Component: Cnidium monnieri 蛇床子


Description of the Component

Component ID
TCMH1866
Latin Name
Cnidium monnieri
English Name
Common cnidium
Chinese Pinyin Name
She Chuang Zi
中文名
蛇床子
TCM Properties
Warm,Pungent,Bitter
TCM Meridians
Kidney
Therapeutic Class English
For tonifying weakness
Therapeutic Class Chinese
补虚
Functions
warm the kidney and promote virility, remove damp, dispel zvind, and kill parasites
Toxicity
NA
Geo-authentic habitats (道地产区)
Hebei Province,Beijing,Tianjin
Reference
Chinese Pharmacopoeia (2015)
Barcode ID
ITSAL2575-14
Barcode Source
BOLDSYSTEMS

TCM Prescriptions with the Component

Prescription ID Prescription English Name Prescription Chinese Name
TCMFx6944 Ba Zi Bu Shen Capsules 八子补肾胶囊
TCMF2009 Bitter Seng Itching Stoper Decoction 苦参止痒汤
TCMFx6897 Bu Shen Yang Xue Capsules 补肾养血胶囊
TCMFx3035 Bu Tian Ling Tablets 补天灵片
TCMF890 Can E Gong Bu Tablet 蚕蛾公补片
TCMF3787 Can E Gong Bu Tablets 蚕蛾公补片
TCMF3123 Chang E Jia Li Pills 嫦娥加丽丸
TCMFx7035 Chuan Bai Zhi Yang Xi Ji 川百止痒洗剂
TCMF3700 Da Hu Zhuang Yuan Pills 打虎壮元丸
TCMFx3418 Die Da Wan Hua You 跌打万花油
TCMFx172 E Zhang Feng Yao Shui 鹅掌风药水
TCMF3087 Er Yi Pills 二益丸
TCMF3375 Feng Shi Gao Yao 风湿膏药
TCMF3756 Fu Bao Jin Pills 妇宝金丸
TCMFx36 Fu Bi Shu Yin Dao Pao Teng Tablets 妇必舒阴道泡腾片
TCMF537 Fu Ning Kang Tablet 妇宁康片
TCMF3021 Fu Ning Kang Tablets 妇宁康片
TCMFx3085 Fu Yan Ling Capsules 妇炎灵胶囊
TCMFx7037 Fu Yan Ling Pao Teng Tablets 妇炎灵泡腾片
TCMFx3093 Fu Yan Ping Capsules 妇炎平胶囊
TCMFx3101 Fu Yan Ping Powder 妇炎平散
TCMF1450 Goupi Plaster 狗皮膏
TCMF2631 Goupi Plaster, Dog-skin Plaster 狗皮膏
TCMFx4090 Hai Long Ge Jie Oral Liquid 海龙蛤蚧口服液
TCMFx4107 Hai Ma Ba Ji Capsules 海马巴戟胶囊
TCMFx4129 Hai Ma San Shen Pills 海马三肾丸
TCMF7082 Jie Er Yin Pao Teng Tablets 洁尔阴泡腾片
TCMF6977 Jie Er Yin Xi Oral Liquid 洁尔阴洗液
