Component: Loropetalum chinense 继木叶浸膏


Description of the Component

Component ID
 TCMH1025
Latin Name
 Loropetalum chinense
English Name
 NA
Chinese Pinyin Name
 Ji Mu Ye Jin Gao
中文名
 继木叶浸膏
TCM Properties
TCM Meridians
Therapeutic Class English
Therapeutic Class Chinese
Functions
Toxicity
 NA
Geo-authentic habitats (道地产区)
 NA
Reference
 CFDA
Barcode ID
 GBVG2178-11, GBVG2183-11
Barcode Source
 BOLDSYSTEMS

TCM Prescriptions with the Component

Prescription ID Prescription English Name Prescription Chinese Name
TCMFx6487 Xue Jian Ning 血见宁

Targeted Human Proteins by the Ingredient of Component

Target ID Gene Symbol Target Name Target Class Uniprot ID
TCMT1 EHMT2 Histone-lysine N-methyltransferase, H3 lysine-9 specific 3 Transferase Q96KQ7
TCMT133 CA1 Carbonic anhydrase I Lyase P00915
TCMT134 CA2 Carbonic anhydrase II Lyase P00918
TCMT135 CA14 Carbonic anhydrase XIV Lyase Q9ULX7
TCMT136 CA12 Carbonic anhydrase XII Lyase O43570
TCMT137 CA9 Carbonic anhydrase IX Lyase Q16790
TCMT138 CA7 Carbonic anhydrase VII Lyase P43166
TCMT139 CA6 Carbonic anhydrase VI Lyase P23280
TCMT140 CA5B Carbonic anhydrase VB Lyase Q9Y2D0
TCMT141 CA5A Carbonic anhydrase VA Lyase P35218
TCMT142 CA4 Carbonic anhydrase IV Lyase P22748
TCMT143 CA3 Carbonic anhydrase III Lyase P07451
TCMT156 CYP19A1 Cytochrome P450 19A1 Oxidoreductase P11511
TCMT162 UGT1A1 UDP-glucuronosyltransferase 1-1 Transferase P22309
TCMT2 MAPT Microtubule-associated protein tau Unclassified P10636
TCMT223 AKR1B1 Aldose reductase Oxidoreductase P15121
TCMT248 CXCL8 Interleukin-8 Unclassified P10145
TCMT280 AKR1B10 Aldo-keto reductase family 1 member B10 Oxidoreductase O60218
TCMT31 CYP2C19 Cytochrome P450 2C19 Oxidoreductase P33261
TCMT33 CYP3A4 Cytochrome P450 3A4 Oxidoreductase P08684
TCMT34 CYP2D6 Cytochrome P450 2D6 Oxidoreductase P10635
TCMT41 IDH1 Isocitrate dehydrogenase [NADP] cytoplasmic Oxidoreductase O75874
TCMT45 APP Beta amyloid A4 protein Unclassified P05067
TCMT67 PPARG Peroxisome proliferator-activated receptor gamma Nuclear receptor P37231
TCMT8 KDM4E Lysine-specific demethylase 4D-like Oxidoreductase B2RXH2
TCMT80 MAPK1 MAP kinase ERK2 Kinase P28482
TCMT82 ESR1 Estrogen receptor alpha Nuclear receptor P03372
TCMT822 FUT7 Alpha-(1,3)-fucosyltransferase 7 Transferase Q11130


Targeted Pathogenic Microbes by the Ingredient of Component

Target ID Target Name
TCMT1178 Actinomyces viscosus
TCMT1218 Staphylococcus aureus
TCMT1346 Helicobacter pylori
TCMT1438 Plasmodium falciparum
TCMT1454 Bacillus subtilis

Ingredient Structrues

Ingredient ID: TCMC897
Formula: C16H18O9

Ingredient ID: TCMC603
Formula: C20H30O2

Ingredient ID: TCMC2553
Formula: C20H30O

Ingredient ID: TCMC2118
Formula: C17H14O8

Ingredient ID: TCMC1288
Formula: C11H14N2

Ingredient ID: TCMC1202
Formula: C7H6O5

Properties

Ingredient ID Formulae Name MW AlogP MlogP XlogP # HBA # HBD PSA # Rotatable Bond # Ring # Heacy Atom Lipinski RO5 Violation
TCMC603 C20H30O2 Abietic Acid 302.22 1.3773 3.44 6.113 2 1 37.3 7 3 22 1
TCMC897 C16H18O9 Chlorogenic Acid 354.1 -2.1962 2.23 -0.447 7 6 164.75 11 2 25 1
TCMC1202 C7H6O5 Gallic Acid 170.02 -1.6207 1.68 0.002 2 4 97.99 5 1 12 0
TCMC1288 C11H14N2 Gramine 174.12 -0.191 2.45 1.992 2 1 19.03 4 2 13 0
TCMC2118 C17H14O8 Syringetin 346.07 -2.4445 2.45 1.027 2 4 125.68 9 3 25 0
TCMC2553 C20H30O Pomiferin A 286.23 0.6925 3.55 8.253 1 1 20.23 7 3 21 1

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1. General Information of the Component  
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3. Putative Targets  
4. Activity & References for Filtering Putative Targets  
5. Ingredient Data & Chemical Structure Information (Properties, InChI, InChIkey, SMILES, etc.)