TCM-ID Component

Description of the Component

Component ID	TCMH2128
Latin Name	Rhizoma bolbostemmae
English Name	Paniculate bolbostemma
Chinese Pinyin Name	Tu Bei Mu
中文名	土贝母
TCM Properties	Minor cold,Pungent,Sweet,Bitter
TCM Meridians	Lung,Heart
Therapeutic Class English	For desolving phlegm, stopping cougth, and soothing breathing
Therapeutic Class Chinese	化痰止咳平喘
Functions	dissolve lumps, cause subsidence of swelling, and counteract toxicity
Toxicity	NA
Geo-authentic habitats (道地产区)	NA
Reference	Chinese Pharmacopoeia (2015)
Barcode ID
Barcode Source

TCM Prescriptions with the Component

Prescription ID	Prescription English Name	Prescription Chinese Name
TCMFx2851	Hua Gan Decoction	化肝煎
TCMFx1911	Liver Desolving Fries	化肝煎
TCMFx4511	Pi Fu Bing Xue Du Pills	皮肤病血毒丸
TCMFx656	Ru Zeng Ning Capsule	乳增宁胶囊
TCMFx2150	Tumor Removing Decoction	消瘿汤

Targeted Human Proteins by the Ingredient of Component

Target ID	Gene Symbol	Target Name	Target Class	Uniprot ID
TCMT1	EHMT2	Histone-lysine N-methyltransferase, H3 lysine-9 specific 3	Transferase	Q96KQ7
TCMT130	ALOX5	Arachidonate 5-lipoxygenase	Oxidoreductase	P09917
TCMT295	MMP1	Matrix metalloproteinase-1	Hydrolase	P03956
TCMT306	MMP2	Matrix metalloproteinase-2	Hydrolase	P08253
TCMT320	MMP3	Matrix metalloproteinase 3	Hydrolase	P08254
TCMT321	MMP9	Matrix metalloproteinase 9	Hydrolase	P14780
TCMT8	KDM4E	Lysine-specific demethylase 4D-like	Oxidoreductase	B2RXH2

Targeted Pathogenic Microbes by the Ingredient of Component

Target ID	Target Name

Ingredient Structrues

Ingredient ID: TCMC6309
Formula: C29H50O

Common Name	24-Ethylcholesterol,Beta-Sitosterol
IUPAC Name	(8S,9S,10R,13R,14S,17R)-17-[(2R,5S)-5-ethyl-6-methylheptan-2-yl]-10,13-dimethyl-2,3,4,7,8,9,11,12,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-3-ol
Canonical SMILES	CC[C@H](C(C)C)CC[C@H]([C@H]1CC[C@@H]2[C@]1(C)CC[C@H]1[C@H]2CC=C2[C@]1(C)CCC(C2)O)C
Standard InCHI	InChI=1S/C29H50O/c1-7-21(19(2)3)9-8-20(4)25-12-13-26-24-11-10-22-18-23(30)14-16-28(22,5)27(24)15-17-29(25,26)6/h10,19-21,23-27,30H,7-9,11-18H2,1-6H3/t20-,21+,23?,24+,25-,26+,27+,28+,29-/m1/s1
Standard InCHIKey	KZJWDPNRJALLNS-VWNOLRCJSA-N
External Identifiers	ChEMBL [N/A]; PubChem [16057789];
Reference of Component-Ingredient Pair	US7090863

Occurrence of the ingredient across TCM components

Component ID	Latin Name	Pinyin Name	Chinese Name
TCMH31	Morinda officinalis	Ba Ji Tian	巴戟天
TCMH2128	Rhizoma bolbostemmae	Tu Bei Mu	土贝母

