Description of the Component
Component ID |
TCMH121 |
Latin Name |
Biota orientalis |
English Name |
Chinese arborvitae kernel |
Chinese Pinyin Name |
Bai Zi Ren |
中文名 |
柏子仁 |
TCM Properties |
Mild,Sweet |
TCM Meridians |
Large Intestine,Heart,Kidney |
Therapeutic Class English |
Spirit calming |
Therapeutic Class Chinese |
安神 |
Functions |
calm the nerves, check excessive perspiration, and relax the bowels |
Toxicity |
NA |
Geo-authentic habitats (道地产区) |
Shandong Province |
Reference |
Chinese Pharmacopoeia (2015) |
Barcode ID |
|
Barcode Source |
TCM Prescriptions with the Component
| Prescription ID | Prescription English Name | Prescription Chinese Name |
|---|---|---|
| TCMF1394 | Baizi Yangxin Pills | 柏子养心丸 |
| TCMF1422 | Tianwang Buxin Pills | 天王补心丸 |
| TCMF225 | Nü Zhen Granules | 女珍颗粒 |
| TCMF2300 | Brain Strengthening Decoction | 健脑安神 |
| TCMF2477 | Baizi Yangxin Pills | 柏子养心丸 |
| TCMF2485 | Heart Strengthening Decoction | 养心汤 |
| TCMF2509 | Liver and Mind Soothing Decoction | 疏肝养心汤 |
| TCMF2528 | Divine Ruler Heart Restoring Pills | 天王补心丹 |
| TCMF2589 | Tianwang Buxin Pills | 天王补心丸 |
| TCMF2603 | Spasm Relieving Decoction | 解痉汤 |
Showing 1 to 10 of 66 entries
Targeted Human Proteins by the Ingredient of Component
| Target ID | Gene Symbol | Target Name | Target Class | Uniprot ID |
|---|---|---|---|---|
| TCMT101 | PTPN1 | Protein-tyrosine phosphatase 1B | Hydrolase | P18031 |
| TCMT2 | MAPT | Microtubule-associated protein tau | Unclassified | P10636 |
| TCMT575 | PLA2G2A | Phospholipase A2 group IIA | Hydrolase | P14555 |
| TCMT61 | MCL1 | Induced myeloid leukemia cell differentiation protein Mcl-1 | Unclassified | Q07820 |
| TCMT666 | VCP | Transitional endoplasmic reticulum ATPase | Transporter | P55072 |
| TCMT69 | THRB | Thyroid hormone receptor beta-1 | Nuclear receptor | P10828 |
Showing 1 to 6 of 6 entries
Targeted Pathogenic Microbes by the Ingredient of Component
| Target ID | Target Name |
|---|---|
| TCMT1120 | Cell division protein ftsZ |
| TCMT1218 | Staphylococcus aureus |
| TCMT1438 | Plasmodium falciparum |
| TCMT1454 | Bacillus subtilis |
| TCMT1462 | Streptococcus mutans |
| TCMT1463 | Mycobacterium tuberculosis |
Showing 1 to 6 of 6 entries
Ingredient Structrues
Ingredient ID: TCMC680
Formula: C30H18O10
Ingredient ID: TCMC680
| Common Name | Amentoflavone |
| IUPAC Name | 8-[5-(5,7-dihydroxy-4-oxochromen-2-yl)-2-hydroxyphenyl]-5,7-dihydroxy-2-(4-hydroxyphenyl)chromen-4-one |
| Canonical SMILES | Oc1ccc(cc1)c1cc(=O)c2c(o1)c(c(cc2O)O)c1cc(ccc1O)c1cc(=O)c2c(o1)cc(cc2O)O |
| Standard InCHI | InChI=1S/C30H18O10/c31-15-4-1-13(2-5-15)24-12-23(38)29-21(36)10-20(35)27(30(29)40-24)17-7-14(3-6-18(17)33)25-11-22(37)28-19(34)8-16(32)9-26(28)39-25/h1-12,31-36H |
