Component ID |
TCMH75 |
Latin Name |
Bombyx mori |
English Name |
Silkworm larva |
Chinese Pinyin Name |
Bai Jiang Can |
中文名 |
白僵蚕 |
TCM Properties |
Salty, pungent,neutral |
TCM Meridians |
Liver,lung |
Therapeutic Class English |
For calming liver and containing wind |
Therapeutic Class Chinese |
平肝息风 |
Functions |
subdue endogenous wind and stop spasms, expel wind and stop pain, dispel toxins and disperse nodules |
Toxicity |
NA |
Geo-authentic habitats (道地产区) |
NA |
Reference |
CFDA |
Barcode ID |
GBGL25918-19 |
Barcode Source |
BOLDSYSTEMS |
Target ID | Gene Symbol | Target Name | Target Class | Uniprot ID |
---|---|---|---|---|
TCMT1 | EHMT2 | Histone-lysine N-methyltransferase, H3 lysine-9 specific 3 | Transferase | Q96KQ7 |
TCMT107 | GRIK2 | Glutamate receptor ionotropic kainate 2 | Ion channel | Q13002 |
TCMT108 | GRIA1 | Glutamate receptor ionotropic, AMPA 1 | Ion channel | P42261 |
TCMT109 | GRIA2 | Glutamate receptor ionotropic, AMPA 2 | Ion channel | P42262 |
TCMT11 | HIF1A | Hypoxia-inducible factor 1 alpha | Transcription factor | Q16665 |
TCMT110 | GRIA4 | Glutamate receptor ionotropic, AMPA 4 | Ion channel | P48058 |
TCMT111 | GRIK5 | Glutamate receptor ionotropic kainate 5 | Ion channel | Q16478 |
TCMT112 | ADORA3 | Adenosine A3 receptor | GPCR | P0DMS8 |
TCMT118 | MGAM | Maltase-glucoamylase | Hydrolase | O43451 |
TCMT124 | FUCA1 | Alpha-L-fucosidase I | Hydrolase | P04066 |
TCMT125 | GBA | Beta-glucocerebrosidase | Hydrolase | P04062 |
TCMT13 | APEX1 | DNA-(apurinic or apyrimidinic site) lyase | Lyase | P27695 |
TCMT130 | ALOX5 | Arachidonate 5-lipoxygenase | Oxidoreductase | P09917 |
TCMT131 | ACHE | Acetylcholinesterase | Hydrolase | P22303 |
TCMT132 | BCHE | Butyrylcholinesterase | Hydrolase | P06276 |
TCMT133 | CA1 | Carbonic anhydrase I | Lyase | P00915 |
TCMT134 | CA2 | Carbonic anhydrase II | Lyase | P00918 |
TCMT136 | CA12 | Carbonic anhydrase XII | Lyase | O43570 |
TCMT137 | CA9 | Carbonic anhydrase IX | Lyase | Q16790 |
TCMT138 | CA7 | Carbonic anhydrase VII | Lyase | P43166 |
TCMT139 | CA6 | Carbonic anhydrase VI | Lyase | P23280 |
TCMT142 | CA4 | Carbonic anhydrase IV | Lyase | P22748 |
TCMT150 | RORC | Nuclear receptor ROR-gamma | Nuclear receptor | P51449 |
TCMT156 | CYP19A1 | Cytochrome P450 19A1 | Oxidoreductase | P11511 |
TCMT162 | UGT1A1 | UDP-glucuronosyltransferase 1-1 | Transferase | P22309 |
TCMT17 | POLB | DNA polymerase beta | Transferase | P06746 |
TCMT18 | GAA | Lysosomal alpha-glucosidase | Hydrolase | P10253 |
TCMT187 | AR | Androgen Receptor | Nuclear receptor | P10275 |
TCMT193 | RELA | Nuclear factor NF-kappa-B p65 subunit | Transcription factor | Q04206 |
