Prescription Description
| Prescription ID | TCMFx4542 |
| Pinyin Name | Hou Tong Jie Du Wan |
| Chinese Name | 喉痛解毒丸 |
| English Name | Hou Tong Jie Du Pills |
| Function Description | 喉痹, 乳蛾, æ— å肿毒, å£ç–® |
| Indications | Tonsillitis disorder, Pharyngitis, Aphtha, Tonsillitis |
| Disease ICD-11 Category |
SC93 [Tonsillitis disorder (TM1), 乳蛾 (TM1)
]; CA0Z [Upper respiratory tract disorders, unspecified, 上呼å¸é“疾患，未特指的 ]; DA01.10 [Oral aphthae or aphtha-like ulceration, å£è…”é˜¿å¼—ä»–æºƒç–¡æˆ–é˜¿å¼—ä»–æ ·æºƒç–¡ ]; |
| Human Tissues Associated with Indication | Lung, Liver, Spleen |
| Reference | CFDA |
| Reference Book/link | http://samr.cfda.gov.cn/WS01/CL0001/ |
Prescription Components
| Component ID | Latin Name | Chinese Name | Component Quantity | Barcode |
|---|---|---|---|---|
| TCMH1573 | Bovis calculus | 牛黄 | TCMH1573 | |
| TCMH183 | Dryobalanops aromatica | 冰片 | TCMH183 | GBVK4926-11 |
| TCMH233 | Bufonis venenum | 蟾酥 | TCMH233 | |
| TCMH1678 | Indigo naturalis | é’é»› | TCMH1678 | |
| TCMH50 | Pulvis fumi carbonisatus | 白è‰éœœ | TCMH50 | |
| TCMH2329 | Realgar | 雄黄 | TCMH2329 | |
| TCMH1814 | Sophora subprostrata | å±±è±†æ ¹ | TCMH1814 |
Targeted Human Proteins by the Ingredients of Prescription
| Target ID | Gene Symbol | Target Name | Target Class | Uniprot ID |
|---|---|---|---|---|
| TCMT130 | ALOX5 | Arachidonate 5-lipoxygenase | Oxidoreductase | P09917 |
| TCMT136 | CA12 | Carbonic anhydrase XII | Lyase | O43570 |
| TCMT138 | CA7 | Carbonic anhydrase VII | Lyase | P43166 |
| TCMT142 | CA4 | Carbonic anhydrase IV | Lyase | P22748 |
| TCMT162 | UGT1A1 | UDP-glucuronosyltransferase 1-1 | Transferase | P22309 |
| TCMT30 | PTGS2 | Cyclooxygenase-2 | Oxidoreductase | P35354 |
| TCMT336 | IDO1 | Indoleamine 2,3-dioxygenase | Oxidoreductase | P14902 |
| TCMT689 | TGM2 | Protein-glutamine gamma-glutamyltransferase | Transferase | P21980 |
Targeted Pathogenic Microbes by the Ingredients of Prescription
| Target ID | Target Name |
|---|---|
| TCMT1229 | Enterococcus faecalis |
| TCMT1255 | Human immunodeficiency virus 1 |
| TCMT1353 | Plasmodium yoelii |
| TCMT1438 | Plasmodium falciparum |
| TCMT1439 | Mycobacterium smegmatis |
| TCMT1455 | Mycobacterium tuberculosis H37Rv |
| TCMT1463 | Mycobacterium tuberculosis |
| TCMT1465 | Entamoeba histolytica |
Gene Ontology Associated to Targeted Human Proteins
| GO Term | GO Name | Enriched Genes | Log10 Adjusted P-value |
|---|
KEGG Pathways Associated to Targeted Human Proteins
| KEGG Pathway ID | Enriched Genes | Log10 Adjusted P-value |
|---|
Target Exprsssion in Healthy Human Tissues (protein & mRNA level)
Protein expression data was from the "Human Proteome Map" datasetmRNA expression data was from the "GTEx" dataset
Average Target Expression (Fold Change) in Multiple Disease Conditions
Fold Change with Corresponding Normal SamplesClick each cell within the heatmap to access gene expression of individual patient samples