Description of the Component
Component ID |
TCMH1377 |
Latin Name |
Astilbe chinensis |
English Name |
Ch inese astilbe |
Chinese Pinyin Name |
Luo Xin Fu |
中文名 |
落新妇 |
TCM Properties |
|
TCM Meridians |
|
Therapeutic Class English |
|
Therapeutic Class Chinese |
|
Functions |
|
Toxicity |
NA |
Geo-authentic habitats (道地产区) |
NA |
Reference |
CFDA |
Barcode ID |
ITSAJ4261-14 |
Barcode Source |
BOLDSYSTEMS |
TCM Prescriptions with the Component
| Prescription ID | Prescription English Name | Prescription Chinese Name |
|---|---|---|
| TCMFx6536 | Yu Shang Ling Capsules | 愈伤灵胶囊 |
Targeted Human Proteins by the Ingredient of Component
| Target ID | Gene Symbol | Target Name | Target Class | Uniprot ID |
|---|---|---|---|---|
| TCMT1 | EHMT2 | Histone-lysine N-methyltransferase, H3 lysine-9 specific 3 | Transferase | Q96KQ7 |
| TCMT130 | ALOX5 | Arachidonate 5-lipoxygenase | Oxidoreductase | P09917 |
| TCMT133 | CA1 | Carbonic anhydrase I | Lyase | P00915 |
| TCMT134 | CA2 | Carbonic anhydrase II | Lyase | P00918 |
| TCMT137 | CA9 | Carbonic anhydrase IX | Lyase | Q16790 |
| TCMT138 | CA7 | Carbonic anhydrase VII | Lyase | P43166 |
| TCMT139 | CA6 | Carbonic anhydrase VI | Lyase | P23280 |
| TCMT142 | CA4 | Carbonic anhydrase IV | Lyase | P22748 |
| TCMT156 | CYP19A1 | Cytochrome P450 19A1 | Oxidoreductase | P11511 |
| TCMT248 | CXCL8 | Interleukin-8 | Unclassified | P10145 |
| TCMT297 | FABP4 | Fatty acid binding protein adipocyte | Unclassified | P15090 |
| TCMT298 | FABP3 | Fatty acid binding protein muscle | Hydrolase | P05413 |
| TCMT301 | PTGES | Prostaglandin E synthase | Isomerase | O14684 |
| TCMT63 | PPARA | Peroxisome proliferator-activated receptor alpha | Nuclear receptor | Q07869 |
| TCMT64 | PPARD | Peroxisome proliferator-activated receptor delta | Nuclear receptor | Q03181 |
| TCMT67 | PPARG | Peroxisome proliferator-activated receptor gamma | Nuclear receptor | P37231 |
| TCMT808 | FABP5 | Fatty acid binding protein epidermal | Unclassified | Q01469 |
| TCMT809 | FABP2 | Fatty acid binding protein intestinal | Unclassified | P12104 |
| TCMT810 | TLR2 | Toll-like receptor 2 | Unclassified | O60603 |
Targeted Pathogenic Microbes by the Ingredient of Component
| Target ID | Target Name |
|---|---|
| TCMT1088 | Carbonic anhydrase |
| TCMT1218 | Staphylococcus aureus |
| TCMT1361 | Neisseria meningitidis |
| TCMT1382 | Plasmodium falciparum (isolate K1 / Thailand) |
| TCMT1442 | Leishmania donovani |
Ingredient Structrues
Ingredient ID: TCMC963
Formula: CHN
Ingredient ID: TCMC817
Formula: C16H22O4
Ingredient ID: TCMC77
Formula: C14H16O9
Ingredient ID: TCMC597
Formula: C20H20O5
Ingredient ID: TCMC301
Formula: C8H8O3
Ingredient ID: TCMC1830
Formula: C16H32O2
Ingredient ID: TCMC1062
Formula: C24H38O4
Properties
| Ingredient ID | Formulae | Name | MW | AlogP | MlogP | XlogP | # HBA | # HBD | PSA | # Rotatable Bond | # Ring | # Heacy Atom | Lipinski RO5 Violation |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| TCMC77 | C14H16O9 | (2R,3S,4S,10Bs)-3,4,8,10-Tetrahydroxy-2-(Hydroxymethyl)-9-Methoxy-3,4,4A,10B-Tetrahydro-2H-Pyrano[3,2-C]Isochromen-6-One | 328.08 | -2.8389 | 2.01 | -2.021 | 6 | 5 | 145.91 | 8 | 3 | 23 | 0 |
| TCMC301 | C8H8O3 | 2-(4-Hydroxyphenyl)Acetic Acid | 152.05 | -0.6653 | 2.01 | 1.062 | 2 | 2 | 57.53 | 4 | 1 | 11 | 0 |
| TCMC597 | C20H20O5 | 8-Prenylnaringenin | 340.13 | 0.063 | 3.11 | 2.367 | 1 | 3 | 86.99 | 8 | 3 | 25 | 0 |
| TCMC817 | C16H22O4 | Bis(2-Methylpropyl) Benzene-1,2-Dicarboxylate | 278.15 | 0.9868 | 2.78 | 4.49 | 4 | 0 | 52.6 | 12 | 1 | 20 | 0 |
| TCMC963 | CHN | Cyanide | 27.01 | 0.5675 | 1.46 | -0.357 | 1 | 0 | 23.79 | 0 | 0 | 2 | 0 |
| TCMC1062 | C24H38O4 | Dioctyl Benzene-1,2-Dicarboxylate | 390.28 | -3.5124 | 3.66 | 9.586 | 4 | 0 | 52.6 | 20 | 1 | 28 | 2 |
| TCMC1830 | C16H32O2 | Palmitic Acid | 256.24 | -3.8977 | 3 | 7.57 | 2 | 1 | 37.3 | 16 | 0 | 18 | 2 |
Download Data
All data can be downloaded by:→ Selecting data type in the below download table
→ Then click the download button.
