Description of the Component
Component ID |
TCMH1680 |
Latin Name |
Sinomenium acutum |
English Name |
Orientvine |
Chinese Pinyin Name |
Qing Feng Teng |
中文名 |
青风藤 |
TCM Properties |
|
TCM Meridians |
|
Therapeutic Class English |
|
Therapeutic Class Chinese |
|
Functions |
|
Toxicity |
NA |
Geo-authentic habitats (道地产区) |
NA |
Reference |
Chinese Pharmacopoeia (2015) |
Barcode ID |
ITSAJ4218-14 |
Barcode Source |
BOLDSYSTEMS |
TCM Prescriptions with the Component
| Prescription ID | Prescription English Name | Prescription Chinese Name |
|---|---|---|
| TCMF3493 | Bao Gu Huo Luo Pills | 豹骨活络丸 |
| TCMF3516 | Bao Gu Zhui Feng Ointment | 豹骨追风膏 |
| TCMF3424 | Feng Shi Han Tong Tablets | 风湿寒痛片 |
| TCMF3440 | Feng Shi Ling Xian Oral Liquid | 风湿灵仙液 |
| TCMF3487 | Feng Shi Sheng Yao Capsules | 风湿圣药胶囊 |
| TCMFx3556 | Feng Shi Zhi Tong Yao Wine | 风湿止痛药酒 |
| TCMF1450 | Goupi Plaster | 狗皮膏 |
| TCMF2631 | Goupi Plaster, Dog-skin Plaster | 狗皮膏 |
| TCMFx4209 | Han Bi Ting Tablets | 寒痹停片 |
| TCMFx7075 | Hei Gu Teng Zhui Feng Huo Luo Capsules | 黑骨藤追风活络胶囊 |
| TCMFx4688 | Hu Gu Mu Gua Pills | 虎骨木瓜丸 |
| TCMF4819 | Jin Bu Huan Ointment | 金不换膏 |
| TCMF4284 | Jin Gu Ning Cha Ji | 筋骨宁搽剂 |
| TCMF2606 | Qufeng Shujin Pills | 祛风舒筋丸 |
| TCMF1431 | Qufeng Shujin Pills | 祛风舒筋丸 |
| TCMF3605 | Shen Rong Mu Gua Yao Wine | 参茸木瓜药酒 |
| TCMF5478 | Shu Luo Yang Gan Pills | 舒络养肝丸 |
| TCMFx5342 | Te Zhi Gou Pi Ointment | 特制狗皮膏 |
| TCMFx5163 | Tou Gu Zhen Feng Pills | 透骨镇风丸 |
| TCMF5461 | Wu Jia Pi Wine | 五加皮酒 |
| TCMFx6345 | Zheng Qing Feng Tong Ning Tablets | 正清风痛宁片 |
| TCMF6686 | Zhui Feng Zhuang Gu Ointment | 追风壮骨膏 |
Targeted Human Proteins by the Ingredient of Component
| Target ID | Gene Symbol | Target Name | Target Class | Uniprot ID |
|---|---|---|---|---|
| TCMT1 | EHMT2 | Histone-lysine N-methyltransferase, H3 lysine-9 specific 3 | Transferase | Q96KQ7 |
| TCMT101 | PTPN1 | Protein-tyrosine phosphatase 1B | Hydrolase | P18031 |
| TCMT112 | ADORA3 | Adenosine A3 receptor | GPCR | P0DMS8 |
| TCMT116 | OPRM1 | Mu opioid receptor | GPCR | P35372 |
| TCMT130 | ALOX5 | Arachidonate 5-lipoxygenase | Oxidoreductase | P09917 |
| TCMT131 | ACHE | Acetylcholinesterase | Hydrolase | P22303 |
| TCMT132 | BCHE | Butyrylcholinesterase | Hydrolase | P06276 |
| TCMT151 | PRKCA | Protein kinase C alpha | Kinase | P17252 |
| TCMT159 | TYR | Tyrosinase | Oxidoreductase | P14679 |
| TCMT17 | POLB | DNA polymerase beta | Transferase | P06746 |
| TCMT18 | GAA | Lysosomal alpha-glucosidase | Hydrolase | P10253 |
| TCMT186 | MAOB | Monoamine oxidase B | Oxidoreductase | P27338 |
| TCMT195 | MAP2K1 | Dual specificity mitogen-activated protein kinase kinase 1 | Kinase | Q02750 |
| TCMT2 | MAPT | Microtubule-associated protein tau | Unclassified | P10636 |
| TCMT213 | SLC22A1 | Solute carrier family 22 member 1 | Transporter | O15245 |