Ingredient ID: TCMC5527
Formula: C12H17NO4

Common Name	Methyl 4-[2-Formyl-5-(Methoxymethyl)Pyrrol-1-Yl]Butanoate
IUPAC Name	methyl 4-[2-formyl-5-(methoxymethyl)pyrrol-1-yl]butanoate
Canonical SMILES	COCc1ccc(n1CCCC(=O)OC)C=O
Standard InCHI	InChI=1S/C12H17NO4/c1-16-9-11-6-5-10(8-14)13(11)7-3-4-12(15)17-2/h5-6,8H,3-4,7,9H2,1-2H3
Standard InCHIKey	XLRBRYWTMDPGLK-UHFFFAOYSA-N
External Identifiers	ChEMBL [CHEMBL352400]; PubChem [10911621];
Reference of Component-Ingredient Pair	N/A

Occurrence of the ingredient across TCM components

Component ID	Latin Name	Pinyin Name	Chinese Name
TCMH2128	Rhizoma bolbostemmae	Tu Bei Mu	土贝母

Ingredient ID: TCMC4321
Formula: C32H44O8

Common Name	Cucurbitacin E
IUPAC Name	[(E,6R)-6-[(8S,9R,10R,13R,14S,16R,17R)-2,16-dihydroxy-4,4,9,13,14-pentamethyl-3,11-dioxo-8,10,12,15,16,17-hexahydro-7H-cyclopenta[a]phenanthren-17-yl]-6-hydroxy-2-methyl-5-oxohept-3-en-2-yl] acetate
Canonical SMILES	CC(=O)OC(/C=C/C(=O)[C@@]([C@H]1[C@H](O)C[C@@]2([C@]1(C)CC(=O)[C@@]1([C@H]2CC=C2[C@H]1C=C(O)C(=O)C2(C)C)C)C)(O)C)(C)C
Standard InCHI	InChI=1S/C32H44O8/c1-17(33)40-27(2,3)13-12-23(36)32(9,39)25-21(35)15-29(6)22-11-10-18-19(14-20(34)26(38)28(18,4)5)31(22,8)24(37)16-30(25,29)7/h10,12-14,19,21-22,25,34-35,39H,11,15-16H2,1-9H3/b13-12+/t19-,21-,22+,25+,29+,30-,31+,32+/m1/s1
Standard InCHIKey	NDYMQXYDSVBNLL-MUYMLXPFSA-N
External Identifiers	ChEMBL [CHEMBL455056]; PubChem [5281319];
Reference of Component-Ingredient Pair	22842972

Occurrence of the ingredient across TCM components

Component ID	Latin Name	Pinyin Name	Chinese Name
TCMH2128	Rhizoma bolbostemmae	Tu Bei Mu	土贝母

Ingredient ID: TCMC3815
Formula: C4H6N4O3

Common Name	(R)-Allantoin,Allantoin
IUPAC Name	[(4R)-2,5-dioxoimidazolidin-4-yl]urea
Canonical SMILES	NC(=O)N[C@@H]1NC(=O)NC1=O
Standard InCHI	InChI=1S/C4H6N4O3/c5-3(10)6-1-2(9)8-4(11)7-1/h1H,(H3,5,6,10)(H2,7,8,9,11)/t1-/m1/s1
Standard InCHIKey	POJWUDADGALRAB-PVQJCKRUSA-N
External Identifiers	ChEMBL [N/A]; PubChem [439713];
Reference of Component-Ingredient Pair	17428786

Occurrence of the ingredient across TCM components

Component ID	Latin Name	Pinyin Name	Chinese Name
TCMH677	Pueraria lobata	Ge Gen	葛根
TCMH1397	Aristolochia debilis	Ma Dou Ling	马兜铃
TCMH1845	Dioscorea batatas	Shan Yao	山药
TCMH2128	Rhizoma bolbostemmae	Tu Bei Mu	土贝母

