Component ID |
TCMH1814 |
Latin Name |
Sophora subprostrata |
English Name |
Tonkin sophora root |
Chinese Pinyin Name |
Shan Dou Gen |
中文名 |
山豆根 |
TCM Properties |
Cold,Bitter |
TCM Meridians |
Lung,Stomach |
Therapeutic Class English |
Heat clearence |
Therapeutic Class Chinese |
清热 |
Functions |
remove toxic heat, promote the subsidence of swelling, and soothe the sore throat |
Toxicity |
NA |
Geo-authentic habitats (道地产区) |
Guangxi Province |
Reference |
Chinese Pharmacopoeia (2015) |
Barcode ID |
|
Barcode Source |
Prescription ID | Prescription English Name | Prescription Chinese Name |
---|---|---|
TCMFx3615 | Bi Yan Ling Tablets | 鼻咽灵片 |
TCMFx1169 | Bi Yan Ling Tablet | 鼻咽灵片 |
TCMFx3765 | Bing Mei Shang Qing Pills | 冰梅上清丸 |
TCMF2073 | Danger Relieving Decoction | |
TCMFx7188 | Fu Fang Liang Mian Zhen Han Tablets | 复方两面针含片 |
TCMFx3798 | Fu Fang Mu Ji Granules | 复方木鸡颗粒 |
TCMF785 | Fu Fang Yi Gan Pills | 复方益肝丸 |
TCMFx3674 | Gan Yan Ling Zhu She Oral Liquid | 肝炎灵注射液 |
TCMFx858 | Gui Lin Xi Gua Shuang | 桂林西瓜霜 |
TCMFx4109 | Gui Lin Xi Gua Shuang | 桂林西瓜霜 |
TCMFx4116 | Gui Lin Xi Gua Shuang Capsules | 桂林西瓜霜胶囊 |
TCMFx7058 | Gui Lin Xi Gua Shuang Han Tablets | 桂林西瓜霜含片 |
TCMFx1042 | Hou Ji Ling Capsule | 喉疾灵胶囊 |
TCMFx4505 | Hou Ji Ling Capsules | 喉疾灵胶囊 |
TCMFx4515 | Hou Ji Ling Tablets | 喉疾灵片 |
TCMFx4542 | Hou Tong Jie Du Pills | 喉痛解毒丸 |
TCMF4566 | Hou Tong Tablets | 喉痛片 |
TCMF4040 | Kang Bian Tao Xian Yan Recipe | 抗扁桃腺炎合剂 |
TCMF4049 | Kang Bing Du Granules | 抗病毒颗粒 |
TCMFx22 | Kou Yan Qing Pills | 口咽清丸 |
TCMFx4957 | Lv Pao Powder | 绿袍散 |
TCMF5231 | Qing Ge Pills | 清膈丸 |
TCMF1089 | Qing Ge Pills | 清膈丸 |
TCMF7424 | Qing Liang Powder | 清凉散 |
TCMF5675 | Qing Re Yang Yin Pills | 清热养阴丸 |
TCMF68 | Qing Yan Run Hou Pills | 清咽润喉丸 |
TCMF4958 | Qing Yan Run Hou Pills | 清咽润喉丸 |
TCMF4967 | Qing Yan Yi Huo Pills | 清咽抑火丸 |
TCMFx5006 | Qing Yu Bi Wen Dan | 庆余辟瘟丹 |
TCMFx490 | Qing Yu Pi Wen Dan | 庆余辟瘟丹 |
TCMF5042 | Qiu Zao Gan Mao Granules | 秋燥感冒颗粒 |
TCMF5721 | Ruan Jian Yao Decoction | 软坚药水 |
TCMFx5713 | Ruan Shi Shang Qing Pills | 阮氏上清丸 |
TCMFx7011 | Shang Granulesng Spray | 伤科灵喷雾剂 |
TCMFx5041 | She Shang Jie Du Tablets | 蛇伤解毒片 |
TCMFx7211 | Shu Yan Qing Spray | 舒咽清喷雾剂 |
TCMF7132 | Shuang Liao Hou Feng Han Tablets | 双料喉风含片 |
TCMF5693 | Shuang Liao Hou Feng Powder | 双料喉风散 |
TCMF5156 | Tou Biao Hui Chun Pills | 透表回春丸 |
TCMFx6690 | Yun Xiang Jing | 云香精 |
Target ID | Gene Symbol | Target Name | Target Class | Uniprot ID |
---|---|---|---|---|
