Component: Panax quinquefolium 西洋参


Description of the Component

Component ID
TCMH2241
Latin Name
Panax quinquefolium
English Name
American ginseng
Chinese Pinyin Name
Xi Yang Shen
中文名
西洋参
TCM Properties
Cold,Sweet,Slightly Bitter
TCM Meridians
Lung,Heart,Kidney
Therapeutic Class English
For tonifying weakness
Therapeutic Class Chinese
补虚
Functions
replenish qi and promote body fluids, nourish yin and clear heat
Toxicity
NA
Geo-authentic habitats (道地产区)
Hebei Province,Beijing,Tianjin
Reference
Chinese Pharmacopoeia (2015)
Barcode ID
KY120319
Barcode Source
GenBank

TCM Prescriptions with the Component

Prescription ID Prescription English Name Prescription Chinese Name
TCMF2369 Diabetes Relieving Decorction 姜糖饮
TCMF3568 Ding Kun Pills 定坤丸
TCMF8 Er Shi Qi Wei Ding Kun Pills 二十七味定坤丸
TCMF7143 Fu Fang Yan Hu Suo Spray 复方延胡索喷雾剂
TCMFx6994 Fu Fang Yang Shen Wang Jiang Capsules 复方洋参王浆胶囊
TCMFx775 Fu Fang Zao Fan Pills 复方皂矾丸
TCMFx3347 Fu Fang Zao Fan Pills 复方皂矾丸
TCMF2253 Heat Cooling Qi Enhancing Decoction
TCMF4426 Heng Zhi Ke Chuan Capsules 恒制咳喘胶囊
TCMF6953 Jian Yan Ling 健延龄
TCMFx1513 Oral Liquid of American Ginseng and Royal Jelly 西洋参蜂王浆
TCMFx699 Shen Yan Kang Fu Tablet 肾炎康复片
TCMF7106 Sheng Mo Zeng Ye Tong Capsules 生脉增液通胶囊
TCMF5258 Tan Chuan Ban Xia Granules 痰喘半夏颗粒
TCMFx6959 Tie Pi Feng Dou Granules 铁皮枫斗颗粒
TCMFx5808 Tong Bian Xiao Cuo Capsules 通便消痤胶囊
TCMF6760 Yang Shen Bao Fei Pills 洋参保肺丸
TCMF850 Yang Can Bao Fei Pills 洋参保肺丸
TCMF6965 Zhi Qi Oral Liquid 脂芪口服液
TCMF1968 ZYMDSG Decoction