TCMT2 | MAPT | Microtubule-associated protein tau | Unclassified | P10636 |
TCMT206 | CYP2A6 | Cytochrome P450 2A6 | Oxidoreductase | P11509 |
TCMT207 | BACE1 | Beta-secretase 1 | Protease | P56817 |
TCMT213 | SLC22A1 | Solute carrier family 22 member 1 | Transporter | O15245 |
TCMT219 | CYP1A2 | Cytochrome P450 1A2 | Oxidoreductase | P05177 |
TCMT223 | AKR1B1 | Aldose reductase | Oxidoreductase | P15121 |
TCMT225 | CA13 | Carbonic anhydrase XIII | Lyase | Q8N1Q1 |
TCMT231 | GBA2 | Beta-glucosidase | Hydrolase | Q9HCG7 |
TCMT232 | ABCB1 | P-glycoprotein 1 | Transporter | P08183 |
TCMT239 | PIM1 | Serine/threonine-protein kinase PIM1 | Kinase | P11309 |
TCMT240 | AMY1A | Salivary alpha-amylase | Unclassified | P04745 |
TCMT241 | CHRNA7 | Neuronal acetylcholine receptor protein alpha-7 subunit | Ion channel | P36544 |
TCMT248 | CXCL8 | Interleukin-8 | Unclassified | P10145 |
TCMT268 | CYP2A13 | Cytochrome P450 2A13 | Oxidoreductase | Q16696 |
TCMT27 | DRD1 | Dopamine D1 receptor | GPCR | P21728 |
TCMT276 | SLCO2B1 | Solute carrier organic anion transporter family member 2B1 | Transporter | O94956 |
TCMT277 | SLCO1B3 | Solute carrier organic anion transporter family member 1B3 | Transporter | Q9NPD5 |
TCMT278 | SLCO1B1 | Solute carrier organic anion transporter family member 1B1 | Transporter | Q9Y6L6 |
TCMT287 | TAS2R31 | Taste receptor type 2 member 31 | GPCR | P59538 |
TCMT30 | PTGS2 | Cyclooxygenase-2 | Oxidoreductase | P35354 |
TCMT307 | KCNH2 | HERG | Ion channel | Q12809 |
TCMT33 | CYP3A4 | Cytochrome P450 3A4 | Oxidoreductase | P08684 |
TCMT41 | IDH1 | Isocitrate dehydrogenase [NADP] cytoplasmic | Oxidoreductase | O75874 |
TCMT45 | APP | Beta amyloid A4 protein | Unclassified | P05067 |
TCMT552 | CHRNA3 | Neuronal acetylcholine receptor subunit alpha-3 | Ion channel | P32297 |
TCMT558 | TOP2A | DNA topoisomerase II alpha | Isomerase | P11388 |
TCMT559 | ADRB2 | Beta-2 adrenergic receptor | GPCR | P07550 |
TCMT588 | DAO | D-amino-acid oxidase | Oxidoreductase | P14920 |
TCMT605 | EDNRA | Endothelin receptor ET-A | GPCR | P25101 |
TCMT636 | POLA1 | DNA polymerase alpha subunit | Transferase | P09884 |
TCMT653 | GRM1 | Metabotropic glutamate receptor 1 | GPCR | Q13255 |
TCMT654 | GRM5 | Metabotropic glutamate receptor 5 | GPCR | P41594 |
TCMT655 | GRM2 | Metabotropic glutamate receptor 2 | GPCR | Q14416 |
TCMT656 | GRM3 | Metabotropic glutamate receptor 3 | GPCR | Q14832 |
TCMT657 | GRM4 | Metabotropic glutamate receptor 4 | GPCR | Q14833 |
TCMT660 | GRM8 | Metabotropic glutamate receptor 8 | GPCR | O00222 |
TCMT661 | FOLH1 | Glutamate carboxypeptidase II | Hydrolase | Q04609 |
TCMT664 | SLC1A1 | Excitatory amino acid transporter 3 | Transporter | P43005 |