TCMT1 | EHMT2 | Histone-lysine N-methyltransferase, H3 lysine-9 specific 3 | Transferase | Q96KQ7 |
TCMT133 | CA1 | Carbonic anhydrase I | Lyase | P00915 |
TCMT134 | CA2 | Carbonic anhydrase II | Lyase | P00918 |
TCMT136 | CA12 | Carbonic anhydrase XII | Lyase | O43570 |
TCMT138 | CA7 | Carbonic anhydrase VII | Lyase | P43166 |
TCMT142 | CA4 | Carbonic anhydrase IV | Lyase | P22748 |
TCMT150 | RORC | Nuclear receptor ROR-gamma | Nuclear receptor | P51449 |
TCMT156 | CYP19A1 | Cytochrome P450 19A1 | Oxidoreductase | P11511 |
TCMT162 | UGT1A1 | UDP-glucuronosyltransferase 1-1 | Transferase | P22309 |
TCMT2 | MAPT | Microtubule-associated protein tau | Unclassified | P10636 |
TCMT223 | AKR1B1 | Aldose reductase | Oxidoreductase | P15121 |
TCMT236 | ESR2 | Estrogen receptor beta | Nuclear receptor | Q92731 |
TCMT237 | SLC5A1 | Sodium/glucose cotransporter 1 | Transporter | P13866 |
TCMT238 | SLC5A2 | Sodium/glucose cotransporter 2 | Transporter | P31639 |
TCMT240 | AMY1A | Salivary alpha-amylase | Unclassified | P04745 |
TCMT276 | SLCO2B1 | Solute carrier organic anion transporter family member 2B1 | Transporter | O94956 |
TCMT277 | SLCO1B3 | Solute carrier organic anion transporter family member 1B3 | Transporter | Q9NPD5 |
TCMT278 | SLCO1B1 | Solute carrier organic anion transporter family member 1B1 | Transporter | Q9Y6L6 |
TCMT280 | AKR1B10 | Aldo-keto reductase family 1 member B10 | Oxidoreductase | O60218 |
TCMT31 | CYP2C19 | Cytochrome P450 2C19 | Oxidoreductase | P33261 |
TCMT33 | CYP3A4 | Cytochrome P450 3A4 | Oxidoreductase | P08684 |
TCMT34 | CYP2D6 | Cytochrome P450 2D6 | Oxidoreductase | P10635 |
TCMT423 | EGFR | Epidermal growth factor receptor erbB1 | Kinase | P00533 |
TCMT6 | NFKB1 | Nuclear factor NF-kappa-B p105 subunit | Transcription factor | P19838 |
TCMT63 | PPARA | Peroxisome proliferator-activated receptor alpha | Nuclear receptor | Q07869 |
TCMT64 | PPARD | Peroxisome proliferator-activated receptor delta | Nuclear receptor | Q03181 |
TCMT65 | HSD17B1 | Estradiol 17-beta-dehydrogenase 1 | Oxidoreductase | P14061 |
TCMT66 | HSD17B2 | Estradiol 17-beta-dehydrogenase 2 | Oxidoreductase | P37059 |
TCMT67 | PPARG | Peroxisome proliferator-activated receptor gamma | Nuclear receptor | P37231 |
TCMT8 | KDM4E | Lysine-specific demethylase 4D-like | Oxidoreductase | B2RXH2 |
TCMT80 | MAPK1 | MAP kinase ERK2 | Kinase | P28482 |
TCMT82 | ESR1 | Estrogen receptor alpha | Nuclear receptor | P03372 |
