, CA14, CA2, CA3, CA4, CA5A, CA5B, CA6, CA7, CA9, CACNA1C, DRD1, DRD2, DRD3, FABP3, HTR2A, HTR2B, PPARA, PRKCB, PRKCE, SLC22A1, SLC22A2, SLC22A3, SLC47A1, TRPV1 |
5.43977 |
|
[BP] GO:0048856 |
anatomical structure development
|
ACHE, ADORA1, ADRA1A, AKR1B1, ALPL, APP, AR, AXL, BCL2, CA2, CACNA1C, CDK6, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, DRD1, DRD2, DUSP3, DYRK1A, EGFR, ERBB2, ESR1, ESRRA, ESRRB, FLT3, GAA, GBA2, HIF1A, HSD11B1, HSD17B2, HTR5A, INSR, KDR, MMP9, PGR, PIK3CA, PIM1, POLB, PPARA, PTGS2, RORC, SIGMAR1, SMAD3, SRC, TEK, TYR |
5.43977 |
|
[BP] GO:0051047 |
None
|
ACHE, ADORA1, CYP19A1, DRD2, DRD3, EGFR, GPER1, HCAR2, HIF1A, HTR2B, MIF, MMP12, PRKCE, SRC, TRPV1 |
5.36358 |
|
[BP] GO:0018209 |
peptidyl-serine modification
|
AURKB, BCL2, DRD1, DYRK1A, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, SRC, TNKS |
5.35821 |
|
[BP] GO:0031323 |
regulation of cellular metabolic process
|
ACHE, ADORA1, ADORA3, ADRA1A, ADRB1, APEX1, APP, AR, AURKB, BCL2, CA9, CDC25B, CSNK2A1, CYP1B1, CYP2D6, DNMT1, DRD1, DRD2, DRD3, DRD5, DUSP3, DYRK1A, EGFR, ERBB2, ESR1, ESR2, ESRRA, ESRRB, F3, FABP3, FABP4, FLT3, GBA, GLO1, GPER1, HIF1A, HSPA1A, HTR1A, HTR2A, HTR2B, IGF1R, INSR, KDR, MET, MIF, MMP12, MMP9, NR3C1, NR3C2, NUAK1, PGR, PIK3CA, PIK3CB, PIM1, POLA1, PPARA, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, PTGS2, PTPN1, RORC, SMAD3, SRC, TEK, TERT, TNKS, TNKS2, TOP2A, TRPV1, XDH |
5.34752 |
|
[BP] GO:0050678 |
None
|
AR, CDK6, EGFR, ERBB2, F3, HIF1A, HTR2B, KDR, MMP12, PGR, PRKCA, SMAD3, TEK, XDH |
5.33063 |
|
[BP] GO:0001659 |
None
|
ADORA1, ADRB1, DRD1, DRD2, HTR2A, TRPV1 |
5.33063 |
|
[BP] GO:0014065 |
phosphatidylinositol 3-kinase signaling
|
ERBB2, HTR2A, HTR2B, IGF1R, PIK3CA, PIK3CB |
5.33063 |
|
[BP] GO:0018958 |
None
|
AKR1B1, BCL2, DAO, DRD1, DRD2, DRD3, HTR1A, TYR |
5.3226 |
|
[BP] GO:0030168 |
platelet activation
|
AXL, PIK3CA, PIK3CB, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, SRC |
5.30088 |
|
[BP] GO:0051171 |
regulation of nitrogen compound metabolic process
|
ADORA1, ADORA3, ADRA1A, ADRB1, APEX1, APP, AR, AURKB, BCL2, CA9, CDC25B, CSNK2A1, CYP1B1, DNMT1, DRD1, DRD2, DRD3, DRD5, DUSP3, DYRK1A, EGFR, ERBB2, ESR1, ESR2, ESRRA, ESRRB, F3, FABP3, FABP4, FLT3, GBA, GLO1, GPER1, HIF1A, HSPA1A, HTR1A, HTR2A, HTR2B, IGF1R, INSR, KDR, MET, MIF, MMP12, MMP9, NR3C1, NR3C2, NUAK1, PGR, PIK3CA, PIK3CB, PIM1, POLA1, PPARA, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, PTGS2, PTPN1, RORC, SMAD3, SRC, TEK, TERT, TNKS, TNKS2, TOP2A, TRPV1, XDH |
5.25628 |
|
[BP] GO:1900542 |
None
|
ADRB1, DRD1, DRD2, DRD3, DRD5, ESRRB, GPER1, HIF1A, HTR2A, INSR, PPARA, PRKCA |
5.25497 |
|
[BP] GO:0032228 |
regulation of synaptic transmission, GABAergic
|
ADORA1, ADRA1A, CA2, CA7, DRD2, PRKCE |
5.25117 |
|
[BP] GO:0044092 |
negative regulation of molecular function
|
ADORA3, APP, AURKB, CSNK2A1, CYP1B1, CYP2D6, DRD2, DRD3, DRD5, DUSP3, ESR1, FABP4, GBA, GPR35, IGF1R, MET, MMP9, PIM1, PPARA, PRKCA, PRKCD, PRKCE, PTGS2, PTPN1, SRC, TNKS |
5.24686 |
|
[BP] GO:0009698 |
phenylpropanoid metabolic process
|
CYP1A1, CYP2A13, CYP2A6, CYP2D6 |
5.24592 |
|
[BP] GO:0009804 |
coumarin metabolic process
|
CYP1A1, CYP2A13, CYP2A6, CYP2D6 |
5.24592 |
|
[BP] GO:0019932 |
second-messenger-mediated signaling
|
ADRA1A, ADRB1, CACNA1C, DRD1, DRD2, DRD3, DRD5, EGFR, GPER1, HTR2B, HTR5A, KDR |
5.24449 |
|
[BP] GO:0051130 |
positive regulation of cellular component organization
|
APP, AR, AURKB, AXL, BCL2, DNMT1, DRD2, DRD3, ESR1, GBA, GPER1, HIF1A, HSPA1A, IGF1R, INSR, KDR, MET, MMP1, MMP9, PRKCD, PRKCE, SMAD3, SRC, TEK, TNKS, TNKS2 |
5.21827 |
|
[BP] GO:1904951 |
positive regulation of establishment of protein localization
|
ACHE, APP, BCL2, DRD2, EGFR, ERBB2, GPER1, HCAR2, HIF1A, HTR2B, MIF, MMP12, PRKCD, PRKCE, PTGS2, SMAD3, SRC |
5.21529 |
|
[BP] GO:0071417 |
cellular response to organonitrogen compound
|
AKR1B1, APEX1, APP, DNMT1, DRD1, DRD5, EGFR, GPER1, IGF1R, INSR, MMP2, PRKCD, PTGS2, SRC, TRPV1 |
5.20689 |
|
[BP] GO:0051897 |
positive regulation of protein kinase B signaling
|
AXL, EGFR, ERBB2, F3, INSR, MET, PIK3CA, PIK3CB, SRC, TEK |
5.16156 |
|
[BP] GO:0009987 |
cellular process
|
ABCB1, ABCG2, ACHE, ADORA1, ADORA3, ADRA1A, ADRB1, AKR1B1, AKR1B10, ALDH2, ALOX5, ALPI, ALPL, AOX1, APEX1, APP, AR, AURKB, AXL, BACE1, BCL2, CA1, CA12, CA2, CA3, CA4, CA5A, CA5B, CA6, CA7, CA9, CACNA1C, CDC25B, CDK6, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, CYP2D6, DAO, DNMT1, DRD1, DRD2, DRD3, DRD5, DUSP3, DYRK1A, EGFR, ERBB2, ESR1, ESR2, ESRRA, ESRRB, F3, FABP3, FABP4, FLT3, FUCA1, FUT7, GAA, GBA, GBA2, GLO1, GPER1, GPR35, HCAR2, HIF1A, HSD17B1, HSD17B2, HSPA1A, HTR1A, HTR2A, HTR2B, HTR5A, HTR6, HTR7, IDO1, IGF1R, INSR, KDR, MET, MGAM, MIF, MMP1, MMP12, MMP2, MMP9, NQO2, NR3C1, NR3C2, NUAK1, PGR, PIK3CA, PIK3CB, PIM1, POLA1, POLB, PPARA, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, PTGS1, PTGS2, PTPN1, RORC, SIGMAR1, SLC22A1, SLC22A2, SMAD3, SRC, TBXAS1, TEK, TERT, TNKS, TNKS2, TOP2A, TRPV1, TYR, XDH |
5.15718 |
|
[BP] GO:0006979 |
response to oxidative stress
|
AKR1B1, APEX1, APP, AXL, BCL2, CA3, CYP1B1, EGFR, HSPA1A, MMP9, PRKCD, PTGS1, PTGS2, SRC |
5.14949 |
|
[BP] GO:0006140 |
None
|
ADRB1, DRD1, DRD2, DRD3, DRD5, ESRRB, GPER1, HIF1A, HTR2A, INSR, PPARA, PRKCA |
5.13603 |
|
[BP] GO:0032880 |
regulation of protein localization
|
ACHE, APP, AR, BCL2, CACNA1C, CSNK2A1, DRD2, DRD3, EGFR, ERBB2, GPER1, HCAR2, HIF1A, HTR2B, MIF, MMP12, PRKCA, PRKCD, PRKCE, PTGS2, PTPN1, SMAD3, SRC, TERT |
5.09534 |
|
[BP] GO:0031960 |
response to corticosteroid
|
ALPL, BCL2, EGFR, FLT3, GBA, GPER1, HSD11B2, NR3C1, PTGS2, SRC |
5.08941 |
|
[BP] GO:0016137 |
None
|
AKR1B1, AKR1B10, FUCA1, GBA, GBA2 |
5.08207 |
|
[BP] GO:0017144 |
drug metabolic process
|
ACHE, AKR1B1, AKR1B10, ALDH2, AOX1, CYP1A1, CYP1A2, CYP1B1, CYP2A6, CYP2D6, DAO, DRD1, DRD2, DRD3, EGFR, HSPA1A, IDO1 |
5.07458 |
|
[BP] GO:0018193 |
peptidyl-amino acid modification
|
AURKB, AXL, BCL2, CSNK2A1, DRD1, DYRK1A, EGFR, ERBB2, FLT3, IGF1R, INSR, KDR, MET, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, SRC, TEK, TNKS, TOP2A |
5.06781 |
|
[BP] GO:1901652 |
response to peptide
|
AKR1B1, APEX1, APP, FABP3, GPER1, HSD11B2, IGF1R, INSR, PPARA, PRKCD, PTGS2, SRC, TEK, TRPV1 |
5.06781 |
|
[BP] GO:0006631 |
fatty acid metabolic process
|
ALOX5, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, CYP2D6, FABP3, MIF, PPARA, PTGS1, PTGS2, TBXAS1 |
5.05658 |
|
[BP] GO:0006367 |
transcription initiation from RNA polymerase II promoter
|
AR, ESR1, ESR2, ESRRA, ESRRB, NR3C1, NR3C2, PGR, PPARA, RORC |
4.9691 |
|
[BP] GO:0003008 |
None
|
ADORA1, ADRA1A, ADRB1, AKR1B1, APP, BCL2, CYP1B1, DRD1, DRD2, DRD3, DRD5, EGFR, GAA, GPER1, HIF1A, HSD11B2, HTR1A, HTR2A, HTR2B, HTR7, INSR, PIK3CA, PRKCG, PTGS2, SRC, TEK, TRPV1, TYR |
4.93023 |
|
[BP] GO:0070201 |
None
|
ACHE, APP, BCL2, CACNA1C, DRD2, DRD3, EGFR, ERBB2, GPER1, HCAR2, HIF1A, HTR2B, MIF, MMP12, PRKCA, PRKCD, PRKCE, PTGS2, PTPN1, SMAD3, SRC |
4.89166 |
|
[BP] GO:0051222 |
positive regulation of protein transport
|
ACHE, APP, DRD2, EGFR, ERBB2, GPER1, HCAR2, HIF1A, HTR2B, MIF, MMP12, PRKCD, PRKCE, PTGS2, SMAD3, SRC |
4.89034 |
|
[BP] GO:0002793 |
None
|
ACHE, ADORA1, DRD2, EGFR, GPER1, HCAR2, HIF1A, HTR2B, MIF, MMP12, PRKCE, SRC |
4.88978 |
|
[BP] GO:0010634 |
positive regulation of epithelial cell migration
|
HIF1A, KDR, MET, MMP9, PRKCA, PRKCE, PTGS2, SRC, TEK |
4.86615 |
|
[BP] GO:0010638 |
positive regulation of organelle organization
|
AURKB, BCL2, DNMT1, DRD3, GBA, GPER1, HIF1A, HSPA1A, INSR, KDR, MET, MMP9, PRKCE, SMAD3, SRC, TEK, TNKS, TNKS2 |
4.85088 |
|
[BP] GO:0019933 |
None
|
ADRA1A, ADRB1, DRD1, DRD2, DRD3, DRD5, GPER1, HTR5A |
4.84722 |
|
[BP] GO:1901699 |
cellular response to nitrogen compound
|
AKR1B1, APEX1, APP, DNMT1, DRD1, DRD5, EGFR, GPER1, IGF1R, INSR, MMP2, PRKCD, PTGS2, SRC, TRPV1 |
4.79336 |
|
[BP] GO:0090066 |
None
|
ADORA1, ADRA1A, ADRB1, DRD1, DRD5, EGFR, GPER1, HTR1A, HTR2A, HTR2B, HTR7, PRKCD, PRKCE, PTGS2 |
4.79336 |
|
[BP] GO:2000377 |
regulation of reactive oxygen species metabolic process
|
BCL2, CYP1B1, EGFR, HIF1A, INSR, PRKCD, PTGS2, SMAD3, TRPV1, XDH |
4.76642 |
|
[BP] GO:0046883 |
regulation of hormone secretion
|
ADORA1, CACNA1C, CYP19A1, DRD2, EGFR, GPER1, HCAR2, HIF1A, HTR1A, HTR2A, PRKCA, PRKCE |
4.75846 |
|
[BP] GO:0019373 |
epoxygenase P450 pathway
|
CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6 |
4.74476 |
|
[BP] GO:0050805 |
negative regulation of synaptic transmission
|
ACHE, ADORA1, DRD1, DRD2, DRD5, HTR2A, PTGS2 |
4.74184 |
|
[BP] GO:0060402 |
None
|
ADRA1A, CACNA1C, DRD2, HTR2A, HTR2B, PRKCE, TRPV1 |
4.74184 |
|
[BP] GO:0006855 |
None
|
ABCB1, ABCG2, SLC22A1, SLC22A2, SLC22A3, SLC47A1, SLC47A2 |
4.74184 |
|
[BP] GO:0031348 |
negative regulation of defense response
|
ADORA1, CYP19A1, DRD2, GBA, GPER1, MMP12, PPARA, PRKCD, SMAD3, TEK |
4.73042 |
|
[BP] GO:2001243 |
negative regulation of intrinsic apoptotic signaling pathway
|
BCL2, HIF1A, HSPA1A, MIF, MMP9, PTGS2, PTPN1, SRC |
4.72051 |
|
[BP] GO:0051726 |
regulation of cell cycle
|
APEX1, APP, AURKB, BCL2, CDC25B, CDK6, CSNK2A1, CYP1A1, DRD2, DRD3, DUSP3, EGFR, GPER1, HSPA1A, INSR, MIF, PIM1, PRKCA, PRKCE, PTGS2, SMAD3, SRC, TERT, TNKS, TOP2A |
4.71689 |
|
[BP] GO:0043549 |
regulation of kinase activity
|
ADORA1, APP, CDC25B, DRD2, DUSP3, EGFR, ERBB2, FABP4, FLT3, GBA, HTR2A, HTR2B, IGF1R, INSR, MIF, PIK3CA, PIK3CB, PRKCD, PTPN1, SRC, TEK |
4.70809 |
|
[BP] GO:0007169 |
transmembrane receptor protein tyrosine kinase signaling pathway
|
AXL, EGFR, ERBB2, FLT3, IGF1R, INSR, KDR, MET, MMP2, MMP9, PIK3CA, PIK3CB, PRKCA, PTPN1, SRC, TEK |
4.70613 |
|
[BP] GO:0032268 |
regulation of cellular protein metabolic process
|
ADORA1, ADRA1A, APP, AR, BCL2, CDC25B, CSNK2A1, DNMT1, DRD1, DRD2, DUSP3, DYRK1A, EGFR, ERBB2, ESR1, F3, FABP4, FLT3, GBA, GPER1, HSPA1A, HTR2A, HTR2B, IGF1R, INSR, KDR, MIF, MMP9, NUAK1, PIK3CA, PIK3CB, PRKCA, PRKCD, PRKCE, PRKCG, PTGS2, PTPN1, SMAD3, SRC, TEK, XDH |
4.64996 |
|
[BP] GO:0050679 |
None
|
AR, EGFR, ERBB2, F3, HIF1A, HTR2B, KDR, MMP12, PRKCA, TEK |
4.64707 |
|
[BP] GO:1904018 |
positive regulation of vasculature development
|
CYP1B1, F3, GPER1, HIF1A, KDR, PRKCA, PRKCB, PTGS2, TEK, TERT |
4.64707 |
|
[BP] GO:0002682 |
regulation of immune system process
|
ADORA1, APP, AXL, BCL2, CA2, CDK6, CYP19A1, DRD2, DUSP3, ERBB2, ESR1, ESRRA, GPER1, HCAR2, HIF1A, HSPA1A, IDO1, MIF, MMP12, MMP2, PIK3CA, PIK3CB, PRKCA, PRKCB, PRKCD, PRKCE, PTPN1, SMAD3, SRC |
4.64475 |
|
[BP] GO:0051223 |
None
|
ACHE, APP, CACNA1C, DRD2, DRD3, EGFR, ERBB2, GPER1, HCAR2, HIF1A, HTR2B, MIF, MMP12, PRKCA, PRKCD, PRKCE, PTGS2, PTPN1, SMAD3, SRC |
4.64475 |
|
[BP] GO:0051338 |
regulation of transferase activity
|
ADORA1, APP, AURKB, CDC25B, DRD2, DUSP3, EGFR, ERBB2, FABP4, FLT3, GBA, HTR2A, HTR2B, IGF1R, INSR, MIF, PIK3CA, PIK3CB, PRKCD, PTPN1, SRC, TEK, TNKS |
4.63807 |
|
[BP] GO:0050890 |
None
|
ADORA1, APP, DRD1, DRD2, DRD3, DRD5, EGFR, HIF1A, HTR2A, INSR, PRKCG, PTGS2 |
4.62723 |
|
[BP] GO:0040014 |
regulation of multicellular organism growth
|
ADRB1, APP, BCL2, DRD2, DRD3, PIK3CA, TNKS2 |
4.62124 |
|
[BP] GO:0031347 |
regulation of defense response
|
ADORA1, CYP19A1, DRD2, EGFR, ESR1, FABP4, GBA, GPER1, HSPA1A, IDO1, MMP12, MMP2, PPARA, PRKCD, PRKCE, PTGS2, PTPN1, SMAD3, SRC, TEK |
4.6066 |
|
[BP] GO:0045776 |
None
|
ADORA1, ADRB1, DRD2, DRD3, DRD5, PPARA |
4.59488 |
|
[BP] GO:0045859 |
regulation of protein kinase activity
|
ADORA1, APP, CDC25B, DRD2, DUSP3, EGFR, ERBB2, FABP4, FLT3, GBA, HTR2A, HTR2B, IGF1R, INSR, MIF, PIK3CA, PIK3CB, PRKCD, PTPN1, SRC |
4.59196 |
|
[BP] GO:0019935 |
None
|
ADRA1A, ADRB1, DRD1, DRD2, DRD3, DRD5, GPER1, HTR5A |
4.56995 |
|
[BP] GO:0009611 |
response to wounding
|
ACHE, ADORA3, BCL2, CYP1A1, DRD2, DRD5, EGFR, ERBB2, PPARA, SMAD3 |
4.56995 |
|
[BP] GO:0007154 |
None
|
ADORA1, ADRA1A, ADRB1, AR, AXL, BCL2, CACNA1C, DRD1, DRD2, DRD3, DRD5, ESR2, GBA, HTR2A, HTR6, HTR7, PGR, PRKCG, PTGS2, TEK, TRPV1 |
4.56322 |
|
[BP] GO:0002791 |
None
|
ACHE, ADORA1, CACNA1C, DRD2, DRD3, EGFR, GPER1, HCAR2, HIF1A, HTR2B, MIF, MMP12, PRKCA, PRKCE, SRC |
4.53104 |
|
[BP] GO:0032102 |
negative regulation of response to external stimulus
|
ADORA1, CYP19A1, DRD1, DRD2, DRD3, GBA, GPER1, MIF, PPARA, PRKCD, SMAD3, TEK |
4.52167 |
|
[BP] GO:0009056 |
catabolic process
|
