GO Term |
GO Name |
Enriched Genes |
Log10 Adjusted P-value |
[BP] GO:0006629 |
lipid metabolic process
|
ACHE, ADORA1, AKR1B1, AKR1C3, ALOX5, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, ESR1, FABP4, HSD17B1, KIT, MET, MIF, PPARA |
7.69868 |
[BP] GO:0019748 |
secondary metabolic process
|
AKR1B1, AKR1C3, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6 |
7.15598 |
[BP] GO:0033993 |
response to lipid
|
AKR1C3, ALPL, AXL, CA9, CNR1, CNR2, CSNK2A1, CYP1A1, CYP1A2, ESR1, ESRRA, FLT3, IDO1, RORC, SRC |
7.15598 |
[BP] GO:0010033 |
response to organic substance
|
AKR1B1, AKR1C3, ALPL, AXL, CA9, CNR1, CNR2, CSNK2A1, CYP1A1, CYP1A2, CYP1B1, ESR1, ESRRA, FABP4, FLT3, IDO1, IGF1R, KDR, KIT, PPARA, RORC, SRC |
7.13739 |
[BP] GO:0033559 |
unsaturated fatty acid metabolic process
|
AKR1C3, ALOX5, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, MIF |
6.9874 |
[BP] GO:0010941 |
regulation of cell death
|
ADORA1, AKR1B1, AKR1C3, AURKB, AXL, CNR1, CSNK2A1, CYP1B1, ESR1, FLT3, IDO1, IGF1R, KDR, KIT, MET, MIF, PIM1, PPARA, SRC, XDH |
6.918 |
[BP] GO:0006690 |
icosanoid metabolic process
|
AKR1C3, ALOX5, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, MIF |
6.89337 |
[BP] GO:1901700 |
response to oxygen-containing compound
|
AKR1B1, AKR1C3, ALPL, AXL, CA9, CNR1, CNR2, CSNK2A1, CYP1A1, CYP1A2, CYP1B1, ESR1, ESRRA, IDO1, IGF1R, PPARA, RORC, SRC |
6.89337 |
[BP] GO:0043067 |
regulation of programmed cell death
|
ADORA1, AKR1B1, AKR1C3, AURKB, AXL, CNR1, CSNK2A1, CYP1B1, ESR1, FLT3, IDO1, IGF1R, KDR, KIT, MET, MIF, PIM1, SRC, XDH |
6.70448 |
[BP] GO:0019373 |
epoxygenase P450 pathway
|
CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6 |
5.98691 |
[BP] GO:0044281 |
small molecule metabolic process
|
AKR1B1, AKR1C3, ALOX5, AOX1, CA12, CA4, CA7, CA9, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, IDO1, MIF, PIM1, PPARA, XDH |
5.94802 |
[BP] GO:0048523 |
negative regulation of cellular process
|
ACHE, ADORA1, ADORA3, AKR1B1, AKR1C3, AURKB, AXL, CNR1, CNR2, CSNK2A1, CYP19A1, CYP1B1, ESR1, ESR2, ESRRA, ESRRB, FABP4, IDO1, IGF1R, KDR, KIT, MET, MIF, MMP12, PIM1, PPARA, RORC, SRC, XDH |
5.86792 |
[BP] GO:0042221 |
response to chemical
|
AKR1B1, AKR1C3, ALPL, AXL, CA9, CNR1, CNR2, CSNK2A1, CYP1A1, CYP1A2, CYP1B1, ESR1, ESRRA, FABP4, FLT3, IDO1, IGF1R, KDR, KIT, PPARA, RORC, SRC |
5.86257 |
[BP] GO:1901568 |
fatty acid derivative metabolic process
|
AKR1C3, ALOX5, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, MIF |
5.86257 |
[BP] GO:0019369 |
arachidonic acid metabolic process
|
AKR1C3, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6 |
5.78836 |
[BP] GO:0008202 |
steroid metabolic process
|
AKR1B1, AKR1C3, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A6, ESR1, HSD17B1 |
5.62474 |
[BP] GO:0014070 |
response to organic cyclic compound
|
AKR1C3, ALPL, CA9, CNR1, CSNK2A1, CYP1A1, CYP1A2, CYP1B1, ESR1, ESRRA, FLT3, RORC, SRC |
5.59898 |
[BP] GO:0042127 |
regulation of cell proliferation
|
ADORA1, ADORA3, AKR1B1, AKR1C3, CSNK2A1, CYP1B1, ESR1, ESRRA, FLT3, IDO1, IGF1R, KDR, KIT, MIF, MMP12, PIM1, SRC, XDH |
5.59898 |
[BP] GO:0034754 |
cellular hormone metabolic process
|
AKR1B1, AKR1C3, CYP19A1, CYP1A1, CYP1B1, ESR1, HSD17B1 |
5.59724 |
[BP] GO:0030522 |
intracellular receptor signaling pathway
|
ESR1, ESR2, ESRRA, ESRRB, PIM1, PPARA, RORC, SRC |
5.56224 |
[BP] GO:0042445 |
hormone metabolic process
|
ACHE, AKR1B1, AKR1C3, CYP19A1, CYP1A1, CYP1B1, ESR1, HSD17B1 |
5.40907 |
[BP] GO:0042981 |
regulation of apoptotic process
|
ADORA1, AKR1B1, AKR1C3, AURKB, AXL, CNR1, CSNK2A1, CYP1B1, ESR1, FLT3, IDO1, IGF1R, KDR, MIF, PIM1, SRC, XDH |
5.33849 |
[BP] GO:0060548 |
negative regulation of cell death
|
ADORA1, AKR1B1, AURKB, AXL, CSNK2A1, IDO1, IGF1R, KDR, KIT, MET, MIF, PIM1, PPARA, SRC |
5.29377 |
[BP] GO:0046777 |
protein autophosphorylation
|
AURKB, CSNK2A1, FLT3, IGF1R, KDR, KIT, PIM1, SRC |
5.26739 |
[BP] GO:0044255 |
cellular lipid metabolic process
|
