Component: Lophatherum gracile 淡竹叶


Description of the Component

Component ID
 TCMH420
Latin Name
 Lophatherum gracile
English Name
 Common lophatherum
Chinese Pinyin Name
 Dan Zhu Ye
中文名
 淡竹叶
TCM Properties
 Cold,Sweet,Neutral
TCM Meridians
 Stomach,Small Intestine,Heart
Therapeutic Class English
 Heat clearence
Therapeutic Class Chinese
 清热
Functions
 remove heat, ease the mind and cause diuresis
Toxicity
 NA
Geo-authentic habitats (道地产区)
 Zhejiang Province
Reference
 Chinese Pharmacopoeia (2015)
Barcode ID
 GBVY2724-14, GBVT2442-13
Barcode Source
 BOLDSYSTEMS

TCM Prescriptions with the Component

Prescription ID Prescription English Name Prescription Chinese Name
TCMF2576 Antipyretic and Antitoxic Bolus 清瘟解毒丸
TCMF1339 Antitoxic Bolus of Honeysuckle Flower and Forsythia; Lonicera Poison Relieving Pill 银翘解毒丸
TCMF2241 Decoction of Cephalanoploris 小蓟饮子
TCMFx1839 Decoction of Cortex Poria 茯苓皮汤
TCMF1934 Decoction of lophatheri and Gypsum Fibrosum 竹叶石膏汤
TCMFx2117 Detoxicating Tablet of Rhinoceros Horn and Antelope's Horn 西羚解毒片
TCMFx1191 Dian Xian Kang Capsule 癫痫康胶囊
TCMFx3294 Dian Xian Kang Capsules 癫痫康胶囊
TCMF1952 Exterior Sydrome and Heat Reduction Recipe 解表退热方
TCMF2057 Fire Cathartic Pills 泻青丸
TCMF3135 Fu Fang Xi Ling Jie Du Pills 复方西羚解毒丸
TCMFx3127 Fu Fang Xi Ling Jie Du Tablets 复方西羚解毒片
TCMFx3872 Guang Dong Liang Cha Granules 广东凉茶颗粒
TCMFx3864 Guang Dong Liang Tea 广东凉茶
TCMF2253 Heat Cooling Qi Enhancing Decoction
TCMF2366 Heat Reduction Yin Qiao Powder 退热银翘散
TCMFx4719 Jia Wei Gan Mao Pills 加味感冒丸
TCMF4857 Jia Wei Yin Qiao Tablets 加味银翘片
TCMFx4536 Jiang Ya Ping Tablets 降压平片
TCMF4047 Jin Mei Qing Shu Granules 金梅清暑颗粒
TCMF4093 Jin Qing Gan Mao Granules 金青感冒颗粒
TCMF4099 Jin Qing Jie Du Pills 金青解毒丸
TCMF4377 Jing Ju Gan Mao Tablets 荆菊感冒片
TCMF4459 Jing Zhi Yin Qiao Jie Du Tablets 精制银翘解毒片
TCMF6882 Kou Yan Capsules 口炎胶囊
TCMF6982 Kou Yan Granules 口炎颗粒
TCMFx4547 Kuai Ying Tea 快应茶
TCMF4174 Liang Ge Pills 凉膈丸
TCMF4351 Ling Qiao Jie Du Granules 羚翘解毒颗粒
TCMF4367 Ling Qiao Jie Du Pills 羚翘解毒丸
TCMF4361 Ling Qiao Jie Du Tablets 羚翘解毒片
TCMF4374 Ling Yang Gan Mao Capsules 羚羊感冒胶囊
TCMF4382 Ling Yang Gan Mao Granules 羚羊感冒颗粒
TCMF7055 Ling Yang Gan Mao Oral Liquid 羚羊感冒口服液
TCMF4391 Ling Yang Gan Mao Tablets 羚羊感冒片
TCMFx4475 Liu He Tea 六和茶
TCMF2153 Lonicera Poison Relieving Pills 银翘解毒丸
TCMF2244 Lonicera Powder 银翘散
TCMFx4878 Luo Fu Shan Liang Cha Granules 罗浮山凉茶颗粒
TCMF1320 Pill for Purging Liver Fire; Fire Cathartic Pill 泻青丸
TCMF2526 Poison Eliminating Cooling Decoction 清瘟败毒饮