TCMF7137 Jin Chan Zhi Yang Granules 金蝉止痒颗粒
TCMF6973 Jin Zhi Jie Yin Han Shu Oral Liquid 金栀洁龈含漱液
TCMFx1070 Kang Fu Ointment 康妇软膏
TCMFx4893 Kang Fu Ruan Ointment 康妇软膏
TCMFx4447 Ke Yang Min Xu 克痒敏醑
TCMF7236 Ku Bai Zhi Yang Xi Oral Liquid 苦柏止痒洗液
TCMF6983 Ku Bai Zhi Yang Xi Oral Liquid 苦柏止痒洗液
TCMFx4384 Mei Ling Pills 媚灵丸
TCMF2529 Pellet for Impotence 赞育丹
TCMF6949 Pi Min Xiao Capsules 皮敏消胶囊
TCMF4918 Qi Rong Tablets 杞蓉片
TCMFx5174 Qu Feng Shi Zhi Tong Powder 祛风湿止痛散
TCMF2299 Roundworm Killing Decoction
TCMFx5871 San Bian Bu Wine 三鞭补酒
TCMFx5694 Shang Ke Wan Hua You 伤科万花油
TCMF5445 Shen Bao Recipe 肾宝合剂
TCMF5453 Shen Bao Syrup 肾宝糖浆
TCMF701 Shen Bao Syrup 肾宝糖浆
TCMF700 Shen Bao Recipe 肾宝合剂
TCMFx6958 Shen Di Yi Shen Oral Liquid 参地益肾口服液
TCMFx5328 Shen Hai Long Capsules 深海龙胶囊
TCMFx5336 Shen Hai Long Pills 深海龙丸
TCMF5673 Sheng Fa Pills 生发丸
TCMFx5725 Sheng Li Xiong Pills 生力雄丸
TCMFx5885 Shi Zhen Powder 湿疹散
TCMFx7218 Shuang Zi Shen Xi Oral Liquid 双子参洗液
TCMFx5181 Suo Yang Bu Shen Capsules 锁阳补肾胶囊
TCMFx5342 Te Zhi Gou Pi Ointment 特制狗皮膏
TCMFx2162 Wu Decoction
TCMFx5275 Wu She Zhi Yang Pills 乌蛇止痒丸
TCMFx422 Wu She Zhi Yang Pills 乌蛇止痒丸
TCMFx6405 Xiao Yan Xuan Shi Yao Ointment 消炎癣湿药膏
TCMFx6859 Xin Fu Man Ling Ruan Ointment 新肤螨灵软膏
TCMFx1189 Xuan Shi Solution 癣湿药水
TCMFx6638 Yan Ling Chang Chun Capsules 延龄长春胶囊
TCMFx6753 Yang Chun Yu Oral Liquid 阳春玉液
TCMF6133 Yao Shen Ointment 腰肾膏
TCMFx6374 Yi He Chun Capsules 颐和春胶囊
TCMFx6770 Zhi Bao San Bian Capsules 至宝三鞭胶囊
TCMFx6778 Zhi Bao San Bian Jing 至宝三鞭精
TCMFx6790 Zhi Bao San Bian Pills 至宝三鞭丸
TCMFx6784 Zhi Bao San Bian Wine 至宝三鞭酒
TCMF6164 Zhi Shu Shi Xi Oral Liquid 痔舒适洗液
TCMFx6744 Zhi Yang Xiao Yan Decoction 止痒消炎水
TCMFx6524 Zhuang Yang Chun Oral Liquid 壮阳春口服液
TCMFx6774 Zi Gong Ding 子宫锭