Ingredient ID: TCMC3678
Formula: C12H22O11

Common Name	4-O-A-D-Glucopyranosyl-D-Glucose
IUPAC Name	(2R,3R,4R,5R)-2,3,5,6-tetrahydroxy-4-[(2R,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxyhexanal
Canonical SMILES	OC[C@H]([C@H]([C@@H]([C@H](C=O)O)O)O[C@H]1O[C@H](CO)[C@H]([C@@H]([C@H]1O)O)O)O
Standard InCHI	InChI=1S/C12H22O11/c13-1-4(16)7(18)11(5(17)2-14)23-12-10(21)9(20)8(19)6(3-15)22-12/h1,4-12,14-21H,2-3H2/t4-,5+,6+,7+,8+,9-,10+,11+,12+/m0/s1
Standard InCHIKey	DKXNBNKWCZZMJT-WUJBLJFYSA-N
External Identifiers	ChEMBL [N/A]; PubChem [181526];
Reference of Component-Ingredient Pair	22237946

Occurrence of the ingredient across TCM components

Component ID	Latin Name	Pinyin Name	Chinese Name
TCMH2128	Rhizoma bolbostemmae	Tu Bei Mu	土贝母

Ingredient ID: TCMC3399
Formula: C6H12O6

Common Name	D-Glucose,Glucose
IUPAC Name	(2R,3S,4R,5R)-2,3,4,5,6-pentahydroxyhexanal
Canonical SMILES	OC[C@H]([C@H]([C@@H]([C@H](C=O)O)O)O)O
Standard InCHI	InChI=1S/C6H12O6/c7-1-3(9)5(11)6(12)4(10)2-8/h1,3-6,8-12H,2H2/t3-,4+,5+,6+/m0/s1
Standard InCHIKey	GZCGUPFRVQAUEE-SLPGGIOYSA-N
External Identifiers	ChEMBL [N/A]; PubChem [107526];
Reference of Component-Ingredient Pair	18071748

Occurrence of the ingredient across TCM components

Component ID	Latin Name	Pinyin Name	Chinese Name
TCMH1329	Arillus longan	Long Yan Rou	龙眼肉
TCMH2084	Asparagus cochinchinensis	Tian Dong	天冬
TCMH2128	Rhizoma bolbostemmae	Tu Bei Mu	土贝母
TCMH2102	Concretio silicea bambusae	Tian Zhu Huang	天竺黄
TCMH451	Rehmannia glutinosa	Di Huang	地黄

Ingredient ID: TCMC3089
Formula: C6H7NO

Common Name	2-Acetyl-1H-Pyrrole
IUPAC Name	1-(1H-pyrrol-2-yl)ethanone
Canonical SMILES	CC(=O)c1ccc[nH]1
Standard InCHI	InChI=1S/C6H7NO/c1-5(8)6-3-2-4-7-6/h2-4,7H,1H3
Standard InCHIKey	IGJQUJNPMOYEJY-UHFFFAOYSA-N
External Identifiers	ChEMBL [CHEMBL1414126]; PubChem [14079];
Reference of Component-Ingredient Pair	22871255

Occurrence of the ingredient across TCM components

Component ID	Latin Name	Pinyin Name	Chinese Name
TCMH2128	Rhizoma bolbostemmae	Tu Bei Mu	土贝母

Ingredient ID: TCMC3069
Formula: C31H64

Common Name	Hentriacontane
IUPAC Name	hentriacontane
Canonical SMILES	CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
Standard InCHI	InChI=1S/C31H64/c1-3-5-7-9-11-13-15-17-19-21-23-25-27-29-31-30-28-26-24-22-20-18-16-14-12-10-8-6-4-2/h3-31H2,1-2H3
Standard InCHIKey	IUJAMGNYPWYUPM-UHFFFAOYSA-N
External Identifiers	ChEMBL [CHEMBL257490]; PubChem [12410];
Reference of Component-Ingredient Pair	22359371

