Component: Drynaria fortunei 骨碎补

Description of the Component

Component ID
Latin Name
Drynaria fortunei
English Name
Fortune’s drynaria rhizome
Chinese Pinyin Name
Gu Sui Bu
TCM Properties
TCM Meridians
Therapeutic Class English
Blood activation and stasis removal
Therapeutic Class Chinese
replenish the kidney, strengthen the bones, promote the healing of fracture, and relieve pain
Geo-authentic habitats (道地产区)
Zhejiang Province
Chinese Pharmacopoeia (2015)
Barcode ID
Barcode Source

TCM Prescriptions with the Component

Prescription ID Prescription English Name Prescription Chinese Name
TCMFx2516 Anti-Bone Growth Drink
TCMFx2968 Ba Li Powder 八厘散
TCMFx3168 Bai Hua Huo Xue Die Da Ointment 百花活血跌打膏
TCMFx3114 Ban Feng He Yao Wine 半枫荷药酒
TCMF3516 Bao Gu Zhui Feng Ointment 豹骨追风膏
TCMF3234 Bao Zhen Ointment 宝珍膏
TCMFx2159 Bone Piercing Bolus 骨刺丸
TCMFx1340 Bone Piercing Bolus 骨刺丸
TCMF6009 Chang Chun Hong Yao Tablets 长春红药片
TCMFx3771 Da Huo Luo Pills 大活络丸
TCMFx3786 Da Li Yao Wine 大力药酒
TCMFx3794 Da Qi Li Powder 大七厘散
TCMFx221 Da Qi Li Powder 大七厘散
TCMF367 Dan Lou Tablet 丹蒌片
TCMFx3341 Die Da Bang Yao Wine 跌打榜药酒
TCMFx3348 Die Da Feng Shi Wine 跌打风湿酒
TCMF3355 Die Da Feng Shi Yao Wine 跌打风湿药酒
TCMFx3402 Die Da Sun Shang Powder 跌打损伤散
TCMFx3386 Die Da Tablets 跌打片
TCMFx3418 Die Da Wan Hua You 跌打万花油
TCMFx3449 Die Da Zhi Tong Powder 跌打止痛散
TCMFx1391 Dieda Houxue Powder 跌打活血散
TCMFx2467 Dieda Houxue Powder 跌打活血散
TCMFx1440 Dieda Pills 跌打丸
TCMFx2620 Dieda Pills 跌打丸
TCMF3799 Du Zhong Yao Wine 杜仲药酒
TCMFx3337 Feng Shi An Tai Tablets 风湿安泰片
TCMF3375 Feng Shi Gao Yao 风湿膏药
TCMFx3644 Fo Shan Ren Shen Zai Zao Pills 佛山人参再造丸
TCMFx3635 Fo Shan Ren Shen Zai Zao Tablets 佛山人参再造片
TCMFx3150 Fu Fang Xia Tian Wu Tablets 复方夏天无片
TCMF3117 Fu Gui Feng Shi Ointment 附桂风湿膏
TCMF7079 Ge Jie Da Bu Pills 蛤蚧大补丸
TCMF4012 Ge Jie Zai Bu Pills 蛤蚧在补丸
TCMF3409 Gu Ci Ping Tablets 骨刺平片
TCMF3401 Gu Ci Tablets 骨刺片
TCMFx3482 Gu Lao Di Zhu She Oral Liquid 骨痨敌注射液
