| GO Term |
GO Name |
Enriched Genes |
Log10 Adjusted P-value |
|
[BP] GO:0065008 |
regulation of biological quality
|
ABCB1, ACHE, ADORA1, ADRA2A, ADRA2C, ADRB1, AKR1B1, ALOX15, APEX1, AURKB, AXL, CA12, CA2, CA7, CACNA1C, CDK6, CYP19A1, CYP1A1, CYP1B1, EGFR, F10, FABP3, FABP4, FLT3, GPR35, HSD11B1, HSD17B1, HSD17B2, HSPA1A, INSR, KDR, KIT, MET, NR1H4, POLA1, POLB, PPARA, PTAFR, SMAD3, SRC, TEK, THRA, THRB, TNKS, TNKS2, XDH |
11.4315 |
|
[BP] GO:0010647 |
positive regulation of cell communication
|
ADORA1, ADRA2A, ADRA2C, ADRB1, AKR1B1, ALOX15, AXL, CA2, CA7, CSNK2A1, CYP19A1, CYP1B1, EGFR, ERBB2, F10, FLT3, GPR35, HSPA1A, INSR, KDR, KIT, MET, MMP12, MMP9, NR1H4, PTPN1, SMAD3, SRC, TEK, TNKS, TNKS2, XDH |
10.1256 |
|
[BP] GO:0023056 |
positive regulation of signaling
|
ADORA1, ADRA2A, ADRA2C, ADRB1, AKR1B1, ALOX15, AXL, CA2, CA7, CSNK2A1, CYP19A1, CYP1B1, EGFR, ERBB2, F10, FLT3, GPR35, HSPA1A, INSR, KDR, KIT, MET, MMP12, MMP9, NR1H4, PTPN1, SMAD3, SRC, TEK, TNKS, TNKS2, XDH |
10.1256 |
|
[BP] GO:0008152 |
metabolic process
|
ACHE, ADORA1, ADRB1, AKR1B1, AKR1B10, ALOX15, ALOX5, APEX1, AURKB, AXL, CA1, CA12, CA2, CA4, CA7, CA9, CBR1, CDC25B, CDK6, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, DAO, DUSP3, EGFR, ERBB2, F10, FABP3, FABP4, FLT3, GLO1, HSD11B1, HSD17B1, HSD17B2, HSPA1A, IGF1R, INSR, KDR, KIT, MET, MMP1, MMP12, MMP2, MMP9, NR1H4, NUAK1, PHF8, PIM1, POLA1, POLB, PPARA, PTAFR, PTPN1, PTPRS, RORC, SMAD3, SRC, TBXAS1, TEK, THRA, THRB, TNKS, TNKS2, TOP1, TOP2A, TYR, XDH |
8.89405 |
|
[BP] GO:0010033 |
response to organic substance
|
ADRA2A, AKR1B1, ALOX15, APEX1, AXL, CA2, CA9, CDK6, CSNK2A1, CYP1A1, CYP1A2, CYP1B1, EGFR, ERBB2, FABP3, FABP4, FLT3, HSD17B2, HSPA1A, IGF1R, INSR, KDR, KIT, MMP2, NR1H4, POLB, PPARA, PTAFR, RORC, SMAD3, SRC, TEK, TYR |
8.88862 |
|
[BP] GO:0009967 |
positive regulation of signal transduction
|
ADORA1, ADRA2A, ADRA2C, ADRB1, AKR1B1, ALOX15, AXL, CSNK2A1, CYP1B1, EGFR, ERBB2, F10, FLT3, GPR35, HSPA1A, INSR, KDR, KIT, MET, MMP12, MMP9, NR1H4, PTPN1, SMAD3, SRC, TEK, TNKS, TNKS2, XDH |
8.84411 |
|
[BP] GO:0048522 |
positive regulation of cellular process
|
ACHE, ADORA1, ADRA2A, ADRA2C, ADRB1, AKR1B1, ALOX15, APEX1, AURKB, AXL, CA2, CA7, CDC25B, CDK6, CSNK2A1, CYP19A1, CYP1A1, CYP1B1, DUSP3, EGFR, ERBB2, F10, FABP3, FLT3, GPR35, HSPA1A, IGF1R, INSR, KDR, KIT, MET, MMP1, MMP12, MMP2, MMP9, NR1H4, PHF8, PIM1, PPARA, PTAFR, PTPN1, RORC, SMAD3, SRC, TEK, THRA, THRB, TNKS, TNKS2, TOP2A, XDH |
8.74107 |
|
[BP] GO:0006629 |
lipid metabolic process
|
ACHE, ADORA1, AKR1B1, AKR1B10, ALOX15, ALOX5, CBR1, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, EGFR, ERBB2, FABP3, FABP4, HSD11B1, HSD17B1, HSD17B2, KIT, MET, NR1H4, PPARA, TBXAS1 |
8.74107 |
|
[BP] GO:0042221 |
response to chemical
|
ABCB1, ADRA2A, AKR1B1, ALOX15, APEX1, AXL, CA2, CA9, CDK6, CSNK2A1, CYP1A1, CYP1A2, CYP1B1, EGFR, ERBB2, FABP3, FABP4, FLT3, HSD17B2, HSPA1A, IGF1R, INSR, KDR, KIT, MMP2, MMP9, NR1H4, POLB, PPARA, PTAFR, RORC, SMAD3, SRC, TEK, TOP1, TYR |
8.65865 |
|
[BP] GO:0048513 |
animal organ development
|
ACHE, AXL, CA2, CACNA1C, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, EGFR, ERBB2, FLT3, HSD11B1, HSD17B2, INSR, KDR, KIT, PHF8, POLB, PPARA, PTPRS, SMAD3, SRC, TEK, THRA, TYR |
8.09548 |
|
[BP] GO:0048518 |
positive regulation of biological process
|
ABCB1, ACHE, ADORA1, ADRA2A, ADRA2C, ADRB1, AKR1B1, ALOX15, APEX1, AURKB, AXL, CA2, CA7, CDC25B, CDK6, CSNK2A1, CYP19A1, CYP1A1, CYP1B1, DUSP3, EGFR, ERBB2, F10, FABP3, FABP4, FLT3, GPR35, HSPA1A, IGF1R, INSR, KDR, KIT, MET, MMP1, MMP12, MMP2, MMP9, NR1H4, PHF8, PIM1, PPARA, PTAFR, PTPN1, RORC, SMAD3, SRC, TEK, THRA, THRB, TNKS, TNKS2, TOP2A, XDH |
7.99791 |
|
[BP] GO:0032879 |
regulation of localization
|
ABCB1, ACHE, ADORA1, ADORA3, ADRA2A, ADRA2C, ALOX15, APEX1, AXL, CA2, CA7, CACNA1C, CDK6, CSNK2A1, CYP19A1, CYP1B1, EGFR, ERBB2, F10, GPR35, HSPA1A, IGF1R, INSR, KDR, KIT, MET, MMP12, MMP9, NR1H4, PPARA, PTAFR, PTPN1, SMAD3, SRC, TEK, THRA |
7.96025 |
|
[BP] GO:0044237 |
cellular metabolic process
|
ACHE, AKR1B1, AKR1B10, ALOX15, ALOX5, APEX1, AURKB, AXL, CA1, CA12, CA2, CA4, CA7, CA9, CBR1, CDC25B, CDK6, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, DAO, DUSP3, EGFR, ERBB2, F10, FABP3, FABP4, FLT3, GLO1, HSD17B1, HSD17B2, HSPA1A, IGF1R, INSR, KDR, KIT, MET, MMP1, MMP2, NR1H4, NUAK1, PHF8, PIM1, POLA1, POLB, PPARA, PTAFR, PTPN1, PTPRS, RORC, SMAD3, SRC, TBXAS1, TEK, THRA, THRB, TNKS, TNKS2, TOP1, TOP2A, TYR, XDH |
7.62773 |
|
[BP] GO:0032502 |
developmental process
|
ACHE, ADORA1, ADRB1, AKR1B1, ALOX15, APEX1, AURKB, AXL, CA2, CA9, CACNA1C, CBR1, CDC25B, CDK6, CHRM2, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, DUSP3, EGFR, ERBB2, FABP4, FLT3, GLO1, HSD11B1, HSD17B2, INSR, KDR, KIT, MET, MMP2, MMP9, PHF8, PIM1, POLB, PPARA, PTPRS, RORC, SMAD3, SRC, TEK, THRA, THRB, TNKS2, TOP2A, TYR |
7.62212 |
|
[BP] GO:0046777 |
protein autophosphorylation
|
AURKB, CSNK2A1, EGFR, ERBB2, FLT3, IGF1R, INSR, KDR, KIT, PIM1, SRC, TEK |
7.57658 |
|
[BP] GO:0010646 |
regulation of cell communication
|
ACHE, ADORA1, ADRA2A, ADRA2C, ADRB1, AKR1B1, ALOX15, AURKB, AXL, CA2, CA7, CACNA1C, CSNK2A1, CYP19A1, CYP1B1, DUSP3, EGFR, ERBB2, F10, FLT3, GPR35, HSPA1A, IGF1R, INSR, KDR, KIT, MET, MMP12, MMP9, NR1H4, NUAK1, PTPN1, PTPRS, SMAD3, SRC, TEK, THRA, TNKS, TNKS2, XDH |
7.57658 |
|
[BP] GO:0019748 |
secondary metabolic process
|
AKR1B1, AKR1B10, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, TYR |
7.53699 |
|
[BP] GO:0048584 |
positive regulation of response to stimulus
|
ADORA1, ADRA2A, ADRA2C, ADRB1, AKR1B1, ALOX15, AXL, CSNK2A1, CYP1B1, EGFR, ERBB2, F10, FABP4, FLT3, GPR35, HSPA1A, INSR, KDR, KIT, MET, MMP12, MMP2, MMP9, NR1H4, PTAFR, PTPN1, SMAD3, SRC, TEK, TNKS, TNKS2, XDH |
7.52686 |
|
[BP] GO:1902533 |
positive regulation of intracellular signal transduction
|
ADORA1, ADRA2A, ADRA2C, ADRB1, AKR1B1, ALOX15, AXL, CYP1B1, EGFR, ERBB2, F10, FLT3, GPR35, HSPA1A, INSR, KDR, KIT, MET, PTPN1, SRC, TEK, XDH |
7.47618 |
|
[BP] GO:0023051 |
regulation of signaling
|
ACHE, ADORA1, ADRA2A, ADRA2C, ADRB1, AKR1B1, ALOX15, AURKB, AXL, CA2, CA7, CACNA1C, CSNK2A1, CYP19A1, CYP1B1, DUSP3, EGFR, ERBB2, F10, FLT3, GPR35, HSPA1A, IGF1R, INSR, KDR, KIT, MET, MMP12, MMP9, NR1H4, NUAK1, PTPN1, PTPRS, SMAD3, SRC, TEK, THRA, TNKS, TNKS2, XDH |
7.47618 |
|
[BP] GO:0019369 |
arachidonic acid metabolic process
|
ALOX15, CBR1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, TBXAS1 |
7.39252 |
|
[BP] GO:0051270 |
regulation of cellular component movement
|
ADORA1, ADORA3, ADRA2A, APEX1, CACNA1C, CDK6, CYP19A1, CYP1B1, EGFR, ERBB2, F10, IGF1R, INSR, KDR, KIT, MET, MMP9, PTAFR, SMAD3, SRC, TEK |
7.38484 |
|
[BP] GO:1902531 |
regulation of intracellular signal transduction
|
ADORA1, ADRA2A, ADRA2C, ADRB1, AKR1B1, ALOX15, AURKB, AXL, CSNK2A1, CYP1B1, DUSP3, EGFR, ERBB2, F10, FLT3, GPR35, HSPA1A, IGF1R, INSR, KDR, KIT, MET, MMP9, NR1H4, NUAK1, PTPN1, SRC, TEK, XDH |
7.35516 |
|
[BP] GO:0044281 |
small molecule metabolic process
|
AKR1B1, AKR1B10, ALOX15, ALOX5, CA1, CA12, CA2, CA4, CA7, CA9, CBR1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, DAO, FABP3, GLO1, HSPA1A, NR1H4, PIM1, PPARA, PTAFR, TBXAS1, TYR, XDH |
7.22861 |
|
[BP] GO:2000145 |
regulation of cell motility
|
ADORA1, ADORA3, ADRA2A, APEX1, CDK6, CYP19A1, CYP1B1, EGFR, ERBB2, F10, IGF1R, INSR, KDR, KIT, MET, MMP9, PTAFR, SMAD3, SRC, TEK |
7.21053 |
|
[BP] GO:0042127 |
regulation of cell proliferation
|
ADORA1, ADORA3, ADRA2A, AKR1B1, CDC25B, CDK6, CSNK2A1, CYP1B1, EGFR, ERBB2, FABP3, FLT3, HSPA1A, IGF1R, INSR, KDR, KIT, MMP12, MMP2, MMP9, NUAK1, PIM1, PTAFR, SMAD3, SRC, TEK, XDH |
7.01402 |
|
[BP] GO:1901700 |
response to oxygen-containing compound
|
AKR1B1, APEX1, AXL, CA9, CDK6, CSNK2A1, CYP1A1, CYP1A2, CYP1B1, EGFR, FABP3, HSD17B2, IGF1R, INSR, MMP2, MMP9, NR1H4, POLB, PPARA, PTAFR, RORC, SRC, TEK, TYR |
6.97907 |
|
[BP] GO:0033559 |
unsaturated fatty acid metabolic process
|
ALOX15, ALOX5, CBR1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, TBXAS1 |
6.91459 |
|
[BP] GO:0018108 |
peptidyl-tyrosine phosphorylation
|
AXL, EGFR, ERBB2, FLT3, IGF1R, INSR, KDR, KIT, MET, SRC, TEK |
6.84529 |
|
[BP] GO:0009719 |
response to endogenous stimulus
|
ADRA2A, AKR1B1, APEX1, CA2, CA9, CSNK2A1, CYP1A2, EGFR, ERBB2, FABP3, FLT3, IGF1R, INSR, KIT, MMP2, NR1H4, PPARA, PTAFR, SMAD3, SRC, TEK |
6.79033 |
|
[BP] GO:0018212 |
peptidyl-tyrosine modification
|
AXL, EGFR, ERBB2, FLT3, IGF1R, INSR, KDR, KIT, MET, SRC, TEK |
6.79033 |
|
[BP] GO:0006796 |
phosphate-containing compound metabolic process
|
ACHE, ALOX15, APEX1, AURKB, AXL, CDC25B, CDK6, CSNK2A1, DUSP3, EGFR, ERBB2, FLT3, HSPA1A, IGF1R, INSR, KDR, KIT, MET, NUAK1, PIM1, POLB, PTAFR, PTPN1, PTPRS, SRC, TEK, TNKS, TOP1, XDH |
6.74266 |
|
[BP] GO:0040012 |
regulation of locomotion
|
ADORA1, ADORA3, ADRA2A, APEX1, CDK6, CYP19A1, CYP1B1, EGFR, ERBB2, F10, IGF1R, INSR, KDR, KIT, MET, MMP9, PTAFR, SMAD3, SRC, TEK |
6.73054 |
|
[BP] GO:0006690 |
icosanoid metabolic process
|
ALOX15, ALOX5, CBR1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, TBXAS1 |
