Description of the Component
Component ID |
TCMH2726 |
Latin Name |
Pterocarpus indicus |
English Name |
Burmacoast padauk |
Chinese Pinyin Name |
Zi Tan |
中文名 |
紫檀 |
TCM Properties |
Warm,Pungent |
TCM Meridians |
Lung,Spleen,Stomach |
Therapeutic Class English |
|
Therapeutic Class Chinese |
|
Functions |
|
Toxicity |
NA |
Geo-authentic habitats (道地产区) |
NA |
Reference |
Chinese Pharmacopoeia (2015) |
Barcode ID |
ITSAA3130-14 |
Barcode Source |
BOLDSYSTEMS |
Targeted Human Proteins by the Ingredient of Component
| Target ID | Gene Symbol | Target Name | Target Class | Uniprot ID |
|---|---|---|---|---|
| TCMT1 | EHMT2 | Histone-lysine N-methyltransferase, H3 lysine-9 specific 3 | Transferase | Q96KQ7 |
| TCMT11 | HIF1A | Hypoxia-inducible factor 1 alpha | Transcription factor | Q16665 |
| TCMT125 | GBA | Beta-glucocerebrosidase | Hydrolase | P04062 |
| TCMT130 | ALOX5 | Arachidonate 5-lipoxygenase | Oxidoreductase | P09917 |
| TCMT131 | ACHE | Acetylcholinesterase | Hydrolase | P22303 |
| TCMT133 | CA1 | Carbonic anhydrase I | Lyase | P00915 |
| TCMT134 | CA2 | Carbonic anhydrase II | Lyase | P00918 |
| TCMT156 | CYP19A1 | Cytochrome P450 19A1 | Oxidoreductase | P11511 |
| TCMT17 | POLB | DNA polymerase beta | Transferase | P06746 |
| TCMT18 | GAA | Lysosomal alpha-glucosidase | Hydrolase | P10253 |
| TCMT187 | AR | Androgen Receptor | Nuclear receptor | P10275 |
| TCMT2 | MAPT | Microtubule-associated protein tau | Unclassified | P10636 |
| TCMT212 | SRC | Tyrosine-protein kinase SRC | Kinase | P12931 |
| TCMT223 | AKR1B1 | Aldose reductase | Oxidoreductase | P15121 |
| TCMT236 | ESR2 | Estrogen receptor beta | Nuclear receptor | Q92731 |
| TCMT237 | SLC5A1 | Sodium/glucose cotransporter 1 | Transporter | P13866 |
| TCMT238 | SLC5A2 | Sodium/glucose cotransporter 2 | Transporter | P31639 |
| TCMT239 | PIM1 | Serine/threonine-protein kinase PIM1 | Kinase | P11309 |
| TCMT240 | AMY1A | Salivary alpha-amylase | Unclassified | P04745 |
| TCMT248 | CXCL8 | Interleukin-8 | Unclassified | P10145 |
| TCMT261 | DAPK1 | Death-associated protein kinase 1 | Kinase | P53355 |
| TCMT276 | SLCO2B1 | Solute carrier organic anion transporter family member 2B1 | Transporter | O94956 |
| TCMT277 | SLCO1B3 | Solute carrier organic anion transporter family member 1B3 | Transporter | Q9NPD5 |
| TCMT278 | SLCO1B1 | Solute carrier organic anion transporter family member 1B1 | Transporter | Q9Y6L6 |
| TCMT289 | TBXAS1 | Thromboxane-A synthase | Isomerase | P24557 |
| TCMT295 | MMP1 | Matrix metalloproteinase-1 | Hydrolase | P03956 |
| TCMT3 | ALOX15 | Arachidonate 15-lipoxygenase | Oxidoreductase | P16050 |
| TCMT306 | MMP2 | Matrix metalloproteinase-2 | Hydrolase | P08253 |
| TCMT31 | CYP2C19 | Cytochrome P450 2C19 | Oxidoreductase | P33261 |
| TCMT320 | MMP3 | Matrix metalloproteinase 3 | Hydrolase | P08254 |
| TCMT321 | MMP9 | Matrix metalloproteinase 9 | Hydrolase | P14780 |
| TCMT33 | CYP3A4 | Cytochrome P450 3A4 | Oxidoreductase | P08684 |
| TCMT344 | AOX1 | Aldehyde oxidase | Oxidoreductase | Q06278 |
| TCMT359 | FYN | Tyrosine-protein kinase FYN | Kinase | P06241 |
| TCMT41 | IDH1 | Isocitrate dehydrogenase [NADP] cytoplasmic | Oxidoreductase | O75874 |
| TCMT423 | EGFR | Epidermal growth factor receptor erbB1 | Kinase | P00533 |
| TCMT479 | AKT1 | Serine/threonine-protein kinase AKT | Kinase | P31749 |
| TCMT558 | TOP2A | DNA topoisomerase II alpha | Isomerase | P11388 |
| TCMT567 | DNMT1 | DNA (cytosine-5)-methyltransferase 1 | Transferase | P26358 |
| TCMT591 | ESRRA | Estrogen-related receptor alpha | Nuclear receptor | P11474 |
| TCMT6 | NFKB1 | Nuclear factor NF-kappa-B p105 subunit | Transcription factor | P19838 |
