Component: Bubalus bubalis 水牛角

Description of the Component

Component ID
Latin Name
Bubalus bubalis
English Name
Buffalo horn
Chinese Pinyin Name
Shui Niu Jiao
TCM Properties
TCM Meridians
Therapeutic Class English
Heat clearence
Therapeutic Class Chinese
remove toxic heat, reducing heat in blood, and arrest convulsions
Geo-authentic habitats (道地产区)
Chinese Pharmacopoeia (2015)
Barcode ID
Barcode Source

TCM Prescriptions with the Component

Prescription ID Prescription English Name Prescription Chinese Name
TCMF2936 An Gong Jiang Ya Pills 安宫降压丸
TCMFx2915 An Gong Niu Huang Tablets 安宫牛黄片
TCMF2940 An Nao Niu Huang Tablets 安脑牛黄片
TCMFx2927 An Nao Pills 安脑丸
TCMFx2916 An Nao Tablets 安脑片
TCMFx2935 An Ning Bao Ying Powder 安宁保婴散
TCMFx2958 Ba Bao Wu Dan Yao Mo 八宝五胆药墨
TCMFx2321 Bolus of Calculus Bovis for Resurrection 安宫牛黄丸
TCMFx1371 Bolus of Calculus Bovis for Resurrection 安宫牛黄丸
TCMF3917 Chai Huang Qing Re Infusion 柴黄清热冲剂
TCMFx3965 Chan She Jiu Xin Pills 蟾麝救心丸
TCMF3893 Er Tong Hui Chun Granules 儿童回春颗粒
TCMF3901 Er Tong Hui Chun Pills 儿童回春丸
TCMFx3644 Fo Shan Ren Shen Zai Zao Pills 佛山人参再造丸
TCMFx3635 Fo Shan Ren Shen Zai Zao Tablets 佛山人参再造片
TCMF3952 Fu Fang Shi Hu Tablets 复方石斛片
TCMF3135 Fu Fang Xi Ling Jie Du Pills 复方西羚解毒丸
TCMFx3127 Fu Fang Xi Ling Jie Du Tablets 复方西羚解毒片
TCMF3363 Fu Fang Zhen Zhu An Chuang Tablets 复方珍珠暗疮片
TCMFx3654 Gua Shuang Tui Re Ling Capsules 瓜霜退热灵胶囊
TCMFx4558 Hou Tong Ling Tablets 喉痛灵片
TCMFx4573 Hou Tong Pills 喉痛丸
TCMFx4592 Hou Yan Pills 喉炎丸
TCMF4733 Hu Po Huan Qing Pills 琥珀还晴丸
TCMF4888 Hua Du Dan 化毒丹
TCMFx4264 Hui Sheng Zai Zao Pills 回生再造丸
TCMFx4325 Huo Luo Pills 活络丸
TCMFx4782 Jie Re Xiao Yan Capsules 解热消炎胶囊