Targeted Human Proteins by the Ingredient of Component

Target ID Gene Symbol Target Name Target Class Uniprot ID
TCMT1 EHMT2 Histone-lysine N-methyltransferase, H3 lysine-9 specific 3 Transferase Q96KQ7
TCMT101 PTPN1 Protein-tyrosine phosphatase 1B Hydrolase P18031
TCMT125 GBA Beta-glucocerebrosidase Hydrolase P04062
TCMT131 ACHE Acetylcholinesterase Hydrolase P22303
TCMT133 CA1 Carbonic anhydrase I Lyase P00915
TCMT134 CA2 Carbonic anhydrase II Lyase P00918
TCMT135 CA14 Carbonic anhydrase XIV Lyase Q9ULX7
TCMT136 CA12 Carbonic anhydrase XII Lyase O43570
TCMT137 CA9 Carbonic anhydrase IX Lyase Q16790
TCMT138 CA7 Carbonic anhydrase VII Lyase P43166
TCMT139 CA6 Carbonic anhydrase VI Lyase P23280
TCMT140 CA5B Carbonic anhydrase VB Lyase Q9Y2D0
TCMT141 CA5A Carbonic anhydrase VA Lyase P35218
TCMT142 CA4 Carbonic anhydrase IV Lyase P22748
TCMT143 CA3 Carbonic anhydrase III Lyase P07451
TCMT150 RORC Nuclear receptor ROR-gamma Nuclear receptor P51449
TCMT156 CYP19A1 Cytochrome P450 19A1 Oxidoreductase P11511
TCMT160 HTR7 Serotonin 7 (5-HT7) receptor GPCR P34969
TCMT17 POLB DNA polymerase beta Transferase P06746
TCMT18 GAA Lysosomal alpha-glucosidase Hydrolase P10253
TCMT189 DUSP3 Dual specificity protein phosphatase 3 Hydrolase P51452
TCMT2 MAPT Microtubule-associated protein tau Unclassified P10636
TCMT206 CYP2A6 Cytochrome P450 2A6 Oxidoreductase P11509
TCMT207 BACE1 Beta-secretase 1 Protease P56817
TCMT208 MAOA Monoamine oxidase A Oxidoreductase P21397
TCMT215 CYP1A1 Cytochrome P450 1A1 Oxidoreductase P04798
TCMT219 CYP1A2 Cytochrome P450 1A2 Oxidoreductase P05177
TCMT223 AKR1B1 Aldose reductase Oxidoreductase P15121
TCMT225 CA13 Carbonic anhydrase XIII Lyase Q8N1Q1
TCMT232 ABCB1 P-glycoprotein 1 Transporter P08183
TCMT240 AMY1A Salivary alpha-amylase Unclassified P04745
TCMT257 CYP1B1 Cytochrome P450 1B1 Oxidoreductase Q16678
TCMT268 CYP2A13 Cytochrome P450 2A13 Oxidoreductase Q16696
TCMT276 SLCO2B1 Solute carrier organic anion transporter family member 2B1 Transporter O94956
TCMT277 SLCO1B3 Solute carrier organic anion transporter family member 1B3 Transporter Q9NPD5
TCMT278 SLCO1B1 Solute carrier organic anion transporter family member 1B1 Transporter Q9Y6L6
TCMT281 DPP4 Dipeptidyl peptidase IV Unclassified P27487
TCMT297 FABP4 Fatty acid binding protein adipocyte Unclassified P15090
TCMT298 FABP3 Fatty acid binding protein muscle Hydrolase P05413
TCMT31 CYP2C19 Cytochrome P450 2C19 Oxidoreductase P33261
TCMT33 CYP3A4 Cytochrome P450 3A4 Oxidoreductase P08684
TCMT333 CTBP2 C-terminal-binding protein 2 Unclassified P56545
TCMT337 XPO1 Exportin-1 Unclassified O14980
TCMT34 CYP2D6 Cytochrome P450 2D6 Oxidoreductase P10635
TCMT41 IDH1 Isocitrate dehydrogenase [NADP] cytoplasmic Oxidoreductase O75874
TCMT42 KMT2A Histone-lysine N-methyltransferase MLL Transferase Q03164
TCMT506 PTK2B Protein tyrosine kinase 2 beta Kinase Q14289
TCMT63 PPARA Peroxisome proliferator-activated receptor alpha Nuclear receptor Q07869
TCMT64 PPARD Peroxisome proliferator-activated receptor delta Nuclear receptor Q03181
TCMT67 PPARG Peroxisome proliferator-activated receptor gamma Nuclear receptor P37231
TCMT8 KDM4E Lysine-specific demethylase 4D-like Oxidoreductase B2RXH2
TCMT80 MAPK1 MAP kinase ERK2 Kinase P28482
TCMT808 FABP5 Fatty acid binding protein epidermal Unclassified Q01469
TCMT809 FABP2 Fatty acid binding protein intestinal Unclassified P12104
TCMT810 TLR2 Toll-like receptor 2 Unclassified O60603
TCMT82 ESR1 Estrogen receptor alpha Nuclear receptor P03372
TCMT87 CYP2C9 Cytochrome P450 2C9 Oxidoreductase P11712


