Component: Wolfiporia cocos 赤茯苓


Description of the Component

Component ID
TCMH256
Latin Name
Wolfiporia cocos
English Name
light red indian bread
Chinese Pinyin Name
Chi Fu Ling
中文名
赤茯苓
TCM Properties
TCM Meridians
Therapeutic Class English
Therapeutic Class Chinese
Functions
Toxicity
NA
Geo-authentic habitats (道地产区)
NA
Reference
SATCM
Barcode ID
GBPOL314-13
Barcode Source
BOLDSYSTEMS

TCM Prescriptions with the Component

Prescription ID Prescription English Name Prescription Chinese Name
TCMFx2882 Chu Shi Wei Ling Decoction 除湿胃苓汤
TCMF7313 Dao Shui Fu Ling Decoction 导水茯苓汤
TCMF2726 Five Ingredient Powder for Painful Urinary Dysfunction 五淋散
TCMF2782 Four Ingredient Decoction with Poria 四苓汤
TCMF2832 Hua Gai Powder 华盖散
TCMF7332 Hua Gai Powder 华盖散
TCMF2871 Huo Pu Xia Ling Decoction 藿朴夏苓汤
TCMF7365 Ju Pi Zhu Ru Decoction 橘皮竹茹汤
TCMFx4511 Pi Fu Bing Xue Du Pills 皮肤病血毒丸
TCMF7312 Wu Lin Powder 五淋散

Targeted Human Proteins by the Ingredient of Component

Target ID Gene Symbol Target Name Target Class Uniprot ID
TCMT13 APEX1 DNA-(apurinic or apyrimidinic site) lyase Lyase P27695
TCMT130 ALOX5 Arachidonate 5-lipoxygenase Oxidoreductase P09917
TCMT133 CA1 Carbonic anhydrase I Lyase P00915
TCMT134 CA2 Carbonic anhydrase II Lyase P00918
TCMT135 CA14 Carbonic anhydrase XIV Lyase Q9ULX7
TCMT136 CA12 Carbonic anhydrase XII Lyase O43570
TCMT137 CA9 Carbonic anhydrase IX Lyase Q16790
TCMT138 CA7 Carbonic anhydrase VII Lyase P43166
TCMT139 CA6 Carbonic anhydrase VI Lyase P23280
TCMT140 CA5B Carbonic anhydrase VB Lyase Q9Y2D0
TCMT141 CA5A Carbonic anhydrase VA Lyase P35218
TCMT142 CA4 Carbonic anhydrase IV Lyase P22748
TCMT143 CA3 Carbonic anhydrase III Lyase P07451
TCMT150 RORC Nuclear receptor ROR-gamma Nuclear receptor P51449
TCMT151 PRKCA Protein kinase C alpha Kinase P17252
TCMT156 CYP19A1 Cytochrome P450 19A1 Oxidoreductase P11511
TCMT160 HTR7 Serotonin 7 (5-HT7) receptor GPCR P34969
TCMT162 UGT1A1 UDP-glucuronosyltransferase 1-1 Transferase P22309
TCMT17 POLB DNA polymerase beta Transferase P06746
TCMT18 GAA Lysosomal alpha-glucosidase Hydrolase P10253
TCMT195 MAP2K1 Dual specificity mitogen-activated protein kinase kinase 1 Kinase Q02750
TCMT2 MAPT Microtubule-associated protein tau Unclassified P10636
TCMT207 BACE1 Beta-secretase 1 Protease P56817
TCMT223 AKR1B1 Aldose reductase Oxidoreductase P15121
TCMT225 CA13 Carbonic anhydrase XIII Lyase Q8N1Q1
TCMT240 AMY1A Salivary alpha-amylase Unclassified P04745
TCMT248 CXCL8 Interleukin-8 Unclassified P10145
TCMT265 GSK3B Glycogen synthase kinase-3 beta Kinase P49841
TCMT295 MMP1 Matrix metalloproteinase-1 Hydrolase P03956
TCMT297 FABP4 Fatty acid binding protein adipocyte Unclassified P15090
TCMT298 FABP3 Fatty acid binding protein muscle Hydrolase P05413
TCMT3 ALOX15 Arachidonate 15-lipoxygenase Oxidoreductase P16050
TCMT306 MMP2 Matrix metalloproteinase-2 Hydrolase P08253
TCMT320 MMP3 Matrix metalloproteinase 3 Hydrolase P08254
TCMT321 MMP9 Matrix metalloproteinase 9 Hydrolase P14780
TCMT401 MET Hepatocyte growth factor receptor Kinase P08581
TCMT466 MAPK9 c-Jun N-terminal kinase 2 Kinase P45984
TCMT47 BCL2 Apoptosis regulator Bcl-2 Ion channel P10415
TCMT479 AKT1 Serine/threonine-protein kinase AKT Kinase P31749
TCMT507 MAPK14 MAP kinase p38 alpha Kinase Q16539
TCMT592 XDH Xanthine dehydrogenase Oxidoreductase P47989
TCMT609 CTSL Cathepsin L Unclassified P07711
TCMT624 HSP90AB1 Heat shock protein HSP 90-beta Unclassified P08238
TCMT63 PPARA Peroxisome proliferator-activated receptor alpha Nuclear receptor Q07869
TCMT64 PPARD Peroxisome proliferator-activated receptor delta Nuclear receptor Q03181
TCMT67 PPARG Peroxisome proliferator-activated receptor gamma Nuclear receptor P37231
TCMT8 KDM4E Lysine-specific demethylase 4D-like Oxidoreductase B2RXH2
TCMT80 MAPK1 MAP kinase ERK2 Kinase P28482
TCMT808 FABP5 Fatty acid binding protein epidermal Unclassified Q01469
TCMT809 FABP2 Fatty acid binding protein intestinal Unclassified P12104
TCMT810 TLR2 Toll-like receptor 2 Unclassified O60603
TCMT82 ESR1 Estrogen receptor alpha Nuclear receptor P03372
TCMT83 CD38 Lymphocyte differentiation antigen CD38 Unclassified P28907


