Component: Rehmannia glutinosa 熟地黄


Description of the Component

Component ID
TCMH1966
Latin Name
Rehmannia glutinosa
English Name
Adhesive rehmannia cocked root
Chinese Pinyin Name
Shu Di Huang
中文名
熟地黄
TCM Properties
Minor Warm,Sweet
TCM Meridians
Liver,Kidney
Therapeutic Class English
For tonifying weakness
Therapeutic Class Chinese
补虚
Functions
nourish n and replenish blood, reinforce the essence of life and marrow
Toxicity
NA
Geo-authentic habitats (道地产区)
NA
Reference
Chinese Pharmacopoeia (2015)
Barcode ID
ITSAH4578-14
Barcode Source
BOLDSYSTEMS

TCM Prescriptions with the Component

Prescription ID Prescription English Name Prescription Chinese Name

Targeted Human Proteins by the Ingredient of Component

Target ID Gene Symbol Target Name Target Class Uniprot ID
TCMT1 EHMT2 Histone-lysine N-methyltransferase, H3 lysine-9 specific 3 Transferase Q96KQ7
TCMT11 HIF1A Hypoxia-inducible factor 1 alpha Transcription factor Q16665
TCMT112 ADORA3 Adenosine A3 receptor GPCR P0DMS8
TCMT126 TERT Telomerase reverse transcriptase Transferase O14746
TCMT130 ALOX5 Arachidonate 5-lipoxygenase Oxidoreductase P09917
TCMT133 CA1 Carbonic anhydrase I Lyase P00915
TCMT134 CA2 Carbonic anhydrase II Lyase P00918
TCMT135 CA14 Carbonic anhydrase XIV Lyase Q9ULX7
TCMT136 CA12 Carbonic anhydrase XII Lyase O43570
TCMT137 CA9 Carbonic anhydrase IX Lyase Q16790
TCMT138 CA7 Carbonic anhydrase VII Lyase P43166
TCMT139 CA6 Carbonic anhydrase VI Lyase P23280
TCMT140 CA5B Carbonic anhydrase VB Lyase Q9Y2D0
TCMT141 CA5A Carbonic anhydrase VA Lyase P35218
TCMT142 CA4 Carbonic anhydrase IV Lyase P22748
TCMT143 CA3 Carbonic anhydrase III Lyase P07451
TCMT150 RORC Nuclear receptor ROR-gamma Nuclear receptor P51449
TCMT151 PRKCA Protein kinase C alpha Kinase P17252
TCMT156 CYP19A1 Cytochrome P450 19A1 Oxidoreductase P11511
TCMT159 TYR Tyrosinase Oxidoreductase P14679
TCMT160 HTR7 Serotonin 7 (5-HT7) receptor GPCR P34969
TCMT161 HCAR2 Hydroxycarboxylic acid receptor 2 GPCR Q8TDS4
TCMT162 UGT1A1 UDP-glucuronosyltransferase 1-1 Transferase P22309
TCMT164 PTGS1 Cyclooxygenase-1 Oxidoreductase P23219
TCMT17 POLB DNA polymerase beta Transferase P06746
TCMT176 SOAT1 Acyl coenzyme A:cholesterol acyltransferase 1 Transferase P35610
TCMT18 GAA Lysosomal alpha-glucosidase Hydrolase P10253
TCMT189 DUSP3 Dual specificity protein phosphatase 3 Hydrolase P51452
TCMT195 MAP2K1 Dual specificity mitogen-activated protein kinase kinase 1 Kinase Q02750
TCMT2 MAPT Microtubule-associated protein tau Unclassified P10636
TCMT213 SLC22A1 Solute carrier family 22 member 1 Transporter O15245
TCMT219 CYP1A2 Cytochrome P450 1A2 Oxidoreductase P05177
TCMT221 ABCB11 Bile salt export pump Transporter O95342
TCMT223 AKR1B1 Aldose reductase Oxidoreductase P15121
TCMT248 CXCL8 Interleukin-8 Unclassified P10145
TCMT265 GSK3B Glycogen synthase kinase-3 beta Kinase P49841
TCMT267 GABRR1 GABA receptor rho-1 subunit Ion channel P24046
TCMT27 DRD1 Dopamine D1 receptor GPCR P21728
TCMT281 DPP4 Dipeptidyl peptidase IV Unclassified P27487
TCMT295 MMP1 Matrix metalloproteinase-1 Hydrolase P03956
