TCM-ID Component

Description of the Component

Component ID	TCMH2128
Latin Name	Rhizoma bolbostemmae
English Name	Paniculate bolbostemma
Chinese Pinyin Name	Tu Bei Mu
中文名	åœŸè´æ¯
TCM Properties	Minor cold,Pungent,Sweet,Bitter
TCM Meridians	Lung,Heart
Therapeutic Class English	For desolving phlegm, stopping cougth, and soothing breathing
Therapeutic Class Chinese	åŒ–ç—°æ¢å’³å¹³å–˜
Functions	dissolve lumps, cause subsidence of swelling, and counteract toxicity
Toxicity	NA
Geo-authentic habitats (道地产区)	NA
Reference	Chinese Pharmacopoeia (2015)
Barcode ID
Barcode Source

TCM Prescriptions with the Component

Prescription ID	Prescription English Name	Prescription Chinese Name
TCMFx2851	Hua Gan Decoction	åŒ–è‚ç…Ž
TCMFx1911	Liver Desolving Fries	åŒ–è‚ç…Ž
TCMFx4511	Pi Fu Bing Xue Du Pills	çš®è‚¤ç—…è¡€æ¯’ä¸¸
TCMFx656	Ru Zeng Ning Capsule	ä¹³å¢žå®èƒ¶å›Š
TCMFx2150	Tumor Removing Decoction	æ¶ˆç˜¿æ±¤

Targeted Human Proteins by the Ingredient of Component

Target ID	Gene Symbol	Target Name	Target Class	Uniprot ID
TCMT1	EHMT2	Histone-lysine N-methyltransferase, H3 lysine-9 specific 3	Transferase	Q96KQ7
TCMT130	ALOX5	Arachidonate 5-lipoxygenase	Oxidoreductase	P09917
TCMT295	MMP1	Matrix metalloproteinase-1	Hydrolase	P03956
TCMT306	MMP2	Matrix metalloproteinase-2	Hydrolase	P08253
TCMT320	MMP3	Matrix metalloproteinase 3	Hydrolase	P08254
TCMT321	MMP9	Matrix metalloproteinase 9	Hydrolase	P14780
TCMT8	KDM4E	Lysine-specific demethylase 4D-like	Oxidoreductase	B2RXH2

Targeted Pathogenic Microbes by the Ingredient of Component

Target ID	Target Name

Ingredient Structrues

Ingredient ID: TCMC6309
Formula: C29H50O

Common Name	24-Ethylcholesterol,Beta-Sitosterol
IUPAC Name	(8S,9S,10R,13R,14S,17R)-17-[(2R,5S)-5-ethyl-6-methylheptan-2-yl]-10,13-dimethyl-2,3,4,7,8,9,11,12,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-3-ol
Canonical SMILES	CC[C@H](C(C)C)CC[C@H]([C@H]1CC[C@@H]2[C@]1(C)CC[C@H]1[C@H]2CC=C2[C@]1(C)CCC(C2)O)C
Standard InCHI	InChI=1S/C29H50O/c1-7-21(19(2)3)9-8-20(4)25-12-13-26-24-11-10-22-18-23(30)14-16-28(22,5)27(24)15-17-29(25,26)6/h10,19-21,23-27,30H,7-9,11-18H2,1-6H3/t20-,21+,23?,24+,25-,26+,27+,28+,29-/m1/s1
Standard InCHIKey	KZJWDPNRJALLNS-VWNOLRCJSA-N
External Identifiers	ChEMBL [N/A]; PubChem [16057789];
Reference of Component-Ingredient Pair	US7090863

Occurrence of the ingredient across TCM components

Component ID	Latin Name	Pinyin Name	Chinese Name
TCMH31	Morinda officinalis	Ba Ji Tian	å·´æˆŸå¤©
TCMH2128	Rhizoma bolbostemmae	Tu Bei Mu	åœŸè´æ¯