| TCMT217 | CYP2C8 | Cytochrome P450 2C8 | Oxidoreductase | P10632 |
| TCMT218 | CYP2B6 | Cytochrome P450 2B6 | Oxidoreductase | P20813 |
| TCMT219 | CYP1A2 | Cytochrome P450 1A2 | Oxidoreductase | P05177 |
| TCMT265 | GSK3B | Glycogen synthase kinase-3 beta | Kinase | P49841 |
| TCMT27 | DRD1 | Dopamine D1 receptor | GPCR | P21728 |
| TCMT276 | SLCO2B1 | Solute carrier organic anion transporter family member 2B1 | Transporter | O94956 |
| TCMT277 | SLCO1B3 | Solute carrier organic anion transporter family member 1B3 | Transporter | Q9NPD5 |
| TCMT278 | SLCO1B1 | Solute carrier organic anion transporter family member 1B1 | Transporter | Q9Y6L6 |
| TCMT281 | DPP4 | Dipeptidyl peptidase IV | Unclassified | P27487 |
| TCMT295 | MMP1 | Matrix metalloproteinase-1 | Hydrolase | P03956 |
| TCMT296 | ADORA1 | Adenosine A1 receptor | GPCR | P30542 |
| TCMT306 | MMP2 | Matrix metalloproteinase-2 | Hydrolase | P08253 |
| TCMT307 | KCNH2 | HERG | Ion channel | Q12809 |
| TCMT31 | CYP2C19 | Cytochrome P450 2C19 | Oxidoreductase | P33261 |
| TCMT320 | MMP3 | Matrix metalloproteinase 3 | Hydrolase | P08254 |
| TCMT321 | MMP9 | Matrix metalloproteinase 9 | Hydrolase | P14780 |
| TCMT33 | CYP3A4 | Cytochrome P450 3A4 | Oxidoreductase | P08684 |
| TCMT34 | CYP2D6 | Cytochrome P450 2D6 | Oxidoreductase | P10635 |
| TCMT36 | HTR1A | Serotonin 1a (5-HT1a) receptor | GPCR | P08908 |
| TCMT37 | HTR2A | Serotonin 2a (5-HT2a) receptor | GPCR | P28223 |
| TCMT38 | DRD2 | Dopamine D2 receptor | GPCR | P14416 |
| TCMT41 | IDH1 | Isocitrate dehydrogenase [NADP] cytoplasmic | Oxidoreductase | O75874 |
| TCMT42 | KMT2A | Histone-lysine N-methyltransferase MLL | Transferase | Q03164 |
| TCMT46 | F3 | Coagulation factor III | Unclassified | P13726 |
| TCMT466 | MAPK9 | c-Jun N-terminal kinase 2 | Kinase | P45984 |
| TCMT479 | AKT1 | Serine/threonine-protein kinase AKT | Kinase | P31749 |
| TCMT507 | MAPK14 | MAP kinase p38 alpha | Kinase | Q16539 |
| TCMT559 | ADRB2 | Beta-2 adrenergic receptor | GPCR | P07550 |
| TCMT571 | ADORA2B | Adenosine A2b receptor | GPCR | P29275 |
| TCMT592 | XDH | Xanthine dehydrogenase | Oxidoreductase | P47989 |
| TCMT598 | TOP1 | DNA topoisomerase I | Isomerase | P11387 |
| TCMT624 | HSP90AB1 | Heat shock protein HSP 90-beta | Unclassified | P08238 |
| TCMT64 | PPARD | Peroxisome proliferator-activated receptor delta | Nuclear receptor | Q03181 |
| TCMT648 | DRD4 | Dopamine D4 receptor | GPCR | P21917 |
| TCMT649 | DRD5 | Dopamine D5 receptor | GPCR | P21918 |
| TCMT651 | DRD3 | Dopamine D3 receptor | GPCR | P35462 |
| TCMT707 | ADORA2A | Adenosine A2a receptor | GPCR | P29274 |
| TCMT729 | PIK3CA | PI3-kinase p110-alpha subunit | Transferase | P42336 |
| TCMT730 | PIK3CB | PI3-kinase p110-beta subunit | Transferase | P42338 |