TCMT296 ADORA1 Adenosine A1 receptor GPCR P30542
TCMT297 FABP4 Fatty acid binding protein adipocyte Unclassified P15090
TCMT298 FABP3 Fatty acid binding protein muscle Hydrolase P05413
TCMT3 ALOX15 Arachidonate 15-lipoxygenase Oxidoreductase P16050
TCMT30 PTGS2 Cyclooxygenase-2 Oxidoreductase P35354
TCMT306 MMP2 Matrix metalloproteinase-2 Hydrolase P08253
TCMT307 KCNH2 HERG Ion channel Q12809
TCMT320 MMP3 Matrix metalloproteinase 3 Hydrolase P08254
TCMT321 MMP9 Matrix metalloproteinase 9 Hydrolase P14780
TCMT322 MMP13 Matrix metalloproteinase 13 Hydrolase P45452
TCMT33 CYP3A4 Cytochrome P450 3A4 Oxidoreductase P08684
TCMT336 IDO1 Indoleamine 2,3-dioxygenase Oxidoreductase P14902
TCMT401 MET Hepatocyte growth factor receptor Kinase P08581
TCMT41 IDH1 Isocitrate dehydrogenase [NADP] cytoplasmic Oxidoreductase O75874
TCMT42 KMT2A Histone-lysine N-methyltransferase MLL Transferase Q03164
TCMT423 EGFR Epidermal growth factor receptor erbB1 Kinase P00533
TCMT45 APP Beta amyloid A4 protein Unclassified P05067
TCMT46 F3 Coagulation factor III Unclassified P13726
TCMT466 MAPK9 c-Jun N-terminal kinase 2 Kinase P45984
TCMT479 AKT1 Serine/threonine-protein kinase AKT Kinase P31749
TCMT507 MAPK14 MAP kinase p38 alpha Kinase Q16539
TCMT571 ADORA2B Adenosine A2b receptor GPCR P29275
TCMT588 DAO D-amino-acid oxidase Oxidoreductase P14920
TCMT592 XDH Xanthine dehydrogenase Oxidoreductase P47989
TCMT597 SLC28A3 Solute carrier family 28 member 3 Transporter Q9HAS3
TCMT6 NFKB1 Nuclear factor NF-kappa-B p105 subunit Transcription factor P19838
TCMT609 CTSL Cathepsin L Unclassified P07711
TCMT614 EGLN1 Egl nine homolog 1 Oxidoreductase Q9GZT9
TCMT619 HSP90AA1 Heat shock protein HSP 90-alpha Unclassified P07900
TCMT620 HSPA8 Heat shock cognate 71 kDa protein Unclassified P11142
TCMT624 HSP90AB1 Heat shock protein HSP 90-beta Unclassified P08238
TCMT63 PPARA Peroxisome proliferator-activated receptor alpha Nuclear receptor Q07869
TCMT632 PNP Purine nucleoside phosphorylase Transferase P00491
TCMT64 PPARD Peroxisome proliferator-activated receptor delta Nuclear receptor Q03181
TCMT654 GRM5 Metabotropic glutamate receptor 5 GPCR P41594
TCMT67 PPARG Peroxisome proliferator-activated receptor gamma Nuclear receptor P37231
TCMT69 THRB Thyroid hormone receptor beta-1 Nuclear receptor P10828
TCMT704 ERBB2 Receptor protein-tyrosine kinase erbB-2 Kinase P04626
TCMT707 ADORA2A Adenosine A2a receptor GPCR P29274
TCMT709 SLC28A2 Sodium/nucleoside cotransporter 2 Transporter O43868
TCMT710 SLC28A1 Sodium/nucleoside cotransporter 1 Transporter O00337
TCMT734 MMP12 Matrix metalloproteinase 12 Hydrolase P39900
TCMT8 KDM4E Lysine-specific demethylase 4D-like Oxidoreductase B2RXH2
TCMT80 MAPK1 MAP kinase ERK2 Kinase P28482
TCMT808 FABP5 Fatty acid binding protein epidermal Unclassified Q01469
TCMT809 FABP2 Fatty acid binding protein intestinal Unclassified P12104
TCMT810 TLR2 Toll-like receptor 2 Unclassified O60603
TCMT82 ESR1 Estrogen receptor alpha Nuclear receptor P03372
TCMT822 FUT7 Alpha-(1,3)-fucosyltransferase 7 Transferase Q11130


