Description of the Component
Component ID |
TCMH562 |
Latin Name |
Saposhnikovia divaricata |
English Name |
Divaricate saposhnikovia |
Chinese Pinyin Name |
Fang Feng |
中文名 |
防风 |
TCM Properties |
Minor Warm,Pungent,Sweet |
TCM Meridians |
Bladder,Spleen,Liver |
Therapeutic Class English |
For relieving exterior syndrome |
Therapeutic Class Chinese |
解表 |
Functions |
induce diaphoresis, dispel wind, alleviate rheumatic conditions, and relieve spasm |
Toxicity |
NA |
Geo-authentic habitats (道地产区) |
Heilongjiang Province |
Reference |
Chinese Pharmacopoeia (2015) |
Barcode ID |
ITSAE3225-14 |
Barcode Source |
BOLDSYSTEMS |
TCM Prescriptions with the Component
| Prescription ID | Prescription English Name | Prescription Chinese Name |
|---|
Targeted Human Proteins by the Ingredient of Component
| Target ID | Gene Symbol | Target Name | Target Class | Uniprot ID |
|---|---|---|---|---|
| TCMT1 | EHMT2 | Histone-lysine N-methyltransferase, H3 lysine-9 specific 3 | Transferase | Q96KQ7 |
| TCMT101 | PTPN1 | Protein-tyrosine phosphatase 1B | Hydrolase | P18031 |
| TCMT11 | HIF1A | Hypoxia-inducible factor 1 alpha | Transcription factor | Q16665 |
| TCMT112 | ADORA3 | Adenosine A3 receptor | GPCR | P0DMS8 |
| TCMT125 | GBA | Beta-glucocerebrosidase | Hydrolase | P04062 |
| TCMT130 | ALOX5 | Arachidonate 5-lipoxygenase | Oxidoreductase | P09917 |
| TCMT131 | ACHE | Acetylcholinesterase | Hydrolase | P22303 |
| TCMT133 | CA1 | Carbonic anhydrase I | Lyase | P00915 |
| TCMT134 | CA2 | Carbonic anhydrase II | Lyase | P00918 |
| TCMT136 | CA12 | Carbonic anhydrase XII | Lyase | O43570 |
| TCMT137 | CA9 | Carbonic anhydrase IX | Lyase | Q16790 |
| TCMT138 | CA7 | Carbonic anhydrase VII | Lyase | P43166 |
| TCMT150 | RORC | Nuclear receptor ROR-gamma | Nuclear receptor | P51449 |
| TCMT156 | CYP19A1 | Cytochrome P450 19A1 | Oxidoreductase | P11511 |
| TCMT160 | HTR7 | Serotonin 7 (5-HT7) receptor | GPCR | P34969 |
| TCMT162 | UGT1A1 | UDP-glucuronosyltransferase 1-1 | Transferase | P22309 |
| TCMT17 | POLB | DNA polymerase beta | Transferase | P06746 |
| TCMT18 | GAA | Lysosomal alpha-glucosidase | Hydrolase | P10253 |
| TCMT186 | MAOB | Monoamine oxidase B | Oxidoreductase | P27338 |
| TCMT189 | DUSP3 | Dual specificity protein phosphatase 3 | Hydrolase | P51452 |
| TCMT193 | RELA | Nuclear factor NF-kappa-B p65 subunit | Transcription factor | Q04206 |
| TCMT2 | MAPT | Microtubule-associated protein tau | Unclassified | P10636 |
| TCMT206 | CYP2A6 | Cytochrome P450 2A6 | Oxidoreductase | P11509 |
| TCMT207 | BACE1 | Beta-secretase 1 | Protease | P56817 |
| TCMT208 | MAOA | Monoamine oxidase A | Oxidoreductase | P21397 |