TCMFx3377 Gu Lou Shan Die Da Pills 古楼山跌打丸
TCMFx3369 Gu Lou Shan Die Da Wine 古楼山跌打酒
TCMF750 Gu Shu Kang Capsule 骨疏康胶囊
TCMF751 Gu Shu Kang Granules 骨疏康颗粒
TCMF745 Gu Xian Tablet 骨仙片
TCMF3532 Gu Xian Tablets 骨仙片
TCMF3537 Gu Yan Ling Tablets 骨炎灵片
TCMF3561 Gu Zeng Sheng Zhen Tong Ointment 骨增生镇痛膏
TCMFx3678 Guan Jie Jie Tong Ointment 关节解痛膏
TCMFx4433 Hong Hua Die Da Pills 红花跌打丸
TCMFx4264 Hui Sheng Zai Zao Pills 回生再造丸
TCMFx4274 Hui Tian Zai Zao Pills 回天再造丸
TCMFx4325 Huo Luo Pills 活络丸
TCMF4387 Huo Xue Li Shang Pills 活血理伤丸
TCMFx4611 Jie Gu Ling Tie Ointment 接骨灵贴膏
TCMFx4640 Jie Gu Pills 接骨丸
TCMFx4626 Jie Gu Qi Li Tablets 接骨七厘片
TCMFx4633 Jie Gu Qi Li Tablets 接骨七厘片
TCMFx4648 Jie Gu Xu Jin Tablets 接骨续筋片
TCMF4284 Jin Gu Ning Cha Ji 筋骨宁搽剂
TCMFx4292 Jin Gu Ning Ointment 筋骨宁膏
TCMFx4923 Jin Ji Hu Bu Pills 金鸡虎补丸
TCMFx4914 Jin Ji Hu Bu Tablets 金鸡虎补片
TCMF4474 Jing Tong Ling Yao Wine 颈痛灵药酒
TCMFx4780 Juan Bi Kang Sheng Pills 蠲痹抗生丸
TCMFx575 Kang Gu Zeng Sheng Capsule 抗骨增生胶囊
TCMFx4103 Kang Gu Zeng Sheng Tablets 抗骨增生片
TCMFx4110 Kang Gu Zhi Zeng Sheng Pills 抗骨质增生丸
TCMFx4211 Kang Shuan Capsules 抗栓胶囊
TCMFx2184 Kanggu Zengsheng Pills 抗骨增生丸
TCMFx1343 Kanggu Zengsheng Pills 抗骨增生丸
TCMFx4186 Liang Cai Xin Die Da Pills 梁财信跌打丸
TCMFx4205 Liao Yuan Qi Li Powder 辽源七厘散
TCMFx4823 Lu Wei Bu Shen Pills 鹿尾补肾丸
TCMFx4869 Luo Fu Shan Feng Shi Gao Yao 罗浮山风湿膏药
TCMF4601 Pian Tan Fu Yuan Pills 偏瘫复元丸
TCMFx5864 Qing Xuan Zhi Tan Pills 清眩治瘫丸
TCMFx80 Qing Xuan Zhi Tan Pills 清眩治瘫丸
TCMFx5109 Qu Feng Chu Shi Yao Wine 祛风除湿药酒
TCMFx5139 Qu Feng Shi Ointment 祛风湿膏
TCMF2606 Qufeng Shujin Pills 祛风舒筋丸
TCMF1431 Qufeng Shujin Pills 祛风舒筋丸
TCMFx1980 Relaxing Muscles and Tendons Capsule 伸筋丹胶囊
TCMFx1304 Relaxing Muscles and Tendons Capsule 伸筋丹胶囊
TCMFx5537 Ren Shen Zai Zao Pills 人参再造丸
TCMF5201 San Feng Huo Luo Pills 散风活络丸
TCMFx5065 San Qi Huo Xue Pills 三七活血丸
TCMFx211 San Qi Shang Yao Capsule 三七伤药胶囊
TCMFx212 San Qi Shang Yao Granules 三七伤药颗粒
