Component: Baphicacanthus cusia 南板蓝根浸膏粉


Description of the Component

Component ID
TCMH1538
Latin Name
Baphicacanthus cusia
English Name
Indigowoad root
Chinese Pinyin Name
Nan Ban Lan Gen Jin Gao Fen
中文名
南板蓝根浸膏粉
TCM Properties
TCM Meridians
Therapeutic Class English
Therapeutic Class Chinese
Functions
Toxicity
NA
Geo-authentic habitats (道地产区)
NA
Reference
CFDA
Barcode ID
ITSAM1599-14
Barcode Source
BOLDSYSTEMS

TCM Prescriptions with the Component

Prescription ID Prescription English Name Prescription Chinese Name
TCMFx3206 Fu Fang Xiao Er Tui Re Shuan 复方小儿退热栓

Targeted Human Proteins by the Ingredient of Component

Target ID Gene Symbol Target Name Target Class Uniprot ID
TCMT1 EHMT2 Histone-lysine N-methyltransferase, H3 lysine-9 specific 3 Transferase Q96KQ7
TCMT11 HIF1A Hypoxia-inducible factor 1 alpha Transcription factor Q16665
TCMT125 GBA Beta-glucocerebrosidase Hydrolase P04062
TCMT126 TERT Telomerase reverse transcriptase Transferase O14746
TCMT13 APEX1 DNA-(apurinic or apyrimidinic site) lyase Lyase P27695
TCMT130 ALOX5 Arachidonate 5-lipoxygenase Oxidoreductase P09917
TCMT131 ACHE Acetylcholinesterase Hydrolase P22303
TCMT132 BCHE Butyrylcholinesterase Hydrolase P06276
TCMT133 CA1 Carbonic anhydrase I Lyase P00915
TCMT134 CA2 Carbonic anhydrase II Lyase P00918
TCMT135 CA14 Carbonic anhydrase XIV Lyase Q9ULX7
TCMT136 CA12 Carbonic anhydrase XII Lyase O43570
TCMT137 CA9 Carbonic anhydrase IX Lyase Q16790
TCMT138 CA7 Carbonic anhydrase VII Lyase P43166
TCMT139 CA6 Carbonic anhydrase VI Lyase P23280
TCMT140 CA5B Carbonic anhydrase VB Lyase Q9Y2D0
TCMT141 CA5A Carbonic anhydrase VA Lyase P35218
TCMT142 CA4 Carbonic anhydrase IV Lyase P22748
TCMT143 CA3 Carbonic anhydrase III Lyase P07451
TCMT150 RORC Nuclear receptor ROR-gamma Nuclear receptor P51449
TCMT156 CYP19A1 Cytochrome P450 19A1 Oxidoreductase P11511
TCMT162 UGT1A1 UDP-glucuronosyltransferase 1-1 Transferase P22309
TCMT164 PTGS1 Cyclooxygenase-1 Oxidoreductase P23219
TCMT17 POLB DNA polymerase beta Transferase P06746
TCMT186 MAOB Monoamine oxidase B Oxidoreductase P27338
TCMT187 AR Androgen Receptor Nuclear receptor P10275
TCMT191 STAT3 Signal transducer and activator of transcription 3 Transcription factor P40763
TCMT2 MAPT Microtubule-associated protein tau Unclassified P10636
TCMT208 MAOA Monoamine oxidase A Oxidoreductase P21397
TCMT211 CES1 Acyl coenzyme A:cholesterol acyltransferase Transferase P23141
TCMT215 CYP1A1 Cytochrome P450 1A1 Oxidoreductase P04798
TCMT219 CYP1A2 Cytochrome P450 1A2 Oxidoreductase P05177
TCMT223 AKR1B1 Aldose reductase Oxidoreductase P15121
TCMT236 ESR2 Estrogen receptor beta Nuclear receptor Q92731
TCMT237 SLC5A1 Sodium/glucose cotransporter 1 Transporter P13866
TCMT238 SLC5A2 Sodium/glucose cotransporter 2 Transporter P31639
