Component: Eupatorium rebaudianum 甜叶菊

Description of the Component

Component ID
Latin Name
Eupatorium rebaudianum
English Name
Rebaud eupatorium*
Chinese Pinyin Name
Tian Ye Ju
TCM Properties
TCM Meridians
Therapeutic Class English
Therapeutic Class Chinese
Geo-authentic habitats (道地产区)
Chinese Pharmacopoeia (2015)
Barcode ID
Barcode Source

TCM Prescriptions with the Component

Prescription ID Prescription English Name Prescription Chinese Name
TCMFx4951 Jian Er Le Infusion 健儿乐冲剂
TCMFx904 Jian Er Le Granules 健儿乐颗粒
TCMF4088 Jian Min Yan Hou Tablets 健民咽喉片
TCMFx4682 Long Yan Bu Shen Wine 龙燕补肾酒
TCMFx5610 Qing Re Ming Mu Tea 清热明目茶
TCMF5500 Wei Tian Mei Jiang Tang Tea 维甜美降糖茶
TCMFx6166 Xiao Ke Jiang Tang Tablets 消渴降糖片
TCMFx6715 Yan You Tea 艳友茶
TCMF6779 Zeng Kang Ning Tablets 增抗宁片

Targeted Human Proteins by the Ingredient of Component

Target ID Gene Symbol Target Name Target Class Uniprot ID
TCMT1 EHMT2 Histone-lysine N-methyltransferase, H3 lysine-9 specific 3 Transferase Q96KQ7
TCMT11 HIF1A Hypoxia-inducible factor 1 alpha Transcription factor Q16665
TCMT113 OPRD1 Delta opioid receptor GPCR P41143
TCMT116 OPRM1 Mu opioid receptor GPCR P35372
TCMT117 OPRK1 Kappa opioid receptor GPCR P41145
TCMT160 HTR7 Serotonin 7 (5-HT7) receptor GPCR P34969
TCMT162 UGT1A1 UDP-glucuronosyltransferase 1-1 Transferase P22309
TCMT2 MAPT Microtubule-associated protein tau Unclassified P10636
TCMT223 AKR1B1 Aldose reductase Oxidoreductase P15121
TCMT241 CHRNA7 Neuronal acetylcholine receptor protein alpha-7 subunit Ion channel P36544
TCMT242 HRH3 Histamine H3 receptor GPCR Q9Y5N1
TCMT243 ADRA2C Alpha-2c adrenergic receptor GPCR P18825
TCMT244 HRH1 Histamine H1 receptor GPCR P35367
TCMT246 HRH4 Histamine H4 receptor GPCR Q9H3N8
TCMT27 DRD1 Dopamine D1 receptor GPCR P21728
TCMT280 AKR1B10 Aldo-keto reductase family 1 member B10 Oxidoreductase O60218
TCMT290 CHRM5 Muscarinic acetylcholine receptor M5 GPCR P08912
TCMT291 CHRM3 Muscarinic acetylcholine receptor M3 GPCR P20309
TCMT292 CHRM1 Muscarinic acetylcholine receptor M1 GPCR P11229
TCMT293 CHRM2 Muscarinic acetylcholine receptor M2 GPCR P08172
TCMT3 ALOX15 Arachidonate 15-lipoxygenase Oxidoreductase P16050
TCMT31 CYP2C19 Cytochrome P450 2C19 Oxidoreductase P33261
TCMT313 HTR2B Serotonin 2b (5-HT2b) receptor GPCR P41595
TCMT314 HTR2C Serotonin 2c (5-HT2c) receptor GPCR P28335
TCMT315 HTR6 Serotonin 6 (5-HT6) receptor GPCR P50406
TCMT33 CYP3A4 Cytochrome P450 3A4 Oxidoreductase P08684
TCMT34 CYP2D6 Cytochrome P450 2D6 Oxidoreductase P10635
TCMT36 HTR1A Serotonin 1a (5-HT1a) receptor GPCR P08908
TCMT38 DRD2 Dopamine D2 receptor GPCR P14416
TCMT45 APP Beta amyloid A4 protein Unclassified P05067
TCMT551 CHRM4 Muscarinic acetylcholine receptor M4 GPCR P08173
TCMT559 ADRB2 Beta-2 adrenergic receptor GPCR P07550
TCMT633 SLC6A4 Serotonin transporter Transporter P31645
TCMT634 SLC6A2 Norepinephrine transporter Transporter P23975
TCMT635 SLC6A3 Dopamine transporter Transporter Q01959
TCMT642 ADRA1D Alpha-1d adrenergic receptor GPCR P25100
TCMT643 ADRA1A Alpha-1a adrenergic receptor GPCR P35348
TCMT644 HTR3A Serotonin 3a (5-HT3a) receptor Ion channel P46098
TCMT645 HTR1E Serotonin 1e (5-HT1e) receptor GPCR P28566
TCMT646 HTR5A Serotonin 5a (5-HT5a) receptor GPCR P47898
TCMT647 ADRA2B Alpha-2b adrenergic receptor GPCR P18089
TCMT648 DRD4 Dopamine D4 receptor GPCR P21917
TCMT649 DRD5 Dopamine D5 receptor GPCR P21918
TCMT650 ADRA1B Alpha-1b adrenergic receptor GPCR P35368
TCMT651 DRD3 Dopamine D3 receptor GPCR P35462
TCMT8 KDM4E Lysine-specific demethylase 4D-like Oxidoreductase B2RXH2
TCMT82 ESR1 Estrogen receptor alpha Nuclear receptor P03372
TCMT87 CYP2C9 Cytochrome P450 2C9 Oxidoreductase P11712

