Component: Spiraea japonica 绣线菊


Description of the Component

Component ID
TCMH2332
Latin Name
Spiraea japonica
English Name
Japanese spiraea
Chinese Pinyin Name
Xiu Xian Ju
中文名
绣线菊
TCM Properties
TCM Meridians
Therapeutic Class English
Therapeutic Class Chinese
Functions
Toxicity
NA
Geo-authentic habitats (道地产区)
NA
Reference
Chinese Pharmacopoeia (2015)
Barcode ID
MKTRT925-13
Barcode Source
BOLDSYSTEMS

TCM Prescriptions with the Component

Prescription ID Prescription English Name Prescription Chinese Name
TCMFx7119 Bi Kang Tablets 鼻康片

Targeted Human Proteins by the Ingredient of Component

Target ID Gene Symbol Target Name Target Class Uniprot ID
TCMT1 EHMT2 Histone-lysine N-methyltransferase, H3 lysine-9 specific 3 Transferase Q96KQ7
TCMT11 HIF1A Hypoxia-inducible factor 1 alpha Transcription factor Q16665
TCMT17 POLB DNA polymerase beta Transferase P06746
TCMT2 MAPT Microtubule-associated protein tau Unclassified P10636
TCMT265 GSK3B Glycogen synthase kinase-3 beta Kinase P49841
TCMT31 CYP2C19 Cytochrome P450 2C19 Oxidoreductase P33261
TCMT33 CYP3A4 Cytochrome P450 3A4 Oxidoreductase P08684
TCMT34 CYP2D6 Cytochrome P450 2D6 Oxidoreductase P10635
TCMT689 TGM2 Protein-glutamine gamma-glutamyltransferase Transferase P21980
TCMT8 KDM4E Lysine-specific demethylase 4D-like Oxidoreductase B2RXH2
TCMT80 MAPK1 MAP kinase ERK2 Kinase P28482
TCMT87 CYP2C9 Cytochrome P450 2C9 Oxidoreductase P11712


Targeted Pathogenic Microbes by the Ingredient of Component

Target ID Target Name
TCMT1346 Helicobacter pylori
TCMT1438 Plasmodium falciparum

Ingredient Structrues

Ingredient ID: TCMC2490
Formula: C23H20O6

Ingredient ID: TCMC2026
Formula: C23H22O6

Ingredient ID: TCMC1371
Formula: C16H10N2O2

Ingredient ID: TCMC1370
Formula: C16H10N2O2

Ingredient ID: TCMC1001
Formula: C23H22O6

Properties

Ingredient ID Formulae Name MW AlogP MlogP XlogP # HBA # HBD PSA # Rotatable Bond # Ring # Heacy Atom Lipinski RO5 Violation
TCMC1001 C23H22O6 Deguelin 394.14 0.0487 3.33 2.551 1 0 63.22 6 5 29 0
TCMC1370 C16H10N2O2 Indigo 262.07 -1.7942 2.78 4.628 4 2 58.2 0 4 20 0
TCMC1371 C16H10N2O2 Indirubin 262.07 -0.9404 2.78 4.524 4 2 61.69 1 4 20 0
TCMC2026 C23H22O6 Rotenone 394.14 0.1527 3.33 2.076 1 0 63.22 6 5 29 0
TCMC2490 C23H20O6 Dehydrodeguelin 392.13 0.0692 3.33 3.204 1 0 63.22 6 5 29 0

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1. General Information of the Component  
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3. Putative Targets  
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5. Ingredient Data & Chemical Structure Information (Properties, InChI, InChIkey, SMILES, etc.)