6.70593 |
|
[BP] GO:0055114 |
oxidation-reduction process
|
AKR1B1, AKR1B10, ALOX15, ALOX5, APEX1, CBR1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, DAO, HSD11B1, HSD17B1, HSD17B2, PHF8, TBXAS1, TYR, XDH |
6.70593 |
|
[BP] GO:0050896 |
response to stimulus
|
ABCB1, ACHE, ADORA1, ADORA3, ADRA2A, ADRB1, AKR1B1, ALOX15, APEX1, AURKB, AXL, CA2, CA9, CDK6, CHRM2, CSNK2A1, CYP1A1, CYP1A2, CYP1B1, EGFR, ERBB2, F10, FABP3, FABP4, FLT3, HSD17B2, HSPA1A, IGF1R, INSR, KDR, KIT, MMP12, MMP2, MMP9, NR1H4, NUAK1, POLA1, POLB, PPARA, PTAFR, PTPN1, RORC, SMAD3, SRC, TEK, THRA, TOP1, TOP2A, TYR |
6.66325 |
|
[BP] GO:0015701 |
bicarbonate transport
|
CA1, CA12, CA14, CA2, CA4, CA7, CA9 |
6.64439 |
|
[BP] GO:0048583 |
regulation of response to stimulus
|
ABCB1, ADORA1, ADRA2A, ADRA2C, ADRB1, AKR1B1, ALOX15, AURKB, AXL, CDK6, CSNK2A1, CYP19A1, CYP1B1, DUSP3, EGFR, ERBB2, F10, FABP4, FLT3, GPR35, HSPA1A, IGF1R, INSR, KDR, KIT, MET, MMP12, MMP2, MMP9, NR1H4, NUAK1, PPARA, PTAFR, PTPN1, PTPRS, SMAD3, SRC, TEK, THRA, TNKS, TNKS2, XDH |
6.6389 |
|
[BP] GO:0070887 |
cellular response to chemical stimulus
|
ADRA2A, AKR1B1, ALOX15, APEX1, AXL, CDK6, CYP1A1, CYP1A2, CYP1B1, EGFR, ERBB2, FABP4, FLT3, HSPA1A, IGF1R, INSR, KDR, KIT, MMP2, MMP9, NR1H4, PTAFR, RORC, SMAD3, SRC |
6.54666 |
|
[BP] GO:0010941 |
regulation of cell death
|
ADORA1, AKR1B1, APEX1, AURKB, AXL, CSNK2A1, CYP1B1, EGFR, FLT3, GLO1, HSPA1A, IGF1R, KDR, KIT, MET, MMP9, NR1H4, PIM1, PPARA, PTPN1, SMAD3, SRC, TEK, THRA, TOP2A, XDH |
6.39997 |
|
[BP] GO:0051716 |
cellular response to stimulus
|
ADRA2A, AKR1B1, ALOX15, APEX1, AURKB, AXL, CA2, CA9, CDK6, CYP1A1, CYP1A2, CYP1B1, EGFR, ERBB2, FABP4, FLT3, HSPA1A, IGF1R, INSR, KDR, KIT, MMP2, MMP9, NR1H4, NUAK1, POLA1, POLB, PTAFR, PTPN1, RORC, SMAD3, SRC, TOP2A |
6.39359 |
|
[BP] GO:0043067 |
regulation of programmed cell death
|
ADORA1, AKR1B1, APEX1, AURKB, AXL, CSNK2A1, CYP1B1, EGFR, FLT3, GLO1, HSPA1A, IGF1R, KDR, KIT, MET, MMP9, NR1H4, PIM1, PTPN1, SMAD3, SRC, TEK, THRA, TOP2A, XDH |
6.38071 |
|
[BP] GO:0006793 |
phosphorus metabolic process
|
ACHE, ALOX15, APEX1, AURKB, AXL, CDC25B, CDK6, CSNK2A1, DUSP3, EGFR, ERBB2, FLT3, HSPA1A, IGF1R, INSR, KDR, KIT, MET, NUAK1, PIM1, POLB, PTAFR, PTPN1, PTPRS, SRC, TEK, TNKS, TOP1, XDH |
6.38071 |
|
[BP] GO:0032501 |
multicellular organismal process
|
ADORA1, ADRA2A, ADRA2C, ADRB1, AKR1B1, AKR1B10, ALOX15, ALOX5, AXL, CACNA1C, CYP19A1, CYP1A2, CYP1B1, DUSP3, EGFR, F10, FABP4, HSD17B2, IGF1R, INSR, KIT, MET, MMP1, MMP12, MMP2, MMP9, PIM1, PPARA, PTAFR, RORC, SMAD3, SRC, TEK, THRA, THRB, TNKS2, TOP1, TYR |
6.36316 |
|
[BP] GO:0060548 |
negative regulation of cell death
|
ADORA1, AKR1B1, AURKB, AXL, CSNK2A1, EGFR, GLO1, HSPA1A, IGF1R, KDR, KIT, MET, MMP9, NR1H4, PIM1, PPARA, PTPN1, SMAD3, SRC, TEK |
6.34339 |
|
[BP] GO:0043069 |
negative regulation of programmed cell death
|
ADORA1, AKR1B1, AURKB, AXL, CSNK2A1, EGFR, GLO1, HSPA1A, IGF1R, KDR, KIT, MET, MMP9, NR1H4, PIM1, PTPN1, SMAD3, SRC, TEK |
6.1841 |
|
[BP] GO:0030334 |
regulation of cell migration
|
ADORA1, ADORA3, ADRA2A, APEX1, CYP19A1, CYP1B1, EGFR, F10, IGF1R, INSR, KDR, KIT, MET, MMP9, PTAFR, SMAD3, SRC, TEK |
6.1662 |
|
[BP] GO:0044238 |
primary metabolic process
|
ACHE, ADORA1, AKR1B1, AKR1B10, ALOX15, ALOX5, APEX1, AURKB, AXL, CBR1, CDC25B, CDK6, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, DAO, DUSP3, EGFR, ERBB2, F10, FABP3, FABP4, FLT3, GLO1, HSD11B1, HSD17B1, HSD17B2, HSPA1A, IGF1R, INSR, KDR, KIT, MET, MMP1, MMP12, MMP2, MMP9, NR1H4, NUAK1, PHF8, PIM1, POLA1, POLB, PPARA, PTPN1, PTPRS, RORC, SMAD3, SRC, TBXAS1, TEK, THRA, THRB, TNKS, TNKS2, TOP1, TOP2A, TYR, XDH |
6.06811 |
|
[BP] GO:0010562 |
positive regulation of phosphorus metabolic process
|
ADORA1, ADRA2A, ADRA2C, ADRB1, ALOX15, CDC25B, EGFR, ERBB2, FABP3, FLT3, INSR, KDR, KIT, MMP9, NR1H4, PTAFR, PTPN1, SMAD3, SRC, TEK, XDH |
6.06811 |
|
[BP] GO:0045937 |
positive regulation of phosphate metabolic process
|
ADORA1, ADRA2A, ADRA2C, ADRB1, ALOX15, CDC25B, EGFR, ERBB2, FABP3, FLT3, INSR, KDR, KIT, MMP9, NR1H4, PTAFR, PTPN1, SMAD3, SRC, TEK, XDH |
6.06811 |
|
[BP] GO:0071310 |
cellular response to organic substance
|
ADRA2A, AKR1B1, ALOX15, APEX1, AXL, CDK6, CYP1A1, CYP1B1, EGFR, ERBB2, FABP4, FLT3, IGF1R, INSR, KDR, KIT, MMP2, NR1H4, PTAFR, RORC, SMAD3, SRC |
6.06811 |
|
[BP] GO:0019220 |
regulation of phosphate metabolic process
|
ADORA1, ADRA2A, ADRA2C, ADRB1, ALOX15, CDC25B, DUSP3, EGFR, ERBB2, FABP3, FABP4, FLT3, IGF1R, INSR, KDR, KIT, MMP9, NR1H4, NUAK1, PPARA, PTAFR, PTPN1, SMAD3, SRC, TEK, XDH |
5.96205 |
|
[BP] GO:0009966 |
regulation of signal transduction
|
ADORA1, ADRA2A, ADRA2C, ADRB1, AKR1B1, ALOX15, AURKB, AXL, CSNK2A1, CYP1B1, DUSP3, EGFR, ERBB2, F10, FLT3, GPR35, HSPA1A, IGF1R, INSR, KDR, KIT, MET, MMP12, MMP9, NR1H4, NUAK1, PTPN1, PTPRS, SMAD3, SRC, TEK, THRA, TNKS, TNKS2, XDH |
5.94027 |
|
[BP] GO:0051173 |
positive regulation of nitrogen compound metabolic process
|
ADORA1, ADRA2A, ADRA2C, ADRB1, ALOX15, AURKB, CDC25B, CSNK2A1, EGFR, ERBB2, FLT3, HSPA1A, IGF1R, INSR, KDR, KIT, MET, MMP12, MMP9, NR1H4, PHF8, PPARA, PTAFR, PTPN1, RORC, SMAD3, SRC, TEK, THRA, THRB, TNKS, TNKS2, TOP2A, XDH |
5.91263 |
|
[BP] GO:0051174 |
regulation of phosphorus metabolic process
|
ADORA1, ADRA2A, ADRA2C, ADRB1, ALOX15, CDC25B, DUSP3, EGFR, ERBB2, FABP3, FABP4, FLT3, IGF1R, INSR, KDR, KIT, MMP9, NR1H4, NUAK1, PPARA, PTAFR, PTPN1, SMAD3, SRC, TEK, XDH |
5.90698 |
|
[BP] GO:0008202 |
steroid metabolic process
|
AKR1B1, AKR1B10, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A6, HSD11B1, HSD17B1, HSD17B2, NR1H4 |
5.78786 |
|
[BP] GO:0010035 |
response to inorganic substance
|
AKR1B1, ALOX15, APEX1, AXL, CA2, CYP1A1, CYP1A2, CYP1B1, EGFR, FABP4, KDR, KIT, MMP9, SRC |
5.78448 |
|
[BP] GO:0071704 |
organic substance metabolic process
|
ACHE, ADORA1, AKR1B1, AKR1B10, ALOX15, ALOX5, APEX1, AURKB, AXL, CBR1, CDC25B, CDK6, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, DAO, DUSP3, EGFR, ERBB2, F10, FABP3, FABP4, FLT3, GLO1, HSD11B1, HSD17B1, HSD17B2, HSPA1A, IGF1R, INSR, KDR, KIT, MET, MMP1, MMP12, MMP2, MMP9, NR1H4, NUAK1, PHF8, PIM1, POLA1, POLB, PPARA, PTAFR, PTPN1, PTPRS, RORC, SMAD3, SRC, TBXAS1, TEK, THRA, THRB, TNKS, TNKS2, TOP1, TOP2A, TYR, XDH |
5.76764 |
|
[BP] GO:0006468 |
protein phosphorylation
|
AURKB, AXL, CDC25B, CDK6, CSNK2A1, EGFR, ERBB2, FLT3, IGF1R, INSR, KDR, KIT, MET, NUAK1, PIM1, SRC, TEK, TNKS, TOP1 |
5.75685 |
|
[BP] GO:0048523 |
negative regulation of cellular process
|
ACHE, ADORA1, ADORA3, ADRA2A, ADRA2C, AKR1B1, APEX1, AURKB, AXL, CDK6, CSNK2A1, CYP19A1, CYP1B1, DUSP3, EGFR, ERBB2, FABP3, FABP4, GLO1, GPR35, HSPA1A, IGF1R, KDR, KIT, MET, MMP12, MMP9, NR1H4, PHF8, PIM1, PPARA, PTPN1, PTPRS, RORC, SMAD3, SRC, TEK, THRA, THRB, TNKS, TNKS2, TOP2A, XDH |
5.75685 |
|
[BP] GO:0006730 |
one-carbon metabolic process
|
CA1, CA12, CA2, CA4, CA7, CA9 |
5.70915 |
|
[BP] GO:0001676 |
long-chain fatty acid metabolic process
|
ALOX15, CBR1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, TBXAS1 |
5.66306 |
|
[BP] GO:0009725 |
response to hormone
|
ADRA2A, AKR1B1, APEX1, CA2, CA9, CSNK2A1, CYP1A2, EGFR, FABP3, FLT3, INSR, KIT, PPARA, PTAFR, SRC, TEK |
5.57934 |
|
[BP] GO:0044255 |
cellular lipid metabolic process
|
ACHE, AKR1B10, ALOX15, ALOX5, CBR1, CSNK2A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, EGFR, ERBB2, FABP3, FABP4, KIT, MET, PPARA, TBXAS1 |
5.57296 |
|
[BP] GO:0031325 |
positive regulation of cellular metabolic process
|
ADORA1, ADRA2A, ADRA2C, ADRB1, ALOX15, AURKB, CDC25B, EGFR, ERBB2, FABP3, FLT3, HSPA1A, IGF1R, INSR, KDR, KIT, MET, MMP12, MMP9, NR1H4, PHF8, PPARA, PTAFR, PTPN1, RORC, SMAD3, SRC, TEK, THRA, THRB, TNKS, TNKS2, TOP2A, XDH |
5.56531 |
|
[BP] GO:0048856 |
anatomical structure development
|
ACHE, ADORA1, AKR1B1, ALOX15, AXL, CA2, CACNA1C, CDK6, CHRM2, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, DUSP3, EGFR, ERBB2, FLT3, HSD11B1, HSD17B2, INSR, KDR, KIT, MMP9, PHF8, PIM1, POLB, PPARA, PTPRS, RORC, SMAD3, SRC, TEK, THRA, TYR |
5.54951 |
|
[BP] GO:0048519 |
negative regulation of biological process
|
ACHE, ADORA1, ADORA3, ADRA2A, ADRA2C, ADRB1, AKR1B1, ALOX15, APEX1, AURKB, AXL, CDK6, CSNK2A1, CYP19A1, CYP1B1, DUSP3, EGFR, ERBB2, FABP3, FABP4, GLO1, GPR35, HSPA1A, IGF1R, KDR, KIT, MET, MMP12, MMP9, NR1H4, PHF8, PIM1, PPARA, PTPN1, PTPRS, RORC, SMAD3, SRC, TEK, THRA, THRB, TNKS, TNKS2, TOP2A, XDH |
5.53682 |
|
[BP] GO:0051897 |
positive regulation of protein kinase B signaling
|
AXL, EGFR, ERBB2, F10, INSR, KIT, MET, SRC, TEK |
5.49288 |
|
[BP] GO:0018193 |
peptidyl-amino acid modification
|
AURKB, AXL, CSNK2A1, EGFR, ERBB2, F10, FLT3, IGF1R, INSR, KDR, KIT, MET, NR1H4, SRC, TEK, TNKS, TOP1, TOP2A |
5.44535 |
|
[BP] GO:0007169 |
transmembrane receptor protein tyrosine kinase signaling pathway
|
AXL, EGFR, ERBB2, FLT3, IGF1R, INSR, KDR, KIT, MET, MMP2, MMP9, PTPN1, SRC, TEK |
5.43784 |
|
[BP] GO:1901568 |
fatty acid derivative metabolic process
|
ALOX15, ALOX5, CBR1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, TBXAS1 |
5.43784 |
|
[BP] GO:0051896 |