TCMFx2048 Sanqi Shangyao Tablets 三七伤药片
TCMFx1318 Sanqi Shangyao Tablets; Fracture and Sprain Tablet of Notoginseng 三七伤药片
TCMFx5694 Shang Ke Wan Hua You 伤科万花油
TCMFx5745 Shang Shi Pills 伤湿丸
TCMF1435 Shangshi Zhitong Plaster 伤湿止痛膏
TCMF2614 Shangshi Zhitong Plaster 伤湿止痛膏
TCMFx5154 She Xiang Jie Gu Capsules 麝香接骨胶囊
TCMFx3228 Shen Gui Zai Zao Pills 参桂再造丸
TCMFx5312 Shen Jin Dan Capsules 伸筋丹胶囊
TCMF5673 Sheng Fa Pills 生发丸
TCMF5623 Sheng Xue Diao Wu Decoction 升血调无汤
TCMFx5605 Shu Feng Zai Zao Pills 疏风再造丸
TCMFx5398 Shu Jin Ding Tong Tablets 舒筋定痛片
TCMFx7120 Shu Jin Ding Tong Wine 舒筋定痛酒
TCMFx5407 Shu Jin Huo Xue Ding Tong Powder 舒筋活血定痛散
TCMF5424 Shu Jin Huo Xue Pills 舒筋活血丸
TCMFx1051 Shu Jin Huo Xue Ding Tong Powder 舒筋活血定痛散
TCMF1052 Shu Jin Tong Luo Granules 舒筋通络颗粒
TCMF5446 Shu Jin Zhi Tong Ding 舒筋止痛酊
TCMFx5349 Teng Huang Jian Gu Pills 藤黄健骨丸
TCMFx5535 Tian Qi Die Da Feng Shi Ruan Ointment 田七跌打风湿软膏
TCMFx5739 Tiao Gu Tablets 跳骨片
TCMFx5051 Tong Ren Da Huo Luo Pills 同仁大活络丸
TCMFx5125 Tong Zhong Ling 痛肿灵
TCMFx5279 Wai Yong Die Da Zhi Tong Ointment 外用跌打止痛膏
TCMFx5293 Wai Yong Wu Di Ointment 外用无敌膏
TCMF5409 Wang Bi Granules 尪痹颗粒
TCMF554 Wang Bi Granules 尪痹颗粒
TCMF553 Wang Bi Tablet 尪痹片
TCMF5417 Wang Bi Tablets 尪痹片
TCMF5323 Wu Di Dan Capsules 无敌丹胶囊
TCMF5331 Wu Di Yao Wine 无敌药酒
TCMFx6320 Xiao Shuan Zai Zao Pills 消栓再造丸
TCMF6178 Yao Zhui Bi Tong Pills 腰椎痹痛丸
TCMF6624 Yi Shen Bu Gu Oral Liquid 益肾补骨液
TCMFx470 Zai Zao Pills 再造丸
TCMFx6310 Zheng Gu Ointment 正骨膏
TCMFx6092 Zhi Shang Die Da Pills 治伤跌打丸
TCMFx7131 Zhi Shang Ruan Ointment 治伤软膏
TCMFx6109 Zhi Shang Xiao Yu Pills 治伤消瘀丸
TCMFx322 Zhi Tong Zi Jin Pills 止痛紫金丸
TCMFx6224 Zhong Feng Zai Zao Pills 中风再造丸
TCMF465 Zhuang Gu Guan Jie Pills 壮骨关节丸
TCMF6484 Zhuang Gu She Xiang Zhi Tong Ointment 壮骨麝香止痛膏
TCMF488 Zhuang Gu Shen Jin Capsule 壮骨伸筋胶囊
TCMF6504 Zhuang Xue Tablets 壮血片
TCMF6511 Zhuang Xue Yao Wine 壮血药酒
TCMF6617 Zhui Feng Huo Xue Ointment 追风活血膏

