Description of the Component
Component ID |
TCMH1045 |
Latin Name |
Piper sarmentosum |
English Name |
Sarmentose pepper |
Chinese Pinyin Name |
Jia Ju |
中文名 |
假蒟 |
TCM Properties |
|
TCM Meridians |
|
Therapeutic Class English |
|
Therapeutic Class Chinese |
|
Functions |
|
Toxicity |
NA |
Geo-authentic habitats (道地产区) |
NA |
Reference |
Chinese Pharmacopoeia (2015) |
Barcode ID |
GBVY2651-14, GBVP7053-15 |
Barcode Source |
BOLDSYSTEMS |
Targeted Human Proteins by the Ingredient of Component
| Target ID | Gene Symbol | Target Name | Target Class | Uniprot ID |
|---|---|---|---|---|
| TCMT100 | TTR | Transthyretin | Unclassified | P02766 |
| TCMT114 | CNR2 | Cannabinoid CB2 receptor | GPCR | P34972 |
| TCMT133 | CA1 | Carbonic anhydrase I | Lyase | P00915 |
| TCMT134 | CA2 | Carbonic anhydrase II | Lyase | P00918 |
| TCMT137 | CA9 | Carbonic anhydrase IX | Lyase | Q16790 |
| TCMT141 | CA5A | Carbonic anhydrase VA | Lyase | P35218 |
| TCMT142 | CA4 | Carbonic anhydrase IV | Lyase | P22748 |
| TCMT156 | CYP19A1 | Cytochrome P450 19A1 | Oxidoreductase | P11511 |
| TCMT160 | HTR7 | Serotonin 7 (5-HT7) receptor | GPCR | P34969 |
| TCMT161 | HCAR2 | Hydroxycarboxylic acid receptor 2 | GPCR | Q8TDS4 |
| TCMT215 | CYP1A1 | Cytochrome P450 1A1 | Oxidoreductase | P04798 |
| TCMT219 | CYP1A2 | Cytochrome P450 1A2 | Oxidoreductase | P05177 |
| TCMT223 | AKR1B1 | Aldose reductase | Oxidoreductase | P15121 |
| TCMT257 | CYP1B1 | Cytochrome P450 1B1 | Oxidoreductase | Q16678 |
| TCMT281 | DPP4 | Dipeptidyl peptidase IV | Unclassified | P27487 |
| TCMT302 | HMGCR | HMG-CoA reductase | Oxidoreductase | P04035 |
| TCMT33 | CYP3A4 | Cytochrome P450 3A4 | Oxidoreductase | P08684 |
| TCMT34 | CYP2D6 | Cytochrome P450 2D6 | Oxidoreductase | P10635 |
| TCMT41 | IDH1 | Isocitrate dehydrogenase [NADP] cytoplasmic | Oxidoreductase | O75874 |
| TCMT45 | APP | Beta amyloid A4 protein | Unclassified | P05067 |
| TCMT588 | DAO | D-amino-acid oxidase | Oxidoreductase | P14920 |
| TCMT654 | GRM5 | Metabotropic glutamate receptor 5 | GPCR | P41594 |
| TCMT67 | PPARG | Peroxisome proliferator-activated receptor gamma | Nuclear receptor | P37231 |
| TCMT82 | ESR1 | Estrogen receptor alpha | Nuclear receptor | P03372 |
| TCMT87 | CYP2C9 | Cytochrome P450 2C9 | Oxidoreductase | P11712 |
Targeted Pathogenic Microbes by the Ingredient of Component
| Target ID | Target Name |
|---|---|
| TCMT1181 | Mycobacterium tuberculosis H37Ra |
| TCMT1218 | Staphylococcus aureus |
| TCMT1251 | Candida albicans |
| TCMT1294 | Human parainfluenza virus 3 |
| TCMT1438 | Plasmodium falciparum |
| TCMT1454 | Bacillus subtilis |
| TCMT1455 | Mycobacterium tuberculosis H37Rv |
| TCMT1463 | Mycobacterium tuberculosis |
| TCMT1465 | Entamoeba histolytica |
Ingredient Structrues
Ingredient ID: TCMC916
Formula: C9H8O2
Ingredient ID: TCMC801
Formula: C29H50O
Ingredient ID: TCMC770
Formula: C7H6O2
Ingredient ID: TCMC2716
