Description of the Component
Component ID |
TCMH2218 |
Latin Name |
Rubia cordifolia |
English Name |
NA |
Chinese Pinyin Name |
Qian Cao Teng |
中文名 |
茜草藤 |
TCM Properties |
|
TCM Meridians |
|
Therapeutic Class English |
|
Therapeutic Class Chinese |
|
Functions |
|
Toxicity |
NA |
Geo-authentic habitats (道地产区) |
NA |
Reference |
Chinese Pharmacopoeia (2015) |
Barcode ID |
GBVX6372-15, GBVX6011-15 |
Barcode Source |
BOLDSYSTEMS |
TCM Prescriptions with the Component
| Prescription ID | Prescription English Name | Prescription Chinese Name |
|---|---|---|
| TCMF6940 | Er Xie Ting Granules | 儿泻停颗粒 |
Targeted Human Proteins by the Ingredient of Component
| Target ID | Gene Symbol | Target Name | Target Class | Uniprot ID |
|---|---|---|---|---|
| TCMT1 | EHMT2 | Histone-lysine N-methyltransferase, H3 lysine-9 specific 3 | Transferase | Q96KQ7 |
| TCMT101 | PTPN1 | Protein-tyrosine phosphatase 1B | Hydrolase | P18031 |
| TCMT102 | ACP1 | Low molecular weight phosphotyrosine protein phosphatase | Hydrolase | P24666 |
| TCMT103 | PTPRF | Receptor-type tyrosine-protein phosphatase F (LAR) | Hydrolase | P10586 |
| TCMT11 | HIF1A | Hypoxia-inducible factor 1 alpha | Transcription factor | Q16665 |
| TCMT125 | GBA | Beta-glucocerebrosidase | Hydrolase | P04062 |
| TCMT126 | TERT | Telomerase reverse transcriptase | Transferase | O14746 |
| TCMT13 | APEX1 | DNA-(apurinic or apyrimidinic site) lyase | Lyase | P27695 |
| TCMT130 | ALOX5 | Arachidonate 5-lipoxygenase | Oxidoreductase | P09917 |
| TCMT131 | ACHE | Acetylcholinesterase | Hydrolase | P22303 |
| TCMT132 | BCHE | Butyrylcholinesterase | Hydrolase | P06276 |
| TCMT133 | CA1 | Carbonic anhydrase I | Lyase | P00915 |
| TCMT134 | CA2 | Carbonic anhydrase II | Lyase | P00918 |
| TCMT135 | CA14 | Carbonic anhydrase XIV | Lyase | Q9ULX7 |
| TCMT136 | CA12 | Carbonic anhydrase XII | Lyase | O43570 |
| TCMT137 | CA9 | Carbonic anhydrase IX | Lyase | Q16790 |
| TCMT138 | CA7 | Carbonic anhydrase VII | Lyase | P43166 |
| TCMT139 | CA6 | Carbonic anhydrase VI | Lyase | P23280 |
| TCMT140 | CA5B | Carbonic anhydrase VB | Lyase | Q9Y2D0 |
| TCMT141 | CA5A | Carbonic anhydrase VA | Lyase | P35218 |
| TCMT142 | CA4 | Carbonic anhydrase IV | Lyase | P22748 |
| TCMT143 | CA3 | Carbonic anhydrase III | Lyase | P07451 |
| TCMT150 | RORC | Nuclear receptor ROR-gamma | Nuclear receptor | P51449 |
| TCMT156 | CYP19A1 | Cytochrome P450 19A1 | Oxidoreductase | P11511 |
| TCMT158 | EPHX2 | Epoxide hydratase | Lyase | P34913 |
| TCMT159 | TYR | Tyrosinase | Oxidoreductase | P14679 |
| TCMT162 | UGT1A1 | UDP-glucuronosyltransferase 1-1 | Transferase | P22309 |
| TCMT164 | PTGS1 | Cyclooxygenase-1 | Oxidoreductase | P23219 |
| TCMT17 | POLB | DNA polymerase beta | Transferase | P06746 |
| TCMT171 | PTPN6 | Protein-tyrosine phosphatase 1C | Hydrolase | P29350 |
| TCMT18 | GAA | Lysosomal alpha-glucosidase | Hydrolase | P10253 |
| TCMT186 | MAOB | Monoamine oxidase B | Oxidoreductase | P27338 |
| TCMT190 | PTPN2 | T-cell protein-tyrosine phosphatase | Hydrolase | P17706 |