TCMFx1833 Powder Coicis and Lophatheri 薏苡竹叶散
TCMF2140 Powder for Clearing Away Heat in Upper or Middle Jiao 凉膈散
TCMF1359 Powder of Linicerae and Forsythiae; Lonicera Powder 银翘散
TCMF1649 Promoting Diuresis Powder 导赤散
TCMF5119 Qiang Li Gan Mao Tablets 强力感冒片
TCMFx5381 Qing Liang Fang Shu Infusion 清凉防暑冲剂
TCMFx5577 Qing Re Liang Tea 清热凉茶
TCMF5730 Qing Shu Jie Du Infusion 清暑解毒冲剂
TCMF5779 Qing Wen Jie Du Ointment 清瘟解毒膏
TCMF79 Qing Wen Jie Du Pills 清瘟解毒丸
TCMF5786 Qing Wen Jie Du Tablets 清瘟解毒片
TCMF7394 Qing Xin Li Ge Decoction 清心利膈汤
TCMF5775 Run Fei Zhi Sou Pills 润肺止嗽丸
TCMF960 Run Fei Zhi Sou Pills 润肺止嗽丸
TCMF2229 Saiga Hom Lonicera Poison Relieving Pill 羚翘解毒丸
TCMFx5138 San Ren Recipe 三仁合剂
TCMF5320 Sang Ju Yin Qiao Powder 桑菊银翘散
TCMF3707 Shen Rong Zhui Feng Wine 参茸追风酒
TCMF5512 Shen Shu Infusion 肾舒冲剂
TCMF5153 Shi Yi Qing Wen Pills 时疫清瘟丸
TCMF5597 Shu Feng San Re Capsules 疏风散热胶囊
TCMFx2049 Three Nut Decoction 三仁汤
TCMF5801 Tong Bian Qing Huo Pills 通便清火丸
TCMF2310 Upper Cold Decoction
TCMF1094 Wei C Yin Qiao Tablet 维C银翘片
TCMFx5476 Wei C Yin Qiao Tablets 维C银翘片
TCMFx7212 Wei Cyin Qiao Granules 维C银翘颗粒
TCMFx5490 Wu Li Hui Chun Pills 五粒回春丸
TCMF5758 Xi Ling Jie Du Pills 犀羚解毒丸
TCMF953 Xiao Cuo Pills 消痤丸
TCMF6006 Xiao Cuo Pills 消痤丸
TCMF7098 Xiao Er Feng Re Qing Oral Liquid 小儿风热清口服液
TCMF6934 Xiao Er Feng Re Qing Recipe 小儿风热清合剂
TCMF233 Xiao Er Qi Xing Cha Granules 小儿七星茶颗粒
TCMF6186 Xiao Er Qi Xing Cha Infusion 小儿七星茶冲剂
TCMF232 Xiao Er Qi Xing Cha Oral Liquid 小儿七星茶口服液
TCMF6193 Xiao Er Qi Xing Cha Syrup 小儿七星茶糖浆
TCMFx6285 Xiao Er Qing Re Hua Tan Shuan 小儿清热化痰栓
TCMF6371 Xiao Er Tui Re Granules 小儿退热颗粒
TCMF267 Xiao Er Tui Re Granules 小儿退热颗粒
TCMF6378 Xiao Er Tui Re Oral Liquid 小儿退热口服液
TCMF42 Xiao Er Tui Re Recipe 小儿退热合剂
TCMF6740 Xie Re Recipe 泻热合剂
TCMFx382 Xin Nao Jing Tablet 心脑静片
TCMFx6836 Xin Nao Jing Tablets 心脑静片
TCMF6107 Yin Qiao Dai Pao Ji 银翘袋泡剂
TCMF6131 Yin Qiao Jie Du Granules 银翘解毒颗粒
TCMF6147 Yin Qiao Jie Du Oral Liquid 银翘解毒液
TCMF6139 Yin Qiao Jie Du Pills 银翘解毒丸
TCMF6123 Yin Qiao Jie Du Recipe 银翘解毒合剂
TCMF6155 Yin Qiao Powder 银翘散
TCMF7356 Yin Qiao Powder 银翘散
TCMF6115 Yin Qiao Recipe 银翘合剂
TCMF1028 Yin Qiao Shang Feng Capsule 银翘伤风胶囊
TCMF6162 Yin Qiao Shang Feng Capsules 银翘伤风胶囊
TCMF1059 Yin Qiao Jie Du Capsule 银翘解毒胶囊
TCMF1060 Yin Qiao Jie Du Granules 银翘解毒颗粒
TCMF1058 Yin Qiao Jie Du Ruan Capsule 银翘解毒软胶囊
TCMF1057 Yin Qiao Jie Du Tablet 银翘解毒片
TCMF6577 Yuan Ji Lin Gan He Tea 源吉林甘和茶
TCMF6411 Zhi Qin Qing Re Oral Liquid 栀芩清热液
TCMF798 Zhi Qin Qing Re Recipe 栀芩清热合剂

