Component ID |
TCMH1576 |
Latin Name |
Bubalus bubalis |
English Name |
Buffalo horn |
Chinese Pinyin Name |
Niu Jiao Jian Fen |
中文名 |
牛角尖粉 |
TCM Properties |
|
TCM Meridians |
|
Therapeutic Class English |
|
Therapeutic Class Chinese |
|
Functions |
|
Toxicity |
NA |
Geo-authentic habitats (道地产区) |
NA |
Reference |
Chinese Pharmacopoeia (2015) |
Barcode ID |
GBMA0080-06 |
Barcode Source |
BOLDSYSTEMS |
Prescription ID | Prescription English Name | Prescription Chinese Name |
---|---|---|
TCMFx934 | Yi Xin Pills | 益心丸 |
Target ID | Gene Symbol | Target Name | Target Class | Uniprot ID |
---|---|---|---|---|
TCMT1 | EHMT2 | Histone-lysine N-methyltransferase, H3 lysine-9 specific 3 | Transferase | Q96KQ7 |
TCMT105 | SLC15A2 | Solute carrier family 15 member 2 | Transporter | Q16348 |
TCMT11 | HIF1A | Hypoxia-inducible factor 1 alpha | Transcription factor | Q16665 |
TCMT125 | GBA | Beta-glucocerebrosidase | Hydrolase | P04062 |
TCMT13 | APEX1 | DNA-(apurinic or apyrimidinic site) lyase | Lyase | P27695 |
TCMT150 | RORC | Nuclear receptor ROR-gamma | Nuclear receptor | P51449 |
TCMT156 | CYP19A1 | Cytochrome P450 19A1 | Oxidoreductase | P11511 |
TCMT162 | UGT1A1 | UDP-glucuronosyltransferase 1-1 | Transferase | P22309 |
TCMT175 | GPBAR1 | G-protein coupled bile acid receptor 1 | GPCR | Q8TDU6 |
TCMT187 | AR | Androgen Receptor | Nuclear receptor | P10275 |
TCMT2 | MAPT | Microtubule-associated protein tau | Unclassified | P10636 |
TCMT213 | SLC22A1 | Solute carrier family 22 member 1 | Transporter | O15245 |
TCMT223 | AKR1B1 | Aldose reductase | Oxidoreductase | P15121 |
TCMT243 | ADRA2C | Alpha-2c adrenergic receptor | GPCR | P18825 |
TCMT247 | ADRA2A | Alpha-2a adrenergic receptor | GPCR | P08913 |
TCMT248 | CXCL8 | Interleukin-8 | Unclassified | P10145 |
TCMT267 | GABRR1 | GABA receptor rho-1 subunit | Ion channel | P24046 |
TCMT27 | DRD1 | Dopamine D1 receptor | GPCR | P21728 |
TCMT273 | NR1H4 | Bile acid receptor FXR | Nuclear receptor | Q96RI1 |
TCMT276 | SLCO2B1 | Solute carrier organic anion transporter family member 2B1 | Transporter | O94956 |
TCMT277 | SLCO1B3 | Solute carrier organic anion transporter family member 1B3 | Transporter | Q9NPD5 |
TCMT278 | SLCO1B1 | Solute carrier organic anion transporter family member 1B1 | Transporter | Q9Y6L6 |
TCMT279 | VDR | Vitamin D receptor | Nuclear receptor | P11473 |
TCMT297 | FABP4 | Fatty acid binding protein adipocyte | Unclassified | P15090 |
TCMT298 | FABP3 | Fatty acid binding protein muscle | Hydrolase | P05413 |
TCMT33 | CYP3A4 | Cytochrome P450 3A4 | Oxidoreductase | P08684 |
TCMT341 | NR1I2 | Pregnane X receptor | Nuclear receptor | O75469 |