Targeted Human Proteins by the Ingredient of Component

Target ID Gene Symbol Target Name Target Class Uniprot ID
TCMT1 EHMT2 Histone-lysine N-methyltransferase, H3 lysine-9 specific 3 Transferase Q96KQ7
TCMT100 TTR Transthyretin Unclassified P02766
TCMT101 PTPN1 Protein-tyrosine phosphatase 1B Hydrolase P18031
TCMT11 HIF1A Hypoxia-inducible factor 1 alpha Transcription factor Q16665
TCMT13 APEX1 DNA-(apurinic or apyrimidinic site) lyase Lyase P27695
TCMT130 ALOX5 Arachidonate 5-lipoxygenase Oxidoreductase P09917
TCMT131 ACHE Acetylcholinesterase Hydrolase P22303
TCMT133 CA1 Carbonic anhydrase I Lyase P00915
TCMT134 CA2 Carbonic anhydrase II Lyase P00918
TCMT135 CA14 Carbonic anhydrase XIV Lyase Q9ULX7
TCMT136 CA12 Carbonic anhydrase XII Lyase O43570
TCMT137 CA9 Carbonic anhydrase IX Lyase Q16790
TCMT138 CA7 Carbonic anhydrase VII Lyase P43166
TCMT139 CA6 Carbonic anhydrase VI Lyase P23280
TCMT140 CA5B Carbonic anhydrase VB Lyase Q9Y2D0
TCMT141 CA5A Carbonic anhydrase VA Lyase P35218
TCMT142 CA4 Carbonic anhydrase IV Lyase P22748
TCMT143 CA3 Carbonic anhydrase III Lyase P07451
TCMT150 RORC Nuclear receptor ROR-gamma Nuclear receptor P51449
TCMT156 CYP19A1 Cytochrome P450 19A1 Oxidoreductase P11511
TCMT159 TYR Tyrosinase Oxidoreductase P14679
TCMT161 HCAR2 Hydroxycarboxylic acid receptor 2 GPCR Q8TDS4
TCMT162 UGT1A1 UDP-glucuronosyltransferase 1-1 Transferase P22309
TCMT166 AKR1C2 Aldo-keto reductase family 1 member C2 Oxidoreductase P52895
TCMT167 AKR1C3 Aldo-keto-reductase family 1 member C3 Oxidoreductase P42330
TCMT168 AKR1C4 Aldo-keto reductase family 1 member C4 Oxidoreductase P17516
TCMT17 POLB DNA polymerase beta Transferase P06746
TCMT175 GPBAR1 G-protein coupled bile acid receptor 1 GPCR Q8TDU6
TCMT18 GAA Lysosomal alpha-glucosidase Hydrolase P10253
TCMT187 AR Androgen Receptor Nuclear receptor P10275
TCMT189 DUSP3 Dual specificity protein phosphatase 3 Hydrolase P51452
TCMT2 MAPT Microtubule-associated protein tau Unclassified P10636
TCMT207 BACE1 Beta-secretase 1 Protease P56817
TCMT213 SLC22A1 Solute carrier family 22 member 1 Transporter O15245
TCMT218 CYP2B6 Cytochrome P450 2B6 Oxidoreductase P20813
TCMT22 ALPI Intestinal alkaline phosphatase Hydrolase P09923
TCMT223 AKR1B1 Aldose reductase Oxidoreductase P15121
TCMT225 CA13 Carbonic anhydrase XIII Lyase Q8N1Q1
TCMT23 ALPL Alkaline phosphatase, tissue-nonspecific isozyme Hydrolase P05186
TCMT236 ESR2 Estrogen receptor beta Nuclear receptor Q92731
TCMT240 AMY1A Salivary alpha-amylase Unclassified P04745
TCMT248 CXCL8 Interleukin-8 Unclassified P10145