ACHE, AKR1C3, ALOX5, CSNK2A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, FABP4, KIT, MET, MIF, PPARA |
5.23985 |
[BP] GO:0048522 |
positive regulation of cellular process
|
ACHE, ADORA1, AKR1B1, AKR1C3, AURKB, AXL, CA7, CNR1, CSNK2A1, CYP19A1, CYP1A1, CYP1B1, ESR1, ESR2, ESRRA, ESRRB, FLT3, IDO1, IGF1R, KDR, KIT, MET, MIF, MMP12, PIM1, PPARA, RORC, SRC, XDH |
5.20296 |
[BP] GO:0009725 |
response to hormone
|
AKR1B1, AKR1C3, ALPL, CA9, CSNK2A1, CYP1A2, ESR1, ESRRA, FLT3, KIT, PPARA, SRC |
5.19539 |
[BP] GO:0065008 |
regulation of biological quality
|
ACHE, ADORA1, AKR1B1, AKR1C3, AURKB, AXL, CA12, CA7, CNR1, CNR2, CYP19A1, CYP1A1, CYP1B1, ESR1, FABP4, FLT3, HSD17B1, KDR, KIT, MET, MIF, PPARA, SRC, XDH |
5.19539 |
[BP] GO:0043401 |
steroid hormone mediated signaling pathway
|
ESR1, ESR2, ESRRA, ESRRB, PPARA, RORC, SRC |
5.18798 |
[BP] GO:0006631 |
fatty acid metabolic process
|
AKR1C3, ALOX5, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, MIF, PPARA |
5.17479 |
[BP] GO:0048519 |
negative regulation of biological process
|
ACHE, ADORA1, ADORA3, AKR1B1, AKR1C3, AURKB, AXL, CNR1, CNR2, CSNK2A1, CYP19A1, CYP1B1, ESR1, ESR2, ESRRA, ESRRB, FABP4, IDO1, IGF1R, KDR, KIT, MET, MIF, MMP12, PIM1, PPARA, RORC, SRC, XDH |
5.13785 |
[BP] GO:0048513 |
animal organ development
|
ACHE, AKR1C3, AXL, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, ESR1, ESRRA, ESRRB, FLT3, KDR, KIT, PPARA, SRC |
5.09337 |
[BP] GO:0043069 |
negative regulation of programmed cell death
|
ADORA1, AKR1B1, AURKB, AXL, CSNK2A1, IDO1, IGF1R, KDR, KIT, MET, MIF, PIM1, SRC |
4.91291 |
[BP] GO:0008152 |
metabolic process
|
ACHE, ADORA1, AKR1B1, AKR1C3, ALOX5, ALPL, AOX1, AURKB, AXL, CA12, CA4, CA7, CA9, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, ESR1, ESR2, ESRRA, ESRRB, FABP4, FLT3, HSD17B1, IDO1, IGF1R, KDR, KIT, MET, MIF, MMP12, PIM1, PPARA, RORC, SRC, XDH |
4.88179 |
[BP] GO:0048518 |
positive regulation of biological process
|
ACHE, ADORA1, AKR1B1, AKR1C3, AURKB, AXL, CA7, CNR1, CSNK2A1, CYP19A1, CYP1A1, CYP1B1, ESR1, ESR2, ESRRA, ESRRB, FABP4, FLT3, IDO1, IGF1R, KDR, KIT, MET, MIF, MMP12, PIM1, PPARA, RORC, SRC, XDH |
4.79159 |
[BP] GO:0055114 |
oxidation-reduction process
|
AKR1B1, AKR1C3, ALOX5, AOX1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, HSD17B1, IDO1, XDH |
4.79159 |
[BP] GO:0015701 |
bicarbonate transport
|
CA12, CA14, CA4, CA7, CA9 |
4.79159 |
[BP] GO:0010035 |
response to inorganic substance
|
AKR1B1, AKR1C3, AXL, CYP1A1, CYP1A2, CYP1B1, FABP4, KDR, KIT, SRC |
4.7337 |
[BP] GO:0032787 |
None
|
AKR1C3, ALOX5, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, IDO1, MIF, PPARA |
4.59385 |
[BP] GO:0009755 |
hormone-mediated signaling pathway
|
ESR1, ESR2, ESRRA, ESRRB, PPARA, RORC, SRC |
4.57094 |
[BP] GO:0019216 |
regulation of lipid metabolic process
|
ADORA1, AKR1C3, CNR1, CYP1A1, FLT3, KIT, PPARA, RORC, SRC |
4.55213 |
[BP] GO:0044237 |
cellular metabolic process
|
ACHE, AKR1B1, AKR1C3, ALOX5, ALPL, AOX1, AURKB, AXL, CA12, CA4, CA7, CA9, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, ESR1, ESR2, ESRRA, ESRRB, FABP4, FLT3, HSD17B1, IDO1, IGF1R, KDR, KIT, MET, MIF, PIM1, PPARA, RORC, SRC, XDH |
4.55213 |
[BP] GO:0001676 |
long-chain fatty acid metabolic process
|
AKR1C3, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6 |
4.55171 |
[BP] GO:0032101 |
regulation of response to external stimulus
|
ADORA1, CNR1, CNR2, CYP19A1, ESR1, FABP4, IDO1, KDR, MET, MIF, MMP12, PPARA |
4.54213 |
[BP] GO:0010646 |
regulation of cell communication
|
ACHE, ADORA1, AKR1B1, AKR1C3, AURKB, AXL, CA7, CNR1, CNR2, CSNK2A1, CYP19A1, CYP1B1, ESR1, ESR2, FLT3, IGF1R, KDR, KIT, MET, MIF, MMP12, SRC, XDH |
4.53319 |
[BP] GO:0023051 |
regulation of signaling
|
ACHE, ADORA1, AKR1B1, AKR1C3, AURKB, AXL, CA7, CNR1, CNR2, CSNK2A1, CYP19A1, CYP1B1, ESR1, ESR2, FLT3, IGF1R, KDR, KIT, MET, MIF, MMP12, SRC, XDH |
4.4431 |
[BP] GO:0048583 |
regulation of response to stimulus
|
