Component: Gentiana macrophylla 秦艽


Description of the Component

Component ID
TCMH1673
Latin Name
Gentiana macrophylla
English Name
large-leaved gentian
Chinese Pinyin Name
Qin Jiao
中文名
秦艽
TCM Properties
Minor cold,Pungent,Bitter
TCM Meridians
Stomach,Liver,Gallbladder
Therapeutic Class English
For dispelling wind-dampness
Therapeutic Class Chinese
祛风湿
Functions
relieve rheumatic conditions, and remove damp-heat
Toxicity
NA
Geo-authentic habitats (道地产区)
Gansu Province
Reference
Chinese Pharmacopoeia (2015)
Barcode ID
ITSAO2245-14
Barcode Source
BOLDSYSTEMS

TCM Prescriptions with the Component

Prescription ID Prescription English Name Prescription Chinese Name
TCMF7259 秦艽鳖甲散
TCMFx2918 An Kun Zan Yu Pills 安坤赞育丸
TCMF2963 An Yang Hu Gu Yao Wine 安阳虎骨药酒
TCMF3002 Bai Feng Yin 白凤饮
TCMFx3509 Bao Gu Mu Gua Wine 豹骨木瓜酒
TCMF3501 Bao Gu Wine 豹骨酒
TCMF2514 Blood Tonification and Wind Dispersing Decoction 养血祛风汤
TCMF2843 Da Qin Jiao Decoction 大秦艽汤
TCMF2465 Decoction for Relieving Pantalgia due to Blood Stagnation 身痛逐瘀汤
TCMF2581 Decoction of Gentianae Macrophyllae 大秦艽汤
TCMFx2400 Detoxification and Yellowness Removing Decoction 解毒退黄汤
TCMF3355 Die Da Feng Shi Yao Wine 跌打风湿药酒
TCMF7300 Du Huo Ji Sheng Decoction 独活寄生汤
TCMF828 Du Huo Ji Sheng Pills 独活寄生丸
TCMF3704 Du Huo Ji Sheng Pills 独活寄生丸
TCMF3696 Du Huo Ji Sheng Recipe 独活寄生合剂
TCMF829 Du Huo Ji Sheng Recipe 独活寄生合剂
TCMF3807 Du Zhong Zhuang Gu Capsules 杜仲壮骨胶囊
TCMF3815 Du Zhong Zhuang Gu Pills 杜仲壮骨丸
TCMF2562 Duhuo Jisheng Decoction 独活寄生汤
TCMF3424 Feng Shi Han Tong Tablets 风湿寒痛片
TCMF3530 Feng Shi Oral Liquid 风湿液
TCMF3432 Feng Shi Wine 风湿酒
TCMF3548 Feng Shi Zhen Tong Pills 风湿镇痛丸
TCMF3598 Feng Tong Pills 风痛丸
TCMF3756 Fu Bao Jin Pills 妇宝金丸
TCMFx3150 Fu Fang Xia Tian Wu Tablets 复方夏天无片
TCMF3837 Fu Ke Bai Feng Oral Liquid 妇科白凤口服液
TCMF3845 Fu Ke Bai Feng Tablets 妇科白凤片
TCMFx3417 Gu Ci Pills 骨刺丸
TCMFx3425 Gu Ci Xiao Tong Capsules 骨刺消痛胶囊
TCMFx748 Gu Ci Xiao Tong Tablet 骨刺消痛片
TCMFx3433 Gu Ci Xiao Tong Tablets 骨刺消痛片
TCMF3458 Gu Jin Pills 骨筋丸
TCMF3466 Gu Jin Wan Capsules 骨筋丸胶囊
TCMF3473 Gu Jin Wan Tablets 骨筋丸片
TCMF3669 Guan Jie Feng Tong Pills 关节风痛丸
TCMF3686 Guan Jie Ke Bi Pills 关节克痹丸
TCMF3703 Guan Jie Zhen Tong Ointment 关节镇痛膏
TCMF2348 Headach Syrup 头痛定糖浆
TCMF4497 Hong Mao Yao Wine 鸿茅药酒
TCMFx4695 Hu Gu Zhui Feng Wine 虎骨追风酒
TCMF4394 Huo Xue Shu Jin Ding 活血舒筋酊
TCMFx2046 Hyperthermia Cooling Powder 清骨散
TCMF4641 Ji Gan Tui Huang Capsules 急肝退黄胶囊
TCMF39 Ji Sheng Zhui Feng Liquor 寄生追风酒
TCMF4687 Ji Sheng Zhui Feng Oral Liquid 寄生追风液
TCMF4920 Jian Bu Qiang Shen Pills 健步强身丸
TCMF4929 Jian Bu Zhuang Gu Pills 健步壮骨丸
TCMF4284 Jin Gu Ning Cha Ji 筋骨宁搽剂
TCMF4299 Jin Gu Teng Tong Wine 筋骨疼痛酒
TCMF7155 Jin Gu Tong Xiao Pills 筋骨痛消丸