| Standard InCHIKey | YUSWMAULDXZHPY-UHFFFAOYSA-N |
| External Identifiers | ChEMBL [CHEMBL63354]; PubChem [5281600]; |
| Reference of Component-Ingredient Pair | 22837955 |
Occurrence of the ingredient across TCM components
| Component ID | Latin Name | Pinyin Name | Chinese Name |
|---|---|---|---|
| TCMH114 | Platycladus orientalis | Bai Ye | 柏叶 |
| TCMH1197 | Selaginella tamariscina | Juan Bai | 卷柏 |
| TCMH121 | Biota orientalis | Bai Zi Ren | 柏子仁 |
| TCMH1367 | Apocynum venetum | Luo Bu Ma | 罗布麻 |
| TCMH143 | Albizia julibrissin | Bei He Huan | 北合欢 |
| TCMH1649 | Toxicodendron succedaneum | Qi Shu Gen | 漆树根 |
| TCMH1950 | Herba selaginellae doederleinii | Shi Shang Bai | 石上柏 |
| TCMH223 | Platycladus orientalis | Ce Bai Tan | 侧柏炭 |
| TCMH224 | Thuja orientalis | Ce Bai Ye | 侧柏叶 |
| TCMH2267 | Periploca sepium | Xiang Jia Pi | 香加皮 |
Showing 1 to 10 of 14 entries
Ingredient ID: TCMC6496
Formula: C18H28O3
Ingredient ID: TCMC6496
| Common Name | 15,16-Bisnor-13-Oxo-8(17)-Labden-19-Oic Acid |
| IUPAC Name | (1S,4aR,5S,8aR)-1,4a-dimethyl-6-methylidene-5-(3-oxobutyl)-3,4,5,7,8,8a-hexahydro-2H-naphthalene-1-carboxylic acid |
| Canonical SMILES | CC(=O)CC[C@H]1C(=C)CC[C@@H]2[C@]1(C)CCC[C@]2(C)C(=O)[O-] |
| Standard InCHI | InChI=1S/C18H28O3/c1-12-6-9-15-17(3,14(12)8-7-13(2)19)10-5-11-18(15,4)16(20)21/h14-15H,1,5-11H2,2-4H3,(H,20,21)/p-1/t14-,15+,17+,18-/m0/s1 |
| Standard InCHIKey | WJXLWXJYJCBHME-IDCNUPLLSA-M |
| External Identifiers | ChEMBL [N/A]; PubChem [21635785]; |
| Reference of Component-Ingredient Pair | N/A |
Occurrence of the ingredient across TCM components
Ingredient ID: TCMC5316
Formula: C18H26O3
Ingredient ID: TCMC5316
| Common Name | 15,16-Bisnor-13-Oxo-8(17),11E-Labdadien-19-Oic Acid |
| IUPAC Name | (1S,4aS,5S,8aR)-1,4a-dimethyl-6-methylidene-5-[(E)-3-oxobut-1-enyl]-3,4,5,7,8,8a-hexahydro-2H-naphthalene-1-carboxylic acid |
| Canonical SMILES | CC(=O)/C=C/[C@H]1C(=C)CC[C@@H]2[C@]1(C)CCC[C@]2(C)C(=O)[O-] |
| Standard InCHI | InChI=1S/C18H26O3/c1-12-6-9-15-17(3,14(12)8-7-13(2)19)10-5-11-18(15,4)16(20)21/h7-8,14-15H,1,5-6,9-11H2,2-4H3,(H,20,21)/p-1/b8-7+/t14-,15+,17+,18-/m0/s1 |
| Standard InCHIKey | BQLIBSZGTNAGNT-OQOGXPRXSA-M |
| External Identifiers | ChEMBL [N/A]; PubChem [10085628]; |
| Reference of Component-Ingredient Pair | 18855216 |
Occurrence of the ingredient across TCM components
Ingredient ID: TCMC4090
Formula: C20H34O2
Ingredient ID: TCMC4090
| Common Name | Ent-Isopimara-15-En-Α,Α-Diol |
| IUPAC Name | (2R,4aR,4bS,7S,8aS,10aS)-7-ethenyl-1,1,4a,7-tetramethyl-2,3,4,4b,5,6,8,9,10,10a-decahydrophenanthrene-2,8a-diol |
| Canonical SMILES | C=C[C@@]1(C)CC[C@@H]2[C@](C1)(O)CC[C@H]1[C@@]2(C)CC[C@H](C1(C)C)O |
| Standard InCHI | InChI=1S/C20H34O2/c1-6-18(4)10-7-15-19(5)11-9-16(21)17(2,3)14(19)8-12-20(15,22)13-18/h6,14-16,21-22H,1,7-13H2,2-5H3/t14-,15+,16-,18+,19-,20+/m1/s1 |
