TCM-ID Component

Description of the Component

Component ID	TCMH175
Latin Name	Menispermum dauricum
English Name	Asiatic moonseed
Chinese Pinyin Name	Bian Fu Ge
中文名	è™è è‘›
TCM Properties
TCM Meridians
Therapeutic Class English
Therapeutic Class Chinese
Functions
Toxicity	NA
Geo-authentic habitats (道地产区)	NA
Reference	Chinese Pharmacopoeia (2015)
Barcode ID	ITSAJ4217-14
Barcode Source	BOLDSYSTEMS

TCM Prescriptions with the Component

Prescription ID	Prescription English Name	Prescription Chinese Name
TCMF1309	Qingguo Pills	é’æžœä¸¸
TCMF2004	Qingguo Pills	é’æžœä¸¸
TCMFx6903	Wu Song Zhong Tong Ding	äº”æ¾è‚¿ç—›é…Š

Targeted Human Proteins by the Ingredient of Component

Target ID	Gene Symbol	Target Name	Target Class	Uniprot ID
TCMT1	EHMT2	Histone-lysine N-methyltransferase, H3 lysine-9 specific 3	Transferase	Q96KQ7
TCMT131	ACHE	Acetylcholinesterase	Hydrolase	P22303
TCMT133	CA1	Carbonic anhydrase I	Lyase	P00915
TCMT134	CA2	Carbonic anhydrase II	Lyase	P00918
TCMT136	CA12	Carbonic anhydrase XII	Lyase	O43570
TCMT138	CA7	Carbonic anhydrase VII	Lyase	P43166
TCMT142	CA4	Carbonic anhydrase IV	Lyase	P22748
TCMT156	CYP19A1	Cytochrome P450 19A1	Oxidoreductase	P11511
TCMT162	UGT1A1	UDP-glucuronosyltransferase 1-1	Transferase	P22309
TCMT17	POLB	DNA polymerase beta	Transferase	P06746
TCMT18	GAA	Lysosomal alpha-glucosidase	Hydrolase	P10253
TCMT2	MAPT	Microtubule-associated protein tau	Unclassified	P10636
TCMT207	BACE1	Beta-secretase 1	Protease	P56817
TCMT215	CYP1A1	Cytochrome P450 1A1	Oxidoreductase	P04798
TCMT219	CYP1A2	Cytochrome P450 1A2	Oxidoreductase	P05177
TCMT223	AKR1B1	Aldose reductase	Oxidoreductase	P15121
TCMT236	ESR2	Estrogen receptor beta	Nuclear receptor	Q92731
TCMT240	AMY1A	Salivary alpha-amylase	Unclassified	P04745
TCMT254	CBR1	Carbonyl reductase [NADPH] 1	Oxidoreductase	P16152
TCMT257	CYP1B1	Cytochrome P450 1B1	Oxidoreductase	Q16678
TCMT260	FLT3	Tyrosine-protein kinase receptor FLT3	Kinase	P36888
TCMT265	GSK3B	Glycogen synthase kinase-3 beta	Kinase	P49841
TCMT27	DRD1	Dopamine D1 receptor	GPCR	P21728
TCMT276	SLCO2B1	Solute carrier organic anion transporter family member 2B1	Transporter	O94956
TCMT277	SLCO1B3	Solute carrier organic anion transporter family member 1B3	Transporter	Q9NPD5
TCMT278	SLCO1B1	Solute carrier organic anion transporter family member 1B1	Transporter	Q9Y6L6
TCMT31	CYP2C19	Cytochrome P450 2C19	Oxidoreductase	P33261
TCMT33	CYP3A4	Cytochrome P450 3A4	Oxidoreductase	P08684
TCMT36	HTR1A	Serotonin 1a (5-HT1a) receptor	GPCR	P08908
TCMT37	HTR2A	Serotonin 2a (5-HT2a) receptor	GPCR	P28223
TCMT38	DRD2	Dopamine D2 receptor	GPCR	P14416
TCMT39	PDE5A	Phosphodiesterase 5A	Hydrolase	O76074
TCMT41	IDH1	Isocitrate dehydrogenase [NADP] cytoplasmic	Oxidoreductase	O75874
TCMT44	GLO1	Glyoxalase I	Lyase	Q04760
TCMT45	APP	Beta amyloid A4 protein	Unclassified	P05067
TCMT46	F3	Coagulation factor III	Unclassified	P13726
TCMT510	KIT	Stem cell growth factor receptor	Kinase	P10721
TCMT63	PPARA	Peroxisome proliferator-activated receptor alpha	Nuclear receptor	Q07869
TCMT64	PPARD	Peroxisome proliferator-activated receptor delta	Nuclear receptor	Q03181
TCMT648	DRD4	Dopamine D4 receptor	GPCR	P21917
TCMT649	DRD5	Dopamine D5 receptor	GPCR	P21918
TCMT65	HSD17B1	Estradiol 17-beta-dehydrogenase 1	Oxidoreductase	P14061
TCMT651	DRD3	Dopamine D3 receptor	GPCR	P35462
TCMT66	HSD17B2	Estradiol 17-beta-dehydrogenase 2	Oxidoreductase	P37059
TCMT67	PPARG	Peroxisome proliferator-activated receptor gamma	Nuclear receptor	P37231
TCMT8	KDM4E	Lysine-specific demethylase 4D-like	Oxidoreductase	B2RXH2
TCMT82	ESR1	Estrogen receptor alpha	Nuclear receptor	P03372
TCMT87	CYP2C9	Cytochrome P450 2C9	Oxidoreductase	P11712
TCMT99	SHBG	Testis-specific androgen-binding protein	Unclassified	P04278