ACHE, ADORA1, AKR1B10, ALDH2, AOX1, AURKB, BACE1, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A6, CYP2D6, DAO, FABP3, FABP4, FUCA1, FUT7, GAA, GBA, GBA2, HSPA1A, IDO1, MGAM, MMP1, MMP12, MMP2, MMP9, PIK3CB, SRC, XDH |
4.51997 |
|
[BP] GO:0097164 |
None
|
ACHE, AKR1B1, AKR1B10, CSNK2A1, DAO, DRD1, DRD2, DRD3, GBA, HTR1A |
4.51003 |
|
[BP] GO:0043271 |
negative regulation of ion transport
|
ADORA1, BCL2, DRD2, DRD3, GPR35, HTR2A, MMP9, PRKCE, PTGS2 |
4.47357 |
|
[BP] GO:0007568 |
aging
|
ADRA1A, APEX1, AURKB, BCL2, CYP1A1, HTR2A, MIF, POLB, PRKCD, PTGS2, TERT |
4.47322 |
|
[BP] GO:0007346 |
regulation of mitotic cell cycle
|
APEX1, APP, AURKB, BCL2, CDC25B, CDK6, CYP1A1, DRD3, DUSP3, EGFR, HSPA1A, INSR, PIM1, PRKCA, SMAD3, TERT, TNKS, TOP2A |
4.46717 |
|
[BP] GO:0042445 |
hormone metabolic process
|
ACHE, AKR1B1, CYP19A1, CYP1A1, CYP1B1, ESR1, HSD11B1, HSD11B2, HSD17B1, HSD17B2 |
4.45232 |
|
[BP] GO:0050793 |
regulation of developmental process
|
ADRB1, APP, AR, AXL, BCL2, CA2, CDK6, CYP1B1, DRD2, DRD3, EGFR, ERBB2, ESR1, ESRRA, ESRRB, F3, GPER1, HIF1A, HTR2A, IDO1, INSR, KDR, MIF, NUAK1, PIK3CA, PIM1, PPARA, PRKCA, PRKCB, PTGS2, RORC, SMAD3, SRC, TEK, TERT, TNKS2, TRPV1, XDH |
4.45232 |
|
[BP] GO:0051046 |
None
|
ACHE, ADORA1, CACNA1C, CYP19A1, DRD2, DRD3, EGFR, GPER1, HCAR2, HIF1A, HTR1A, HTR2A, HTR2B, MIF, MMP12, PRKCA, PRKCE, SRC, TRPV1 |
4.44945 |
|
[BP] GO:0051480 |
regulation of cytosolic calcium ion concentration
|
ADRA1A, CACNA1C, DRD1, DRD2, ESR1, GPER1, GPR35, HTR2A, HTR2B, PRKCE, SMAD3, TRPV1 |
4.43663 |
|
[BP] GO:1903725 |
regulation of phospholipid metabolic process
|
FABP3, FLT3, HTR2A, HTR2B, PRKCD, SRC, TEK |
4.43241 |
|
[BP] GO:0007189 |
None
|
ADRA1A, ADRB1, DRD1, DRD2, DRD3, DRD5, GPER1 |
4.43241 |
|
[BP] GO:0050714 |
None
|
ACHE, DRD2, EGFR, GPER1, HCAR2, HIF1A, HTR2B, MIF, MMP12, PRKCE, SRC |
4.4136 |
|
[BP] GO:0007611 |
None
|
APP, DRD1, DRD2, DRD3, DRD5, EGFR, HIF1A, HTR2A, INSR, PRKCG, PTGS2 |
4.4136 |
|
[BP] GO:0045931 |
positive regulation of mitotic cell cycle
|
APEX1, APP, CDC25B, CYP1A1, DRD3, DUSP3, INSR, PRKCA, TERT |
4.41317 |
|
[BP] GO:0009410 |
None
|
DRD1, DRD2, DRD3, DRD5, EGFR, GBA, NR3C1, PRKCE, PRKCG |
4.36393 |
|
[BP] GO:0060255 |
regulation of macromolecule metabolic process
|
ACHE, ADORA1, ADORA3, ADRA1A, APEX1, APP, AR, AURKB, BCL2, CA9, CDC25B, CDK6, CSNK2A1, CYP1A2, CYP1B1, DNMT1, DRD1, DRD2, DRD3, DUSP3, DYRK1A, EGFR, ERBB2, ESR1, ESR2, ESRRA, ESRRB, F3, FABP4, FLT3, GBA, GLO1, GPER1, HIF1A, HSPA1A, HTR2A, HTR2B, IGF1R, INSR, KDR, MET, MIF, MMP12, MMP9, NR3C1, NR3C2, NUAK1, PGR, PIK3CA, PIK3CB, PIM1, POLA1, PPARA, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, PTGS2, PTPN1, RORC, SMAD3, SRC, TEK, TERT, TNKS, TNKS2, TOP2A, TRPV1, XDH |
4.34616 |
|
[BP] GO:0034614 |
cellular response to reactive oxygen species
|
AKR1B1, APEX1, AXL, CYP1B1, EGFR, MMP9, PRKCD, SRC |
4.34402 |
|
[BP] GO:0015893 |
None
|
ABCB1, ABCG2, CA2, DRD1, SLC22A1, SLC22A2, SLC22A3, SLC47A1, SLC47A2 |
4.32049 |
|
[BP] GO:0060401 |
None
|
ADRA1A, CACNA1C, DRD2, HTR2A, HTR2B, PRKCE, TRPV1 |
4.28338 |
|
[BP] GO:1903530 |
regulation of secretion by cell
|
ACHE, ADORA1, CACNA1C, CYP19A1, DRD2, DRD3, EGFR, GPER1, HCAR2, HIF1A, HTR1A, HTR2A, HTR2B, MIF, MMP12, PRKCA, PRKCE, SRC |
4.27906 |
|
[BP] GO:0051347 |
positive regulation of transferase activity
|
ADORA1, AURKB, CDC25B, DRD2, EGFR, ERBB2, FLT3, HTR2A, HTR2B, INSR, MIF, PIK3CA, PIK3CB, PRKCD, PTPN1, SRC, TEK, TNKS |
4.25334 |
|
[BP] GO:0015872 |
None
|
DRD1, SLC22A1, SLC22A2, SLC22A3 |
4.22927 |
|
[BP] GO:0033674 |
positive regulation of kinase activity
|
ADORA1, CDC25B, DRD2, EGFR, ERBB2, FLT3, HTR2A, HTR2B, INSR, MIF, PIK3CA, PIK3CB, PRKCD, PTPN1, SRC, TEK |
4.22824 |
|
[BP] GO:0018107 |
peptidyl-threonine phosphorylation
|
BCL2, CSNK2A1, DYRK1A, PRKCA, PRKCB, PRKCD, TNKS |
4.21833 |
|
[BP] GO:0030518 |
intracellular steroid hormone receptor signaling pathway
|
AR, ESR1, ESR2, GPER1, NR3C1, PGR, SRC |
4.21833 |
|
[BP] GO:0051282 |
None
|
CACNA1C, DRD1, DRD2, GPER1, HTR2A, HTR2B, PRKCE, TRPV1 |
4.20988 |
|
[BP] GO:0007204 |
positive regulation of cytosolic calcium ion concentration
|
ADRA1A, CACNA1C, DRD1, DRD2, ESR1, GPER1, GPR35, HTR2A, HTR2B, PRKCE, TRPV1 |
4.208 |
|
[BP] GO:0045766 |
positive regulation of angiogenesis
|
CYP1B1, F3, HIF1A, KDR, PRKCA, PRKCB, PTGS2, TEK, TERT |
4.19289 |
|
[BP] GO:0006805 |
xenobiotic metabolic process
|
CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2D6, NQO2, PTGS1, RORC |
4.1853 |
|
[BP] GO:0008610 |
lipid biosynthetic process
|
ACHE, AKR1B1, ALPI, CSNK2A1, CYP19A1, CYP1A1, GBA, HSD11B1, HSD11B2, HSD17B1, HSD17B2, MIF, PIK3CA, PIK3CB, PTGS1, PTGS2 |
4.1853 |
|
[BP] GO:0051172 |
None
|
APEX1, APP, AR, AURKB, CSNK2A1, DNMT1, DRD2, DRD3, DUSP3, DYRK1A, EGFR, ESR1, ESR2, ESRRA, FABP4, GBA, GPER1, HSPA1A, IGF1R, MIF, MMP12, MMP9, NR3C1, PPARA, PRKCA, PRKCD, PRKCE, PRKCG, PTGS2, PTPN1, RORC, SMAD3, SRC, TERT, TNKS, TNKS2, TRPV1, XDH |
4.17287 |
|
[BP] GO:0016572 |
histone phosphorylation
|
AURKB, DRD1, PRKCA, PRKCB, PRKCD |
4.16381 |
|
[BP] GO:0050708 |
None
|
ACHE, CACNA1C, DRD2, DRD3, EGFR, GPER1, HCAR2, HIF1A, HTR2B, MIF, MMP12, PRKCA, PRKCE, SRC |
4.16381 |
|
[BP] GO:1900544 |
None
|
ADRB1, DRD1, DRD5, ESRRB, GPER1, HIF1A, HTR2A, INSR |
4.16381 |
|
[BP] GO:0045981 |
None
|
ADRB1, DRD1, DRD5, ESRRB, GPER1, HIF1A, HTR2A, INSR |
4.16381 |
|
[BP] GO:0050728 |
negative regulation of inflammatory response
|
ADORA1, CYP19A1, GBA, GPER1, PPARA, PRKCD, SMAD3, TEK |
4.16381 |
|
[BP] GO:0007198 |
None
|
HTR1A, HTR5A, HTR7 |
4.14857 |
|
[BP] GO:0032847 |
regulation of cellular pH reduction
|
BCL2, CA2, CA7 |
4.14857 |
|
[BP] GO:0008285 |
negative regulation of cell proliferation
|
ADORA1, ADORA3, ADRA1A, APP, AR, BCL2, CDK6, CYP1B1, DRD2, ERBB2, FABP3, GPER1, HSPA1A, IDO1, PTGS2, SMAD3, TERT, XDH |
4.11789 |
|
[BP] GO:0010676 |
None
|
ESRRB, GPER1, INSR, PPARA, PRKCE, SRC |
4.10035 |
|
[BP] GO:0006352 |
DNA-templated transcription, initiation
|
AR, ESR1, ESR2, ESRRA, ESRRB, NR3C1, NR3C2, PGR, PPARA, RORC |
4.10035 |
|
[BP] GO:0032230 |
positive regulation of synaptic transmission, GABAergic
|
ADRA1A, CA2, CA7, PRKCE |
4.10035 |
|
[BP] GO:2000106 |
regulation of leukocyte apoptotic process
|
AURKB, AXL, HCAR2, HIF1A, IDO1, MIF, PIK3CB |
4.09477 |
|
[BP] GO:0019752 |
carboxylic acid metabolic process
|
ALOX5, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, CYP2D6, DAO, FABP3, GBA2, GLO1, HIF1A, IDO1, MIF, PIM1, PPARA, PTGS1, PTGS2, TBXAS1, TYR |
4.09308 |
|
[BP] GO:0035265 |
organ growth
|
ADRA1A, AR, BCL2, CYP19A1, ESR1 |
4.02479 |
|
[BP] GO:0071900 |
regulation of protein serine/threonine kinase activity
|
ADORA1, DUSP3, EGFR, ERBB2, FLT3, GBA, HTR2A, HTR2B, IGF1R, INSR, MIF, PIK3CB, PRKCD, PTPN1, SRC |
4.02213 |
|
[BP] GO:0007186 |
G-protein coupled receptor signaling pathway
|
ADORA1, ADORA3, ADRA1A, ADRB1, APP, CA2, DRD1, DRD2, DRD3, DRD5, ESR1, GPER1, GPR35, HCAR2, HTR1A, HTR2A, HTR2B, HTR5A, HTR6, HTR7, INSR, PIK3CA, PIK3CB, SIGMAR1, SRC |
4.01995 |
|
[BP] GO:0033555 |
multicellular organismal response to stress
|
ADRB1, BCL2, DRD1, HTR1A, IDO1, PRKCG |
4.01206 |
|
[BP] GO:0018210 |
peptidyl-threonine modification
|
BCL2, CSNK2A1, DYRK1A, PRKCA, PRKCB, PRKCD, TNKS |
3.9966 |
|
[BP] GO:2001234 |
negative regulation of apoptotic signaling pathway
|
AR, BCL2, HIF1A, HSPA1A, MIF, MMP9, PTGS2, PTPN1, SRC, TERT |
3.9966 |
|
[BP] GO:0010564 |
regulation of cell cycle process
|
APEX1, APP, AURKB, BCL2, CDC25B, CDK6, CSNK2A1, CYP1A1, DRD2, DRD3, EGFR, GPER1, HSPA1A, INSR, MIF, PRKCE, TERT, TNKS |
3.99576 |
|
[BP] GO:0010557 |
positive regulation of macromolecule biosynthetic process
|
APP, AR, AURKB, DRD2, DRD3, EGFR, ERBB2, ESR1, ESR2, ESRRA, ESRRB, GBA, GPER1, HIF1A, IGF1R, INSR, KDR, MET, MMP12, NR3C1, PGR, PPARA, RORC, SMAD3, SRC, TERT, TNKS, TNKS2, TOP2A |
3.99576 |
|
[BP] GO:0010038 |
response to metal ion
|
APP, BCL2, CA2, CYP1A1, CYP1A2, DRD2, EGFR, FABP4, HIF1A, MMP9, PTGS2, TERT |
3.98768 |
|
[BP] GO:0043406 |
positive regulation of MAP kinase activity
|
ADORA1, EGFR, ERBB2, FLT3, HTR2A, HTR2B, INSR, MIF, PIK3CB, PTPN1, SRC |
3.97782 |
|
[BP] GO:0051054 |
positive regulation of DNA metabolic process
|
AURKB, DNMT1, EGFR, IGF1R, INSR, PRKCD, PRKCG, SRC, TNKS, TNKS2 |
3.96579 |
|
[BP] GO:0080135 |
regulation of cellular response to stress
|
APP, CDK6, DUSP3, DYRK1A, EGFR, HIF1A, HSPA1A, IGF1R, MET, MIF, NUAK1, PRKCD, PRKCG, PTGS2, PTPN1, TERT, XDH |
3.96579 |
|
[BP] GO:2001233 |
regulation of apoptotic signaling pathway
|
AR, BCL2, GPER1, HIF1A, HSPA1A, MIF, MMP9, PRKCD, PTGS2, PTPN1, SMAD3, SRC, TERT |
3.95892 |
|
[BP] GO:0007200 |
None
|
ADRA1A, DRD1, DRD2, DRD5, ESR1, HTR2A, HTR2B |
3.93714 |
|
[BP] GO:0040008 |
regulation of growth
|
ADRB1, APP, AR, BCL2, CSNK2A1, DRD2, DRD3, EGFR, ERBB2, ESR2, HIF1A, HSPA1A, INSR, PIK3CA, PIM1, SMAD3, TNKS2 |
3.93313 |
|
[BP] GO:0045860 |
positive regulation of protein kinase activity
|
ADORA1, CDC25B, DRD2, EGFR, ERBB2, FLT3, HTR2A, HTR2B, INSR, MIF, PIK3CA, PIK3CB, PRKCD, PTPN1, SRC |
3.92214 |
|
[BP] GO:0006082 |
organic acid metabolic process
|
ABCG2, ALOX5, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, CYP2D6, DAO, FABP3, GBA2, GLO1, HIF1A, IDO1, MIF, PIM1, PPARA, PTGS1, PTGS2, TBXAS1, TYR |
3.91643 |
|
[BP] GO:0050727 |
regulation of inflammatory response
|
ADORA1, CYP19A1, EGFR, ESR1, FABP4, GBA, GPER1, IDO1, PPARA, PRKCD, PTGS2, SMAD3, TEK |
3.87847 |
|
[BP] GO:0001963 |
None
|
DRD1, DRD2, DRD3, DRD5 |
3.84975 |
|
[BP] GO:0051937 |
None
|
DRD1, SLC22A1, SLC22A2, SLC22A3 |
3.84975 |
|
[BP] GO:2000379 |
positive regulation of reactive oxygen species metabolic process
|
EGFR, INSR, PRKCD, PTGS2, SMAD3, TRPV1, XDH |
3.84645 |
|
[BP] GO:0010605 |
negative regulation of macromolecule metabolic process
|
APEX1, APP, AR, AURKB, CSNK2A1, DNMT1, DRD3, DUSP3, DYRK1A, EGFR, ESR1, ESR2, ESRRA, FABP4, GBA, GPER1, HIF1A, HSPA1A, IGF1R, KDR, MIF, MMP12, MMP9, NR3C1, PGR, PPARA, PRKCD, PRKCE, PRKCG, PTGS2, PTPN1, RORC, SMAD3, SRC, TERT, TNKS, TNKS2, TRPV1, XDH |
3.84556 |
|
[BP] GO:1901342 |
regulation of vasculature development
|
CYP1B1, ERBB2, F3, GPER1, HIF1A, KDR, PRKCA, PRKCB, PTGS2, TEK, TERT, XDH |
3.83815 |
|
[BP] GO:0010863 |
positive regulation of phospholipase C activity
|
ADRA1A, EGFR, ESR1, HTR2A, HTR2B |
3.83687 |
|
[BP] GO:0051966 |
regulation of synaptic transmission, glutamatergic
|
ADORA1, DRD1, DRD2, EGFR, HTR2A, PTGS2 |
3.80717 |
|
[BP] GO:0030155 |
regulation of cell adhesion
|
BCL2, CDK6, CYP1B1, DUSP3, ERBB2, IDO1, KDR, NUAK1, PIK3CA, PIK3CB, PPARA, PRKCA, PRKCD, PRKCE, SMAD3, SRC, TEK |
3.80717 |
|
[BP] GO:0006109 |
regulation of carbohydrate metabolic process
|
ESRRB, GPER1, HIF1A, HTR2A, INSR, PPARA, PRKCE, RORC, SRC |
3.80717 |
|
[BP] GO:0000302 |
response to reactive oxygen species
|
AKR1B1, APEX1, AXL, BCL2, CYP1B1, EGFR, MMP9, PRKCD, SRC |
3.80717 |
|
[BP] GO:0043434 |
None
|
APEX1, FABP3, GPER1, HSD11B2, INSR, PPARA, PRKCD, PTGS2, SRC, TEK, TRPV1 |
3.78384 |
|
[BP] GO:0007167 |
enzyme linked receptor protein signaling pathway
|
AXL, EGFR, ERBB2, FLT3, IGF1R, INSR, KDR, MET, MMP2, MMP9, PIK3CA, PIK3CB, PRKCA, PTPN1, SMAD3, SRC, TEK |
3.76822 |
|
[BP] GO:0051246 |
regulation of protein metabolic process
|
ADORA1, ADRA1A, APP, AR, BCL2, CDC25B, CSNK2A1, DNMT1, DRD1, DRD2, DUSP3, DYRK1A, EGFR, ERBB2, ESR1, F3, FABP4, FLT3, GBA, GPER1, HSPA1A, HTR2A, HTR2B, IGF1R, INSR, KDR, MIF, MMP9, NUAK1, PIK3CA, PIK3CB, PRKCA, PRKCD, PRKCE, PRKCG, PTGS2, PTPN1, SMAD3, SRC, TEK, XDH |
3.76079 |
|
[BP] GO:0032225 |
None
|
DRD1, DRD2, DRD3, PTGS2 |
3.742 |
|
[BP] GO:1901654 |
None
|
AKR1B1, AR, CA9, CSNK2A1, EGFR, GBA, NR3C1, PRKCE, SRC |
3.73454 |
|
[BP] GO:0042446 |
hormone biosynthetic process
|
AKR1B1, CYP19A1, HSD11B1, HSD11B2, HSD17B1, HSD17B2 |
3.73438 |
|
[BP] GO:0048015 |
phosphatidylinositol-mediated signaling
|
ERBB2, HTR2A, HTR2B, IGF1R, PIK3CA, PIK3CB |
3.73438 |
|
[BP] GO:0021885 |
forebrain cell migration
|
AXL, DRD1, DRD2, EGFR, HTR6 |
3.72136 |
|
[BP] GO:0016477 |
cell migration
|
AXL, CYP1B1, DRD1, DRD2, EGFR, FUT7, HIF1A, HTR2B, HTR6, KDR, MIF, MMP1, MMP12, MMP9, PIK3CA, PIK3CB, PRKCD, SRC, TEK |
3.71718 |
|
[BP] GO:0051098 |
regulation of binding
|
APP, AURKB, BCL2, CYP2D6, MET, MMP9, PPARA, PRKCD, SMAD3, SRC, TERT, TNKS |
3.69924 |
|
[BP] GO:0050730 |
None
|
ADORA1, APP, EGFR, FLT3, HTR2A, MIF, PRKCD, PRKCE, PTPN1, SRC |