Targeted Human Proteins by the Ingredient of Component

Target ID Gene Symbol Target Name Target Class Uniprot ID
TCMT1 EHMT2 Histone-lysine N-methyltransferase, H3 lysine-9 specific 3 Transferase Q96KQ7
TCMT100 TTR Transthyretin Unclassified P02766
TCMT101 PTPN1 Protein-tyrosine phosphatase 1B Hydrolase P18031
TCMT11 HIF1A Hypoxia-inducible factor 1 alpha Transcription factor Q16665
TCMT13 APEX1 DNA-(apurinic or apyrimidinic site) lyase Lyase P27695
TCMT130 ALOX5 Arachidonate 5-lipoxygenase Oxidoreductase P09917
TCMT131 ACHE Acetylcholinesterase Hydrolase P22303
TCMT133 CA1 Carbonic anhydrase I Lyase P00915
TCMT134 CA2 Carbonic anhydrase II Lyase P00918
TCMT135 CA14 Carbonic anhydrase XIV Lyase Q9ULX7
TCMT136 CA12 Carbonic anhydrase XII Lyase O43570
TCMT137 CA9 Carbonic anhydrase IX Lyase Q16790
TCMT138 CA7 Carbonic anhydrase VII Lyase P43166
TCMT139 CA6 Carbonic anhydrase VI Lyase P23280
TCMT140 CA5B Carbonic anhydrase VB Lyase Q9Y2D0
TCMT141 CA5A Carbonic anhydrase VA Lyase P35218
TCMT142 CA4 Carbonic anhydrase IV Lyase P22748
TCMT143 CA3 Carbonic anhydrase III Lyase P07451
TCMT159 TYR Tyrosinase Oxidoreductase P14679
TCMT161 HCAR2 Hydroxycarboxylic acid receptor 2 GPCR Q8TDS4
TCMT166 AKR1C2 Aldo-keto reductase family 1 member C2 Oxidoreductase P52895
TCMT167 AKR1C3 Aldo-keto-reductase family 1 member C3 Oxidoreductase P42330
TCMT168 AKR1C4 Aldo-keto reductase family 1 member C4 Oxidoreductase P17516
TCMT17 POLB DNA polymerase beta Transferase P06746
TCMT18 GAA Lysosomal alpha-glucosidase Hydrolase P10253
TCMT189 DUSP3 Dual specificity protein phosphatase 3 Hydrolase P51452
TCMT2 MAPT Microtubule-associated protein tau Unclassified P10636
TCMT223 AKR1B1 Aldose reductase Oxidoreductase P15121
TCMT280 AKR1B10 Aldo-keto reductase family 1 member B10 Oxidoreductase O60218
TCMT295 MMP1 Matrix metalloproteinase-1 Hydrolase P03956
TCMT306 MMP2 Matrix metalloproteinase-2 Hydrolase P08253
TCMT321 MMP9 Matrix metalloproteinase 9 Hydrolase P14780
TCMT33 CYP3A4 Cytochrome P450 3A4 Oxidoreductase P08684
TCMT423 EGFR Epidermal growth factor receptor erbB1 Kinase P00533
TCMT45 APP Beta amyloid A4 protein Unclassified P05067
TCMT6 NFKB1 Nuclear factor NF-kappa-B p105 subunit Transcription factor P19838
TCMT69 THRB Thyroid hormone receptor beta-1 Nuclear receptor P10828
TCMT8 KDM4E Lysine-specific demethylase 4D-like Oxidoreductase B2RXH2
TCMT80 MAPK1 MAP kinase ERK2 Kinase P28482
TCMT82 ESR1 Estrogen receptor alpha Nuclear receptor P03372
TCMT87 CYP2C9 Cytochrome P450 2C9 Oxidoreductase P11712
TCMT95 MPG DNA-3-methyladenine glycosylase Hydrolase P29372