ADORA1, AKR1B1, AKR1C3, AURKB, AXL, CNR1, CNR2, CSNK2A1, CYP19A1, CYP1B1, ESR1, ESR2, ESRRA, FABP4, FLT3, IDO1, IGF1R, KDR, KIT, MET, MIF, MMP12, PPARA, SRC, XDH |
4.42493 |
[BP] GO:0009719 |
response to endogenous stimulus
|
AKR1B1, AKR1C3, ALPL, CA9, CSNK2A1, CYP1A2, ESR1, ESRRA, FLT3, IGF1R, KIT, PPARA, SRC |
4.41808 |
[BP] GO:0010817 |
regulation of hormone levels
|
ACHE, ADORA1, AKR1B1, AKR1C3, CNR1, CYP19A1, CYP1A1, CYP1B1, ESR1, HSD17B1 |
4.41808 |
[BP] GO:0032501 |
multicellular organismal process
|
ADORA1, AKR1B1, AKR1C3, ALOX5, ALPL, AXL, CNR1, CNR2, CYP19A1, CYP1A2, CYP1B1, ESR1, ESRRB, FABP4, IDO1, IGF1R, KIT, MET, MMP12, PIM1, PPARA, RORC, SRC |
4.39544 |
[BP] GO:0032502 |
developmental process
|
ACHE, ADORA1, AKR1B1, AKR1C3, ALPL, AURKB, AXL, CA9, CNR1, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, ESR1, ESRRA, ESRRB, FABP4, FLT3, KDR, KIT, MET, MIF, PIM1, PPARA, RORC, SRC |
4.39163 |
[BP] GO:0032496 |
response to lipopolysaccharide
|
ALPL, AXL, CNR1, CNR2, CYP1A1, CYP1A2, IDO1, SRC |
4.38935 |
[BP] GO:0018108 |
peptidyl-tyrosine phosphorylation
|
AXL, FLT3, IGF1R, KDR, KIT, MET, SRC |
4.35879 |
[BP] GO:0018212 |
peptidyl-tyrosine modification
|
AXL, FLT3, IGF1R, KDR, KIT, MET, SRC |
4.31675 |
[BP] GO:0009636 |
response to toxic substance
|
AKR1B1, ALPL, AXL, CNR1, CNR2, CYP1A1, CYP1B1, KDR, SRC |
4.28103 |
[BP] GO:0071310 |
cellular response to organic substance
|
AKR1B1, AKR1C3, ALPL, AXL, CYP1A1, CYP1B1, ESR1, FABP4, FLT3, IGF1R, KDR, KIT, RORC, SRC |
4.27558 |
[BP] GO:0010647 |
positive regulation of cell communication
|
ADORA1, AKR1B1, AKR1C3, AXL, CA7, CSNK2A1, CYP19A1, CYP1B1, FLT3, KDR, KIT, MET, MIF, MMP12, SRC, XDH |
4.26697 |
[BP] GO:0023056 |
positive regulation of signaling
|
ADORA1, AKR1B1, AKR1C3, AXL, CA7, CSNK2A1, CYP19A1, CYP1B1, FLT3, KDR, KIT, MET, MIF, MMP12, SRC, XDH |
4.24675 |
[BP] GO:0002237 |
response to molecule of bacterial origin
|
ALPL, AXL, CNR1, CNR2, CYP1A1, CYP1A2, IDO1, SRC |
4.20539 |
[BP] GO:0048584 |
positive regulation of response to stimulus
|
ADORA1, AKR1B1, AKR1C3, AXL, CNR1, CSNK2A1, CYP1B1, ESRRA, FABP4, FLT3, IDO1, KDR, KIT, MET, MIF, MMP12, SRC, XDH |
4.1251 |
[BP] GO:0050896 |
response to stimulus
|
ACHE, ADORA1, ADORA3, AKR1B1, AKR1C3, ALPL, AURKB, AXL, CA9, CNR1, CNR2, CSNK2A1, CYP1A1, CYP1A2, CYP1B1, ESR1, ESRRA, FABP4, FLT3, IDO1, IGF1R, KDR, KIT, MIF, MMP12, PPARA, RORC, SRC |
4.08454 |
[BP] GO:0009698 |
phenylpropanoid metabolic process
|
CYP1A1, CYP2A13, CYP2A6 |
4.076 |
[BP] GO:0009804 |
coumarin metabolic process
|
CYP1A1, CYP2A13, CYP2A6 |
4.076 |
[BP] GO:0070887 |
cellular response to chemical stimulus
|
AKR1B1, AKR1C3, ALPL, AXL, CYP1A1, CYP1A2, CYP1B1, ESR1, FABP4, FLT3, IGF1R, KDR, KIT, RORC, SRC |
4.076 |
[BP] GO:0032228 |
regulation of synaptic transmission, GABAergic
|
ADORA1, CA7, CNR1, CNR2 |
3.78012 |
[BP] GO:1902531 |
regulation of intracellular signal transduction
|
ADORA1, AKR1B1, AKR1C3, AURKB, AXL, CSNK2A1, CYP1B1, ESR1, FLT3, IGF1R, KDR, KIT, MET, MIF, SRC, XDH |
3.73355 |
[BP] GO:0071407 |
cellular response to organic cyclic compound
|
AKR1C3, ALPL, CYP1A1, CYP1B1, ESR1, FLT3, RORC, SRC |
3.69889 |
[BP] GO:0044092 |
negative regulation of molecular function
|
ADORA3, AURKB, CNR1, CNR2, CSNK2A1, CYP1B1, ESR1, FABP4, IGF1R, MET, PIM1, PPARA, SRC |
3.69889 |
[BP] GO:0009056 |
catabolic process
|
ACHE, ADORA1, AKR1C3, AOX1, AURKB, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A6, FABP4, IDO1, MMP12, SRC, XDH |
3.69889 |
[BP] GO:1902533 |
positive regulation of intracellular signal transduction
|
ADORA1, AKR1B1, AKR1C3, AXL, CYP1B1, FLT3, KDR, KIT, MET, MIF, SRC, XDH |
3.68923 |
[BP] GO:0048856 |
anatomical structure development
|
ACHE, ADORA1, AKR1B1, AKR1C3, ALPL, AXL, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, ESR1, ESRRA, ESRRB, FLT3, KDR, KIT, PIM1, PPARA, RORC, SRC |
3.65463 |
[BP] GO:0006730 |
one-carbon metabolic process
|
CA12, CA4, CA7, CA9 |
3.60751 |
[BP] GO:0097267 |
omega-hydroxylase P450 pathway
|