TCMFx4961 Jin Ju Gan Mao Tablets 金菊感冒片
TCMFx4016 Jin Ling Gan Mao Tablets 金羚感冒片
TCMFx4624 Jiu Xin Jin Pills 救心金丸
TCMFx4638 Ju Fang Zhi Bao Pills 局方至宝丸
TCMFx4679 Ju Lan Kang Liu Gan Tablets 菊蓝抗流感片
TCMF4169 Kang Re Zhen Jing Pills 抗热镇痉丸
TCMFx4416 Ling Yang Qing Fei Powder 羚羊清肺散
TCMFx4443 Ling Zhu Powder 羚竺散
TCMFx4965 Lv Xue 绿雪
TCMFx4973 Lv Xue Capsules 绿雪胶囊
TCMF4450 Miao Ling Pills 妙灵丸
TCMFx4979 Niu Huang Ba Bao Pills 牛黄八宝丸
TCMFx4194 Niu Huang Qing Fei Powder 牛黄清肺散
TCMFx4213 Niu Huang Qing Nao Pills 牛黄清脑丸
TCMFx4221 Niu Huang Qing Re Capsules 牛黄清热胶囊
TCMFx4227 Niu Huang Qing Re Powder 牛黄清热散
TCMF4258 Niu Huang Xi Ling Pills 牛黄西羚丸
TCMFx4266 Niu Huang Xiao Yan Ling Capsules 牛黄消炎灵胶囊
TCMFx4273 Niu Huang Xiao Yan Ling Pills 牛黄消炎灵丸
TCMFx4293 Niu Huang Xing Nao Pills 牛黄醒脑丸
TCMFx4340 Nong Suo Shui Niu Jiao Tablets 浓缩水牛角片
TCMF5231 Qing Ge Pills 清膈丸
TCMF5274 Qing Huo Jie Du Pills 清火解毒丸
TCMFx1081 Qing Kai Ling Capsule 清开灵胶囊
TCMFx7045 Qing Kai Ling Di Pills 清开灵滴丸
TCMFx6863 Qing Kai Ling Fen San Tablets 清开灵分散片
TCMFx72 Qing Kai Ling Granules 清开灵颗粒
TCMFx1080 Qing Kai Ling Injection 清开灵注射液
TCMFx1077 Qing Kai Ling Oral Liquid 清开灵口服液
TCMFx1079 Qing Kai Ling Pao Teng Tablet 清开灵泡腾片
TCMFx71 Qing Kai Ling Ruan Capsule 清开灵软胶囊
TCMFx1078 Qing Kai Ling Tablet 清开灵片
TCMFx5357 Qing Kai Ling Zhu She Oral Liquid 清开灵注射液
TCMF5540 Qing Re Jie Du Granules 清热解毒颗粒
TCMFx5667 Qing Re Xing Nao Ling Pills 清热醒脑灵丸
TCMFx5698 Qing Re Zhen Jing Powder 清热镇惊散
TCMF5127 Qing Shen Jian Fei Tablets 轻身减肥片
TCMFx5806 Qing Xin Gun Tan Pills 清心滚痰丸
TCMFx5831 Qing Xin Niu Huang Tablets 清心牛黄片
TCMFx5840 Qing Xin Pills 清心丸
TCMFx5864 Qing Xuan Zhi Tan Pills 清眩治瘫丸
TCMF4958 Qing Yan Run Hou Pills 清咽润喉丸