Formula: C26H37NO3
Ingredient ID: TCMC2597
Formula: C14H23NO
Ingredient ID: TCMC2507
Formula: C20H25NO3
Ingredient ID: TCMC2461
Formula: C18H21NO3
Ingredient ID: TCMC2403
Formula: C29H24O6
Ingredient ID: TCMC2372
Formula: C20H23NO3
Ingredient ID: TCMC2180
Formula: C12H16O3
Ingredient ID: TCMC2107
Formula: C29H48O
Ingredient ID: TCMC2088
Formula: C7H6O2.Na
Ingredient ID: TCMC2066
Formula: C20H18O6
Ingredient ID: TCMC1898
Formula: C15H12O4
Ingredient ID: TCMC1848
Formula: C14H25NO
Ingredient ID: TCMC1745
Formula: C16H29NO
Ingredient ID: TCMC1299
Formula: C24H33NO3
Ingredient ID: TCMC1101
Formula: C11H12O3
Properties
| Ingredient ID | Formulae | Name | MW | AlogP | MlogP | XlogP | # HBA | # HBD | PSA | # Rotatable Bond | # Ring | # Heacy Atom | Lipinski RO5 Violation |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| TCMC770 | C7H6O2 | Benzoic Acid | 122.04 | -0.2398 | 2.01 | 2.666 | 2 | 1 | 37.3 | 2 | 1 | 9 | 0 |
| TCMC801 | C29H50O | Beta-Sitosterol | 414.39 | 1.3 | 4.54 | 11.595 | 1 | 1 | 20.23 | 13 | 4 | 30 | 1 |
| TCMC916 | C9H8O2 | Cinnamic Acid | 148.05 | 0.1213 | 2.23 | 3.904 | 2 | 1 | 37.3 | 3 | 1 | 11 | 0 |
| TCMC1101 | C11H12O3 | Elemicin | 192.08 | 0.6742 | 2.34 | 2.486 | 0 | 0 | 27.69 | 4 | 2 | 14 | 0 |
| TCMC1299 | C24H33NO3 | Guineensine | 383.25 | 0.6319 | 3.66 | 7.693 | 2 | 1 | 51.05 | 15 | 2 | 28 | 2 |
| TCMC1745 | C16H29NO | N-Isobutyl-(2E,4E)-Dodecadienamide | 251.22 | -0.0255 | 3 | 6.025 | 2 | 1 | 32.59 | 14 | 0 | 18 | 1 |
| TCMC1848 | C14H25NO | Pellitorin | 223.19 | 0.5505 | 2.78 | 4.887 | 2 | 1 | 32.59 | 12 | 0 | 16 | 0 |
| TCMC1898 | C15H12O4 | Pinocembrin | 256.07 | -1.3541 | 2.67 | 2.493 | 1 | 2 | 66.76 | 3 | 3 | 19 | 0 |
| TCMC2066 | C20H18O6 | Sesamin | 354.11 | -1.6034 | 3 | 2.576 | 2 | 0 | 55.38 | 2 | 6 | 26 | 0 |
| TCMC2088 | C7H6O2.Na | Sodium Benzoate | 121.03 | -0.9176 | 2.01 | 2.185 | 2 | 0 | 40.13 | 2 | 1 | 9 | 0 |
| TCMC2107 | C29H48O | Stigmasterol | 412.37 | 1.2566 | 4.54 | 11.071 | 1 | 1 | 20.23 | 12 | 4 | 30 | 1 |
| TCMC2180 | C12H16O3 | Trans-Asarone | 208.11 | 0.7519 | 2.45 | 2.669 | 0 | 0 | 27.69 | 8 | 1 | 15 | 0 |
| TCMC2372 | C20H23NO3 | 9-(Benzo[D][1,3]Dioxol-5-Yl)-1-(Pyrrolidin-1-Yl)Nona-2,4,8-Trien-1-One | 325.17 | 0.3176 | 3.22 | 4.569 | 2 | 0 | 38.77 | 7 | 3 | 24 | 0 |
| TCMC2403 | C29H24O6 | Dichamanetin | 468.16 | -1.3623 | 3.99 | 5.633 | 1 | 4 | 107.22 | 9 | 5 | 35 | 1 |
| TCMC2461 | C18H21NO3 | Sarmentosine | 299.15 | -0.1502 | 3 | 3.875 | 2 | 0 | 38.77 | 6 | 3 | 22 | 0 |
| TCMC2507 | C20H25NO3 | Brachyamide B | 327.18 | -0.7262 | 3.22 | 5.013 | 2 | 0 | 38.77 | 8 | 3 | 24 | 1 |
| TCMC2597 | C14H23NO | Sarmentine | 221.18 | -0.9158 | 2.78 | 4.039 | 2 | 0 | 20.31 | 8 | 1 | 16 | 0 |
| TCMC2716 | C26H37NO3 | Brachystamide B | 411.28 | 0.0559 | 3.88 | 8.831 | 2 | 1 | 51.05 | 17 | 2 | 30 | 2 |
Download Data
All data can be downloaded by:→ Selecting data type in the below download table
→ Then click the download button.