Ingredient ID: TCMC5527
Formula: C12H17NO4

Common Name	Methyl 4-[2-Formyl-5-(Methoxymethyl)Pyrrol-1-Yl]Butanoate
IUPAC Name	methyl 4-[2-formyl-5-(methoxymethyl)pyrrol-1-yl]butanoate
Canonical SMILES	COCc1ccc(n1CCCC(=O)OC)C=O
Standard InCHI	InChI=1S/C12H17NO4/c1-16-9-11-6-5-10(8-14)13(11)7-3-4-12(15)17-2/h5-6,8H,3-4,7,9H2,1-2H3
Standard InCHIKey	XLRBRYWTMDPGLK-UHFFFAOYSA-N
External Identifiers	ChEMBL [CHEMBL352400]; PubChem [10911621];
Reference of Component-Ingredient Pair	N/A

Occurrence of the ingredient across TCM components

Component ID	Latin Name	Pinyin Name	Chinese Name
TCMH2128	Rhizoma bolbostemmae	Tu Bei Mu	åœŸè´æ¯

Ingredient ID: TCMC4321
Formula: C32H44O8

Common Name	Cucurbitacin E
IUPAC Name	[(E,6R)-6-[(8S,9R,10R,13R,14S,16R,17R)-2,16-dihydroxy-4,4,9,13,14-pentamethyl-3,11-dioxo-8,10,12,15,16,17-hexahydro-7H-cyclopenta[a]phenanthren-17-yl]-6-hydroxy-2-methyl-5-oxohept-3-en-2-yl] acetate
Canonical SMILES	CC(=O)OC(/C=C/C(=O)[C@@]([C@H]1[C@H](O)C[C@@]2([C@]1(C)CC(=O)[C@@]1([C@H]2CC=C2[C@H]1C=C(O)C(=O)C2(C)C)C)C)(O)C)(C)C
Standard InCHI	InChI=1S/C32H44O8/c1-17(33)40-27(2,3)13-12-23(36)32(9,39)25-21(35)15-29(6)22-11-10-18-19(14-20(34)26(38)28(18,4)5)31(22,8)24(37)16-30(25,29)7/h10,12-14,19,21-22,25,34-35,39H,11,15-16H2,1-9H3/b13-12+/t19-,21-,22+,25+,29+,30-,31+,32+/m1/s1
Standard InCHIKey	NDYMQXYDSVBNLL-MUYMLXPFSA-N
External Identifiers	ChEMBL [CHEMBL455056]; PubChem [5281319];
Reference of Component-Ingredient Pair	22842972

Occurrence of the ingredient across TCM components

Component ID	Latin Name	Pinyin Name	Chinese Name
TCMH2128	Rhizoma bolbostemmae	Tu Bei Mu	åœŸè´æ¯

Ingredient ID: TCMC3815
Formula: C4H6N4O3

Common Name	(R)-Allantoin,Allantoin
IUPAC Name	[(4R)-2,5-dioxoimidazolidin-4-yl]urea
Canonical SMILES	NC(=O)N[C@@H]1NC(=O)NC1=O
Standard InCHI	InChI=1S/C4H6N4O3/c5-3(10)6-1-2(9)8-4(11)7-1/h1H,(H3,5,6,10)(H2,7,8,9,11)/t1-/m1/s1
Standard InCHIKey	POJWUDADGALRAB-PVQJCKRUSA-N
External Identifiers	ChEMBL [N/A]; PubChem [439713];
Reference of Component-Ingredient Pair	17428786

Occurrence of the ingredient across TCM components

Component ID	Latin Name	Pinyin Name	Chinese Name
TCMH677	Pueraria lobata	Ge Gen	è‘›æ ¹
TCMH1397	Aristolochia debilis	Ma Dou Ling	é©¬å…œé“ƒ
TCMH1845	Dioscorea batatas	Shan Yao	å±±è¯
TCMH2128	Rhizoma bolbostemmae	Tu Bei Mu	åœŸè´æ¯