TCMF4032 Jin Mao Gou Ji Pills 金毛狗脊丸
TCMF4466 Jing Fu Kang Granules 颈复康颗粒
TCMF1091 Jing Fu Kang Granules 颈复康颗粒
TCMF4557 Jiu Zhi Xi Xian Cao Yao Wine 九制豨莶草药酒
TCMF2868 Juan Bi Decoction 蠲痹汤
TCMF4244 Ling Long Gan Mao Capsules 灵龙感冒胶囊
TCMF4756 Lu Jin Zhuang Gu Wine 鹿筋壮骨酒
TCMF4590 Mu Gua Wine 木瓜酒
TCMFx4456 Pan Long Qi Tablets 盘龙七片
TCMFx4463 Pan Long Qi Yao Wine 盘龙七药酒
TCMF4601 Pian Tan Fu Yuan Pills 偏瘫复元丸
TCMF2538 Powder of Astragali seu Hedysari and Carapax Trionycis 黄芪鳖甲散
TCMF2583 Powder of Ginseng and Astragali seu Hedysari 人参黄芪散
TCMF2226 Powder of Two Effective Ingredients with Cyperus Peel and Perilla Leaf 加味香苏散
TCMFx4868 Qi She Yao Wine 蕲蛇药酒
TCMFx4874 Qi She Zhui Feng Wine 蕲蛇追风酒
TCMF5087 Qiang Gan Pills 强肝丸
TCMF5079 Qiang Gan Syrup 强肝糖浆
TCMF4977 Qiang Shen Zhuang Gu Wine 强身壮骨酒
TCMF2318 Qin Jiu Turtle Shell Decoction 秦艽鳖甲饮
TCMF2858 Qing Gu Powder 清骨散
TCMFx5109 Qu Feng Chu Shi Yao Wine 祛风除湿药酒
TCMF5093 Qu Feng Oral Liquid 驱风液
TCMF5062 Qu Feng She Wine 驱风蛇酒
TCMF1431 Qufeng Shujin Pills 祛风舒筋丸
TCMF2606 Qufeng Shujin Pills 祛风舒筋丸
TCMFx2411 Radix Bupleuri Bone Soothing Powder 柴胡清骨散
TCMF7057 Run Tong Pills 润通丸
TCMF2833 San Bi Decoction 三痹汤
TCMF7299 San Bi Decoction 三痹汤
TCMF5208 San Feng Huo Xue Ointment 散风活血膏
TCMF5193 San Yu Shen Qu 三余神曲
TCMFx5703 Shang Ke Zhuang Gu Ointment 伤科壮骨膏
TCMFx5047 She Yao Pills 蛇咬丸
TCMFx3204 Shen Gui Lu Rong Pills 参桂鹿茸丸
TCMF3605 Shen Rong Mu Gua Yao Wine 参茸木瓜药酒
TCMF2881 Shen Tong Zhu Yu Decoction 身痛逐瘀汤
TCMFx2488 Shi Guo Gong's Prescription for Preparing Medicated Wine
TCMF5589 Shu Feng Huo Luo Pills 疏风活络丸
TCMF5582 Shu Feng Huo Luo Tablets 疏风活络片
TCMF1145 Shu Feng Huo Luo Pills 疏风活络丸
TCMFx5605 Shu Feng Zai Zao Pills 疏风再造丸
TCMF5478 Shu Luo Yang Gan Pills 舒络养肝丸
TCMFx5764 Shui Peng Ointment 水蓬膏
TCMFx2236 Soothing Drink 疏凿饮子
TCMFx5473 Tian Ma Zhui Feng Ointment 天麻追风膏
TCMF1100 Tong Feng Ding Capsule 痛风定胶囊
TCMF5133 Tou Feng Ointment 头风膏
TCMFx5284 Wai Yong Wan Ying Ointment 外用万应膏
TCMFx5293 Wai Yong Wu Di Ointment 外用无敌膏
TCMFx2433 Waist Strengthening Decoction
TCMF5331 Wu Di Yao Wine 无敌药酒
TCMFx149 Xi Xian Tong Shuan Capsule 豨莶通栓胶囊
TCMFx148 Xi Xian Tong Shuan Pills 豨莶通栓丸
TCMF6452 Xiao Yu Ding Tong Ointment 消瘀定痛膏
TCMF7399 Xiao Zhi Pills 消痣丸
TCMF6416 Xue Lian Yao Wine 雪莲药酒
TCMF7097 Xue Shan Jin Luo Han Zhi Tong Tu Mo Ji 雪山金罗汉止痛涂膜剂
TCMFx6061 Yang Xue Yu Feng Wine 养血愈风酒
TCMF6178 Yao Zhui Bi Tong Pills 腰椎痹痛丸
TCMF691 Yu Jin Yin Xie Tablet 郁金银屑片
TCMF6465 Yu Jin Yin Xie Tablets 郁金银屑片
TCMFx6310 Zheng Gu Ointment 正骨膏
TCMF6480 Zhuang Gu Mu Gua Wine 壮骨木瓜酒
TCMF6612 Zhui Feng Huo Luo Wine 追风活络酒
TCMF6617 Zhui Feng Huo Xue Ointment 追风活血膏
TCMFx6655 Zhui Feng Tou Gu Pills 追风透骨丸
TCMFx820 Zhui Feng Tou Gu Pills 追风透骨丸
TCMFx6648 Zhui Feng Tou Gu Tablets 追风透骨片