regulation of protein kinase B signaling
|
AXL, EGFR, ERBB2, F10, INSR, KIT, MET, SRC, TEK, XDH |
5.42043 |
|
[BP] GO:0008284 |
positive regulation of cell proliferation
|
ADRA2A, AKR1B1, CDC25B, CDK6, CSNK2A1, EGFR, ERBB2, FLT3, IGF1R, INSR, KDR, KIT, MMP12, MMP2, MMP9, PIM1, PTAFR, TEK |
5.42043 |
|
[BP] GO:0010817 |
regulation of hormone levels
|
ACHE, ADORA1, ADRA2A, ADRA2C, AKR1B1, CACNA1C, CYP19A1, CYP1A1, CYP1B1, EGFR, HSD11B1, HSD17B1, HSD17B2, NR1H4 |
5.35276 |
|
[BP] GO:0042592 |
homeostatic process
|
ADORA1, ADRA2A, ADRB1, AKR1B1, APEX1, AXL, CA12, CA2, CA7, CACNA1C, EGFR, FABP3, FABP4, FLT3, GPR35, INSR, MET, NR1H4, POLA1, POLB, SMAD3, SRC |
5.34958 |
|
[BP] GO:0009893 |
positive regulation of metabolic process
|
ADORA1, ADRA2A, ADRA2C, ADRB1, ALOX15, AURKB, CDC25B, CSNK2A1, EGFR, ERBB2, FABP3, FLT3, HSPA1A, IGF1R, INSR, KDR, KIT, MET, MMP12, MMP9, NR1H4, PHF8, PPARA, PTAFR, PTPN1, RORC, SMAD3, SRC, TEK, THRA, THRB, TNKS, TNKS2, TOP2A, XDH |
5.34958 |
|
[BP] GO:0019373 |
epoxygenase P450 pathway
|
CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6 |
5.34958 |
|
[BP] GO:0043410 |
positive regulation of MAPK cascade
|
ADORA1, ADRA2A, ADRA2C, ALOX15, EGFR, ERBB2, FLT3, INSR, KDR, KIT, PTPN1, SRC, TEK, XDH |
5.34881 |
|
[BP] GO:1903727 |
positive regulation of phospholipid metabolic process
|
FABP3, FLT3, KIT, NR1H4, SRC, TEK |
5.32683 |
|
[BP] GO:1903522 |
None
|
ADORA1, ADORA3, ADRA2A, ADRA2C, ADRB1, CACNA1C, CHRM2, EGFR, PTAFR, THRA, THRB |
5.28298 |
|
[BP] GO:0044057 |
None
|
ADORA1, ADORA3, ADRA2A, ADRA2C, ADRB1, CACNA1C, CHRM2, EGFR, GPR35, KIT, PTAFR, SMAD3, THRA, THRB |
5.28298 |
|
[BP] GO:0042981 |
regulation of apoptotic process
|
ADORA1, AKR1B1, APEX1, AURKB, AXL, CSNK2A1, CYP1B1, EGFR, FLT3, GLO1, HSPA1A, IGF1R, KDR, MMP9, NR1H4, PIM1, PTPN1, SMAD3, SRC, TEK, THRA, TOP2A, XDH |
5.28298 |
|
[BP] GO:0019216 |
regulation of lipid metabolic process
|
ADORA1, ADRA2A, CYP1A1, FABP3, FLT3, KIT, NR1H4, PPARA, RORC, SRC, TEK, THRA |
5.20845 |
|
[BP] GO:0030335 |
positive regulation of cell migration
|
ADRA2A, EGFR, F10, IGF1R, INSR, KDR, KIT, MET, MMP9, PTAFR, SMAD3, SRC, TEK |
5.20845 |
|
[BP] GO:0043408 |
regulation of MAPK cascade
|
ADORA1, ADRA2A, ADRA2C, ALOX15, DUSP3, EGFR, ERBB2, FLT3, IGF1R, INSR, KDR, KIT, PTPN1, SRC, TEK, XDH |
5.17702 |
|
[BP] GO:0033993 |
response to lipid
|
AXL, CA2, CA9, CDK6, CSNK2A1, CYP1A1, CYP1A2, EGFR, FABP3, FLT3, HSD17B2, NR1H4, PTAFR, RORC, SRC, TYR |
5.15979 |
|
[BP] GO:0051239 |
regulation of multicellular organismal process
|
ADORA1, ADORA3, ADRA2A, ADRA2C, ADRB1, AXL, CA2, CACNA1C, CDK6, CHRM2, CYP1B1, EGFR, ERBB2, GPR35, HSPA1A, INSR, KDR, KIT, MET, MMP12, MMP9, NR1H4, PIM1, PTAFR, PTPRS, SMAD3, SRC, TEK, THRA, THRB, TNKS2, XDH |
5.14975 |
|
[BP] GO:0006631 |
fatty acid metabolic process
|
ALOX15, ALOX5, CBR1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, FABP3, PPARA, TBXAS1 |
5.14755 |
|
[BP] GO:2000147 |
positive regulation of cell motility
|
ADRA2A, EGFR, F10, IGF1R, INSR, KDR, KIT, MET, MMP9, PTAFR, SMAD3, SRC, TEK |
5.05845 |
|
[BP] GO:0010604 |
positive regulation of macromolecule metabolic process
|
ADORA1, ADRA2A, ADRA2C, ALOX15, AURKB, CDC25B, CSNK2A1, EGFR, ERBB2, FLT3, HSPA1A, IGF1R, INSR, KDR, KIT, MET, MMP12, MMP9, NR1H4, PHF8, PPARA, PTAFR, PTPN1, RORC, SMAD3, SRC, TEK, THRA, THRB, TNKS, TNKS2, TOP2A, XDH |
5.0492 |
|
[BP] GO:2001225 |
regulation of chloride transport
|
ABCB1, CA2, CA7, PTAFR |
4.99145 |
|
[BP] GO:0043066 |
negative regulation of apoptotic process
|
ADORA1, AKR1B1, AURKB, AXL, CSNK2A1, EGFR, GLO1, HSPA1A, IGF1R, KDR, MMP9, NR1H4, PIM1, PTPN1, SMAD3, SRC, TEK |
4.96026 |
|
[BP] GO:0051049 |
regulation of transport
|
ABCB1, ACHE, ADORA1, ADRA2A, ADRA2C, ALOX15, AXL, CA2, CA7, CACNA1C, CYP19A1, EGFR, ERBB2, GPR35, HSPA1A, INSR, MMP12, MMP9, NR1H4, PPARA, PTAFR, PTPN1, SMAD3, SRC, THRA |
4.95261 |
|
[BP] GO:0051272 |
positive regulation of cellular component movement
|
ADRA2A, EGFR, F10, IGF1R, INSR, KDR, KIT, MET, MMP9, PTAFR, SMAD3, SRC, TEK |
4.95245 |
|
[BP] GO:0032844 |
regulation of homeostatic process
|
ADORA1, ADRA2A, AURKB, CA2, CA7, CACNA1C, CDK6, EGFR, KDR, NR1H4, SRC, TNKS, TNKS2 |
4.91318 |
|
[BP] GO:0080134 |
regulation of response to stress
|
ABCB1, ADORA1, ADRA2A, CDK6, CYP19A1, DUSP3, EGFR, FABP4, HSPA1A, IGF1R, MET, MMP12, MMP2, NR1H4, NUAK1, PPARA, PTPN1, PTPRS, SMAD3, SRC, TEK, XDH |
4.9033 |
|
[BP] GO:0032787 |
None
|
ALOX15, ALOX5, CBR1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, FABP3, GLO1, NR1H4, PPARA, TBXAS1 |
4.87765 |
|
[BP] GO:0007167 |
enzyme linked receptor protein signaling pathway
|
AXL, EGFR, ERBB2, FLT3, IGF1R, INSR, KDR, KIT, MET, MMP2, MMP9, PTPN1, SMAD3, SRC, TEK |
4.79393 |
|
[BP] GO:0040017 |
positive regulation of locomotion
|
ADRA2A, EGFR, F10, IGF1R, INSR, KDR, KIT, MET, MMP9, PTAFR, SMAD3, SRC, TEK |
4.79393 |
|
[BP] GO:0009628 |
response to abiotic stimulus
|
ADORA1, ADRB1, AKR1B1, AURKB, CA2, CYP1A1, EGFR, HSPA1A, KIT, MMP2, POLB, PPARA, PTAFR, SMAD3, SRC, TEK, THRA, TYR |
4.73885 |
|
[BP] GO:0043405 |
regulation of MAP kinase activity
|
ADORA1, ADRA2A, DUSP3, EGFR, ERBB2, FLT3, IGF1R, INSR, KIT, PTPN1, SRC |
4.61778 |
|
[BP] GO:0016310 |
phosphorylation
|
AURKB, AXL, CDC25B, CDK6, CSNK2A1, EGFR, ERBB2, FLT3, IGF1R, INSR, KDR, KIT, MET, NUAK1, PIM1, SRC, TEK, TNKS, TOP1 |
4.55527 |
|
[BP] GO:0003018 |
None
|
ADORA1, ADRA2A, ADRA2C, ADRB1, EGFR, PTAFR, SRC, TEK |
4.39867 |
|
[BP] GO:0006940 |
None
|
ADORA1, ADRA2A, ADRA2C, CHRM2, KIT, PTAFR |
4.35543 |
|
[BP] GO:0006950 |
response to stress
|
ACHE, ADORA1, ADORA3, ADRB1, AKR1B1, ALOX15, APEX1, AXL, CA2, CA9, CYP1A1, CYP1A2, CYP1B1, EGFR, ERBB2, HSPA1A, KIT, MMP2, MMP9, NR1H4, NUAK1, POLA1, POLB, PPARA, PTAFR, PTPN1, SMAD3, SRC, TEK, THRA, TOP2A |
4.33399 |
|
[BP] GO:0042493 |
response to drug
|
ABCB1, AKR1B1, APEX1, AXL, CA9, CDK6, CYP1A1, CYP1B1, EGFR, FABP3, KDR, POLB, PTAFR, SRC, TOP1 |
4.33335 |
|
[BP] GO:0034614 |
cellular response to reactive oxygen species
|
AKR1B1, APEX1, AXL, CYP1B1, EGFR, MMP9, SRC |
4.31386 |
|
[BP] GO:0019752 |
carboxylic acid metabolic process
|
ALOX15, ALOX5, CBR1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, DAO, FABP3, GLO1, NR1H4, PIM1, PPARA, TBXAS1, TYR |
4.22779 |
|
[BP] GO:0008283 |
cell proliferation
|
ABCB1, ACHE, AURKB, CYP1A1, EGFR, ERBB2, FLT3, KIT, MET, PIM1, POLA1, SRC, TEK, TYR |
4.17928 |
|
[BP] GO:0048585 |
negative regulation of response to stimulus
|
ADORA1, ADRA2A, ALOX15, CDK6, CYP19A1, DUSP3, EGFR, ERBB2, HSPA1A, IGF1R, MET, MMP12, MMP9, NR1H4, PPARA, PTPN1, PTPRS, SMAD3, SRC, TEK, XDH |
4.17449 |
|
[BP] GO:1903725 |
regulation of phospholipid metabolic process
|
FABP3, FLT3, KIT, NR1H4, SRC, TEK |
4.11273 |
|
[BP] GO:0009987 |
cellular process
|
ABCB1, ACHE, ADORA1, ADORA3, ADRA2A, ADRA2C, ADRB1, AKR1B1, AKR1B10, ALOX15, ALOX5, APEX1, AURKB, AXL, CA1, CA12, CA2, CA4, CA7, CA9, CACNA1C, CBR1, CDC25B, CDK6, CHRM2, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, DAO, DUSP3, EGFR, ERBB2, F10, FABP3, FABP4, FLT3, GLO1, GPR35, HSD17B1, HSD17B2, HSPA1A, IGF1R, INSR, KDR, KIT, MET, MMP1, MMP12, MMP2, MMP9, NR1H4, NUAK1, PHF8, PIM1, POLA1, POLB, PPARA, PTAFR, PTPN1, PTPRS, RORC, SMAD3, SRC, TBXAS1, TEK, THRA, THRB, TNKS, TNKS2, TOP1, TOP2A, TUBB3, TYR, XDH |
4.05443 |
|
[BP] GO:0065009 |
regulation of molecular function
|
ABCB1, ADORA1, ADORA3, ADRA2A, ADRA2C, ADRB1, AURKB, CDC25B, CSNK2A1, CYP1B1, DUSP3, EGFR, ERBB2, FABP4, FLT3, GPR35, HSPA1A, IGF1R, INSR, KIT, MET, MMP9, NR1H4, NUAK1, PIM1, PPARA, PTAFR, PTPN1, SMAD3, SRC, TEK, TNKS, XDH |
4.01592 |
|
[BP] GO:0051338 |
regulation of transferase activity
|
ADORA1, ADRA2A, ADRA2C, AURKB, CDC25B, DUSP3, EGFR, ERBB2, FABP4, FLT3, IGF1R, INSR, KIT, PTPN1, SRC, TEK, TNKS |
3.99591 |
|
[BP] GO:0019222 |
regulation of metabolic process
|
ACHE, ADORA1, ADORA3, ADRA2A, ADRA2C, ADRB1, ALOX15, APEX1, AURKB, CA9, CDC25B, CDK6, CSNK2A1, CYP1A1, CYP1A2, CYP1B1, DUSP3, EGFR, ERBB2, FABP3, FABP4, FLT3, GLO1, HSPA1A, IGF1R, INSR, KDR, KIT, MET, MMP12, MMP9, NR1H4, NUAK1, PHF8, PIM1, POLA1, PPARA, PTAFR, PTPN1, RORC, SMAD3, SRC, TEK, THRA, THRB, TNKS, TNKS2, TOP1, TOP2A, XDH |
3.99115 |
|
[BP] GO:0071495 |
cellular response to endogenous stimulus
|
ADRA2A, AKR1B1, APEX1, EGFR, ERBB2, FLT3, IGF1R, INSR, KIT, MMP2, NR1H4, PTAFR, SMAD3, SRC |
3.98809 |
|
[BP] GO:0009611 |
response to wounding
|
ACHE, ADORA3, ALOX15, CYP1A1, EGFR, ERBB2, PPARA, SMAD3 |
3.98084 |
|
[BP] GO:0051347 |
positive regulation of transferase activity
|
ADORA1, ADRA2A, ADRA2C, AURKB, CDC25B, EGFR, ERBB2, FLT3, INSR, KIT, PTPN1, SRC, TEK, TNKS |
3.98084 |
|
[BP] GO:1901564 |
organonitrogen compound metabolic process
|
ACHE, AKR1B1, AURKB, AXL, CDC25B, CDK6, CSNK2A1, CYP1A1, CYP1A2, DAO, DUSP3, EGFR, ERBB2, F10, FLT3, GLO1, HSPA1A, IGF1R, INSR, KDR, KIT, MET, MMP1, MMP12, MMP2, MMP9, NR1H4, NUAK1, PHF8, PIM1, POLB, PPARA, PTPN1, PTPRS, SMAD3, SRC, TEK, TNKS, TNKS2, TOP1, TOP2A, TYR, XDH |
3.98084 |
|
[BP] GO:0045834 |
positive regulation of lipid metabolic process
|
FABP3, FLT3, KIT, NR1H4, PPARA, SRC, TEK |
3.98084 |
|
[BP] GO:0010648 |