Occurrence of the ingredient across TCM components

Component ID	Latin Name	Pinyin Name	Chinese Name
TCMH241	Plantago asiatica	Che Qian Zi	车前子
TCMH1368	Apocyni veneti folium	Luo Bu Ma Ye	罗布麻叶
TCMH2128	Rhizoma bolbostemmae	Tu Bei Mu	土贝母
TCMH2507	Epimedium brevicornum	Yin Yang Huo	淫羊藿
TCMH1219	Semen armeniacae amarum	Ku Xing Ren	苦杏仁

Ingredient ID: TCMC3068
Formula: C29H60

Common Name	Nonacosane
IUPAC Name	nonacosane
Canonical SMILES	CCCCCCCCCCCCCCCCCCCCCCCCCCCCC
Standard InCHI	InChI=1S/C29H60/c1-3-5-7-9-11-13-15-17-19-21-23-25-27-29-28-26-24-22-20-18-16-14-12-10-8-6-4-2/h3-29H2,1-2H3
Standard InCHIKey	IGGUPRCHHJZPBS-UHFFFAOYSA-N
External Identifiers	ChEMBL [CHEMBL428955]; PubChem [12409];
Reference of Component-Ingredient Pair	22292044

Occurrence of the ingredient across TCM components

Component ID	Latin Name	Pinyin Name	Chinese Name
TCMH389	Gleditsiae sinensis fructus	Da Zao Jiao	大皂角
TCMH524	Eucommia ulmoides	Du Zhong	杜仲
TCMH865	Carthamus tinctorius	Hong Hua	红花
TCMH1368	Apocyni veneti folium	Luo Bu Ma Ye	罗布麻叶
TCMH877	Radix ginseng rubra	Hong Shen	红参
TCMH1813	Asarum sagittarioides	Shan Ci Gu	山慈菇
TCMH2128	Rhizoma bolbostemmae	Tu Bei Mu	土贝母
TCMH1721	Panax ginseng	Ren Shen	人参
TCMH2641	Gardenia jasminoides	Zhi Zi	栀子
TCMH2252	Agrimonia pilosa var. japonica	Xian He Cao	仙鹤草
TCMH2693	Fructus gleditsiae abnormalis	Zhu Ya Zao	猪牙皂
TCMH925	Exocarpium citri grandis	Hua Ju Hong	化橘红
TCMH1219	Semen armeniacae amarum	Ku Xing Ren	苦杏仁

Ingredient ID: TCMC2886
Formula: C12H22O11

Common Name	Sucrose
IUPAC Name	(2R,3R,4S,5S,6R)-2-[(2S,3S,4S,5R)-3,4-dihydroxy-2,5-bis(hydroxymethyl)oxolan-2-yl]oxy-6-(hydroxymethyl)oxane-3,4,5-triol
Canonical SMILES	OC[C@H]1O[C@@]([C@H]([C@@H]1O)O)(CO)O[C@H]1O[C@H](CO)[C@H]([C@@H]([C@H]1O)O)O
Standard InCHI	InChI=1S/C12H22O11/c13-1-4-6(16)8(18)9(19)11(21-4)23-12(3-15)10(20)7(17)5(2-14)22-12/h4-11,13-20H,1-3H2/t4-,5-,6-,7-,8+,9-,10+,11-,12+/m1/s1
Standard InCHIKey	CZMRCDWAGMRECN-UGDNZRGBSA-N
External Identifiers	ChEMBL [CHEMBL253582]; PubChem [5988];
Reference of Component-Ingredient Pair	29968805

