Component: Sedum sarmentosum 垂盆草清膏


Description of the Component

Component ID
TCMH313
Latin Name
Sedum sarmentosum
English Name
all - grass of stringy stonecrop
Chinese Pinyin Name
Chui Pen Cao Qing Gao
中文名
垂盆草清膏
TCM Properties
TCM Meridians
Therapeutic Class English
Therapeutic Class Chinese
Functions
Toxicity
NA
Geo-authentic habitats (道地产区)
NA
Reference
CFDA
Barcode ID
ITSAJ4288-14
Barcode Source
BOLDSYSTEMS

TCM Prescriptions with the Component

Prescription ID Prescription English Name Prescription Chinese Name
TCMFx3346 Fu Fang Chui Pen Cao Infusion 复方垂盆草冲剂

Targeted Human Proteins by the Ingredient of Component

Target ID Gene Symbol Target Name Target Class Uniprot ID
TCMT1 EHMT2 Histone-lysine N-methyltransferase, H3 lysine-9 specific 3 Transferase Q96KQ7
TCMT100 TTR Transthyretin Unclassified P02766
TCMT101 PTPN1 Protein-tyrosine phosphatase 1B Hydrolase P18031
TCMT125 GBA Beta-glucocerebrosidase Hydrolase P04062
TCMT133 CA1 Carbonic anhydrase I Lyase P00915
TCMT134 CA2 Carbonic anhydrase II Lyase P00918
TCMT136 CA12 Carbonic anhydrase XII Lyase O43570
TCMT138 CA7 Carbonic anhydrase VII Lyase P43166
TCMT142 CA4 Carbonic anhydrase IV Lyase P22748
TCMT158 EPHX2 Epoxide hydratase Lyase P34913
TCMT17 POLB DNA polymerase beta Transferase P06746
TCMT18 GAA Lysosomal alpha-glucosidase Hydrolase P10253
TCMT2 MAPT Microtubule-associated protein tau Unclassified P10636
TCMT22 ALPI Intestinal alkaline phosphatase Hydrolase P09923
TCMT223 AKR1B1 Aldose reductase Oxidoreductase P15121
TCMT23 ALPL Alkaline phosphatase, tissue-nonspecific isozyme Hydrolase P05186
TCMT254 CBR1 Carbonyl reductase [NADPH] 1 Oxidoreductase P16152
TCMT260 FLT3 Tyrosine-protein kinase receptor FLT3 Kinase P36888
TCMT27 DRD1 Dopamine D1 receptor GPCR P21728
TCMT281 DPP4 Dipeptidyl peptidase IV Unclassified P27487
TCMT3 ALOX15 Arachidonate 15-lipoxygenase Oxidoreductase P16050
TCMT307 KCNH2 HERG Ion channel Q12809
TCMT31 CYP2C19 Cytochrome P450 2C19 Oxidoreductase P33261
TCMT33 CYP3A4 Cytochrome P450 3A4 Oxidoreductase P08684
TCMT331 PLG Plasminogen Unclassified P00747
TCMT34 CYP2D6 Cytochrome P450 2D6 Oxidoreductase P10635
TCMT6 NFKB1 Nuclear factor NF-kappa-B p105 subunit Transcription factor P19838
TCMT8 KDM4E Lysine-specific demethylase 4D-like Oxidoreductase B2RXH2
TCMT80 MAPK1 MAP kinase ERK2 Kinase P28482
TCMT87 CYP2C9 Cytochrome P450 2C9 Oxidoreductase P11712
TCMT903 GRIN2B Glutamate [NMDA] receptor subunit epsilon 2 Ion channel Q13224


Targeted Pathogenic Microbes by the Ingredient of Component

Target ID Target Name
TCMT1093 Enoyl-acyl-carrier protein reductase
TCMT1099 Neuraminidase
TCMT1105 Enoyl-ACP reductase
TCMT1140 Enoyl-[acyl-carrier-protein] reductase
TCMT1142 Enoyl-[acyl-carrier-protein] reductase [NADPH]
TCMT1172 Staphylococcus aureus subsp. aureus RN4220
TCMT1174 Mycobacterium bovis BCG
TCMT1177 Haemophilus influenzae
TCMT1178 Actinomyces viscosus
TCMT1182 Streptococcus sanguinis
TCMT1211 Fusobacterium nucleatum
TCMT1212 Verticillium dahliae
TCMT1217 Bacillus anthracis
TCMT1218 Staphylococcus aureus
TCMT1223 Staphylococcus epidermidis
TCMT1224 Proteus mirabilis
TCMT1226 Klebsiella pneumoniae
TCMT1229 Enterococcus faecalis
TCMT1232 Pseudomonas aeruginosa
TCMT1246 Escherichia coli
TCMT1251 Candida albicans
TCMT1286 Bacillus cereus
TCMT1294 Human parainfluenza virus 3
TCMT1346 Helicobacter pylori
TCMT1382 Plasmodium falciparum (isolate K1 / Thailand)
TCMT1438 Plasmodium falciparum
TCMT1443 Leishmania amazonensis
TCMT1447 Respiratory syncytial virus
TCMT1450 Plasmodium falciparum 3D7
TCMT1454 Bacillus subtilis
TCMT1455 Mycobacterium tuberculosis H37Rv
TCMT1458 Filobasidiella neoformans
TCMT1462 Streptococcus mutans
TCMT1463 Mycobacterium tuberculosis
TCMT1465 Entamoeba histolytica

Ingredient Structrues

Ingredient ID: TCMC2594
Formula: C6H13NO2

Ingredient ID: TCMC2408
Formula: C5H11NO2

Ingredient ID: TCMC2189
Formula: C12H7Cl3O2

Ingredient ID: TCMC178
Formula: C15H12O4

Ingredient ID: TCMC1459
Formula: C3H7NO2

Ingredient ID: TCMC1409
Formula: C21H20O12

Ingredient ID: TCMC1400
Formula: C21H22O9

Ingredient ID: TCMC1365
Formula: C21H27NO2

Ingredient ID: TCMC1206
Formula: C21H20O11

Properties

Ingredient ID Formulae Name MW AlogP MlogP XlogP # HBA # HBD PSA # Rotatable Bond # Ring # Heacy Atom Lipinski RO5 Violation
TCMC178 C15H12O4 (Z)-1-(2,4-Dihydroxyphenyl)-3-(4-Hydroxyphenyl)Prop-2-En-1-One 256.07 -1.2836 2.67 2.764 1 3 77.76 6 2 19 0
TCMC1206 C21H20O11 Galuteolin 448.1 -4.0917 2.56 -0.075 6 7 186.37 11 4 32 1
TCMC1365 C21H27NO2 Ifenprodil 325.2 -1.4946 3.44 6.011 2 2 43.7 8 3 24 1
TCMC1400 C21H22O9 Isoliquiritin 418.13 -3.0305 2.78 1.656 6 6 156.91 12 3 30 1
TCMC1409 C21H20O12 Isoquercetin 464.1 -4.8921 2.45 -0.354 7 8 206.6 12 4 33 1
TCMC1459 C3H7NO2 L-Alanine 89.05 -1.0955 1.46 -2.824 3 2 63.32 4 0 6 0
TCMC2189 C12H7Cl3O2 Triclosan 287.95 1.6185 2.23 4.009 0 1 29.46 6 2 17 0
TCMC2408 C5H11NO2 Valine 117.08 -0.5739 1.68 -2.169 3 2 63.32 6 0 8 0
TCMC2594 C6H13NO2 Leucine 131.09 -0.3183 1.79 -1.389 3 2 63.32 7 0 9 0

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