Ingredient ID: TCMC3678
Formula: C12H22O11

Common Name	4-O-A-D-Glucopyranosyl-D-Glucose
IUPAC Name	(2R,3R,4R,5R)-2,3,5,6-tetrahydroxy-4-[(2R,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxyhexanal
Canonical SMILES	OC[C@H]([C@H]([C@@H]([C@H](C=O)O)O)O[C@H]1O[C@H](CO)[C@H]([C@@H]([C@H]1O)O)O)O
Standard InCHI	InChI=1S/C12H22O11/c13-1-4(16)7(18)11(5(17)2-14)23-12-10(21)9(20)8(19)6(3-15)22-12/h1,4-12,14-21H,2-3H2/t4-,5+,6+,7+,8+,9-,10+,11+,12+/m0/s1
Standard InCHIKey	DKXNBNKWCZZMJT-WUJBLJFYSA-N
External Identifiers	ChEMBL [N/A]; PubChem [181526];
Reference of Component-Ingredient Pair	22237946

Occurrence of the ingredient across TCM components

Component ID	Latin Name	Pinyin Name	Chinese Name
TCMH2128	Rhizoma bolbostemmae	Tu Bei Mu	åœŸè´æ¯

Ingredient ID: TCMC3399
Formula: C6H12O6

Common Name	D-Glucose,Glucose
IUPAC Name	(2R,3S,4R,5R)-2,3,4,5,6-pentahydroxyhexanal
Canonical SMILES	OC[C@H]([C@H]([C@@H]([C@H](C=O)O)O)O)O
Standard InCHI	InChI=1S/C6H12O6/c7-1-3(9)5(11)6(12)4(10)2-8/h1,3-6,8-12H,2H2/t3-,4+,5+,6+/m0/s1
Standard InCHIKey	GZCGUPFRVQAUEE-SLPGGIOYSA-N
External Identifiers	ChEMBL [N/A]; PubChem [107526];
Reference of Component-Ingredient Pair	18071748

Occurrence of the ingredient across TCM components

Component ID	Latin Name	Pinyin Name	Chinese Name
TCMH1329	Arillus longan	Long Yan Rou	é¾™çœ¼è‚‰
TCMH451	Rehmannia glutinosa	Di Huang	åœ°é»„
TCMH2084	Asparagus cochinchinensis	Tian Dong	å¤©å†¬
TCMH2128	Rhizoma bolbostemmae	Tu Bei Mu	åœŸè´æ¯
TCMH2102	Concretio silicea bambusae	Tian Zhu Huang	å¤©ç«ºé»„

Ingredient ID: TCMC3089
Formula: C6H7NO

Common Name	2-Acetyl-1H-Pyrrole
IUPAC Name	1-(1H-pyrrol-2-yl)ethanone
Canonical SMILES	CC(=O)c1ccc[nH]1
Standard InCHI	InChI=1S/C6H7NO/c1-5(8)6-3-2-4-7-6/h2-4,7H,1H3
Standard InCHIKey	IGJQUJNPMOYEJY-UHFFFAOYSA-N
External Identifiers	ChEMBL [CHEMBL1414126]; PubChem [14079];
Reference of Component-Ingredient Pair	22871255

Occurrence of the ingredient across TCM components

Component ID	Latin Name	Pinyin Name	Chinese Name
TCMH2128	Rhizoma bolbostemmae	Tu Bei Mu	åœŸè´æ¯

Ingredient ID: TCMC3069
Formula: C31H64

Common Name	Hentriacontane
IUPAC Name	hentriacontane
Canonical SMILES	CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
Standard InCHI	InChI=1S/C31H64/c1-3-5-7-9-11-13-15-17-19-21-23-25-27-29-31-30-28-26-24-22-20-18-16-14-12-10-8-6-4-2/h3-31H2,1-2H3
Standard InCHIKey	IUJAMGNYPWYUPM-UHFFFAOYSA-N
External Identifiers	ChEMBL [CHEMBL257490]; PubChem [12410];
Reference of Component-Ingredient Pair	22359371

Occurrence of the ingredient across TCM components

Component ID	Latin Name	Pinyin Name	Chinese Name
TCMH241	Plantago asiatica	Che Qian Zi	è½¦å‰å
TCMH1368	Apocyni veneti folium	Luo Bu Ma Ye	ç½—å¸ƒéº»å¶
TCMH1219	Semen armeniacae amarum	Ku Xing Ren	è‹¦æä»
TCMH2128	Rhizoma bolbostemmae	Tu Bei Mu	åœŸè´æ¯
TCMH2507	Epimedium brevicornum	Yin Yang Huo	æ·«ç¾Šè—¿