| Standard InCHIKey | UIVFXGICZLHPQO-LZHQGQFHSA-N |
| External Identifiers | ChEMBL [N/A]; PubChem [637235]; |
| Reference of Component-Ingredient Pair | N/A |
Occurrence of the ingredient across TCM components
Ingredient ID: TCMC3966
Formula: C29H50O
Ingredient ID: TCMC3966
| Common Name | Sitosterol,Β-Sitosterol |
| IUPAC Name | (3S,8S,9S,10R,13R,14S,17R)-17-[(2R,5S)-5-ethyl-6-methylheptan-2-yl]-10,13-dimethyl-2,3,4,7,8,9,11,12,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-3-ol |
| Canonical SMILES | CC[C@H](C(C)C)CC[C@H]([C@H]1CC[C@@H]2[C@]1(C)CC[C@H]1[C@H]2CC=C2[C@]1(C)CC[C@@H](C2)O)C |
| Standard InCHI | InChI=1S/C29H50O/c1-7-21(19(2)3)9-8-20(4)25-12-13-26-24-11-10-22-18-23(30)14-16-28(22,5)27(24)15-17-29(25,26)6/h10,19-21,23-27,30H,7-9,11-18H2,1-6H3/t20-,21+,23+,24+,25-,26+,27+,28+,29-/m1/s1 |
| Standard InCHIKey | KZJWDPNRJALLNS-FBZNIEFRSA-N |
| External Identifiers | ChEMBL [CHEMBL221542]; PubChem [457801]; |
| Reference of Component-Ingredient Pair | 23115546 |
Occurrence of the ingredient across TCM components
| Component ID | Latin Name | Pinyin Name | Chinese Name |
|---|---|---|---|
| TCMH104 | Paeonia lactiflora | Bai Shao | 白芍 |
| TCMH1127 | Lonicera japonica | Jin Yin Hua | 金银花 |
| TCMH1186 | Lycium chinense | Gou Qi Zi | 枸杞子 |
| TCMH12 | Artemisia argyi | Ai Ye | 艾叶 |
| TCMH121 | Biota orientalis | Bai Zi Ren | 柏子仁 |
| TCMH127 | Isatis indigotica | Ban Lan Gen | 板蓝根 |
| TCMH130 | Pinellia ternata | Ban Xia | 半夏 |
| TCMH1359 | Pyrola calliantha | Lu Xian Cao | 鹿衔草 |
| TCMH1368 | Apocyni veneti folium | Luo Bu Ma Ye | 罗布麻叶 |
| TCMH1376 | Trachelospermum jasminoides | Luo Shi Teng | 络石藤 |
Showing 1 to 10 of 71 entries
Ingredient ID: TCMC3603
Formula: C21H30O4
Ingredient ID: TCMC3603
| Common Name | Pinusolide |
| IUPAC Name | methyl (1S,4aR,5S,8aR)-1,4a-dimethyl-6-methylidene-5-[2-(5-oxo-2H-furan-4-yl)ethyl]-3,4,5,7,8,8a-hexahydro-2H-naphthalene-1-carboxylate |
| Canonical SMILES | COC(=O)[C@@]1(C)CCC[C@]2([C@H]1CCC(=C)[C@@H]2CCC1=CCOC1=O)C |
| Standard InCHI | InChI=1S/C21H30O4/c1-14-6-9-17-20(2,11-5-12-21(17,3)19(23)24-4)16(14)8-7-15-10-13-25-18(15)22/h10,16-17H,1,5-9,11-13H2,2-4H3/t16-,17+,20+,21-/m0/s1 |
| Standard InCHIKey | WTKBZJAWPZXKJU-NLEAXPPASA-N |
| External Identifiers | ChEMBL [CHEMBL425068]; PubChem [161721]; |
| Reference of Component-Ingredient Pair | 23831466 |
Occurrence of the ingredient across TCM components
Ingredient ID: TCMC3208
Formula: C15H26O
Ingredient ID: TCMC3208
| Common Name | Cedrol,Eudesmol,Α-Cedrol |
| IUPAC Name | (1S,2R,5S,7R,8R)-2,6,6,8-tetramethyltricyclo[5.3.1.01,5]undecan-8-ol |
| Canonical SMILES | C[C@@H]1CC[C@@H]2[C@@]31CC[C@@]([C@H](C3)C2(C)C)(C)O |
