Targeted Human Proteins by the Ingredients of Prescription
References are linked to referred publications via PubMed ID or DOI.There may be multiple activity records for a specific ingredient-target pair.
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| Ingredient ID & Structure | Target ID | Target Name | Target Organism | Activity Records & Reference |
|---|---|---|---|---|
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TCMT27 | Dopamine D1 receptor | Homo sapiens |
Ki: 5.9 (nM), Ref: 19744859 IC50: 12.29 (nM), Ref: 22748706 Ki: 6.23 (nM), Ref: 22748706 Ki: 3.4 (nM), Ref: 23332346 Ki: 12.29 (nM), Ref: 25308766 |
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TCMT38 | Dopamine D2 receptor | Homo sapiens |
Ki: 974 (nM), Ref: 19744859 IC50: 105.41 (nM), Ref: 22748706 Ki: 56.17 (nM), Ref: 22748706 Ki: 11 (nM), Ref: 23332346 Ki: 105.41 (nM), Ref: 25308766 IC50: 4380 (nM), Ref: 25308766 |
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TCMT648 | Dopamine D4 receptor | Homo sapiens |
Ki: 3748 (nM), Ref: 19744859 |
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TCMT649 | Dopamine D5 receptor | Homo sapiens |
Ki: 4.4 (nM), Ref: 19744859 |
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TCMT46 | Coagulation factor III | Homo sapiens |
IC50: 104.58 (nM), Ref: 23199480 |
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TCMT651 | Dopamine D3 receptor | Homo sapiens |
Ki: 90.02 (nM), Ref: 25308766 Ki: 30 (nM), Ref: 27032890 |
 |
TCMT254 | Carbonyl reductase [NADPH] 1 | Homo sapiens |
Ki: 3430 (nM), Ref: 19097799 |
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TCMT65 | Estradiol 17-beta-dehydrogenase 1 | Homo sapiens |
IC50: 4960 (nM), Ref: 18533708 |
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TCMT156 | Cytochrome P450 19A1 | Homo sapiens |
IC50: 2.9 (nM), Ref: 20413308 IC50: 230 (nM), Ref: 22115839 IC50: 230 (nM), Ref: 23142320 IC50: 1200 (nM), Ref: 23994869 IC50: 3300 (nM), Ref: 24074257 IC50: 1200 (nM), Ref: 24992702 IC50: 5100 (nM), Ref: 27155469 IC50: 1000 (nM), Ref: 27155469 |
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TCMT257 | Cytochrome P450 1B1 | Homo sapiens |
IC50: 3656 (nM), Ref: 20696580 |
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TCMT142 | Carbonic anhydrase IV | Homo sapiens |
Ki: 79.5 (nM), Ref: 26498393 |
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TCMT138 | Carbonic anhydrase VII | Homo sapiens |
Ki: 4.3 (nM), Ref: 26498393 |
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TCMT136 | Carbonic anhydrase XII | Homo sapiens |
Ki: 44.3 (nM), Ref: 26498393 |