Ingredient ID: TCMC3068
Formula: C29H60

Common Name	Nonacosane
IUPAC Name	nonacosane
Canonical SMILES	CCCCCCCCCCCCCCCCCCCCCCCCCCCCC
Standard InCHI	InChI=1S/C29H60/c1-3-5-7-9-11-13-15-17-19-21-23-25-27-29-28-26-24-22-20-18-16-14-12-10-8-6-4-2/h3-29H2,1-2H3
Standard InCHIKey	IGGUPRCHHJZPBS-UHFFFAOYSA-N
External Identifiers	ChEMBL [CHEMBL428955]; PubChem [12409];
Reference of Component-Ingredient Pair	22292044

Occurrence of the ingredient across TCM components

Component ID	Latin Name	Pinyin Name	Chinese Name
TCMH389	Gleditsiae sinensis fructus	Da Zao Jiao	å¤§çš‚è§’
TCMH524	Eucommia ulmoides	Du Zhong	æœä»²
TCMH865	Carthamus tinctorius	Hong Hua	çº¢èŠ±
TCMH1368	Apocyni veneti folium	Luo Bu Ma Ye	ç½—å¸ƒéº»å¶
TCMH877	Radix ginseng rubra	Hong Shen	çº¢å‚
TCMH1813	Asarum sagittarioides	Shan Ci Gu	å±±æ…ˆè‡
TCMH1721	Panax ginseng	Ren Shen	äººå‚
TCMH925	Exocarpium citri grandis	Hua Ju Hong	åŒ–æ©˜çº¢
TCMH1219	Semen armeniacae amarum	Ku Xing Ren	è‹¦æä»
TCMH2128	Rhizoma bolbostemmae	Tu Bei Mu	åœŸè´æ¯
TCMH2641	Gardenia jasminoides	Zhi Zi	æ €å
TCMH2252	Agrimonia pilosa var. japonica	Xian He Cao	ä»™é¹¤è‰
TCMH2693	Fructus gleditsiae abnormalis	Zhu Ya Zao	çŒªç‰™çš‚

Ingredient ID: TCMC2886
Formula: C12H22O11

Common Name	Sucrose
IUPAC Name	(2R,3R,4S,5S,6R)-2-[(2S,3S,4S,5R)-3,4-dihydroxy-2,5-bis(hydroxymethyl)oxolan-2-yl]oxy-6-(hydroxymethyl)oxane-3,4,5-triol
Canonical SMILES	OC[C@H]1O[C@@]([C@H]([C@@H]1O)O)(CO)O[C@H]1O[C@H](CO)[C@H]([C@@H]([C@H]1O)O)O
Standard InCHI	InChI=1S/C12H22O11/c13-1-4-6(16)8(18)9(19)11(21-4)23-12(3-15)10(20)7(17)5(2-14)22-12/h4-11,13-20H,1-3H2/t4-,5-,6-,7-,8+,9-,10+,11-,12+/m1/s1
Standard InCHIKey	CZMRCDWAGMRECN-UGDNZRGBSA-N
External Identifiers	ChEMBL [CHEMBL253582]; PubChem [5988];
Reference of Component-Ingredient Pair	29968805