Targeted Human Proteins by the Ingredient of Component

Target ID Gene Symbol Target Name Target Class Uniprot ID
TCMT1 EHMT2 Histone-lysine N-methyltransferase, H3 lysine-9 specific 3 Transferase Q96KQ7
TCMT11 HIF1A Hypoxia-inducible factor 1 alpha Transcription factor Q16665
TCMT126 TERT Telomerase reverse transcriptase Transferase O14746
TCMT133 CA1 Carbonic anhydrase I Lyase P00915
TCMT134 CA2 Carbonic anhydrase II Lyase P00918
TCMT150 RORC Nuclear receptor ROR-gamma Nuclear receptor P51449
TCMT156 CYP19A1 Cytochrome P450 19A1 Oxidoreductase P11511
TCMT17 POLB DNA polymerase beta Transferase P06746
TCMT176 SOAT1 Acyl coenzyme A:cholesterol acyltransferase 1 Transferase P35610
TCMT189 DUSP3 Dual specificity protein phosphatase 3 Hydrolase P51452
TCMT2 MAPT Microtubule-associated protein tau Unclassified P10636
TCMT223 AKR1B1 Aldose reductase Oxidoreductase P15121
TCMT248 CXCL8 Interleukin-8 Unclassified P10145
TCMT297 FABP4 Fatty acid binding protein adipocyte Unclassified P15090
TCMT298 FABP3 Fatty acid binding protein muscle Hydrolase P05413
TCMT3 ALOX15 Arachidonate 15-lipoxygenase Oxidoreductase P16050
TCMT33 CYP3A4 Cytochrome P450 3A4 Oxidoreductase P08684
TCMT333 CTBP2 C-terminal-binding protein 2 Unclassified P56545
TCMT46 F3 Coagulation factor III Unclassified P13726
TCMT558 TOP2A DNA topoisomerase II alpha Isomerase P11388
TCMT598 TOP1 DNA topoisomerase I Isomerase P11387
TCMT6 NFKB1 Nuclear factor NF-kappa-B p105 subunit Transcription factor P19838
TCMT63 PPARA Peroxisome proliferator-activated receptor alpha Nuclear receptor Q07869
TCMT64 PPARD Peroxisome proliferator-activated receptor delta Nuclear receptor Q03181
TCMT67 PPARG Peroxisome proliferator-activated receptor gamma Nuclear receptor P37231
TCMT683 MIF Macrophage migration inhibitory factor Isomerase P14174
TCMT8 KDM4E Lysine-specific demethylase 4D-like Oxidoreductase B2RXH2
TCMT80 MAPK1 MAP kinase ERK2 Kinase P28482
TCMT808 FABP5 Fatty acid binding protein epidermal Unclassified Q01469
TCMT809 FABP2 Fatty acid binding protein intestinal Unclassified P12104
TCMT810 TLR2 Toll-like receptor 2 Unclassified O60603
TCMT82 ESR1 Estrogen receptor alpha Nuclear receptor P03372


Targeted Pathogenic Microbes by the Ingredient of Component

Target ID Target Name
TCMT1218 Staphylococcus aureus
TCMT1253 Penicillium chrysogenum
TCMT1361 Neisseria meningitidis
TCMT1382 Plasmodium falciparum (isolate K1 / Thailand)
TCMT1438 Plasmodium falciparum
TCMT1442 Leishmania donovani
TCMT1454 Bacillus subtilis
TCMT1462 Streptococcus mutans