| TCMT740 | PIK3CG | PI3-kinase p110-gamma subunit | Transferase | P48736 |
| TCMT8 | KDM4E | Lysine-specific demethylase 4D-like | Oxidoreductase | B2RXH2 |
| TCMT80 | MAPK1 | MAP kinase ERK2 | Kinase | P28482 |
| TCMT87 | CYP2C9 | Cytochrome P450 2C9 | Oxidoreductase | P11712 |
Targeted Pathogenic Microbes by the Ingredient of Component
| Target ID | Target Name |
|---|---|
| TCMT1218 | Staphylococcus aureus |
| TCMT1438 | Plasmodium falciparum |
| TCMT1463 | Mycobacterium tuberculosis |
| TCMT1465 | Entamoeba histolytica |
Ingredient Structrues
Ingredient ID: TCMC850
Formula: C8H10N4O2
Ingredient ID: TCMC801
Formula: C29H50O
Ingredient ID: TCMC722
Formula: C17H11NO7
Ingredient ID: TCMC6621
Formula: C38H44N2O8
Ingredient ID: TCMC631
Formula: C5H5N5
Ingredient ID: TCMC6303
Formula: C19H23NO4
Ingredient ID: TCMC5380
Formula: C17H15NO3
Ingredient ID: TCMC5335
Formula: C19H24ClNO6
Ingredient ID: TCMC5210
Formula: C20H21NO4
Ingredient ID: TCMC4324
Formula: C29H48O
Ingredient ID: TCMC4166
Formula: C19H23NO4
Ingredient ID: TCMC3966
Formula: C29H50O
Ingredient ID: TCMC3927
Formula: C18H22ClNO6
Ingredient ID: TCMC3784
Formula: C18H19NO3
Ingredient ID: TCMC3717
Formula: C18H19NO3
Ingredient ID: TCMC315
Formula: C21H25NO4
Ingredient ID: TCMC2964
Formula: C17H34O2
Ingredient ID: TCMC2676
Formula: C19H23NO4
Ingredient ID: TCMC2516
Formula: C38H42N2O6
Ingredient ID: TCMC2487
Formula: C15H22O2
Ingredient ID: TCMC2383
Formula: C20H23NO4
Ingredient ID: TCMC2117
Formula: C22H26O8
Ingredient ID: TCMC2106
Formula: C19H21NO4
Ingredient ID: TCMC2040
Formula: C19H21NO4
Ingredient ID: TCMC1841
Formula: C7H8N4O2
Ingredient ID: TCMC1767
Formula: C18H19NO4
Ingredient ID: TCMC1652
Formula: C36H38N2O6
Ingredient ID: TCMC1625
Formula: C20H21NO4
Ingredient ID: TCMC1457
Formula: C3H6O3
Ingredient ID: TCMC1171
Formula: C37H40N2O6
Ingredient ID: TCMC1170
Formula: C38H42N2O6
Properties
| Ingredient ID | Formulae | Name | MW | AlogP | MlogP | XlogP | # HBA | # HBD | PSA | # Rotatable Bond | # Ring | # Heacy Atom | Lipinski RO5 Violation |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| TCMC315 | C21H25NO4 | 2,3,9,10-Tetramethoxy-6,8,13,13A-Tetrahydro-5H-Isoquinolino[2,1-B]Isoquinoline | 355.18 | 0.0968 | 3.22 | 2.548 | 1 | 0 | 40.16 | 8 | 4 | 26 | 0 |
| TCMC631 | C5H5N5 | Adenine | 135.05 | -1.1703 | 1.46 | -0.664 | 5 | 2 | 80.48 | 1 | 2 | 10 | 0 |
| TCMC722 | C17H11NO7 | Aristolochic Acid | 341.05 | 0.0658 | 2.45 | 2.79 | 2 | 1 | 108.13 | 6 | 4 | 25 | 0 |
| TCMC801 | C29H50O | Beta-Sitosterol | 414.39 | 1.3 | 4.54 | 11.595 | 1 | 1 | 20.23 | 13 | 4 | 30 | 1 |
| TCMC850 | C8H10N4O2 | Caffeine | 194.08 | -0.4311 | 1.68 | -0.625 | 6 | 0 | 58.44 | 3 | 2 | 14 | 0 |
| TCMC1170 | C38H42N2O6 | Fanchinin | 622.3 | 0.274 | 4.76 | 6.098 | 2 | 0 | 61.86 | 10 | 6 | 46 | 1 |