TCMFx5006 Qing Yu Bi Wen Dan 庆余辟瘟丹
TCMF5069 Qu Feng Su He Pills 驱风苏合丸
TCMFx5537 Ren Shen Zai Zao Pills 人参再造丸
TCMFx5553 Ren Shen Zhi Bao Pills 人参至宝丸
TCMF5415 Shen Xi Dan 神犀丹
TCMF5423 Shen Xiang Su He Pills 神香苏合丸
TCMF5108 Shi Hu Ming Mu Pills 石斛明目丸
TCMF5153 Shi Yi Qing Wen Pills 时疫清瘟丸
TCMF5756 Shui Niu Jiao Jie Du Pills 水牛角解毒丸
TCMFx5082 Su Xiao Niu Huang Pills 速效牛黄丸
TCMFx5825 Tong Luo Huo Xue Pills 通络活血丸
TCMFx5051 Tong Ren Da Huo Luo Pills 同仁大活络丸
TCMFx5057 Tong Ren Niu Huang Qing Xin Pills 同仁牛黄清心丸
TCMFx2139 Treasured Bolus 居方至宝散
TCMFx5529 Wei Sheng Bao Pills 卫生宝丸
TCMF5483 Wu Li Hui Chun Pills 五粒回春丸
TCMF5750 Xi Jiao Hua Du Pills 犀角化毒丸
TCMF5707 Xi Ling Dan 西羚丹
TCMF5758 Xi Ling Jie Du Pills 犀羚解毒丸
TCMF5716 Xi Ling Tablets 西羚片
TCMF5962 Xian Zheng Zhen Xin Pills 痫症镇心丸
TCMFx6552 Xiao Er Bai Le Tablets 小儿百乐片
TCMFx6572 Xiao Er Bai Xiao Tablets 小儿百效片
TCMF5981 Xiao Er Jin Dan 小儿金丹
TCMF5989 Xiao Er Jin Dan Tablets 小儿金丹片
TCMFx6111 Xiao Er Ling Yang Powder 小儿羚羊散
TCMFx6159 Xiao Er Niu Huang Qing Xin Powder 小儿牛黄清心散
TCMFx6205 Xiao Er Qi Zhen Pills 小儿七珍丸
TCMFx6285 Xiao Er Qing Re Hua Tan Shuan 小儿清热化痰栓
TCMFx6297 Xiao Er Qing Re Ning Granules 小儿清热宁颗粒
TCMF270 Xiao Er Re Su Qing Granules 小儿热速清颗粒
TCMF269 Xiao Er Re Su Qing Oral Liquid 小儿热速清口服液
TCMF271 Xiao Er Re Su Qing Syrup 小儿热速清糖浆
TCMF6339 Xiao Er Shu Biao Pills 小儿疏表丸
TCMFx6354 Xiao Tong Tie Ointment 消痛贴膏
TCMF6044 Xin Fang Bi Yan Capsules 辛芳鼻炎胶囊
TCMFx6090 Xin Huang Tablets 新癀片
TCMFx6781 Xin Ke Ning Capsules 心可宁胶囊
TCMFx6161 Xing Nao Niu Huang Qing Xin Tablets 醒脑牛黄清心片
TCMFx6270 Xiong Dan Jiu Xin Dan 熊胆救心丹
TCMF6458 Xue Bao Capsules 血宝胶囊
TCMFx6105 Zhen Huang An Gong Tablets 珍黄安宫片
TCMFx6224 Zhong Feng Zai Zao Pills 中风再造丸