Targeted Pathogenic Microbes by the Ingredient of Component

Target ID Target Name
TCMT1112 Quinolone resistance protein norA
TCMT1214 Enterococcus faecium
TCMT1218 Staphylococcus aureus
TCMT1229 Enterococcus faecalis
TCMT1243 Aspergillus flavus
TCMT1255 Human immunodeficiency virus 1
TCMT1349 Helicobacter pylori SS1
TCMT1354 Streptococcus mutans UA159
TCMT1361 Neisseria meningitidis
TCMT1382 Plasmodium falciparum (isolate K1 / Thailand)
TCMT1393 Vibrio sp.
TCMT1438 Plasmodium falciparum
TCMT1442 Leishmania donovani
TCMT1454 Bacillus subtilis
TCMT1462 Streptococcus mutans
TCMT1463 Mycobacterium tuberculosis
TCMT1465 Entamoeba histolytica

Ingredient Structrues

Ingredient ID: TCMC949
Formula: C9H6O2

Ingredient ID: TCMC936
Formula: C14H14O4

Ingredient ID: TCMC935
Formula: C19H20O5

Ingredient ID: TCMC801
Formula: C29H50O

Ingredient ID: TCMC787
Formula: C12H8O4

Ingredient ID: TCMC7239
Formula: C18H20O5

Ingredient ID: TCMC671
Formula: C10H16

Ingredient ID: TCMC6617
Formula: C15H14O5

Ingredient ID: TCMC6601
Formula: C20H22O7

Ingredient ID: TCMC6417
Formula: C17H20O9

Ingredient ID: TCMC5325
Formula: C15H24

Ingredient ID: TCMC5032
Formula: C10H18O

Ingredient ID: TCMC4715
Formula: C9H14O

Ingredient ID: TCMC4449
Formula: C13H8O4

Ingredient ID: TCMC4338
Formula: C15H24

Ingredient ID: TCMC4336
Formula: C15H24

Ingredient ID: TCMC405
Formula: C20H19N3O2

Ingredient ID: TCMC3966
Formula: C29H50O

Ingredient ID: TCMC3597
Formula: C16H16O5

Ingredient ID: TCMC3310
Formula: C15H26O

Ingredient ID: TCMC3296
Formula: C15H24

Ingredient ID: TCMC3295
Formula: C15H24

Ingredient ID: TCMC3274
Formula: C10H16

Ingredient ID: TCMC3226
Formula: C16H14O4

Ingredient ID: TCMC3013
Formula: C15H24

Ingredient ID: TCMC2931
Formula: C10H16

Ingredient ID: TCMC2901
Formula: C10H16

Ingredient ID: TCMC2896
Formula: C12H20O2

Ingredient ID: TCMC284
Formula: C10H16

Ingredient ID: TCMC2822
Formula: C15H24

Ingredient ID: TCMC2718
Formula: C21H24O6

Ingredient ID: TCMC2696
Formula: C28H56O2

Ingredient ID: TCMC2550
Formula: C15H24

Ingredient ID: TCMC2324
Formula: C10H16

Ingredient ID: TCMC2242
Formula: C15H14O4

Ingredient ID: TCMC2241
Formula: C11H6O4

Ingredient ID: TCMC213
Formula: C21H22O7

Ingredient ID: TCMC1961
Formula: C11H6O3

Ingredient ID: TCMC1858
Formula: C16H14O4

Ingredient ID: TCMC1830
Formula: C16H32O2

Ingredient ID: TCMC1803