Occurrence of the ingredient across TCM components

Component ID	Latin Name	Pinyin Name	Chinese Name
TCMH381	Isatis indigotica	Da Qing Ye	大青叶
TCMH206	Fructus xanthii sibirici	Cang Er Zi	苍耳子
TCMH240	Plantago depressa	Che Qian Cao	车前草
TCMH90	Imperata cylindrica	Bai Mao Gen	白茅根
TCMH241	Plantago asiatica	Che Qian Zi	车前子
TCMH182	Areca catechu	Bing Lang	槟榔
TCMH127	Isatis indigotica	Ban Lan Gen	板蓝根
TCMH562	Saposhnikovia divaricata	Fang Feng	防风
TCMH327	Eleutherococcus senticosus	Ci Wu Jia	刺五加
TCMH273	Fritillaria cirrhosa	Chuan Bei Mu	川贝母
TCMH45	Lablab purpureus	Bai Bian Dou	白扁豆
TCMH388	Ziziphus jujuba	Da Zao	大枣
TCMH981	Astragalus membranaceus	Huang Qi	黄芪
TCMH986	Scutellaria baicalensis	Huang Qin	黄芩
TCMH1329	Arillus longan	Long Yan Rou	龙眼肉
TCMH1343	Aloe vera	Lu Hui	芦荟
TCMH1396	Portulaca oleracea	Ma Chi Xian	马齿苋
TCMH1953	Pyrrosia lingua	Shi Wei	石韦
TCMH1665	Notopterygium incisum	Qiang Huo	羌活
TCMH1848	Crataegus pinnatifida	Shan Zha	山楂
TCMH1862	Cornus officinalis	Shan Zhu Yu	山茱萸
TCMH2084	Asparagus cochinchinensis	Tian Dong	天冬
TCMH2128	Rhizoma bolbostemmae	Tu Bei Mu	土贝母
TCMH1721	Panax ginseng	Ren Shen	人参
TCMH2090	Gastrodia elata	Tian Ma	天麻
TCMH1798	Morus alba	Sang Zhi	桑枝
TCMH2684	Ardisia crenata	Zhu Sha Gen	朱砂根
TCMH2241	Panax quinquefolium	Xi Yang Shen	西洋参
TCMH451	Rehmannia glutinosa	Di Huang	地黄

Ingredient ID: TCMC1530
Formula: C6H6O3

Common Name	Maltol
IUPAC Name	3-hydroxy-2-methylpyran-4-one
Canonical SMILES	O=c1ccoc(c1O)C
Standard InCHI	InChI=1S/C6H6O3/c1-4-6(8)5(7)2-3-9-4/h2-3,8H,1H3
Standard InCHIKey	XPCTZQVDEJYUGT-UHFFFAOYSA-N
External Identifiers	ChEMBL [CHEMBL31422]; PubChem [8369];
Reference of Component-Ingredient Pair	22542289

Occurrence of the ingredient across TCM components

Component ID	Latin Name	Pinyin Name	Chinese Name
TCMH2128	Rhizoma bolbostemmae	Tu Bei Mu	土贝母
TCMH260	Semen phaseoli	Chi Xiao Dou	赤小豆
TCMH422	Angelica sinensis	Dang Gui Gan Jin Gao	当归干浸膏
TCMH1839	Panax ginseng	Shan Shen	山参
TCMH2726	Pterocarpus indicus	Zi Tan	紫檀
TCMH255	Vigna angularis	Chi Dou	赤豆
TCMH494	Cordyceps sinensis	Dong Chong Xia Cao	冬虫夏草
TCMH1428	Ophiopogon japonicus	Mai Men Dong	麦门冬
TCMH1777	Panax notoginseng	San Qi Ye Jing	三七叶茎
TCMH421	Angelica sinensis	Dang Gui	当归
TCMH1770	Panax notoginseng	San Qi Gan Jin Gao	三七干浸膏
TCMH1771	Panax notoginseng	San Qi Gao Fen	三七膏粉
TCMH1772	Panax notoginseng	San Qi Hua	三七花
TCMH1774	Panax notoginseng	San Qi Jing Ye	三七茎叶
TCMH1776	Panax notoginseng	San Qi Ye	三七叶
TCMH1721	Panax ginseng	Ren Shen	人参
TCMH1728	Panax ginseng	Ren Shen Ye	人参叶
TCMH1423	Ophiopogon japonicus	Mai Dong	麦冬
TCMH1424	Ophiopogon japonicus	Mai Dong Men	麦冬门
TCMH1425	Ophiopogon japonicus	Mai Dong Rou	麦冬肉