Targeted Human Proteins by the Ingredient of Component

Target ID Gene Symbol Target Name Target Class Uniprot ID
TCMT1 EHMT2 Histone-lysine N-methyltransferase, H3 lysine-9 specific 3 Transferase Q96KQ7
TCMT105 SLC15A2 Solute carrier family 15 member 2 Transporter Q16348
TCMT11 HIF1A Hypoxia-inducible factor 1 alpha Transcription factor Q16665
TCMT125 GBA Beta-glucocerebrosidase Hydrolase P04062
TCMT13 APEX1 DNA-(apurinic or apyrimidinic site) lyase Lyase P27695
TCMT150 RORC Nuclear receptor ROR-gamma Nuclear receptor P51449
TCMT156 CYP19A1 Cytochrome P450 19A1 Oxidoreductase P11511
TCMT162 UGT1A1 UDP-glucuronosyltransferase 1-1 Transferase P22309
TCMT175 GPBAR1 G-protein coupled bile acid receptor 1 GPCR Q8TDU6
TCMT187 AR Androgen Receptor Nuclear receptor P10275
TCMT2 MAPT Microtubule-associated protein tau Unclassified P10636
TCMT213 SLC22A1 Solute carrier family 22 member 1 Transporter O15245
TCMT223 AKR1B1 Aldose reductase Oxidoreductase P15121
TCMT243 ADRA2C Alpha-2c adrenergic receptor GPCR P18825
TCMT247 ADRA2A Alpha-2a adrenergic receptor GPCR P08913
TCMT248 CXCL8 Interleukin-8 Unclassified P10145
TCMT267 GABRR1 GABA receptor rho-1 subunit Ion channel P24046
TCMT27 DRD1 Dopamine D1 receptor GPCR P21728
TCMT273 NR1H4 Bile acid receptor FXR Nuclear receptor Q96RI1
TCMT276 SLCO2B1 Solute carrier organic anion transporter family member 2B1 Transporter O94956
TCMT277 SLCO1B3 Solute carrier organic anion transporter family member 1B3 Transporter Q9NPD5
TCMT278 SLCO1B1 Solute carrier organic anion transporter family member 1B1 Transporter Q9Y6L6
TCMT279 VDR Vitamin D receptor Nuclear receptor P11473
TCMT297 FABP4 Fatty acid binding protein adipocyte Unclassified P15090
TCMT298 FABP3 Fatty acid binding protein muscle Hydrolase P05413
TCMT33 CYP3A4 Cytochrome P450 3A4 Oxidoreductase P08684
TCMT341 NR1I2 Pregnane X receptor Nuclear receptor O75469
TCMT38 DRD2 Dopamine D2 receptor GPCR P14416
TCMT42 KMT2A Histone-lysine N-methyltransferase MLL Transferase Q03164
TCMT559 ADRB2 Beta-2 adrenergic receptor GPCR P07550
TCMT588 DAO D-amino-acid oxidase Oxidoreductase P14920
TCMT6 NFKB1 Nuclear factor NF-kappa-B p105 subunit Transcription factor P19838
TCMT63 PPARA Peroxisome proliferator-activated receptor alpha Nuclear receptor Q07869
TCMT64 PPARD Peroxisome proliferator-activated receptor delta Nuclear receptor Q03181
TCMT643 ADRA1A Alpha-1a adrenergic receptor GPCR P35348
TCMT647 ADRA2B Alpha-2b adrenergic receptor GPCR P18089
TCMT650 ADRA1B Alpha-1b adrenergic receptor GPCR P35368
TCMT67 PPARG Peroxisome proliferator-activated receptor gamma Nuclear receptor P37231
TCMT69 THRB Thyroid hormone receptor beta-1 Nuclear receptor P10828
TCMT737 APOBEC3G DNA dC->dU-editing enzyme APOBEC-3G Unclassified Q9HC16
TCMT796 PCNA Proliferating cell nuclear antigen Unclassified P12004
TCMT80 MAPK1 MAP kinase ERK2 Kinase P28482
TCMT808 FABP5 Fatty acid binding protein epidermal Unclassified Q01469
TCMT809 FABP2 Fatty acid binding protein intestinal Unclassified P12104
TCMT810 TLR2 Toll-like receptor 2 Unclassified O60603
TCMT864 THRA Thyroid hormone receptor alpha Nuclear receptor P10827

Targeted Pathogenic Microbes by the Ingredient of Component

Target ID Target Name
TCMT1170 Enterobacter cloacae
TCMT1176 Streptococcus pneumoniae
TCMT1177 Haemophilus influenzae
TCMT1193 Staphylococcus
TCMT1194 Shigella sonnei
TCMT1195 Streptococcus pasteurianus
TCMT1196 Salmonella
TCMT1197 Shigella sp.
TCMT1198 Serratia marcescens
TCMT1218 Staphylococcus aureus
TCMT1223 Staphylococcus epidermidis
TCMT1224 Proteus mirabilis
TCMT1226 Klebsiella pneumoniae
TCMT1227 Streptococcus
TCMT1229 Enterococcus faecalis
TCMT1232 Pseudomonas aeruginosa
TCMT1243 Aspergillus flavus
TCMT1246 Escherichia coli
TCMT1251 Candida albicans
TCMT1361 Neisseria meningitidis
TCMT1382 Plasmodium falciparum (isolate K1 / Thailand)
TCMT1412 Salmonella typhimurium
TCMT1442 Leishmania donovani
TCMT1448 Enterobacter aerogenes
TCMT1454 Bacillus subtilis