Targeted Human Proteins by the Ingredient of Component

Target ID Gene Symbol Target Name Target Class Uniprot ID
TCMT101 PTPN1 Protein-tyrosine phosphatase 1B Hydrolase P18031
TCMT102 ACP1 Low molecular weight phosphotyrosine protein phosphatase Hydrolase P24666
TCMT103 PTPRF Receptor-type tyrosine-protein phosphatase F (LAR) Hydrolase P10586
TCMT132 BCHE Butyrylcholinesterase Hydrolase P06276
TCMT164 PTGS1 Cyclooxygenase-1 Oxidoreductase P23219
TCMT171 PTPN6 Protein-tyrosine phosphatase 1C Hydrolase P29350
TCMT190 PTPN2 T-cell protein-tyrosine phosphatase Hydrolase P17706
TCMT214 MGLL Monoglyceride lipase Unclassified Q99685
TCMT223 AKR1B1 Aldose reductase Oxidoreductase P15121
TCMT232 ABCB1 P-glycoprotein 1 Transporter P08183
TCMT233 PTPN11 Protein-tyrosine phosphatase 2C Hydrolase Q06124
TCMT273 NR1H4 Bile acid receptor FXR Nuclear receptor Q96RI1
TCMT280 AKR1B10 Aldo-keto reductase family 1 member B10 Oxidoreductase O60218
TCMT281 DPP4 Dipeptidyl peptidase IV Unclassified P27487
TCMT30 PTGS2 Cyclooxygenase-2 Oxidoreductase P35354
TCMT301 PTGES Prostaglandin E synthase Isomerase O14684
TCMT33 CYP3A4 Cytochrome P450 3A4 Oxidoreductase P08684
TCMT34 CYP2D6 Cytochrome P450 2D6 Oxidoreductase P10635
TCMT41 IDH1 Isocitrate dehydrogenase [NADP] cytoplasmic Oxidoreductase O75874
TCMT558 TOP2A DNA topoisomerase II alpha Isomerase P11388
TCMT563 CDC25B Dual specificity phosphatase Cdc25B Hydrolase P30305
TCMT566 NOS2 Nitric oxide synthase, inducible Oxidoreductase P35228
TCMT598 TOP1 DNA topoisomerase I Isomerase P11387


Targeted Pathogenic Microbes by the Ingredient of Component

Target ID Target Name
TCMT1099 Neuraminidase
TCMT1104 Sortase
TCMT1107 Protease
TCMT1178 Actinomyces viscosus
TCMT1218 Staphylococcus aureus
TCMT1226 Klebsiella pneumoniae
TCMT1229 Enterococcus faecalis
TCMT1232 Pseudomonas aeruginosa
TCMT1246 Escherichia coli
TCMT1248 Hepatitis C virus
TCMT1255 Human immunodeficiency virus 1
TCMT1438 Plasmodium falciparum
TCMT1458 Filobasidiella neoformans
TCMT1462 Streptococcus mutans
TCMT1463 Mycobacterium tuberculosis
TCMT1465 Entamoeba histolytica

