Component: Alpinia katsumadai 草豆蔻


Description of the Component

Component ID
TCMH214
Latin Name
Alpinia katsumadai
English Name
Katsumada galangal
Chinese Pinyin Name
Cao Dou Kou
中文名
草豆蔻
TCM Properties
Warm,Pungent
TCM Meridians
Spleen,Stomach
Therapeutic Class English
For desolving dampness by flavors
Therapeutic Class Chinese
芳香化湿
Functions
remove damp, invigorate the spleen function, warm the stomach and arrest vomiting
Toxicity
NA
Geo-authentic habitats (道地产区)
Hainan Province
Reference
Chinese Pharmacopoeia (2015)
Barcode ID
KY454001
Barcode Source
GenBank

TCM Prescriptions with the Component

Prescription ID Prescription English Name Prescription Chinese Name
TCMF2973 Ba Bao Rui Sheng Pills 八宝瑞生丸
TCMF2970 Ba Xian You 八仙油
TCMF3028 Bai Kou Tiao Zhong Pills 白蔻调中丸
TCMFx3853 Cao Dou Kou Ding 草豆蔻酊
TCMF2036 Decoction of Magnoliae Officinalis for Warming Middle Jiao 厚朴温中汤
TCMFx3418 Die Da Wan Hua You 跌打万花油
TCMF3465 Ding Chen Tou Ge Pills 丁沉透膈丸
TCMFx3644 Fo Shan Ren Shen Zai Zao Pills 佛山人参再造丸
TCMFx3635 Fo Shan Ren Shen Zai Zao Tablets 佛山人参再造片
TCMFx3276 Fu Fang Cao Dou Kou Ding 复方草豆蔻酊
TCMFx3367 Fu Fang Da Huang Ding 复方大黄酊
TCMFx3709 Fu Fang Long Dan Ding 复方龙胆酊
TCMF3888 Guang Dong Shen Qu 广东神曲
TCMF4658 Hou Pu Wen Zhong Pills 厚朴温中丸
TCMFx4650 Hou Zao Niu Huang Powder 猴枣牛黄散
TCMFx4264 Hui Sheng Zai Zao Pills 回生再造丸
TCMFx4274 Hui Tian Zai Zao Pills 回天再造丸
TCMFx4325 Huo Luo Pills 活络丸
TCMFx4657 Ji Kun Pills 济坤丸
TCMFx4217 Jian Pi Xiao Shi Pills 健脾消食丸
TCMF907 Jian Wei Tablet 健胃片
TCMFx4395 Jian Wei Zhi Tong Tablets 健胃止痛片
TCMF6925 Jie Bai Capsules 洁白胶囊
TCMF1410 Jiebai Pills 洁白丸
TCMF2556 Jiebai Pills 洁白丸
TCMFx4215 Kang Shuan Zai Zao Pills 抗栓再造丸
TCMFx578 Kang Shuan Zai Zao Pills 抗栓再造丸
TCMF4472 Min Dong Jian Qu 闽东建曲
TCMFx5562 Ren Dan 人丹
TCMFx5459 Ren Shen Jian Pi Pills 人参健脾丸
TCMFx5452 Ren Shen Jian Pi Tablets 人参健脾片
TCMFx5537 Ren Shen Zai Zao Pills 人参再造丸
TCMF5201 San Feng Huo Luo Pills 散风活络丸
TCMFx5694 Shang Ke Wan Hua You 伤科万花油
TCMFx3228 Shen Gui Zai Zao Pills 参桂再造丸
TCMFx5605 Shu Feng Zai Zao Pills 疏风再造丸
TCMF5285 Shu Gan Jian Wei Infusion 舒肝健胃冲剂
TCMFx5825 Tong Luo Huo Xue Pills 通络活血丸
TCMF5609 Wei De An Capsules 胃得安胶囊
TCMF5616 Wei De An Tablets 胃得安片
TCMFx6287 Xiao Shi Jian Pi Pills 消食健脾丸
TCMF6820 Yang Wei Ning Capsules 养胃宁胶囊
TCMF6478 Yu Zhi Ping An Pills 御制平安丸
TCMFx470 Zai Zao Pills 再造丸
TCMFx6224 Zhong Feng Zai Zao Pills 中风再造丸
TCMF6819 Zi Kou Pills 紫蔻丸

