Component: Fagopyrum esculentum 荞麦

Description of the Component

Component ID
Latin Name
Fagopyrum esculentum
English Name
Common buckwheat
Chinese Pinyin Name
Qiao Mai
TCM Properties
TCM Meridians
Therapeutic Class English
Therapeutic Class Chinese
Geo-authentic habitats (道地产区)
Chinese Pharmacopoeia (2015)
Barcode ID
Barcode Source

TCM Prescriptions with the Component

Prescription ID Prescription English Name Prescription Chinese Name
TCMFx6833 Zhang Zhou Shen Qu 漳州神曲

Targeted Human Proteins by the Ingredient of Component

Target ID Gene Symbol Target Name Target Class Uniprot ID
TCMT1 EHMT2 Histone-lysine N-methyltransferase, H3 lysine-9 specific 3 Transferase Q96KQ7
TCMT101 PTPN1 Protein-tyrosine phosphatase 1B Hydrolase P18031
TCMT125 GBA Beta-glucocerebrosidase Hydrolase P04062
TCMT126 TERT Telomerase reverse transcriptase Transferase O14746
TCMT13 APEX1 DNA-(apurinic or apyrimidinic site) lyase Lyase P27695
TCMT131 ACHE Acetylcholinesterase Hydrolase P22303
TCMT132 BCHE Butyrylcholinesterase Hydrolase P06276
TCMT133 CA1 Carbonic anhydrase I Lyase P00915
TCMT134 CA2 Carbonic anhydrase II Lyase P00918
TCMT135 CA14 Carbonic anhydrase XIV Lyase Q9ULX7
TCMT136 CA12 Carbonic anhydrase XII Lyase O43570
TCMT137 CA9 Carbonic anhydrase IX Lyase Q16790
TCMT138 CA7 Carbonic anhydrase VII Lyase P43166
TCMT139 CA6 Carbonic anhydrase VI Lyase P23280
TCMT140 CA5B Carbonic anhydrase VB Lyase Q9Y2D0
TCMT141 CA5A Carbonic anhydrase VA Lyase P35218
TCMT142 CA4 Carbonic anhydrase IV Lyase P22748
TCMT143 CA3 Carbonic anhydrase III Lyase P07451
TCMT150 RORC Nuclear receptor ROR-gamma Nuclear receptor P51449
TCMT156 CYP19A1 Cytochrome P450 19A1 Oxidoreductase P11511
TCMT162 UGT1A1 UDP-glucuronosyltransferase 1-1 Transferase P22309
TCMT164 PTGS1 Cyclooxygenase-1 Oxidoreductase P23219
TCMT17 POLB DNA polymerase beta Transferase P06746
TCMT2 MAPT Microtubule-associated protein tau Unclassified P10636
TCMT207 BACE1 Beta-secretase 1 Protease P56817
TCMT210 CES2 Carboxylesterase 2 Hydrolase O00748
TCMT211 CES1 Acyl coenzyme A:cholesterol acyltransferase Transferase P23141
TCMT223 AKR1B1 Aldose reductase Oxidoreductase P15121
TCMT225 CA13 Carbonic anhydrase XIII Lyase Q8N1Q1
TCMT236 ESR2 Estrogen receptor beta Nuclear receptor Q92731
TCMT248 CXCL8 Interleukin-8 Unclassified P10145
TCMT276 SLCO2B1 Solute carrier organic anion transporter family member 2B1 Transporter O94956
TCMT277 SLCO1B3 Solute carrier organic anion transporter family member 1B3 Transporter Q9NPD5
TCMT278 SLCO1B1 Solute carrier organic anion transporter family member 1B1 Transporter Q9Y6L6
TCMT3 ALOX15 Arachidonate 15-lipoxygenase Oxidoreductase P16050
TCMT30 PTGS2 Cyclooxygenase-2 Oxidoreductase P35354
TCMT33 CYP3A4 Cytochrome P450 3A4 Oxidoreductase P08684
TCMT337 XPO1 Exportin-1 Unclassified O14980
TCMT341 NR1I2 Pregnane X receptor Nuclear receptor O75469
TCMT46 F3 Coagulation factor III Unclassified P13726
TCMT61 MCL1 Induced myeloid leukemia cell differentiation protein Mcl-1 Unclassified Q07820
TCMT63 PPARA Peroxisome proliferator-activated receptor alpha Nuclear receptor Q07869
TCMT64 PPARD Peroxisome proliferator-activated receptor delta Nuclear receptor Q03181
TCMT67 PPARG Peroxisome proliferator-activated receptor gamma Nuclear receptor P37231
TCMT8 KDM4E Lysine-specific demethylase 4D-like Oxidoreductase B2RXH2
TCMT82 ESR1 Estrogen receptor alpha Nuclear receptor P03372