Ingredient Structrues

Ingredient ID: TCMC995
Formula: C35H60O6

Ingredient ID: TCMC801
Formula: C29H50O

Ingredient ID: TCMC7310
Formula: C10H8O4

Ingredient ID: TCMC6885
Formula: C33H57NO3

Ingredient ID: TCMC5947
Formula: C30H48O2

Ingredient ID: TCMC5857
Formula: C26H30O6

Ingredient ID: TCMC5504
Formula: C22H30O14

Ingredient ID: TCMC5473
Formula: C25H34O14

Ingredient ID: TCMC5467
Formula: C19H24O9

Ingredient ID: TCMC4720
Formula: C13H14O4

Ingredient ID: TCMC3783
Formula: C9H9NO2

Ingredient ID: TCMC3780
Formula: C10H9NO2

Ingredient ID: TCMC3710
Formula: C10H8O3

Ingredient ID: TCMC348
Formula: C27H44O7

Ingredient ID: TCMC3305
Formula: C16H20O9

Ingredient ID: TCMC3186
Formula: C29H58O2

Ingredient ID: TCMC2681
Formula: C17H26O10

Ingredient ID: TCMC2661
Formula: C16H24O10

Ingredient ID: TCMC2233
Formula: C21H20O10

Ingredient ID: TCMC1786
Formula: C30H48O3

Ingredient ID: TCMC1502
Formula: C34H46O18

Ingredient ID: TCMC1403
Formula: C21H20O11

Properties

Ingredient ID Formulae Name MW AlogP MlogP XlogP # HBA # HBD PSA # Rotatable Bond # Ring # Heacy Atom Lipinski RO5 Violation
TCMC348 C27H44O7 20-Hydroxyecdysone 480.31 -1.1982 3.66 1.049 7 6 138.45 16 4 34 1
TCMC801 C29H50O Beta-Sitosterol 414.39 1.3 4.54 11.595 1 1 20.23 13 4 30 1
TCMC995 C35H60O6 Daucosterol 576.44 -0.4469 4.65 10.487 6 4 99.38 19 5 41 1
TCMC1403 C21H20O11 Isoorientin 448.1 -4.5805 2.56 -1.042 6 8 197.37 11 4 32 1
TCMC1502 C34H46O18 Liriodendrtachioside 742.27 -5.6196 3.22 -1.42 12 8 254.14 24 6 52 3
TCMC1786 C30H48O3 Oleanolic_Acid 456.36 2.1298 4.43 9.052 3 2 57.53 10 5 33 1
TCMC2233 C21H20O10 Vitexin 432.11 -4.1202 2.67 -0.508 6 7 177.14 10 4 31 1
TCMC2661 C16H24O10 Loganic Acid 376.14 -3.1798 2.12 -1.413 10 6 166.14 11 3 26 1
TCMC2681 C17H26O10 Loganin 390.15 -2.9288 2.23 -1.092 10 5 155.14 12 3 27 0
TCMC3186 C29H58O2 Methyl Montanate 438.4436811 -7.1027 4.43 14.719 2 0 26.3 27 0 31 2
TCMC3305 C16H20O9 Gentiopicroside 356.1107322 -2.2256 2.23 -0.314 9 4 131.67 4 3 25 0
TCMC3710 C10H8O3 Erythrocentaurin 176.0473441 -0.0163 2.23 2.053 3 0 43.37 1 2 13 0
TCMC3780 C10H9NO2 Gentianine 175.0633285 0.8836 2.23 1.476 3 0 39.19 1 2 13 0
TCMC3783 C9H9NO2 Gentianidine 163.0633285 0.6156 2.12 1.292 3 0 39.19 0 2 12 0
TCMC4720 C13H14O4 7-Methoxyanofinic Acid 233.0813839 -0.0616 2.45 2.099 2 0 58.59 2 2 17 0
TCMC5467 C19H24O9 Macrophylloside C 396.1420323 -1.2882 2.56 1.274 7 4 134.91 5 3 28 0
TCMC5473 C25H34O14 Macrophylloside D 558.1948558 -3.0351 2.67 -0.263 12 7 214.06 8 4 39 2
TCMC5504 C22H30O14 6'-O-Β-D-Glucopyranosylgentiopicroside 518.1635556 -3.9725 2.34 -1.851 14 7 210.82 7 4 36 2
TCMC5857 C26H30O6 Kurarinone 438.2042387 0.9214 3.66 3.83 1 3 96.22 7 3 32 0
TCMC5947 C30H48O2 Roburic Acid 439.3576057 2.5212 4.54 11.087 2 0 40.13 4 4 32 1
TCMC6885 C33H57NO3 Qinjiaoamide 514.4260197 -8.1135 4.65 14.3 4 1 69.23 27 1 37 2
TCMC7310 C10H8O4 Erythrocentauric Acid 191.0344337 -0.7415 2.12 1.158 4 0 66.43 1 2 14 0

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1. General Information of the Component  
2. TCM Prescriptions with the Component  
3. Putative Targets  
4. Activity & References for Filtering Putative Targets  
5. Ingredient Data & Chemical Structure Information (Properties, InChI, InChIkey, SMILES, etc.)