TCMT69 | THRB | Thyroid hormone receptor beta-1 | Nuclear receptor | P10828 |
TCMT8 | KDM4E | Lysine-specific demethylase 4D-like | Oxidoreductase | B2RXH2 |
Target ID | Target Name |
---|---|
TCMT1099 | Neuraminidase |
TCMT1207 | Legionella pneumophila |
TCMT1218 | Staphylococcus aureus |
TCMT1221 | Human herpesvirus 4 |
TCMT1229 | Enterococcus faecalis |
TCMT1232 | Pseudomonas aeruginosa |
TCMT1246 | Escherichia coli |
TCMT1251 | Candida albicans |
TCMT1253 | Penicillium chrysogenum |
TCMT1412 | Salmonella typhimurium |
TCMT1454 | Bacillus subtilis |
TCMT1455 | Mycobacterium tuberculosis H37Rv |
TCMT1462 | Streptococcus mutans |
TCMT1463 | Mycobacterium tuberculosis |
Ingredient ID: TCMC985
Formula: C3H7NO2
Ingredient ID: TCMC902
Formula: C27H46O
Ingredient ID: TCMC834
Formula: C4H8O
Ingredient ID: TCMC825
Formula: C31H42N6O7
Ingredient ID: TCMC791
Formula: C40H56
Ingredient ID: TCMC774
Formula: C7H8O
Ingredient ID: TCMC770
Formula: C7H6O2
Ingredient ID: TCMC70
Formula: C10H12N2O4
Ingredient ID: TCMC498
Formula: C9H6O3
Ingredient ID: TCMC445
Formula: C6H13NO3
Ingredient ID: TCMC348
Formula: C27H44O7
Ingredient ID: TCMC2387
Formula: C10H9NO2
Ingredient ID: TCMC2381
Formula: C8H10O
Ingredient ID: TCMC2204
Formula: C9H6O3
Ingredient ID: TCMC2051
Formula: C10H8O4
Ingredient ID: TCMC1872
Formula: C10H13NO2
Ingredient ID: TCMC1854
Formula: C5H10O
Ingredient ID: TCMC1849
Formula: C5H8O
Ingredient ID: TCMC1743
Formula: C10H14N2
Ingredient ID: TCMC1535
Formula: C6H14O6
Ingredient ID: TCMC1515
Formula: C30H50O
Ingredient ID: TCMC1480
Formula: C5H9NO4
Ingredient ID: TCMC1422
Formula: C17H14O7
Ingredient ID: TCMC1372
Formula: C8H7N
Ingredient ID: TCMC1329
Formula: C16H12O6
Ingredient ID: TCMC1184
Formula: C19H19N7O6
Ingredient ID: TCMC1167
Formula: C6H13NO3
Ingredient ID: TCMC1160
Formula: C16H12O7
Ingredient ID: TCMC1159
Formula: C10H12O2
Ingredient ID: TCMC1122
Formula: C28H44O
Ingredient ID: TCMC1090
Formula: C6H13NO4
Ingredient ID | Formulae | Name | MW | AlogP | MlogP | XlogP | # HBA | # HBD | PSA | # Rotatable Bond | # Ring | # Heacy Atom | Lipinski RO5 Violation |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
TCMC70 | C10H12N2O4 | (2R)-4-(2-Amino-3-Hydroxyphenyl)-2-Azaniumyl-4-Oxobutanoate | 224.08 | -2.586 | 1.9 | -2.464 | 5 | 4 | 126.64 | 8 | 1 | 16 | 0 |
TCMC348 | C27H44O7 | 20-Hydroxyecdysone | 480.31 | -1.1982 | 3.66 | 1.049 | 7 | 6 | 138.45 | 16 | 4 | 34 | 1 |
TCMC445 | C6H13NO3 | 3-Epifagomine | 147.09 | -2.2173 | 1.68 | -0.757 | 4 | 4 | 72.72 | 4 | 1 | 10 | 0 |
TCMC498 | C9H6O3 | 4-Hydroxycoumarins | 162.03 | -0.2931 | 2.12 | 2.292 | 2 | 1 | 46.53 | 1 | 2 | 12 | 0 |
TCMC770 | C7H6O2 | Benzoic Acid | 122.04 | -0.2398 | 2.01 | 2.666 | 2 | 1 | 37.3 | 2 | 1 | 9 | 0 |