negative regulation of cell communication
|
ACHE, ADORA1, ADRA2A, ADRA2C, DUSP3, EGFR, ERBB2, GPR35, HSPA1A, IGF1R, MET, MMP12, MMP9, NR1H4, PTPN1, PTPRS, SMAD3, SRC, XDH |
3.91221 |
|
[BP] GO:0023057 |
negative regulation of signaling
|
ACHE, ADORA1, ADRA2A, ADRA2C, DUSP3, EGFR, ERBB2, GPR35, HSPA1A, IGF1R, MET, MMP12, MMP9, NR1H4, PTPN1, PTPRS, SMAD3, SRC, XDH |
3.8946 |
|
[BP] GO:0042445 |
hormone metabolic process
|
ACHE, AKR1B1, CYP19A1, CYP1A1, CYP1B1, HSD11B1, HSD17B1, HSD17B2 |
3.88594 |
|
[BP] GO:0050790 |
regulation of catalytic activity
|
ADORA1, ADORA3, ADRA2A, ADRA2C, ADRB1, AURKB, CDC25B, CSNK2A1, DUSP3, EGFR, ERBB2, FABP4, FLT3, HSPA1A, IGF1R, INSR, KIT, MMP9, NUAK1, PTAFR, PTPN1, SMAD3, SRC, TEK, TNKS, XDH |
3.883 |
|
[BP] GO:0015711 |
organic anion transport
|
ABCB1, CA1, CA12, CA14, CA2, CA4, CA7, CA9, FABP3, NR1H4, PPARA |
3.81843 |
|
[BP] GO:0034599 |
cellular response to oxidative stress
|
AKR1B1, APEX1, AXL, CYP1B1, EGFR, HSPA1A, MMP9, SRC |
3.74636 |
|
[BP] GO:0001934 |
positive regulation of protein phosphorylation
|
ADORA1, ADRA2A, ADRA2C, ALOX15, CDC25B, EGFR, ERBB2, FLT3, INSR, KDR, KIT, MMP9, PTPN1, SRC, TEK, XDH |
3.74392 |
|
[BP] GO:0038083 |
peptidyl-tyrosine autophosphorylation
|
EGFR, IGF1R, INSR, KDR, SRC |
3.74035 |
|
[BP] GO:0043406 |
positive regulation of MAP kinase activity
|
ADORA1, ADRA2A, EGFR, ERBB2, FLT3, INSR, KIT, PTPN1, SRC |
3.74035 |
|
[BP] GO:0043436 |
oxoacid metabolic process
|
ALOX15, ALOX5, CBR1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, DAO, FABP3, GLO1, NR1H4, PIM1, PPARA, TBXAS1, TYR |
3.73954 |
|
[BP] GO:0014070 |
response to organic cyclic compound
|
APEX1, CA2, CA9, CSNK2A1, CYP1A1, CYP1A2, CYP1B1, EGFR, FLT3, PTAFR, RORC, SRC, TEK, TYR |
3.72913 |
|
[BP] GO:0044093 |
positive regulation of molecular function
|
ABCB1, ADORA1, ADRA2A, ADRA2C, ADRB1, AURKB, CDC25B, EGFR, ERBB2, FLT3, HSPA1A, INSR, KIT, MET, MMP9, PTAFR, PTPN1, SMAD3, SRC, TEK, TNKS, XDH |
3.72913 |
|
[BP] GO:0060255 |
regulation of macromolecule metabolic process
|
ACHE, ADORA1, ADORA3, ADRA2A, ADRA2C, ALOX15, APEX1, AURKB, CA9, CDC25B, CDK6, CSNK2A1, CYP1A2, CYP1B1, DUSP3, EGFR, ERBB2, FABP4, FLT3, GLO1, HSPA1A, IGF1R, INSR, KDR, KIT, MET, MMP12, MMP9, NR1H4, NUAK1, PHF8, PIM1, POLA1, PPARA, PTAFR, PTPN1, RORC, SMAD3, SRC, TEK, THRA, THRB, TNKS, TNKS2, TOP1, TOP2A, XDH |
3.71711 |
|
[BP] GO:0007165 |
signal transduction
|
ADORA1, ADORA3, ADRA2A, ADRA2C, ADRB1, AKR1B1, AXL, CA1, CA2, CACNA1C, CDK6, CHRM2, CSNK2A1, CYP1B1, EGFR, ERBB2, FLT3, GPR35, IGF1R, INSR, KDR, KIT, MET, MMP2, MMP9, NR1H4, NUAK1, PIM1, POLB, PPARA, PTAFR, PTPN1, RORC, SMAD3, SRC, TEK, THRA, THRB, TNKS, TNKS2 |
3.71711 |
|
[BP] GO:0006082 |
organic acid metabolic process
|
ALOX15, ALOX5, CBR1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, DAO, FABP3, GLO1, NR1H4, PIM1, PPARA, TBXAS1, TYR |
3.66371 |
|
[BP] GO:0043549 |
regulation of kinase activity
|
ADORA1, ADRA2A, ADRA2C, CDC25B, DUSP3, EGFR, ERBB2, FABP4, FLT3, IGF1R, INSR, KIT, PTPN1, SRC, TEK |
3.66371 |
|
[BP] GO:0003013 |
None
|
ADORA1, ADRA2A, ADRA2C, ADRB1, EGFR, PTAFR, SRC, TEK |
3.60623 |
|
[BP] GO:0042325 |
regulation of phosphorylation
|
ADORA1, ADRA2A, ADRA2C, ALOX15, CDC25B, DUSP3, EGFR, ERBB2, FABP4, FLT3, IGF1R, INSR, KDR, KIT, MMP9, PPARA, PTPN1, SRC, TEK, XDH |
3.56806 |
|
[BP] GO:0009698 |
phenylpropanoid metabolic process
|
CYP1A1, CYP2A13, CYP2A6 |
3.56806 |
|
[BP] GO:0009804 |
coumarin metabolic process
|
CYP1A1, CYP2A13, CYP2A6 |
3.56806 |
|
[BP] GO:1901701 |
cellular response to oxygen-containing compound
|
AKR1B1, APEX1, AXL, CDK6, CYP1B1, EGFR, IGF1R, INSR, MMP2, MMP9, NR1H4, PTAFR, RORC, SRC |
3.56806 |
|
[BP] GO:0035690 |
cellular response to drug
|
AKR1B1, APEX1, AXL, CDK6, CYP1B1, EGFR, KDR, PTAFR, SRC |
3.55218 |
|
[BP] GO:0033674 |
positive regulation of kinase activity
|
ADORA1, ADRA2A, ADRA2C, CDC25B, EGFR, ERBB2, FLT3, INSR, KIT, PTPN1, SRC, TEK |
3.55105 |
|
[BP] GO:0042327 |
positive regulation of phosphorylation
|
ADORA1, ADRA2A, ADRA2C, ALOX15, CDC25B, EGFR, ERBB2, FLT3, INSR, KDR, KIT, MMP9, PTPN1, SRC, TEK, XDH |
3.55105 |
|
[BP] GO:0048511 |
rhythmic process
|
AXL, CSNK2A1, EGFR, KIT, PPARA, RORC, SRC, TOP1, TOP2A |
3.53485 |
|
[BP] GO:0010243 |
response to organonitrogen compound
|
AKR1B1, APEX1, EGFR, FABP3, FLT3, IGF1R, INSR, MMP2, NR1H4, PPARA, PTAFR, SRC, TEK, TYR |
3.53485 |
|
[BP] GO:0001932 |
regulation of protein phosphorylation
|
ADORA1, ADRA2A, ADRA2C, ALOX15, CDC25B, DUSP3, EGFR, ERBB2, FABP4, FLT3, IGF1R, INSR, KDR, KIT, MMP9, PTPN1, SRC, TEK, XDH |
3.53397 |
|
[BP] GO:0008210 |
estrogen metabolic process
|
CYP19A1, CYP1B1, HSD17B1, HSD17B2 |
3.53047 |
|
[BP] GO:0009891 |
positive regulation of biosynthetic process
|
ADRB1, AURKB, EGFR, ERBB2, FABP3, IGF1R, INSR, KDR, MET, MMP12, NR1H4, PHF8, PPARA, PTAFR, RORC, SMAD3, SRC, THRA, THRB, TNKS, TNKS2, TOP2A |
3.52489 |
|
[BP] GO:0007346 |
regulation of mitotic cell cycle
|
APEX1, AURKB, CDC25B, CDK6, CYP1A1, DUSP3, EGFR, HSPA1A, INSR, PIM1, SMAD3, TNKS, TOP2A |
3.50574 |
|
[BP] GO:0035556 |
intracellular signal transduction
|
ADRA2A, ADRA2C, ADRB1, AKR1B1, AXL, CACNA1C, CYP1B1, EGFR, ERBB2, IGF1R, INSR, KDR, KIT, MET, NUAK1, POLB, PTAFR, PTPN1, SRC, TEK |
3.50574 |
|
[BP] GO:0080090 |
regulation of primary metabolic process
|
ADORA1, ADORA3, ADRA2A, ADRA2C, ADRB1, ALOX15, APEX1, AURKB, CA9, CDC25B, CSNK2A1, CYP1A1, CYP1B1, DUSP3, EGFR, ERBB2, FABP3, FABP4, FLT3, GLO1, HSPA1A, IGF1R, INSR, KDR, KIT, MET, MMP12, MMP9, NR1H4, NUAK1, PHF8, PIM1, POLA1, PPARA, PTAFR, PTPN1, RORC, SMAD3, SRC, TEK, THRA, THRB, TNKS, TNKS2, TOP2A, XDH |
3.47228 |
|
[BP] GO:1901184 |
None
|
ADORA1, ADRA2A, ADRA2C, EGFR, ERBB2, MMP9 |
3.4434 |
|
[BP] GO:0065007 |
biological regulation
|
ABCB1, ACHE, ADORA1, ADORA3, ADRA2A, ADRA2C, ADRB1, AKR1B1, ALOX15, APEX1, AURKB, AXL, CA1, CA12, CA2, CA7, CA9, CACNA1C, CDC25B, CDK6, CHRM2, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, DUSP3, EGFR, ERBB2, F10, FABP3, FABP4, FLT3, GLO1, GPR35, HSD11B1, HSD17B1, HSD17B2, HSPA1A, IGF1R, INSR, KDR, KIT, MET, MMP1, MMP12, MMP2, MMP9, NR1H4, NUAK1, PHF8, PIM1, POLA1, POLB, PPARA, PTAFR, PTPN1, PTPRS, RORC, SMAD3, SRC, TEK, THRA, THRB, TNKS, TNKS2, TOP1, TOP2A, XDH |
3.38956 |
|
[BP] GO:0031347 |
regulation of defense response
|
ADORA1, CYP19A1, EGFR, FABP4, HSPA1A, MMP12, MMP2, NR1H4, PPARA, PTPN1, PTPRS, SMAD3, SRC, TEK |
3.38956 |
|
[BP] GO:0045859 |
regulation of protein kinase activity
|
ADORA1, ADRA2A, ADRA2C, CDC25B, DUSP3, EGFR, ERBB2, FABP4, FLT3, IGF1R, INSR, KIT, PTPN1, SRC |
3.37893 |
|
[BP] GO:0043085 |
positive regulation of catalytic activity
|
ADORA1, ADRA2A, ADRA2C, ADRB1, AURKB, CDC25B, EGFR, ERBB2, FLT3, HSPA1A, INSR, KIT, PTAFR, PTPN1, SMAD3, SRC, TEK, TNKS, XDH |
3.37651 |
|
[BP] GO:0051701 |
interaction with host
|
AXL, EGFR, HSPA1A, INSR, MET, SMAD3, SRC |
3.37651 |
|
[BP] GO:0007166 |
cell surface receptor signaling pathway
|
ADORA1, ADORA3, AXL, CA1, CSNK2A1, EGFR, ERBB2, FLT3, GPR35, IGF1R, INSR, KDR, KIT, MET, MMP2, MMP9, NR1H4, PTAFR, PTPN1, SMAD3, SRC, TEK, TNKS, TNKS2 |
3.36689 |
|
[BP] GO:0090257 |
None
|
ADORA1, ADRA2A, ADRA2C, CACNA1C, CHRM2, KIT, PTAFR, SMAD3 |
3.33078 |
|
[BP] GO:0006937 |
None
|
ADORA1, ADRA2A, ADRA2C, CACNA1C, CHRM2, KIT, PTAFR |
3.33058 |
|
[BP] GO:0044092 |
negative regulation of molecular function
|
ADORA3, ADRA2A, AURKB, CSNK2A1, CYP1B1, DUSP3, FABP4, GPR35, IGF1R, MET, MMP9, NR1H4, PIM1, PPARA, PTPN1, SRC, TNKS |
3.32682 |
|
[BP] GO:0051171 |
regulation of nitrogen compound metabolic process
|
ADORA1, ADORA3, ADRA2A, ADRA2C, ADRB1, ALOX15, APEX1, AURKB, CA9, CDC25B, CSNK2A1, CYP1B1, DUSP3, EGFR, ERBB2, FABP3, FABP4, FLT3, GLO1, HSPA1A, IGF1R, INSR, KDR, KIT, MET, MMP12, MMP9, NR1H4, NUAK1, PHF8, PIM1, POLA1, PPARA, PTAFR, PTPN1, RORC, SMAD3, SRC, TEK, THRA, THRB, TNKS, TNKS2, TOP2A, XDH |
3.32682 |
|
[BP] GO:0045935 |
positive regulation of nucleobase-containing compound metabolic process
|
ADRB1, AURKB, EGFR, ERBB2, HSPA1A, IGF1R, INSR, MET, MMP12, NR1H4, PHF8, PPARA, PTPN1, RORC, SMAD3, SRC, THRA, THRB, TNKS, TNKS2, TOP2A |
3.32682 |
|
[BP] GO:0050730 |
None
|
ADORA1, ADRA2A, ADRA2C, EGFR, FLT3, KIT, PTPN1, SRC |
3.30082 |
|
[BP] GO:0042446 |
hormone biosynthetic process
|
AKR1B1, CYP19A1, HSD11B1, HSD17B1, HSD17B2 |
3.28581 |
|
[BP] GO:0090087 |
None
|
ACHE, ADORA1, ADRA2A, ADRA2C, CA2, CACNA1C, EGFR, ERBB2, MMP12, NR1H4, PTPN1, SMAD3, SRC, THRA |
3.26182 |
|
[BP] GO:0034754 |
cellular hormone metabolic process
|
AKR1B1, CYP19A1, CYP1A1, CYP1B1, HSD17B1, HSD17B2 |
3.25986 |
|
[BP] GO:0031323 |
regulation of cellular metabolic process
|
ACHE, ADORA1, ADORA3, ADRA2A, ADRA2C, ADRB1, ALOX15, APEX1, AURKB, CA9, CDC25B, CSNK2A1, CYP1B1, DUSP3, EGFR, ERBB2, FABP3, FABP4, FLT3, GLO1, HSPA1A, IGF1R, INSR, KDR, KIT, MET, MMP12, MMP9, NR1H4, NUAK1, PHF8, PIM1, POLA1, PPARA, PTAFR, PTPN1, RORC, SMAD3, SRC, TEK, THRA, THRB, TNKS, TNKS2, TOP2A, XDH |
3.24957 |
|
[BP] GO:1901698 |
response to nitrogen compound
|
AKR1B1, APEX1, EGFR, FABP3, FLT3, IGF1R, INSR, MMP2, NR1H4, PPARA, PTAFR, SRC, TEK, TYR |
3.21299 |
|