TCMT261 DAPK1 Death-associated protein kinase 1 Kinase P53355
TCMT265 GSK3B Glycogen synthase kinase-3 beta Kinase P49841
TCMT276 SLCO2B1 Solute carrier organic anion transporter family member 2B1 Transporter O94956
TCMT277 SLCO1B3 Solute carrier organic anion transporter family member 1B3 Transporter Q9NPD5
TCMT278 SLCO1B1 Solute carrier organic anion transporter family member 1B1 Transporter Q9Y6L6
TCMT280 AKR1B10 Aldo-keto reductase family 1 member B10 Oxidoreductase O60218
TCMT281 DPP4 Dipeptidyl peptidase IV Unclassified P27487
TCMT295 MMP1 Matrix metalloproteinase-1 Hydrolase P03956
TCMT3 ALOX15 Arachidonate 15-lipoxygenase Oxidoreductase P16050
TCMT306 MMP2 Matrix metalloproteinase-2 Hydrolase P08253
TCMT320 MMP3 Matrix metalloproteinase 3 Hydrolase P08254
TCMT321 MMP9 Matrix metalloproteinase 9 Hydrolase P14780
TCMT33 CYP3A4 Cytochrome P450 3A4 Oxidoreductase P08684
TCMT336 IDO1 Indoleamine 2,3-dioxygenase Oxidoreductase P14902
TCMT34 CYP2D6 Cytochrome P450 2D6 Oxidoreductase P10635
TCMT344 AOX1 Aldehyde oxidase Oxidoreductase Q06278
TCMT348 SULT1A1 Sulfotransferase 1A1 Transferase P50225
TCMT41 IDH1 Isocitrate dehydrogenase [NADP] cytoplasmic Oxidoreductase O75874
TCMT423 EGFR Epidermal growth factor receptor erbB1 Kinase P00533
TCMT45 APP Beta amyloid A4 protein Unclassified P05067
TCMT47 BCL2 Apoptosis regulator Bcl-2 Ion channel P10415
TCMT591 ESRRA Estrogen-related receptor alpha Nuclear receptor P11474
TCMT599 UBE2N Ubiquitin-conjugating enzyme E2 N Transferase P61088
TCMT6 NFKB1 Nuclear factor NF-kappa-B p105 subunit Transcription factor P19838
TCMT60 FASN Fatty acid synthase Unclassified P49327
TCMT601 F2 Thrombin Unclassified P00734
TCMT609 CTSL Cathepsin L Unclassified P07711
TCMT69 THRB Thyroid hormone receptor beta-1 Nuclear receptor P10828
TCMT725 CACNA1C Voltage-gated L-type calcium channel alpha-1C subunit Ion channel Q13936
TCMT753 SMAD3 Mothers against decapentaplegic homolog 3 Unclassified P84022
TCMT8 KDM4E Lysine-specific demethylase 4D-like Oxidoreductase B2RXH2
TCMT80 MAPK1 MAP kinase ERK2 Kinase P28482
TCMT82 ESR1 Estrogen receptor alpha Nuclear receptor P03372
TCMT822 FUT7 Alpha-(1,3)-fucosyltransferase 7 Transferase Q11130
TCMT83 CD38 Lymphocyte differentiation antigen CD38 Unclassified P28907
TCMT87 CYP2C9 Cytochrome P450 2C9 Oxidoreductase P11712
TCMT910 ESRRB Estrogen-related receptor beta Nuclear receptor O95718
TCMT95 MPG DNA-3-methyladenine glycosylase Hydrolase P29372
TCMT974 GPER1 G-protein coupled estrogen receptor 1 GPCR Q99527
TCMT99 SHBG Testis-specific androgen-binding protein Unclassified P04278