Targeted Human Proteins by the Ingredient of Component

Target ID Gene Symbol Target Name Target Class Uniprot ID
TCMT1 EHMT2 Histone-lysine N-methyltransferase, H3 lysine-9 specific 3 Transferase Q96KQ7
TCMT11 HIF1A Hypoxia-inducible factor 1 alpha Transcription factor Q16665
TCMT112 ADORA3 Adenosine A3 receptor GPCR P0DMS8
TCMT125 GBA Beta-glucocerebrosidase Hydrolase P04062
TCMT13 APEX1 DNA-(apurinic or apyrimidinic site) lyase Lyase P27695
TCMT130 ALOX5 Arachidonate 5-lipoxygenase Oxidoreductase P09917
TCMT131 ACHE Acetylcholinesterase Hydrolase P22303
TCMT132 BCHE Butyrylcholinesterase Hydrolase P06276
TCMT133 CA1 Carbonic anhydrase I Lyase P00915
TCMT134 CA2 Carbonic anhydrase II Lyase P00918
TCMT135 CA14 Carbonic anhydrase XIV Lyase Q9ULX7
TCMT136 CA12 Carbonic anhydrase XII Lyase O43570
TCMT137 CA9 Carbonic anhydrase IX Lyase Q16790
TCMT138 CA7 Carbonic anhydrase VII Lyase P43166
TCMT139 CA6 Carbonic anhydrase VI Lyase P23280
TCMT140 CA5B Carbonic anhydrase VB Lyase Q9Y2D0
TCMT141 CA5A Carbonic anhydrase VA Lyase P35218
TCMT142 CA4 Carbonic anhydrase IV Lyase P22748
TCMT143 CA3 Carbonic anhydrase III Lyase P07451
TCMT150 RORC Nuclear receptor ROR-gamma Nuclear receptor P51449
TCMT151 PRKCA Protein kinase C alpha Kinase P17252
TCMT152 PRKCB Protein kinase C beta Kinase P05771
TCMT153 PRKCG Protein kinase C gamma Kinase P05129
TCMT154 PRKCD Protein kinase C delta Kinase Q05655
TCMT155 PRKCE Protein kinase C epsilon Kinase Q02156
TCMT156 CYP19A1 Cytochrome P450 19A1 Oxidoreductase P11511
TCMT158 EPHX2 Epoxide hydratase Lyase P34913
TCMT162 UGT1A1 UDP-glucuronosyltransferase 1-1 Transferase P22309
TCMT17 POLB DNA polymerase beta Transferase P06746
TCMT18 GAA Lysosomal alpha-glucosidase Hydrolase P10253
TCMT186 MAOB Monoamine oxidase B Oxidoreductase P27338
TCMT187 AR Androgen Receptor Nuclear receptor P10275
TCMT188 DHFR Dihydrofolate reductase Oxidoreductase P00374
TCMT2 MAPT Microtubule-associated protein tau Unclassified P10636
TCMT206 CYP2A6 Cytochrome P450 2A6 Oxidoreductase P11509
TCMT215 CYP1A1 Cytochrome P450 1A1 Oxidoreductase P04798
TCMT218 CYP2B6 Cytochrome P450 2B6 Oxidoreductase P20813
TCMT219 CYP1A2 Cytochrome P450 1A2 Oxidoreductase P05177
TCMT223 AKR1B1 Aldose reductase Oxidoreductase P15121
TCMT225 CA13 Carbonic anhydrase XIII Lyase Q8N1Q1
TCMT236 ESR2 Estrogen receptor beta Nuclear receptor Q92731
TCMT239 PIM1 Serine/threonine-protein kinase PIM1 Kinase P11309
TCMT240 AMY1A Salivary alpha-amylase Unclassified P04745
TCMT248 CXCL8 Interleukin-8 Unclassified P10145
TCMT249 CDK6 Cyclin-dependent kinase 6 Kinase Q00534