TCMT87 | CYP2C9 | Cytochrome P450 2C9 | Oxidoreductase | P11712 |
Target ID | Target Name |
---|---|
TCMT1099 | Neuraminidase |
Ingredient ID: TCMC983
Formula: C15H10O4
Ingredient ID: TCMC7337
Formula: C15H24N2O2
Ingredient ID: TCMC7249
Formula: C48H78O19
Ingredient ID: TCMC7129
Formula: C48H74O20
Ingredient ID: TCMC6433
Formula: C30H48O4
Ingredient ID: TCMC6178
Formula: C30H50O4
Ingredient ID: TCMC6146
Formula: C30H50O3
Ingredient ID: TCMC6144
Formula: C30H50O4
Ingredient ID: TCMC5962
Formula: C15H24N2O2
Ingredient ID: TCMC5959
Formula: C30H50O4
Ingredient ID: TCMC5241
Formula: C30H50O2
Ingredient ID: TCMC4931
Formula: C15H20N2O
Ingredient ID: TCMC4862
Formula: C30H34O4
Ingredient ID: TCMC4861
Formula: C30H34O4
Ingredient ID: TCMC4860
Formula: C30H36O4
Ingredient ID: TCMC4531
Formula: C31H52O4
Ingredient ID: TCMC4139
Formula: C48H76O18
Ingredient ID: TCMC4056
Formula: C15H22N2O2
Ingredient ID: TCMC4055
Formula: C15H20N2O
Ingredient ID: TCMC3966
Formula: C29H50O
Ingredient ID: TCMC3949
Formula: C47H76O17
Ingredient ID: TCMC3923
Formula: C22H22O10
Ingredient ID: TCMC3843
Formula: C30H36O4
Ingredient ID: TCMC3707
Formula: C30H46O5
Ingredient ID: TCMC3599
Formula: C15H22N2O2
Ingredient ID: TCMC3413
Formula: C15H22N2O
Ingredient ID: TCMC3408
Formula: C30H50O3
Ingredient ID: TCMC3311
Formula: C15H24N2O
Ingredient ID: TCMC1963
Formula: C17H14O5
Ingredient ID: TCMC1629
Formula: C16H12O5
Ingredient ID | Formulae | Name | MW | AlogP | MlogP | XlogP | # HBA | # HBD | PSA | # Rotatable Bond | # Ring | # Heacy Atom | Lipinski RO5 Violation |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
TCMC983 | C15H10O4 | Daidzein | 254.06 | -1.5873 | 2.67 | 2.475 | 1 | 2 | 66.76 | 3 | 3 | 19 | 0 |
TCMC1629 | C16H12O5 | 284.07 | -1.4161 | 2.67 | 1.797 | 0 | 1 | 57.15 | 1 | 5 | 21 | 0 | |
TCMC1963 | C17H14O5 | Pterocarpin | 298.08 | -1.0076 | 2.78 | 2.316 | 0 | 0 | 46.15 | 2 | 5 | 22 | 0 |
TCMC3311 | C15H24N2O | Matrine | 249.1966884 | -3.3629 | 2.78 | 1.222 | 2 | 1 | 24.75 | 0 | 4 | 18 | 0 |
TCMC3408 | C30H50O3 | Soyasapogenol B | 458.3759955 | 1.3478 | 4.43 | 8.336 | 3 | 3 | 60.69 | 1 | 5 | 33 | 1 |
TCMC3413 | C15H22N2O | Sophocarpine | 247.1810384 | -2.205 | 2.78 | 1.111 | 2 | 1 | 24.75 | 0 | 4 | 18 | 0 |
TCMC3599 | C15H22N2O2 | Oxysophocarpine | 262.1681279 | -1.153 | 2.67 | 0.589 | 2 | 0 | 43.37 | 0 | 4 | 19 | 0 |
TCMC3707 | C30H46O5 | Melilotigenin | 485.3266995 | 0.0075 | 4.21 | 5.176 | 5 | 2 | 97.66 | 2 | 5 | 35 | 1 |
