TCM-ID Component

Component: Herba glechomae 连钱草

Description of the Component

Component ID	TCMH1271
Latin Name	Herba glechomae
English Name	Longtube ground ivy herb
Chinese Pinyin Name	Lian Qian Cao
中文名	连钱草
TCM Properties
TCM Meridians
Therapeutic Class English
Therapeutic Class Chinese
Functions
Toxicity	NA
Geo-authentic habitats (道地产区)	Jiangxi Province
Reference	Chinese Pharmacopoeia (2015)
Barcode ID
Barcode Source

TCM Prescriptions with the Component

Prescription ID	Prescription English Name	Prescription Chinese Name
TCMFx3954	Dan Le Capsules	胆乐胶囊
TCMFx822	Dan Le Capsule	胆乐胶囊
TCMFx4311	Huo Luo Ding	活络酊
TCMFx7099	Huo Luo Zhi Tong Pills	活络止痛丸
TCMFx6976	Jing Dai Ning Capsules	经带宁胶囊
TCMFx4863	Niao Gan Ning Infusion	尿感宁冲剂
TCMFx620	Niao Gan Ning Granules	尿感宁颗粒
TCMFx4435	Pai Shi Granules	排石颗粒
TCMFx4427	Pai Shi Ointment	排石膏
TCMFx1000	Pai Shi Granules	排石颗粒
TCMFx5571	Qing Re Li Dan Infusion	清热利胆冲剂
TCMFx884	Qu Shang Xiao Zhong Tincture	祛伤消肿酊
TCMFx5076	She Xiang Die Da Feng Shi Ointment	麝香跌打风湿膏
TCMFx5726	Shuang Xiang Pai Shi Granules	双香排石颗粒
TCMFx5535	Tian Qi Die Da Feng Shi Ruan Ointment	田七跌打风湿软膏

Targeted Human Proteins by the Ingredient of Component

Target ID	Gene Symbol	Target Name	Target Class	Uniprot ID
TCMT44	GLO1	Glyoxalase I	Lyase	Q04760
TCMT753	SMAD3	Mothers against decapentaplegic homolog 3	Unclassified	P84022

Targeted Pathogenic Microbes by the Ingredient of Component

Target ID	Target Name

Ingredient Structrues

Ingredient ID: TCMC77
Formula: C14H16O9

Common Name	(2R,3S,4S,10Bs)-3,4,8,10-Tetrahydroxy-2-(Hydroxymethyl)-9-Methoxy-3,4,4A,10B-Tetrahydro-2H-Pyrano[3,2-C]Isochromen-6-One
IUPAC Name	(2R,3S,4S,10bS)-3,4,8,10-tetrahydroxy-2-(hydroxymethyl)-9-methoxy-3,4,4a,10b-tetrahydro-2H-pyrano[3,2-c]isochromen-6-one
Canonical SMILES	OC[C@H]1O[C@@H]2C([C@H]([C@@H]1O)O)OC(=O)c1c2c(O)c(c(c1)O)OC
Standard InCHI	InChI=1S/C14H16O9/c1-21-11-5(16)2-4-7(9(11)18)12-13(23-14(4)20)10(19)8(17)6(3-15)22-12/h2,6,8,10,12-13,15-19H,3H2,1H3/t6-,8-,10+,12+,13?/m1/s1
Standard InCHIKey	YWJXCIXBAKGUKZ-KRGNRWPNSA-N
External Identifiers	ChEMBL [CHEMBL1512567]; PubChem [24982180];
Reference of Component-Ingredient Pair	N/A