Targeted Pathogenic Microbes by the Ingredient of Component

Target ID Target Name
TCMT1108 Integrase
TCMT1175 Human immunodeficiency virus
TCMT1178 Actinomyces viscosus
TCMT1189 Pseudomonas fluorescens
TCMT1212 Verticillium dahliae
TCMT1218 Staphylococcus aureus
TCMT1222 Plasmodium falciparum D6
TCMT1251 Candida albicans
TCMT1438 Plasmodium falciparum
TCMT1465 Entamoeba histolytica

Ingredient Structrues

Ingredient ID: TCMC913
Formula: C15H14O6

Ingredient ID: TCMC90
Formula: C15H14O7

Ingredient ID: TCMC880
Formula: C6H6O2

Ingredient ID: TCMC878
Formula: C15H14O6

Ingredient ID: TCMC847
Formula: C9H8O4

Ingredient ID: TCMC801
Formula: C29H50O

Ingredient ID: TCMC711
Formula: C21H20O10

Ingredient ID: TCMC4408
Formula: C28H48O

Ingredient ID: TCMC4324
Formula: C29H48O

Ingredient ID: TCMC3966
Formula: C29H50O

Ingredient ID: TCMC2709
Formula: C21H20O10

Ingredient ID: TCMC24
Formula: C15H14O6

Ingredient ID: TCMC1956
Formula: C7H6O4

Ingredient ID: TCMC1839
Formula: C7H6O3

Ingredient ID: TCMC182
Formula: C9H8O4

Ingredient ID: TCMC1735
Formula: C27H32O14

Ingredient ID: TCMC13
Formula: C15H14O6

Ingredient ID: TCMC1202
Formula: C7H6O5

Ingredient ID: TCMC1133
Formula: C18H24O2

Ingredient ID: TCMC1045
Formula: C9H10O4


Ingredient ID Formulae Name MW AlogP MlogP XlogP # HBA # HBD PSA # Rotatable Bond # Ring # Heacy Atom Lipinski RO5 Violation
TCMC13 C15H14O6 (-)-Epicatechin 290.08 -2.494 2.45 0.406 1 5 110.38 6 3 21 0
TCMC24 C15H14O6 (+)-Epicatechin 290.08 -2.494 2.45 0.406 1 5 110.38 6 3 21 0
TCMC90 C15H14O7 (2S,3S)-2-(3,4,5-Trihydroxy-Phenyl)-Chroman-3,5,7-Triol 306.07 -2.9543 2.34 -0.128 1 6 130.61 7 3 22 1
TCMC182 C9H8O4 (Z)-3-(3,4-Dihydroxyphenyl)Prop-2-Enoic Acid 180.04 -0.7993 2.01 1.141 2 3 77.76 5 1 13 0
TCMC711 C21H20O10 Apigetrin 432.11 -3.6314 2.67 0.459 6 6 166.14 10 4 31 1
TCMC801 C29H50O Beta-Sitosterol 414.39 1.3 4.54 11.595 1 1 20.23 13 4 30 1
TCMC847 C9H8O4 Caffeic Acid 180.04 -0.7993 2.01 1.141 2 3 77.76 5 1 13 0
TCMC878 C15H14O6 Catechin 290.08 -2.494 2.45 0.406 1 5 110.38 6 3 21 0
TCMC880 C6H6O2 Catechol 110.04 -0.9206 1.9 1.299 0 2 40.46 2 1 8 0
TCMC913 C15H14O6 Cianidanol 290.08 -2.494 2.45 0.406 1 5 110.38 6 3 21 0
TCMC1045 C9H10O4 Dihydrocaffeic Acid 182.06 -1.0632 2.01 0.886 2 3 77.76 6 1 13 0
TCMC1133 C18H24O2 Estradiol 272.18 -0.4699 3.22 4.646 1 2 40.46 3 4 20 0
TCMC1202 C7H6O5 Gallic Acid 170.02 -1.6207 1.68 0.002 2 4 97.99 5 1 12 0
TCMC1735 C27H32O14 Naringin 580.18 -4.8082 2.89 -1.045 10 8 225.06 15 5 41 1
TCMC1839 C7H6O3 Paraben 138.03 -0.7001 1.9 1.07 2 2 57.53 3 1 10 0
TCMC1956 C7H6O4 Protocatechuic Acid 154.03 -1.1604 1.79 0.536 2 3 77.76 4 1 11 0
TCMC2709 C21H20O10 Apigenin-7-O-Glucoside 432.11 -3.6314 2.67 0.459 6 6 166.14 10 4 31 1
TCMC3966 C29H50O Sitosterol,Β-Sitosterol 414.3861662 1.3 4.54 11.595 1 1 20.23 6 4 30 1
TCMC4324 C29H48O Stigmasterol 412.3705162 1.2566 4.54 11.071 1 1 20.23 5 4 30 1
TCMC4408 C28H48O Campesterol,M-Cresol 400.3705162 1.9762 4.43 11.026 1 1 20.23 5 4 29 1

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1. General Information of the Component  
2. TCM Prescriptions with the Component  
3. Putative Targets  
4. Activity & References for Filtering Putative Targets  
5. Ingredient Data & Chemical Structure Information (Properties, InChI, InChIkey, SMILES, etc.)