Ingredient Structrues

Ingredient ID: TCMC845
Formula: C15H24O

Ingredient ID: TCMC7341
Formula: C42H72O13

Ingredient ID: TCMC7226
Formula: C57H94O26

Ingredient ID: TCMC7208
Formula: C56H94O24

Ingredient ID: TCMC7166
Formula: C19H26O3

Ingredient ID: TCMC7115
Formula: C17H22O2

Ingredient ID: TCMC7013
Formula: C17H24O2

Ingredient ID: TCMC6991
Formula: C18H30

Ingredient ID: TCMC6446
Formula: C18H32O16

Ingredient ID: TCMC6261
Formula: C15H24

Ingredient ID: TCMC6007
Formula: C11H22O2

Ingredient ID: TCMC5975
Formula: C36H62O9

Ingredient ID: TCMC5806
Formula: C48H76O19

Ingredient ID: TCMC5759
Formula: C48H82O18

Ingredient ID: TCMC5578
Formula: C19H34O7

Ingredient ID: TCMC5325
Formula: C15H24

Ingredient ID: TCMC5255
Formula: C54H92O23

Ingredient ID: TCMC5173
Formula: C53H90O22

Ingredient ID: TCMC4556
Formula: C15H24

Ingredient ID: TCMC4418
Formula: C18H32O16

Ingredient ID: TCMC4336
Formula: C15H24

Ingredient ID: TCMC3900
Formula: C10H16O

Ingredient ID: TCMC3884
Formula: C15H22

Ingredient ID: TCMC3859
Formula: C42H72O14

Ingredient ID: TCMC3857
Formula: C48H82O18

Ingredient ID: TCMC3714
Formula: C18H32O16

Ingredient ID: TCMC3132
Formula: C17H28

Ingredient ID: TCMC3091
Formula: C12H18

Ingredient ID: TCMC3080
Formula: C15H24

Ingredient ID: TCMC3025
Formula: C16H34

Ingredient ID: TCMC3006
Formula: C17H34O2

Ingredient ID: TCMC2965
Formula: C12H26

Ingredient ID: TCMC2959
Formula: C9H18O2

Ingredient ID: TCMC2886
Formula: C12H22O11

Ingredient ID: TCMC2105
Formula: C18H36O2

Ingredient ID: TCMC1876
Formula: C7H5NS

Ingredient ID: TCMC1838
Formula: C20H21NO4.ClH

Ingredient ID: TCMC1830
Formula: C16H32O2

Ingredient ID: TCMC1777
Formula: C8H18O

Ingredient ID: TCMC1776
Formula: C8H16O2

Ingredient ID: TCMC1495
Formula: C18H32O2

Ingredient ID: TCMC1389
Formula: C10H12O2

Ingredient ID: TCMC1323
Formula: C6H12O2

Ingredient ID: TCMC1317
Formula: C7H14O2

Properties

Ingredient ID Formulae Name MW AlogP MlogP XlogP # HBA # HBD PSA # Rotatable Bond # Ring # Heacy Atom Lipinski RO5 Violation
TCMC845 C15H24O Butylated Hydroxytoluene 220.18 3.2941 3 5.957 0 1 20.23 10 1 16 1
TCMC1317 C7H14O2 Heptanoate 130.1 -1.3057 2.01 2.449 2 1 37.3 7 0 9 0
TCMC1323 C6H12O2 Hexanoate 116.08 -1.0177 1.9 1.88 2 1 37.3 6 0 8 0
TCMC1389 C10H12O2 Isoeugenol 164.08 0.3952 2.34 2.805 0 1 29.46 5 1 12 0
TCMC1495 C18H32O2 Linoleic Acid 280.24 -0.9485 3.22 7.865 2 1 37.3 16 0 20 2
TCMC1776 C8H16O2 Octanoic Acid 144.12 -1.5937 2.12 3.018 2 1 37.3 8 0 10 0
TCMC1777 C8H18O Octanol 130.14 -2.1254 2.23 3.127 1 1 20.23 8 0 9 0
TCMC1830 C16H32O2 Palmitic Acid 256.24 -3.8977 3 7.57 2 1 37.3 16 0 18 2
TCMC1838 C20H21NO4.ClH Papaverine Hydrochloride 339.15 0.114 3.11 3.363 1 0 49.81 10 3 25 0
TCMC1876 C7H5NS Phenylisothiocyanate 135.01 0.2643 2.01 4.164 1 0 44.45 1 1 9 0
TCMC2105 C18H36O2 Stearic Acid 284.27 -4.4737 3.22 8.708 2 1 37.3 18 0 20 2
TCMC2886 C12H22O11 Sucrose 342.1162115 -4.3105 1.57 -3.277 11 8 189.53 5 2 23 2