Occurrence of the ingredient across TCM components

Component ID	Latin Name	Pinyin Name	Chinese Name
TCMH381	Isatis indigotica	Da Qing Ye	å¤§é’å¶
TCMH206	Fructus xanthii sibirici	Cang Er Zi	è‹è€³å
TCMH240	Plantago depressa	Che Qian Cao	è½¦å‰è‰
TCMH90	Imperata cylindrica	Bai Mao Gen	ç™½èŒ…æ ¹
TCMH241	Plantago asiatica	Che Qian Zi	è½¦å‰å
TCMH182	Areca catechu	Bing Lang	æ§Ÿæ¦”
TCMH127	Isatis indigotica	Ban Lan Gen	æ¿è“æ ¹
TCMH562	Saposhnikovia divaricata	Fang Feng	é˜²é£Ž
TCMH327	Eleutherococcus senticosus	Ci Wu Jia	åˆºäº”åŠ
TCMH273	Fritillaria cirrhosa	Chuan Bei Mu	å·è´æ¯
TCMH45	Lablab purpureus	Bai Bian Dou	ç™½æ‰è±†
TCMH388	Ziziphus jujuba	Da Zao	å¤§æž£
TCMH981	Astragalus membranaceus	Huang Qi	é»„èŠª
TCMH986	Scutellaria baicalensis	Huang Qin	é»„èŠ©
TCMH1329	Arillus longan	Long Yan Rou	é¾™çœ¼è‚‰
TCMH1343	Aloe vera	Lu Hui	èŠ¦èŸ
TCMH1396	Portulaca oleracea	Ma Chi Xian	é©¬é½¿è‹‹
TCMH1953	Pyrrosia lingua	Shi Wei	çŸ³éŸ¦
TCMH1665	Notopterygium incisum	Qiang Huo	ç¾Œæ´»
TCMH1848	Crataegus pinnatifida	Shan Zha	å±±æ¥‚
TCMH1862	Cornus officinalis	Shan Zhu Yu	å±±èŒ±è¸
TCMH1721	Panax ginseng	Ren Shen	äººå‚
TCMH1798	Morus alba	Sang Zhi	æ¡‘æž
TCMH451	Rehmannia glutinosa	Di Huang	åœ°é»„
TCMH2084	Asparagus cochinchinensis	Tian Dong	å¤©å†¬
TCMH2128	Rhizoma bolbostemmae	Tu Bei Mu	åœŸè´æ¯
TCMH2090	Gastrodia elata	Tian Ma	å¤©éº»
TCMH2684	Ardisia crenata	Zhu Sha Gen	æœ±ç ‚æ ¹
TCMH2241	Panax quinquefolium	Xi Yang Shen	è¥¿æ´‹å‚

Ingredient ID: TCMC1530
Formula: C6H6O3

Common Name	Maltol
IUPAC Name	3-hydroxy-2-methylpyran-4-one
Canonical SMILES	O=c1ccoc(c1O)C
Standard InCHI	InChI=1S/C6H6O3/c1-4-6(8)5(7)2-3-9-4/h2-3,8H,1H3
Standard InCHIKey	XPCTZQVDEJYUGT-UHFFFAOYSA-N
External Identifiers	ChEMBL [CHEMBL31422]; PubChem [8369];
Reference of Component-Ingredient Pair	22542289

Occurrence of the ingredient across TCM components

Component ID	Latin Name	Pinyin Name	Chinese Name
TCMH260	Semen phaseoli	Chi Xiao Dou	èµ¤å°è±†
TCMH422	Angelica sinensis	Dang Gui Gan Jin Gao	å½“å½’å¹²æµ¸è†
TCMH1839	Panax ginseng	Shan Shen	å±±å‚
TCMH255	Vigna angularis	Chi Dou	èµ¤è±†
TCMH494	Cordyceps sinensis	Dong Chong Xia Cao	å†¬è™«å¤è‰
TCMH1428	Ophiopogon japonicus	Mai Men Dong	éº¦é—¨å†¬
TCMH1777	Panax notoginseng	San Qi Ye Jing	ä¸‰ä¸ƒå¶èŒŽ
TCMH421	Angelica sinensis	Dang Gui	å½“å½’
TCMH1770	Panax notoginseng	San Qi Gan Jin Gao	ä¸‰ä¸ƒå¹²æµ¸è†
TCMH1771	Panax notoginseng	San Qi Gao Fen	ä¸‰ä¸ƒè†ç²‰
TCMH1772	Panax notoginseng	San Qi Hua	ä¸‰ä¸ƒèŠ±
TCMH1774	Panax notoginseng	San Qi Jing Ye	ä¸‰ä¸ƒèŒŽå¶
TCMH1776	Panax notoginseng	San Qi Ye	ä¸‰ä¸ƒå¶
TCMH1721	Panax ginseng	Ren Shen	äººå‚
TCMH1728	Panax ginseng	Ren Shen Ye	äººå‚å¶
TCMH1423	Ophiopogon japonicus	Mai Dong	éº¦å†¬
TCMH1424	Ophiopogon japonicus	Mai Dong Men	éº¦å†¬é—¨
TCMH1425	Ophiopogon japonicus	Mai Dong Rou	éº¦å†¬è‚‰
TCMH2128	Rhizoma bolbostemmae	Tu Bei Mu	åœŸè´æ¯
TCMH2726	Pterocarpus indicus	Zi Tan	ç´«æª€