TCMT38 | DRD2 | Dopamine D2 receptor | GPCR | P14416 |
TCMT42 | KMT2A | Histone-lysine N-methyltransferase MLL | Transferase | Q03164 |
TCMT559 | ADRB2 | Beta-2 adrenergic receptor | GPCR | P07550 |
TCMT588 | DAO | D-amino-acid oxidase | Oxidoreductase | P14920 |
TCMT6 | NFKB1 | Nuclear factor NF-kappa-B p105 subunit | Transcription factor | P19838 |
TCMT63 | PPARA | Peroxisome proliferator-activated receptor alpha | Nuclear receptor | Q07869 |
TCMT64 | PPARD | Peroxisome proliferator-activated receptor delta | Nuclear receptor | Q03181 |
TCMT643 | ADRA1A | Alpha-1a adrenergic receptor | GPCR | P35348 |
TCMT647 | ADRA2B | Alpha-2b adrenergic receptor | GPCR | P18089 |
TCMT650 | ADRA1B | Alpha-1b adrenergic receptor | GPCR | P35368 |
TCMT67 | PPARG | Peroxisome proliferator-activated receptor gamma | Nuclear receptor | P37231 |
TCMT69 | THRB | Thyroid hormone receptor beta-1 | Nuclear receptor | P10828 |
TCMT737 | APOBEC3G | DNA dC->dU-editing enzyme APOBEC-3G | Unclassified | Q9HC16 |
TCMT796 | PCNA | Proliferating cell nuclear antigen | Unclassified | P12004 |
TCMT80 | MAPK1 | MAP kinase ERK2 | Kinase | P28482 |
TCMT808 | FABP5 | Fatty acid binding protein epidermal | Unclassified | Q01469 |
TCMT809 | FABP2 | Fatty acid binding protein intestinal | Unclassified | P12104 |
TCMT810 | TLR2 | Toll-like receptor 2 | Unclassified | O60603 |
TCMT864 | THRA | Thyroid hormone receptor alpha | Nuclear receptor | P10827 |
Target ID | Target Name |
---|---|
TCMT1170 | Enterobacter cloacae |
TCMT1176 | Streptococcus pneumoniae |
TCMT1177 | Haemophilus influenzae |
TCMT1193 | Staphylococcus |
TCMT1194 | Shigella sonnei |
TCMT1195 | Streptococcus pasteurianus |
TCMT1196 | Salmonella |
TCMT1197 | Shigella sp. |
TCMT1198 | Serratia marcescens |
TCMT1218 | Staphylococcus aureus |
TCMT1223 | Staphylococcus epidermidis |
TCMT1224 | Proteus mirabilis |
TCMT1226 | Klebsiella pneumoniae |
TCMT1227 | Streptococcus |
TCMT1229 | Enterococcus faecalis |
TCMT1232 | Pseudomonas aeruginosa |
TCMT1243 | Aspergillus flavus |
TCMT1246 | Escherichia coli |
TCMT1251 | Candida albicans |
TCMT1361 | Neisseria meningitidis |
TCMT1382 | Plasmodium falciparum (isolate K1 / Thailand) |
TCMT1412 | Salmonella typhimurium |
TCMT1442 | Leishmania donovani |
TCMT1448 | Enterobacter aerogenes |
TCMT1454 | Bacillus subtilis |
Ingredient ID: TCMC953
Formula: C4H7N3O
Ingredient ID: TCMC903
Formula: C24H40O5
Ingredient ID: TCMC885
Formula: C16H17N3O4S
Ingredient ID: TCMC78
Formula: C11H20O6
Ingredient ID: TCMC453
Formula: C9H6O3
Ingredient ID: TCMC2011
Formula: C15H12I3NO4
Ingredient ID: TCMC1997
Formula: C9H13NO3