Formula: C15H16O3

Ingredient ID: TCMC1611
Formula: C14H28O2

Ingredient ID: TCMC1551
Formula: C12H8O4

Ingredient ID: TCMC1404
Formula: C13H10O5

Ingredient ID: TCMC1100
Formula: C20H40O2

Ingredient ID: TCMC1064
Formula: C16H12O6

Properties

Ingredient ID Formulae Name MW AlogP MlogP XlogP # HBA # HBD PSA # Rotatable Bond # Ring # Heacy Atom Lipinski RO5 Violation
TCMC213 C21H22O7 [(8S,9R)-8-(2-Acetyloxypropan-2-Yl)-2-Oxo-8,9-Dihydrofuro[2,3-H]Chromen-9-Yl] (Z)-2-Methylbut-2-Enoate 386.14 1.7906 3 3.54 5 0 88.13 11 3 28 0
TCMC284 C10H16 1-Methyl-4-Prop-1-En-2-Ylcyclohexene 136.13 2.1424 2.56 3.729 0 0 0 3 1 10 0
TCMC405 C20H19N3O2 3-(1H-Benzimidazol-2-Yl)-7-(Diethylamino)Chromen-2-One 333.15 0.4793 3.11 4.231 4 1 58.22 6 4 25 0
TCMC671 C10H16 Alpha-Pinene 136.13 1.5162 2.56 4.177 0 0 0 3 1 10 0
TCMC787 C12H8O4 Bergapten 216.04 0.0641 2.34 1.69 1 0 48.67 2 3 16 0
TCMC801 C29H50O Beta-Sitosterol 414.39 1.3 4.54 11.595 1 1 20.23 13 4 30 1
TCMC935 C19H20O5 Columbianadin 328.13 1.9846 3 3.83 3 0 61.83 8 3 24 0
TCMC936 C14H14O4 Columbianetin 246.09 0.2617 2.56 2.093 2 1 55.76 4 3 18 0
TCMC949 C9H6O2 Coumarin 146.04 0.27 2.23 2.706 1 0 26.3 0 2 11 0
TCMC1064 C16H12O6 Diosmetin 300.06 -1.9363 2.56 1.123 1 3 96.22 6 3 22 0
TCMC1100 C20H40O2 Elcosanoic Acid 312.3 -5.0497 3.44 9.846 2 1 37.3 20 0 22 2
TCMC1404 C13H10O5 Isopimpinellin 246.05 0.0123 2.34 1.246 1 0 57.9 4 3 18 0
TCMC1551 C12H8O4 Methoxsalen 216.04 0.0641 2.34 1.69 1 0 48.67 2 3 16 0
TCMC1611 C14H28O2 Myristic Acid 228.21 -3.3217 2.78 6.432 2 1 37.3 14 0 16 2
TCMC1803 C15H16O3 Osthole 244.11 2.0956 2.78 3.521 1 0 35.53 6 2 18 0
TCMC1830 C16H32O2 Palmitic Acid 256.24 -3.8977 3 7.57 2 1 37.3 16 0 18 2
TCMC1858 C16H14O4 Pentosalen 270.09 1.5296 2.78 2.891 1 0 48.67 5 3 20 0
TCMC1961 C11H6O3 Psoralen 186.03 0.1159 2.34 2.134 1 0 39.44 0 3 14 0
TCMC2241 C11H6O4 Xanthotoxol 202.03 -0.3444 2.23 1.171 1 1 59.67 1 3 15 0
TCMC2242 C15H14O4 Xanthoxyletin 258.09 1.126 2.67 2.488 1 0 44.76 4 3 19 0
TCMC2324 C10H16 Limonene 136.13 2.1424 2.56 3.729 0 0 0 3 1 10 0
TCMC2550 C15H24 (+)-Germacrene D 204.19 2.7967 3.11 6.294 0 0 0 4 1 15 1
TCMC2696 C28H56O2 N-Octacosanoic Acid 424.43 -7.3537 4.32 14.398 2 1 37.3 28 0 30 2
TCMC2718 C21H24O6 Isovaleryl Alkannin 372.16 0.9953 3.11 2.499 4 2 100.9 13 2 27 0
TCMC2822 C15H24 Alpha-Humulone 204.19 4.1708 3.11 5.94 0 0 0 4 1 15 1