TCMT254 CBR1 Carbonyl reductase [NADPH] 1 Oxidoreductase P16152
TCMT257 CYP1B1 Cytochrome P450 1B1 Oxidoreductase Q16678
TCMT260 FLT3 Tyrosine-protein kinase receptor FLT3 Kinase P36888
TCMT261 DAPK1 Death-associated protein kinase 1 Kinase P53355
TCMT265 GSK3B Glycogen synthase kinase-3 beta Kinase P49841
TCMT276 SLCO2B1 Solute carrier organic anion transporter family member 2B1 Transporter O94956
TCMT277 SLCO1B3 Solute carrier organic anion transporter family member 1B3 Transporter Q9NPD5
TCMT278 SLCO1B1 Solute carrier organic anion transporter family member 1B1 Transporter Q9Y6L6
TCMT281 DPP4 Dipeptidyl peptidase IV Unclassified P27487
TCMT3 ALOX15 Arachidonate 15-lipoxygenase Oxidoreductase P16050
TCMT30 PTGS2 Cyclooxygenase-2 Oxidoreductase P35354
TCMT303 KCNA3 Voltage-gated potassium channel subunit Kv1.3 Ion channel P22001
TCMT31 CYP2C19 Cytochrome P450 2C19 Oxidoreductase P33261
TCMT33 CYP3A4 Cytochrome P450 3A4 Oxidoreductase P08684
TCMT34 CYP2D6 Cytochrome P450 2D6 Oxidoreductase P10635
TCMT39 PDE5A Phosphodiesterase 5A Hydrolase O76074
TCMT41 IDH1 Isocitrate dehydrogenase [NADP] cytoplasmic Oxidoreductase O75874
TCMT44 GLO1 Glyoxalase I Lyase Q04760
TCMT45 APP Beta amyloid A4 protein Unclassified P05067
TCMT47 BCL2 Apoptosis regulator Bcl-2 Ion channel P10415
TCMT59 BCL2L1 Apoptosis regulator Bcl-X Ion channel Q07817
TCMT6 NFKB1 Nuclear factor NF-kappa-B p105 subunit Transcription factor P19838
TCMT601 F2 Thrombin Unclassified P00734
TCMT61 MCL1 Induced myeloid leukemia cell differentiation protein Mcl-1 Unclassified Q07820
TCMT629 ABCC1 Multidrug resistance-associated protein 1 Transporter P33527
TCMT63 PPARA Peroxisome proliferator-activated receptor alpha Nuclear receptor Q07869
TCMT64 PPARD Peroxisome proliferator-activated receptor delta Nuclear receptor Q03181
TCMT65 HSD17B1 Estradiol 17-beta-dehydrogenase 1 Oxidoreductase P14061
TCMT66 HSD17B2 Estradiol 17-beta-dehydrogenase 2 Oxidoreductase P37059
TCMT67 PPARG Peroxisome proliferator-activated receptor gamma Nuclear receptor P37231
TCMT707 ADORA2A Adenosine A2a receptor GPCR P29274
TCMT747 ABCG2 ATP-binding cassette sub-family G member 2 Transporter Q9UNQ0
TCMT8 KDM4E Lysine-specific demethylase 4D-like Oxidoreductase B2RXH2
TCMT80 MAPK1 MAP kinase ERK2 Kinase P28482
TCMT81 ALOX12 Arachidonate 12-lipoxygenase Oxidoreductase P18054
TCMT82 ESR1 Estrogen receptor alpha Nuclear receptor P03372
TCMT83 CD38 Lymphocyte differentiation antigen CD38 Unclassified P28907
TCMT87 CYP2C9 Cytochrome P450 2C9 Oxidoreductase P11712
TCMT99 SHBG Testis-specific androgen-binding protein Unclassified P04278