Targeted Pathogenic Microbes by the Ingredient of Component

Target ID Target Name
TCMT1099 Neuraminidase
TCMT1108 Integrase
TCMT1218 Staphylococcus aureus
TCMT1226 Klebsiella pneumoniae
TCMT1229 Enterococcus faecalis
TCMT1246 Escherichia coli
TCMT1251 Candida albicans
TCMT1346 Helicobacter pylori
TCMT1458 Filobasidiella neoformans

Ingredient Structrues

Ingredient ID: TCMC897
Formula: C16H18O9

Ingredient ID: TCMC847
Formula: C9H8O4

Ingredient ID: TCMC5907
Formula: C31H52O

Ingredient ID: TCMC3703
Formula: C31H52O

Ingredient ID: TCMC2233
Formula: C21H20O10

Ingredient ID: TCMC182
Formula: C9H8O4

Ingredient ID: TCMC1418
Formula: C21H20O10

Ingredient ID: TCMC1403
Formula: C21H20O11

Properties

Ingredient ID Formulae Name MW AlogP MlogP XlogP # HBA # HBD PSA # Rotatable Bond # Ring # Heacy Atom Lipinski RO5 Violation
TCMC182 C9H8O4 (Z)-3-(3,4-Dihydroxyphenyl)Prop-2-Enoic Acid 180.04 -0.7993 2.01 1.141 2 3 77.76 5 1 13 0
TCMC847 C9H8O4 Caffeic Acid 180.04 -0.7993 2.01 1.141 2 3 77.76 5 1 13 0
TCMC897 C16H18O9 Chlorogenic Acid 354.1 -2.1962 2.23 -0.447 7 6 164.75 11 2 25 1
TCMC1403 C21H20O11 Isoorientin 448.1 -4.5805 2.56 -1.042 6 8 197.37 11 4 32 1
TCMC1418 C21H20O10 Isovitexin 432.11 -4.1202 2.67 -0.508 6 7 177.14 10 4 31 1
TCMC2233 C21H20O10 Vitexin 432.11 -4.1202 2.67 -0.508 6 7 177.14 10 4 31 1
TCMC3703 C31H52O Cylindrin 440.4018163 3.5617 4.76 11.967 1 0 9.23 2 5 32 1
TCMC5907 C31H52O Arundoin 440.4018163 3.5617 4.76 11.967 1 0 9.23 2 5 32 1

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1. General Information of the Component  
2. TCM Prescriptions with the Component  
3. Putative Targets  
4. Activity & References for Filtering Putative Targets  
5. Ingredient Data & Chemical Structure Information (Properties, InChI, InChIkey, SMILES, etc.)