CYP1A1, CYP1A2, CYP1B1 |
3.60107 |
[BP] GO:0008283 |
cell proliferation
|
ACHE, AURKB, CYP1A1, ESR1, FLT3, KIT, MET, MIF, PIM1, SRC |
3.5789 |
[BP] GO:0006367 |
transcription initiation from RNA polymerase II promoter
|
ESR1, ESR2, ESRRA, ESRRB, PPARA, RORC |
3.55605 |
[BP] GO:0022900 |
electron transport chain
|
AKR1B1, AOX1, CYP19A1, CYP1A2, IDO1, XDH |
3.52856 |
[BP] GO:0080134 |
regulation of response to stress
|
ADORA1, CNR1, CNR2, CYP19A1, ESR1, FABP4, IDO1, IGF1R, MET, MIF, MMP12, PPARA, SRC, XDH |
3.42875 |
[BP] GO:0043066 |
negative regulation of apoptotic process
|
ADORA1, AKR1B1, AURKB, AXL, CSNK2A1, IDO1, IGF1R, KDR, MIF, PIM1, SRC |
3.42875 |
[BP] GO:0050727 |
regulation of inflammatory response
|
ADORA1, CNR1, CNR2, CYP19A1, ESR1, FABP4, IDO1, PPARA |
3.42875 |
[BP] GO:0017144 |
drug metabolic process
|
ACHE, AKR1B1, AKR1C3, AOX1, CYP1A1, CYP1A2, CYP1B1, CYP2A6, IDO1 |
3.42658 |
[BP] GO:0019752 |
carboxylic acid metabolic process
|
AKR1C3, ALOX5, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, IDO1, MIF, PIM1, PPARA |
3.41975 |
[BP] GO:0008284 |
positive regulation of cell proliferation
|
AKR1B1, AKR1C3, CSNK2A1, ESR1, FLT3, IGF1R, KDR, KIT, MIF, MMP12, PIM1 |
3.30123 |
[BP] GO:0002683 |
negative regulation of immune system process
|
ADORA1, AXL, CNR1, CNR2, CYP19A1, IDO1, MIF, MMP12 |
3.30123 |
[BP] GO:0048511 |
rhythmic process
|
AXL, CSNK2A1, ESR1, KIT, PPARA, RORC, SRC |
3.28642 |
[BP] GO:0009967 |
positive regulation of signal transduction
|
ADORA1, AKR1B1, AKR1C3, AXL, CSNK2A1, CYP1B1, FLT3, KDR, KIT, MET, MIF, MMP12, SRC, XDH |
3.28249 |
[BP] GO:0044238 |
primary metabolic process
|
ACHE, ADORA1, AKR1B1, AKR1C3, ALOX5, ALPL, AOX1, AURKB, AXL, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, ESR1, ESR2, ESRRA, ESRRB, FABP4, FLT3, HSD17B1, IDO1, IGF1R, KDR, KIT, MET, MIF, MMP12, PIM1, PPARA, RORC, SRC, XDH |
3.20297 |
[BP] GO:2000107 |
negative regulation of leukocyte apoptotic process
|
AURKB, AXL, IDO1, MIF |
3.19924 |
[BP] GO:0060065 |
uterus development
|
CYP19A1, ESR1, SRC |
3.18645 |
[BP] GO:0034614 |
cellular response to reactive oxygen species
|
AKR1B1, AKR1C3, AXL, CYP1B1, SRC |
3.14844 |
[BP] GO:0009115 |
None
|
AOX1, XDH |
3.08094 |
[BP] GO:0051716 |
cellular response to stimulus
|
AKR1B1, AKR1C3, ALPL, AURKB, AXL, CA9, CYP1A1, CYP1A2, CYP1B1, ESR1, FABP4, FLT3, IGF1R, KDR, KIT, MIF, RORC, SRC |
3.06217 |
[BP] GO:0009892 |
negative regulation of metabolic process
|
ADORA1, AKR1C3, AURKB, CNR1, CNR2, CSNK2A1, ESR1, ESR2, ESRRA, FABP4, IGF1R, KDR, MET, MIF, MMP12, PPARA, RORC, SRC, XDH |
3.05699 |
[BP] GO:0043436 |
oxoacid metabolic process
|
AKR1C3, ALOX5, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, IDO1, MIF, PIM1, PPARA |
3.05699 |
[BP] GO:0006805 |
xenobiotic metabolic process
|
CYP1A1, CYP1A2, CYP1B1, CYP2A13, RORC |
3.05699 |
[BP] GO:0030540 |
female genitalia development
|
AXL, CYP19A1, ESR1 |
3.03138 |
[BP] GO:0030334 |
regulation of cell migration
|
ADORA1, ADORA3, CYP19A1, CYP1B1, IGF1R, KDR, KIT, MET, MIF, SRC |
3.02298 |
[BP] GO:0006352 |
DNA-templated transcription, initiation
|
ESR1, ESR2, ESRRA, ESRRB, PPARA, RORC |
3.02298 |
[BP] GO:0006082 |
organic acid metabolic process
|
AKR1C3, ALOX5, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, IDO1, MIF, PIM1, PPARA |
2.99971 |
[BP] GO:0031347 |
regulation of defense response
|
ADORA1, CNR1, CNR2, CYP19A1, ESR1, FABP4, IDO1, MMP12, PPARA, SRC |
2.96395 |
[BP] GO:0051896 |
regulation of protein kinase B signaling
|
AKR1C3, AXL, KIT, MET, SRC, XDH |
2.96395 |
[BP] GO:0071704 |
organic substance metabolic process
|
ACHE, ADORA1, AKR1B1, AKR1C3, ALOX5, ALPL, AOX1, AURKB, AXL, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, ESR1, ESR2, ESRRA, ESRRB, FABP4, FLT3, HSD17B1, IDO1, IGF1R, KDR, KIT, MET, MIF, MMP12, PIM1, PPARA, RORC, SRC, XDH |
2.8434 |
[BP] GO:0042446 |
hormone biosynthetic process
|
AKR1B1, AKR1C3, CYP19A1, HSD17B1 |
2.81315 |
[BP] GO:2000145 |
regulation of cell motility
