Targeted Human Proteins by the Ingredients of Prescription

References are linked to referred publications via PubMed ID or DOI.
There may be multiple activity records for a specific ingredient-target pair.
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Ingredient ID & Structure	Target ID	Target Name	Target Organism	Activity Records & Reference
TCMC1409	TCMT22	Intestinal alkaline phosphatase	Homo sapiens	IC50: 5250 (nM), Ref: IC50: 8960 (nM), Ref:
TCMC1409	TCMT223	Aldose reductase	Homo sapiens	IC50: 4500 (nM), Ref: 22261024
TCMC1409	TCMT134	Carbonic anhydrase II	Homo sapiens	Ki: 6211.2 (nM), Ref: 26498393 Ki: 410 (nM), Ref: 26498393
TCMC1409	TCMT142	Carbonic anhydrase IV	Homo sapiens	Ki: 75.7 (nM), Ref: 26498393
TCMC1409	TCMT138	Carbonic anhydrase VII	Homo sapiens	Ki: 3.8 (nM), Ref: 26498393
TCMC1409	TCMT136	Carbonic anhydrase XII	Homo sapiens	Ki: 52.1 (nM), Ref: 26498393 Ki: 170 (nM), Ref: 26498393
TCMC2189	TCMT254	Carbonyl reductase [NADPH] 1	Homo sapiens	IC50: 400 (nM), Ref: 19097799 Ki: 60 (nM), Ref: 19097799
TCMC1400	TCMT223	Aldose reductase	Homo sapiens	IC50: 720 (nM), Ref: 22261024
TCMC1365	TCMT307	HERG	Homo sapiens	IC50: 100 (nM), Ref: 21185626
TCMC1365	TCMT903	Glutamate [NMDA] receptor subunit epsilon 2	Homo sapiens	IC50: 20 (nM), Ref: 24411196 Ki: 10 (nM), Ref: 25458498

Targeted Pathogenic Microbes or non-Human Proteins by the Ingredients of Prescription

References are linked to referred publications via PubMed ID or DOI.
There may be multiple activity records for a specific ingredient-target pair.