| TCMT193 | RELA | Nuclear factor NF-kappa-B p65 subunit | Transcription factor | Q04206 |
| TCMT2 | MAPT | Microtubule-associated protein tau | Unclassified | P10636 |
| TCMT208 | MAOA | Monoamine oxidase A | Oxidoreductase | P21397 |
| TCMT214 | MGLL | Monoglyceride lipase | Unclassified | Q99685 |
| TCMT215 | CYP1A1 | Cytochrome P450 1A1 | Oxidoreductase | P04798 |
| TCMT221 | ABCB11 | Bile salt export pump | Transporter | O95342 |
| TCMT223 | AKR1B1 | Aldose reductase | Oxidoreductase | P15121 |
| TCMT225 | CA13 | Carbonic anhydrase XIII | Lyase | Q8N1Q1 |
| TCMT232 | ABCB1 | P-glycoprotein 1 | Transporter | P08183 |
| TCMT233 | PTPN11 | Protein-tyrosine phosphatase 2C | Hydrolase | Q06124 |
| TCMT236 | ESR2 | Estrogen receptor beta | Nuclear receptor | Q92731 |
| TCMT248 | CXCL8 | Interleukin-8 | Unclassified | P10145 |
| TCMT257 | CYP1B1 | Cytochrome P450 1B1 | Oxidoreductase | Q16678 |
| TCMT261 | DAPK1 | Death-associated protein kinase 1 | Kinase | P53355 |
| TCMT273 | NR1H4 | Bile acid receptor FXR | Nuclear receptor | Q96RI1 |
| TCMT280 | AKR1B10 | Aldo-keto reductase family 1 member B10 | Oxidoreductase | O60218 |
| TCMT281 | DPP4 | Dipeptidyl peptidase IV | Unclassified | P27487 |
| TCMT295 | MMP1 | Matrix metalloproteinase-1 | Hydrolase | P03956 |
| TCMT3 | ALOX15 | Arachidonate 15-lipoxygenase | Oxidoreductase | P16050 |
| TCMT30 | PTGS2 | Cyclooxygenase-2 | Oxidoreductase | P35354 |
| TCMT306 | MMP2 | Matrix metalloproteinase-2 | Hydrolase | P08253 |
| TCMT31 | CYP2C19 | Cytochrome P450 2C19 | Oxidoreductase | P33261 |
| TCMT320 | MMP3 | Matrix metalloproteinase 3 | Hydrolase | P08254 |
| TCMT321 | MMP9 | Matrix metalloproteinase 9 | Hydrolase | P14780 |
| TCMT327 | TRPV1 | Vanilloid receptor | Ion channel | Q8NER1 |
| TCMT329 | NQO2 | Quinone reductase 2 | Oxidoreductase | P16083 |
| TCMT33 | CYP3A4 | Cytochrome P450 3A4 | Oxidoreductase | P08684 |
| TCMT336 | IDO1 | Indoleamine 2,3-dioxygenase | Oxidoreductase | P14902 |
| TCMT34 | CYP2D6 | Cytochrome P450 2D6 | Oxidoreductase | P10635 |
| TCMT41 | IDH1 | Isocitrate dehydrogenase [NADP] cytoplasmic | Oxidoreductase | O75874 |
| TCMT45 | APP | Beta amyloid A4 protein | Unclassified | P05067 |
| TCMT558 | TOP2A | DNA topoisomerase II alpha | Isomerase | P11388 |
| TCMT563 | CDC25B | Dual specificity phosphatase Cdc25B | Hydrolase | P30305 |
| TCMT564 | PRMT1 | Protein-arginine N-methyltransferase 1 | Transferase | Q99873 |
| TCMT566 | NOS2 | Nitric oxide synthase, inducible | Oxidoreductase | P35228 |
| TCMT59 | BCL2L1 | Apoptosis regulator Bcl-X | Ion channel | Q07817 |
| TCMT598 | TOP1 | DNA topoisomerase I | Isomerase | P11387 |
| TCMT6 | NFKB1 | Nuclear factor NF-kappa-B p105 subunit | Transcription factor | P19838 |
| TCMT601 | F2 | Thrombin | Unclassified | P00734 |
| TCMT609 | CTSL | Cathepsin L | Unclassified | P07711 |
| TCMT629 | ABCC1 | Multidrug resistance-associated protein 1 | Transporter | P33527 |
| TCMT640 | CTSD | Cathepsin D | Unclassified | P07339 |
| TCMT69 | THRB | Thyroid hormone receptor beta-1 | Nuclear receptor | P10828 |
| TCMT714 | ODC1 | Ornithine decarboxylase | Lyase | P11926 |