|
ADORA1, ADORA3, CYP19A1, CYP1B1, IGF1R, KDR, KIT, MET, MIF, SRC |
2.81315 |
[BP] GO:0048585 |
negative regulation of response to stimulus
|
ADORA1, CNR1, CNR2, CYP19A1, ESR1, ESR2, IGF1R, MET, MIF, MMP12, PPARA, SRC, XDH |
2.70449 |
[BP] GO:0046110 |
None
|
AOX1, XDH |
2.67382 |
[BP] GO:0030520 |
intracellular estrogen receptor signaling pathway
|
ESR1, ESR2, SRC |
2.6545 |
[BP] GO:0042180 |
None
|
AKR1B1, AKR1C3, CYP19A1, IDO1 |
2.6247 |
[BP] GO:0019222 |
regulation of metabolic process
|
ACHE, ADORA1, ADORA3, AKR1C3, AURKB, CA9, CNR1, CNR2, CSNK2A1, CYP1A1, CYP1A2, CYP1B1, ESR1, ESR2, ESRRA, ESRRB, FABP4, FLT3, IGF1R, KDR, KIT, MET, MIF, MMP12, PIM1, PPARA, RORC, SRC, XDH |
2.61823 |
[BP] GO:0009404 |
toxin metabolic process
|
CYP1A1, CYP1A2, CYP1B1 |
2.60302 |
[BP] GO:0044248 |
cellular catabolic process
|
ACHE, AKR1C3, AOX1, AURKB, CSNK2A1, CYP1A1, CYP1A2, CYP1B1, CYP2A6, FABP4, IDO1, SRC, XDH |
2.5767 |
[BP] GO:0008210 |
estrogen metabolic process
|
CYP19A1, CYP1B1, HSD17B1 |
2.55488 |
[BP] GO:1903409 |
reactive oxygen species biosynthetic process
|
CYP1A1, CYP1A2, CYP1B1 |
2.55488 |
[BP] GO:0040012 |
regulation of locomotion
|
ADORA1, ADORA3, CYP19A1, CYP1B1, IGF1R, KDR, KIT, MET, MIF, SRC |
2.55488 |
[BP] GO:0051270 |
regulation of cellular component movement
|
ADORA1, ADORA3, CYP19A1, CYP1B1, IGF1R, KDR, KIT, MET, MIF, SRC |
2.54507 |
[BP] GO:1901575 |
None
|
ACHE, ADORA1, AKR1C3, AOX1, AURKB, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A6, FABP4, IDO1, XDH |
2.53917 |
[BP] GO:0051897 |
positive regulation of protein kinase B signaling
|
AKR1C3, AXL, KIT, MET, SRC |
2.53917 |
[BP] GO:0032879 |
regulation of localization
|
ACHE, ADORA1, ADORA3, AXL, CA7, CNR1, CSNK2A1, CYP19A1, CYP1B1, IGF1R, KDR, KIT, MET, MIF, MMP12, PPARA, SRC |
2.50578 |
[BP] GO:0051173 |
positive regulation of nitrogen compound metabolic process
|
ADORA1, AURKB, CSNK2A1, ESR1, ESR2, ESRRA, ESRRB, FLT3, IGF1R, KDR, KIT, MET, MIF, MMP12, PPARA, RORC, SRC, XDH |
2.50447 |
[BP] GO:0046427 |
positive regulation of JAK-STAT cascade
|
AKR1B1, CYP1B1, FLT3, KIT |
2.46944 |
[BP] GO:0008610 |
lipid biosynthetic process
|
ACHE, AKR1B1, AKR1C3, CSNK2A1, CYP19A1, CYP1A1, HSD17B1, MIF |
2.46944 |
[BP] GO:0048608 |
reproductive structure development
|
AKR1C3, AXL, CYP19A1, ESR1, KIT, SRC |
2.44125 |
[BP] GO:0016042 |
lipid catabolic process
|
ADORA1, AKR1C3, CYP19A1, CYP1A2, CYP1B1, FABP4 |
2.44125 |
[BP] GO:0022414 |
reproductive process
|
AKR1B1, AKR1C3, ALPL, AXL, CNR1, CYP19A1, CYP1A1, ESR1, ESRRB, IDO1, KIT, SRC |
2.44125 |
[BP] GO:1904894 |
positive regulation of STAT cascade
|
AKR1B1, CYP1B1, FLT3, KIT |
2.44076 |
[BP] GO:0042493 |
response to drug
|
AKR1B1, AXL, CA9, CNR1, CNR2, CYP1A1, CYP1B1, KDR, SRC |
2.44076 |
[BP] GO:0006145 |
None
|
AOX1, XDH |
2.44076 |
[BP] GO:0038171 |
None
|
CNR1, CNR2 |
2.44076 |
[BP] GO:0018894 |
dibenzo-p-dioxin metabolic process
|
CYP1A1, CYP1A2 |
2.44076 |
[BP] GO:0009893 |
positive regulation of metabolic process
|
ADORA1, AKR1C3, AURKB, CSNK2A1, ESR1, ESR2, ESRRA, ESRRB, FLT3, IGF1R, KDR, KIT, MET, MIF, MMP12, PPARA, RORC, SRC, XDH |
2.43723 |
[BP] GO:0006468 |
protein phosphorylation
|
AURKB, AXL, CSNK2A1, FLT3, IGF1R, KDR, KIT, MET, PIM1, SRC |
2.41453 |
[BP] GO:2000106 |
regulation of leukocyte apoptotic process
|
AURKB, AXL, IDO1, MIF |
2.3939 |
[BP] GO:0032103 |
positive regulation of response to external stimulus
|
CNR1, FABP4, IDO1, KDR, MET, MIF |
2.38757 |
[BP] GO:0070229 |
negative regulation of lymphocyte apoptotic process
|
AURKB, IDO1, MIF |
2.35785 |
[BP] GO:0031348 |
negative regulation of defense response
|
ADORA1, CNR2, CYP19A1, MMP12, PPARA |
2.34215 |
[BP] GO:0009605 |
response to external stimulus
|
ADORA1, AKR1C3, ALPL, AXL, CNR1, CNR2, CYP1A1, CYP1A2, IDO1, KIT, MMP12, SRC |
2.33689 |
[BP] GO:0031325 |
positive regulation of cellular metabolic process
|
ADORA1, AKR1C3, AURKB, ESR1, ESR2, ESRRA, ESRRB, FLT3, IGF1R, KDR, KIT, MET, MIF, MMP12, PPARA, RORC, SRC, XDH |