| TCMT223 | AKR1B1 | Aldose reductase | Oxidoreductase | P15121 |
| TCMT225 | CA13 | Carbonic anhydrase XIII | Lyase | Q8N1Q1 |
| TCMT232 | ABCB1 | P-glycoprotein 1 | Transporter | P08183 |
| TCMT268 | CYP2A13 | Cytochrome P450 2A13 | Oxidoreductase | Q16696 |
| TCMT276 | SLCO2B1 | Solute carrier organic anion transporter family member 2B1 | Transporter | O94956 |
| TCMT277 | SLCO1B3 | Solute carrier organic anion transporter family member 1B3 | Transporter | Q9NPD5 |
| TCMT278 | SLCO1B1 | Solute carrier organic anion transporter family member 1B1 | Transporter | Q9Y6L6 |
| TCMT281 | DPP4 | Dipeptidyl peptidase IV | Unclassified | P27487 |
| TCMT296 | ADORA1 | Adenosine A1 receptor | GPCR | P30542 |
| TCMT30 | PTGS2 | Cyclooxygenase-2 | Oxidoreductase | P35354 |
| TCMT31 | CYP2C19 | Cytochrome P450 2C19 | Oxidoreductase | P33261 |
| TCMT33 | CYP3A4 | Cytochrome P450 3A4 | Oxidoreductase | P08684 |
| TCMT34 | CYP2D6 | Cytochrome P450 2D6 | Oxidoreductase | P10635 |
| TCMT41 | IDH1 | Isocitrate dehydrogenase [NADP] cytoplasmic | Oxidoreductase | O75874 |
| TCMT423 | EGFR | Epidermal growth factor receptor erbB1 | Kinase | P00533 |
| TCMT559 | ADRB2 | Beta-2 adrenergic receptor | GPCR | P07550 |
| TCMT571 | ADORA2B | Adenosine A2b receptor | GPCR | P29275 |
| TCMT597 | SLC28A3 | Solute carrier family 28 member 3 | Transporter | Q9HAS3 |
| TCMT6 | NFKB1 | Nuclear factor NF-kappa-B p105 subunit | Transcription factor | P19838 |
| TCMT620 | HSPA8 | Heat shock cognate 71 kDa protein | Unclassified | P11142 |
| TCMT632 | PNP | Purine nucleoside phosphorylase | Transferase | P00491 |
| TCMT704 | ERBB2 | Receptor protein-tyrosine kinase erbB-2 | Kinase | P04626 |
| TCMT707 | ADORA2A | Adenosine A2a receptor | GPCR | P29274 |
| TCMT709 | SLC28A2 | Sodium/nucleoside cotransporter 2 | Transporter | O43868 |
| TCMT710 | SLC28A1 | Sodium/nucleoside cotransporter 1 | Transporter | O00337 |
| TCMT8 | KDM4E | Lysine-specific demethylase 4D-like | Oxidoreductase | B2RXH2 |
| TCMT80 | MAPK1 | MAP kinase ERK2 | Kinase | P28482 |
| TCMT82 | ESR1 | Estrogen receptor alpha | Nuclear receptor | P03372 |
| TCMT87 | CYP2C9 | Cytochrome P450 2C9 | Oxidoreductase | P11712 |
Targeted Pathogenic Microbes by the Ingredient of Component
| Target ID | Target Name |
|---|---|
| TCMT1104 | Sortase |
| TCMT1112 | Quinolone resistance protein norA |
| TCMT1218 | Staphylococcus aureus |
| TCMT1232 | Pseudomonas aeruginosa |
| TCMT1246 | Escherichia coli |
| TCMT1251 | Candida albicans |
| TCMT1349 | Helicobacter pylori SS1 |
| TCMT1438 | Plasmodium falciparum |
| TCMT1454 | Bacillus subtilis |