Properties

Ingredient ID	Formulae	Name	MW	AlogP	MlogP	XlogP	# HBA	# HBD	PSA	# Rotatable Bond	# Ring	# Heacy Atom	Lipinski RO5 Violation
TCMC1530	C6H6O3	Maltol	126.03	-0.6804	1.79	0.907	3	1	46.53	2	1	9	0
TCMC2886	C12H22O11	Sucrose	342.1162115	-4.3105	1.57	-3.277	11	8	189.53	5	2	23	2
TCMC3068	C29H60	Nonacosane	408.4695019	-7.6734	4.65	16.841	0	0	0	26	0	29	2
TCMC3069	C31H64	Hentriacontane	436.500802	-8.2494	4.87	17.979	0	0	0	28	0	31	2
TCMC3089	C6H7NO	2-Acetyl-1H-Pyrrole	109.0527638	-0.6743	1.9	0.712	2	1	32.86	1	1	8	0
TCMC3399	C6H12O6	D-Glucose,Glucose	180.0633881	-2.7906	1.46	-3.325	6	5	118.22	5	0	12	0
TCMC3678	C12H22O11	4-O-A-D-Glucopyranosyl-D-Glucose	342.1162115	-4.5375	1.57	-4.433	11	8	197.37	8	1	23	2
TCMC3815	C4H6N4O3	(R)-Allantoin,Allantoin	158.0439901	-1.2413	1.13	-1.169	7	4	113.32	2	1	11	0
TCMC4321	C32H44O8	Cucurbitacin E	556.3036184	1.1668	4.1	3.404	8	3	138.2	6	4	40	0
TCMC5527	C12H17NO4	Methyl 4-[2-Formyl-5-(Methoxymethyl)Pyrrol-1-Yl]Butanoate	239.115758	-0.4498	2.23	1.203	5	0	57.53	8	1	17	0
TCMC6309	C29H50O	24-Ethylcholesterol,Beta-Sitosterol	414.3861662	1.3	4.54	11.595	1	1	20.23	6	4	30	1

Download Data

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Data Section	Select to Download
1. General Information of the Component
2. TCM Prescriptions with the Component
3. Putative Targets
4. Activity & References for Filtering Putative Targets
5. Ingredient Data & Chemical Structure Information (Properties, InChI, InChIkey, SMILES, etc.)

Component: Rhizoma bolbostemmae åœŸè´æ¯

Description of the Component

Component ID

Latin Name

English Name

Chinese Pinyin Name

中文名

TCM Properties

TCM Meridians

Therapeutic Class English

Therapeutic Class Chinese

Functions

Toxicity

Geo-authentic habitats (道地产区)

Reference

Barcode ID

Barcode Source

TCM Prescriptions with the Component

Targeted Human Proteins by the Ingredient of Component

Targeted Pathogenic Microbes by the Ingredient of Component

Ingredient Structrues

Ingredient ID: TCMC6309

Occurrence of the ingredient across TCM components

Ingredient ID: TCMC5527

Occurrence of the ingredient across TCM components

Ingredient ID: TCMC4321

Occurrence of the ingredient across TCM components

Ingredient ID: TCMC3815

Occurrence of the ingredient across TCM components

Ingredient ID: TCMC3678

Occurrence of the ingredient across TCM components

Ingredient ID: TCMC3399

Occurrence of the ingredient across TCM components

Ingredient ID: TCMC3089

Occurrence of the ingredient across TCM components

Ingredient ID: TCMC3069

Occurrence of the ingredient across TCM components

Ingredient ID: TCMC3068

Occurrence of the ingredient across TCM components

Ingredient ID: TCMC2886

Occurrence of the ingredient across TCM components

Ingredient ID: TCMC1530

Occurrence of the ingredient across TCM components

Properties

Download Data

Component: Rhizoma bolbostemmae åœŸè´æ¯