3.68643 |
|
[BP] GO:0007612 |
None
|
APP, DRD1, DRD2, DRD3, DRD5, HIF1A, INSR, PTGS2 |
3.67908 |
|
[BP] GO:0022414 |
reproductive process
|
AKR1B1, ALPL, APP, AR, AXL, BCL2, CDC25B, CYP19A1, CYP1A1, DRD1, DRD5, EGFR, ESR1, ESRRB, HIF1A, HSD11B2, HSD17B2, IDO1, INSR, MMP2, MMP9, PGR, PTGS2, SRC, TOP2A |
3.67093 |
|
[BP] GO:1900274 |
regulation of phospholipase C activity
|
ADRA1A, EGFR, ESR1, HTR2A, HTR2B |
3.66799 |
|
[BP] GO:0030817 |
None
|
ADRB1, DRD1, DRD2, DRD3, DRD5, GPER1, PRKCA |
3.62864 |
|
[BP] GO:0042752 |
None
|
ADORA1, DRD2, DRD3, PPARA, PRKCG, RORC, TOP2A |
3.62864 |
|
[BP] GO:0050795 |
None
|
ADORA1, DRD2, DRD3, HTR1A, HTR2A, HTR2B |
3.62545 |
|
[BP] GO:0048017 |
inositol lipid-mediated signaling
|
ERBB2, HTR2A, HTR2B, IGF1R, PIK3CA, PIK3CB |
3.62545 |
|
[BP] GO:0051384 |
response to glucocorticoid
|
ALPL, BCL2, EGFR, FLT3, GBA, HSD11B2, NR3C1, PTGS2 |
3.61571 |
|
[BP] GO:0007190 |
None
|
ADORA3, ADRB1, DRD1, DRD5, PRKCA |
3.61432 |
|
[BP] GO:0032467 |
None
|
AURKB, CDC25B, DRD2, DRD3, PRKCE |
3.61432 |
|
[BP] GO:1903532 |
None
|
ACHE, CYP19A1, DRD2, EGFR, GPER1, HCAR2, HIF1A, HTR2B, MIF, MMP12, PRKCE, SRC |
3.5497 |
|
[BP] GO:0045821 |
None
|
ESRRB, HIF1A, HTR2A, INSR |
3.54534 |
|
[BP] GO:0031329 |
regulation of cellular catabolic process
|
APEX1, BCL2, ESRRB, GBA, HIF1A, HSPA1A, HTR2A, HTR2B, INSR, KDR, MET, PIK3CA, PIK3CB, PPARA, PRKCA, PRKCD, PRKCG, PTPN1 |
3.52934 |
|
[BP] GO:0043436 |
oxoacid metabolic process
|
ALOX5, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, CYP2D6, DAO, FABP3, GBA2, GLO1, HIF1A, IDO1, MIF, PIM1, PPARA, PTGS1, PTGS2, TBXAS1, TYR |
3.50813 |
|
[BP] GO:0038128 |
None
|
EGFR, ERBB2, PIK3CA, PRKCA, SRC |
3.50608 |
|
[BP] GO:0001952 |
regulation of cell-matrix adhesion
|
BCL2, CDK6, KDR, PIK3CB, SMAD3, SRC, TEK |
3.4987 |
|
[BP] GO:0065007 |
biological regulation
|
ABCB1, ABCG2, ACHE, ADORA1, ADORA3, ADRA1A, ADRB1, AKR1B1, APEX1, APP, AR, AURKB, AXL, BACE1, BCL2, CA1, CA12, CA2, CA7, CA9, CACNA1C, CDC25B, CDK6, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2D6, DNMT1, DRD1, DRD2, DRD3, DRD5, DUSP3, DYRK1A, EGFR, ERBB2, ESR1, ESR2, ESRRA, ESRRB, F3, FABP3, FABP4, FLT3, GAA, GBA, GLO1, GPER1, GPR35, HCAR2, HIF1A, HSD11B1, HSD11B2, HSD17B1, HSD17B2, HSPA1A, HTR1A, HTR2A, HTR2B, HTR5A, HTR6, HTR7, IDO1, IGF1R, INSR, KDR, MET, MIF, MMP1, MMP12, MMP2, MMP9, NR3C1, NR3C2, NUAK1, PGR, PIK3CA, PIK3CB, PIM1, POLA1, POLB, PPARA, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, PTGS1, PTGS2, PTPN1, RORC, SIGMAR1, SLC22A1, SLC22A2, SLC22A3, SMAD3, SRC, TEK, TERT, TNKS, TNKS2, TOP2A, TRPV1, XDH |
3.46568 |
|
[BP] GO:0034599 |
cellular response to oxidative stress
|
AKR1B1, APEX1, AXL, CYP1B1, EGFR, HSPA1A, MMP9, PRKCD, SRC |
3.46032 |
|
[BP] GO:0051197 |
None
|
ESRRB, HIF1A, HTR2A, INSR |
3.45378 |
|
[BP] GO:0044236 |
multicellular organism metabolic process
|
ADRB1, HIF1A, MMP1, MMP12, MMP2, MMP9, TRPV1 |
3.42 |
|
[BP] GO:1904407 |
positive regulation of nitric oxide metabolic process
|
EGFR, INSR, PTGS2, SMAD3, TRPV1 |
3.40408 |
|
[BP] GO:0045429 |
positive regulation of nitric oxide biosynthetic process
|
EGFR, INSR, PTGS2, SMAD3, TRPV1 |
3.40408 |
|
[BP] GO:0060341 |
regulation of cellular localization
|
APP, AR, BCL2, CACNA1C, CSNK2A1, DRD1, DRD2, DRD3, EGFR, ERBB2, GPER1, HIF1A, PRKCD, PRKCE, PTGS2, PTPN1, SMAD3, SRC, TERT |
3.4013 |
|
[BP] GO:0007166 |
cell surface receptor signaling pathway
|
ADORA1, ADORA3, APP, AXL, BCL2, CA1, CSNK2A1, DRD2, EGFR, ERBB2, F3, FLT3, GPR35, IGF1R, INSR, KDR, MET, MIF, MMP2, MMP9, PIK3CA, PIK3CB, PRKCA, PRKCB, PRKCD, PRKCE, PTPN1, SMAD3, SRC, TEK, TNKS, TNKS2, TRPV1 |
3.39148 |
|
[BP] GO:0008306 |
None
|
APP, DRD1, DRD2, DRD3, DRD5, HIF1A |
3.38272 |
|
[BP] GO:0042542 |
response to hydrogen peroxide
|
AKR1B1, APEX1, AXL, BCL2, CYP1B1, PRKCD, SRC |
3.37405 |
|
[BP] GO:0034754 |
cellular hormone metabolic process
|
AKR1B1, CYP19A1, CYP1A1, CYP1B1, ESR1, HSD17B1, HSD17B2 |
3.37405 |
|
[BP] GO:0048148 |
None
|
DRD1, DRD2, DRD3, HTR2A |
3.36874 |
|
[BP] GO:0051234 |
None
|
ABCB1, ABCG2, ACHE, ADORA1, ADRA1A, ALOX5, APP, AR, AXL, CA1, CA12, CA14, CA2, CA3, CA4, CA5A, CA5B, CA6, CA7, CA9, CACNA1C, DRD1, DRD2, DRD3, EGFR, FABP3, FUCA1, GAA, HIF1A, HSPA1A, HTR2A, HTR2B, MGAM, MIF, MMP12, MMP9, PPARA, PRKCB, PRKCD, PRKCE, SIGMAR1, SLC22A1, SLC22A2, SLC22A3, SLC47A1, SLC47A2, SRC, TERT, TNKS, TRPV1, XDH |
3.36765 |
|
[BP] GO:0048869 |
cellular developmental process
|
ACHE, ADRB1, ALPL, APP, AR, AXL, BCL2, CDC25B, CDK6, CYP1A1, DRD1, DRD2, EGFR, ERBB2, ESR1, ESRRB, FABP4, FLT3, FUT7, GBA2, GLO1, HIF1A, HTR2B, KDR, MET, MIF, MMP2, MMP9, PGR, PRKCD, PTGS2, RORC, SMAD3, SRC, TEK, TERT, TOP2A |
3.33079 |
|
[BP] GO:0006584 |
None
|
AKR1B1, DAO, DRD1, DRD2, DRD3 |
3.31051 |
|
[BP] GO:0009712 |
None
|
AKR1B1, DAO, DRD1, DRD2, DRD3 |
3.31051 |
|
[BP] GO:0019219 |
regulation of nucleobase-containing compound metabolic process
|
ADORA3, ADRB1, APEX1, APP, AR, AURKB, CA9, CSNK2A1, CYP1B1, DNMT1, DRD1, DRD2, DRD3, DRD5, DYRK1A, EGFR, ERBB2, ESR1, ESR2, ESRRA, ESRRB, FABP4, GLO1, GPER1, HIF1A, HSPA1A, HTR2A, IGF1R, INSR, MET, MMP12, NR3C1, NR3C2, PGR, PIK3CA, PIM1, POLA1, PPARA, PRKCA, PRKCB, PRKCD, PRKCG, PTPN1, RORC, SMAD3, SRC, TERT, TNKS, TNKS2, TOP2A, TRPV1 |
3.30137 |
|
[BP] GO:0009896 |
positive regulation of catabolic process
|
CSNK2A1, ESRRB, GBA, HIF1A, HSPA1A, HTR2A, INSR, KDR, PIK3CB, PPARA, PRKCD, PRKCE, PTPN1 |
3.30137 |
|
[BP] GO:0051128 |
regulation of cellular component organization
|
APP, AR, AURKB, AXL, BCL2, CSNK2A1, DNMT1, DRD2, DRD3, EGFR, ERBB2, ESR1, ESR2, GBA, GPER1, HIF1A, HSPA1A, IGF1R, INSR, KDR, MET, MMP1, MMP9, PIK3CB, PRKCD, PRKCE, PRKCG, PTPN1, SMAD3, SRC, TEK, TNKS, TNKS2, TOP2A |
3.29787 |
|
[BP] GO:0071383 |
None
|
AR, EGFR, FLT3, GPER1, NR3C1, SRC |
3.28948 |
|
[BP] GO:0015844 |
None
|
DRD1, SLC22A1, SLC22A2, SLC22A3 |
3.28863 |
|
[BP] GO:0043393 |
regulation of protein binding
|
APP, AURKB, BCL2, MET, MMP9, PPARA, PRKCD, SRC, TERT |
3.28833 |
|
[BP] GO:0051701 |
interaction with host
|
AXL, EGFR, HSPA1A, HTR2A, INSR, MET, SMAD3, SRC |
3.24371 |
|
[BP] GO:2001242 |
regulation of intrinsic apoptotic signaling pathway
|
BCL2, HIF1A, HSPA1A, MIF, MMP9, PTGS2, PTPN1, SRC |
3.24371 |
|
[BP] GO:0009895 |
negative regulation of catabolic process
|
ADORA1, BCL2, EGFR, HCAR2, HTR2B, MET, PIK3CA, PPARA, PRKCG, SMAD3 |
3.2391 |
|
[BP] GO:0007193 |
None
|
ADORA1, DRD2, DRD3, HTR1A, HTR5A, HTR7 |
3.23127 |
|
[BP] GO:0048661 |
positive regulation of smooth muscle cell proliferation
|
AKR1B1, EGFR, MMP2, MMP9, PTGS2, TERT |
3.23127 |
|
[BP] GO:0051179 |
None
|
ABCB1, ABCG2, ACHE, ADORA1, ADRA1A, ALOX5, APP, AR, AURKB, AXL, CA1, CA12, CA14, CA2, CA3, CA4, CA5A, CA5B, CA6, CA7, CA9, CACNA1C, DRD1, DRD2, DRD3, EGFR, ESR1, FABP3, FUCA1, GAA, HIF1A, HSPA1A, HTR2A, HTR2B, MGAM, MIF, MMP12, MMP9, PPARA, PRKCB, PRKCD, PRKCE, SIGMAR1, SLC22A1, SLC22A2, SLC22A3, SLC47A1, SLC47A2, SRC, TERT, TNKS, TNKS2, TRPV1, XDH |
3.23127 |
|
[BP] GO:0003012 |
None
|
ADORA1, ADRA1A, DRD1, DRD2, GAA, HTR2A, HTR2B, HTR7, PIK3CA, TRPV1 |
3.22937 |
|
[BP] GO:0051209 |
None
|
DRD2, HTR2A, HTR2B, PRKCE, TRPV1 |
3.22825 |
|
[BP] GO:0051283 |
None
|
DRD2, HTR2A, HTR2B, PRKCE, TRPV1 |
3.22825 |
|
[BP] GO:0051094 |
positive regulation of developmental process
|
APP, AR, AXL, BCL2, CA2, CYP1B1, DRD2, ESRRB, F3, GPER1, HIF1A, HTR2A, IDO1, INSR, KDR, PIM1, PRKCA, PRKCB, PTGS2, SMAD3, SRC, TEK, TERT |
3.22788 |
|
[BP] GO:0051194 |
None
|
ESRRB, HIF1A, HTR2A, INSR |
3.21747 |
|
[BP] GO:0051052 |
regulation of DNA metabolic process
|
AURKB, DNMT1, EGFR, GPER1, IGF1R, INSR, PIK3CA, PRKCD, PRKCG, SRC, TNKS, TNKS2 |
3.21724 |
|
[BP] GO:0003006 |
developmental process involved in reproduction
|
ALPL, AR, AXL, BCL2, CDC25B, CYP19A1, EGFR, ESR1, ESRRB, HIF1A, HSD17B2, INSR, PGR, PTGS2, SRC |
3.20294 |
|
[BP] GO:0030814 |
None
|
ADRB1, DRD1, DRD2, DRD3, DRD5, GPER1, PRKCA |
3.19695 |
|
[BP] GO:0048870 |
cell motility
|
AXL, CYP1B1, DRD1, DRD2, EGFR, FUT7, HIF1A, HTR2B, HTR6, KDR, MIF, MMP1, MMP12, MMP9, PIK3CA, PIK3CB, PRKCD, SRC, TEK |
3.19584 |
|
[BP] GO:0022900 |
electron transport chain
|
AKR1B1, ALDH2, AOX1, CYP19A1, CYP1A2, IDO1, NQO2, XDH |
3.17826 |
|
[BP] GO:0006936 |
None
|
ADRA1A, DRD1, DRD2, GAA, HTR2A, HTR2B, HTR7, PIK3CA, TRPV1 |
3.15744 |
|
[BP] GO:0016042 |
lipid catabolic process
|
ADORA1, AKR1B10, CYP19A1, CYP1A2, CYP1B1, FABP3, FABP4, FUCA1, GBA, GBA2 |
3.15481 |
|
[BP] GO:0010632 |
regulation of epithelial cell migration
|
HIF1A, KDR, MET, MMP9, PRKCA, PRKCE, PTGS2, SRC, TEK |
3.14484 |
|
[BP] GO:2000107 |
negative regulation of leukocyte apoptotic process
|
AURKB, AXL, HIF1A, IDO1, MIF |
3.14484 |
|
[BP] GO:0038083 |
peptidyl-tyrosine autophosphorylation
|
EGFR, IGF1R, INSR, KDR, SRC |
3.14484 |
|
[BP] GO:0043065 |
positive regulation of apoptotic process
|
BCL2, CYP1B1, F3, GPER1, HCAR2, IDO1, MMP9, PIK3CB, PRKCD, PTGS2, SMAD3, SRC, TOP2A, TRPV1, XDH |
3.14349 |
|
[BP] GO:0051940 |
None
|
DRD1, DRD2, DRD3 |
3.1369 |
|
[BP] GO:0016139 |
None
|
FUCA1, GBA, GBA2 |
3.1369 |
|
[BP] GO:0051584 |
None
|
DRD1, DRD2, DRD3 |
3.1369 |
|
[BP] GO:0030802 |
None
|
ADRB1, DRD1, DRD2, DRD3, DRD5, GPER1, PRKCA |
3.13516 |
|
[BP] GO:0051241 |
negative regulation of multicellular organismal process
|
ADORA1, ADRA1A, ADRB1, APP, AXL, BCL2, CDK6, DRD2, DRD3, EGFR, ERBB2, GBA, GPR35, HIF1A, IDO1, PRKCD, PTGS2, SMAD3, TEK, TERT, XDH |
3.12713 |
|
[BP] GO:0097237 |
cellular response to toxic substance
|
AKR1B1, APEX1, AXL, CYP1B1, KDR, PRKCD, PRKCE |
3.11323 |
|
[BP] GO:0090068 |
positive regulation of cell cycle process
|
APEX1, APP, AURKB, CDC25B, CYP1A1, DRD2, DRD3, INSR, PRKCE, TERT |
3.10941 |
|
[BP] GO:0008542 |
None
|
APP, DRD1, DRD2, DRD3, HIF1A |
3.10728 |
|
[BP] GO:0042391 |
None
|
ADORA1, ADRA1A, APP, BCL2, CACNA1C, DRD1, GBA, GPER1, GPR35, KDR, SRC, TRPV1 |
3.10366 |
|
[BP] GO:0050878 |
regulation of body fluid levels
|
ADORA1, AKR1B1, DRD2, F3, GBA, HIF1A, MET, PRKCA, PRKCD, PRKCE, SLC22A2, XDH |
3.10366 |
|
[BP] GO:0043068 |
positive regulation of programmed cell death
|
BCL2, CYP1B1, F3, GPER1, HCAR2, IDO1, MMP9, PIK3CB, PRKCD, PTGS2, SMAD3, SRC, TOP2A, TRPV1, XDH |
3.10325 |
|
[BP] GO:1901655 |
None
|
AKR1B1, AR, EGFR, NR3C1, PRKCE, SRC |
3.09763 |
|
[BP] GO:0010675 |
None
|
ESRRB, GPER1, INSR, PPARA, PRKCE, RORC, SRC |
3.09582 |
|
[BP] GO:0008210 |
estrogen metabolic process
|
CYP19A1, CYP1B1, HSD17B1, HSD17B2 |
3.08318 |
|
[BP] GO:0007202 |
None
|
ADRA1A, EGFR, HTR2A, HTR2B |
3.08318 |
|
[BP] GO:0051254 |
None
|
APP, AR, DRD2, DRD3, EGFR, ERBB2, ESR1, ESR2, ESRRA, ESRRB, GPER1, HIF1A, HSPA1A, INSR, MET, MMP12, NR3C1, PGR, PPARA, RORC, SMAD3, SRC, TERT, TNKS, TOP2A |
3.08318 |
|
[BP] GO:0040011 |
locomotion
|
AXL, CYP1B1, DRD1, DRD2, EGFR, FUT7, HIF1A, HTR2B, HTR6, KDR, MET, MIF, MMP1, MMP12, MMP9, PIK3CA, PIK3CB, PRKCD, SRC, TEK |
3.08305 |
|
[BP] GO:0009889 |
regulation of biosynthetic process
|
ADORA3, ADRB1, APEX1, APP, AR, AURKB, BCL2, CA9, CSNK2A1, CYP1B1, DNMT1, DRD1, DRD2, DRD3, DRD5, EGFR, ERBB2, ESR1, ESR2, ESRRA, ESRRB, FABP3, FABP4, GBA, GLO1, GPER1, HIF1A, HSPA1A, HTR2A, HTR2B, IGF1R, INSR, KDR, MET, MMP12, NR3C1, NR3C2, PGR, PIM1, POLA1, PPARA, PRKCA, PRKCB, PRKCD, PTGS2, RORC, SMAD3, SRC, TERT, TNKS, TNKS2, TOP2A, TRPV1 |
3.07558 |
|
[BP] GO:0044070 |
regulation of anion transport
|
ABCB1, ADORA1, CA2, CA7, MIF, PRKCD |
3.07315 |
|
[BP] GO:0010518 |
positive regulation of phospholipase activity
|
ADRA1A, EGFR, ESR1, HTR2A, HTR2B |
3.07315 |
|
[BP] GO:0006810 |
None
|
ABCB1, ABCG2, ACHE, ADORA1, ADRA1A, ALOX5, APP, AR, AXL, CA1, CA12, CA14, CA2, CA3, CA4, CA5A, CA5B, CA6, CA7, CA9, CACNA1C, DRD1, DRD2, DRD3, FABP3, FUCA1, GAA, HIF1A, HSPA1A, HTR2A, HTR2B, MGAM, MIF, MMP12, MMP9, PPARA, PRKCB, PRKCD, PRKCE, SIGMAR1, SLC22A1, SLC22A2, SLC22A3, SLC47A1, SLC47A2, SRC, TNKS, TRPV1, XDH |
3.05819 |
|
[BP] GO:0032103 |
positive regulation of response to external stimulus
|
EGFR, F3, FABP4, IDO1, KDR, MET, MIF, PRKCA, PTGS2, SMAD3 |
3.05476 |
|
[BP] GO:0023052 |
None
|
ADORA1, ADRA1A, ADRB1, AR, CACNA1C, DRD1, DRD2, DRD3, DRD5, ESR2, HTR2A, HTR6, HTR7, PGR, PRKCG, TEK |
3.0528 |
|
[BP] GO:0001816 |
cytokine production
|
APP, FABP4, HIF1A, IDO1, PRKCD, PTGS2 |
3.04703 |
|
[BP] GO:0032355 |
response to estradiol
|
CYP1A2, EGFR, ESR1, ESRRA, GPER1, HTR5A, PTGS2 |
3.03694 |
|
[BP] GO:0032870 |
cellular response to hormone stimulus
|