Ingredient ID & Structure	Target ID	Target Name	Target Organism	Activity Records & Reference
TCMC1206	TCMT1099	Neuraminidase	Influenza A virus (A/Puerto Rico/8/1934(H1N1))	IC50: 21.25 (ug/ml), Ref: 20116898
TCMC2189	TCMT1093	Enoyl-acyl-carrier protein reductase	Plasmodium falciparum	IC50: 0.014 (ug/ml), Ref: 17765547 IC50: 73 (nM), Ref: 16198563 IC50: 73 (nM), Ref: 16466916 Ki: 7.29 (nM), Ref: 17263522 Ki: 28.31 (nM), Ref: 17263522 Ki: 52.71 (nM), Ref: 17263522 Ki: 30.54 (nM), Ref: 17263522 Ki: 71.02 (nM), Ref: 17263522 Ki: 0.0019 (nM), Ref: 17263522 Ki: 0.109 (nM), Ref: 17263522 Ki: 0.05206 (nM), Ref: 17263522 Ki: 0.2806 (nM), Ref: 17263522 Ki: 0.7983 (nM), Ref: 17263522 Ki: 1 (nM), Ref: 17263522 Ki: 8.25 (nM), Ref: 17263522 Ki: 8 (nM), Ref: 17263522 Ki: 10 (nM), Ref: 17263522 Ki: 13.72 (nM), Ref: 17263522 IC50: 66 (nM), Ref: 17477517 IC50: 73 (nM), Ref: 17567585 IC50: 70 (nM), Ref: 17485508 IC50: 73 (nM), Ref: 19217192 Ki: 50 (nM), Ref: 19217192 IC50: 70 (nM), Ref: 22082562
TCMC2189	TCMT1105	Enoyl-ACP reductase	Plasmodium falciparum	IC50: 0.014 (ug/ml), Ref: 20855214
TCMC1409	TCMT1463	Mycobacterium tuberculosis	Mycobacterium tuberculosis H37Rv	MIC: 94 (ug/ml), Ref: 15104489
TCMC1409	TCMT1447	Respiratory syncytial virus	Respiratory syncytial virus	IC50: 5.9 (ug/ml), Ref: 15104496
TCMC1409	TCMT1294	Human parainfluenza virus 3	Human parainfluenza virus 3	IC50: 23.4 (ug/ml), Ref: 15104496
TCMC1409	TCMT1346	Helicobacter pylori	Helicobacter pylori	MIC: 25 (ug/ml), Ref: 12762812
TCMC1409	TCMT1443	Leishmania amazonensis	Leishmania amazonensis	IC50: 0.78 (ug/ml), Ref: 10.1039/C5MD00481K
TCMC1206	TCMT1465	Entamoeba histolytica	Entamoeba histolytica	IC50: 44.7 (ug/ml), Ref: 10.1007/s00044-011-9767-1
TCMC2189	TCMT1246	Escherichia coli	Escherichia coli	MIC: 0.3 (ug/ml), Ref: 14736233 MIC: 0.2 (ug/ml), Ref: 19933806 MIC: 3 (ug/ml), Ref: 19933806 MIC: 4 (ug/ml), Ref: 19933806 MIC: 0.2 (ug/ml), Ref: 18180352 MIC: 0.125 (ug/ml), Ref: 23092194 MIC: 2 (ug/ml), Ref: 23466234
TCMC2189	TCMT1218	Staphylococcus aureus	Staphylococcus aureus	MIC: 0.06 (ug/ml), Ref: 12109908 MIC: 0.03 (ug/ml), Ref: 11514139 MIC: 0.125 (ug/ml), Ref: 17095231 MIC: 0.063 (ug/ml), Ref: 17713898 MIC: 20 (ug/ml), Ref: 21821415 MIC: 0.031 (ug/ml), Ref: 23092194 MIC: 4 (ug/ml), Ref: 23466234 MIC: 0.01 (ug/ml), Ref: 24332629 MIC: 0.391 (ug/ml), Ref: 26343826
TCMC2189	TCMT1177	Haemophilus influenzae	Haemophilus influenzae	MIC: 0.06 (ug/ml), Ref: 12109908
TCMC2189	TCMT1462	Streptococcus mutans	Streptococcus mutans	MIC: 16 (ug/ml), Ref: 17220400 MIC: 4 (ug/ml), Ref: 20427099
TCMC2189	TCMT1217	Bacillus anthracis	Bacillus anthracis	MIC: 3.1 (ug/ml), Ref: 18499454
TCMC2189	TCMT1463	Mycobacterium tuberculosis	Mycobacterium tuberculosis H37Rv	MIC: 5 (ug/ml), Ref: 18538450 MIC: 5 (ug/ml), Ref: 22079026
TCMC2189	TCMT1178	Actinomyces viscosus	Actinomyces viscosus	MIC: 4 (ug/ml), Ref: 20427099
TCMC2189	TCMT1182	Streptococcus sanguinis	Streptococcus sanguinis	MIC: 4 (ug/ml), Ref: 20427099
TCMC2189	TCMT1211	Fusobacterium nucleatum	Fusobacterium nucleatum	MIC: 2 (ug/ml), Ref: 20427099
TCMC2189	TCMT1232	Pseudomonas aeruginosa	Pseudomonas aeruginosa	MIC: 1 (ug/ml), Ref: 19933806
TCMC2189	TCMT1224	Proteus mirabilis	Proteus mirabilis	MIC: 0.2 (ug/ml), Ref: 18180352 MIC: 40 (ug/ml), Ref: 18180352 MIC: 2 (ug/ml), Ref: 18180352 MIC: 5 (ug/ml), Ref: 18180352 MIC: 0.1 (ug/ml), Ref: 18180352 MIC: 20 (ug/ml), Ref: 18180352 MIC: 10 (ug/ml), Ref: 18180352 MIC: 0.8 (ug/ml), Ref: 18180352
TCMC2189	TCMT1174	Mycobacterium bovis BCG	Mycobacterium bovis BCG	MIC: 8 (ug/ml), Ref: 19564371
TCMC2189	TCMT1463	Mycobacterium tuberculosis	Mycobacterium tuberculosis	MIC: 5 (ug/ml), Ref: 18538450 MIC: 5 (ug/ml), Ref: 22079026
TCMC2189	TCMT1229	Enterococcus faecalis	Enterococcus faecalis	MIC: 2 (ug/ml), Ref: 23092194
TCMC2189	TCMT1455	Mycobacterium tuberculosis H37Rv	Mycobacterium tuberculosis H37Rv	MIC: 10 (ug/ml), Ref: 24292339 MIC: 10 (ug/ml), Ref: 25771110
TCMC2189	TCMT1286	Bacillus cereus	Bacillus cereus	MIC: 0.01 (ug/ml), Ref: 24332629
TCMC2189	TCMT1172	Staphylococcus aureus subsp. aureus RN4220	Staphylococcus aureus subsp. aureus RN4220	MIC: 0.01 (ug/ml), Ref: 24332629
TCMC2189	TCMT1140	Enoyl-[acyl-carrier-protein] reductase	Staphylococcus aureus	IC50: 70 (nM), Ref: 12699381
TCMC2189	TCMT1142	Enoyl-[acyl-carrier-protein] reductase [NADPH]	Staphylococcus aureus	IC50: 59 (nM), Ref: 23092194