Targeted Pathogenic Microbes by the Ingredient of Component

Target ID Target Name
TCMT1090 Human immunodeficiency virus type 1 integrase
TCMT1108 Integrase
TCMT1246 Escherichia coli
TCMT1253 Penicillium chrysogenum
TCMT1346 Helicobacter pylori
TCMT1438 Plasmodium falciparum
TCMT1454 Bacillus subtilis
TCMT1462 Streptococcus mutans
TCMT1465 Entamoeba histolytica

Ingredient Structrues

Ingredient ID: TCMC897
Formula: C16H18O9

Ingredient ID: TCMC821
Formula: C19H21NO4

Ingredient ID: TCMC469
Formula: C25H24O12

Ingredient ID: TCMC2697
Formula: C10H16O3

Ingredient ID: TCMC2576
Formula: C18H19NO4

Ingredient ID: TCMC2541
Formula: C10H18O

Ingredient ID: TCMC2506
Formula: C19H21NO4

Ingredient ID: TCMC2324
Formula: C10H16

Ingredient ID: TCMC2317
Formula: C19H21NO4

Ingredient ID: TCMC2222
Formula: C8H8O4

Ingredient ID: TCMC1748
Formula: C20H23NO4

Ingredient ID: TCMC1493
Formula: C10H18O

Ingredient ID: TCMC1387
Formula: C20H23NO4

Ingredient ID: TCMC1383
Formula: C19H21NO4


Ingredient ID Formulae Name MW AlogP MlogP XlogP # HBA # HBD PSA # Rotatable Bond # Ring # Heacy Atom Lipinski RO5 Violation
TCMC469 C25H24O12 4,5-Dicaffeoylquinic Acid 516.13 -2.3865 2.89 1.085 8 7 211.28 16 3 37 1
TCMC821 C19H21NO4 Boldine 327.15 -0.6295 3 1.199 1 2 62.16 7 4 24 0
TCMC897 C16H18O9 Chlorogenic Acid 354.1 -2.1962 2.23 -0.447 7 6 164.75 11 2 25 1
TCMC1383 C19H21NO4 Isoboldine 327.15 -0.6295 3 1.199 1 2 62.16 7 4 24 0
TCMC1387 C20H23NO4 Isocorydine 341.16 -0.221 3.11 1.718 1 1 51.16 8 4 25 0
TCMC1493 C10H18O Linalool (+) 154.14 2.4692 2.45 2.468 1 1 20.23 8 0 11 0
TCMC1748 C20H23NO4 N-Methyllaurotetanine 341.16 -0.221 3.11 1.718 1 1 51.16 8 4 25 0
TCMC2222 C8H8O4 Vanillic Acid 168.04 -0.7519 1.9 0.626 2 2 66.76 5 1 12 0
TCMC2317 C19H21NO4 Laurotetanine 327.15 -0.7569 3 1.479 1 2 59.95 7 4 24 0
TCMC2324 C10H16 Limonene 136.13 2.1424 2.56 3.729 0 0 0 3 1 10 0
TCMC2506 C19H21NO4 (+)-Norisocorydine 327.15 -0.7569 3 1.479 1 2 59.95 7 4 24 0
TCMC2541 C10H18O Alpha-Terpineol 154.14 1.1223 2.45 2.369 1 1 20.23 5 1 11 0
TCMC2576 C18H19NO4 Norboldine 313.13 -1.1654 2.89 0.96 1 3 70.95 6 4 23 0
TCMC2697 C10H16O3 (6R)-3,7-Dimethyl-7-Hydroxy-2-Octen-6-Olide 184.11 0.5742 2.23 1.091 3 1 46.53 5 1 13 0

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