| TCMT1455 | Mycobacterium tuberculosis H37Rv |
| TCMT1463 | Mycobacterium tuberculosis |
| TCMT1464 | Hepatitis B virus |
| TCMT1465 | Entamoeba histolytica |
Ingredient Structrues
Ingredient ID: TCMC995
Formula: C35H60O6
Ingredient ID: TCMC906
Formula: C9H6O2
Ingredient ID: TCMC801
Formula: C29H50O
Ingredient ID: TCMC787
Formula: C12H8O4
Ingredient ID: TCMC7012
Formula: C17H24O2
Ingredient ID: TCMC6952
Formula: C8H16O
Ingredient ID: TCMC6527
Formula: C22H28O10
Ingredient ID: TCMC65
Formula: C14H14O4
Ingredient ID: TCMC632
Formula: C10H13N5O4
Ingredient ID: TCMC554
Formula: C6H9NS
Ingredient ID: TCMC5460
Formula: C19H20O6
Ingredient ID: TCMC5325
Formula: C15H24
Ingredient ID: TCMC5270
Formula: C17H18O7
Ingredient ID: TCMC4689
Formula: C20H22O7
Ingredient ID: TCMC4466
Formula: C17H18O6
Ingredient ID: TCMC4158
Formula: C19H20O5
Ingredient ID: TCMC3966
Formula: C29H50O
Ingredient ID: TCMC3867
Formula: C16H18O5
Ingredient ID: TCMC3825
Formula: C10H16
Ingredient ID: TCMC3621
Formula: C15H16O5
Ingredient ID: TCMC344
Formula: C19H20O5
Ingredient ID: TCMC3310
Formula: C15H26O
Ingredient ID: TCMC3299
Formula: C15H22
Ingredient ID: TCMC3032
Formula: C24H48O2
Ingredient ID: TCMC2970
Formula: C5H10O
Ingredient ID: TCMC2890
Formula: C6H12O
Ingredient ID: TCMC289
Formula: C5H12O
Ingredient ID: TCMC2886
Formula: C12H22O11
Ingredient ID: TCMC2843
Formula: C8H16O
Ingredient ID: TCMC274
Formula: C6H14O
Ingredient ID: TCMC2482
Formula: C17H24O
Ingredient ID: TCMC2381
Formula: C8H10O
Ingredient ID: TCMC2237
Formula: C16H12O5
Ingredient ID: TCMC220
Formula: C24H26O7
Ingredient ID: TCMC215
Formula: C24H26O7
Ingredient ID: TCMC2138
Formula: C16H12O4
Ingredient ID: TCMC2051
Formula: C10H8O4
Ingredient ID: TCMC1961
Formula: C11H6O3
Ingredient ID: TCMC1866
Formula: C17H16O5
Ingredient ID: TCMC1858
Formula: C16H14O4
Ingredient ID: TCMC1854
Formula: C5H10O
Ingredient ID: TCMC1750
Formula: C20H24O9
Ingredient ID: TCMC1551
Formula: C12H8O4
Ingredient ID: TCMC1404
Formula: C13H10O5
Ingredient ID: TCMC1395
Formula: C16H14O4
Ingredient ID: TCMC1382
Formula: C12H8O4
Ingredient ID: TCMC1189
Formula: C11H10O5
Properties
| Ingredient ID | Formulae | Name | MW | AlogP | MlogP | XlogP | # HBA | # HBD | PSA | # Rotatable Bond | # Ring | # Heacy Atom | Lipinski RO5 Violation |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| TCMC65 | C14H14O4 | (2R)-2-(2-Hydroxypropan-2-Yl)-2,3-Dihydrofuro[3,2-G]Chromen-7-One | 246.09 | 0.2617 | 2.56 | 2.093 | 2 | 1 | 55.76 | 4 | 3 | 18 | 0 |
| TCMC215 | C24H26O7 | [(9R,10R)-8,8-Dimethyl-9-[(Z)-2-Methylbut-2-Enoyl]Oxy-2-Oxo-9,10-Dihydropyrano[2,3-F]Chromen-10-Yl] (Z)-2-Methylbut-2-Enoate | 426.17 | 3.1344 | 3.33 | 4.537 | 5 | 0 | 88.13 | 12 | 3 | 31 | 0 |