TCMC2959 C9H18O2 Nonanoic Acid 157.1228548 -2.5595 2.23 3.106 2 0 40.13 7 0 11 0
TCMC2965 C12H26 Dodecane 170.2034508 -2.7774 2.78 7.168 0 0 0 9 0 12 1
TCMC3006 C17H34O2 Daturic Acid,Heptadecanoic Acid,Margaric Acid 269.2480553 -4.8635 3.11 7.658 2 0 40.13 15 0 19 2
TCMC3025 C16H34 Hexadecane 226.2660511 -3.9294 3.22 9.444 0 0 0 13 0 16 2
TCMC3080 C15H24 1,3,5-Triisopropylphene 204.1878008 1.7187 3.11 8.262 0 0 0 3 1 15 1
TCMC3091 C12H18 1-Phenylhexane 162.1408506 -1.0383 2.78 7.23 0 0 0 5 1 12 1
TCMC3132 C17H28 6-Phenylundecane 232.2191009 -1.4203 3.33 10.014 0 0 0 9 1 17 1
TCMC3714 C18H32O16 Panose C 504.1690349 -6.0574 1.68 -5.243 16 11 268.68 8 3 34 2
TCMC3857 C48H82O18 Ginsenoside Re 946.5501158 -2.9721 4.76 3.039 18 12 298.14 12 7 66 3
TCMC3859 C42H72O14 Ginsenoside Rg1 800.492207 -1.7252 4.54 3.873 14 10 239.22 10 6 56 2
TCMC3884 C15H22 Α-Curcumene,Α-Curcumene(R-) 202.1721507 2.8428 3.11 7.712 0 0 0 4 1 15 1
TCMC3900 C10H16O Pulegone 152.1201151 1.583 2.45 2.126 1 0 17.07 0 1 11 0
TCMC4336 C15H24 (1R,9S)-4,11,11-Trimethyl-8-Methylenebicyclo[7.2.0]Undec-4-Ene,Caryophellene,Β-Caryophyllene 204.1878008 3.2289 3.11 6.044 0 0 0 0 2 15 1
TCMC4418 C18H32O16 Panose B 504.1690349 -6.0072 1.68 -5.2 16 11 268.68 7 3 34 2
TCMC4556 C15H24 Β-Farnesene 204.1878008 4.3258 3.11 5.992 0 0 0 7 0 15 1
TCMC5173 C53H90O22 Ginsenoside Rb2 1078.592375 -3.942 4.87 2.916 22 14 357.06 15 8 75 3
TCMC5255 C54H92O23 Ginsenoside Rb1 1108.602939 -4.4527 4.87 2.673 23 15 377.29 16 8 77 3
TCMC5325 C15H24 (S)-1-Methyl-4-(6-Methylhepta-1,5-Dien-2-Yl)Cyclohex-1-Ene,Β-Bisabolene 204.1878008 3.3746 3.11 5.551 0 0 0 4 1 15 1
TCMC5578 C19H34O7 Linarionoside A 374.2304534 -1.185 2.78 0.473 7 5 119.61 6 2 26 0
TCMC5759 C48H82O18 Ginsenoside Rd 946.5501158 -2.7058 4.76 4.21 18 12 298.14 13 7 66 3
TCMC5806 C48H76O19 Ginsenoside R0 955.4902552 -3.844 4.65 4.348 19 10 314.88 10 8 67 2
TCMC5975 C36H62O9 Ginsenoside-Rh1 638.4393836 0.0217 4.43 4.981 9 7 160.07 7 5 45 1
TCMC6007 C11H22O2 8-Methyl Capric Acid 185.1541549 -1.8825 2.45 4.183 2 0 40.13 8 0 13 0
TCMC6261 C15H24 (1Ar,7R,7Ar,7Bs)-1,1,7,7A-Tetramethyl-1A,2,3,5,6,7,7A,7B-Octahydro-1H-Cyclopropa[A]Naphthalene,Calarene 204.1878008 2.3854 3.11 6.298 0 0 0 0 3 15 1
TCMC6446 C18H32O16 Panose 504.1690349 -6.0072 1.68 -5.2 16 11 268.68 7 3 34 2
TCMC6991 C18H30 3-Phenyldodecane 246.234751 -2.2519 3.44 10.583 0 0 0 10 1 18 1
TCMC7013 C17H24O2 Panaxydol 260.17763 -0.4916 3.11 4.427 2 1 32.76 8 1 19 0
TCMC7115 C17H22O2 Ginsenoyne E 258.1619799 -0.3514 3.11 4.887 2 0 29.6 8 1 19 0
TCMC7166 C19H26O3 Acetyl Panaxydol 302.1881947 -0.1125 3.22 5.167 3 0 38.83 10 1 22 1
TCMC7208 C56H94O24 Quinquenoside R1 1150.613504 -4.0736 4.98 2.984 24 14 383.36 18 8 80 3
TCMC7226 C57H94O26 6'-Malonylginsenoside Rd1 1193.595508 -4.9663 4.87 2.284 26 14 423.49 20 8 83 3
TCMC7341 C42H72O13 Ginsenoside Rg2 784.4972924 -1.2252 4.65 4.147 13 9 218.99 9 6 55 2

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