Targeted Pathogenic Microbes by the Ingredient of Component

Target ID Target Name
TCMT1218 Staphylococcus aureus
TCMT1221 Human herpesvirus 4
TCMT1226 Klebsiella pneumoniae
TCMT1243 Aspergillus flavus
TCMT1246 Escherichia coli
TCMT1251 Candida albicans
TCMT1458 Filobasidiella neoformans

Ingredient Structrues

Ingredient ID: TCMC949
Formula: C9H6O2

Ingredient ID: TCMC836
Formula: C4H6O2

Ingredient ID: TCMC791
Formula: C40H56

Ingredient ID: TCMC497
Formula: C7H9NO

Ingredient ID: TCMC460
Formula: C4H8OS

Ingredient ID: TCMC434
Formula: C30H18O10

Ingredient ID: TCMC2232
Formula: C29H50O2

Ingredient ID: TCMC2231
Formula: C36H60O2

Ingredient ID: TCMC1843
Formula: C7H8O

Ingredient ID: TCMC1512
Formula: C9H11NO2

Ingredient ID: TCMC1496
Formula: C18H30O2

Ingredient ID: TCMC1153
Formula: C9H10O3


Ingredient ID Formulae Name MW AlogP MlogP XlogP # HBA # HBD PSA # Rotatable Bond # Ring # Heacy Atom Lipinski RO5 Violation
TCMC434 C30H18O10 3-[5,7-Dihydroxy-2-(4-Hydroxyphenyl)-4-Oxochromen-8-Yl]-5,7-Dihydroxy-2-(4-Hydroxyphenyl)Chromen-4-One 538.09 -3.8579 3.66 2.632 2 6 173.98 9 6 40 1
TCMC460 C4H8OS 3-Methylsulfanylpropanal 104.03 0.5469 1.68 1.2 1 0 42.37 4 0 6 0
TCMC497 C7H9NO 4-Hydroxybenzylamine 123.07 -1.1986 2.01 0.746 1 2 46.25 3 1 9 0
TCMC791 C40H56 Beta Carotene 536.44 8.935 5.86 14.734 0 0 0 20 2 40 1
TCMC836 C4H6O2 Butanedione 86.04 -0.5078 1.68 -0.164 2 0 34.14 3 0 6 0
TCMC949 C9H6O2 Coumarin 146.04 0.27 2.23 2.706 1 0 26.3 0 2 11 0
TCMC1153 C9H10O3 Ethylparaben 166.06 -0.1987 2.12 1.814 2 1 46.53 5 1 12 0
TCMC1496 C18H30O2 Linolenic Acid 278.22 -0.0979 3.22 7.538 2 1 37.3 15 0 20 2
TCMC1512 C9H11NO2 L-Phenylalanine 165.08 -1.0844 2.12 0.441 3 2 63.32 5 1 12 0
TCMC1843 C7H8O P-Cresol 108.06 0.1817 2.12 2.367 0 1 20.23 2 1 8 0
TCMC2231 C36H60O2 Vitamin A Palmitate 524.46 0.4962 5.2 14.548 2 0 26.3 27 1 38 2
TCMC2232 C29H50O2 Vitamin E 430.38 3.2935 4.43 10.938 0 1 29.46 21 2 31 2

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1. General Information of the Component  
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