| TCMC220 | C24H26O7 | [8,8-Dimethyl-9-[(Z)-2-Methylbut-2-Enoyl]Oxy-2-Oxo-9,10-Dihydropyrano[2,3-F]Chromen-10-Yl] (Z)-2-Methylbut-2-Enoate | 426.17 | 3.1344 | 3.33 | 4.537 | 5 | 0 | 88.13 | 12 | 3 | 31 | 0 |
| TCMC274 | C6H14O | 1-Hexanol | 102.1 | -1.5494 | 2.01 | 1.989 | 1 | 1 | 20.23 | 6 | 0 | 7 | 0 |
| TCMC289 | C5H12O | 1-Pentanol | 88.09 | -1.2614 | 1.9 | 1.42 | 1 | 1 | 20.23 | 5 | 0 | 6 | 0 |
| TCMC344 | C19H20O5 | 2-[(2S)-7-Oxo-2,3-Dihydrofuro[3,2-G]Chromen-2-Yl]Propan-2-Yl (E)-2-Methylbut-2-Enoate | 328.13 | 1.9846 | 3 | 3.83 | 3 | 0 | 61.83 | 8 | 3 | 24 | 0 |
| TCMC554 | C6H9NS | 5-Isothiocyanatopent-1-Ene | 127.05 | 0.7268 | 1.9 | 3.005 | 1 | 0 | 44.45 | 4 | 0 | 8 | 0 |
| TCMC632 | C10H13N5O4 | Adenosine | 267.1 | -2.2791 | 1.57 | -1.809 | 9 | 4 | 139.54 | 6 | 3 | 19 | 0 |
| TCMC787 | C12H8O4 | Bergapten | 216.04 | 0.0641 | 2.34 | 1.69 | 1 | 0 | 48.67 | 2 | 3 | 16 | 0 |
| TCMC801 | C29H50O | Beta-Sitosterol | 414.39 | 1.3 | 4.54 | 11.595 | 1 | 1 | 20.23 | 13 | 4 | 30 | 1 |
| TCMC906 | C9H6O2 | Chromone | 146.04 | -0.5778 | 2.23 | 2.318 | 1 | 0 | 26.3 | 0 | 2 | 11 | 0 |
| TCMC995 | C35H60O6 | Daucosterol | 576.44 | -0.4469 | 4.65 | 10.487 | 6 | 4 | 99.38 | 19 | 5 | 41 | 1 |
| TCMC1189 | C11H10O5 | Fraxidin | 222.05 | -0.2939 | 2.12 | 0.644 | 1 | 1 | 64.99 | 5 | 2 | 16 | 0 |
| TCMC1382 | C12H8O4 | Isobergaptene | 216.04 | 0.0641 | 2.34 | 1.69 | 1 | 0 | 48.67 | 2 | 3 | 16 | 0 |
| TCMC1395 | C16H14O4 | Isoimperatorin | 270.09 | 1.5296 | 2.78 | 2.891 | 1 | 0 | 48.67 | 5 | 3 | 20 | 0 |
| TCMC1404 | C13H10O5 | Isopimpinellin | 246.05 | 0.0123 | 2.34 | 1.246 | 1 | 0 | 57.9 | 4 | 3 | 18 | 0 |
| TCMC1551 | C12H8O4 | Methoxsalen | 216.04 | 0.0641 | 2.34 | 1.69 | 1 | 0 | 48.67 | 2 | 3 | 16 | 0 |
| TCMC1750 | C20H24O9 | Nodakenin | 408.14 | -1.4852 | 2.67 | 0.985 | 7 | 4 | 134.91 | 10 | 4 | 29 | 0 |
| TCMC1854 | C5H10O | Pentanal | 86.07 | -0.6823 | 1.9 | 1.725 | 1 | 0 | 17.07 | 4 | 0 | 6 | 0 |
| TCMC1858 | C16H14O4 | Pentosalen | 270.09 | 1.5296 | 2.78 | 2.891 | 1 | 0 | 48.67 | 5 | 3 | 20 | 0 |
| TCMC1866 | C17H16O5 | Phellopterin | 300.1 | 1.4778 | 2.78 | 2.447 | 1 | 0 | 57.9 | 7 | 3 | 22 | 0 |
| TCMC1961 | C11H6O3 | Psoralen | 186.03 | 0.1159 | 2.34 | 2.134 | 1 | 0 | 39.44 | 0 | 3 | 14 | 0 |
| TCMC2051 | C10H8O4 | Scopoletin | 192.04 | -0.2421 | 2.12 | 1.088 | 1 | 1 | 55.76 | 3 | 2 | 14 | 0 |
| TCMC2138 | C16H12O4 | Techtochrysin | 268.07 | -1.0157 | 2.78 | 3.682 | 1 | 1 | 55.76 | 4 | 3 | 20 | 0 |
| TCMC2237 | C16H12O5 | Wogonin | 284.07 | -1.476 | 2.67 | 2.719 | 1 | 2 | 75.99 | 5 | 3 | 21 | 0 |