TCMT239 PIM1 Serine/threonine-protein kinase PIM1 Kinase P11309
TCMT240 AMY1A Salivary alpha-amylase Unclassified P04745
TCMT248 CXCL8 Interleukin-8 Unclassified P10145
TCMT254 CBR1 Carbonyl reductase [NADPH] 1 Oxidoreductase P16152
TCMT257 CYP1B1 Cytochrome P450 1B1 Oxidoreductase Q16678
TCMT260 FLT3 Tyrosine-protein kinase receptor FLT3 Kinase P36888
TCMT265 GSK3B Glycogen synthase kinase-3 beta Kinase P49841
TCMT273 NR1H4 Bile acid receptor FXR Nuclear receptor Q96RI1
TCMT276 SLCO2B1 Solute carrier organic anion transporter family member 2B1 Transporter O94956
TCMT277 SLCO1B3 Solute carrier organic anion transporter family member 1B3 Transporter Q9NPD5
TCMT278 SLCO1B1 Solute carrier organic anion transporter family member 1B1 Transporter Q9Y6L6
TCMT280 AKR1B10 Aldo-keto reductase family 1 member B10 Oxidoreductase O60218
TCMT281 DPP4 Dipeptidyl peptidase IV Unclassified P27487
TCMT3 ALOX15 Arachidonate 15-lipoxygenase Oxidoreductase P16050
TCMT30 PTGS2 Cyclooxygenase-2 Oxidoreductase P35354
TCMT31 CYP2C19 Cytochrome P450 2C19 Oxidoreductase P33261
TCMT33 CYP3A4 Cytochrome P450 3A4 Oxidoreductase P08684
TCMT336 IDO1 Indoleamine 2,3-dioxygenase Oxidoreductase P14902
TCMT34 CYP2D6 Cytochrome P450 2D6 Oxidoreductase P10635
TCMT341 NR1I2 Pregnane X receptor Nuclear receptor O75469
TCMT39 PDE5A Phosphodiesterase 5A Hydrolase O76074
TCMT41 IDH1 Isocitrate dehydrogenase [NADP] cytoplasmic Oxidoreductase O75874
TCMT42 KMT2A Histone-lysine N-methyltransferase MLL Transferase Q03164
TCMT423 EGFR Epidermal growth factor receptor erbB1 Kinase P00533
TCMT44 GLO1 Glyoxalase I Lyase Q04760
TCMT46 F3 Coagulation factor III Unclassified P13726
TCMT558 TOP2A DNA topoisomerase II alpha Isomerase P11388
TCMT6 NFKB1 Nuclear factor NF-kappa-B p105 subunit Transcription factor P19838
TCMT619 HSP90AA1 Heat shock protein HSP 90-alpha Unclassified P07900
TCMT63 PPARA Peroxisome proliferator-activated receptor alpha Nuclear receptor Q07869
TCMT64 PPARD Peroxisome proliferator-activated receptor delta Nuclear receptor Q03181
TCMT65 HSD17B1 Estradiol 17-beta-dehydrogenase 1 Oxidoreductase P14061
TCMT66 HSD17B2 Estradiol 17-beta-dehydrogenase 2 Oxidoreductase P37059
TCMT67 PPARG Peroxisome proliferator-activated receptor gamma Nuclear receptor P37231
TCMT689 TGM2 Protein-glutamine gamma-glutamyltransferase Transferase P21980
TCMT8 KDM4E Lysine-specific demethylase 4D-like Oxidoreductase B2RXH2
TCMT80 MAPK1 MAP kinase ERK2 Kinase P28482
TCMT81 ALOX12 Arachidonate 12-lipoxygenase Oxidoreductase P18054
TCMT82 ESR1 Estrogen receptor alpha Nuclear receptor P03372
TCMT822 FUT7 Alpha-(1,3)-fucosyltransferase 7 Transferase Q11130
TCMT827 NQO1 Quinone reductase 1) Oxidoreductase P15559
TCMT87 CYP2C9 Cytochrome P450 2C9 Oxidoreductase P11712
TCMT99 SHBG Testis-specific androgen-binding protein Unclassified P04278