Targeted Pathogenic Microbes by the Ingredient of Component

Target ID Target Name
TCMT1212 Verticillium dahliae
TCMT1218 Staphylococcus aureus
TCMT1253 Penicillium chrysogenum
TCMT1361 Neisseria meningitidis
TCMT1382 Plasmodium falciparum (isolate K1 / Thailand)
TCMT1442 Leishmania donovani
TCMT1454 Bacillus subtilis
TCMT1462 Streptococcus mutans
TCMT1463 Mycobacterium tuberculosis

Ingredient Structrues

Ingredient ID: TCMC878
Formula: C15H14O6

Ingredient ID: TCMC631
Formula: C5H5N5

Ingredient ID: TCMC2554
Formula: C21H30O2

Ingredient ID: TCMC2511
Formula: C32H52O2

Ingredient ID: TCMC24
Formula: C15H14O6

Ingredient ID: TCMC2222
Formula: C8H8O4

Ingredient ID: TCMC1956
Formula: C7H6O4

Ingredient ID: TCMC1882
Formula: C8H6O4

Ingredient ID: TCMC1830
Formula: C16H32O2

Ingredient ID: TCMC1776
Formula: C8H16O2

Ingredient ID: TCMC1490
Formula: C12H14O2

Ingredient ID: TCMC148
Formula: C20H20O6

Ingredient ID: TCMC1081
Formula: C12H24O2

Properties

Ingredient ID Formulae Name MW AlogP MlogP XlogP # HBA # HBD PSA # Rotatable Bond # Ring # Heacy Atom Lipinski RO5 Violation
TCMC24 C15H14O6 (+)-Epicatechin 290.08 -2.494 2.45 0.406 1 5 110.38 6 3 21 0
TCMC148 C20H20O6 (E)-(E)-3-(4-Hydroxy-3-Methoxyphenyl)Allyl 3-(4-Hydroxy-3-Methoxyphenyl)Acrylate 356.13 -0.2748 3 3.186 2 2 85.22 12 2 26 0
TCMC631 C5H5N5 Adenine 135.05 -1.1703 1.46 -0.664 5 2 80.48 1 2 10 0
TCMC878 C15H14O6 Catechin 290.08 -2.494 2.45 0.406 1 5 110.38 6 3 21 0
TCMC1081 C12H24O2 Dodecanoate 200.18 -2.7457 2.56 5.294 2 1 37.3 12 0 14 1
TCMC1490 C12H14O2 Ligustilide 190.1 0.8112 2.56 2.819 2 0 26.3 3 2 14 0
TCMC1776 C8H16O2 Octanoic Acid 144.12 -1.5937 2.12 3.018 2 1 37.3 8 0 10 0
TCMC1830 C16H32O2 Palmitic Acid 256.24 -3.8977 3 7.57 2 1 37.3 16 0 18 2
TCMC1882 C8H6O4 Phthalic Acid 166.03 -0.4796 1.9 1.692 4 2 74.6 4 1 12 0
TCMC1956 C7H6O4 Protocatechuic Acid 154.03 -1.1604 1.79 0.536 2 3 77.76 4 1 11 0
TCMC2222 C8H8O4 Vanillic Acid 168.04 -0.7519 1.9 0.626 2 2 66.76 5 1 12 0
TCMC2511 C32H52O2 Beta-Amyrin Acetate 468.4 3.3907 4.76 12.286 2 0 26.3 11 5 34 1
TCMC2554 C21H30O2 Methyl Dehydroabietate 314.22 1.1524 3.55 8.267 2 0 26.3 8 3 23 1

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