TCMC3843 | C30H36O4 | Sophoranone | 460.2613596 | 4.2781 | 4.32 | 6.27 | 1 | 2 | 66.76 | 7 | 3 | 34 | 1 |
TCMC3923 | C22H22O10 | Α-Maackiain-Β-D-Glucoside | 446.1212969 | -3.163 | 2.78 | 0.689 | 5 | 4 | 136.3 | 3 | 6 | 32 | 0 |
TCMC3949 | C47H76O17 | Soyasaponinii | 911.5004259 | -3.4578 | 4.76 | 3.918 | 17 | 9 | 277.58 | 8 | 8 | 64 | 2 |
TCMC3966 | C29H50O | Sitosterol,Β-Sitosterol | 414.3861662 | 1.3 | 4.54 | 11.595 | 1 | 1 | 20.23 | 6 | 4 | 30 | 1 |
TCMC4055 | C15H20N2O | Sophoramine | 245.1653883 | -2.5132 | 2.78 | 0.508 | 2 | 1 | 21.51 | 0 | 4 | 18 | 0 |
TCMC4056 | C15H22N2O2 | N-Oxysophocarpine | 262.1681279 | -1.153 | 2.67 | 0.589 | 2 | 0 | 43.37 | 0 | 4 | 19 | 0 |
TCMC4139 | C48H76O18 | Dehydrosoyasaponini | 939.4953406 | -3.7492 | 4.76 | 3.068 | 18 | 9 | 294.65 | 9 | 8 | 66 | 2 |
TCMC4531 | C31H52O4 | Docosyl Caffeate | 488.3865601 | -6.3477 | 4.43 | 13.054 | 2 | 2 | 66.76 | 24 | 1 | 35 | 2 |
TCMC4860 | C30H36O4 | Sophoradin | 460.2613596 | 4.3486 | 4.32 | 7.174 | 1 | 3 | 77.76 | 9 | 2 | 34 | 1 |
TCMC4861 | C30H34O4 | Sophoradochromene | 458.2457096 | 3.8393 | 4.32 | 7.104 | 1 | 2 | 66.76 | 7 | 3 | 34 | 1 |
TCMC4862 | C30H34O4 | Sophoranochromene | 458.2457096 | 3.7688 | 4.32 | 6.2 | 1 | 1 | 55.76 | 5 | 4 | 34 | 1 |
TCMC4931 | C15H20N2O | Anagyrine | 245.1653883 | -3.25 | 2.78 | 0.508 | 2 | 1 | 21.51 | 0 | 4 | 18 | 0 |
TCMC5241 | C30H50O2 | Sophoradiol | 442.3810808 | 2.4385 | 4.54 | 9.039 | 2 | 2 | 40.46 | 0 | 5 | 32 | 1 |
TCMC5959 | C30H50O4 | Soyasapogenol A | 474.3709101 | 0.7747 | 4.32 | 7.102 | 4 | 4 | 80.92 | 1 | 5 | 34 | 1 |
TCMC5962 | C15H24N2O2 | Sophoranol | 265.191603 | -3.802 | 2.67 | 0.312 | 3 | 2 | 44.98 | 0 | 4 | 19 | 0 |
TCMC6144 | C30H50O4 | Abrisapogenol E | 474.3709101 | 0.2571 | 4.32 | 6.571 | 4 | 4 | 80.92 | 2 | 5 | 34 | 1 |
TCMC6146 | C30H50O3 | Abrisapogenol D | 458.3759955 | 1.3478 | 4.43 | 7.274 | 3 | 3 | 60.69 | 1 | 5 | 33 | 1 |
TCMC6178 | C30H50O4 | Abrisapogenol C | 474.3709101 | 0.7747 | 4.32 | 7.102 | 4 | 4 | 80.92 | 1 | 5 | 34 | 1 |
TCMC6433 | C30H48O4 | Wistariasapogenol A | 472.35526 | 0.4764 | 4.32 | 5.964 | 4 | 3 | 77.76 | 2 | 5 | 34 | 1 |
TCMC7129 | C48H74O20 | Abrisaponin I | 968.4616947 | -5.3088 | 4.54 | 0.515 | 20 | 9 | 334.78 | 10 | 8 | 68 | 2 |
TCMC7249 | C48H78O19 | Soyasaponin A3 | 957.5059052 | -4.5416 | 4.65 | 2.441 | 19 | 11 | 318.04 | 9 | 8 | 67 | 2 |
TCMC7337 | C15H24N2O2 | Oxymatrine | 264.183778 | -2.3109 | 2.67 | 0.7 | 2 | 0 | 43.37 | 0 | 4 | 19 | 0 |