Targeted Pathogenic Microbes by the Ingredient of Component

Target ID	Target Name
TCMT1090	Human immunodeficiency virus type 1 integrase
TCMT1229	Enterococcus faecalis
TCMT1465	Entamoeba histolytica

Ingredient Structrues

Ingredient ID: TCMC571
Formula: C12H15NO3

Common Name	6,7-Dimethoxy-2-Methyl-3,4-Dihydroisoquinolin-1-One
IUPAC Name	6,7-dimethoxy-2-methyl-3,4-dihydroisoquinolin-1-one
Canonical SMILES	COc1cc2c(cc1OC)CCN(C2=O)C
Standard InCHI	InChI=1S/C12H15NO3/c1-13-5-4-8-6-10(15-2)11(16-3)7-9(8)12(13)14/h6-7H,4-5H2,1-3H3
Standard InCHIKey	BDIZBBGNYDRCCA-UHFFFAOYSA-N
External Identifiers	ChEMBL [CHEMBL504722]; PubChem [303906];
Reference of Component-Ingredient Pair	N/A

Occurrence of the ingredient across TCM components

Component ID	Latin Name	Pinyin Name	Chinese Name
TCMH175	Menispermum dauricum	Bian Fu Ge	è™è è‘›

Ingredient ID: TCMC30
Formula: C15H12O7

Common Name	(+)-Taxifolin
IUPAC Name	(2R,3R)-2-(3,4-dihydroxyphenyl)-3,5,7-trihydroxy-2,3-dihydrochromen-4-one
Canonical SMILES	Oc1cc2O[C@H](c3ccc(c(c3)O)O)[C@H](C(=O)c2c(c1)O)O
Standard InCHI	InChI=1S/C15H12O7/c16-7-4-10(19)12-11(5-7)22-15(14(21)13(12)20)6-1-2-8(17)9(18)3-6/h1-5,14-19,21H/t14-,15+/m0/s1
Standard InCHIKey	CXQWRCVTCMQVQX-LSDHHAIUSA-N
External Identifiers	ChEMBL [CHEMBL66]; PubChem [439533];
Reference of Component-Ingredient Pair	11258977

Occurrence of the ingredient across TCM components

Component ID	Latin Name	Pinyin Name	Chinese Name
TCMH177	Polygonum aviculare	Bian Xu	è¹è“„
TCMH143	Albizia julibrissin	Bei He Huan	åŒ—åˆæ¬¢
TCMH765	Entada phaseoloides	Guo Gang Long Jin Gao	è¿‡å²—é¾™æµ¸è†
TCMH1105	Trollius chinensis	Jin Lian Hua	é‡‘èŽ²èŠ±
TCMH1096	Inula japonica	Jin Fei Cao	é‡‘æ²¸è‰
TCMH1930	Umbilicaria esculenta	Shi Er	çŸ³è€³
TCMH37	Smilax china	Ba Qia	èè‘œ
TCMH1798	Morus alba	Sang Zhi	æ¡‘æž
TCMH1376	Trachelospermum jasminoides	Luo Shi Teng	ç»œçŸ³è—¤
TCMH175	Menispermum dauricum	Bian Fu Ge	è™è è‘›
TCMH1437	Rhododendron dauricum	Man Shan Hong	æ»¡å±±çº¢
TCMH764	Entada phaseoloides	Guo Gang Long	è¿‡å²—é¾™
TCMH1792	Morus alba	Sang Pi	æ¡‘çš®
TCMH1797	Morus alba	Sang Ye	æ¡‘å¶
TCMH2134	Smilax glabra	Tu Fu Ling	åœŸèŒ¯è‹“
TCMH2267	Periploca sepium	Xiang Jia Pi	é¦™åŠ çš®