| TCMT726 | BCR | Bcr/Abl fusion protein | Kinase | P11274 |
| TCMT729 | PIK3CA | PI3-kinase p110-alpha subunit | Transferase | P42336 |
| TCMT730 | PIK3CB | PI3-kinase p110-beta subunit | Transferase | P42338 |
| TCMT747 | ABCG2 | ATP-binding cassette sub-family G member 2 | Transporter | Q9UNQ0 |
| TCMT8 | KDM4E | Lysine-specific demethylase 4D-like | Oxidoreductase | B2RXH2 |
| TCMT80 | MAPK1 | MAP kinase ERK2 | Kinase | P28482 |
| TCMT81 | ALOX12 | Arachidonate 12-lipoxygenase | Oxidoreductase | P18054 |
| TCMT82 | ESR1 | Estrogen receptor alpha | Nuclear receptor | P03372 |
| TCMT83 | CD38 | Lymphocyte differentiation antigen CD38 | Unclassified | P28907 |
| TCMT87 | CYP2C9 | Cytochrome P450 2C9 | Oxidoreductase | P11712 |
Targeted Pathogenic Microbes by the Ingredient of Component
| Target ID | Target Name |
|---|---|
| TCMT1099 | Neuraminidase |
| TCMT1104 | Sortase |
| TCMT1107 | Protease |
| TCMT1112 | Quinolone resistance protein norA |
| TCMT1170 | Enterobacter cloacae |
| TCMT1176 | Streptococcus pneumoniae |
| TCMT1178 | Actinomyces viscosus |
| TCMT1182 | Streptococcus sanguinis |
| TCMT1185 | Mycobacterium phlei |
| TCMT1189 | Pseudomonas fluorescens |
| TCMT1212 | Verticillium dahliae |
| TCMT1213 | Neisseria gonorrhoeae |
| TCMT1218 | Staphylococcus aureus |
| TCMT1222 | Plasmodium falciparum D6 |
| TCMT1226 | Klebsiella pneumoniae |
| TCMT1229 | Enterococcus faecalis |
| TCMT1232 | Pseudomonas aeruginosa |
| TCMT1246 | Escherichia coli |
| TCMT1248 | Hepatitis C virus |
| TCMT1251 | Candida albicans |
| TCMT1255 | Human immunodeficiency virus 1 |
| TCMT1289 | Shigella dysenteriae |
| TCMT1438 | Plasmodium falciparum |
| TCMT1454 | Bacillus subtilis |
| TCMT1455 | Mycobacterium tuberculosis H37Rv |
| TCMT1458 | Filobasidiella neoformans |
| TCMT1462 | Streptococcus mutans |
| TCMT1463 | Mycobacterium tuberculosis |
| TCMT1464 | Hepatitis B virus |
| TCMT1465 | Entamoeba histolytica |
Ingredient Structrues
Ingredient ID: TCMC995
Formula: C35H60O6
Ingredient ID: TCMC984
Formula: C21H20O9
Ingredient ID: TCMC921
Formula: C14H12O3
Ingredient ID: TCMC913
Formula: C15H14O6
Ingredient ID: TCMC880
Formula: C6H6O2
Ingredient ID: TCMC801
Formula: C29H50O
Ingredient ID: TCMC741
Formula: C14H8O4
Ingredient ID: TCMC618
Formula: C32H50O4
Ingredient ID: TCMC3
Formula: C15H14O6
Ingredient ID: TCMC2813
Formula: C17H16O4
Ingredient ID: TCMC277
Formula: C15H10O4
Ingredient ID: TCMC2694
Formula: C20H24O6
Ingredient ID: TCMC2569
Formula: C14H10O4
Ingredient ID: TCMC2533
Formula: C17H18O4
Ingredient ID: TCMC2411
Formula: C30H48O3
Ingredient ID: TCMC2348
Formula: C20H28O6
Ingredient ID: TCMC2051
Formula: C10H8O4
Ingredient ID: TCMC2031
Formula: C27H30O16
Ingredient ID: TCMC2003
Formula: C14H12O3
Ingredient ID: TCMC1977
Formula: C6H6O3
Ingredient ID: TCMC1976
Formula: C8H11NO3
Ingredient ID: TCMC1967
Formula: C14H8O5
Ingredient ID: TCMC1904
Formula: C17H19NO3
Ingredient ID: TCMC1889
Formula: C16H12O5
Ingredient ID: TCMC1786
Formula: C30H48O3
Ingredient ID: TCMC1002
Formula: C15H12O3
Properties