Targeted Pathogenic Microbes by the Ingredient of Component

Target ID Target Name
TCMT1088 Carbonic anhydrase
TCMT1090 Human immunodeficiency virus type 1 integrase
TCMT1178 Actinomyces viscosus
TCMT1212 Verticillium dahliae
TCMT1218 Staphylococcus aureus
TCMT1226 Klebsiella pneumoniae
TCMT1246 Escherichia coli
TCMT1251 Candida albicans
TCMT1253 Penicillium chrysogenum
TCMT1361 Neisseria meningitidis
TCMT1382 Plasmodium falciparum (isolate K1 / Thailand)
TCMT1438 Plasmodium falciparum
TCMT1442 Leishmania donovani
TCMT1454 Bacillus subtilis
TCMT1455 Mycobacterium tuberculosis H37Rv
TCMT1458 Filobasidiella neoformans
TCMT1462 Streptococcus mutans
TCMT1464 Hepatitis B virus

Ingredient Structrues

Ingredient ID: TCMC999
Formula: C10H20O2

Ingredient ID: TCMC916
Formula: C9H8O2

Ingredient ID: TCMC877
Formula: C15H22O10

Ingredient ID: TCMC770
Formula: C7H6O2

Ingredient ID: TCMC759
Formula: C22H44O2

Ingredient ID: TCMC747
Formula: C15H22O9

Ingredient ID: TCMC650
Formula: C6H14O6

Ingredient ID: TCMC632
Formula: C10H13N5O4

Ingredient ID: TCMC631
Formula: C5H5N5

Ingredient ID: TCMC614
Formula: C29H36O15

Ingredient ID: TCMC553
Formula: C6H6O3

Ingredient ID: TCMC2560
Formula: C9H20O

Ingredient ID: TCMC2491
Formula: C3H6O2

Ingredient ID: TCMC2223
Formula: C8H8O3

Ingredient ID: TCMC2209
Formula: C9H12N2O6

Ingredient ID: TCMC2201
Formula: C8H10O2

Ingredient ID: TCMC2116
Formula: C6H6O4

Ingredient ID: TCMC2111
Formula: C4H6O4

Ingredient ID: TCMC2105
Formula: C18H36O2

Ingredient ID: TCMC2037
Formula: C7H6O3

Ingredient ID: TCMC201
Formula: C35H46O20

Ingredient ID: TCMC1956
Formula: C7H6O4

Ingredient ID: TCMC1933
Formula: C23H30O6

Ingredient ID: TCMC1882
Formula: C8H6O4

Ingredient ID: TCMC1839
Formula: C7H6O3

Ingredient ID: TCMC1832
Formula: C16H30O2

Ingredient ID: TCMC1830
Formula: C16H32O2

Ingredient ID: TCMC1788
Formula: C18H34O2

Ingredient ID: TCMC1776
Formula: C8H16O2

Ingredient ID: TCMC1611
Formula: C14H28O2

Ingredient ID: TCMC1535
Formula: C6H14O6

Ingredient ID: TCMC1512
Formula: C9H11NO2

Ingredient ID: TCMC1495
Formula: C18H32O2

Ingredient ID: TCMC1467
Formula: C30H38O15

Ingredient ID: TCMC1378
Formula: C29H36O15

Ingredient ID: TCMC1358
Formula: C5H4N4O

Ingredient ID: TCMC1298
Formula: C10H13N5O5

Ingredient ID: TCMC1209
Formula: C4H9NO2

Ingredient ID: TCMC1202
Formula: C7H6O5

Ingredient ID: TCMC1187
Formula: C29H36O15

Ingredient ID: TCMC1173
Formula: C10H10O4