Ingredient ID: TCMC2106
Formula: C19H21NO4

Common Name	Stepholidine
IUPAC Name	(13aS)-3,9-dimethoxy-6,8,13,13a-tetrahydro-5H-isoquinolino[2,1-b]isoquinoline-2,10-diol
Canonical SMILES	COc1cc2CCN3[C@H](c2cc1O)Cc1c(C3)c(OC)c(cc1)O
Standard InCHI	InChI=1S/C19H21NO4/c1-23-18-8-12-5-6-20-10-14-11(3-4-16(21)19(14)24-2)7-15(20)13(12)9-17(18)22/h3-4,8-9,15,21-22H,5-7,10H2,1-2H3/t15-/m0/s1
Standard InCHIKey	JKPISQIIWUONPB-HNNXBMFYSA-N
External Identifiers	ChEMBL [CHEMBL487387]; PubChem [6917970];
Reference of Component-Ingredient Pair	27688181

Occurrence of the ingredient across TCM components

Component ID	Latin Name	Pinyin Name	Chinese Name
TCMH388	Ziziphus jujuba	Da Zao	å¤§æž£
TCMH1680	Sinomenium acutum	Qing Feng Teng	é’é£Žè—¤
TCMH175	Menispermum dauricum	Bian Fu Ge	è™è è‘›

Ingredient ID: TCMC1734
Formula: C15H12O5

Common Name	Naringenin
IUPAC Name	(2S)-5,7-dihydroxy-2-(4-hydroxyphenyl)-2,3-dihydrochromen-4-one
Canonical SMILES	Oc1ccc(cc1)[C@@H]1CC(=O)c2c(O1)cc(cc2O)O
Standard InCHI	InChI=1S/C15H12O5/c16-9-3-1-8(2-4-9)13-7-12(19)15-11(18)5-10(17)6-14(15)20-13/h1-6,13,16-18H,7H2/t13-/m0/s1
Standard InCHIKey	FTVWIRXFELQLPI-ZDUSSCGKSA-N
External Identifiers	ChEMBL [CHEMBL9352]; PubChem [439246];
Reference of Component-Ingredient Pair	22970652

Occurrence of the ingredient across TCM components

Component ID	Latin Name	Pinyin Name	Chinese Name
TCMH945	Sophora japonica	Huai Zhi	æ§æž
TCMH440	Erigeron breviscapus	Deng Zhan Xi Xin	ç¯ç›ç»†è¾›
TCMH568	Euphorbia hirta	Fei Yang Cao	é£žæ¨è‰
TCMH733	Desmodium styracifolium	Guang Jin Qian Cao	å¹¿é‡‘é’±è‰
TCMH765	Entada phaseoloides	Guo Gang Long Jin Gao	è¿‡å²—é¾™æµ¸è†
TCMH1538	Baphicacanthus cusia	Nan Ban Lan Gen Jin Gao Fen	å—æ¿è“æ ¹æµ¸è†ç²‰
TCMH1105	Trollius chinensis	Jin Lian Hua	é‡‘èŽ²èŠ±
TCMH748	Euonymus alatus	Gui Jian Yu	é¬¼ç®ç¾½
TCMH215	Alpinia katsumadai	Cao Dou Kou Ren	è‰è±†è”»ä»
TCMH1322	Solanum nigrum	Long Kui	é¾™è‘µ
TCMH1930	Umbilicaria esculenta	Shi Er	çŸ³è€³
TCMH37	Smilax china	Ba Qia	èè‘œ
TCMH693	Cudrania cochinchinensis	Gou Ji	ç‹—è„Š
TCMH970	Vitex negundo	Huang Jing Zi	é»„è†å
TCMH1000	Foeniculum vulgare	Hui Xiang	èŒ´é¦™
TCMH1903	Zingiber officinale	Sheng Jiang	ç”Ÿå§œ
TCMH1181	Chrysanthemum morifolium	Ju Hua	èŠèŠ±
TCMH1179	Citri exocarpium rubrum	Ju Hong	æ©˜çº¢
TCMH175	Menispermum dauricum	Bian Fu Ge	è™è è‘›
TCMH132	Scutellaria barbata	Ban Zhi Lian	åŠæžèŽ²
TCMH1184	Citrus reticulata	Ju Pi	æ©˜çš®
TCMH1437	Rhododendron dauricum	Man Shan Hong	æ»¡å±±çº¢
TCMH214	Alpinia katsumadai	Cao Dou Kou	è‰è±†è”»
TCMH764	Entada phaseoloides	Guo Gang Long	è¿‡å²—é¾™
TCMH1734	Homo sapiens	Ren Zhong Bai	äººä¸ç™½
TCMH938	Sophora japonica	Huai Hua	æ§èŠ±
TCMH940	Sophora japonica	Huai Jiao	æ§è§’
TCMH941	Sophora japonica	Huai Mi	æ§ç±³
TCMH1178	Citrus reticulata	Ju He	æ©˜æ ¸
TCMH93	Prunus mume	Bai Mei Hua	ç™½æ¢…èŠ±
TCMH809	Chrysanthemum morifolium	Hang Ju	æèŠ
TCMH1537	Baphicacanthus cusia	Nan Ban Lan Gen	å—æ¿è“æ ¹
TCMH628	Glycyrrhiza uralensis	Gan Cao	ç”˜è‰
TCMH629	Glycyrrhiza uralensis	Gan Cao Fen	ç”˜è‰ç²‰
TCMH630	Glycyrrhiza uralensis	Gan Cao Gan Gao	ç”˜è‰å¹²è†
TCMH631	Glycyrrhiza uralensis	Gan Cao Gan Gao Fen	ç”˜è‰å¹²è†ç²‰
TCMH632	Glycyrrhiza uralensis	Gan Cao Gan Jin Gao	ç”˜è‰å¹²æµ¸è†
TCMH633	Glycyrrhiza uralensis	Gan Cao Gao	ç”˜è‰è†
TCMH634	Glycyrrhiza uralensis	Gan Cao Jie	ç”˜è‰èŠ‚
TCMH635	Glycyrrhiza uralensis	Gan Cao Jin Gao	ç”˜è‰æµ¸è†
TCMH636	Glycyrrhiza uralensis	Gan Cao Liu Jin Gao	ç”˜è‰æµæµ¸è†
TCMH1475	Glycyrrhiza uralensis	Mi Gan Cao	èœœç”˜è‰
TCMH1899	Glycyrrhiza uralensis	Sheng Gan Cao	ç”Ÿç”˜è‰
TCMH253	Citrus aurantium	Cheng Pi	æ©™çš®
TCMH2630	Citrus aurantium	Zhi Shi	æž³å®ž
TCMH2134	Smilax glabra	Tu Fu Ling	åœŸèŒ¯è‹“
TCMH2375	Trigonella foenum-graecum	Yan Hu Lu Ba	ç›èƒ¡èŠ¦å·´
TCMH2710	Homo sapiens	Zi He Che	ç´«æ²³è½¦
TCMH2239	Asarum sieboldii	Xi Xin	ç»†è¾›
TCMH2192	Prunus mume	Wu Mei Rou	ä¹Œæ¢…è‚‰
TCMH2297	Cirsium setosum	Xiao Ji	å°è“Ÿ
TCMH2135	Glycyrrhiza uralensis	Tu Gan Cao	åœŸç”˜è‰
TCMH2191	Prunus mume	Wu Mei	ä¹Œæ¢…
TCMH2613	Citrus aurantium	Zhi Geng	æž³æ¢—
TCMH2618	Citrus aurantium	Zhi Ke	æž³å£³
TCMH2619	Citrus aurantium	Zhi Ke Gan Jin Gao	æž³å£³å¹²æµ¸è†