[BP] GO:0043552 |
positive regulation of phosphatidylinositol 3-kinase activity
|
FLT3, KIT, SRC, TEK |
3.18384 |
|
[BP] GO:0071900 |
regulation of protein serine/threonine kinase activity
|
ADORA1, ADRA2A, DUSP3, EGFR, ERBB2, FLT3, IGF1R, INSR, KIT, PTPN1, SRC |
3.18351 |
|
[BP] GO:0031348 |
negative regulation of defense response
|
ADORA1, CYP19A1, MMP12, NR1H4, PPARA, SMAD3, TEK |
3.18351 |
|
[BP] GO:0051247 |
positive regulation of protein metabolic process
|
ADORA1, ADRA2A, ADRA2C, ALOX15, CDC25B, CSNK2A1, EGFR, ERBB2, FLT3, HSPA1A, INSR, KDR, KIT, MMP9, PTAFR, PTPN1, SMAD3, SRC, TEK, XDH |
3.17386 |
|
[BP] GO:0001101 |
response to acid chemical
|
AKR1B1, EGFR, FABP3, HSD17B2, KDR, MMP2, NR1H4, PTAFR, SRC |
3.16626 |
|
[BP] GO:0031399 |
regulation of protein modification process
|
ADORA1, ADRA2A, ADRA2C, ALOX15, CDC25B, DUSP3, EGFR, ERBB2, FABP4, FLT3, HSPA1A, IGF1R, INSR, KDR, KIT, MMP9, NUAK1, PTPN1, SRC, TEK, XDH |
3.16169 |
|
[BP] GO:0050731 |
positive regulation of peptidyl-tyrosine phosphorylation
|
ADORA1, ADRA2A, ADRA2C, FLT3, KIT, PTPN1, SRC |
3.15785 |
|
[BP] GO:0000302 |
response to reactive oxygen species
|
AKR1B1, APEX1, AXL, CYP1B1, EGFR, MMP9, SRC |
3.14488 |
|
[BP] GO:0001503 |
ossification
|
ALOX15, EGFR, MMP2, MMP9, TEK, THRA |
3.14488 |
|
[BP] GO:1901615 |
organic hydroxy compound metabolic process
|
AKR1B1, AKR1B10, ALOX15, CYP19A1, CYP1A1, CYP1B1, DAO, NR1H4, PTAFR, TYR |
3.13914 |
|
[BP] GO:0031328 |
positive regulation of cellular biosynthetic process
|
ADRB1, AURKB, EGFR, ERBB2, FABP3, IGF1R, INSR, MET, MMP12, NR1H4, PHF8, PPARA, PTAFR, RORC, SMAD3, SRC, THRA, THRB, TNKS, TNKS2, TOP2A |
3.13704 |
|
[BP] GO:0097267 |
omega-hydroxylase P450 pathway
|
CYP1A1, CYP1A2, CYP1B1 |
3.13704 |
|
[BP] GO:0030522 |
intracellular receptor signaling pathway
|
NR1H4, PIM1, PPARA, RORC, SRC, THRA, THRB |
3.13612 |
|
[BP] GO:0050728 |
negative regulation of inflammatory response
|
ADORA1, CYP19A1, NR1H4, PPARA, SMAD3, TEK |
3.13222 |
|
[BP] GO:0010638 |
positive regulation of organelle organization
|
ALOX15, AURKB, HSPA1A, INSR, KDR, MET, MMP9, SMAD3, SRC, TEK, TNKS, TNKS2 |
3.1321 |
|
[BP] GO:0045860 |
positive regulation of protein kinase activity
|
ADORA1, ADRA2A, ADRA2C, CDC25B, EGFR, ERBB2, FLT3, INSR, KIT, PTPN1, SRC |
3.12197 |
|
[BP] GO:0051050 |
positive regulation of transport
|
ABCB1, ACHE, ADORA1, ADRA2A, AXL, CA2, CYP19A1, EGFR, ERBB2, INSR, MMP12, NR1H4, PTAFR, SMAD3, SRC |
3.11811 |
|
[BP] GO:0090218 |
positive regulation of lipid kinase activity
|
FLT3, KIT, SRC, TEK |
3.04845 |
|
[BP] GO:0006464 |
cellular protein modification process
|
AURKB, AXL, CDC25B, CDK6, CSNK2A1, DUSP3, EGFR, ERBB2, F10, FLT3, IGF1R, INSR, KDR, KIT, MET, NR1H4, NUAK1, PHF8, PIM1, POLB, PTPN1, PTPRS, SMAD3, SRC, TEK, TNKS, TNKS2, TOP1, TOP2A |
3.04461 |
|
[BP] GO:0036211 |
protein modification process
|
AURKB, AXL, CDC25B, CDK6, CSNK2A1, DUSP3, EGFR, ERBB2, F10, FLT3, IGF1R, INSR, KDR, KIT, MET, NR1H4, NUAK1, PHF8, PIM1, POLB, PTPN1, PTPRS, SMAD3, SRC, TEK, TNKS, TNKS2, TOP1, TOP2A |
3.04461 |
|
[BP] GO:0010557 |
positive regulation of macromolecule biosynthetic process
|
AURKB, EGFR, ERBB2, IGF1R, INSR, KDR, MET, MMP12, NR1H4, PHF8, PPARA, PTAFR, RORC, SMAD3, SRC, THRA, THRB, TNKS, TNKS2, TOP2A |
3.04444 |
|
[BP] GO:0017144 |
drug metabolic process
|
ACHE, AKR1B1, AKR1B10, CBR1, CYP1A1, CYP1A2, CYP1B1, CYP2A6, DAO, EGFR, HSPA1A |
3.02647 |
|
[BP] GO:0044267 |
cellular protein metabolic process
|
AURKB, AXL, CDC25B, CDK6, CSNK2A1, DUSP3, EGFR, ERBB2, F10, FLT3, IGF1R, INSR, KDR, KIT, MET, MMP1, MMP2, NR1H4, NUAK1, PHF8, PIM1, POLB, PTPN1, PTPRS, SMAD3, SRC, TEK, TNKS, TNKS2, TOP1, TOP2A |
3.02607 |
|
[BP] GO:0032148 |
None
|
ADRA2A, ADRA2C, INSR, SRC |
3.01096 |
|
[BP] GO:0051704 |
multi-organism process
|
ADRA2C, AXL, CDK6, CHRM2, CYP1A1, EGFR, HSPA1A, INSR, KDR, MET, MMP1, MMP12, NR1H4, POLA1, PTAFR, SMAD3, SRC, TOP1 |
3.01096 |
|
[BP] GO:0032270 |
positive regulation of cellular protein metabolic process
|
ADORA1, ADRA2A, ADRA2C, ALOX15, CDC25B, EGFR, ERBB2, FLT3, HSPA1A, INSR, KDR, KIT, MMP9, PTAFR, PTPN1, SMAD3, SRC, TEK, XDH |
2.99525 |
|
[BP] GO:0051240 |
positive regulation of multicellular organismal process
|
ADRA2A, ADRA2C, ADRB1, AXL, CA2, CYP1B1, EGFR, HSPA1A, KDR, KIT, MET, MMP12, MMP9, NR1H4, PIM1, PTAFR, SMAD3, SRC, TEK |
2.98488 |
|
[BP] GO:0097746 |
None
|
ADORA1, ADRA2A, ADRA2C, ADRB1, EGFR, PTAFR |
2.97882 |
|
[BP] GO:0035296 |
None
|
ADORA1, ADRA2A, ADRA2C, ADRB1, EGFR, PTAFR |
2.97882 |
|
[BP] GO:0071902 |
positive regulation of protein serine/threonine kinase activity
|
ADORA1, ADRA2A, EGFR, ERBB2, FLT3, INSR, KIT, PTPN1, SRC |
2.91961 |
|
[BP] GO:0045741 |
None
|
ADORA1, ADRA2A, ADRA2C |
2.91828 |
|
[BP] GO:0006820 |
anion transport
|
ABCB1, CA1, CA12, CA14, CA2, CA4, CA7, CA9, FABP3, NR1H4, PPARA |
2.91828 |
|
[BP] GO:0019538 |
protein metabolic process
|
ACHE, AURKB, AXL, CDC25B, CDK6, CSNK2A1, DUSP3, EGFR, ERBB2, F10, FLT3, IGF1R, INSR, KDR, KIT, MET, MMP1, MMP12, MMP2, MMP9, NR1H4, NUAK1, PHF8, PIM1, POLB, PPARA, PTPN1, PTPRS, SMAD3, SRC, TEK, TNKS, TNKS2, TOP1, TOP2A |
2.91804 |
|
[BP] GO:0051128 |
regulation of cellular component organization
|
ALOX15, AURKB, AXL, CSNK2A1, EGFR, ERBB2, HSPA1A, IGF1R, INSR, KDR, KIT, MET, MMP1, MMP9, PHF8, PTPN1, PTPRS, SMAD3, SRC, TEK, THRA, TNKS, TNKS2, TOP2A |
2.91784 |
|
[BP] GO:0048661 |
positive regulation of smooth muscle cell proliferation
|
AKR1B1, EGFR, MMP2, MMP9, PTAFR |
2.89424 |
|
[BP] GO:0045742 |
None
|
ADORA1, ADRA2A, ADRA2C, MMP9 |
2.88292 |
|
[BP] GO:0043401 |
steroid hormone mediated signaling pathway
|
NR1H4, PPARA, RORC, SRC, THRA, THRB |
2.8796 |
|
[BP] GO:0042060 |
None
|
ALOX15, EGFR, ERBB2, PPARA, SMAD3 |
2.87874 |
|
[BP] GO:0008050 |
None
|
THRA, THRB |
2.87874 |
|
[BP] GO:0006286 |
base-excision repair, base-free sugar-phosphate removal
|
APEX1, POLB |
2.87874 |
|
[BP] GO:0070372 |
regulation of ERK1 and ERK2 cascade
|
ALOX15, DUSP3, EGFR, ERBB2, KDR, PTPN1, SRC, TEK |
2.86016 |
|
[BP] GO:0050880 |
None
|
ADORA1, ADRA2A, ADRA2C, ADRB1, EGFR, PTAFR |
2.85443 |
|
[BP] GO:0035150 |
None
|
ADORA1, ADRA2A, ADRA2C, ADRB1, EGFR, PTAFR |
2.83735 |
|
[BP] GO:0006703 |
estrogen biosynthetic process
|
CYP19A1, HSD17B1, HSD17B2 |
2.83533 |
|
[BP] GO:0030155 |
regulation of cell adhesion
|
ALOX15, CDK6, CYP1B1, DUSP3, ERBB2, KDR, NUAK1, PPARA, PTAFR, SMAD3, SRC, TEK |
2.83391 |
|
[BP] GO:1901186 |
None
|
ADORA1, ADRA2A, ADRA2C, MMP9 |
2.81383 |
|
[BP] GO:0051130 |
positive regulation of cellular component organization
|
ALOX15, AURKB, AXL, HSPA1A, IGF1R, INSR, KDR, KIT, MET, MMP1, MMP9, SMAD3, SRC, TEK, TNKS, TNKS2 |
2.7908 |
|
[BP] GO:0043412 |
macromolecule modification
|
APEX1, AURKB, AXL, CDC25B, CDK6, CSNK2A1, DUSP3, EGFR, ERBB2, F10, FLT3, IGF1R, INSR, KDR, KIT, MET, NR1H4, NUAK1, PHF8, PIM1, POLB, PTPN1, PTPRS, SMAD3, SRC, TEK, TNKS, TNKS2, TOP1, TOP2A |
2.77974 |
|
[BP] GO:0044070 |
regulation of anion transport
|
ABCB1, ADORA1, CA2, CA7, PTAFR |
2.76295 |
|
[BP] GO:0045776 |
None
|
ADORA1, ADRB1, PPARA, PTAFR |
2.69168 |
|
[BP] GO:0070482 |
response to oxygen levels
|
ADORA1, CYP1A1, MMP2, POLB, PPARA, SMAD3, SRC, TEK |
2.68964 |
|
[BP] GO:0042058 |
None
|
ADORA1, ADRA2A, ADRA2C, EGFR, MMP9 |
2.67012 |
|
[BP] GO:0051054 |
positive regulation of DNA metabolic process
|
AURKB, EGFR, IGF1R, INSR, SRC, TNKS, TNKS2 |
2.67012 |
|
[BP] GO:0061098 |
None
|
ADORA1, ADRA2A, ADRA2C, PTPN1 |
2.65953 |
|
[BP] GO:0043551 |
regulation of phosphatidylinositol 3-kinase activity
|
FLT3, KIT, SRC, TEK |
2.65953 |
|
[BP] GO:0048878 |
chemical homeostasis
|
ADRA2A, AKR1B1, CA12, CA2, CA7, CACNA1C, EGFR, FABP3, FABP4, GPR35, INSR, MET, NR1H4, SMAD3 |
2.64505 |
|
[BP] GO:0031401 |
positive regulation of protein modification process
|
ADORA1, ADRA2A, ADRA2C, ALOX15, CDC25B, EGFR, ERBB2, FLT3, INSR, KDR, KIT, MMP9, PTPN1, SRC, TEK, XDH |
2.64422 |
|
[BP] GO:0050789 |
regulation of biological process
|
ABCB1, ACHE, ADORA1, ADORA3, ADRA2A, ADRA2C, ADRB1, AKR1B1, ALOX15, APEX1, AURKB, AXL, CA1, CA2, CA7, CA9, CACNA1C, CDC25B, CDK6, CHRM2, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, DUSP3, EGFR, ERBB2, F10, FABP3, FABP4, FLT3, GLO1, GPR35, HSPA1A, IGF1R, INSR, KDR, KIT, MET, MMP1, MMP12, MMP2, MMP9, NR1H4, NUAK1, PHF8, PIM1, POLA1, POLB, PPARA, PTAFR, PTPN1, PTPRS, RORC, SMAD3, SRC, TEK, THRA, THRB, TNKS, TNKS2, TOP1, TOP2A, XDH |
2.64092 |
|
[BP] GO:0022414 |
reproductive process
|
ADRA2C, AKR1B1, AXL, CDC25B, CYP19A1, CYP1A1, EGFR, HSD17B2, INSR, KIT, MMP2, MMP9, PTAFR, SRC, THRA, THRB, TOP2A |
2.61304 |
|
[BP] GO:0071248 |
cellular response to metal ion
|
ALOX15, CYP1A1, CYP1A2, EGFR, FABP4, MMP9 |
2.6049 |
|
[BP] GO:0001954 |
positive regulation of cell-matrix adhesion
|
CDK6, KDR, SMAD3, TEK |
2.59059 |
|
[BP] GO:0071417 |
cellular response to organonitrogen compound
|
AKR1B1, APEX1, EGFR, IGF1R, INSR, MMP2, NR1H4, PTAFR, SRC |
2.57992 |
|
[BP] GO:0032846 |
positive regulation of homeostatic process
|
AURKB, CA2, CA7, EGFR, NR1H4, TNKS, TNKS2 |
2.52496 |
|
[BP] GO:0002682 |
regulation of immune system process
|