Occurrence of the ingredient across TCM components

Component ID	Latin Name	Pinyin Name	Chinese Name
TCMH7	Ardisiae japonicae	Ai Di Cha Qing Gao	矮地茶清膏
TCMH1271	Herba glechomae	Lian Qian Cao	连钱草
TCMH2372	Bergenia purpurascens	Yan Bai Cai	岩白菜
TCMH2715	Ardisia japonica	Zi Jin Niu	紫金牛
TCMH1377	Astilbe chinensis	Luo Xin Fu	落新妇
TCMH901	Saxifraga stolonifera	Hu Er Cao	虎耳草
TCMH35	Dysosma versipellis	Ba Jiao Lian	八角莲
TCMH6	Ardisiae japonicae	Ai Di Cha	矮地茶

Ingredient ID: TCMC1146
Formula: C12H14O4

Common Name	Ethyl Ferulate
IUPAC Name	ethyl (E)-3-(4-hydroxy-3-methoxyphenyl)prop-2-enoate
Canonical SMILES	CCOC(=O)/C=C/c1ccc(c(c1)OC)O
Standard InCHI	InChI=1S/C12H14O4/c1-3-16-12(14)7-5-9-4-6-10(13)11(8-9)15-2/h4-8,13H,3H2,1-2H3/b7-5+
Standard InCHIKey	ATJVZXXHKSYELS-FNORWQNLSA-N
External Identifiers	ChEMBL [CHEMBL286796]; PubChem [736681];
Reference of Component-Ingredient Pair	N/A

Occurrence of the ingredient across TCM components

Component ID	Latin Name	Pinyin Name	Chinese Name
TCMH1271	Herba glechomae	Lian Qian Cao	连钱草

Ingredient ID: TCMC1045
Formula: C9H10O4

Common Name	Dihydrocaffeic Acid
IUPAC Name	3-(3,4-dihydroxyphenyl)propanoic acid
Canonical SMILES	OC(=O)CCc1ccc(c(c1)O)O
Standard InCHI	InChI=1S/C9H10O4/c10-7-3-1-6(5-8(7)11)2-4-9(12)13/h1,3,5,10-11H,2,4H2,(H,12,13)
Standard InCHIKey	DZAUWHJDUNRCTF-UHFFFAOYSA-N
External Identifiers	ChEMBL [CHEMBL136927]; PubChem [348154];
Reference of Component-Ingredient Pair	N/A

Occurrence of the ingredient across TCM components

Component ID	Latin Name	Pinyin Name	Chinese Name
TCMH1271	Herba glechomae	Lian Qian Cao	连钱草
TCMH1186	Lycium chinense	Gou Qi Zi	枸杞子
TCMH2244	Prunella vulgaris	Xia Ku Cao	夏枯草
TCMH2710	Homo sapiens	Zi He Che	紫河车
TCMH449	Cortex lycii radicis	Di Gu Pi	地骨皮
TCMH700	Drynaria fortunei	Gu Sui Bu	骨碎补
TCMH1185	Lycium chinense	Gou Qi	枸杞
TCMH1734	Homo sapiens	Ren Zhong Bai	人中白

Properties

Ingredient ID	Formulae	Name	MW	AlogP	MlogP	XlogP	# HBA	# HBD	PSA	# Rotatable Bond	# Ring	# Heacy Atom	Lipinski RO5 Violation
TCMC77	C14H16O9	(2R,3S,4S,10Bs)-3,4,8,10-Tetrahydroxy-2-(Hydroxymethyl)-9-Methoxy-3,4,4A,10B-Tetrahydro-2H-Pyrano[3,2-C]Isochromen-6-One	328.08	-2.8389	2.01	-2.021	6	5	145.91	8	3	23	0
TCMC1045	C9H10O4	Dihydrocaffeic Acid	182.06	-1.0632	2.01	0.886	2	3	77.76	6	1	13	0
TCMC1146	C12H14O4	Ethyl Ferulate	222.09	0.1106	2.34	1.975	2	1	55.76	8	1	16	0

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Data Section	Select to Download
1. General Information of the Component
2. TCM Prescriptions with the Component
3. Putative Targets
4. Activity & References for Filtering Putative Targets
5. Ingredient Data & Chemical Structure Information (Properties, InChI, InChIkey, SMILES, etc.)