| Standard InCHI | InChI=1S/C15H26O/c1-10-5-6-11-13(2,3)12-9-15(10,11)8-7-14(12,4)16/h10-12,16H,5-9H2,1-4H3/t10-,11+,12-,14-,15+/m1/s1 |
| Standard InCHIKey | SVURIXNDRWRAFU-OGMFBOKVSA-N |
| External Identifiers | ChEMBL [CHEMBL1974890]; PubChem [65575]; |
| Reference of Component-Ingredient Pair | 22818358 |
Occurrence of the ingredient across TCM components
| Component ID | Latin Name | Pinyin Name | Chinese Name |
|---|---|---|---|
| TCMH120 | Atractylodes macrocephala | Bai Zhu | 白术 |
| TCMH121 | Biota orientalis | Bai Zi Ren | 柏子仁 |
| TCMH144 | Herba artemisiae anomalae | Bei Liu Ji Nu | 北刘寄奴 |
| TCMH1533 | Saussurea lappa | Mu Xiang | 木香 |
| TCMH1721 | Panax ginseng | Ren Shen | 人参 |
| TCMH33 | Illicium verum | Ba Jiao Hui Xiang | 八角茴香 |
| TCMH797 | Sargassum | Hai Zao | 海藻 |
| TCMH877 | Radix ginseng rubra | Hong Shen | 红参 |
Showing 1 to 8 of 8 entries
Ingredient ID: TCMC2177
Formula: C20H30O
Ingredient ID: TCMC2177
| Common Name | Totarol |
| IUPAC Name | (4bS,8aS)-4b,8,8-trimethyl-1-propan-2-yl-5,6,7,8a,9,10-hexahydrophenanthren-2-ol |
| Canonical SMILES | CC(c1c(O)ccc2c1CC[C@@H]1[C@]2(C)CCCC1(C)C)C |
| Standard InCHI | InChI=1S/C20H30O/c1-13(2)18-14-7-10-17-19(3,4)11-6-12-20(17,5)15(14)8-9-16(18)21/h8-9,13,17,21H,6-7,10-12H2,1-5H3/t17-,20+/m0/s1 |
| Standard InCHIKey | ZRVDANDJSTYELM-FXAWDEMLSA-N |
| External Identifiers | ChEMBL [CHEMBL487602]; PubChem [92783]; |
| Reference of Component-Ingredient Pair | N/A |
Occurrence of the ingredient across TCM components
Properties
| Ingredient ID | Formulae | Name | MW | AlogP | MlogP | XlogP | # HBA | # HBD | PSA | # Rotatable Bond | # Ring | # Heacy Atom | Lipinski RO5 Violation |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| TCMC2177 | C20H30O | Totarol | 286.23 | 1.3229 | 3.55 | 8.211 | 0 | 1 | 20.23 | 7 | 3 | 21 | 1 |
| TCMC3208 | C15H26O | Cedrol,Eudesmol,Α-Cedrol | 222.1983655 | 1.3573 | 3 | 5.176 | 1 | 1 | 20.23 | 0 | 3 | 16 | 1 |
| TCMC3603 | C21H30O4 | Pinusolide | 346.2144094 | 1.4712 | 3.33 | 4.914 | 4 | 0 | 52.6 | 5 | 3 | 25 | 0 |
| TCMC3966 | C29H50O | Sitosterol,Β-Sitosterol | 414.3861662 | 1.3 | 4.54 | 11.595 | 1 | 1 | 20.23 | 6 | 4 | 30 | 1 |
| TCMC4090 | C20H34O2 | Ent-Isopimara-15-En-Α,Α-Diol | 306.2558803 | 1.6698 | 3.44 | 4.776 | 2 | 2 | 40.46 | 1 | 3 | 22 | 0 |
| TCMC5316 | C18H26O3 | 15,16-Bisnor-13-Oxo-8(17),11E-Labdadien-19-Oic Acid | 289.1803697 | 0.2683 | 3.11 | 3.593 | 3 | 0 | 57.2 | 3 | 2 | 21 | 0 |
| TCMC6496 | C18H28O3 | 15,16-Bisnor-13-Oxo-8(17)-Labden-19-Oic Acid | 291.1960197 | 0.0682 | 3.11 | 3.597 | 3 | 0 | 57.2 | 4 | 2 | 21 | 0 |
| TCMC680 | C30H18O10 | Amentoflavone | 538.09 | -3.769 | 3.66 | 2.302 | 2 | 6 | 173.98 | 9 | 6 | 40 | 1 |
Showing 1 to 8 of 8 entries
Download Data
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