APEX1, AR, EGFR, ESR1, FLT3, GPER1, INSR, NR3C1, PRKCD, PRKCE, SRC |
3.02698 |
|
[BP] GO:0051781 |
None
|
AURKB, CDC25B, DRD2, DRD3, HTR2B, PRKCE |
3.02083 |
|
[BP] GO:0002009 |
morphogenesis of an epithelium
|
AR, BCL2, CA2, CA9, EGFR, ESR1, HIF1A, MET, SMAD3, SRC |
3.02083 |
|
[BP] GO:0046887 |
positive regulation of hormone secretion
|
CYP19A1, DRD2, EGFR, GPER1, HCAR2, HIF1A, PRKCE |
3.01851 |
|
[BP] GO:0007267 |
None
|
ADORA1, ADRA1A, ADRB1, AR, DRD1, DRD2, DRD3, DRD5, ESR2, HTR2A, HTR6, HTR7, PGR, PRKCG, TEK |
3.01437 |
|
[BP] GO:0043412 |
macromolecule modification
|
ALPI, ALPL, APEX1, APP, AR, AURKB, AXL, BCL2, CDC25B, CDK6, CSNK2A1, DNMT1, DRD1, DUSP3, DYRK1A, EGFR, ERBB2, ESR1, FLT3, FUT7, HIF1A, HTR2B, IGF1R, INSR, KDR, MET, NR3C1, NUAK1, PIK3CA, PIM1, POLB, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, PTPN1, SMAD3, SRC, TEK, TNKS, TNKS2, TOP2A |
2.99579 |
|
[BP] GO:0010595 |
positive regulation of endothelial cell migration
|
HIF1A, KDR, MET, PRKCA, PTGS2, TEK |
2.99534 |
|
[BP] GO:0071073 |
None
|
FABP3, HTR2A, HTR2B |
2.99089 |
|
[BP] GO:0009416 |
response to light stimulus
|
APP, AURKB, BCL2, DRD1, DRD2, DRD3, EGFR, HIF1A, PTGS2, TYR |
2.98978 |
|
[BP] GO:1903522 |
None
|
ADORA1, ADORA3, ADRA1A, ADRB1, CACNA1C, DRD2, EGFR, GAA, HTR2A, PTGS2 |
2.98978 |
|
[BP] GO:0045893 |
None
|
APP, AR, DRD2, DRD3, EGFR, ERBB2, ESR1, ESR2, ESRRA, ESRRB, GPER1, HIF1A, INSR, MET, MMP12, NR3C1, PGR, PPARA, RORC, SMAD3, SRC, TERT, TNKS, TOP2A |
2.98199 |
|
[BP] GO:1903508 |
None
|
APP, AR, DRD2, DRD3, EGFR, ERBB2, ESR1, ESR2, ESRRA, ESRRB, GPER1, HIF1A, INSR, MET, MMP12, NR3C1, PGR, PPARA, RORC, SMAD3, SRC, TERT, TNKS, TOP2A |
2.98199 |
|
[BP] GO:1902680 |
None
|
APP, AR, DRD2, DRD3, EGFR, ERBB2, ESR1, ESR2, ESRRA, ESRRB, GPER1, HIF1A, INSR, MET, MMP12, NR3C1, PGR, PPARA, RORC, SMAD3, SRC, TERT, TNKS, TOP2A |
2.97782 |
|
[BP] GO:0001938 |
None
|
F3, HIF1A, HTR2B, KDR, PRKCA, TEK |
2.97449 |
|
[BP] GO:1903428 |
positive regulation of reactive oxygen species biosynthetic process
|
EGFR, INSR, PTGS2, SMAD3, TRPV1 |
2.96702 |
|
[BP] GO:0050994 |
None
|
ADORA1, HCAR2, PPARA, PRKCD, PRKCE |
2.96702 |
|
[BP] GO:0008150 |
biological_process
|
ABCB1, ABCG2, ACHE, ADORA1, ADORA3, ADRA1A, ADRB1, AKR1B1, AKR1B10, ALDH2, ALOX5, ALPI, ALPL, AOX1, APEX1, APP, AR, AURKB, AXL, BACE1, BCL2, CA1, CA12, CA14, CA2, CA3, CA4, CA5A, CA5B, CA6, CA7, CA9, CACNA1C, CDC25B, CDK6, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, CYP2D6, DAO, DNMT1, DRD1, DRD2, DRD3, DRD5, DUSP3, DYRK1A, EGFR, ERBB2, ESR1, ESR2, ESRRA, ESRRB, F3, FABP3, FABP4, FLT3, FUCA1, FUT7, GAA, GBA, GBA2, GLO1, GPER1, GPR35, HCAR2, HIF1A, HSD11B1, HSD11B2, HSD17B1, HSD17B2, HSPA1A, HTR1A, HTR2A, HTR2B, HTR5A, HTR6, HTR7, IDO1, IGF1R, INSR, KDR, MET, MGAM, MIF, MMP1, MMP12, MMP2, MMP9, NQO2, NR3C1, NR3C2, NUAK1, PGR, PIK3CA, PIK3CB, PIM1, POLA1, POLB, PPARA, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, PTGS1, PTGS2, PTPN1, RORC, SIGMAR1, SLC22A1, SLC22A2, SLC22A3, SLC47A1, SLC47A2, SMAD3, SRC, TBXAS1, TEK, TERT, TNKS, TNKS2, TOP2A, TRPV1, TYR, XDH |
2.96702 |
|
[BP] GO:0048660 |
regulation of smooth muscle cell proliferation
|
AKR1B1, EGFR, GPER1, MMP2, MMP9, PTGS2, TERT |
2.96702 |
|
[BP] GO:0046466 |
None
|
CYP1B1, FUCA1, GBA, GBA2 |
2.96702 |
|
[BP] GO:0001975 |
None
|
DRD1, DRD2, DRD3, DRD5 |
2.96702 |
|
[BP] GO:0071902 |
positive regulation of protein serine/threonine kinase activity
|
ADORA1, EGFR, ERBB2, FLT3, HTR2A, HTR2B, INSR, MIF, PIK3CB, PTPN1, SRC |
2.95468 |
|
[BP] GO:1900371 |
None
|
ADRB1, DRD1, DRD2, DRD3, DRD5, GPER1, PRKCA |
2.9472 |
|
[BP] GO:0031326 |
regulation of cellular biosynthetic process
|
ADORA3, ADRB1, APEX1, APP, AR, AURKB, BCL2, CA9, CSNK2A1, CYP1B1, DNMT1, DRD1, DRD2, DRD3, DRD5, EGFR, ERBB2, ESR1, ESR2, ESRRA, ESRRB, FABP3, FABP4, GBA, GLO1, GPER1, HIF1A, HSPA1A, HTR2A, HTR2B, IGF1R, INSR, MET, MMP12, NR3C1, NR3C2, PGR, PIM1, POLA1, PPARA, PRKCA, PRKCB, PRKCD, PTGS2, RORC, SMAD3, SRC, TERT, TNKS, TNKS2, TOP2A, TRPV1 |
2.93824 |
|
[BP] GO:0007632 |
None
|
APP, DRD1, DRD2, DRD3, HIF1A |
2.93288 |
|
[BP] GO:1900182 |
positive regulation of protein localization to nucleus
|
APP, EGFR, PRKCD, PTGS2, SMAD3, SRC, TERT |
2.92956 |
|
[BP] GO:0030808 |
None
|
ADRB1, DRD1, DRD2, DRD3, DRD5, GPER1, PRKCA |
2.92956 |
|
[BP] GO:0060359 |
None
|
DRD1, DRD2, DRD3, DRD5, PRKCE, PRKCG |
2.92877 |
|
[BP] GO:0044267 |
cellular protein metabolic process
|
ALPI, ALPL, APP, AR, AURKB, AXL, BACE1, BCL2, CDC25B, CDK6, CSNK2A1, DRD1, DUSP3, DYRK1A, EGFR, ERBB2, ESR1, FLT3, FUT7, HIF1A, HTR2B, IGF1R, INSR, KDR, MET, MMP1, MMP2, NUAK1, PIK3CA, PIM1, POLB, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, PTPN1, SMAD3, SRC, TEK, TNKS, TNKS2, TOP2A |
2.92726 |
|
[BP] GO:0010959 |
None
|
ADORA1, BCL2, CACNA1C, DRD1, DRD2, DRD3, GPER1, GPR35, HTR2A, PRKCE, PTGS2 |
2.91682 |
|
[BP] GO:0071396 |
cellular response to lipid
|
AR, AXL, CDK6, EGFR, ESR1, FLT3, GPER1, NR3C1, PRKCE, RORC, SRC |
2.90723 |
|
[BP] GO:0045934 |
None
|
APEX1, AR, AURKB, DNMT1, DRD2, DRD3, DYRK1A, ESR1, ESR2, ESRRA, FABP4, GPER1, HSPA1A, MMP12, NR3C1, PPARA, PRKCA, RORC, SMAD3, SRC, TERT, TNKS, TNKS2, TRPV1 |
2.9058 |
|
[BP] GO:0001936 |
None
|
F3, HIF1A, HTR2B, KDR, PRKCA, TEK, XDH |
2.87291 |
|
[BP] GO:0007191 |
None
|
DRD1, DRD3, DRD5 |
2.86361 |
|
[BP] GO:2001225 |
regulation of chloride transport
|
ABCB1, CA2, CA7 |
2.86361 |
|
[BP] GO:0097267 |
omega-hydroxylase P450 pathway
|
CYP1A1, CYP1A2, CYP1B1 |
2.86361 |
|
[BP] GO:0045765 |
regulation of angiogenesis
|
CYP1B1, ERBB2, F3, HIF1A, KDR, PRKCA, PRKCB, PTGS2, TEK, TERT |
2.86133 |
|
[BP] GO:0010628 |
positive regulation of gene expression
|
APP, AR, DNMT1, DRD1, DRD2, DRD3, EGFR, ERBB2, ESR1, ESR2, ESRRA, ESRRB, GPER1, HIF1A, HSPA1A, INSR, MET, MMP12, NR3C1, PGR, PIK3CB, PPARA, RORC, SMAD3, SRC, TERT, TNKS, TOP2A |
2.85965 |
|
[BP] GO:0043279 |
None
|
DRD2, DRD3, DRD5, PRKCE, PRKCG, TRPV1 |
2.85697 |
|
[BP] GO:0033032 |
regulation of myeloid cell apoptotic process
|
BCL2, HCAR2, MIF, PIK3CB |
2.85379 |
|
[BP] GO:0042417 |
None
|
DAO, DRD1, DRD2, DRD3 |
2.85379 |
|
[BP] GO:0006464 |
cellular protein modification process
|
ALPI, ALPL, APP, AR, AURKB, AXL, BCL2, CDC25B, CDK6, CSNK2A1, DRD1, DUSP3, DYRK1A, EGFR, ERBB2, ESR1, FLT3, FUT7, HIF1A, HTR2B, IGF1R, INSR, KDR, MET, NUAK1, PIK3CA, PIM1, POLB, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, PTPN1, SMAD3, SRC, TEK, TNKS, TNKS2, TOP2A |
2.85347 |
|
[BP] GO:0036211 |
protein modification process
|
ALPI, ALPL, APP, AR, AURKB, AXL, BCL2, CDC25B, CDK6, CSNK2A1, DRD1, DUSP3, DYRK1A, EGFR, ERBB2, ESR1, FLT3, FUT7, HIF1A, HTR2B, IGF1R, INSR, KDR, MET, NUAK1, PIK3CA, PIM1, POLB, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, PTPN1, SMAD3, SRC, TEK, TNKS, TNKS2, TOP2A |
2.85347 |
|
[BP] GO:0007623 |
circadian rhythm
|
DRD2, DRD3, DYRK1A, EGFR, HTR7, PPARA, RORC |
2.81929 |
|
[BP] GO:1901215 |
negative regulation of neuron death
|
AXL, BCL2, GBA, HIF1A, PIK3CA, PPARA, PRKCG, TERT |
2.81616 |
|
[BP] GO:0048732 |
gland development
|
AR, BCL2, CSNK2A1, CYP19A1, EGFR, INSR, PIK3CA, SMAD3, TYR |
2.80684 |
|
[BP] GO:0032409 |
None
|
ABCB1, APP, BCL2, DRD2, DRD3, GPR35, MMP9, PRKCD, PRKCE |
2.80684 |
|
[BP] GO:0006807 |
nitrogen compound metabolic process
|
ABCG2, ACHE, AKR1B1, AKR1B10, ALPI, ALPL, AOX1, APEX1, APP, AR, AURKB, AXL, BACE1, BCL2, CDC25B, CDK6, CSNK2A1, CYP1A1, CYP1A2, CYP1B1, CYP2D6, DAO, DNMT1, DRD1, DRD2, DRD3, DUSP3, DYRK1A, EGFR, ERBB2, ESR1, ESR2, ESRRA, ESRRB, F3, FLT3, FUCA1, FUT7, GBA, GBA2, GLO1, HIF1A, HSPA1A, HTR1A, HTR2B, IDO1, IGF1R, INSR, KDR, MET, MMP1, MMP12, MMP2, MMP9, NR3C1, NR3C2, NUAK1, PGR, PIK3CA, PIM1, POLA1, POLB, PPARA, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, PTGS2, PTPN1, RORC, SMAD3, SRC, TEK, TERT, TNKS, TNKS2, TOP2A, TYR, XDH |
2.8022 |
|
[BP] GO:0097553 |
None
|
DRD2, HTR2A, HTR2B, PRKCE, TRPV1 |
2.8022 |
|
[BP] GO:0072347 |
None
|
DRD2, DRD3, DRD5, PRKCE, PRKCG |
2.8022 |
|
[BP] GO:0045428 |
regulation of nitric oxide biosynthetic process
|
EGFR, INSR, PTGS2, SMAD3, TRPV1 |
2.8022 |
|
[BP] GO:0070229 |
negative regulation of lymphocyte apoptotic process
|
AURKB, HIF1A, IDO1, MIF |
2.8022 |
|
[BP] GO:0010810 |
regulation of cell-substrate adhesion
|
BCL2, CDK6, KDR, PIK3CB, PRKCE, SMAD3, SRC, TEK |
2.79071 |
|
[BP] GO:0010942 |
positive regulation of cell death
|
BCL2, CYP1B1, F3, GPER1, HCAR2, IDO1, MMP9, PIK3CB, PRKCD, PTGS2, SMAD3, SRC, TOP2A, TRPV1, XDH |
2.78912 |
|
[BP] GO:0034762 |
None
|
ABCB1, APP, BCL2, CA2, CACNA1C, DRD1, DRD2, DRD3, GPER1, GPR35, MMP9, PRKCE |
2.77861 |
|
[BP] GO:0071363 |
cellular response to growth factor stimulus
|
APP, EGFR, ERBB2, INSR, KDR, NR3C1, SMAD3, SRC, TRPV1 |
2.77861 |
|
[BP] GO:0001997 |
None
|
ADRA1A, ADRB1 |
2.77861 |
|
[BP] GO:0046960 |
None
|
DRD1, DRD5 |
2.77861 |
|
[BP] GO:0035408 |
None
|
PRKCA, PRKCB |
2.77861 |
|
[BP] GO:0006680 |
None
|
GBA, GBA2 |
2.77861 |
|
[BP] GO:0009115 |
None
|
AOX1, XDH |
2.77861 |
|
[BP] GO:0006286 |
base-excision repair, base-free sugar-phosphate removal
|
APEX1, POLB |
2.77861 |
|
[BP] GO:0002031 |
None
|
DRD2, DRD3, HTR2B |
2.75661 |
|
[BP] GO:0060736 |
prostate gland growth
|
AR, CYP19A1, ESR1 |
2.75661 |
|
[BP] GO:0019371 |
None
|
PTGS1, PTGS2, TBXAS1 |
2.75661 |
|
[BP] GO:0003014 |
None
|
ADORA1, ADRA1A, AKR1B1, BCL2, DRD2, HSD11B2 |
2.75326 |
|
[BP] GO:0034502 |
protein localization to chromosome
|
AURKB, ESR1, TERT, TNKS, TNKS2 |
2.74757 |
|
[BP] GO:0010517 |
regulation of phospholipase activity
|
ADRA1A, EGFR, ESR1, HTR2A, HTR2B |
2.74757 |
|
[BP] GO:0051336 |
regulation of hydrolase activity
|
ADRA1A, ADRB1, APP, CSNK2A1, DRD2, EGFR, ERBB2, ESR1, F3, GPER1, HSPA1A, HTR2A, HTR2B, MMP9, NUAK1, PRKCD, PTGS2, PTPN1, SMAD3, SRC, XDH |
2.73362 |
|
[BP] GO:0030799 |
None
|
ADRB1, DRD1, DRD2, DRD3, DRD5, GPER1, PRKCA |
2.72631 |
|
[BP] GO:0048638 |
regulation of developmental growth
|
ADRB1, APP, AR, BCL2, DRD2, DRD3, INSR, PIK3CA, PIM1, TNKS2 |
2.72561 |
|
[BP] GO:0051302 |
None
|
AURKB, CDC25B, DRD2, DRD3, ESRRB, HTR2B, PRKCE |
2.70908 |
|
[BP] GO:0006928 |
movement of cell or subcellular component
|
APP, AXL, CYP1B1, DRD1, DRD2, EGFR, ERBB2, FUT7, HIF1A, HTR2B, HTR6, KDR, MIF, MMP1, MMP12, MMP9, PIK3CA, PIK3CB, PRKCA, PRKCD, PTGS2, SRC, TEK |
2.70732 |
|
[BP] GO:0010039 |
response to iron ion
|
BCL2, CYP1A1, DRD2, HIF1A |
2.70648 |
|
[BP] GO:0006357 |
None
|
APP, AR, AURKB, CA9, DNMT1, DRD2, DRD3, EGFR, ERBB2, ESR1, ESR2, ESRRA, ESRRB, GLO1, GPER1, HIF1A, HSPA1A, MET, MMP12, NR3C1, PGR, PPARA, PRKCB, RORC, SMAD3, TERT, TNKS, TOP2A, TRPV1 |
2.69852 |
|
[BP] GO:0045321 |
leukocyte activation
|
ALOX5, AXL, BCL2, FLT3, FUCA1, FUT7, GAA, HSPA1A, MGAM, MIF, MMP9, PRKCB, PRKCD, PRKCE, RORC, SMAD3, TRPV1 |
2.69748 |
|
[BP] GO:0033138 |
positive regulation of peptidyl-serine phosphorylation
|
APP, BCL2, EGFR, MIF, PIK3CA, PTGS2 |
2.68742 |
|
[BP] GO:1901184 |
None
|
ADORA1, APP, EGFR, ERBB2, GPER1, MMP9 |
2.68742 |
|
[BP] GO:0070301 |
cellular response to hydrogen peroxide
|
AKR1B1, APEX1, AXL, CYP1B1, PRKCD |
2.68699 |
|
[BP] GO:1901575 |
None
|
ACHE, ADORA1, AKR1B10, ALDH2, AOX1, AURKB, BACE1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A6, CYP2D6, DAO, FABP3, FABP4, FUCA1, FUT7, GAA, GBA, GBA2, HSPA1A, IDO1, MGAM, XDH |
2.68699 |
|
[BP] GO:0022029 |
None
|
DRD1, DRD2, EGFR, HTR6 |
2.65922 |
|
[BP] GO:0043278 |
None
|
DRD2, DRD3, PRKCE, PRKCG |
2.65922 |
|
[BP] GO:0014072 |
None
|
DRD2, DRD3, PRKCE, PRKCG |
2.65922 |
|
[BP] GO:0042596 |
None
|
ADRB1, BCL2, DRD1, HTR1A |
2.65922 |
|
[BP] GO:0060193 |
positive regulation of lipase activity
|
ADRA1A, EGFR, ESR1, HTR2A, HTR2B |
2.65733 |
|
[BP] GO:0001525 |
angiogenesis
|
CYP1B1, HIF1A, KDR, MMP2, PIK3CA, PIK3CB, PRKCA, PTGS2, TEK |
2.6549 |
|
[BP] GO:0015697 |
None
|
SLC22A1, SLC22A2, SLC22A3 |
2.65222 |
|
[BP] GO:0051828 |
entry into other organism involved in symbiotic interaction
|
AXL, EGFR, HSPA1A, HTR2A, MET, SRC |
2.6499 |
|
[BP] GO:0030260 |
entry into host cell
|
AXL, EGFR, HSPA1A, HTR2A, MET, SRC |
2.6499 |
|
[BP] GO:0051806 |
entry into cell of other organism involved in symbiotic interaction
|
AXL, EGFR, HSPA1A, HTR2A, MET, SRC |
2.6499 |
|
[BP] GO:0044409 |
entry into host
|
AXL, EGFR, HSPA1A, HTR2A, MET, SRC |
2.6499 |
|
[BP] GO:1903827 |
regulation of cellular protein localization
|
APP, AR, BCL2, CSNK2A1, EGFR, ERBB2, GPER1, PRKCD, PRKCE, PTGS2, PTPN1, SMAD3, SRC, TERT |