ADORA1, ALOX15, AXL, CA2, CDK6, CYP19A1, DUSP3, ERBB2, HSPA1A, KIT, MMP12, MMP2, NR1H4, PTAFR, PTPN1, PTPRS, SMAD3, SRC |
2.51758 |
|
[BP] GO:0009056 |
catabolic process
|
ACHE, ADORA1, AKR1B10, AURKB, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A6, DAO, FABP3, FABP4, HSPA1A, MMP1, MMP12, MMP2, MMP9, SRC, XDH |
2.51244 |
|
[BP] GO:0046486 |
glycerolipid metabolic process
|
ACHE, ALOX15, CSNK2A1, EGFR, ERBB2, FABP3, FABP4, KIT, MET |
2.51198 |
|
[BP] GO:1904355 |
positive regulation of telomere capping
|
AURKB, TNKS, TNKS2 |
2.50535 |
|
[BP] GO:0002683 |
negative regulation of immune system process
|
ADORA1, ALOX15, AXL, CDK6, CYP19A1, DUSP3, ERBB2, MMP12, PTPRS |
2.49817 |
|
[BP] GO:0032147 |
activation of protein kinase activity
|
ADORA1, ADRA2A, ADRA2C, EGFR, INSR, KIT, PTPN1, SRC |
2.48705 |
|
[BP] GO:0048869 |
cellular developmental process
|
ACHE, ADRB1, AXL, CBR1, CDC25B, CDK6, CYP1A1, EGFR, ERBB2, FABP4, FLT3, GLO1, KDR, KIT, MET, MMP2, MMP9, PTPRS, RORC, SMAD3, SRC, TEK, THRA, THRB, TOP2A |
2.48656 |
|
[BP] GO:0098502 |
DNA dephosphorylation
|
APEX1, POLB |
2.45961 |
|
[BP] GO:0032849 |
positive regulation of cellular pH reduction
|
CA2, CA7 |
2.45961 |
|
[BP] GO:0002520 |
None
|
CACNA1C, SMAD3 |
2.45961 |
|
[BP] GO:0014066 |
regulation of phosphatidylinositol 3-kinase signaling
|
EGFR, FLT3, KDR, KIT, TEK |
2.45511 |
|
[BP] GO:0010038 |
response to metal ion
|
ALOX15, CA2, CYP1A1, CYP1A2, EGFR, FABP4, KIT, MMP9 |
2.44836 |
|
[BP] GO:0008016 |
None
|
ADORA1, ADORA3, ADRB1, CACNA1C, CHRM2, THRA, THRB |
2.41508 |
|
[BP] GO:1901617 |
organic hydroxy compound biosynthetic process
|
AKR1B1, ALOX15, CYP19A1, DAO, PTAFR, TYR |
2.4146 |
|
[BP] GO:0051828 |
entry into other organism involved in symbiotic interaction
|
AXL, EGFR, HSPA1A, MET, SRC |
2.38322 |
|
[BP] GO:0051806 |
entry into cell of other organism involved in symbiotic interaction
|
AXL, EGFR, HSPA1A, MET, SRC |
2.38322 |
|
[BP] GO:0030260 |
entry into host cell
|
AXL, EGFR, HSPA1A, MET, SRC |
2.38322 |
|
[BP] GO:0044409 |
entry into host
|
AXL, EGFR, HSPA1A, MET, SRC |
2.38322 |
|
[BP] GO:0010676 |
None
|
INSR, PPARA, PTAFR, SRC |
2.37917 |
|
[BP] GO:0050994 |
None
|
ADORA1, ADRA2A, PPARA, THRA |
2.37917 |
|
[BP] GO:0043550 |
regulation of lipid kinase activity
|
FLT3, KIT, SRC, TEK |
2.37917 |
|
[BP] GO:0048732 |
gland development
|
CSNK2A1, CYP19A1, EGFR, INSR, SMAD3, THRA, TYR |
2.37126 |
|
[BP] GO:0050794 |
regulation of cellular process
|
ACHE, ADORA1, ADORA3, ADRA2A, ADRA2C, ADRB1, AKR1B1, ALOX15, APEX1, AURKB, AXL, CA1, CA2, CA7, CA9, CACNA1C, CDC25B, CDK6, CHRM2, CSNK2A1, CYP19A1, CYP1A1, CYP1B1, DUSP3, EGFR, ERBB2, F10, FABP3, FABP4, FLT3, GLO1, GPR35, HSPA1A, IGF1R, INSR, KDR, KIT, MET, MMP1, MMP12, MMP2, MMP9, NR1H4, NUAK1, PHF8, PIM1, POLA1, POLB, PPARA, PTAFR, PTPN1, PTPRS, RORC, SMAD3, SRC, TEK, THRA, THRB, TNKS, TNKS2, TOP2A, XDH |
2.36761 |
|
[BP] GO:0050678 |
None
|
CDK6, EGFR, ERBB2, KDR, MMP12, SMAD3, TEK, XDH |
2.36374 |
|
[BP] GO:0048534 |
hematopoietic or lymphoid organ development
|
FLT3, KDR, KIT, POLB, TEK, TYR |
2.3597 |
|
[BP] GO:0009755 |
hormone-mediated signaling pathway
|
NR1H4, PPARA, RORC, SRC, THRA, THRB |
2.3597 |
|
[BP] GO:1901699 |
cellular response to nitrogen compound
|
AKR1B1, APEX1, EGFR, IGF1R, INSR, MMP2, NR1H4, PTAFR, SRC |
2.3581 |
|
[BP] GO:0001952 |
regulation of cell-matrix adhesion
|
CDK6, KDR, SMAD3, SRC, TEK |
2.3581 |
|
[BP] GO:0032210 |
regulation of telomere maintenance via telomerase
|
AURKB, SRC, TNKS, TNKS2 |
2.3581 |
|
[BP] GO:0051893 |
regulation of focal adhesion assembly
|
KDR, SMAD3, SRC, TEK |
2.32991 |
|
[BP] GO:0090109 |
regulation of cell-substrate junction assembly
|
KDR, SMAD3, SRC, TEK |
2.32991 |
|
[BP] GO:0035588 |
None
|
ADORA1, ADORA3, PTAFR |
2.32991 |
|
[BP] GO:0071880 |
None
|
ADRA2A, ADRA2C, ADRB1 |
2.32991 |
|
[BP] GO:0044236 |
multicellular organism metabolic process
|
ADRB1, MMP1, MMP12, MMP2, MMP9 |
2.30766 |
|
[BP] GO:0010811 |
positive regulation of cell-substrate adhesion
|
ALOX15, CDK6, KDR, SMAD3, TEK |
2.30766 |
|
[BP] GO:0071241 |
cellular response to inorganic substance
|
ALOX15, CYP1A1, CYP1A2, EGFR, FABP4, MMP9 |
2.30374 |
|
[BP] GO:0051726 |
regulation of cell cycle
|
APEX1, AURKB, CDC25B, CDK6, CSNK2A1, CYP1A1, DUSP3, EGFR, HSPA1A, INSR, PIM1, SMAD3, SRC, TNKS, TOP2A |
2.30374 |
|
[BP] GO:0006721 |
terpenoid metabolic process
|
AKR1B10, CYP1A1, CYP1A2, CYP1B1, EGFR |
2.29202 |
|
[BP] GO:0046686 |
response to cadmium ion
|
CYP1A2, EGFR, KIT, MMP9 |
2.27885 |
|
[BP] GO:0042542 |
response to hydrogen peroxide
|
AKR1B1, APEX1, AXL, CYP1B1, SRC |
2.27654 |
|
[BP] GO:0006979 |
response to oxidative stress
|
AKR1B1, APEX1, AXL, CYP1B1, EGFR, HSPA1A, MMP9, SRC |
2.27209 |
|
[BP] GO:0051223 |
None
|
ACHE, ADRA2A, ADRA2C, CACNA1C, EGFR, ERBB2, MMP12, NR1H4, PTPN1, SMAD3, SRC, THRA |
2.26976 |
|
[BP] GO:0032101 |
regulation of response to external stimulus
|
ADORA1, CYP19A1, EGFR, FABP4, KDR, MET, MMP12, NR1H4, PPARA, PTPRS, SMAD3, TEK |
2.26573 |
|
[BP] GO:1903391 |
regulation of adherens junction organization
|
KDR, SMAD3, SRC, TEK |
2.25596 |
|
[BP] GO:0009894 |
regulation of catabolic process
|
ADORA1, ADRA2A, APEX1, CSNK2A1, EGFR, HSPA1A, INSR, KDR, MET, PPARA, PTPN1, SMAD3, THRA |
2.2444 |
|
[BP] GO:0009968 |
negative regulation of signal transduction
|
ADRA2A, DUSP3, EGFR, ERBB2, HSPA1A, IGF1R, MET, MMP12, MMP9, NR1H4, PTPN1, PTPRS, SMAD3, SRC, XDH |
2.24285 |
|
[BP] GO:1901654 |
None
|
AKR1B1, CA9, CSNK2A1, EGFR, PTAFR, SRC |
2.23654 |
|
[BP] GO:2001251 |
None
|
PHF8, SRC, TNKS, TNKS2, TOP2A |
2.23106 |
|
[BP] GO:1901652 |
response to peptide
|
AKR1B1, APEX1, FABP3, IGF1R, INSR, PPARA, SRC, TEK |
2.23077 |
|
[BP] GO:0001666 |
response to hypoxia
|
ADORA1, CYP1A1, MMP2, PPARA, SMAD3, SRC, TEK |
2.22671 |
|
[BP] GO:0035625 |
None
|
ADRA2A, ADRA2C |
2.2267 |
|
[BP] GO:0032811 |
None
|
ADRA2A, ADRA2C |
2.2267 |
|
[BP] GO:0070213 |
None
|
TNKS, TNKS2 |
2.2267 |
|
[BP] GO:0032847 |
regulation of cellular pH reduction
|
CA2, CA7 |
2.2267 |
|
[BP] GO:1901529 |
None
|
ABCB1, PTAFR |
2.2267 |
|
[BP] GO:0018894 |
dibenzo-p-dioxin metabolic process
|
CYP1A1, CYP1A2 |
2.2267 |
|
[BP] GO:0071407 |
cellular response to organic cyclic compound
|
APEX1, CYP1A1, CYP1B1, EGFR, FLT3, PTAFR, RORC, SRC |
2.22424 |
|
[BP] GO:0002791 |
None
|
ACHE, ADORA1, ADRA2A, ADRA2C, CACNA1C, EGFR, MMP12, NR1H4, SRC |
2.2187 |
|
[BP] GO:0070988 |
demethylation
|
APEX1, CYP1A1, CYP1A2, PHF8 |
2.21615 |
|
[BP] GO:0046883 |
regulation of hormone secretion
|
ADORA1, ADRA2A, ADRA2C, CACNA1C, CYP19A1, EGFR, NR1H4 |
2.19824 |
|
[BP] GO:0019219 |
regulation of nucleobase-containing compound metabolic process
|
ADORA3, ADRA2A, ADRB1, APEX1, AURKB, CA9, CSNK2A1, CYP1B1, EGFR, ERBB2, FABP4, GLO1, HSPA1A, IGF1R, INSR, KIT, MET, MMP12, NR1H4, PHF8, PIM1, POLA1, PPARA, PTAFR, PTPN1, RORC, SMAD3, SRC, THRA, THRB, TNKS, TNKS2, TOP2A |
2.19471 |
|
[BP] GO:0006805 |
xenobiotic metabolic process
|
CYP1A1, CYP1A2, CYP1B1, CYP2A13, RORC |
2.19393 |
|
[BP] GO:1904356 |
regulation of telomere maintenance via telomere lengthening
|
AURKB, SRC, TNKS, TNKS2 |
2.19332 |
|
[BP] GO:0019229 |
None
|
ADRA2A, ADRA2C, EGFR, PTAFR |
2.19332 |
|
[BP] GO:0071396 |
cellular response to lipid
|
AXL, CDK6, EGFR, FLT3, NR1H4, PTAFR, RORC, SRC |
2.19105 |
|
[BP] GO:1903530 |
regulation of secretion by cell
|
ACHE, ADORA1, ADRA2A, ADRA2C, CACNA1C, CYP19A1, EGFR, MMP12, NR1H4, PTAFR, SRC |
2.18787 |
|
[BP] GO:0051953 |
None
|
ADORA1, ADRA2A, ADRA2C |
2.18787 |
|
[BP] GO:0009404 |
toxin metabolic process
|
CYP1A1, CYP1A2, CYP1B1 |
2.18787 |
|
[BP] GO:0070301 |
cellular response to hydrogen peroxide
|
AKR1B1, APEX1, AXL, CYP1B1 |
2.17091 |
|
[BP] GO:0036293 |
response to decreased oxygen levels
|
ADORA1, CYP1A1, MMP2, PPARA, SMAD3, SRC, TEK |
2.16899 |
|
[BP] GO:0050793 |
regulation of developmental process
|
ADRA2C, ADRB1, AXL, CA2, CDK6, CYP1B1, EGFR, ERBB2, INSR, KDR, KIT, NR1H4, NUAK1, PIM1, PPARA, PTPRS, RORC, SMAD3, SRC, TEK, THRA, TNKS2, XDH |
2.16633 |
|
[BP] GO:0016042 |
lipid catabolic process
|
ADORA1, AKR1B10, CYP19A1, CYP1A2, CYP1B1, FABP3, FABP4 |
2.14119 |
|
[BP] GO:0010810 |
regulation of cell-substrate adhesion
|
ALOX15, CDK6, KDR, SMAD3, SRC, TEK |
2.14015 |
|
[BP] GO:0051894 |
None
|
KDR, SMAD3, TEK |
2.14015 |
|
[BP] GO:0071875 |
None
|
ADRA2A, ADRA2C, ADRB1 |
2.14015 |
|
[BP] GO:1903409 |
reactive oxygen species biosynthetic process
|
CYP1A1, CYP1A2, CYP1B1 |
2.14015 |
|
[BP] GO:0097237 |
cellular response to toxic substance
|
AKR1B1, APEX1, AXL, CYP1B1, KDR |
2.10924 |
|
[BP] GO:0070201 |
None
|
ACHE, ADRA2A, ADRA2C, CACNA1C, EGFR, ERBB2, MMP12, NR1H4, PTPN1, SMAD3, SRC, THRA |
2.10398 |
|
[BP] GO:2000573 |
positive regulation of DNA biosynthetic process
|
AURKB, SRC, TNKS, TNKS2 |
2.10398 |
|
[BP] GO:0010675 |
None
|
INSR, PPARA, PTAFR, RORC, SRC |
2.0956 |
|
[BP] GO:0045787 |
positive regulation of cell cycle
|
APEX1, AURKB, CDC25B, CYP1A1, DUSP3, EGFR, INSR, SRC |
2.09016 |
|
[BP] GO:0001775 |
cell activation
|
ADRA2A, ADRA2C, ALOX5, AXL, EGFR, FLT3, HSPA1A, KIT, MMP9, PTAFR, RORC, SMAD3, SRC |