| TCMT613 | NR3C1 | Glucocorticoid receptor | Nuclear receptor | P04150 |
| TCMT63 | PPARA | Peroxisome proliferator-activated receptor alpha | Nuclear receptor | Q07869 |
| TCMT65 | HSD17B1 | Estradiol 17-beta-dehydrogenase 1 | Oxidoreductase | P14061 |
| TCMT66 | HSD17B2 | Estradiol 17-beta-dehydrogenase 2 | Oxidoreductase | P37059 |
| TCMT67 | PPARG | Peroxisome proliferator-activated receptor gamma | Nuclear receptor | P37231 |
| TCMT714 | ODC1 | Ornithine decarboxylase | Lyase | P11926 |
| TCMT8 | KDM4E | Lysine-specific demethylase 4D-like | Oxidoreductase | B2RXH2 |
| TCMT80 | MAPK1 | MAP kinase ERK2 | Kinase | P28482 |
| TCMT82 | ESR1 | Estrogen receptor alpha | Nuclear receptor | P03372 |
| TCMT87 | CYP2C9 | Cytochrome P450 2C9 | Oxidoreductase | P11712 |
| TCMT910 | ESRRB | Estrogen-related receptor beta | Nuclear receptor | O95718 |
| TCMT99 | SHBG | Testis-specific androgen-binding protein | Unclassified | P04278 |
Targeted Pathogenic Microbes by the Ingredient of Component
| Target ID | Target Name |
|---|---|
| TCMT1090 | Human immunodeficiency virus type 1 integrase |
| TCMT1092 | Fatty acid synthase |
| TCMT1099 | Neuraminidase |
| TCMT1104 | Sortase |
| TCMT1170 | Enterobacter cloacae |
| TCMT1176 | Streptococcus pneumoniae |
| TCMT1213 | Neisseria gonorrhoeae |
| TCMT1218 | Staphylococcus aureus |
| TCMT1229 | Enterococcus faecalis |
| TCMT1246 | Escherichia coli |
| TCMT1251 | Candida albicans |
| TCMT1438 | Plasmodium falciparum |
| TCMT1454 | Bacillus subtilis |
| TCMT1458 | Filobasidiella neoformans |
| TCMT1462 | Streptococcus mutans |
Ingredient Structrues
Ingredient ID: TCMC995
Formula: C35H60O6
Ingredient ID: TCMC984
Formula: C21H20O9
Ingredient ID: TCMC845
Formula: C15H24O
Ingredient ID: TCMC699
Formula: C16H16O4
Ingredient ID: TCMC407
Formula: C15H10O6
Ingredient ID: TCMC394
Formula: C2H5NO3
Ingredient ID: TCMC274
Formula: C6H14O
Ingredient ID: TCMC2564
Formula: C16H16O3
Ingredient ID: TCMC228
Formula: C6H14O2
Ingredient ID: TCMC1963
Formula: C17H14O5
Ingredient ID: TCMC1530
Formula: C6H6O3
Ingredient ID: TCMC1236
Formula: C15H10O5
Properties
| Ingredient ID | Formulae | Name | MW | AlogP | MlogP | XlogP | # HBA | # HBD | PSA | # Rotatable Bond | # Ring | # Heacy Atom | Lipinski RO5 Violation |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| TCMC228 | C6H14O2 | 1,1-Diethoxyethane | 118.1 | 0.8705 | 1.9 | 1.273 | 2 | 0 | 18.46 | 7 | 0 | 8 | 0 |
| TCMC274 | C6H14O | 1-Hexanol | 102.1 | -1.5494 | 2.01 | 1.989 | 1 | 1 | 20.23 | 6 | 0 | 7 | 0 |
| TCMC394 | C2H5NO3 | 2-Nitroethanol | 91.03 | -0.0012 | 1.24 | -0.527 | 1 | 1 | 63.37 | 4 | 0 | 6 | 0 |
| TCMC407 | C15H10O6 | 3-(2,4-Dihydroxyphenyl)-5,7-Dihydroxychromen-4-One | 286.05 | -2.5079 | 2.45 | 0.549 | 1 | 4 | 107.22 | 5 | 3 | 21 | 0 |
| TCMC699 | C16H16O4 | Angolensin | 272.1 | -0.9414 | 2.78 | 2.755 | 1 | 2 | 66.76 | 8 | 2 | 20 | 0 |
| TCMC845 | C15H24O | Butylated Hydroxytoluene | 220.18 | 3.2941 | 3 | 5.957 | 0 | 1 | 20.23 | 10 | 1 | 16 | 1 |
| TCMC984 | C21H20O9 | Daidzin | 416.11 | -3.3342 | 2.78 | 1.367 | 6 | 5 | 145.91 | 9 | 4 | 30 | 0 |
| TCMC995 | C35H60O6 | Daucosterol | 576.44 | -0.4469 | 4.65 | 10.487 | 6 | 4 | 99.38 | 19 | 5 | 41 | 1 |
| TCMC1236 | C15H10O5 | Genistein | 270.05 | -2.0476 | 2.56 | 1.512 | 1 | 3 | 86.99 | 4 | 3 | 20 | 0 |
| TCMC1530 | C6H6O3 | Maltol | 126.03 | -0.6804 | 1.79 | 0.907 | 3 | 1 | 46.53 | 2 | 1 | 9 | 0 |
| TCMC1963 | C17H14O5 | Pterocarpin | 298.08 | -1.0076 | 2.78 | 2.316 | 0 | 0 | 46.15 | 2 | 5 | 22 | 0 |
| TCMC2564 | C16H16O3 | (Z)-4-(3,5-Dimethoxystyryl)Phenol | 256.11 | -0.0961 | 2.89 | 4.474 | 0 | 1 | 38.69 | 7 | 2 | 19 | 0 |
Download Data
All data can be downloaded by:→ Selecting data type in the below download table
→ Then click the download button.