Ingredient ID: TCMC1830
Formula: C16H32O2
Ingredient ID: TCMC1797
Formula: C5H4N2O4
Ingredient ID: TCMC1758
Formula: C8H11NO3
Ingredient ID: TCMC1753
Formula: C18H21NO3
Ingredient ID: TCMC1504
Formula: C24H40O3
Ingredient ID: TCMC1498
Formula: C15H12I3NO4
Ingredient ID: TCMC1477
Formula: C15H11I4NO4
Ingredient ID: TCMC1459
Formula: C3H7NO2
Ingredient ID: TCMC138
Formula: C21H30O4
Ingredient ID: TCMC1209
Formula: C4H9NO2
Ingredient ID | Formulae | Name | MW | AlogP | MlogP | XlogP | # HBA | # HBD | PSA | # Rotatable Bond | # Ring | # Heacy Atom | Lipinski RO5 Violation |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
TCMC78 | C11H20O6 | (2R,3S,4S,5R,6S)-2-(Hydroxymethyl)-6-(2-Methylbut-3-En-2-Yloxy)Oxane-3,4,5-Triol | 248.13 | -0.9056 | 2.01 | -0.356 | 6 | 4 | 99.38 | 10 | 1 | 17 | 0 |
TCMC138 | C21H30O4 | (8S,10R,11S,13S,14S,17S)-11-Hydroxy-17-(2-Hydroxyacetyl)-10,13-Dimethyl-1,2,6,7,8,9,11,12,14,15,16,17-Dodecahydrocyclopenta[A]Phenanthren-3-One | 346.21 | -0.5211 | 3.33 | 1.704 | 4 | 2 | 74.6 | 6 | 4 | 25 | 0 |
TCMC453 | C9H6O3 | 3-Hydroxycoumarin | 162.03 | -0.1864 | 2.12 | 3.054 | 2 | 1 | 46.53 | 1 | 2 | 12 | 0 |
TCMC885 | C16H17N3O4S | Cephalexin | 347.09 | -0.8185 | 2.34 | -1.005 | 7 | 3 | 141.52 | 8 | 3 | 24 | 0 |
TCMC903 | C24H40O5 | Cholic Acid | 408.29 | -0.4664 | 3.55 | 4.093 | 5 | 4 | 97.99 | 11 | 4 | 29 | 0 |
TCMC953 | C4H7N3O | Creatinine | 113.06 | -0.7855 | 1.46 | 0.015 | 4 | 2 | 59.68 | 2 | 1 | 8 | 0 |
TCMC1209 | C4H9NO2 | Gamma-Aminobutyric Acid | 103.06 | -1.2313 | 1.57 | -0.668 | 3 | 2 | 63.32 | 5 | 0 | 7 | 0 |
TCMC1459 | C3H7NO2 | L-Alanine | 89.05 | -1.0955 | 1.46 | -2.824 | 3 | 2 | 63.32 | 4 | 0 | 6 | 0 |
TCMC1477 | C15H11I4NO4 | Levothyroxine | 776.69 | 3.9816 | 2.12 | 2.847 | 3 | 3 | 92.78 | 12 | 2 | 24 | 0 |
TCMC1498 | C15H12I3NO4 | Liothyronine | 650.79 | 2.5615 | 2.23 | 2.213 | 3 | 3 | 92.78 | 11 | 2 | 23 | 0 |
TCMC1504 | C24H40O3 | Lithocholic Acid | 376.3 | 0.873 | 3.77 | 8.263 | 3 | 2 | 57.53 | 9 | 4 | 27 | 1 |
TCMC1753 | C18H21NO3 | Norarmepavine | 299.15 | -0.7051 | 3 | 2.755 | 1 | 2 | 50.72 | 7 | 3 | 22 | 0 |
TCMC1758 | C8H11NO3 | Norepinephrine | 169.07 | -2.1696 | 1.9 | -0.46 | 2 | 4 | 86.71 | 6 | 1 | 12 | 0 |
TCMC1797 | C5H4N2O4 | Orotic Acid | 156.02 | -1.1604 | 1.35 | -0.837 | 4 | 3 | 103.54 | 4 | 1 | 11 | 0 |
TCMC1830 | C16H32O2 | Palmitic Acid | 256.24 | -3.8977 | 3 | 7.57 | 2 | 1 | 37.3 | 16 | 0 | 18 | 2 |
TCMC1997 | C9H13NO3 | Racepinephrine | 183.09 | -1.7378 | 2.01 | -0.07 | 2 | 4 | 72.72 | 7 | 1 | 13 | 0 |
TCMC2011 | C15H12I3NO4 | Reverse Triiodothyronine | 650.79 | 2.5615 | 2.23 | 2.213 | 3 | 3 | 92.78 | 11 | 2 | 23 | 0 |