TCMC774 | C7H8O | Benzyl Alcohol | 108.06 | -0.4487 | 2.12 | 2.409 | 1 | 1 | 20.23 | 2 | 1 | 8 | 0 |
TCMC791 | C40H56 | Beta Carotene | 536.44 | 8.935 | 5.86 | 14.734 | 0 | 0 | 0 | 20 | 2 | 40 | 1 |
TCMC825 | C31H42N6O7 | Bq-123 | 610.31 | -1.4727 | 3.44 | 2.506 | 13 | 6 | 203.76 | 16 | 4 | 44 | 2 |
TCMC834 | C4H8O | Butanal | 72.06 | -0.3943 | 1.79 | 1.156 | 1 | 0 | 17.07 | 3 | 0 | 5 | 0 |
TCMC902 | C27H46O | Cholesterol | 386.35 | 1.5548 | 4.32 | 10.518 | 1 | 1 | 20.23 | 11 | 4 | 28 | 1 |
TCMC985 | C3H7NO2 | D-Alanine | 89.05 | -1.0955 | 1.46 | -2.824 | 3 | 2 | 63.32 | 4 | 0 | 6 | 0 |
TCMC1090 | C6H13NO4 | Duvoglustat | 163.08 | -2.44 | 1.57 | -0.929 | 5 | 5 | 92.95 | 5 | 1 | 11 | 0 |
TCMC1122 | C28H44O | Ergosterol | 396.34 | 2.2555 | 4.43 | 9.499 | 1 | 1 | 20.23 | 11 | 4 | 29 | 1 |
TCMC1159 | C10H12O2 | Eugenol | 164.08 | 0.5166 | 2.34 | 2.484 | 0 | 1 | 29.46 | 5 | 1 | 12 | 0 |
TCMC1160 | C16H12O7 | Eupafolin | 316.06 | -2.3966 | 2.45 | 0.589 | 1 | 4 | 116.45 | 7 | 3 | 23 | 0 |
TCMC1167 | C6H13NO3 | Fagomine | 147.09 | -2.2173 | 1.68 | -0.757 | 4 | 4 | 72.72 | 4 | 1 | 10 | 0 |
TCMC1184 | C19H19N7O6 | Folic Acid | 441.14 | -2.6195 | 2.12 | 0.045 | 13 | 7 | 209.98 | 13 | 3 | 32 | 2 |
TCMC1329 | C16H12O6 | Hispidulin | 300.06 | -1.9363 | 2.56 | 1.123 | 1 | 3 | 96.22 | 6 | 3 | 22 | 0 |
TCMC1372 | C8H7N | Indole | 117.06 | -0.4204 | 2.23 | 2.45 | 1 | 1 | 15.79 | 0 | 2 | 9 | 0 |
TCMC1422 | C17H14O7 | Jaceosidine | 330.07 | -1.9881 | 2.56 | 0.679 | 1 | 3 | 105.45 | 8 | 3 | 24 | 0 |
TCMC1480 | C5H9NO4 | L-Glutamate | 147.05 | -1.6398 | 1.46 | -3.349 | 5 | 3 | 100.62 | 7 | 0 | 10 | 0 |
TCMC1515 | C30H50O | Lupeol | 426.39 | 3.2313 | 4.65 | 11.901 | 1 | 1 | 20.23 | 9 | 5 | 31 | 1 |
TCMC1535 | C6H14O6 | Mannitol | 182.08 | -2.9402 | 1.46 | -3.896 | 6 | 6 | 121.38 | 11 | 0 | 12 | 1 |
TCMC1743 | C10H14N2 | Nicotine | 162.12 | -0.4993 | 2.34 | 1.485 | 2 | 0 | 16.13 | 2 | 2 | 12 | 0 |
TCMC1849 | C5H8O | Pent-1-En-3-One | 84.06 | 0.4231 | 1.9 | 0.727 | 1 | 0 | 17.07 | 3 | 0 | 6 | 0 |
TCMC1854 | C5H10O | Pentanal | 86.07 | -0.6823 | 1.9 | 1.725 | 1 | 0 | 17.07 | 4 | 0 | 6 | 0 |
TCMC1872 | C10H13NO2 | Phenprobamate | 179.09 | 0.2552 | 2.23 | 4.754 | 3 | 2 | 53.31 | 6 | 1 | 13 | 0 |
TCMC2051 | C10H8O4 | Scopoletin | 192.04 | -0.2421 | 2.12 | 1.088 | 1 | 1 | 55.76 | 3 | 2 | 14 | 0 |
TCMC2204 | C9H6O3 | Umbelliferone | 162.03 | -0.1903 | 2.12 | 1.532 | 1 | 1 | 46.53 | 1 | 2 | 12 | 0 |
TCMC2381 | C8H10O | Phenylethyl Alcohol | 122.07 | -0.1931 | 2.23 | 3.189 | 1 | 1 | 20.23 | 3 | 1 | 9 | 0 |
TCMC2387 | C10H9NO2 | Indole-3-Acetic Acid | 175.06 | -0.6254 | 2.23 | 1.679 | 3 | 2 | 53.09 | 3 | 2 | 13 | 0 |