2.63948 |
|
[BP] GO:0072593 |
reactive oxygen species metabolic process
|
BCL2, CYP1A1, CYP1A2, CYP1B1, DRD5, EGFR |
2.6294 |
|
[BP] GO:0001101 |
response to acid chemical
|
AKR1B1, DNMT1, EGFR, FABP3, HSD17B2, KDR, MMP2, PRKCE, PTGS2, SRC |
2.62132 |
|
[BP] GO:1902893 |
None
|
HIF1A, PPARA, SMAD3, TERT |
2.61843 |
|
[BP] GO:0010907 |
None
|
ESRRB, INSR, PPARA, SRC |
2.61843 |
|
[BP] GO:0045907 |
None
|
ADRA1A, EGFR, HTR2A, PTGS2 |
2.61843 |
|
[BP] GO:0046889 |
None
|
FABP3, HTR2A, HTR2B, PRKCD, PTGS2 |
2.60382 |
|
[BP] GO:0009266 |
None
|
ADORA1, ADRB1, HSPA1A, HTR2A, HTR2B, PTGS2, TRPV1 |
2.60201 |
|
[BP] GO:0071456 |
cellular response to hypoxia
|
BCL2, HIF1A, PRKCE, PTGS2, SRC, TERT |
2.58842 |
|
[BP] GO:0009653 |
anatomical structure morphogenesis
|
APP, AR, AXL, BCL2, CA2, CA9, CACNA1C, CYP1B1, DRD2, EGFR, ESR1, GAA, GBA, HIF1A, HTR2B, INSR, MET, MMP2, POLB, SMAD3, SRC, TEK |
2.57297 |
|
[BP] GO:1903580 |
None
|
ESRRB, HIF1A, HTR2A, INSR |
2.56972 |
|
[BP] GO:0001819 |
positive regulation of cytokine production
|
CYP1B1, DRD2, HIF1A, HSPA1A, HTR2B, IDO1, MIF, MMP12, PTGS2, SMAD3, SRC |
2.56862 |
|
[BP] GO:0031331 |
positive regulation of cellular catabolic process
|
ESRRB, GBA, HIF1A, HSPA1A, HTR2A, INSR, KDR, PIK3CB, PPARA, PRKCD, PTPN1 |
2.56862 |
|
[BP] GO:0043281 |
regulation of cysteine-type endopeptidase activity involved in apoptotic process
|
CSNK2A1, F3, GPER1, MMP9, PTGS2, SMAD3, SRC, XDH |
2.56007 |
|
[BP] GO:0006703 |
estrogen biosynthetic process
|
CYP19A1, HSD17B1, HSD17B2 |
2.56007 |
|
[BP] GO:0060134 |
None
|
DRD1, DRD2, DRD3 |
2.56007 |
|
[BP] GO:0001516 |
None
|
MIF, PTGS1, PTGS2 |
2.56007 |
|
[BP] GO:0060158 |
None
|
DRD1, DRD2, DRD5 |
2.56007 |
|
[BP] GO:0046457 |
None
|
MIF, PTGS1, PTGS2 |
2.56007 |
|
[BP] GO:2000026 |
regulation of multicellular organismal development
|
APP, AR, AXL, BCL2, CA2, CDK6, CYP1B1, DRD2, DRD3, EGFR, ERBB2, ESR1, ESRRA, F3, GPER1, HIF1A, IDO1, INSR, KDR, PIM1, PRKCA, PRKCB, PTGS2, SMAD3, SRC, TEK, TERT, XDH |
2.55897 |
|
[BP] GO:1905475 |
None
|
AR, BCL2, CSNK2A1, EGFR, ERBB2, GPER1, PRKCE |
2.5572 |
|
[BP] GO:1901653 |
cellular response to peptide
|
AKR1B1, APEX1, APP, GPER1, IGF1R, INSR, PRKCD, SRC |
2.53673 |
|
[BP] GO:0006721 |
terpenoid metabolic process
|
AKR1B10, CYP1A1, CYP1A2, CYP1B1, CYP2D6, EGFR |
2.53033 |
|
[BP] GO:1903829 |
positive regulation of cellular protein localization
|
APP, BCL2, EGFR, ERBB2, GPER1, PRKCD, PRKCE, PTGS2, SMAD3, SRC, TERT |
2.52876 |
|
[BP] GO:0006110 |
None
|
ESRRB, HIF1A, HTR2A, INSR, PPARA |
2.52217 |
|
[BP] GO:1900076 |
regulation of cellular response to insulin stimulus
|
ESRRA, PRKCB, PRKCD, PTPN1, SRC |
2.52217 |
|
[BP] GO:0046486 |
glycerolipid metabolic process
|
ACHE, ALPI, CSNK2A1, DRD2, EGFR, ERBB2, FABP3, FABP4, MET, PIK3CA, PIK3CB |
2.49396 |
|
[BP] GO:0032465 |
None
|
AURKB, CDC25B, DRD2, DRD3, PRKCE |
2.49396 |
|
[BP] GO:0035304 |
regulation of protein dephosphorylation
|
ADORA1, DRD2, GBA, NUAK1, PRKCD |
2.49396 |
|
[BP] GO:0002683 |
negative regulation of immune system process
|
ADORA1, AXL, CDK6, CYP19A1, DRD2, DUSP3, ERBB2, GPER1, IDO1, MIF, MMP12 |
2.4762 |
|
[BP] GO:0060065 |
uterus development
|
CYP19A1, ESR1, SRC |
2.46925 |
|
[BP] GO:0051580 |
None
|
DRD1, DRD2, DRD3 |
2.46925 |
|
[BP] GO:0051967 |
None
|
ADORA1, DRD2, HTR2A |
2.46925 |
|
[BP] GO:0019377 |
None
|
FUCA1, GBA, GBA2 |
2.46925 |
|
[BP] GO:0042180 |
None
|
AKR1B1, AKR1B10, CYP19A1, GLO1, IDO1 |
2.46881 |
|
[BP] GO:0019538 |
protein metabolic process
|
ACHE, ALPI, ALPL, APP, AR, AURKB, AXL, BACE1, BCL2, CDC25B, CDK6, CSNK2A1, DRD1, DUSP3, DYRK1A, EGFR, ERBB2, ESR1, F3, FLT3, FUT7, HIF1A, HTR2B, IGF1R, INSR, KDR, MET, MMP1, MMP12, MMP2, MMP9, NUAK1, PIK3CA, PIM1, POLB, PPARA, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, PTPN1, SMAD3, SRC, TEK, TNKS, TNKS2, TOP2A |
2.46214 |
|
[BP] GO:0033554 |
cellular response to stress
|
AKR1B1, APEX1, AXL, BCL2, CA2, CA9, CYP1B1, EGFR, GBA, HIF1A, HSPA1A, MIF, MMP9, NUAK1, POLA1, POLB, PRKCD, PRKCE, PTGS2, PTPN1, SRC, TERT, TOP2A, TRPV1 |
2.45958 |
|
[BP] GO:0036294 |
cellular response to decreased oxygen levels
|
BCL2, HIF1A, PRKCE, PTGS2, SRC, TERT |
2.45368 |
|
[BP] GO:0007212 |
None
|
DRD1, DRD2, DRD3, DRD5 |
2.44525 |
|
[BP] GO:0046456 |
icosanoid biosynthetic process
|
ALOX5, MIF, PTGS1, PTGS2 |
2.44525 |
|
[BP] GO:1903524 |
None
|
ADRA1A, ADRB1, EGFR, HTR2A, PTGS2 |
2.44281 |
|
[BP] GO:0044248 |
cellular catabolic process
|
ACHE, AKR1B10, ALDH2, AOX1, AURKB, CSNK2A1, CYP1A1, CYP1A2, CYP1B1, CYP2A6, CYP2D6, DAO, FABP3, FABP4, FUCA1, GAA, GBA, GBA2, HSPA1A, IDO1, MGAM, PIK3CB, SRC, XDH |
2.43161 |
|
[BP] GO:1901214 |
regulation of neuron death
|
AXL, BCL2, GBA, HIF1A, PIK3CA, PPARA, PRKCG, SIGMAR1, TERT |
2.42111 |
|
[BP] GO:0070848 |
response to growth factor
|
APP, EGFR, ERBB2, INSR, KDR, NR3C1, SMAD3, SRC, TRPV1 |
2.4106 |
|
[BP] GO:0014075 |
None
|
DRD1, DRD2, DRD3, DRD5 |
2.40429 |
|
[BP] GO:0015695 |
None
|
SLC22A1, SLC22A2, SLC22A3, SLC47A1 |
2.40429 |
|
[BP] GO:0042737 |
drug catabolic process
|
ACHE, ALDH2, CYP1A2, CYP2A6, CYP2D6, DAO |
2.39802 |
|
[BP] GO:0001503 |
ossification
|
ALPL, BCL2, EGFR, MMP2, MMP9, TEK |
2.39802 |
|
[BP] GO:0048010 |
vascular endothelial growth factor receptor signaling pathway
|
AXL, KDR, PIK3CA, PIK3CB, SRC |
2.39187 |
|
[BP] GO:0050965 |
None
|
ADORA1, HTR2A, TRPV1 |
2.38907 |
|
[BP] GO:0050961 |
None
|
ADORA1, HTR2A, TRPV1 |
2.38907 |
|
[BP] GO:0070198 |
None
|
TERT, TNKS, TNKS2 |
2.38907 |
|
[BP] GO:0060748 |
None
|
AR, PGR |
2.38176 |
|
[BP] GO:0098502 |
DNA dephosphorylation
|
APEX1, POLB |
2.38176 |
|
[BP] GO:0001996 |
None
|
ADRA1A, ADRB1 |
2.38176 |
|
[BP] GO:0000023 |
None
|
GAA, MGAM |
2.38176 |
|
[BP] GO:0046110 |
None
|
AOX1, XDH |
2.38176 |
|
[BP] GO:0023021 |
None
|
GBA, PRKCD |
2.38176 |
|
[BP] GO:0060160 |
None
|
DRD2, DRD3 |
2.38176 |
|
[BP] GO:0032849 |
positive regulation of cellular pH reduction
|
CA2, CA7 |
2.38176 |
|
[BP] GO:0003099 |
None
|
ADRA1A, ADRB1 |
2.38176 |
|
[BP] GO:0002520 |
None
|
CACNA1C, SMAD3 |
2.38176 |
|
[BP] GO:0003073 |
None
|
AR, DRD3, DRD5, HSD11B2 |
2.37687 |
|
[BP] GO:1904705 |
regulation of vascular smooth muscle cell proliferation
|
GPER1, MMP2, MMP9, TERT |
2.37687 |
|
[BP] GO:0051093 |
None
|
ADRB1, APP, BCL2, CDK6, DRD3, EGFR, ERBB2, ESRRB, GPER1, HIF1A, MIF, PPARA, SMAD3, TEK, TERT, TRPV1, XDH |
2.37411 |
|
[BP] GO:0016311 |
None
|
ALPI, ALPL, APEX1, BCL2, CA3, CDC25B, DUSP3, POLB, PTPN1 |
2.37289 |
|
[BP] GO:0051051 |
negative regulation of transport
|
ADORA1, APP, BCL2, DRD2, DRD3, GPR35, HSPA1A, HTR2A, MMP9, PRKCB, PRKCE, PTGS2 |
2.36199 |
|
[BP] GO:0009314 |
response to radiation
|
APP, AURKB, BCL2, DRD1, DRD2, DRD3, EGFR, HIF1A, POLB, PTGS2, TYR |
2.36148 |
|
[BP] GO:0048534 |
hematopoietic or lymphoid organ development
|
BCL2, FLT3, HIF1A, KDR, POLB, TEK, TYR |
2.36019 |
|
[BP] GO:0051345 |
None
|
ADRA1A, ADRB1, APP, EGFR, ERBB2, ESR1, F3, GPER1, HSPA1A, HTR2A, HTR2B, PRKCD, PTPN1, SMAD3, XDH |
2.35125 |
|
[BP] GO:1904062 |
None
|
APP, CACNA1C, DRD1, DRD2, DRD3, GPER1, GPR35, MMP9, PRKCE |
2.34283 |
|
[BP] GO:0048729 |
tissue morphogenesis
|
AR, BCL2, CA2, CA9, EGFR, ESR1, HIF1A, MET, SMAD3, SRC |
2.33146 |
|
[BP] GO:0051924 |
regulation of calcium ion transport
|
BCL2, CACNA1C, DRD1, DRD2, GPER1, GPR35, PRKCE, PTGS2 |
2.33146 |
|
[BP] GO:0043470 |
None
|
ESRRB, HIF1A, HTR2A, INSR, PPARA |
2.33115 |
|
[BP] GO:0032413 |
None
|
DRD2, DRD3, GPR35, MMP9, PRKCE |
2.33115 |
|
[BP] GO:0045944 |
None
|
APP, AR, DRD2, DRD3, EGFR, ESR1, ESRRA, ESRRB, GPER1, HIF1A, MET, MMP12, NR3C1, PGR, PPARA, SMAD3, TERT, TNKS, TOP2A |
2.331 |
|
[BP] GO:2000811 |
negative regulation of anoikis
|
BCL2, PIK3CA, SRC |
2.32764 |
|
[BP] GO:0032075 |
None
|
HSPA1A, PRKCD, PTPN1 |
2.32764 |
|
[BP] GO:0071071 |
None
|
FABP3, HTR2A, HTR2B |
2.32764 |
|
[BP] GO:0030540 |
female genitalia development
|
AXL, CYP19A1, ESR1 |
2.32764 |
|
[BP] GO:0070920 |
None
|
EGFR, ESR1, TERT |
2.32764 |
|
[BP] GO:0048546 |
None
|
BCL2, EGFR, HIF1A |
2.32764 |
|
[BP] GO:0002684 |
positive regulation of immune system process
|
APP, AXL, BCL2, CA2, HCAR2, HIF1A, HSPA1A, IDO1, MIF, MMP12, MMP2, PIK3CA, PIK3CB, PRKCA, PRKCB, PRKCD, PRKCE, SRC |
2.31872 |
|
[BP] GO:0022898 |
None
|
ABCB1, APP, BCL2, DRD2, DRD3, GPR35, MMP9, PRKCE |
2.31351 |
|
[BP] GO:0051952 |
None
|
ADORA1, DRD1, DRD2, DRD3, HTR2A |
2.31159 |
|
[BP] GO:0009268 |
None
|
CA2, GBA, SRC, TRPV1 |
2.30947 |
|
[BP] GO:0033574 |
response to testosterone
|
AR, CA9, CSNK2A1, GBA |
2.30947 |
|
[BP] GO:0009991 |
response to extracellular stimulus
|
ALPL, AXL, BCL2, CYP1A1, EGFR, GBA, HSD11B2, PTGS2, SRC, TRPV1, TYR |
2.28961 |
|
[BP] GO:0042060 |
None
|
DRD5, EGFR, ERBB2, PPARA, SMAD3 |
2.28768 |
|
[BP] GO:0044242 |
None
|
AKR1B10, CYP1B1, FABP3, FABP4, FUCA1, GBA, GBA2 |
2.2826 |
|
[BP] GO:0043467 |
regulation of generation of precursor metabolites and energy
|
ESRRB, HIF1A, HTR2A, INSR, PIK3CA, PPARA |
2.27327 |
|
[BP] GO:0006954 |
inflammatory response
|
ADORA1, ADORA3, AXL, GPER1, MIF, PIK3CA, PIK3CB, POLB, PTGS1, PTGS2, TRPV1 |
2.2665 |
|
[BP] GO:0033043 |
regulation of organelle organization
|
AURKB, BCL2, DNMT1, DRD3, GBA, GPER1, HIF1A, HSPA1A, INSR, KDR, MET, MMP9, PRKCD, PRKCE, SMAD3, SRC, TEK, TNKS, TNKS2, TOP2A |
2.25935 |
|
[BP] GO:0008631 |
intrinsic apoptotic signaling pathway in response to oxidative stress
|
BCL2, CYP1B1, PRKCD |
2.25589 |
|
[BP] GO:1904355 |
positive regulation of telomere capping
|
AURKB, TNKS, TNKS2 |
2.25589 |
|
[BP] GO:0050794 |
regulation of cellular process
|
ACHE, ADORA1, ADORA3, ADRA1A, ADRB1, AKR1B1, APEX1, APP, AR, AURKB, AXL, BACE1, BCL2, CA1, CA2, CA7, CA9, CACNA1C, CDC25B, CDK6, CSNK2A1, CYP19A1, CYP1A1, CYP1B1, CYP2D6, DNMT1, DRD1, DRD2, DRD3, DRD5, DUSP3, DYRK1A, EGFR, ERBB2, ESR1, ESR2, ESRRA, ESRRB, F3, FABP3, FABP4, FLT3, GBA, GLO1, GPER1, GPR35, HCAR2, HIF1A, HSPA1A, HTR1A, HTR2A, HTR2B, HTR5A, HTR6, HTR7, IDO1, IGF1R, INSR, KDR, MET, MIF, MMP1, MMP12, MMP2, MMP9, NR3C1, NR3C2, NUAK1, PGR, PIK3CA, PIK3CB, PIM1, POLA1, POLB, PPARA, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, PTGS1, PTGS2, PTPN1, RORC, SIGMAR1, SMAD3, SRC, TEK, TERT, TNKS, TNKS2, TOP2A, TRPV1, XDH |
2.25094 |
|
[BP] GO:0001961 |
None
|
AXL, HIF1A, HSPA1A, MMP12 |
2.23563 |
|
[BP] GO:2000116 |
regulation of cysteine-type endopeptidase activity
|
CSNK2A1, F3, GPER1, MMP9, PTGS2, SMAD3, SRC, XDH |
2.22181 |
|
[BP] GO:0006720 |
isoprenoid metabolic process
|
AKR1B10, CYP1A1, CYP1A2, CYP1B1, CYP2D6, EGFR |
2.22156 |
|
[BP] GO:1903076 |
None
|
AR, CSNK2A1, EGFR, GPER1, PRKCE |
2.21756 |
|
[BP] GO:0006694 |
steroid biosynthetic process
|
AKR1B1, CYP19A1, HSD11B1, HSD11B2, HSD17B1, HSD17B2 |
2.2039 |
|
[BP] GO:0007626 |
None
|
APP, DRD1, DRD2, DRD3, GAA, IDO1, PRKCE |
2.20049 |
|
[BP] GO:0043536 |
positive regulation of blood vessel endothelial cell migration
|
HIF1A, KDR, PRKCA, PTGS2 |
2.20049 |
|
[BP] GO:0050999 |
None
|
EGFR, HIF1A, HTR2B, TERT |
2.20049 |
|
[BP] GO:0032963 |
collagen metabolic process
|
HIF1A, MMP1, MMP12, MMP2, MMP9 |
2.19507 |
|
[BP] GO:0071453 |
cellular response to oxygen levels
|
BCL2, HIF1A, PRKCE, PTGS2, SRC, TERT |
2.18811 |
|
[BP] GO:0072488 |
None
|
SLC22A1, SLC22A2, SLC22A3 |
2.18681 |
|
[BP] GO:0051000 |
None
|
HIF1A, HTR2B, TERT |
2.18681 |
|
[BP] GO:0014821 |
None
|
DRD1, DRD2, HTR2B |
2.18681 |
|
[BP] GO:0071702 |
None
|
ABCB1, ABCG2, ADORA1, CA1, CA12, CA14, CA2, CA3, CA4, CA5A, CA5B, CA6, CA7, CA9, DRD1, DRD2, DRD3, FABP3, MMP12, PPARA, PRKCB, SIGMAR1, SLC22A1, SLC22A2, SLC22A3, SLC47A1, TNKS, TRPV1 |
2.18173 |
|
[BP] GO:0033273 |
response to vitamin
|
ALPL, CYP1A1, EGFR, PTGS2, TYR |
2.17459 |
|
[BP] GO:1903426 |
None
|
EGFR, INSR, PTGS2, SMAD3, TRPV1 |
2.17459 |
|
[BP] GO:0006816 |
None
|
ADRA1A, CACNA1C, DRD2, HTR2A, HTR2B, PRKCB, PRKCE, TRPV1 |
2.16962 |
|
[BP] GO:0045761 |
None
|
DRD2, DRD3, DRD5, PRKCA |
2.16962 |
|
[BP] GO:0001954 |
positive regulation of cell-matrix adhesion
|
CDK6, KDR, SMAD3, TEK |
2.16962 |
|
[BP] GO:0097366 |
None
|
DRD1, DRD2, DRD3, DRD5 |
2.16962 |
|
[BP] GO:0046903 |
None
|
ALOX5, APP, AXL, CA2, CA9, DRD2, DRD3, FUCA1, GAA, HIF1A, HSPA1A, MGAM, MIF, MMP9, PRKCD, SLC22A2, TRPV1, XDH |
2.16016 |
|
[BP] GO:0038127 |
None
|
EGFR, ERBB2, PIK3CA, PRKCA, SRC |
2.15525 |
|
[BP] GO:0032410 |
None
|
DRD2, DRD3, GPR35, MMP9, PRKCE |
2.15525 |
|
[BP] GO:1904063 |
None
