Description of the Component
Component ID |
TCMH1703 |
Latin Name |
Swertia mileensis |
English Name |
Mileen swertia |
Chinese Pinyin Name |
Qing Ye Dan |
中文名 |
é’å¶èƒ† |
TCM Properties |
Cold,Sweet,Bitter |
TCM Meridians |
Bladder,Liver,Gallbladder |
Therapeutic Class English |
|
Therapeutic Class Chinese |
|
Functions |
increase the flow of bile, and remove heat and damp |
Toxicity |
NA |
Geo-authentic habitats (道地产区) |
NA |
Reference |
Chinese Pharmacopoeia (2015) |
Barcode ID |
DQ317486 |
Barcode Source |
GenBank |
TCM Prescriptions with the Component
| Prescription ID | Prescription English Name | Prescription Chinese Name |
|---|---|---|
| TCMF997 | Huang Dan Gan Yan Pills | 黄疸è‚炎丸 |
| TCMF4011 | Huang Dan Gan Yan Pills | 黄疸è‚炎丸 |
| TCMFx664 | Qing Ye Dan Tablet | é’å¶èƒ†ç‰‡ |
| TCMFx1388 | Shisanwei Bangga Powder | å三味榜嘎散 |
| TCMFx2422 | Shisanwei Bangga Powder | å三味榜嘎散 |
Targeted Human Proteins by the Ingredient of Component
| Target ID | Gene Symbol | Target Name | Target Class | Uniprot ID |
|---|---|---|---|---|
| TCMT101 | PTPN1 | Protein-tyrosine phosphatase 1B | Hydrolase | P18031 |
| TCMT102 | ACP1 | Low molecular weight phosphotyrosine protein phosphatase | Hydrolase | P24666 |
| TCMT103 | PTPRF | Receptor-type tyrosine-protein phosphatase F (LAR) | Hydrolase | P10586 |
| TCMT171 | PTPN6 | Protein-tyrosine phosphatase 1C | Hydrolase | P29350 |
| TCMT190 | PTPN2 | T-cell protein-tyrosine phosphatase | Hydrolase | P17706 |
| TCMT214 | MGLL | Monoglyceride lipase | Unclassified | Q99685 |
| TCMT223 | AKR1B1 | Aldose reductase | Oxidoreductase | P15121 |
| TCMT233 | PTPN11 | Protein-tyrosine phosphatase 2C | Hydrolase | Q06124 |
| TCMT273 | NR1H4 | Bile acid receptor FXR | Nuclear receptor | Q96RI1 |
| TCMT280 | AKR1B10 | Aldo-keto reductase family 1 member B10 | Oxidoreductase | O60218 |
| TCMT41 | IDH1 | Isocitrate dehydrogenase [NADP] cytoplasmic | Oxidoreductase | O75874 |
| TCMT558 | TOP2A | DNA topoisomerase II alpha | Isomerase | P11388 |
| TCMT563 | CDC25B | Dual specificity phosphatase Cdc25B | Hydrolase | P30305 |
| TCMT566 | NOS2 | Nitric oxide synthase, inducible | Oxidoreductase | P35228 |
| TCMT598 | TOP1 | DNA topoisomerase I | Isomerase | P11387 |
Targeted Pathogenic Microbes by the Ingredient of Component
| Target ID | Target Name |
|---|---|
| TCMT1107 | Protease |
| TCMT1178 | Actinomyces viscosus |
| TCMT1229 | Enterococcus faecalis |
| TCMT1248 | Hepatitis C virus |
| TCMT1255 | Human immunodeficiency virus 1 |
| TCMT1462 | Streptococcus mutans |
| TCMT1463 | Mycobacterium tuberculosis |
Ingredient Structrues
Ingredient ID: TCMC3909
Formula: C22H22O11
Ingredient ID: TCMC3590
Formula: C16H22O9
Ingredient ID: TCMC1786
Formula: C30H48O3
Properties
| Ingredient ID | Formulae | Name | MW | AlogP | MlogP | XlogP | # HBA | # HBD | PSA | # Rotatable Bond | # Ring | # Heacy Atom | Lipinski RO5 Violation |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| TCMC1786 | C30H48O3 | Oleanolic_Acid | 456.36 | 2.1298 | 4.43 | 9.052 | 3 | 2 | 57.53 | 10 | 5 | 33 | 1 |
| TCMC3590 | C16H22O9 | Sweroside | 358.1263823 | -2.8201 | 2.23 | -0.256 | 9 | 4 | 131.67 | 4 | 3 | 25 | 0 |
| TCMC3909 | C22H22O11 | Swertiajaponin | 462.1162115 | -3.9796 | 2.67 | -0.94 | 9 | 7 | 177.14 | 4 | 4 | 33 | 1 |
Download Data
All data can be downloaded by:→ Selecting data type in the below download table
→ Then click the download button.