Targeted Pathogenic Microbes by the Ingredient of Component

Target ID Target Name
TCMT1090 Human immunodeficiency virus type 1 integrase
TCMT1094 3-oxoacyl-acyl-carrier protein reductase
TCMT1099 Neuraminidase
TCMT1107 Protease
TCMT1136 Neuraminidase
TCMT1181 Mycobacterium tuberculosis H37Ra
TCMT1189 Pseudomonas fluorescens
TCMT1212 Verticillium dahliae
TCMT1218 Staphylococcus aureus
TCMT1222 Plasmodium falciparum D6
TCMT1229 Enterococcus faecalis
TCMT1251 Candida albicans
TCMT1253 Penicillium chrysogenum
TCMT1438 Plasmodium falciparum
TCMT1448 Enterobacter aerogenes
TCMT1454 Bacillus subtilis
TCMT1455 Mycobacterium tuberculosis H37Rv
TCMT1458 Filobasidiella neoformans
TCMT1462 Streptococcus mutans
TCMT1463 Mycobacterium tuberculosis
TCMT1465 Entamoeba histolytica

Ingredient Structrues

Ingredient ID: TCMC913
Formula: C15H14O6

Ingredient ID: TCMC908
Formula: C15H10O4

Ingredient ID: TCMC889
Formula: C15H12O

Ingredient ID: TCMC878
Formula: C15H14O6

Ingredient ID: TCMC870
Formula: C16H14O4

Ingredient ID: TCMC816
Formula: C14H18O6

Ingredient ID: TCMC801
Formula: C29H50O

Ingredient ID: TCMC761
Formula: C7H6O

Ingredient ID: TCMC525
Formula: C15H12O5

Ingredient ID: TCMC4548
Formula: C12H20O2

Ingredient ID: TCMC4174
Formula: C15H26O

Ingredient ID: TCMC4153
Formula: C16H14O4

Ingredient ID: TCMC4102
Formula: C10H10O2

Ingredient ID: TCMC3203
Formula: C10H18O

Ingredient ID: TCMC3099
Formula: C10H16

Ingredient ID: TCMC3
Formula: C15H14O6

Ingredient ID: TCMC2901
Formula: C10H16

Ingredient ID: TCMC2896
Formula: C12H20O2

Ingredient ID: TCMC2822
Formula: C15H24

Ingredient ID: TCMC254
Formula: C12H12

Ingredient ID: TCMC2539
Formula: C10H16

Ingredient ID: TCMC2484
Formula: C10H18O

Ingredient ID: TCMC2450
Formula: C16H14O4

Ingredient ID: TCMC2308
Formula: C19H18O2

Ingredient ID: TCMC2307
Formula: C32H28O4

Ingredient ID: TCMC2266
Formula: C19H22O

Ingredient ID: TCMC2256
Formula: C19H18O

Ingredient ID: TCMC2031
Formula: C27H30O16

Ingredient ID: TCMC1898
Formula: C15H12O4

Ingredient ID: TCMC1881
Formula: C36H56O8

Ingredient ID: TCMC1734
Formula: C15H12O5

Ingredient ID: TCMC1727
Formula: C28H44O3

Ingredient ID: TCMC166
Formula: C15H12O4

Ingredient ID: TCMC1608
Formula: C10H16

Ingredient ID: TCMC1493
Formula: C10H18O

Ingredient ID: TCMC1397
Formula: C16H12O6

Ingredient ID: TCMC1201
Formula: C15H10O5

Ingredient ID: TCMC1172
Formula: C15H26O

Ingredient ID: TCMC1081
Formula: C12H24O2

Properties

Ingredient ID Formulae Name MW AlogP MlogP XlogP # HBA # HBD PSA # Rotatable Bond # Ring # Heacy Atom Lipinski RO5 Violation
TCMC3 C15H14O6 (-)-Catechin 290.08 -2.494 2.45 0.406 1 5 110.38 6 3 21 0
TCMC166 C15H12O4 (R)-Pinocembrin 256.07 -1.3541 2.67 2.493 1 2 66.76 3 3 19 0
TCMC254 C12H12 1,7-Dimethylnaphthalene 156.09 1.284 2.78 6.584 0 0 0 2 2 12 1
TCMC525 C15H12O5 5,7-Dihydroxy-2-(4-Hydroxyphenyl)-2,3-Dihydrochromen-4-One 272.07 -1.8144 2.56 0.897 1 3 86.99 4 3 20 0
TCMC761 C7H6O Benzaldehyde 106.04 -0.1924 2.12 3.08 1 0 17.07 1 1 8 0
TCMC801 C29H50O Beta-Sitosterol 414.39 1.3 4.54 11.595 1 1 20.23 13 4 30 1