|
DRD2, DRD3, GPR35, MMP9, PRKCE |
2.15525 |
|
[BP] GO:0045595 |
regulation of cell differentiation
|
APP, AR, AXL, BCL2, CA2, CDK6, DRD2, DRD3, EGFR, ERBB2, ESRRA, ESRRB, GPER1, HIF1A, HTR2A, KDR, PPARA, PRKCA, PRKCB, PTGS2, RORC, SMAD3, TERT, TRPV1, XDH |
2.15525 |
|
[BP] GO:0046683 |
response to organophosphorus
|
APEX1, APP, PTGS2, TEK, TRPV1, TYR |
2.14436 |
|
[BP] GO:0090342 |
None
|
CDK6, MIF, NUAK1, TERT |
2.13791 |
|
[BP] GO:1901989 |
None
|
APEX1, APP, CDC25B, CYP1A1, TERT |
2.1347 |
|
[BP] GO:0033135 |
regulation of peptidyl-serine phosphorylation
|
APP, BCL2, EGFR, MIF, PIK3CA, PTGS2 |
2.1347 |
|
[BP] GO:0098908 |
None
|
GBA, GPR35 |
2.1347 |
|
[BP] GO:1901374 |
None
|
SLC22A1, SLC22A2 |
2.1347 |
|
[BP] GO:0001994 |
None
|
ADRA1A, DRD5 |
2.1347 |
|
[BP] GO:0033031 |
positive regulation of neutrophil apoptotic process
|
HCAR2, PIK3CB |
2.1347 |
|
[BP] GO:0070213 |
None
|
TNKS, TNKS2 |
2.1347 |
|
[BP] GO:0006145 |
None
|
AOX1, XDH |
2.1347 |
|
[BP] GO:0015874 |
None
|
SLC22A1, SLC22A2 |
2.1347 |
|
[BP] GO:0018894 |
dibenzo-p-dioxin metabolic process
|
CYP1A1, CYP1A2 |
2.1347 |
|
[BP] GO:0045187 |
None
|
ADORA1, DRD2, DRD3 |
2.13463 |
|
[BP] GO:0016048 |
None
|
ADORA1, HTR2A, TRPV1 |
2.13463 |
|
[BP] GO:0051900 |
regulation of mitochondrial depolarization
|
BCL2, KDR, SRC |
2.13463 |
|
[BP] GO:0007617 |
None
|
APP, DRD1, DRD5 |
2.13463 |
|
[BP] GO:0060191 |
regulation of lipase activity
|
ADRA1A, EGFR, ESR1, HTR2A, HTR2B |
2.12079 |
|
[BP] GO:0060760 |
None
|
AXL, HIF1A, HSPA1A, MMP12 |
2.11347 |
|
[BP] GO:0032147 |
activation of protein kinase activity
|
ADORA1, DRD2, EGFR, INSR, PIK3CA, PIK3CB, PRKCD, PTPN1, SRC |
2.10279 |
|
[BP] GO:0044259 |
multicellular organismal macromolecule metabolic process
|
HIF1A, MMP1, MMP12, MMP2, MMP9 |
2.09926 |
|
[BP] GO:0042058 |
None
|
ADORA1, APP, EGFR, GPER1, MMP9 |
2.09926 |
|
[BP] GO:0001817 |
regulation of cytokine production
|
AXL, CYP1B1, DRD2, GBA, HIF1A, HSPA1A, HTR2B, IDO1, MIF, MMP12, PTGS2, SMAD3, SRC |
2.09387 |
|
[BP] GO:0010468 |
regulation of gene expression
|
ADORA3, APEX1, APP, AR, AURKB, BCL2, CA9, CDK6, CSNK2A1, CYP1A2, CYP1B1, DNMT1, DRD1, DRD2, DRD3, DYRK1A, EGFR, ERBB2, ESR1, ESR2, ESRRA, ESRRB, FABP4, GLO1, GPER1, HIF1A, HSPA1A, INSR, KDR, MET, MIF, MMP12, NR3C1, NR3C2, PGR, PIK3CA, PIK3CB, PIM1, POLA1, PPARA, PRKCA, PRKCB, PRKCD, RORC, SMAD3, SRC, TERT, TNKS, TOP2A, TRPV1, XDH |
2.08136 |
|
[BP] GO:0001892 |
None
|
EGFR, ESRRB, HIF1A |
2.07259 |
|
[BP] GO:0035813 |
None
|
ADORA1, DRD2, DRD3 |
2.07259 |
|
[BP] GO:0071880 |
None
|
ADRA1A, ADRB1, DRD2 |
2.07259 |
|
[BP] GO:0051196 |
None
|
ESRRB, HIF1A, HTR2A, INSR, PPARA |
2.05813 |
|
[BP] GO:0051341 |
None
|
DRD5, EGFR, HIF1A, HTR2B, TERT |
2.05813 |
|
[BP] GO:1904375 |
None
|
AR, CSNK2A1, EGFR, GPER1, PRKCE |
2.05813 |
|
[BP] GO:2000351 |
None
|
GPER1, KDR, TEK, TERT |
2.05171 |
|
[BP] GO:0046626 |
regulation of insulin receptor signaling pathway
|
PRKCB, PRKCD, PTPN1, SRC |
2.05171 |
|
[BP] GO:0035306 |
None
|
ADORA1, GBA, PRKCD, SMAD3 |
2.05171 |
|
[BP] GO:2001023 |
None
|
DRD1, DRD2, DRD3, HTR2A, MET |
2.03746 |
|
[BP] GO:0043524 |
negative regulation of neuron apoptotic process
|
AXL, BCL2, HIF1A, PIK3CA, PRKCG, TERT |
2.027 |
|
[BP] GO:0043523 |
regulation of neuron apoptotic process
|
AXL, BCL2, HIF1A, PIK3CA, PRKCG, SIGMAR1, TERT |
2.02438 |
|
[BP] GO:0097755 |
None
|
ADRB1, DRD1, EGFR, GPER1 |
2.02038 |
|
[BP] GO:0051588 |
None
|
DRD1, DRD2, DRD3, GPER1, HTR1A |
2.01759 |
|
[BP] GO:0048609 |
multicellular organismal reproductive process
|
AKR1B1, APP, AR, AXL, CYP1A1, DRD1, DRD5, EGFR, ESR1, PGR, PTGS2, SRC |
2.01681 |
|
[BP] GO:0071498 |
cellular response to fluid shear stress
|
CA2, PTGS2, SRC |
2.01681 |
|
[BP] GO:0051968 |
None
|
DRD1, EGFR, PTGS2 |
2.01681 |
|
[BP] GO:0042749 |
None
|
ADORA1, DRD2, DRD3 |
2.01681 |
|
[BP] GO:0050877 |
None
|
ADORA1, APP, CYP1B1, DRD1, DRD2, DRD3, DRD5, EGFR, GAA, HIF1A, HTR2A, INSR, PRKCG, PTGS2, TRPV1, TYR |
2.01681 |
|
[CC] GO:0005886 |
plasma membrane
|
ABCB1, ABCG2, ACHE, ADORA1, ADORA3, ADRA1A, ADRB1, ALPI, ALPL, APP, AR, AXL, BACE1, CA12, CA14, CA2, CA4, CA9, CACNA1C, CSNK2A1, DRD1, DRD2, DRD3, DRD5, EGFR, ERBB2, ESR1, F3, FLT3, GAA, GBA2, GLO1, GPER1, GPR35, HCAR2, HTR1A, HTR2A, HTR2B, HTR5A, HTR6, HTR7, IGF1R, INSR, KDR, MET, MGAM, MMP2, PIK3CA, PIK3CB, PIM1, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, PTPN1, SLC22A1, SLC22A2, SLC22A3, SLC47A1, SLC47A2, SMAD3, SRC, TEK, TERT, TRPV1 |
8.78693 |
|
[CC] GO:0016020 |
membrane
|
ABCB1, ABCG2, ACHE, ADORA1, ADORA3, ADRA1A, ADRB1, ALOX5, ALPI, ALPL, APP, AR, AXL, BACE1, BCL2, CA12, CA14, CA2, CA4, CA9, CACNA1C, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, CYP2D6, DAO, DRD1, DRD2, DRD3, DRD5, EGFR, ERBB2, ESR1, F3, FLT3, FUT7, GAA, GBA, GBA2, GLO1, GPER1, GPR35, HCAR2, HSD11B1, HSD11B2, HSD17B2, HTR1A, HTR2A, HTR2B, HTR5A, HTR6, HTR7, IGF1R, INSR, KDR, MET, MGAM, MMP2, NR3C2, PGR, PIK3CA, PIK3CB, PIM1, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, PTGS1, PTGS2, PTPN1, SIGMAR1, SLC22A1, SLC22A2, SLC22A3, SLC47A1, SLC47A2, SMAD3, SRC, TBXAS1, TEK, TERT, TNKS, TNKS2, TRPV1, TYR |
7.91573 |
|
[CC] GO:0031226 |
intrinsic component of plasma membrane
|
ADORA1, ADORA3, ADRA1A, ADRB1, APP, AXL, BACE1, CA4, DRD1, DRD2, DRD3, DRD5, F3, FLT3, GPER1, GPR35, HTR1A, HTR2A, HTR2B, HTR5A, HTR6, HTR7, IGF1R, INSR, KDR, MET, SIGMAR1, SLC22A1, SLC22A2, SLC22A3, TEK, TRPV1 |
6.54205 |
|
[CC] GO:0044459 |
plasma membrane part
|
ABCB1, ABCG2, ADORA1, ADORA3, ADRA1A, ADRB1, APP, AXL, BACE1, CA2, CA4, CA9, CACNA1C, DRD1, DRD2, DRD3, DRD5, DUSP3, EGFR, ERBB2, F3, FLT3, GPER1, GPR35, HTR1A, HTR2A, HTR2B, HTR5A, HTR6, HTR7, IGF1R, INSR, KDR, MET, MGAM, PRKCG, PTGS2, SIGMAR1, SLC22A1, SLC22A2, SLC22A3, SRC, TEK, TRPV1 |
5.98321 |
|
[CC] GO:0005887 |
integral component of plasma membrane
|
ADORA1, ADORA3, ADRA1A, ADRB1, APP, AXL, BACE1, DRD1, DRD2, DRD3, DRD5, FLT3, GPER1, GPR35, HTR1A, HTR2A, HTR2B, HTR5A, HTR6, HTR7, IGF1R, INSR, KDR, MET, SIGMAR1, SLC22A1, SLC22A2, SLC22A3, TEK, TRPV1 |
5.86403 |
|
[CC] GO:0098590 |
plasma membrane region
|
ABCB1, ABCG2, ADORA1, ADRA1A, CA2, CA4, CA9, DRD1, DRD2, DRD5, EGFR, ERBB2, GPER1, HTR2A, INSR, MET, MGAM, PRKCG, PTGS2, SIGMAR1, SLC22A1, SRC, TEK, TRPV1 |
5.45272 |
|
[CC] GO:0044444 |
cytoplasmic part
|
ABCG2, ACHE, ADORA1, ADRA1A, ADRB1, AKR1B1, AKR1B10, ALDH2, ALOX5, AOX1, APEX1, APP, AR, AURKB, BACE1, BCL2, CA1, CA2, CA3, CA4, CA5A, CA5B, CA7, CACNA1C, CDC25B, CDK6, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, CYP2D6, DAO, DRD1, DRD2, DRD3, DUSP3, EGFR, ERBB2, ESR1, ESR2, FABP3, FABP4, FLT3, FUCA1, FUT7, GAA, GBA, GBA2, GLO1, GPER1, HIF1A, HSD11B1, HSD11B2, HSD17B1, HSD17B2, HSPA1A, HTR2A, HTR5A, IDO1, INSR, KDR, MGAM, MIF, MMP2, MMP9, NQO2, NR3C1, NR3C2, PGR, PIK3CA, PIK3CB, PIM1, POLA1, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, PTGS1, PTGS2, PTPN1, SIGMAR1, SMAD3, SRC, TBXAS1, TERT, TNKS, TNKS2, TOP2A, TRPV1, TYR, XDH |
5.36348 |
|
[CC] GO:0043227 |
membrane-bounded organelle
|
ABCB1, ABCG2, ACHE, ADORA1, ADRA1A, ADRB1, AKR1B1, AKR1B10, ALDH2, ALPL, AOX1, APEX1, APP, AR, AURKB, AXL, BACE1, BCL2, CA1, CA2, CA4, CA5A, CA5B, CA6, CDK6, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2D6, DAO, DNMT1, DRD1, DRD2, DRD3, DUSP3, DYRK1A, EGFR, ERBB2, ESR1, ESR2, ESRRA, ESRRB, F3, FABP3, FABP4, FLT3, FUCA1, FUT7, GAA, GBA, GBA2, GLO1, GPER1, HIF1A, HSPA1A, HTR2A, HTR5A, IGF1R, INSR, KDR, MGAM, MIF, MMP12, MMP2, MMP9, NQO2, NR3C1, NUAK1, PIK3CB, PIM1, POLA1, POLB, PPARA, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, PTGS1, PTGS2, PTPN1, RORC, SHBG, SIGMAR1, SLC22A2, SLC47A1, SMAD3, SRC, TERT, TNKS, TNKS2, TOP2A, TYR, XDH |
4.74184 |
|
[CC] GO:0044425 |
membrane part
|
ABCB1, ABCG2, ACHE, ADORA1, ADORA3, ADRA1A, ADRB1, ALPI, ALPL, APP, AXL, BACE1, BCL2, CA12, CA14, CA2, CA4, CA9, CACNA1C, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, CYP2D6, DRD1, DRD2, DRD3, DRD5, DUSP3, EGFR, ERBB2, ESR1, F3, FLT3, FUT7, GBA2, GPER1, GPR35, HCAR2, HSD11B1, HSD11B2, HSD17B2, HTR1A, HTR2A, HTR2B, HTR5A, HTR6, HTR7, IGF1R, INSR, KDR, MET, MGAM, NR3C2, PIK3CA, PIK3CB, PRKCG, PTGS1, PTGS2, PTPN1, SIGMAR1, SLC22A1, SLC22A2, SLC22A3, SLC47A1, SLC47A2, SRC, TBXAS1, TEK, TRPV1, TYR |
4.34616 |
|
[CC] GO:0043226 |
organelle
|
ABCB1, ABCG2, ACHE, ADORA1, ADRA1A, ADRB1, AKR1B1, AKR1B10, ALDH2, ALPL, AOX1, APEX1, APP, AR, AURKB, AXL, BACE1, BCL2, CA1, CA2, CA4, CA5A, CA5B, CA6, CA9, CACNA1C, CDK6, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2D6, DAO, DNMT1, DRD1, DRD2, DRD3, DRD5, DUSP3, DYRK1A, EGFR, ERBB2, ESR1, ESR2, ESRRA, ESRRB, F3, FABP3, FABP4, FLT3, FUCA1, FUT7, GAA, GBA, GBA2, GLO1, GPER1, HIF1A, HSPA1A, HTR2A, HTR5A, HTR6, IDO1, IGF1R, INSR, KDR, MGAM, MIF, MMP12, MMP2, MMP9, NQO2, NR3C1, NUAK1, PIK3CB, PIM1, POLA1, POLB, PPARA, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, PTGS1, PTGS2, PTPN1, RORC, SHBG, SIGMAR1, SLC22A2, SLC47A1, SMAD3, SRC, TERT, TNKS, TNKS2, TOP2A, TYR, XDH |
4.28107 |
|
[CC] GO:0005789 |
endoplasmic reticulum membrane
|
BCL2, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, CYP2D6, DRD1, EGFR, GBA2, GPER1, HSD11B1, HSD11B2, HSD17B2, NR3C2, PTGS1, PTGS2, SIGMAR1, TBXAS1 |
3.69658 |
|
[CC] GO:0005783 |
None
|
ADORA1, APEX1, APP, BCL2, CA4, CYP19A1, CYP2D6, FLT3, GBA2, GPER1, HSPA1A, HTR5A, KDR, PRKCA, PRKCD, PRKCE, PTGS2, PTPN1, SIGMAR1, XDH |
3.5498 |
|
[CC] GO:0044432 |
endoplasmic reticulum part
|
APP, BACE1, BCL2, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, CYP2D6, DRD1, EGFR, FLT3, GBA2, GPER1, HSD11B1, HSD11B2, HSD17B2, NR3C2, PTGS1, PTGS2, PTPN1, SIGMAR1, TBXAS1 |
3.5416 |
|
[CC] GO:0048471 |
perinuclear region of cytoplasm
|
ACHE, AKR1B1, APEX1, APP, CA4, EGFR, ERBB2, GPER1, HSPA1A, PRKCA, PRKCD, PRKCE, PRKCG, SRC, TNKS2, TYR |
3.40674 |
|
[CC] GO:0044464 |
cell part
|
ABCB1, ABCG2, ACHE, ADORA1, ADORA3, ADRA1A, ADRB1, AKR1B1, AKR1B10, ALDH2, ALOX5, ALPI, ALPL, AOX1, APEX1, APP, AR, AURKB, AXL, BACE1, BCL2, CA1, CA12, CA14, CA2, CA3, CA4, CA5A, CA5B, CA7, CA9, CACNA1C, CDC25B, CDK6, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, CYP2D6, DAO, DNMT1, DRD1, DRD2, DRD3, DRD5, DUSP3, DYRK1A, EGFR, ERBB2, ESR1, ESR2, ESRRA, ESRRB, F3, FABP3, FABP4, FLT3, FUCA1, FUT7, GAA, GBA, GBA2, GLO1, GPER1, GPR35, HCAR2, HIF1A, HSD11B1, HSD11B2, HSD17B1, HSD17B2, HSPA1A, HTR1A, HTR2A, HTR2B, HTR5A, HTR6, HTR7, IDO1, IGF1R, INSR, KDR, MET, MGAM, MIF, MMP12, MMP2, MMP9, NQO2, NR3C1, NR3C2, NUAK1, PGR, PIK3CA, PIK3CB, PIM1, POLA1, POLB, PPARA, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, PTGS1, PTGS2, PTPN1, RORC, SIGMAR1, SLC22A1, SLC22A2, SLC22A3, SLC47A1, SLC47A2, SMAD3, SRC, TBXAS1, TEK, TERT, TNKS, TNKS2, TOP2A, TRPV1, TYR, XDH |
3.31141 |
|
[CC] GO:0045121 |
membrane raft
|
ADRA1A, APP, BACE1, EGFR, HTR2A, INSR, KDR, PTGS2, SRC, TEK |
2.9058 |
|
[CC] GO:0098857 |
membrane microdomain
|
ADRA1A, APP, BACE1, EGFR, HTR2A, INSR, KDR, PTGS2, SRC, TEK |
2.8823 |
|
[CC] GO:0016323 |
basolateral plasma membrane
|
ADORA1, CA2, CA4, CA9, EGFR, ERBB2, SLC22A1, TEK |
2.81616 |
|
[CC] GO:0044422 |
organelle part
|
ABCG2, ADRA1A, AKR1B1, ALDH2, ALOX5, AOX1, APEX1, APP, AR, AURKB, BACE1, BCL2, CA4, CA5A, CA5B, CA9, CACNA1C, CDC25B, CDK6, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, CYP2D6, DAO, DNMT1, DRD1, DRD2, DRD5, DUSP3, DYRK1A, EGFR, ERBB2, ESR1, ESR2, ESRRA, ESRRB, FLT3, FUCA1, FUT7, GAA, GBA, GBA2, GPER1, HIF1A, HSD11B1, HSD11B2, HSD17B2, HSPA1A, IDO1, INSR, MGAM, MIF, MMP2, MMP9, NQO2, NR3C1, NR3C2, NUAK1, PGR, PIK3CB, PIM1, POLA1, POLB, PPARA, PRKCA, PRKCB, PRKCD, PTGS1, PTGS2, PTPN1, RORC, SIGMAR1, SMAD3, SRC, TBXAS1, TEK, TERT, TNKS, TNKS2, TOP2A, TYR |
2.77861 |
|
[CC] GO:0031982 |
None
|
ABCB1, ADRB1, AKR1B1, AKR1B10, ALDH2, ALPL, AOX1, APP, AXL, BACE1, CA1, CA2, CA4, CA6, DRD2, DRD3, DUSP3, EGFR, F3, FABP3, FABP4, FUCA1, GAA, GBA, GLO1, GPER1, HSPA1A, HTR2A, INSR, KDR, MGAM, MIF, MMP9, NQO2, PRKCA, PRKCB, PRKCD, PTGS1, PTPN1, SHBG, SIGMAR1, SLC22A2, SLC47A1, SRC, TYR |
2.71902 |
|
[CC] GO:0031253 |
None
|
ADORA1, CA4, CA9, DRD1, DRD2, DRD5, GPER1, INSR, SRC, TRPV1 |
2.68699 |
|
[CC] GO:0031090 |
None
|
ABCG2, ADRA1A, ALOX5, APP, BACE1, BCL2, CA4, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, CYP2D6, DAO, DRD1, DRD2, DRD5, EGFR, ERBB2, FUT7, GAA, GBA, GBA2, GPER1, INSR, MGAM, PGR, PRKCA, PTGS1, PTGS2, SIGMAR1, SMAD3, SRC, TNKS, TNKS2, TYR |