2.08495 |
|
[BP] GO:0030574 |
collagen catabolic process
|
MMP1, MMP12, MMP2, MMP9 |
2.08319 |
|
[BP] GO:0071229 |
cellular response to acid chemical
|
EGFR, KDR, MMP2, NR1H4, PTAFR, SRC |
2.07972 |
|
[BP] GO:0032102 |
negative regulation of response to external stimulus
|
ADORA1, CYP19A1, NR1H4, PPARA, PTPRS, SMAD3, TEK |
2.07198 |
|
[BP] GO:0014068 |
positive regulation of phosphatidylinositol 3-kinase signaling
|
FLT3, KDR, KIT, TEK |
2.0617 |
|
[BP] GO:1904353 |
regulation of telomere capping
|
AURKB, TNKS, TNKS2 |
2.05574 |
|
[BP] GO:1903393 |
None
|
KDR, SMAD3, TEK |
2.05574 |
|
[BP] GO:0035624 |
None
|
ADRA2A, ADRA2C |
2.05574 |
|
[BP] GO:0098501 |
polynucleotide dephosphorylation
|
APEX1, POLB |
2.05574 |
|
[BP] GO:0060509 |
None
|
THRA, THRB |
2.05574 |
|
[BP] GO:0002318 |
myeloid progenitor cell differentiation
|
FLT3, KIT |
2.05574 |
|
[BP] GO:0014060 |
None
|
ADRA2A, ADRA2C |
2.05574 |
|
[BP] GO:0006720 |
isoprenoid metabolic process
|
AKR1B10, CYP1A1, CYP1A2, CYP1B1, EGFR |
2.05069 |
|
[BP] GO:0010634 |
positive regulation of epithelial cell migration
|
KDR, MET, MMP9, SRC, TEK |
2.05069 |
|
[BP] GO:0006694 |
steroid biosynthetic process
|
AKR1B1, CYP19A1, HSD11B1, HSD17B1, HSD17B2 |
2.03554 |
|
[BP] GO:0044089 |
positive regulation of cellular component biogenesis
|
ALOX15, HSPA1A, KDR, KIT, MET, MMP1, SMAD3, SRC, TEK |
2.03345 |
|
[BP] GO:0045913 |
None
|
INSR, PPARA, PTAFR, SRC |
2.02815 |
|
[BP] GO:0051047 |
None
|
ACHE, ADORA1, CYP19A1, EGFR, MMP12, NR1H4, PTAFR, SRC |
2.02782 |
|
[BP] GO:1904357 |
None
|
SRC, TNKS, TNKS2 |
2.02237 |
|
[BP] GO:0048660 |
regulation of smooth muscle cell proliferation
|
AKR1B1, EGFR, MMP2, MMP9, PTAFR |
2.01282 |
|
[BP] GO:0042180 |
None
|
AKR1B1, AKR1B10, CYP19A1, GLO1 |
2.01173 |
|
[BP] GO:0009889 |
regulation of biosynthetic process
|
ADORA3, ADRA2A, ADRB1, APEX1, AURKB, CA9, CSNK2A1, CYP1B1, EGFR, ERBB2, FABP3, FABP4, GLO1, HSPA1A, IGF1R, INSR, KDR, KIT, MET, MMP12, NR1H4, PHF8, PIM1, POLA1, PPARA, PTAFR, RORC, SMAD3, SRC, THRA, THRB, TNKS, TNKS2, TOP2A |
2.00895 |
|
[CC] GO:0016323 |
basolateral plasma membrane
|
ADORA1, ADRA2A, CA2, CA4, CA9, EGFR, ERBB2, TEK |
3.87356 |
|
[CC] GO:0044459 |
plasma membrane part
|
ABCB1, ADORA1, ADORA3, ADRA2A, ADRA2C, ADRB1, ALOX15, AXL, CA2, CA4, CA9, CACNA1C, CHRM2, DUSP3, EGFR, ERBB2, F10, FLT3, GPR35, IGF1R, INSR, KDR, KIT, MET, PTAFR, PTPRS, SRC, TEK |
3.73349 |
|
[CC] GO:0044444 |
cytoplasmic part
|
ACHE, ADORA1, ADRA2C, ADRB1, AKR1B1, AKR1B10, ALOX15, ALOX5, APEX1, AURKB, CA1, CA2, CA4, CA7, CACNA1C, CBR1, CDC25B, CDK6, CHRM2, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, DAO, DUSP3, EGFR, ERBB2, F10, FABP3, FABP4, FLT3, GLO1, HSD11B1, HSD17B1, HSD17B2, HSPA1A, INSR, KDR, KIT, MMP2, MMP9, PIM1, POLA1, PTAFR, PTPN1, PTPRS, SMAD3, SRC, TBXAS1, THRA, TNKS, TNKS2, TOP1, TOP2A, TYR, XDH |
3.13222 |
|
[CC] GO:0005886 |
plasma membrane
|
ABCB1, ACHE, ADORA1, ADORA3, ADRA2A, ADRA2C, ADRB1, ALOX15, AXL, CA12, CA14, CA2, CA4, CA9, CACNA1C, CHRM2, CSNK2A1, EGFR, ERBB2, F10, FLT3, GLO1, GPR35, IGF1R, INSR, KDR, KIT, MET, MMP2, PIM1, PTAFR, PTPN1, PTPRS, SMAD3, SRC, TEK |
3.01096 |
|
[CC] GO:0009330 |
None
|
TOP1, TOP2A |
2.87874 |
|
[CC] GO:0031226 |
intrinsic component of plasma membrane
|
ADORA1, ADORA3, ADRA2A, ADRA2C, ADRB1, AXL, CA4, CHRM2, F10, FLT3, GPR35, IGF1R, INSR, KDR, MET, PTAFR, PTPRS, TEK |
2.72385 |
|
[CC] GO:0016020 |
membrane
|
ABCB1, ACHE, ADORA1, ADORA3, ADRA2A, ADRA2C, ADRB1, ALOX15, ALOX5, AXL, CA12, CA14, CA2, CA4, CA9, CACNA1C, CHRM2, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, DAO, EGFR, ERBB2, F10, FLT3, GLO1, GPR35, HSD11B1, HSD17B2, IGF1R, INSR, KDR, KIT, MET, MMP2, PHF8, PIM1, PTAFR, PTPN1, PTPRS, SMAD3, SRC, TBXAS1, TEK, TNKS, TNKS2, TYR |
2.67155 |
|
[CC] GO:0044454 |
None
|
APEX1, AURKB, CSNK2A1, NR1H4, POLA1, SMAD3, THRB, TNKS, TNKS2, TOP1 |
2.3597 |
|
[CC] GO:0044464 |
cell part
|
ABCB1, ACHE, ADORA1, ADORA3, ADRA2A, ADRA2C, ADRB1, AKR1B1, AKR1B10, ALOX15, ALOX5, APEX1, AURKB, AXL, CA1, CA12, CA14, CA2, CA4, CA7, CA9, CACNA1C, CBR1, CDC25B, CDK6, CHRM2, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, DAO, DUSP3, EGFR, ERBB2, F10, FABP3, FABP4, FLT3, GLO1, GPR35, HSD11B1, HSD17B1, HSD17B2, HSPA1A, IGF1R, INSR, KDR, KIT, MET, MMP12, MMP2, MMP9, NR1H4, NUAK1, PHF8, PIM1, POLA1, POLB, PPARA, PTAFR, PTPN1, PTPRS, RORC, SMAD3, SRC, TBXAS1, TEK, THRA, THRB, TNKS, TNKS2, TOP1, TOP2A, TUBB3, TYR, XDH |
2.11753 |
|
[CC] GO:0098590 |
plasma membrane region
|
ABCB1, ADORA1, ADRA2A, CA2, CA4, CA9, CHRM2, EGFR, ERBB2, INSR, MET, SRC, TEK |
2.02565 |
|
[CC] GO:0005887 |
integral component of plasma membrane
|
ADORA1, ADORA3, ADRA2A, ADRA2C, ADRB1, AXL, CHRM2, FLT3, GPR35, IGF1R, INSR, KDR, MET, PTAFR, PTPRS, TEK |
2.02565 |
|
[MF] GO:0043167 |
ion binding
|
ABCB1, ACHE, ALOX15, ALOX5, APEX1, AURKB, AXL, CA1, CA12, CA14, CA2, CA4, CA7, CA9, CACNA1C, CDK6, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, DAO, EGFR, ERBB2, F10, FABP3, FABP4, FLT3, GLO1, HSD17B1, HSPA1A, IGF1R, INSR, KDR, KIT, MET, MMP1, MMP12, MMP2, MMP9, NR1H4, NUAK1, PHF8, PIM1, POLA1, POLB, PPARA, PTAFR, PTPN1, PTPRS, RORC, SMAD3, SRC, TBXAS1, TEK, THRA, THRB, TNKS, TNKS2, TOP1, TOP2A, TUBB3, TYR, XDH |
15.7014 |
|
[MF] GO:0046914 |
transition metal ion binding
|
ALOX15, ALOX5, CA1, CA12, CA2, CA4, CA7, CA9, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, GLO1, MMP1, MMP12, MMP2, MMP9, NR1H4, PHF8, PIM1, PPARA, PTPN1, RORC, SMAD3, TBXAS1, THRA, THRB, TNKS, TYR, XDH |
15.129 |
|
[MF] GO:0003824 |
catalytic activity
|
ABCB1, ACHE, ADORA1, AKR1B1, AKR1B10, ALOX15, ALOX5, APEX1, AURKB, AXL, CA1, CA12, CA14, CA2, CA4, CA7, CA9, CBR1, CDC25B, CDK6, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, DAO, DUSP3, EGFR, ERBB2, F10, FLT3, GLO1, HSD11B1, HSD17B1, HSD17B2, HSPA1A, IGF1R, INSR, KDR, KIT, MET, MMP1, MMP12, MMP2, MMP9, NUAK1, PHF8, PIM1, POLA1, POLB, PTPN1, PTPRS, SRC, TBXAS1, TEK, TNKS, TNKS2, TOP1, TOP2A, TUBB3, TYR, XDH |
15.1159 |
|
[MF] GO:0004714 |
transmembrane receptor protein tyrosine kinase activity
|
AXL, EGFR, ERBB2, FLT3, IGF1R, INSR, KDR, KIT, MET, TEK |
9.63209 |
|
[MF] GO:0004089 |
carbonate dehydratase activity
|
CA1, CA12, CA14, CA2, CA4, CA7, CA9 |
9.56463 |
|
[MF] GO:0019199 |
transmembrane receptor protein kinase activity
|
AXL, EGFR, ERBB2, FLT3, IGF1R, INSR, KDR, KIT, MET, TEK |
8.7635 |
|
[MF] GO:0016491 |
oxidoreductase activity
|
AKR1B1, AKR1B10, ALOX15, ALOX5, APEX1, CBR1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, DAO, HSD11B1, HSD17B1, HSD17B2, PHF8, TBXAS1, TYR, XDH |
7.88248 |
|
[MF] GO:0016835 |
carbon-oxygen lyase activity
|
APEX1, CA1, CA12, CA14, CA2, CA4, CA7, CA9, POLB |
7.62773 |
|
[MF] GO:0005506 |
iron ion binding
|
ALOX15, ALOX5, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, PHF8, TBXAS1, XDH |
7.38484 |
|
[MF] GO:0008270 |
zinc ion binding
|
CA1, CA12, CA2, CA4, CA7, CA9, GLO1, MMP1, MMP12, MMP2, MMP9, NR1H4, PHF8, PPARA, PTPN1, RORC, SMAD3, THRA, THRB, TNKS |
7.28552 |
|
[MF] GO:0043169 |
cation binding
|
ACHE, ALOX15, ALOX5, APEX1, AURKB, CA1, CA12, CA14, CA2, CA4, CA7, CA9, CACNA1C, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, F10, GLO1, KIT, MMP1, MMP12, MMP2, MMP9, NR1H4, NUAK1, PHF8, PIM1, POLA1, POLB, PPARA, PTPN1, RORC, SMAD3, TBXAS1, THRA, THRB, TNKS, TNKS2, TOP2A, TYR, XDH |
7.22587 |
|
[MF] GO:0008144 |
drug binding
|
ABCB1, ACHE, AURKB, AXL, CDK6, CHRM2, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, EGFR, ERBB2, FLT3, HSPA1A, IGF1R, INSR, KDR, KIT, MET, NUAK1, PIM1, PPARA, SRC, TEK, TOP1, TOP2A |
7.20652 |
|
[MF] GO:0004716 |
signal transducer, downstream of receptor, with protein tyrosine kinase activity
|
EGFR, ERBB2, INSR, KDR, KIT |
7.11633 |
|
[MF] GO:0046872 |
metal ion binding
|
ALOX15, ALOX5, APEX1, AURKB, CA1, CA12, CA14, CA2, CA4, CA7, CA9, CACNA1C, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, F10, GLO1, KIT, MMP1, MMP12, MMP2, MMP9, NR1H4, NUAK1, PHF8, PIM1, POLA1, POLB, PPARA, PTPN1, RORC, SMAD3, TBXAS1, THRA, THRB, TNKS, TNKS2, TOP2A, TYR, XDH |
6.97907 |
|
[MF] GO:0004713 |
protein tyrosine kinase activity
|
AXL, EGFR, ERBB2, FLT3, IGF1R, INSR, KDR, KIT, MET, SRC, TEK |
6.9518 |
|
[MF] GO:0016712 |
oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen
|
CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6 |
6.4488 |
|
[MF] GO:0004672 |
protein kinase activity
|
AURKB, AXL, CDK6, CSNK2A1, EGFR, ERBB2, FLT3, IGF1R, INSR, KDR, KIT, MET, NUAK1, PIM1, SRC, TEK, TOP1 |
6.38071 |
|
[MF] GO:0016836 |
hydro-lyase activity
|
CA1, CA12, CA14, CA2, CA4, CA7, CA9 |
6.05915 |
|
[MF] GO:0016829 |
lyase activity
|
APEX1, CA1, CA12, CA14, CA2, CA4, CA7, CA9, GLO1, POLB |
5.88269 |
|
[MF] GO:0038023 |
signaling receptor activity
|
ADORA1, ADORA3, ADRA2A, ADRA2C, ADRB1, AXL, CHRM2, EGFR, ERBB2, FLT3, GPR35, IGF1R, INSR, KDR, KIT, MET, NR1H4, PPARA, PTAFR, RORC, TEK, THRA, THRB |
5.87683 |
|
[MF] GO:0004497 |
monooxygenase activity
|
CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, TBXAS1, TYR |
5.80255 |
|
[MF] GO:0016705 |
oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen
|
CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, PHF8, TBXAS1, TYR |
5.43784 |
|
[MF] GO:0060089 |
molecular transducer activity
|
ADORA1, ADORA3, ADRA2A, ADRA2C, ADRB1, AXL, CDK6, CHRM2, EGFR, ERBB2, FLT3, GPR35, IGF1R, INSR, KDR, KIT, MET, NR1H4, PPARA, PTAFR, RORC, TEK, THRA, THRB |
5.42043 |
|
[MF] GO:0016773 |
phosphotransferase activity, alcohol group as acceptor
|
AURKB, AXL, CDK6, CSNK2A1, EGFR, ERBB2, FLT3, IGF1R, INSR, KDR, KIT, MET, NUAK1, PIM1, SRC, TEK, TOP1 |
5.40021 |
|
[MF] GO:0016772 |
transferase activity, transferring phosphorus-containing groups
|
AURKB, AXL, CDK6, CSNK2A1, EGFR, ERBB2, FLT3, IGF1R, INSR, KDR, KIT, MET, NUAK1, PIM1, POLA1, POLB, SRC, TEK, TOP1 |
5.32683 |
|
[MF] GO:0070330 |
aromatase activity
|
CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13 |
5.17497 |
|
[MF] GO:0043168 |
anion binding
|
ABCB1, ALOX15, AURKB, AXL, CDK6, CSNK2A1, DAO, EGFR, ERBB2, F10, FABP3, FABP4, FLT3, HSD17B1, HSPA1A, IGF1R, INSR, KDR, KIT, MET, NR1H4, NUAK1, PIM1, PTAFR, PTPRS, SRC, TEK, TOP1, TOP2A, TUBB3, XDH |
5.07654 |
|
[MF] GO:0004872 |
receptor activity
|
ADORA1, ADORA3, ADRA2A, ADRA2C, ADRB1, AXL, CHRM2, EGFR, ERBB2, FLT3, GPR35, IGF1R, INSR, KDR, KIT, MET, NR1H4, PPARA, PTAFR, RORC, TEK, THRA, THRB |
5.07654 |
|
[MF] GO:0036094 |
small molecule binding
|
ABCB1, ADORA1, AURKB, AXL, CDK6, CSNK2A1, DAO, EGFR, ERBB2, FABP3, FABP4, FLT3, HSD17B1, HSPA1A, IGF1R, INSR, KDR, KIT, MET, NR1H4, NUAK1, PIM1, POLA1, SRC, TEK, TOP1, TOP2A, TUBB3, XDH |
4.99934 |
|
[MF] GO:0020037 |
heme binding
|
CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, SRC, TBXAS1 |
4.98163 |
|
[MF] GO:0004871 |
signal transducer activity
|
ADORA1, ADORA3, ADRA2A, ADRA2C, ADRB1, AXL, CHRM2, EGFR, ERBB2, FLT3, GPR35, IGF1R, INSR, KDR, KIT, MET, NR1H4, PPARA, PTAFR, RORC, SMAD3, TEK, THRA, THRB |
4.97243 |
|
[MF] GO:0042562 |
hormone binding
|
ACHE, EGFR, HSD17B1, IGF1R, INSR, THRA, THRB |
4.96734 |
|
[MF] GO:0016301 |
kinase activity
|
AURKB, AXL, CDK6, CSNK2A1, EGFR, ERBB2, FLT3, IGF1R, INSR, KDR, KIT, MET, NUAK1, PIM1, SRC, TEK, TOP1 |
4.95261 |
|
[MF] GO:0044877 |
macromolecular complex binding
|
ACHE, ADORA1, ADRA2A, APEX1, CSNK2A1, EGFR, FLT3, IGF1R, INSR, KDR, MMP12, MMP9, PIM1, PPARA, PTPN1, SMAD3, SRC, THRA |
4.83017 |
|
[MF] GO:0046906 |
tetrapyrrole binding
|
CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, SRC, TBXAS1 |
4.77187 |
|
[MF] GO:0032403 |
protein complex binding
|
ACHE, ADORA1, ADRA2A, APEX1, EGFR, FLT3, IGF1R, INSR, KDR, MMP12, MMP9, PPARA, PTPN1, SMAD3, SRC, THRA |
4.66994 |
|
[MF] GO:0140096 |
catalytic activity, acting on a protein
|
AURKB, AXL, CDC25B, CDK6, CSNK2A1, DUSP3, EGFR, ERBB2, F10, FLT3, IGF1R, INSR, KDR, KIT, MET, MMP1, MMP12, MMP2, MMP9, NUAK1, PHF8, PIM1, PTPN1, PTPRS, SRC, TEK, TOP1 |
4.17928 |
|
[MF] GO:0000166 |
nucleotide binding
|
ABCB1, AURKB, AXL, CDK6, CSNK2A1, DAO, EGFR, ERBB2, FLT3, HSD17B1, HSPA1A, IGF1R, INSR, KDR, KIT, MET, NUAK1, PIM1, POLA1, SRC, TEK, TOP1, TOP2A, TUBB3, XDH |
4.01641 |
|
[MF] GO:1901265 |
nucleoside phosphate binding
|
ABCB1, AURKB, AXL, CDK6, CSNK2A1, DAO, EGFR, ERBB2, FLT3, HSD17B1, HSPA1A, IGF1R, INSR, KDR, KIT, MET, NUAK1, PIM1, POLA1, SRC, TEK, TOP1, TOP2A, TUBB3, XDH |
4.01641 |
|
[MF] GO:0048037 |
cofactor binding
|
CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, DAO, HSD17B1, POLA1, SRC, TBXAS1, XDH |
4.01641 |
|
[MF] GO:0005057 |
signal transducer activity, downstream of receptor
|
ADRB1, EGFR, ERBB2, INSR, KDR, KIT, SMAD3 |
3.99115 |
|
[MF] GO:0019825 |
oxygen binding
|
CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13 |
3.82328 |
|
[MF] GO:0097367 |
carbohydrate derivative binding
|
ABCB1, ADORA1, AURKB, AXL, CDK6, CSNK2A1, EGFR, ERBB2, FLT3, HSPA1A, IGF1R, INSR, KDR, KIT, MET, NUAK1, PIM1, POLA1, PTAFR, PTPRS, SRC, TEK, TOP1, TOP2A, TUBB3 |
3.80813 |
|
[MF] GO:0016614 |
oxidoreductase activity, acting on CH-OH group of donors
|
AKR1B1, AKR1B10, CBR1, HSD11B1, HSD17B1, HSD17B2, XDH |
3.72913 |
|
[MF] GO:0005524 |
ATP binding
|
ABCB1, AURKB, AXL, CDK6, CSNK2A1, EGFR, ERBB2, FLT3, HSPA1A, IGF1R, INSR, KDR, KIT, MET, NUAK1, PIM1, SRC, TEK, TOP1, TOP2A |
3.68944 |
|
[MF] GO:0098531 |
transcription factor activity, direct ligand regulated sequence-specific DNA binding
|
NR1H4, PPARA, RORC, THRA, THRB |
3.67529 |
|
[MF] GO:0004879 |
nuclear receptor activity
|
NR1H4, PPARA, RORC, THRA, THRB |
3.67529 |
|
[MF] GO:0004887 |
None
|
NR1H4, THRA, THRB |
3.56806 |
|
[MF] GO:0032559 |
adenyl ribonucleotide binding
|
ABCB1, AURKB, AXL, CDK6, CSNK2A1, EGFR, ERBB2, FLT3, HSPA1A, IGF1R, INSR, KDR, KIT, MET, NUAK1, PIM1, SRC, TEK, TOP1, TOP2A |
3.55827 |
|
[MF] GO:0097159 |
organic cyclic compound binding
|
ABCB1, ADORA1, ADRA2A, ADRA2C, ADRB1, APEX1, AURKB, AXL, CDK6, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, DAO, EGFR, ERBB2, FLT3, HSD17B1, HSPA1A, IGF1R, INSR, KDR, KIT, MET, MMP12, NR1H4, NUAK1, PIM1, POLA1, POLB, PPARA, PTPN1, RORC, SMAD3, SRC, TBXAS1, TEK, THRA, THRB, TOP1, TOP2A, TUBB3, XDH |
3.53209 |
|
[MF] GO:0030554 |
adenyl nucleotide binding
|
ABCB1, AURKB, AXL, CDK6, CSNK2A1, EGFR, ERBB2, FLT3, HSPA1A, IGF1R, INSR, KDR, KIT, MET, NUAK1, PIM1, SRC, TEK, TOP1, TOP2A |
3.53209 |
|
[MF] GO:0099600 |
transmembrane receptor activity
|
ADORA1, ADORA3, ADRA2A, ADRA2C, ADRB1, AXL, CHRM2, EGFR, ERBB2, FLT3, GPR35, IGF1R, INSR, KDR, KIT, MET, PTAFR, TEK |
3.52051 |
|
[MF] GO:0004888 |
transmembrane signaling receptor activity
|
ADORA1, ADORA3, ADRA2A, ADRA2C, ADRB1, AXL, CHRM2, EGFR, ERBB2, FLT3, GPR35, IGF1R, INSR, KDR, KIT, MET, PTAFR, TEK |
3.52051 |
|
[MF] GO:0051379 |
None
|
ADRA2A, ADRA2C, ADRB1 |
3.40537 |
|
[MF] GO:0003707 |
steroid hormone receptor activity
|
NR1H4, PPARA, RORC, THRA, THRB |
3.34214 |
|
[MF] GO:0019899 |
enzyme binding
|
ADRA2A, ADRB1, AURKB, CDC25B, CYP1A1, CYP1A2, CYP2A6, DUSP3, EGFR, ERBB2, HSPA1A, KIT, MET, POLA1, POLB, PPARA, PTAFR, PTPN1, SMAD3, SRC, TEK, THRB, TNKS2, TOP2A |
3.30777 |
|
[MF] GO:0016616 |
oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
|
AKR1B1, AKR1B10, CBR1, HSD11B1, HSD17B1, HSD17B2 |
3.05562 |
|
[MF] GO:0035639 |
purine ribonucleoside triphosphate binding
|
ABCB1, AURKB, AXL, CDK6, CSNK2A1, EGFR, ERBB2, FLT3, HSPA1A, IGF1R, INSR, KDR, KIT, MET, NUAK1, PIM1, SRC, TEK, TOP1, TOP2A, TUBB3 |
3.04461 |
|
[MF] GO:0008395 |
steroid hydroxylase activity
|
CYP19A1, CYP1A1, CYP2A13, CYP2A6 |
3.01096 |
|
[MF] GO:0032555 |
purine ribonucleotide binding
|
ABCB1, AURKB, AXL, CDK6, CSNK2A1, EGFR, ERBB2, FLT3, HSPA1A, IGF1R, INSR, KDR, KIT, MET, NUAK1, PIM1, SRC, TEK, TOP1, TOP2A, TUBB3 |
2.91784 |
|
[MF] GO:0017076 |
purine nucleotide binding
|
ABCB1, AURKB, AXL, CDK6, CSNK2A1, EGFR, ERBB2, FLT3, HSPA1A, IGF1R, INSR, KDR, KIT, MET, NUAK1, PIM1, SRC, TEK, TOP1, TOP2A, TUBB3 |
2.8808 |
|
[MF] GO:0019838 |
growth factor binding
|
EGFR, ERBB2, IGF1R, INSR, KDR, TEK |
2.8796 |
|
[MF] GO:0032553 |
ribonucleotide binding
|
ABCB1, AURKB, AXL, CDK6, CSNK2A1, EGFR, ERBB2, FLT3, HSPA1A, IGF1R, INSR, KDR, KIT, MET, NUAK1, PIM1, SRC, TEK, TOP1, TOP2A, TUBB3 |
2.87874 |
|
[MF] GO:0008389 |
None
|
CYP2A13, CYP2A6 |
2.87874 |
|
[MF] GO:1901363 |
heterocyclic compound binding
|
ABCB1, ADORA1, APEX1, AURKB, AXL, CDK6, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, DAO, EGFR, ERBB2, FLT3, HSD17B1, HSPA1A, IGF1R, INSR, KDR, KIT, MET, MMP12, NR1H4, NUAK1, PIM1, POLA1, POLB, PPARA, PTPN1, RORC, SMAD3, SRC, TBXAS1, TEK, THRA, THRB, TOP1, TOP2A, TUBB3, XDH |
2.63506 |
|
[MF] GO:0004935 |
None
|
ADRA2A, ADRA2C, ADRB1 |
2.57992 |
|
[MF] GO:0046982 |
protein heterodimerization activity
|
ADORA1, ADRA2A, ADRA2C, ADRB1, AXL, EGFR, ERBB2, SMAD3, TOP2A, TYR |
2.56659 |
|
[MF] GO:0004938 |
None
|
ADRA2A, ADRA2C |
2.45961 |
|
[MF] GO:0031690 |
None
|
ADRA2A, ADRA2C, ADRB1 |
2.44122 |
|
[MF] GO:0019902 |
phosphatase binding
|
EGFR, ERBB2, MET, PPARA, PTPN1, SMAD3 |
2.38632 |
|
[MF] GO:1901338 |
None
|
ADRA2A, ADRA2C, ADRB1 |
2.32991 |
|
[MF] GO:0019900 |
None
|
ADRA2A, AURKB, CDC25B, DUSP3, EGFR, POLA1, PTAFR, PTPN1, SMAD3, SRC, TOP2A |
2.2839 |
|
[MF] GO:0008227 |
None
|
ADRA2A, ADRA2C, ADRB1, CHRM2 |
2.25596 |
|
[MF] GO:0032795 |
None
|
ADORA1, ADRA2A |
2.2267 |
|
[MF] GO:0019901 |
None
|
ADRA2A, CDC25B, DUSP3, EGFR, POLA1, PTAFR, PTPN1, SMAD3, SRC, TOP2A |
2.12993 |
|
[MF] GO:0005518 |
collagen binding
|
ACHE, MMP12, MMP9, SMAD3 |
2.12625 |
|
[MF] GO:0035586 |
None
|
ADORA1, ADORA3, PTAFR |
2.09472 |
|
[MF] GO:0046934 |
phosphatidylinositol-4,5-bisphosphate 3-kinase activity
|
EGFR, ERBB2, KIT, MET |
2.0617 |
|
[MF] GO:0043559 |
insulin binding
|
IGF1R, INSR |
2.05574 |
|
[MF] GO:0051380 |
None
|
ADRA2A, ADRB1 |
2.05574 |
|
[MF] GO:0031694 |
None
|
ADRA2C, ADRB1 |
2.05574 |
|
[MF] GO:0046983 |
protein dimerization activity
|
ACHE, ADORA1, ADRA2A, ADRA2C, ADRB1, AXL, DAO, EGFR, ERBB2, FLT3, KIT, SMAD3, TOP2A, TYR, XDH |
2.02818 |
|
[MF] GO:0033764 |
steroid dehydrogenase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
|
HSD11B1, HSD17B1, HSD17B2 |
2.02237 |
|
[MF] GO:0052813 |
phosphatidylinositol bisphosphate kinase activity
|
EGFR, ERBB2, KIT, MET |
2.01173 |