TCMC2896 C12H20O2 1,7,7-Trimethylbicyclo[2.2.1]Heptan-2-Yl Acetate,Bornyl Acetate 196.1463299 1.3223 2.56 3.474 2 0 26.3 2 2 14 0
TCMC2901 C10H16 2,2-Dimethyl-3-Methylenebicyclo[2.2.1]Heptane,Camphene 136.1252005 1.3875 2.56 4.024 0 0 0 0 2 10 0
TCMC2931 C10H16 1-Isopropyl-4-Methylcyclohexa-1,3-Diene,Terpilene,Α-Terpinene 136.1252005 1.8841 2.56 3.546 0 0 0 1 1 10 0
TCMC3013 C15H24 Α-Elemene,Β-Elemene 204.1878008 3.2309 3.11 6.071 0 0 0 3 1 15 1
TCMC3226 C16H14O4 Alloimperatorin 270.0892089 1.6008 2.78 3.376 1 1 50.44 2 3 20 0
TCMC3274 C10H16 Cyclofenchene 136.1252005 1.2281 2.56 4.779 0 0 0 0 1 10 0
TCMC3295 C15H24 Α-Bergamotene 204.1878008 2.7484 3.11 6.104 0 0 0 3 1 15 1
TCMC3296 C15H24 Α-Cubebene 204.1878008 1.6446 3.11 6.499 0 0 0 1 3 15 1
TCMC3310 C15H26O Beta-Eudesmol 222.1983655 0.6981 3 4.83 1 1 20.23 1 2 16 0
TCMC3597 C16H16O5 Columbianetin Acetate 288.0997736 0.7086 2.67 3.357 3 0 52.6 3 3 21 0
TCMC3966 C29H50O Sitosterol,Β-Sitosterol 414.3861662 1.3 4.54 11.595 1 1 20.23 6 4 30 1
TCMC4336 C15H24 (1R,9S)-4,11,11-Trimethyl-8-Methylenebicyclo[7.2.0]Undec-4-Ene,Caryophellene,Β-Caryophyllene 204.1878008 3.2289 3.11 6.044 0 0 0 0 2 15 1
TCMC4338 C15H24 7,11-Dimethyl-3-Methylenedodeca-1,6,10-Triene,Β-Farnesene 204.1878008 4.3258 3.11 5.992 0 0 0 7 0 15 1
TCMC4449 C13H8O4 2'-Acetylangelicin 228.0422587 -0.0702 2.45 2.548 2 0 47.28 1 3 17 0
TCMC4715 C9H14O 1(7),8(10)-P-Menthadien-9-Ol 138.1044651 0.9862 2.34 2.243 1 1 20.23 1 1 10 0
TCMC5032 C10H18O (1R,2R,4R)-1,7,7-Trimethylbicyclo[2.2.1]Heptan-2-Ol,Isoborneol,L-Isoborneol 154.1357652 0.9432 2.45 2.734 1 1 20.23 0 2 11 0
TCMC5325 C15H24 (S)-1-Methyl-4-(6-Methylhepta-1,5-Dien-2-Yl)Cyclohex-1-Ene,Β-Bisabolene 204.1878008 3.3746 3.11 5.551 0 0 0 4 1 15 1
TCMC6417 C17H20O9 Cnidioside A 367.1029072 -3.1817 2.34 -0.53 7 4 152.65 6 3 26 0
TCMC6601 C20H22O7 3'-Isobutyryloxy-O-Acetyl-2',3'-Dihydro-Oroselol 374.136553 1.239 2.89 3.613 5 0 78.9 6 3 27 0
TCMC6617 C15H14O5 Umtatin 274.0841235 -0.2472 2.56 -0.136 2 2 66.76 2 3 20 0
TCMC7239 C18H20O5 Cnidiadin 316.1310737 1.433 2.89 3.903 3 0 52.6 4 3 23 0

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1. General Information of the Component  
2. TCM Prescriptions with the Component  
3. Putative Targets  
4. Activity & References for Filtering Putative Targets  
5. Ingredient Data & Chemical Structure Information (Properties, InChI, InChIkey, SMILES, etc.)