Properties

Ingredient ID	Formulae	Name	MW	AlogP	MlogP	XlogP	# HBA	# HBD	PSA	# Rotatable Bond	# Ring	# Heacy Atom
TCMC30	C15H12O7	(+)-Taxifolin	304.06	-2.9269	2.34	0.028	2	5	127.45	6	3	22
TCMC571	C12H15NO3	6,7-Dimethoxy-2-Methyl-3,4-Dihydroisoquinolin-1-One	221.11	-0.3689	2.34	0.914	2	0	38.77	5	2	16
TCMC1734	C15H12O5	Naringenin	272.07	-1.8144	2.56	0.897	1	3	86.99	4	3	20
TCMC2106	C19H21NO4	Stepholidine	327.15	-0.7202	3	1.51	1	2	62.16	6	4	24

Download Data

All data can be downloaded by:

→ Selecting data type in the below download table
→ Then click the download button.

Data Section	Select to Download
1. General Information of the Component
2. TCM Prescriptions with the Component
3. Putative Targets
4. Activity & References for Filtering Putative Targets
5. Ingredient Data & Chemical Structure Information (Properties, InChI, InChIkey, SMILES, etc.)

Component: Menispermum dauricum è™è è‘›

Description of the Component

Component ID

Latin Name

English Name

Chinese Pinyin Name

中文名

TCM Properties

TCM Meridians

Therapeutic Class English

Therapeutic Class Chinese

Functions

Toxicity

Geo-authentic habitats (道地产区)

Reference

Barcode ID

Barcode Source

TCM Prescriptions with the Component

Targeted Human Proteins by the Ingredient of Component

Targeted Pathogenic Microbes by the Ingredient of Component

Ingredient Structrues

Ingredient ID: TCMC571

Occurrence of the ingredient across TCM components

Ingredient ID: TCMC30

Occurrence of the ingredient across TCM components

Ingredient ID: TCMC2106

Occurrence of the ingredient across TCM components

Ingredient ID: TCMC1734

Occurrence of the ingredient across TCM components

Properties

Download Data

Component: Menispermum dauricum è™è è‘›