Ingredient Structrues

Ingredient ID: TCMC953
Formula: C4H7N3O

Ingredient ID: TCMC903
Formula: C24H40O5

Ingredient ID: TCMC885
Formula: C16H17N3O4S

Ingredient ID: TCMC78
Formula: C11H20O6

Ingredient ID: TCMC453
Formula: C9H6O3

Ingredient ID: TCMC2011
Formula: C15H12I3NO4

Ingredient ID: TCMC1997
Formula: C9H13NO3

Ingredient ID: TCMC1830
Formula: C16H32O2

Ingredient ID: TCMC1797
Formula: C5H4N2O4

Ingredient ID: TCMC1758
Formula: C8H11NO3

Ingredient ID: TCMC1753
Formula: C18H21NO3

Ingredient ID: TCMC1504
Formula: C24H40O3

Ingredient ID: TCMC1498
Formula: C15H12I3NO4

Ingredient ID: TCMC1477
Formula: C15H11I4NO4

Ingredient ID: TCMC1459
Formula: C3H7NO2

Ingredient ID: TCMC138
Formula: C21H30O4

Ingredient ID: TCMC1209
Formula: C4H9NO2


Ingredient ID Formulae Name MW AlogP MlogP XlogP # HBA # HBD PSA # Rotatable Bond # Ring # Heacy Atom Lipinski RO5 Violation
TCMC78 C11H20O6 (2R,3S,4S,5R,6S)-2-(Hydroxymethyl)-6-(2-Methylbut-3-En-2-Yloxy)Oxane-3,4,5-Triol 248.13 -0.9056 2.01 -0.356 6 4 99.38 10 1 17 0
TCMC138 C21H30O4 (8S,10R,11S,13S,14S,17S)-11-Hydroxy-17-(2-Hydroxyacetyl)-10,13-Dimethyl-1,2,6,7,8,9,11,12,14,15,16,17-Dodecahydrocyclopenta[A]Phenanthren-3-One 346.21 -0.5211 3.33 1.704 4 2 74.6 6 4 25 0
TCMC453 C9H6O3 3-Hydroxycoumarin 162.03 -0.1864 2.12 3.054 2 1 46.53 1 2 12 0
TCMC885 C16H17N3O4S Cephalexin 347.09 -0.8185 2.34 -1.005 7 3 141.52 8 3 24 0
TCMC903 C24H40O5 Cholic Acid 408.29 -0.4664 3.55 4.093 5 4 97.99 11 4 29 0
TCMC953 C4H7N3O Creatinine 113.06 -0.7855 1.46 0.015 4 2 59.68 2 1 8 0
TCMC1209 C4H9NO2 Gamma-Aminobutyric Acid 103.06 -1.2313 1.57 -0.668 3 2 63.32 5 0 7 0
TCMC1459 C3H7NO2 L-Alanine 89.05 -1.0955 1.46 -2.824 3 2 63.32 4 0 6 0
TCMC1477 C15H11I4NO4 Levothyroxine 776.69 3.9816 2.12 2.847 3 3 92.78 12 2 24 0
TCMC1498 C15H12I3NO4 Liothyronine 650.79 2.5615 2.23 2.213 3 3 92.78 11 2 23 0
TCMC1504 C24H40O3 Lithocholic Acid 376.3 0.873 3.77 8.263 3 2 57.53 9 4 27 1
TCMC1753 C18H21NO3 Norarmepavine 299.15 -0.7051 3 2.755 1 2 50.72 7 3 22 0
TCMC1758 C8H11NO3 Norepinephrine 169.07 -2.1696 1.9 -0.46 2 4 86.71 6 1 12 0
TCMC1797 C5H4N2O4 Orotic Acid 156.02 -1.1604 1.35 -0.837 4 3 103.54 4 1 11 0
TCMC1830 C16H32O2 Palmitic Acid 256.24 -3.8977 3 7.57 2 1 37.3 16 0 18 2
TCMC1997 C9H13NO3 Racepinephrine 183.09 -1.7378 2.01 -0.07 2 4 72.72 7 1 13 0
TCMC2011 C15H12I3NO4 Reverse Triiodothyronine 650.79 2.5615 2.23 2.213 3 3 92.78 11 2 23 0

Download Data

All data can be downloaded by:

   → Selecting data type in the below download table
   → Then click the download button.
Data Section
Select to Download
1. General Information of the Component  
2. TCM Prescriptions with the Component  
3. Putative Targets  
4. Activity & References for Filtering Putative Targets  
5. Ingredient Data & Chemical Structure Information (Properties, InChI, InChIkey, SMILES, etc.)