TCM Prescription: Hou Tong Jie Du Pills



Prescription Description
Prescription IDTCMFx4542
Pinyin NameHou Tong Jie Du Wan
Chinese Name喉痛解毒丸
English NameHou Tong Jie Du Pills
Function Description喉痹, 乳蛾, 无名肿毒, 口疮
IndicationsTonsillitis disorder, Pharyngitis, Aphtha, Tonsillitis
Disease ICD-11 Category SC93 [Tonsillitis disorder (TM1), 乳蛾 (TM1) ];
CA0Z [Upper respiratory tract disorders, unspecified, 上呼吸道疾患,未特指的 ];
DA01.10 [Oral aphthae or aphtha-like ulceration, 口腔阿弗他溃疡或阿弗他样溃疡 ];
Human Tissues Associated with IndicationLung, Liver, Spleen
ReferenceCFDA
Reference Book/linkhttp://samr.cfda.gov.cn/WS01/CL0001/
Prescription Components
Component ID Latin Name Chinese Name Component Quantity Barcode
TCMH1573 Bovis calculus 牛黄 TCMH1573
TCMH183 Dryobalanops aromatica 冰片 TCMH183 GBVK4926-11
TCMH2329 Realgar 雄黄 TCMH2329
TCMH233 Bufonis venenum 蟾酥 TCMH233
TCMH1678 Indigo naturalis 青黛 TCMH1678
TCMH1814 Sophora subprostrata 山豆根 TCMH1814
TCMH50 Pulvis fumi carbonisatus 白草霜 TCMH50
Reference: CFDA

Targeted Human Proteins by the Ingredients of Prescription

Target ID Gene Symbol Target Name Target Class Uniprot ID
TCMT130 ALOX5 Arachidonate 5-lipoxygenase Oxidoreductase P09917
TCMT136 CA12 Carbonic anhydrase XII Lyase O43570
TCMT138 CA7 Carbonic anhydrase VII Lyase P43166
TCMT142 CA4 Carbonic anhydrase IV Lyase P22748
TCMT162 UGT1A1 UDP-glucuronosyltransferase 1-1 Transferase P22309
TCMT30 PTGS2 Cyclooxygenase-2 Oxidoreductase P35354
TCMT336 IDO1 Indoleamine 2,3-dioxygenase Oxidoreductase P14902
TCMT689 TGM2 Protein-glutamine gamma-glutamyltransferase Transferase P21980


Targeted Pathogenic Microbes by the Ingredients of Prescription

Target ID Target Name
TCMT1229 Enterococcus faecalis
TCMT1255 Human immunodeficiency virus 1
TCMT1353 Plasmodium yoelii
TCMT1438 Plasmodium falciparum
TCMT1439 Mycobacterium smegmatis
TCMT1455 Mycobacterium tuberculosis H37Rv
TCMT1463 Mycobacterium tuberculosis
TCMT1465 Entamoeba histolytica

Gene Ontology Associated to Targeted Human Proteins

GO Term GO Name Enriched Genes Log10 Adjusted P-value


KEGG Pathways Associated to Targeted Human Proteins

KEGG Pathway ID Enriched Genes Log10 Adjusted P-value


Target Exprsssion in Healthy Human Tissues (protein & mRNA level)

Protein expression data was from the "Human Proteome Map" dataset
mRNA expression data was from the "GTEx" dataset



Average Target Expression (Fold Change) in Multiple Disease Conditions

Fold Change with Corresponding Normal Samples
Click each cell within the heatmap to access gene expression of individual patient samples
Data Section
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1. General Information of Prescription  
2. Putative Targets  
3. Activity & References for Filtering Putative Targets  
4. GO & Pathway