2.3286 |
[BP] GO:0065009 |
regulation of molecular function
|
ADORA1, ADORA3, AURKB, CNR1, CNR2, CSNK2A1, CYP1B1, ESR1, ESR2, FABP4, FLT3, IGF1R, KIT, MET, MIF, PIM1, PPARA, SRC, XDH |
2.3286 |
[BP] GO:0050731 |
positive regulation of peptidyl-tyrosine phosphorylation
|
ADORA1, FLT3, KIT, MIF, SRC |
2.32757 |
[BP] GO:0043552 |
positive regulation of phosphatidylinositol 3-kinase activity
|
FLT3, KIT, SRC |
2.32708 |
[BP] GO:0000302 |
response to reactive oxygen species
|
AKR1B1, AKR1C3, AXL, CYP1B1, SRC |
2.32032 |
[BP] GO:0010604 |
positive regulation of macromolecule metabolic process
|
ADORA1, AURKB, CSNK2A1, ESR1, ESR2, ESRRA, ESRRB, FLT3, IGF1R, KDR, KIT, MET, MIF, MMP12, PPARA, RORC, SRC, XDH |
2.30828 |
[BP] GO:0003006 |
developmental process involved in reproduction
|
AKR1C3, ALPL, AXL, CYP19A1, ESR1, ESRRB, KIT, SRC |
2.27434 |
[BP] GO:0009966 |
regulation of signal transduction
|
ADORA1, AKR1B1, AKR1C3, AURKB, AXL, CSNK2A1, CYP1B1, ESR1, ESR2, FLT3, IGF1R, KDR, KIT, MET, MIF, MMP12, SRC, XDH |
2.26474 |
[BP] GO:0044283 |
None
|
AKR1B1, AKR1C3, ALOX5, CYP19A1, CYP1A1, IDO1, MIF |
2.26474 |
[BP] GO:0061370 |
testosterone biosynthetic process
|
AKR1C3, CYP19A1 |
2.26454 |
[BP] GO:0002318 |
myeloid progenitor cell differentiation
|
FLT3, KIT |
2.26454 |
[BP] GO:0050804 |
modulation of chemical synaptic transmission
|
ACHE, ADORA1, CA7, CNR1, CNR2, KIT |
2.24343 |
[BP] GO:0099177 |
regulation of trans-synaptic signaling
|
ACHE, ADORA1, CA7, CNR1, CNR2, KIT |
2.24343 |
[BP] GO:0090218 |
positive regulation of lipid kinase activity
|
FLT3, KIT, SRC |
2.23244 |
[BP] GO:0010907 |
None
|
ESRRB, PPARA, SRC |
2.23244 |
[BP] GO:1901361 |
None
|
AOX1, CYP19A1, CYP1A1, CYP1A2, CYP2A6, IDO1, XDH |
2.1949 |
[BP] GO:0043207 |
response to external biotic stimulus
|
ALPL, AXL, CNR1, CNR2, CYP1A1, CYP1A2, IDO1, MMP12, SRC |
2.19002 |
[BP] GO:0010906 |
None
|
ESRRB, PPARA, RORC, SRC |
2.18464 |
[BP] GO:0007165 |
signal transduction
|
ADORA1, ADORA3, AKR1B1, AKR1C3, AXL, CNR1, CNR2, CSNK2A1, CYP1B1, ESR1, ESR2, ESRRA, ESRRB, FLT3, IGF1R, KDR, KIT, MET, MIF, PIM1, PPARA, RORC, SRC |
2.17492 |
[BP] GO:0034599 |
cellular response to oxidative stress
|
AKR1B1, AKR1C3, AXL, CYP1B1, SRC |
2.13946 |
[BP] GO:0051239 |
regulation of multicellular organismal process
|
ADORA1, ADORA3, AXL, CNR1, CYP1B1, ESR1, ESRRA, ESRRB, IDO1, KDR, KIT, MET, MIF, MMP12, PIM1, SRC, XDH |
2.13946 |
[BP] GO:0010760 |
negative regulation of macrophage chemotaxis
|
CYP19A1, MIF |
2.12572 |
[BP] GO:0046113 |
None
|
AOX1, XDH |
2.12572 |
[BP] GO:0032229 |
None
|
ADORA1, CNR2 |
2.12572 |
[BP] GO:0060135 |
None
|
AKR1B1, CNR1, ESR1 |
2.10702 |
[BP] GO:0032844 |
regulation of homeostatic process
|
ADORA1, AURKB, CA7, CNR1, KDR, MIF, SRC |
2.09686 |
[BP] GO:0048806 |
genitalia development
|
AXL, CYP19A1, ESR1 |
2.07811 |
[BP] GO:0002686 |
None
|
ADORA1, CYP19A1, MIF |
2.07811 |
[BP] GO:0009607 |
response to biotic stimulus
|
ALPL, AXL, CNR1, CNR2, CYP1A1, CYP1A2, IDO1, MMP12, SRC |
2.07564 |
[BP] GO:0010648 |
negative regulation of cell communication
|
ACHE, ADORA1, CNR2, ESR1, ESR2, IGF1R, MET, MIF, MMP12, SRC, XDH |
2.05621 |
[BP] GO:0002682 |
regulation of immune system process
|
ADORA1, AXL, CNR1, CNR2, CYP19A1, ESR1, ESRRA, IDO1, KIT, MIF, MMP12, SRC |
2.04809 |
[BP] GO:0023057 |
negative regulation of signaling
|
ACHE, ADORA1, CNR2, ESR1, ESR2, IGF1R, MET, MIF, MMP12, SRC, XDH |
2.04809 |
[BP] GO:0051240 |
positive regulation of multicellular organismal process
|
AXL, CNR1, CYP1B1, ESRRB, IDO1, KDR, KIT, MET, MIF, MMP12, PIM1, SRC |
2.03597 |
[BP] GO:0006721 |
terpenoid metabolic process
|
AKR1C3, CYP1A1, CYP1A2, CYP1B1 |
2.03597 |
[BP] GO:0006091 |
generation of precursor metabolites and energy
|
AKR1B1, AOX1, CYP19A1, CYP1A2, IDO1, XDH |
2.03392 |
[BP] GO:0042542 |
response to hydrogen peroxide
|
AKR1B1, AXL, CYP1B1, SRC |
2.02616 |
[BP] GO:0008406 |
gonad development
|
AKR1C3, CYP19A1, ESR1, KIT |
2.02616 |