| TCMC2381 | C8H10O | Phenylethyl Alcohol | 122.07 | -0.1931 | 2.23 | 3.189 | 1 | 1 | 20.23 | 3 | 1 | 9 | 0 |
| TCMC2482 | C17H24O | Falcarinol | 244.18 | 1.0335 | 3.22 | 6.197 | 1 | 1 | 20.23 | 10 | 0 | 18 | 1 |
| TCMC2843 | C8H16O | Octanal | 128.1201151 | -1.5463 | 2.23 | 3.432 | 1 | 0 | 17.07 | 6 | 0 | 9 | 0 |
| TCMC2886 | C12H22O11 | Sucrose | 342.1162115 | -4.3105 | 1.57 | -3.277 | 11 | 8 | 189.53 | 5 | 2 | 23 | 2 |
| TCMC2890 | C6H12O | Butylethylene Ether,Hexanal | 100.088815 | -0.9703 | 2.01 | 2.294 | 1 | 0 | 17.07 | 4 | 0 | 7 | 0 |
| TCMC2970 | C5H10O | 2-Methylbut-3-En-2-Ol | 86.07316494 | 0.8413 | 1.9 | 0.752 | 1 | 1 | 20.23 | 1 | 0 | 6 | 0 |
| TCMC3032 | C24H48O2 | Lignoceric Acid | 367.3576057 | -6.8795 | 3.88 | 11.641 | 2 | 0 | 40.13 | 22 | 0 | 26 | 2 |
| TCMC3299 | C15H22 | Cuparene | 202.1721507 | 1.6652 | 3.11 | 8.303 | 0 | 0 | 0 | 1 | 2 | 15 | 1 |
| TCMC3310 | C15H26O | Beta-Eudesmol | 222.1983655 | 0.6981 | 3 | 4.83 | 1 | 1 | 20.23 | 1 | 2 | 16 | 0 |
| TCMC3621 | C15H16O5 | 3'(S)-Hamaudol | 276.0997736 | -0.5953 | 2.56 | 0.537 | 2 | 2 | 66.76 | 0 | 3 | 20 | 0 |
| TCMC3825 | C10H16 | Α-Pinene | 136.1252005 | 1.5162 | 2.56 | 4.177 | 0 | 0 | 0 | 0 | 1 | 10 | 0 |
| TCMC3867 | C16H18O5 | 5-O-Methylvisamminol | 290.1154237 | 0.0682 | 2.67 | 1.08 | 5 | 1 | 55.76 | 2 | 3 | 21 | 0 |
| TCMC3966 | C29H50O | Sitosterol,Β-Sitosterol | 414.3861662 | 1.3 | 4.54 | 11.595 | 1 | 1 | 20.23 | 6 | 4 | 30 | 1 |
| TCMC4158 | C19H20O5 | Deltoin | 328.1310737 | 2.0524 | 3 | 4.354 | 3 | 0 | 52.6 | 4 | 3 | 24 | 0 |
| TCMC4466 | C17H18O6 | 3'-O-Acetylhamaudol | 318.1103383 | -0.2162 | 2.67 | 1.277 | 3 | 1 | 72.83 | 2 | 3 | 23 | 0 |
| TCMC4689 | C20H22O7 | Ledebouriellol | 374.136553 | 0.4556 | 2.89 | 1.237 | 4 | 2 | 93.06 | 4 | 3 | 27 | 0 |
| TCMC5270 | C17H18O7 | Divaricatol | 334.1052529 | -0.8882 | 2.56 | 0.24 | 4 | 2 | 93.06 | 3 | 3 | 24 | 0 |
| TCMC5325 | C15H24 | (S)-1-Methyl-4-(6-Methylhepta-1,5-Dien-2-Yl)Cyclohex-1-Ene,Β-Bisabolene | 204.1878008 | 3.3746 | 3.11 | 5.551 | 0 | 0 | 0 | 4 | 1 | 15 | 1 |
| TCMC5460 | C19H20O6 | (3'S)-Hydroxydeltoin | 344.1259884 | 1.4793 | 2.89 | 3.324 | 4 | 1 | 72.83 | 4 | 3 | 25 | 0 |
| TCMC6527 | C22H28O10 | 4'-O-Β-Glucopyranosyl-5-O-Methylvisamminol | 452.1682471 | -1.9337 | 2.78 | -0.052 | 7 | 4 | 134.91 | 5 | 4 | 32 | 0 |
| TCMC6952 | C8H16O | 7-Octen-4-Ol | 128.1201151 | -0.3603 | 2.23 | 2.441 | 1 | 1 | 20.23 | 5 | 0 | 9 | 0 |
| TCMC7012 | C17H24O2 | 1,8-Heptadecadiene-4,6-Diyne-3,10-Diol | 260.17763 | -0.342 | 3.11 | 4.591 | 2 | 2 | 40.46 | 8 | 0 | 19 | 0 |
Download Data
All data can be downloaded by:→ Selecting data type in the below download table
→ Then click the download button.