| Ingredient ID | Formulae | Name | MW | AlogP | MlogP | XlogP | # HBA | # HBD | PSA | # Rotatable Bond | # Ring | # Heacy Atom | Lipinski RO5 Violation |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| TCMC3 | C15H14O6 | (-)-Catechin | 290.08 | -2.494 | 2.45 | 0.406 | 1 | 5 | 110.38 | 6 | 3 | 21 | 0 |
| TCMC277 | C15H10O4 | 1-Hydroxy-2-Methoxyanthracene-9,10-Dione | 254.06 | -1.0397 | 2.67 | 2.245 | 2 | 1 | 63.6 | 3 | 3 | 19 | 0 |
| TCMC618 | C32H50O4 | Acetyl Oleanolic Acid | 498.37 | 2.5089 | 4.54 | 9.792 | 4 | 1 | 63.6 | 12 | 5 | 36 | 1 |
| TCMC741 | C14H8O4 | Athraquinones A | 240.04 | -1.4482 | 2.56 | 2.155 | 2 | 2 | 74.6 | 2 | 3 | 18 | 0 |
| TCMC801 | C29H50O | Beta-Sitosterol | 414.39 | 1.3 | 4.54 | 11.595 | 1 | 1 | 20.23 | 13 | 4 | 30 | 1 |
| TCMC880 | C6H6O2 | Catechol | 110.04 | -0.9206 | 1.9 | 1.299 | 0 | 2 | 40.46 | 2 | 1 | 8 | 0 |
| TCMC913 | C15H14O6 | Cianidanol | 290.08 | -2.494 | 2.45 | 0.406 | 1 | 5 | 110.38 | 6 | 3 | 21 | 0 |
| TCMC921 | C14H12O3 | Cis-Resveratrol | 228.08 | -0.9131 | 2.67 | 3.436 | 0 | 3 | 60.69 | 5 | 2 | 17 | 0 |
| TCMC984 | C21H20O9 | Daidzin | 416.11 | -3.3342 | 2.78 | 1.367 | 6 | 5 | 145.91 | 9 | 4 | 30 | 0 |
| TCMC995 | C35H60O6 | Daucosterol | 576.44 | -0.4469 | 4.65 | 10.487 | 6 | 4 | 99.38 | 19 | 5 | 41 | 1 |
| TCMC1002 | C15H12O3 | Dehydro-Alpha-Lapachone | 240.08 | 0.2056 | 2.78 | 3.044 | 3 | 0 | 43.37 | 2 | 3 | 18 | 0 |
| TCMC1786 | C30H48O3 | Oleanolic_Acid | 456.36 | 2.1298 | 4.43 | 9.052 | 3 | 2 | 57.53 | 10 | 5 | 33 | 1 |
| TCMC1889 | C16H12O5 | Physcion | 284.07 | -0.858 | 2.67 | 1.183 | 2 | 2 | 83.83 | 5 | 3 | 21 | 0 |
| TCMC1904 | C17H19NO3 | Piperine | 285.14 | -0.9494 | 2.89 | 3.167 | 2 | 0 | 38.77 | 4 | 3 | 21 | 0 |
| TCMC1967 | C14H8O5 | Purpurin | 256.04 | -1.9085 | 2.45 | 1.192 | 2 | 3 | 94.83 | 3 | 3 | 19 | 0 |
| TCMC1976 | C8H11NO3 | Pyridoxine | 169.07 | -0.9182 | 1.9 | -0.677 | 3 | 3 | 73.58 | 6 | 1 | 12 | 0 |
| TCMC1977 | C6H6O3 | Pyrogallol | 126.03 | -1.3809 | 1.79 | 0.765 | 0 | 3 | 60.69 | 3 | 1 | 9 | 0 |
| TCMC2003 | C14H12O3 | Resveratrol | 228.08 | -0.9131 | 2.67 | 3.436 | 0 | 3 | 60.69 | 5 | 2 | 17 | 0 |
| TCMC2031 | C27H30O16 | Rutin | 610.15 | -6.139 | 2.67 | -1.188 | 11 | 10 | 265.52 | 17 | 5 | 43 | 2 |
| TCMC2051 | C10H8O4 | Scopoletin | 192.04 | -0.2421 | 2.12 | 1.088 | 1 | 1 | 55.76 | 3 | 2 | 14 | 0 |
| TCMC2348 | C20H28O6 | Oridonin | 364.19 | -1.9745 | 3 | 0.248 | 6 | 4 | 107.22 | 6 | 3 | 26 | 0 |
| TCMC2411 | C30H48O3 | Epi-Oleanolic Acid | 456.36 | 2.1298 | 4.43 | 9.052 | 3 | 2 | 57.53 | 10 | 5 | 33 | 1 |
| TCMC2533 | C17H18O4 | Dihydromollugin | 286.12 | 0.3089 | 2.89 | 4.456 | 2 | 1 | 55.76 | 6 | 3 | 21 | 0 |
| TCMC2569 | C14H10O4 | Furomollugin | 242.06 | -0.6032 | 2.56 | 3.467 | 2 | 1 | 59.67 | 4 | 3 | 18 | 0 |
| TCMC2694 | C20H24O6 | Isolariciresinol | 360.16 | -2.2141 | 3 | 1.061 | 2 | 4 | 99.38 | 11 | 3 | 26 | 0 |
| TCMC2813 | C17H16O4 | Mollugin | 284.1 | 0.4587 | 2.89 | 4.265 | 2 | 1 | 55.76 | 6 | 3 | 21 | 0 |
Download Data
All data can be downloaded by:→ Selecting data type in the below download table
→ Then click the download button.