Targeted Pathogenic Microbes by the Ingredient of Component

Target ID Target Name
TCMT1090 Human immunodeficiency virus type 1 integrase
TCMT1092 Fatty acid synthase
TCMT1099 Neuraminidase
TCMT1136 Neuraminidase
TCMT1176 Streptococcus pneumoniae
TCMT1178 Actinomyces viscosus
TCMT1181 Mycobacterium tuberculosis H37Ra
TCMT1218 Staphylococcus aureus
TCMT1221 Human herpesvirus 4
TCMT1226 Klebsiella pneumoniae
TCMT1229 Enterococcus faecalis
TCMT1231 Human herpesvirus 1 strain KOS
TCMT1243 Aspergillus flavus
TCMT1246 Escherichia coli
TCMT1251 Candida albicans
TCMT1255 Human immunodeficiency virus 1
TCMT1284 Penicillium expansum
TCMT1353 Plasmodium yoelii
TCMT1438 Plasmodium falciparum
TCMT1439 Mycobacterium smegmatis
TCMT1442 Leishmania donovani
TCMT1455 Mycobacterium tuberculosis H37Rv
TCMT1458 Filobasidiella neoformans
TCMT1463 Mycobacterium tuberculosis
TCMT1465 Entamoeba histolytica

Ingredient Structrues

Ingredient ID: TCMC983
Formula: C15H10O4

Ingredient ID: TCMC860
Formula: C23H13N3O2

Ingredient ID: TCMC855
Formula: C16H12O5

Ingredient ID: TCMC811
Formula: C16H12O5

Ingredient ID: TCMC804
Formula: C30H48O3

Ingredient ID: TCMC801
Formula: C29H50O

Ingredient ID: TCMC791
Formula: C40H56

Ingredient ID: TCMC721
Formula: C6H14N4O2

Ingredient ID: TCMC309
Formula: C14H17NO6

Ingredient ID: TCMC2233
Formula: C21H20O10

Ingredient ID: TCMC2197
Formula: C11H12N2O2

Ingredient ID: TCMC2196
Formula: C15H8N2O2

Ingredient ID: TCMC2190
Formula: C7H7NO2

Ingredient ID: TCMC2188
Formula: C17H14O7

Ingredient ID: TCMC2158
Formula: C12H17N4OS

Ingredient ID: TCMC1811
Formula: C8H7NO

Ingredient ID: TCMC1734
Formula: C15H12O5

Ingredient ID: TCMC1496
Formula: C18H30O2

Ingredient ID: TCMC1403
Formula: C21H20O11

Ingredient ID: TCMC1396
Formula: C16H10N2O2

Ingredient ID: TCMC1377
Formula: C8H5NO2

Ingredient ID: TCMC1370
Formula: C16H10N2O2

Ingredient ID: TCMC1202
Formula: C7H6O5

Ingredient ID: TCMC1186
Formula: C16H12O4

Ingredient ID: TCMC1072
Formula: C27H42O3

Ingredient ID: TCMC1063
Formula: C45H72O16

Ingredient ID: TCMC1024
Formula: C6H9N3O2

Properties

Ingredient ID Formulae Name MW AlogP MlogP XlogP # HBA # HBD PSA # Rotatable Bond # Ring # Heacy Atom Lipinski RO5 Violation
TCMC309 C14H17NO6 2-(Hydroxymethyl)-6-(1H-Indol-3-Yloxy)Oxane-3,4,5-Triol 295.11 -2.6276 2.23 0.379 6 5 115.17 7 3 21 0
TCMC721 C6H14N4O2 Arginine 174.11 -2.1807 1.46 -2.924 6 5 125.22 9 0 12 0
TCMC791 C40H56 Beta Carotene 536.44 8.935 5.86 14.734 0 0 0 20 2 40 1
TCMC801 C29H50O Beta-Sitosterol 414.39 1.3 4.54 11.595 1 1 20.23 13 4 30 1
TCMC804 C30H48O3 Betulinic Acid 456.36 2.3495 4.43 9.407 3 2 57.53 10 5 33 1
TCMC811 C16H12O5 Biochanin 284.07 -1.6391 2.67 2.031 1 2 75.99 5 3 21 0
TCMC855 C16H12O5 Calycosin 284.07 -1.6391 2.67 2.031 1 2 75.99 5 3 21 0
TCMC860 C23H13N3O2 Candidine 363.1 -1.4589 3.44 6.186 5 1 61.77 0 6 28 1
TCMC983 C15H10O4 Daidzein 254.06 -1.5873 2.67 2.475 1 2 66.76 3 3 19 0
TCMC1024 C6H9N3O2 D-Histidine 155.07 -1.3116 1.57 -3.134 5 3 92 5 1 11 0
TCMC1063 C45H72O16 Dioscin 868.48 -3.9636 4.65 2.836 16 8 235.68 21 9 61 2
TCMC1072 C27H42O3 Disogenin 414.31 0.2771 4.1 6.041 3 1 38.69 5 6 30 1
TCMC1186 C16H12O4 Formononetin 268.07 -1.1788 2.78 2.994 1 1 55.76 4 3 20 0
TCMC1202 C7H6O5 Gallic Acid 170.02 -1.6207 1.68 0.002 2 4 97.99 5 1 12 0
TCMC1370 C16H10N2O2 Indigo 262.07 -1.7942 2.78 4.628 4 2 58.2 0 4 20 0
TCMC1377 C8H5NO2 Isatin 147.03 -0.8986 2.01 1.653 3 1 46.17 0 2 11 0
TCMC1396 C16H10N2O2 Isoindigo 262.07 -0.0866 2.78 4.42 4 2 65.18 2 4 20 0
TCMC1403 C21H20O11 Isoorientin 448.1 -4.5805 2.56 -1.042 6 8 197.37 11 4 32 1
TCMC1496 C18H30O2 Linolenic Acid 278.22 -0.0979 3.22 7.538 2 1 37.3 15 0 20 2
TCMC1734 C15H12O5 Naringenin 272.07 -1.8144 2.56 0.897 1 3 86.99 4 3 20 0
TCMC1811 C8H7NO Oxindole 133.05 -0.0468 2.12 2.149 2 1 32.59 1 2 10 0
TCMC2158 C12H17N4OS Thiamine 265.11 -2.3748 2.12 0.641 4 3 100.59 7 2 18 0
TCMC2188 C17H14O7 Tricin 330.07 -1.9881 2.56 0.679 1 3 105.45 8 3 24 0
TCMC2190 C7H7NO2 Trigonelline 137.05 -2.2592 1.9 0.283 2 0 44.01 3 1 10 0
TCMC2196 C15H8N2O2 Tryptanthrin 248.06 -0.8639 2.67 3.473 4 0 49.74 0 4 19 0
TCMC2197 C11H12N2O2 Tryptophan 204.09 -1.5048 2.23 -0.96 4 3 79.11 5 2 15 0
TCMC2233 C21H20O10 Vitexin 432.11 -4.1202 2.67 -0.508 6 7 177.14 10 4 31 1

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