| TCMC1171 | C37H40N2O6 | Fangchinoline | 608.29 | -0.1345 | 4.65 | 5.579 | 2 | 1 | 72.86 | 9 | 6 | 45 | 1 |
| TCMC1457 | C3H6O3 | Lactic Acid | 90.03 | -0.8059 | 1.46 | -0.591 | 3 | 2 | 57.53 | 4 | 0 | 6 | 0 |
| TCMC1625 | C20H21NO4 | 339.15 | -0.0116 | 3.11 | 2.164 | 1 | 0 | 40.16 | 5 | 5 | 25 | 0 | |
| TCMC1652 | C36H38N2O6 | 594.27 | -0.543 | 4.54 | 5.06 | 2 | 2 | 83.86 | 8 | 6 | 44 | 1 | |
| TCMC1767 | C18H19NO4 | N-Trans-Feruloyl Tyramine | 313.13 | -0.6499 | 2.89 | 3.109 | 2 | 3 | 82.28 | 10 | 2 | 23 | 0 |
| TCMC1841 | C7H8N4O2 | Paraxanthine | 180.06 | 0.0198 | 1.57 | -0.503 | 6 | 1 | 70.72 | 3 | 2 | 13 | 0 |
| TCMC2040 | C19H21NO4 | Salutaridine | 327.15 | -0.6163 | 3 | 1.283 | 3 | 1 | 59 | 6 | 4 | 24 | 0 |
| TCMC2106 | C19H21NO4 | Stepholidine | 327.15 | -0.7202 | 3 | 1.51 | 1 | 2 | 62.16 | 6 | 4 | 24 | 0 |
| TCMC2117 | C22H26O8 | Syringaresinol | 418.16 | -2.1258 | 3 | 0.796 | 2 | 2 | 95.84 | 12 | 4 | 30 | 0 |
| TCMC2383 | C20H23NO4 | Magnoflorine | 342.17 | -1.9843 | 3.11 | 1.008 | 0 | 2 | 58.92 | 8 | 4 | 25 | 0 |
| TCMC2487 | C15H22O2 | Ligucyperonol | 234.16 | 1.7381 | 2.89 | 1.764 | 2 | 1 | 37.3 | 5 | 2 | 17 | 0 |
| TCMC2516 | C38H42N2O6 | Phaeanthine | 622.3 | 0.274 | 4.76 | 6.098 | 2 | 0 | 61.86 | 10 | 6 | 46 | 1 |
| TCMC2676 | C19H23NO4 | Sinomenine | 329.16 | -0.7813 | 3 | 1.294 | 3 | 1 | 59 | 6 | 4 | 24 | 0 |
| TCMC2964 | C17H34O2 | Methyl Hexadecanate,Methyl Palmitate | 270.2558803 | -3.6467 | 3.11 | 7.891 | 2 | 0 | 26.3 | 15 | 0 | 19 | 2 |
| TCMC3717 | C18H19NO3 | Stepharine | 298.1443185 | -1.1797 | 3 | 1.535 | 1 | 1 | 52.14 | 2 | 4 | 22 | 0 |
| TCMC3784 | C18H19NO3 | Tuduranine | 298.1443185 | -1.7286 | 3 | 2.035 | 0 | 2 | 55.3 | 2 | 4 | 22 | 0 |
| TCMC3927 | C18H22ClNO6 | Acutumidine | 384.1213901 | -3.9758 | 2.56 | -0.041 | 6 | 2 | 92.19 | 1 | 4 | 26 | 0 |
| TCMC3966 | C29H50O | Sitosterol,Β-Sitosterol | 414.3861662 | 1.3 | 4.54 | 11.595 | 1 | 1 | 20.23 | 6 | 4 | 30 | 1 |
| TCMC4166 | C19H23NO4 | Sinomenine | 330.1705332 | -2.2384 | 3 | 1.135 | 2 | 2 | 60.2 | 2 | 4 | 24 | 0 |
| TCMC4324 | C29H48O | Stigmasterol | 412.3705162 | 1.2566 | 4.54 | 11.071 | 1 | 1 | 20.23 | 5 | 4 | 30 | 1 |
| TCMC5210 | C20H21NO4 | Sinactine | 340.1548832 | -1.5594 | 3.11 | 2.316 | 0 | 1 | 41.36 | 2 | 5 | 25 | 0 |
| TCMC5335 | C19H24ClNO6 | Acutumine | 398.1370402 | -3.8735 | 2.67 | -0.073 | 6 | 2 | 80.02 | 1 | 4 | 27 | 0 |
| TCMC5380 | C17H15NO3 | Michelalbine | 282.1130184 | -2.0405 | 2.89 | 2.528 | 1 | 2 | 55.3 | 0 | 5 | 21 | 0 |
| TCMC6303 | C19H23NO4 | Isosinomenine | 330.1705332 | -2.5102 | 3 | 0.941 | 2 | 2 | 60.2 | 2 | 4 | 24 | 0 |
| TCMC6621 | C38H44N2O8 | Disinomenine | 658.3254164 | -4.4768 | 4.54 | 1.438 | 4 | 4 | 120.4 | 5 | 8 | 48 | 0 |
Download Data
All data can be downloaded by:→ Selecting data type in the below download table
→ Then click the download button.