2.64857 |
|
[CC] GO:0005901 |
caveola
|
ADRA1A, HTR2A, INSR, PTGS2, SRC |
2.41535 |
|
[CC] GO:0098589 |
membrane region
|
ADRA1A, APP, BACE1, EGFR, HTR2A, INSR, KDR, PTGS2, SRC, TEK |
2.34014 |
|
[CC] GO:0032589 |
None
|
ADORA1, GPER1, INSR, TRPV1 |
2.30947 |
|
[CC] GO:0005654 |
None
|
AKR1B1, ALOX5, APEX1, AR, AURKB, BCL2, CDC25B, CDK6, CSNK2A1, DNMT1, DUSP3, DYRK1A, ESR1, ESR2, ESRRA, ESRRB, HIF1A, HSPA1A, MIF, NQO2, NR3C1, NR3C2, NUAK1, PGR, PIM1, POLA1, POLB, PPARA, PRKCA, PRKCB, PRKCD, RORC, SMAD3, SRC, TERT, TNKS, TOP2A |
2.17827 |
|
[CC] GO:0044446 |
intracellular organelle part
|
ABCG2, ADRA1A, AKR1B1, ALDH2, ALOX5, AOX1, APEX1, APP, AR, AURKB, BACE1, BCL2, CA4, CA5A, CA5B, CA9, CDC25B, CDK6, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, CYP2D6, DAO, DNMT1, DRD1, DRD2, DUSP3, DYRK1A, EGFR, ERBB2, ESR1, ESR2, ESRRA, ESRRB, FLT3, FUCA1, FUT7, GAA, GBA, GBA2, GPER1, HIF1A, HSD11B1, HSD11B2, HSD17B2, HSPA1A, INSR, MGAM, MIF, MMP9, NQO2, NR3C1, NR3C2, NUAK1, PGR, PIK3CB, PIM1, POLA1, POLB, PPARA, PRKCA, PRKCB, PRKCD, PTGS1, PTGS2, PTPN1, RORC, SIGMAR1, SMAD3, SRC, TBXAS1, TEK, TERT, TNKS, TNKS2, TOP2A, TYR |
2.12576 |
|
[MF] GO:0046914 |
transition metal ion binding
|
ALOX5, ALPI, AOX1, APP, AR, CA1, CA12, CA2, CA3, CA4, CA5A, CA5B, CA6, CA7, CA9, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, CYP2D6, DNMT1, ESR1, ESR2, ESRRA, ESRRB, GLO1, MMP1, MMP12, MMP2, MMP9, NQO2, NR3C1, NR3C2, PGR, PIM1, PPARA, PRKCA, PRKCB, PRKCG, PTPN1, RORC, SMAD3, TBXAS1, TNKS, TYR, XDH |
22.0846 |
|
[MF] GO:0043167 |
ion binding
|
ABCB1, ABCG2, ACHE, ALOX5, ALPI, ALPL, AOX1, APEX1, APP, AR, AURKB, AXL, CA1, CA12, CA14, CA2, CA3, CA4, CA5A, CA5B, CA6, CA7, CA9, CACNA1C, CDK6, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, CYP2D6, DAO, DNMT1, DRD1, DRD2, DRD3, DRD5, DYRK1A, EGFR, ERBB2, ESR1, ESR2, ESRRA, ESRRB, F3, FABP3, FABP4, FLT3, GLO1, HSD17B1, HSPA1A, HTR1A, HTR2A, HTR2B, HTR5A, HTR7, IDO1, IGF1R, INSR, KDR, MET, MMP1, MMP12, MMP2, MMP9, NQO2, NR3C1, NR3C2, NUAK1, PGR, PIK3CA, PIK3CB, PIM1, POLA1, POLB, PPARA, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, PTGS1, PTGS2, PTPN1, RORC, SMAD3, SRC, TBXAS1, TEK, TERT, TNKS, TNKS2, TOP2A, TRPV1, TYR, XDH |
19.3018 |
|
[MF] GO:0004089 |
carbonate dehydratase activity
|
CA1, CA12, CA14, CA2, CA3, CA4, CA5A, CA5B, CA6, CA7, CA9 |
17.4232 |
|
[MF] GO:0003824 |
catalytic activity
|
ABCB1, ABCG2, ACHE, ADORA1, AKR1B1, AKR1B10, ALDH2, ALOX5, ALPI, ALPL, AOX1, APEX1, AURKB, AXL, BACE1, CA1, CA12, CA14, CA2, CA3, CA4, CA5A, CA5B, CA6, CA7, CA9, CDC25B, CDK6, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, CYP2D6, DAO, DNMT1, DUSP3, DYRK1A, EGFR, ERBB2, F3, FLT3, FUCA1, FUT7, GAA, GBA, GBA2, GLO1, HSD11B1, HSD11B2, HSD17B1, HSD17B2, HSPA1A, IDO1, IGF1R, INSR, KDR, MET, MGAM, MIF, MMP1, MMP12, MMP2, MMP9, NQO2, NUAK1, PIK3CA, PIK3CB, PIM1, POLA1, POLB, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, PTGS1, PTGS2, PTPN1, SRC, TBXAS1, TEK, TERT, TNKS, TNKS2, TOP2A, TYR, XDH |
15.0749 |
|
[MF] GO:0043169 |
cation binding
|
ACHE, ALOX5, ALPI, ALPL, AOX1, APEX1, APP, AR, AURKB, CA1, CA12, CA14, CA2, CA3, CA4, CA5A, CA5B, CA6, CA7, CA9, CACNA1C, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, CYP2D6, DNMT1, DRD1, DRD2, DRD3, DRD5, ESR1, ESR2, ESRRA, ESRRB, GLO1, HTR1A, HTR2A, HTR2B, HTR5A, HTR7, IDO1, MMP1, MMP12, MMP2, MMP9, NQO2, NR3C1, NR3C2, NUAK1, PGR, PIM1, POLA1, POLB, PPARA, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, PTGS1, PTGS2, PTPN1, RORC, SMAD3, TBXAS1, TERT, TNKS, TNKS2, TOP2A, TRPV1, TYR, XDH |
14.6417 |
|
[MF] GO:0008270 |
zinc ion binding
|
ALPI, AR, CA1, CA12, CA2, CA3, CA4, CA5A, CA5B, CA6, CA7, CA9, DNMT1, ESR1, ESR2, ESRRA, ESRRB, GLO1, MMP1, MMP12, MMP2, MMP9, NQO2, NR3C1, NR3C2, PGR, PPARA, PRKCA, PRKCB, PRKCG, PTPN1, RORC, SMAD3, TNKS |
14.0237 |
|
[MF] GO:0008144 |
drug binding
|
ABCB1, ABCG2, ACHE, AURKB, AXL, CDK6, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2D6, DRD1, DRD2, DRD3, DRD5, DYRK1A, EGFR, ERBB2, FLT3, HSPA1A, HTR2A, HTR2B, IGF1R, INSR, KDR, MET, NQO2, NUAK1, PIK3CA, PIK3CB, PIM1, PPARA, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, SIGMAR1, SRC, TEK, TOP2A, TRPV1 |
11.6417 |
|
[MF] GO:0016835 |
carbon-oxygen lyase activity
|
APEX1, CA1, CA12, CA14, CA2, CA3, CA4, CA5A, CA5B, CA6, CA7, CA9, POLB |
11.6332 |
|
[MF] GO:0038023 |
signaling receptor activity
|
ADORA1, ADORA3, ADRA1A, ADRB1, AR, AXL, DRD1, DRD2, DRD3, DRD5, EGFR, ERBB2, ESR1, ESR2, ESRRA, ESRRB, F3, FLT3, GPER1, GPR35, HCAR2, HTR1A, HTR2A, HTR2B, HTR5A, HTR6, HTR7, IGF1R, INSR, KDR, MET, NR3C1, NR3C2, PGR, PPARA, RORC, SIGMAR1, TEK, TRPV1 |
11.446 |
|
[MF] GO:0005496 |
steroid binding
|
AR, ESR1, ESR2, ESRRA, ESRRB, GPER1, HSD11B2, HSD17B1, NR3C1, NR3C2, PGR, RORC, SHBG |
10.9629 |
|
[MF] GO:0016836 |
hydro-lyase activity
|
CA1, CA12, CA14, CA2, CA3, CA4, CA5A, CA5B, CA6, CA7, CA9 |
10.4067 |
|
[MF] GO:0060089 |
molecular transducer activity
|
ADORA1, ADORA3, ADRA1A, ADRB1, AR, AXL, CDK6, DRD1, DRD2, DRD3, DRD5, EGFR, ERBB2, ESR1, ESR2, ESRRA, ESRRB, F3, FLT3, GPER1, GPR35, HCAR2, HTR1A, HTR2A, HTR2B, HTR5A, HTR6, HTR7, IGF1R, INSR, KDR, MET, NR3C1, NR3C2, PGR, PPARA, RORC, SIGMAR1, TEK, TRPV1 |
10.1488 |
|
[MF] GO:0003707 |
steroid hormone receptor activity
|
AR, ESR1, ESR2, ESRRA, ESRRB, GPER1, NR3C1, NR3C2, PGR, PPARA, RORC |
10.0998 |
|
[MF] GO:0004871 |
signal transducer activity
|
ADORA1, ADORA3, ADRA1A, ADRB1, AR, AXL, DRD1, DRD2, DRD3, DRD5, EGFR, ERBB2, ESR1, ESR2, ESRRA, ESRRB, F3, FLT3, GPER1, GPR35, HCAR2, HTR1A, HTR2A, HTR2B, HTR5A, HTR6, HTR7, IGF1R, INSR, KDR, MET, NR3C1, NR3C2, PGR, PPARA, PRKCE, RORC, SIGMAR1, SMAD3, TEK, TRPV1 |
9.9406 |
|
[MF] GO:0004872 |
receptor activity
|
ADORA1, ADORA3, ADRA1A, ADRB1, AR, AXL, DRD1, DRD2, DRD3, DRD5, EGFR, ERBB2, ESR1, ESR2, ESRRA, ESRRB, F3, FLT3, GPER1, GPR35, HCAR2, HTR1A, HTR2A, HTR2B, HTR5A, HTR6, HTR7, IGF1R, INSR, KDR, MET, NR3C1, NR3C2, PGR, PPARA, RORC, SIGMAR1, TEK, TRPV1 |
9.93806 |
|
[MF] GO:0046872 |
metal ion binding
|
ALOX5, ALPI, ALPL, AOX1, APEX1, APP, AR, AURKB, CA1, CA12, CA14, CA2, CA3, CA4, CA5A, CA5B, CA6, CA7, CA9, CACNA1C, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, CYP2D6, DNMT1, ESR1, ESR2, ESRRA, ESRRB, GLO1, IDO1, MMP1, MMP12, MMP2, MMP9, NQO2, NR3C1, NR3C2, NUAK1, PGR, PIM1, POLA1, POLB, PPARA, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, PTGS1, PTGS2, PTPN1, RORC, SMAD3, TBXAS1, TERT, TNKS, TNKS2, TOP2A, TRPV1, TYR, XDH |
9.60292 |
|
[MF] GO:0097159 |
organic cyclic compound binding
|
ABCB1, ABCG2, ADORA1, ADRB1, ALDH2, AOX1, APEX1, APP, AR, AURKB, AXL, BCL2, CDK6, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, CYP2D6, DAO, DNMT1, DRD1, DRD2, DRD3, DRD5, DYRK1A, EGFR, ERBB2, ESR1, ESR2, ESRRA, ESRRB, FLT3, GPER1, HIF1A, HSD11B2, HSD17B1, HSPA1A, HTR1A, HTR2A, HTR2B, HTR5A, HTR7, IDO1, IGF1R, INSR, KDR, MET, MMP12, NQO2, NR3C1, NR3C2, NUAK1, PGR, PIK3CA, PIK3CB, PIM1, POLA1, POLB, PPARA, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, PTGS1, PTGS2, PTPN1, RORC, SHBG, SMAD3, SRC, TBXAS1, TEK, TERT, TOP2A, TRPV1, XDH |
8.83684 |
|
[MF] GO:0016491 |
oxidoreductase activity
|
AKR1B1, AKR1B10, ALDH2, ALOX5, AOX1, APEX1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, CYP2D6, DAO, HSD11B1, HSD11B2, HSD17B1, HSD17B2, IDO1, NQO2, PTGS1, PTGS2, TBXAS1, TYR, XDH |
8.3228 |
|
[MF] GO:0016829 |
lyase activity
|
APEX1, CA1, CA12, CA14, CA2, CA3, CA4, CA5A, CA5B, CA6, CA7, CA9, GLO1, POLB |
8.18424 |
|
[MF] GO:0098531 |
transcription factor activity, direct ligand regulated sequence-specific DNA binding
|
AR, ESR1, ESR2, ESRRA, ESRRB, GPER1, PGR, PPARA, RORC |
8.09602 |
|
[MF] GO:0004879 |
nuclear receptor activity
|
AR, ESR1, ESR2, ESRRA, ESRRB, GPER1, PGR, PPARA, RORC |
8.09602 |
|
[MF] GO:0070405 |
ammonium ion binding
|
ACHE, DRD1, DRD2, DRD3, DRD5, HTR1A, HTR2A, HTR2B, HTR5A, HTR7 |
7.93162 |
|
[MF] GO:0020037 |
heme binding
|
CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, CYP2D6, IDO1, PTGS1, PTGS2, SRC, TBXAS1 |
7.89783 |
|
[MF] GO:0048037 |
cofactor binding
|
ALDH2, AOX1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, CYP2D6, DAO, HSD11B2, HSD17B1, IDO1, NQO2, POLA1, PTGS1, PTGS2, SRC, TBXAS1, XDH |
7.78017 |
|
[MF] GO:0008227 |
None
|
ADRA1A, ADRB1, DRD2, HTR1A, HTR2A, HTR2B, HTR5A, HTR6, HTR7 |
7.60257 |
|
[MF] GO:0046906 |
tetrapyrrole binding
|
CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, CYP2D6, IDO1, PTGS1, PTGS2, SRC, TBXAS1 |
7.58086 |
|
[MF] GO:0042562 |
hormone binding
|
ACHE, AR, EGFR, GPER1, HSD17B1, IGF1R, INSR, NQO2, NR3C1, SHBG |
7.38143 |
|
[MF] GO:0016712 |
oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen
|
CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, CYP2D6 |
7.34267 |
|
[MF] GO:0004714 |
transmembrane receptor protein tyrosine kinase activity
|
AXL, EGFR, ERBB2, FLT3, IGF1R, INSR, KDR, MET, TEK |
7.32921 |
|
[MF] GO:0004672 |
protein kinase activity
|
AURKB, AXL, CDK6, CSNK2A1, DYRK1A, EGFR, ERBB2, FLT3, IGF1R, INSR, KDR, MET, NUAK1, PIK3CA, PIM1, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, SRC, TEK |
7.17763 |
|
[MF] GO:0016773 |
phosphotransferase activity, alcohol group as acceptor
|
AURKB, AXL, CDK6, CSNK2A1, DYRK1A, EGFR, ERBB2, FLT3, IGF1R, INSR, KDR, MET, NUAK1, PIK3CA, PIK3CB, PIM1, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, SRC, TEK |
6.47378 |
|
[MF] GO:0019199 |
transmembrane receptor protein kinase activity
|
AXL, EGFR, ERBB2, FLT3, IGF1R, INSR, KDR, MET, TEK |
6.4442 |
|
[MF] GO:0030594 |
None
|
DRD1, DRD2, DRD3, DRD5, HTR1A, HTR2A, HTR2B, HTR5A, HTR6, HTR7 |
6.40411 |
|
[MF] GO:0016772 |
transferase activity, transferring phosphorus-containing groups
|
AURKB, AXL, CDK6, CSNK2A1, DYRK1A, EGFR, ERBB2, FLT3, IGF1R, INSR, KDR, MET, NUAK1, PIK3CA, PIK3CB, PIM1, POLA1, POLB, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, SRC, TEK, TERT |
6.37621 |
|
[MF] GO:0004713 |
protein tyrosine kinase activity
|
AXL, DYRK1A, EGFR, ERBB2, FLT3, IGF1R, INSR, KDR, MET, PRKCD, SRC, TEK |
6.37136 |
|
[MF] GO:0099600 |
transmembrane receptor activity
|
ADORA1, ADORA3, ADRA1A, ADRB1, AXL, DRD1, DRD2, DRD3, DRD5, EGFR, ERBB2, F3, FLT3, GPER1, GPR35, HCAR2, HTR1A, HTR2A, HTR2B, HTR5A, HTR6, HTR7, IGF1R, INSR, KDR, MET, SIGMAR1, TEK, TRPV1 |
6.33011 |
|
[MF] GO:0004888 |
transmembrane signaling receptor activity
|
ADORA1, ADORA3, ADRA1A, ADRB1, AXL, DRD1, DRD2, DRD3, DRD5, EGFR, ERBB2, F3, FLT3, GPER1, GPR35, HCAR2, HTR1A, HTR2A, HTR2B, HTR5A, HTR6, HTR7, IGF1R, INSR, KDR, MET, SIGMAR1, TEK, TRPV1 |
6.33011 |
|
[MF] GO:0043176 |
None
|
HTR1A, HTR2A, HTR2B, HTR5A, HTR7 |
6.20412 |
|
[MF] GO:0051378 |
None
|
HTR1A, HTR2A, HTR2B, HTR5A, HTR7 |
6.20412 |
|
[MF] GO:0043560 |
insulin receptor substrate binding
|
IGF1R, INSR, PIK3CA, PIK3CB, PRKCD |
6.20412 |
|
[MF] GO:0070330 |
aromatase activity
|
CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2D6 |
6.08526 |
|
[MF] GO:0016705 |
oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen
|
CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, CYP2D6, PTGS1, PTGS2, TBXAS1, TYR |
6.05647 |
|
[MF] GO:0004993 |
None
|
HTR1A, HTR2A, HTR2B, HTR5A, HTR6, HTR7 |
5.98285 |
|
[MF] GO:0099589 |
None
|
HTR1A, HTR2A, HTR2B, HTR5A, HTR6, HTR7 |
5.98285 |
|
[MF] GO:1901363 |
heterocyclic compound binding
|
ABCB1, ABCG2, ADORA1, ALDH2, AOX1, APEX1, APP, AR, AURKB, AXL, BCL2, CDK6, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, CYP2D6, DAO, DNMT1, DYRK1A, EGFR, ERBB2, ESR1, ESR2, ESRRA, ESRRB, FLT3, HIF1A, HSD11B2, HSD17B1, HSPA1A, HTR1A, HTR2A, HTR2B, HTR5A, HTR7, IDO1, IGF1R, INSR, KDR, MET, MMP12, NQO2, NR3C1, NR3C2, NUAK1, PGR, PIK3CA, PIK3CB, PIM1, POLA1, POLB, PPARA, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, PTGS1, PTGS2, PTPN1, RORC, SMAD3, SRC, TBXAS1, TEK, TERT, TOP2A, TRPV1, XDH |
5.95725 |
|
[MF] GO:0005506 |
iron ion binding
|
ALOX5, AOX1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, CYP2D6, TBXAS1, XDH |
5.93587 |
|
[MF] GO:0016301 |
kinase activity
|
AURKB, AXL, CDK6, CSNK2A1, DYRK1A, EGFR, ERBB2, FLT3, IGF1R, INSR, KDR, MET, NUAK1, PIK3CA, PIK3CB, PIM1, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, SRC, TEK |
5.83343 |
|
[MF] GO:0004497 |
monooxygenase activity
|
CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, CYP2D6, TBXAS1, TYR |
5.80793 |
|
[MF] GO:0019899 |
enzyme binding
|