[BP] GO:0043405 |
regulation of MAP kinase activity
|
ADORA1, FLT3, IGF1R, KIT, MIF, SRC |
2.01593 |
[BP] GO:0051001 |
None
|
CNR1, CNR2 |
2.01593 |
[BP] GO:0031324 |
negative regulation of cellular metabolic process
|
AKR1C3, AURKB, CNR1, CSNK2A1, ESR1, ESR2, ESRRA, FABP4, IGF1R, MET, MIF, MMP12, PPARA, RORC, SRC, XDH |
2.00234 |
[CC] GO:0005886 |
plasma membrane
|
ACHE, ADORA1, ADORA3, ALPL, AXL, CA12, CA14, CA4, CA9, CNR1, CNR2, CSNK2A1, ESR1, FLT3, IGF1R, KDR, KIT, MET, PIM1, SRC |
1.35825 |
[CC] GO:0042629 |
None
|
AKR1B1, KIT |
1.21576 |
[CC] GO:0031226 |
intrinsic component of plasma membrane
|
ADORA1, ADORA3, AXL, CA4, CNR1, CNR2, FLT3, IGF1R, KDR, MET |
1.18633 |
[CC] GO:0044228 |
host cell surface
|
AXL |
1.03795 |
[CC] GO:0044464 |
cell part
|
ACHE, ADORA1, ADORA3, AKR1B1, AKR1C3, ALOX5, ALPL, AOX1, AURKB, AXL, CA12, CA14, CA4, CA7, CA9, CNR1, CNR2, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, ESR1, ESR2, ESRRA, ESRRB, FABP4, FLT3, HSD17B1, IDO1, IGF1R, KDR, KIT, MET, MIF, MMP12, PIM1, PPARA, RORC, SRC, XDH |
0.935402 |
[MF] GO:0046914 |
transition metal ion binding
|
ALOX5, AOX1, CA12, CA4, CA7, CA9, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, ESR1, ESR2, ESRRA, ESRRB, MMP12, PIM1, PPARA, RORC, XDH |
10.609 |
[MF] GO:0043167 |
ion binding
|
ACHE, ALOX5, ALPL, AOX1, AURKB, AXL, CA12, CA14, CA4, CA7, CA9, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, ESR1, ESR2, ESRRA, ESRRB, FABP4, FLT3, HSD17B1, IDO1, IGF1R, KDR, KIT, MET, MMP12, PIM1, PPARA, RORC, SRC, XDH |
7.69868 |
[MF] GO:0016712 |
oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen
|
CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6 |
7.15598 |
[MF] GO:0005506 |
iron ion binding
|
ALOX5, AOX1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, XDH |
6.89337 |
[MF] GO:0004089 |
carbonate dehydratase activity
|
CA12, CA14, CA4, CA7, CA9 |
6.70448 |
[MF] GO:0020037 |
heme binding
|
CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, IDO1, SRC |
6.28685 |
[MF] GO:0003824 |
catalytic activity
|
ACHE, ADORA1, AKR1B1, AKR1C3, ALOX5, ALPL, AOX1, AURKB, AXL, CA12, CA14, CA4, CA7, CA9, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, FLT3, HSD17B1, IDO1, IGF1R, KDR, KIT, MET, MIF, MMP12, PIM1, SRC, XDH |
6.07973 |
[MF] GO:0046906 |
tetrapyrrole binding
|
CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, IDO1, SRC |
6.07973 |
[MF] GO:0098531 |
transcription factor activity, direct ligand regulated sequence-specific DNA binding
|
ESR1, ESR2, ESRRA, ESRRB, PPARA, RORC |
5.94209 |
[MF] GO:0004879 |
nuclear receptor activity
|
ESR1, ESR2, ESRRA, ESRRB, PPARA, RORC |
5.94209 |
[MF] GO:0070330 |
aromatase activity
|
CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13 |
5.86792 |
[MF] GO:0004497 |
monooxygenase activity
|
AKR1C3, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6 |
5.86257 |
[MF] GO:0003707 |
steroid hormone receptor activity
|
ESR1, ESR2, ESRRA, ESRRB, PPARA, RORC |
5.59898 |
[MF] GO:0016491 |
oxidoreductase activity
|
AKR1B1, AKR1C3, ALOX5, AOX1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, HSD17B1, IDO1, XDH |
5.59898 |
[MF] GO:0004714 |
transmembrane receptor protein tyrosine kinase activity
|
AXL, FLT3, IGF1R, KDR, KIT, MET |
5.53016 |
[MF] GO:0048037 |
cofactor binding
|
AOX1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, HSD17B1, IDO1, SRC, XDH |
5.44321 |
[MF] GO:0043169 |
cation binding
|
ACHE, ALOX5, ALPL, AOX1, AURKB, CA12, CA14, CA4, CA7, CA9, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, ESR1, ESR2, ESRRA, ESRRB, IDO1, KIT, MMP12, PIM1, PPARA, RORC, XDH |
5.33849 |
[MF] GO:0008144 |
drug binding
|
ACHE, AURKB, AXL, CNR1, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, FLT3, IGF1R, KDR, KIT, MET, PIM1, PPARA, SRC |
5.33115 |
[MF] GO:0038023 |
signaling receptor activity
|
ADORA1, ADORA3, AXL, CNR1, CNR2, ESR1, ESR2, ESRRA, ESRRB, FLT3, IGF1R, KDR, KIT, MET, PPARA, RORC |
5.12745 |
[MF] GO:0019199 |