Properties

Ingredient ID	Formulae	Name	MW	AlogP	MlogP	XlogP	# HBA	# HBD	PSA	# Rotatable Bond	# Ring	# Heacy Atom	Lipinski RO5 Violation
TCMC1530	C6H6O3	Maltol	126.03	-0.6804	1.79	0.907	3	1	46.53	2	1	9	0
TCMC2886	C12H22O11	Sucrose	342.1162115	-4.3105	1.57	-3.277	11	8	189.53	5	2	23	2
TCMC3068	C29H60	Nonacosane	408.4695019	-7.6734	4.65	16.841	0	0	0	26	0	29	2
TCMC3069	C31H64	Hentriacontane	436.500802	-8.2494	4.87	17.979	0	0	0	28	0	31	2
TCMC3089	C6H7NO	2-Acetyl-1H-Pyrrole	109.0527638	-0.6743	1.9	0.712	2	1	32.86	1	1	8	0
TCMC3399	C6H12O6	D-Glucose,Glucose	180.0633881	-2.7906	1.46	-3.325	6	5	118.22	5	0	12	0
TCMC3678	C12H22O11	4-O-A-D-Glucopyranosyl-D-Glucose	342.1162115	-4.5375	1.57	-4.433	11	8	197.37	8	1	23	2
TCMC3815	C4H6N4O3	(R)-Allantoin,Allantoin	158.0439901	-1.2413	1.13	-1.169	7	4	113.32	2	1	11	0
TCMC4321	C32H44O8	Cucurbitacin E	556.3036184	1.1668	4.1	3.404	8	3	138.2	6	4	40	0
TCMC5527	C12H17NO4	Methyl 4-[2-Formyl-5-(Methoxymethyl)Pyrrol-1-Yl]Butanoate	239.115758	-0.4498	2.23	1.203	5	0	57.53	8	1	17	0
TCMC6309	C29H50O	24-Ethylcholesterol,Beta-Sitosterol	414.3861662	1.3	4.54	11.595	1	1	20.23	6	4	30	1

Download Data

All data can be downloaded by:

→ Selecting data type in the below download table
→ Then click the download button.

Data Section	Select to Download
1. General Information of the Component
2. TCM Prescriptions with the Component
3. Putative Targets
4. Activity & References for Filtering Putative Targets
5. Ingredient Data & Chemical Structure Information (Properties, InChI, InChIkey, SMILES, etc.)

Component: Rhizoma bolbostemmae 土贝母

Description of the Component

Component ID

Latin Name

English Name

Chinese Pinyin Name

中文名

TCM Properties

TCM Meridians

Therapeutic Class English

Therapeutic Class Chinese

Functions

Toxicity

Geo-authentic habitats (道地产区)

Reference

Barcode ID

Barcode Source

TCM Prescriptions with the Component

Targeted Human Proteins by the Ingredient of Component

Targeted Pathogenic Microbes by the Ingredient of Component

Ingredient Structrues

Ingredient ID: TCMC6309

Occurrence of the ingredient across TCM components

Ingredient ID: TCMC5527

Occurrence of the ingredient across TCM components

Ingredient ID: TCMC4321

Occurrence of the ingredient across TCM components

Ingredient ID: TCMC3815

Occurrence of the ingredient across TCM components

Ingredient ID: TCMC3678

Occurrence of the ingredient across TCM components

Ingredient ID: TCMC3399

Occurrence of the ingredient across TCM components

Ingredient ID: TCMC3089

Occurrence of the ingredient across TCM components

Ingredient ID: TCMC3069

Occurrence of the ingredient across TCM components

Ingredient ID: TCMC3068

Occurrence of the ingredient across TCM components

Ingredient ID: TCMC2886

Occurrence of the ingredient across TCM components

Ingredient ID: TCMC1530

Occurrence of the ingredient across TCM components

Properties

Download Data