ADRB1, ALPI, APP, AR, AURKB, BACE1, BCL2, CDC25B, CYP1A1, CYP1A2, CYP2A6, DUSP3, EGFR, ERBB2, ESR1, ESR2, ESRRB, F3, HIF1A, HSPA1A, MET, MIF, NR3C1, PGR, POLA1, POLB, PPARA, PRKCA, PRKCB, PRKCD, PRKCE, PTGS2, PTPN1, SMAD3, SRC, TEK, TNKS2, TOP2A |
5.60076 |
|
[MF] GO:0000166 |
nucleotide binding
|
ABCB1, ABCG2, ALDH2, AOX1, AURKB, AXL, CDK6, CSNK2A1, DAO, DNMT1, DYRK1A, EGFR, ERBB2, FLT3, HSD11B2, HSD17B1, HSPA1A, IGF1R, INSR, KDR, MET, NQO2, NUAK1, PIK3CA, PIK3CB, PIM1, POLA1, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, SRC, TEK, TOP2A, TRPV1, XDH |
5.54725 |
|
[MF] GO:1901265 |
nucleoside phosphate binding
|
ABCB1, ABCG2, ALDH2, AOX1, AURKB, AXL, CDK6, CSNK2A1, DAO, DNMT1, DYRK1A, EGFR, ERBB2, FLT3, HSD11B2, HSD17B1, HSPA1A, IGF1R, INSR, KDR, MET, NQO2, NUAK1, PIK3CA, PIK3CB, PIM1, POLA1, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, SRC, TEK, TOP2A, TRPV1, XDH |
5.54359 |
|
[MF] GO:0004697 |
None
|
PRKCA, PRKCB, PRKCD, PRKCE, PRKCG |
5.33257 |
|
[MF] GO:0036094 |
small molecule binding
|
ABCB1, ABCG2, ADORA1, ALDH2, AOX1, AURKB, AXL, CDK6, CSNK2A1, DAO, DNMT1, DYRK1A, EGFR, ERBB2, FABP3, FABP4, FLT3, HSD11B2, HSD17B1, HSPA1A, IGF1R, INSR, KDR, MET, NQO2, NUAK1, PIK3CA, PIK3CB, PIM1, POLA1, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, SRC, TEK, TOP2A, TRPV1, XDH |
5.24592 |
|
[MF] GO:0008289 |
lipid binding
|
AR, AXL, ESR1, ESR2, ESRRA, ESRRB, F3, FABP3, FABP4, GPER1, HSD11B2, HSD17B1, NR3C1, NR3C2, PGR, PPARA, RORC, SHBG, TRPV1 |
4.92674 |
|
[MF] GO:1901338 |
None
|
ADRB1, DRD1, DRD2, DRD3, DRD5 |
4.84901 |
|
[MF] GO:0099528 |
None
|
HTR1A, HTR2A, HTR2B, HTR5A, HTR6, HTR7 |
4.82859 |
|
[MF] GO:0004716 |
signal transducer, downstream of receptor, with protein tyrosine kinase activity
|
EGFR, ERBB2, INSR, KDR |
4.74476 |
|
[MF] GO:0005524 |
ATP binding
|
ABCB1, ABCG2, AURKB, AXL, CDK6, CSNK2A1, DYRK1A, EGFR, ERBB2, FLT3, HSPA1A, IGF1R, INSR, KDR, MET, NUAK1, PIK3CA, PIK3CB, PIM1, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, SRC, TEK, TOP2A, TRPV1 |
4.45734 |
|
[MF] GO:0019825 |
oxygen binding
|
CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2D6 |
4.43357 |
|
[MF] GO:0009055 |
electron transfer activity
|
AKR1B1, ALDH2, AOX1, CYP19A1, CYP1A2, IDO1, NQO2, XDH |
4.34402 |
|
[MF] GO:0032559 |
adenyl ribonucleotide binding
|
ABCB1, ABCG2, AURKB, AXL, CDK6, CSNK2A1, DYRK1A, EGFR, ERBB2, FLT3, HSPA1A, IGF1R, INSR, KDR, MET, NUAK1, PIK3CA, PIK3CB, PIM1, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, SRC, TEK, TOP2A, TRPV1 |
4.27906 |
|
[MF] GO:0004952 |
None
|
DRD1, DRD2, DRD3, DRD5 |
4.22927 |
|
[MF] GO:0030554 |
adenyl nucleotide binding
|
ABCB1, ABCG2, AURKB, AXL, CDK6, CSNK2A1, DYRK1A, EGFR, ERBB2, FLT3, HSPA1A, IGF1R, INSR, KDR, MET, NUAK1, PIK3CA, PIK3CB, PIM1, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, SRC, TEK, TOP2A, TRPV1 |
4.22824 |
|
[MF] GO:0004698 |
None
|
PRKCA, PRKCB, PRKCG |
4.14857 |
|
[MF] GO:0042165 |
neurotransmitter binding
|
ACHE, HTR1A, HTR2A, HTR2B, HTR5A, HTR7 |
4.10035 |
|
[MF] GO:0035240 |
None
|
DRD1, DRD2, DRD3, DRD5 |
4.10035 |
|
[MF] GO:0003674 |
molecular_function
|
ABCB1, ABCG2, ACHE, ADORA1, ADORA3, ADRA1A, ADRB1, AKR1B1, AKR1B10, ALDH2, ALOX5, ALPI, ALPL, AOX1, APEX1, APP, AR, AURKB, AXL, BACE1, BCL2, CA1, CA12, CA14, CA2, CA3, CA4, CA5A, CA5B, CA6, CA7, CA9, CACNA1C, CDC25B, CDK6, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, CYP2D6, DAO, DNMT1, DRD1, DRD2, DRD3, DRD5, DUSP3, DYRK1A, EGFR, ERBB2, ESR1, ESR2, ESRRA, ESRRB, F3, FABP3, FABP4, FLT3, FUCA1, FUT7, GAA, GBA, GBA2, GLO1, GPER1, GPR35, HCAR2, HIF1A, HSD11B1, HSD11B2, HSD17B1, HSD17B2, HSPA1A, HTR1A, HTR2A, HTR2B, HTR5A, HTR6, HTR7, IDO1, IGF1R, INSR, KDR, MET, MGAM, MIF, MMP1, MMP12, MMP2, MMP9, NQO2, NR3C1, NR3C2, NUAK1, PGR, PIK3CA, PIK3CB, PIM1, POLA1, POLB, PPARA, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, PTGS1, PTGS2, PTPN1, RORC, SHBG, SIGMAR1, SLC22A1, SLC22A2, SLC22A3, SLC47A1, SLC47A2, SMAD3, SRC, TBXAS1, TEK, TERT, TNKS, TNKS2, TOP2A, TRPV1, TYR, XDH |
3.89649 |
|
[MF] GO:0030284 |
estrogen receptor activity
|
ESR1, ESR2, GPER1 |
3.79503 |
|
[MF] GO:0008395 |
steroid hydroxylase activity
|
CYP19A1, CYP1A1, CYP2A13, CYP2A6, CYP2D6 |
3.7776 |
|
[MF] GO:0015238 |
None
|
ABCB1, ABCG2, SLC22A1, SLC22A2, SLC22A3, SLC47A1, SLC47A2 |
3.73454 |
|
[MF] GO:0042802 |
identical protein binding
|
ABCG2, ACHE, AOX1, APP, BCL2, CSNK2A1, DRD2, DYRK1A, EGFR, ERBB2, ESR1, ESR2, FLT3, IGF1R, KDR, MET, MIF, MMP9, NQO2, PGR, PTGS2, SLC22A1, SMAD3, TERT, TOP2A, TRPV1, TYR, XDH |
3.71913 |
|
[MF] GO:0016614 |
oxidoreductase activity, acting on CH-OH group of donors
|
AKR1B1, AKR1B10, AOX1, HSD11B1, HSD11B2, HSD17B1, HSD17B2, XDH |
3.67908 |
|
[MF] GO:0005329 |
None
|
SLC22A1, SLC22A2, SLC22A3 |
3.5288 |
|
[MF] GO:0016903 |
None
|
AKR1B1, AKR1B10, ALDH2, AOX1, XDH |
3.26699 |
|
[MF] GO:0046983 |
protein dimerization activity
|
ABCG2, ACHE, ADORA1, ADRA1A, ADRB1, AOX1, AR, AXL, BCL2, DAO, DRD2, EGFR, ERBB2, FLT3, HIF1A, NQO2, PTGS2, SLC22A1, SMAD3, TERT, TOP2A, TYR, XDH |
3.25104 |
|
[MF] GO:0004674 |
protein serine/threonine kinase activity
|
AURKB, CDK6, CSNK2A1, DYRK1A, EGFR, NUAK1, PIK3CA, PIM1, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG |
3.23127 |
|
[MF] GO:0043168 |
anion binding
|
ABCB1, ABCG2, AOX1, APP, AURKB, AXL, CDK6, CSNK2A1, DAO, DYRK1A, EGFR, ERBB2, F3, FABP3, FABP4, FLT3, HSD17B1, HSPA1A, IGF1R, INSR, KDR, MET, NQO2, NUAK1, PIK3CA, PIK3CB, PIM1, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, SRC, TEK, TOP2A, TRPV1, XDH |
3.02627 |
|
[MF] GO:0008504 |
None
|
SLC22A1, SLC22A2, SLC22A3 |
2.99089 |
|
[MF] GO:0015651 |
None
|
SLC22A1, SLC22A2, SLC22A3 |
2.99089 |
|
[MF] GO:0004930 |
None
|
ADORA1, ADORA3, ADRA1A, ADRB1, DRD1, DRD2, DRD3, DRD5, GPER1, GPR35, HCAR2, HTR1A, HTR2A, HTR2B, HTR5A, HTR6, HTR7, SIGMAR1 |
2.98978 |
|
[MF] GO:0035639 |
purine ribonucleoside triphosphate binding
|
ABCB1, ABCG2, AURKB, AXL, CDK6, CSNK2A1, DYRK1A, EGFR, ERBB2, FLT3, HSPA1A, IGF1R, INSR, KDR, MET, NUAK1, PIK3CA, PIK3CB, PIM1, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, SRC, TEK, TOP2A, TRPV1 |
2.93343 |
|
[MF] GO:0033764 |
steroid dehydrogenase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
|
HSD11B1, HSD11B2, HSD17B1, HSD17B2 |
2.90838 |
|
[MF] GO:0005488 |
binding
|
ABCB1, ABCG2, ACHE, ADORA1, ADRA1A, ADRB1, AKR1B10, ALDH2, ALOX5, ALPI, ALPL, AOX1, APEX1, APP, AR, AURKB, AXL, BACE1, BCL2, CA1, CA12, CA14, CA2, CA3, CA4, CA5A, CA5B, CA6, CA7, CA9, CACNA1C, CDC25B, CDK6, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, CYP2D6, DAO, DNMT1, DRD1, DRD2, DRD3, DRD5, DUSP3, DYRK1A, EGFR, ERBB2, ESR1, ESR2, ESRRA, ESRRB, F3, FABP3, FABP4, FLT3, GAA, GBA, GLO1, GPER1, HIF1A, HSD11B2, HSD17B1, HSPA1A, HTR1A, HTR2A, HTR2B, HTR5A, HTR6, HTR7, IDO1, IGF1R, INSR, KDR, MET, MGAM, MIF, MMP1, MMP12, MMP2, MMP9, NQO2, NR3C1, NR3C2, NUAK1, PGR, PIK3CA, PIK3CB, PIM1, POLA1, POLB, PPARA, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, PTGS1, PTGS2, PTPN1, RORC, SHBG, SIGMAR1, SLC22A1, SLC22A3, SMAD3, SRC, TBXAS1, TEK, TERT, TNKS, TNKS2, TOP2A, TRPV1, TYR, XDH |
2.8022 |
|
[MF] GO:0016229 |
steroid dehydrogenase activity
|
HSD11B1, HSD11B2, HSD17B1, HSD17B2 |
2.8022 |
|
[MF] GO:0004666 |
prostaglandin-endoperoxide synthase activity
|
PTGS1, PTGS2 |
2.77861 |
|
[MF] GO:0038052 |
RNA polymerase II transcription factor activity, estrogen-activated sequence-specific DNA binding
|
ESR1, ESR2 |
2.77861 |
|
[MF] GO:0003845 |
None
|
HSD11B1, HSD11B2 |
2.77861 |
|
[MF] GO:0008389 |
None
|
CYP2A13, CYP2A6 |
2.77861 |
|
[MF] GO:0035403 |
None
|
PRKCA, PRKCB |
2.77861 |
|
[MF] GO:0009931 |
None
|
PRKCA, PRKCB, PRKCG |
2.75661 |
|
[MF] GO:0051879 |
Hsp90 protein binding
|
CSNK2A1, HIF1A, KDR, NR3C1 |
2.65922 |
|
[MF] GO:0010857 |
None
|
PRKCA, PRKCB, PRKCG |
2.65222 |
|
[MF] GO:0097367 |
carbohydrate derivative binding
|
ABCB1, ABCG2, ADORA1, APP, AURKB, AXL, CDK6, CSNK2A1, DYRK1A, EGFR, ERBB2, FLT3, HSPA1A, IGF1R, INSR, KDR, MET, NUAK1, PIK3CA, PIK3CB, PIM1, POLA1, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, SRC, TEK, TOP2A, TRPV1 |
2.6447 |
|
[MF] GO:0032555 |
purine ribonucleotide binding
|
ABCB1, ABCG2, AURKB, AXL, CDK6, CSNK2A1, DYRK1A, EGFR, ERBB2, FLT3, HSPA1A, IGF1R, INSR, KDR, MET, NUAK1, PIK3CA, PIK3CB, PIM1, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, SRC, TEK, TOP2A, TRPV1 |
2.64007 |
|
[MF] GO:0017076 |
purine nucleotide binding
|
ABCB1, ABCG2, AURKB, AXL, CDK6, CSNK2A1, DYRK1A, EGFR, ERBB2, FLT3, HSPA1A, IGF1R, INSR, KDR, MET, NUAK1, PIK3CA, PIK3CB, PIM1, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, SRC, TEK, TOP2A, TRPV1 |
2.62344 |
|
[MF] GO:0032553 |
ribonucleotide binding
|
ABCB1, ABCG2, AURKB, AXL, CDK6, CSNK2A1, DYRK1A, EGFR, ERBB2, FLT3, HSPA1A, IGF1R, INSR, KDR, MET, NUAK1, PIK3CA, PIK3CB, PIM1, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, SRC, TEK, TOP2A, TRPV1 |
2.61958 |
|
[MF] GO:0031072 |
heat shock protein binding
|
ADORA1, CSNK2A1, HIF1A, HSPA1A, KDR, NR3C1 |
2.56862 |
|
[MF] GO:0046934 |
phosphatidylinositol-4,5-bisphosphate 3-kinase activity
|
EGFR, ERBB2, MET, PIK3CA, PIK3CB |
2.55022 |
|
[MF] GO:0032403 |
protein complex binding
|
ACHE, ADORA1, APEX1, EGFR, ESRRB, FLT3, HTR2A, IGF1R, INSR, KDR, MMP12, MMP9, PPARA, PTPN1, SMAD3, SRC |
2.49727 |
|
[MF] GO:0015926 |
None
|
GAA, GBA2, MGAM |
2.46925 |
|
[MF] GO:0052813 |
phosphatidylinositol bisphosphate kinase activity
|
EGFR, ERBB2, MET, PIK3CA, PIK3CB |
2.46881 |
|
[MF] GO:0005102 |
receptor binding
|
ADORA1, ADRB1, APP, AR, DAO, DRD2, DRD3, EGFR, ERBB2, ESR1, ESR2, FLT3, GBA, HIF1A, HSPA1A, HTR1A, IGF1R, INSR, KDR, MIF, PRKCB, PTPN1, SMAD3, SRC |
2.40495 |
|
[MF] GO:0044877 |
macromolecular complex binding
|
ACHE, ADORA1, APEX1, CSNK2A1, EGFR, ESRRB, FLT3, HTR2A, IGF1R, INSR, KDR, MMP12, MMP9, PIM1, PPARA, PTPN1, SMAD3, SRC |
2.39995 |
|
[MF] GO:0019902 |
phosphatase binding
|
BCL2, EGFR, ERBB2, MET, PPARA, PTPN1, SMAD3 |
2.39187 |
|
[MF] GO:1901375 |
None
|
SLC22A1, SLC22A2 |
2.38176 |
|
[MF] GO:0015307 |
None
|
SLC47A1, SLC47A2 |
2.38176 |
|
[MF] GO:0005333 |
None
|
SLC22A1, SLC22A2 |
2.38176 |
|
[MF] GO:0032450 |
None
|
GAA, MGAM |
2.38176 |
|
[MF] GO:0005277 |
None
|
SLC22A1, SLC22A2 |
2.38176 |
|
[MF] GO:0008513 |
None
|
SLC22A1, SLC22A2 |
2.38176 |
|
[MF] GO:0004699 |
None
|
PRKCD, PRKCE |
2.38176 |
|
[MF] GO:0004348 |
None
|
GBA, GBA2 |
2.38176 |
|
[MF] GO:0046982 |
protein heterodimerization activity
|
ADORA1, ADRA1A, ADRB1, AXL, BCL2, DRD2, EGFR, ERBB2, HIF1A, SMAD3, TOP2A, TYR |
2.35566 |
|
[MF] GO:0035004 |
phosphatidylinositol 3-kinase activity
|
EGFR, ERBB2, MET, PIK3CA, PIK3CB |
2.35399 |
|
[MF] GO:0019901 |
None
|
CDC25B, DUSP3, EGFR, ESR1, HIF1A, NR3C1, POLA1, PRKCB, PRKCD, PTPN1, SMAD3, SRC, TOP2A |
2.33264 |
|
[MF] GO:0019900 |
None
|
AURKB, CDC25B, DUSP3, EGFR, ESR1, HIF1A, NR3C1, POLA1, PRKCB, PRKCD, PTPN1, SMAD3, SRC, TOP2A |
2.32764 |
|
[MF] GO:0004935 |
None
|
ADRA1A, ADRB1, DRD2 |
2.32764 |
|
[MF] GO:0016616 |
oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
|
AKR1B1, AKR1B10, HSD11B1, HSD11B2, HSD17B1, HSD17B2 |
2.32596 |
|
[MF] GO:0005057 |
signal transducer activity, downstream of receptor
|
ADRB1, EGFR, ERBB2, INSR, KDR, SMAD3 |
2.27327 |
|
[MF] GO:0008134 |
transcription factor binding
|
APEX1, AR, BCL2, ESR1, ESRRB, FLT3, HIF1A, PIM1, PPARA, PRKCB, SMAD3, SRC, TERT |
2.26109 |
|
[MF] GO:0035173 |
histone kinase activity
|
AURKB, PRKCA, PRKCB |
2.25589 |
|
[MF] GO:0140096 |
catalytic activity, acting on a protein
|
AURKB, AXL, BACE1, CDC25B, CDK6, CSNK2A1, DUSP3, DYRK1A, EGFR, ERBB2, F3, FLT3, IGF1R, INSR, KDR, MET, MMP1, MMP12, MMP2, MMP9, NUAK1, PIK3CA, PIM1, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, PTPN1, SRC, TEK |
2.16648 |
|
[MF] GO:0016798 |
None
|
APEX1, FUCA1, GAA, GBA, GBA2, MGAM |
2.14436 |
|
[MF] GO:0019838 |
growth factor binding
|
EGFR, ERBB2, IGF1R, INSR, KDR, TEK |
2.14436 |
|
[MF] GO:0001588 |
None
|
DRD1, DRD5 |
2.1347 |
|
[MF] GO:0034056 |
estrogen response element binding
|
ESR1, ESR2 |
2.1347 |
|
[MF] GO:0005497 |
None
|
AR, SHBG |
2.1347 |
|
[MF] GO:0051425 |
None
|
APP, INSR |
2.1347 |
|
[MF] GO:0004558 |
None
|
GAA, MGAM |
2.1347 |
|
[MF] GO:0001223 |
transcription coactivator binding
|
ESR1, PPARA, TERT |
2.07259 |
|
[MF] GO:0035258 |
None
|
ESR1, FLT3, PRKCB, SMAD3, SRC |
2.05813 |
|
[MF] GO:0000978 |
None
|
AR, ESR1, ESR2, ESRRA, HIF1A, NR3C1, PGR, PPARA, RORC, SMAD3 |
2.027 |