transmembrane receptor protein kinase activity
|
AXL, FLT3, IGF1R, KDR, KIT, MET |
5.05895 |
[MF] GO:0046872 |
metal ion binding
|
ALOX5, ALPL, AOX1, AURKB, CA12, CA14, CA4, CA7, CA9, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, ESR1, ESR2, ESRRA, ESRRB, IDO1, KIT, MMP12, PIM1, PPARA, RORC, XDH |
4.91595 |
[MF] GO:0005496 |
steroid binding
|
ESR1, ESR2, ESRRA, ESRRB, HSD17B1, RORC |
4.86788 |
[MF] GO:0016705 |
oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen
|
AKR1C3, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6 |
4.76541 |
[MF] GO:0019825 |
oxygen binding
|
CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13 |
4.75563 |
[MF] GO:0004872 |
receptor activity
|
ADORA1, ADORA3, AXL, CNR1, CNR2, ESR1, ESR2, ESRRA, ESRRB, FLT3, IGF1R, KDR, KIT, MET, PPARA, RORC |
4.53319 |
[MF] GO:0009055 |
electron transfer activity
|
AKR1B1, AOX1, CYP19A1, CYP1A2, IDO1, XDH |
4.40948 |
[MF] GO:0004713 |
protein tyrosine kinase activity
|
AXL, FLT3, IGF1R, KDR, KIT, MET, SRC |
4.40948 |
[MF] GO:0016836 |
hydro-lyase activity
|
CA12, CA14, CA4, CA7, CA9 |
4.40948 |
[MF] GO:0060089 |
molecular transducer activity
|
ADORA1, ADORA3, AXL, CNR1, CNR2, ESR1, ESR2, ESRRA, ESRRB, FLT3, IGF1R, KDR, KIT, MET, PPARA, RORC |
4.39544 |
[MF] GO:0004871 |
signal transducer activity
|
ADORA1, ADORA3, AXL, CNR1, CNR2, ESR1, ESR2, ESRRA, ESRRB, FLT3, IGF1R, KDR, KIT, MET, PPARA, RORC |
4.076 |
[MF] GO:0016835 |
carbon-oxygen lyase activity
|
CA12, CA14, CA4, CA7, CA9 |
3.81936 |
[MF] GO:0008395 |
steroid hydroxylase activity
|
CYP19A1, CYP1A1, CYP2A13, CYP2A6 |
3.6931 |
[MF] GO:0008270 |
zinc ion binding
|
CA12, CA4, CA7, CA9, ESR1, ESR2, ESRRA, ESRRB, MMP12, PPARA, RORC |
3.61911 |
[MF] GO:0004672 |
protein kinase activity
|
AURKB, AXL, CSNK2A1, FLT3, IGF1R, KDR, KIT, MET, PIM1, SRC |
3.58085 |
[MF] GO:0016903 |
None
|
AKR1B1, AKR1C3, AOX1, XDH |
3.30123 |
[MF] GO:0038052 |
RNA polymerase II transcription factor activity, estrogen-activated sequence-specific DNA binding
|
ESR1, ESR2 |
3.08094 |
[MF] GO:0008389 |
None
|
CYP2A13, CYP2A6 |
3.08094 |
[MF] GO:0016773 |
phosphotransferase activity, alcohol group as acceptor
|
AURKB, AXL, CSNK2A1, FLT3, IGF1R, KDR, KIT, MET, PIM1, SRC |
2.97278 |
[MF] GO:1901363 |
heterocyclic compound binding
|
ADORA1, AOX1, AURKB, AXL, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, ESR1, ESR2, ESRRA, ESRRB, FLT3, HSD17B1, IDO1, IGF1R, KDR, KIT, MET, MMP12, PIM1, PPARA, RORC, SRC, XDH |
2.9442 |
[MF] GO:0044877 |
macromolecular complex binding
|
ACHE, ADORA1, CSNK2A1, ESRRB, FLT3, IGF1R, KDR, MMP12, PIM1, PPARA, SRC |
2.92264 |
[MF] GO:0097159 |
organic cyclic compound binding
|
ADORA1, AOX1, AURKB, AXL, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, ESR1, ESR2, ESRRA, ESRRB, FLT3, HSD17B1, IDO1, IGF1R, KDR, KIT, MET, MMP12, PIM1, PPARA, RORC, SRC, XDH |
2.87799 |
[MF] GO:0016614 |
oxidoreductase activity, acting on CH-OH group of donors
|
AKR1B1, AKR1C3, AOX1, HSD17B1, XDH |
2.72727 |
[MF] GO:0016301 |
kinase activity
|
AURKB, AXL, CSNK2A1, FLT3, IGF1R, KDR, KIT, MET, PIM1, SRC |
2.67382 |
[MF] GO:0004949 |
None
|
CNR1, CNR2 |
2.67382 |
[MF] GO:0008289 |
lipid binding
|
AXL, ESR1, ESR2, ESRRA, ESRRB, FABP4, HSD17B1, PPARA, RORC |
2.67205 |
[MF] GO:0034056 |
estrogen response element binding
|
ESR1, ESR2 |
2.44076 |
[MF] GO:0030284 |
estrogen receptor activity
|
ESR1, ESR2 |
2.26454 |
[MF] GO:0032403 |
protein complex binding
|
ACHE, ADORA1, ESRRB, FLT3, IGF1R, KDR, MMP12, PPARA, SRC |
2.23978 |
[MF] GO:0016829 |
lyase activity
|
CA12, CA14, CA4, CA7, CA9 |
2.23244 |
[MF] GO:0016772 |
transferase activity, transferring phosphorus-containing groups
|
AURKB, AXL, CSNK2A1, FLT3, IGF1R, KDR, KIT, MET, PIM1, SRC |
2.19002 |
[MF] GO:0043546 |
None
|
AOX1, XDH |
2.12572 |
[MF] GO:0005021 |
vascular endothelial growth factor-activated receptor activity
|
FLT3, KDR |
2.01593 |
[MF] GO:0004032 |
None
|
AKR1B1, AKR1C3 |
2.01593 |
[MF] GO:0001609 |
None
|
ADORA1, ADORA3 |
2.01593 |