TCMC816 C14H18O6 Bis(2-Methoxyethyl) Benzene-1,2-Dicarboxylate 282.11 -0.2394 2.34 1.954 6 0 71.06 12 1 20 0
TCMC870 C16H14O4 Cardamomin 270.09 -0.8751 2.78 4.338 1 2 66.76 7 2 20 0
TCMC878 C15H14O6 Catechin 290.08 -2.494 2.45 0.406 1 5 110.38 6 3 21 0
TCMC889 C15H12O Chalcone 208.09 0.0973 3 6.912 1 0 17.07 3 2 16 1
TCMC908 C15H10O4 Chrysin 254.06 -1.4242 2.67 3.163 1 2 66.76 3 3 19 0
TCMC913 C15H14O6 Cianidanol 290.08 -2.494 2.45 0.406 1 5 110.38 6 3 21 0
TCMC1081 C12H24O2 Dodecanoate 200.18 -2.7457 2.56 5.294 2 1 37.3 12 0 14 1
TCMC1172 C15H26O Farnesol 222.2 3.5719 3 4.346 1 1 20.23 12 0 16 0
TCMC1201 C15H10O5 Galangin 270.05 -1.8806 2.56 3.511 2 3 86.99 4 3 20 0
TCMC1397 C16H12O6 Isokaempferide 300.06 -2.2764 2.56 1.807 2 3 96.22 6 3 22 0
TCMC1493 C10H18O Linalool (+) 154.14 2.4692 2.45 2.468 1 1 20.23 8 0 11 0
TCMC1608 C10H16 Myrcene 136.13 3.0936 2.56 4.17 0 0 0 6 0 10 0
TCMC1727 C28H44O3 Nandrolone Decanoate 428.33 -1.6843 4.21 8.199 3 0 43.37 12 4 31 1
TCMC1734 C15H12O5 Naringenin 272.07 -1.8144 2.56 0.897 1 3 86.99 4 3 20 0
TCMC1881 C36H56O8 Phorbol Myristate Acetate 616.4 -3.4367 4.54 6.511 8 3 130.36 26 4 44 2
TCMC1898 C15H12O4 Pinocembrin 256.07 -1.3541 2.67 2.493 1 2 66.76 3 3 19 0
TCMC2031 C27H30O16 Rutin 610.15 -6.139 2.67 -1.188 11 10 265.52 17 5 43 2
TCMC2256 C19H18O (4E,6E)-1,7-Diphenylhepta-4,6-Dien-3-One 262.14 0.6623 3.44 8.589 1 0 17.07 6 2 20 1
TCMC2266 C19H22O (S)-1,7-Diphenylhept-6-En-3-Ol 266.17 -0.3009 3.44 9.04 1 1 20.23 8 2 20 1
TCMC2307 C32H28O4 Katsumadain A 476.2 0.0115 4.54 12.019 4 0 52.6 8 5 36 1
TCMC2308 C19H18O2 (E,E)-5-Hydroxy-1,7-Diphenyl-4,6-Heptadien-3-One 278.13 0.0992 3.33 8.086 2 1 37.3 7 2 21 1
TCMC2450 C16H14O4 Pinostrobin 270.09 -0.9456 2.78 3.012 1 1 55.76 4 3 20 0
TCMC2484 C10H18O Terpineol 154.14 1.1223 2.45 1.947 1 1 20.23 5 1 11 0
TCMC2539 C10H16 Gamma-Terpinene 136.13 2.4017 2.56 3.852 0 0 0 4 1 10 0
TCMC2822 C15H24 Alpha-Humulone 204.19 4.1708 3.11 5.94 0 0 0 4 1 15 1
TCMC2896 C12H20O2 1,7,7-Trimethylbicyclo[2.2.1]Heptan-2-Yl Acetate,Bornyl Acetate 196.1463299 1.3223 2.56 3.474 2 0 26.3 2 2 14 0
TCMC2901 C10H16 2,2-Dimethyl-3-Methylenebicyclo[2.2.1]Heptane,Camphene 136.1252005 1.3875 2.56 4.024 0 0 0 0 2 10 0
TCMC3099 C10H16 6,6-Dimethyl-2-Methylenebicyclo[3.1.1]Heptane,Β-Pinene 136.1252005 1.3695 2.56 4.222 0 0 0 0 1 10 0
TCMC3203 C10H18O 1,7,7-Trimethylbicyclo[2.2.1]Heptan-2-Ol,Borneol 154.1357652 0.9432 2.45 2.734 1 1 20.23 0 2 11 0
TCMC4102 C10H10O2 Methyl Cinnamate 162.0680796 0.3723 2.34 4.225 2 0 26.3 3 1 12 0
TCMC4153 C16H14O4 Alpinetin 270.0892089 -0.9456 2.78 3.012 1 1 55.76 2 3 20 0
TCMC4174 C15H26O (Cis-Trans)Farnesol 222.1983655 3.5719 3 4.346 1 1 20.23 7 0 16 0
TCMC4548 C12H20O2 Ethyl Geranate,Geranyl Acetate 196.1463299 2.9433 2.56 3.364 2 0 26.3 6 0 14 0

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1. General Information of the Component  
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3. Putative Targets  
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