Component: Vitex trifolia 蔓荆子


Description of the Component

Component ID
TCMH1432
Latin Name
Vitex trifolia
English Name
Threeleaf chastetree fruit
Chinese Pinyin Name
Man Jing Zi
中文名
蔓荆子
TCM Properties
Minor cold,Pungent,Bitter
TCM Meridians
Bladder,Stomach,Liver
Therapeutic Class English
For relieving exterior syndrome
Therapeutic Class Chinese
解表
Functions
dispel wind-heat from the head and eyes
Toxicity
NA
Geo-authentic habitats (道地产区)
Shandong Province
Reference
Chinese Pharmacopoeia (2015)
Barcode ID
ITSAO4721-14
Barcode Source
BOLDSYSTEMS

TCM Prescriptions with the Component

Prescription ID Prescription English Name Prescription Chinese Name
TCMF7260 益气聪明汤
TCMF1452 Boyun Tuiyi Pills 拨云退翳丸
TCMF2635 Boyun Tuiyi Pills 拨云退翳丸
TCMF1920 Decoction of Notopterygium for Rheumatism 羌活胜湿汤
TCMFx3418 Die Da Wan Hua You 跌打万花油
TCMF3940 Fu Ke Yang Kun Pills 妇科养坤丸
TCMF544 Fu Ke Yang Kun Pills 妇科养坤丸
TCMF3996 Huan Gu Pills 换骨丸
TCMF994 Huang Lian Shang Qing Capsule 黄连上清胶囊
TCMF157 Huang Lian Shang Qing Granules 黄连上清颗粒
TCMF4079 Huang Lian Shang Qing Pills 黄连上清丸
TCMF993 Huang Lian Shang Qing Tablet 黄连上清片
TCMF4072 Huang Lian Shang Qing Tablets 黄连上清片
TCMFx4719 Jia Wei Gan Mao Pills 加味感冒丸
TCMF4347 Jing Zhi Niu Huang Jie Du Tablets 京制牛黄解毒片
TCMFx4862 Luo Fu Shan Bai Cao You 罗浮山百草油
TCMF4504 Ming Mu Ji Li Pills 明目蒺藜丸
TCMF2226 Powder of Two Effective Ingredients with Cyperus Peel and Perilla Leaf 加味香苏散
TCMFx226 Qi Wei Ke Teng Zi Pills 七味榼藤子丸
TCMF2839 Qiang Huo Sheng Shi Decoction 羌活胜湿汤
TCMF7382 Qiang Huo Sheng Shi Decoction 羌活胜湿汤
TCMF5443 Qing Nao Fu Shen Oral Liquid 清脑复神液
TCMF2855 Qing Shang Juan Tong Decoction 清上蠲痛汤
TCMFx1986 Qiwei Ketengzi Pills 七味榼藤子丸
TCMF257 Tian Ju Nao An Capsule 天菊脑安胶囊
TCMF5603 Wu Zhi Di Xian Jin Sui Ointment 五芝地仙金髓膏
TCMF6044 Xin Fang Bi Yan Capsules 辛芳鼻炎胶囊
TCMF6242 Xiong Ju Shang Qing Granules 芎菊上清颗粒
TCMF127 Xiong Ju Shang Qing Pills 芎菊上清丸
TCMF6257 Xiong Ju Shang Qing Pills 芎菊上清丸
TCMF128 Xiong Ju Shang Qing Tablets 芎菊上清片
TCMF6249 Xiong Ju Shang Qing Tablets 芎菊上清片
TCMF6566 Yi Qi Cong Ming Pills 益气聪明丸
TCMF1129 Zhang Yan Ming Tablet 障眼明片
TCMF6040 Zhang Yan Ming Tablets 障眼明片

Targeted Human Proteins by the Ingredient of Component

Target ID Gene Symbol Target Name Target Class Uniprot ID
TCMT1 EHMT2 Histone-lysine N-methyltransferase, H3 lysine-9 specific 3 Transferase Q96KQ7
TCMT100 TTR Transthyretin Unclassified P02766
TCMT101 PTPN1 Protein-tyrosine phosphatase 1B Hydrolase P18031
TCMT102 ACP1 Low molecular weight phosphotyrosine protein phosphatase Hydrolase P24666
TCMT103 PTPRF Receptor-type tyrosine-protein phosphatase F (LAR) Hydrolase P10586
TCMT11 HIF1A Hypoxia-inducible factor 1 alpha Transcription factor Q16665
TCMT112 ADORA3 Adenosine A3 receptor GPCR P0DMS8
TCMT125 GBA Beta-glucocerebrosidase Hydrolase P04062
TCMT126 TERT Telomerase reverse transcriptase Transferase O14746
TCMT127 PARP1 Poly [ADP-ribose] polymerase-1 Transferase P09874
TCMT128 TNKS2 Tankyrase-2 Transferase Q9H2K2
TCMT129 TNKS Tankyrase-1 Transferase O95271
TCMT130 ALOX5 Arachidonate 5-lipoxygenase Oxidoreductase P09917
TCMT131 ACHE Acetylcholinesterase Hydrolase P22303
TCMT132 BCHE Butyrylcholinesterase Hydrolase P06276
TCMT133 CA1 Carbonic anhydrase I Lyase P00915
TCMT134 CA2 Carbonic anhydrase II Lyase P00918
TCMT135 CA14 Carbonic anhydrase XIV Lyase Q9ULX7
TCMT136 CA12 Carbonic anhydrase XII Lyase O43570
TCMT137 CA9 Carbonic anhydrase IX Lyase Q16790
TCMT138 CA7 Carbonic anhydrase VII Lyase P43166
TCMT139 CA6 Carbonic anhydrase VI Lyase P23280
TCMT140 CA5B Carbonic anhydrase VB Lyase Q9Y2D0
TCMT141 CA5A Carbonic anhydrase VA Lyase P35218
TCMT142 CA4 Carbonic anhydrase IV Lyase P22748
TCMT143 CA3 Carbonic anhydrase III Lyase P07451
TCMT150 RORC Nuclear receptor ROR-gamma Nuclear receptor P51449
TCMT156 CYP19A1 Cytochrome P450 19A1 Oxidoreductase P11511
TCMT160 HTR7 Serotonin 7 (5-HT7) receptor GPCR P34969
TCMT162 UGT1A1 UDP-glucuronosyltransferase 1-1 Transferase P22309
TCMT164 PTGS1 Cyclooxygenase-1 Oxidoreductase P23219
TCMT17 POLB DNA polymerase beta Transferase P06746
TCMT171 PTPN6 Protein-tyrosine phosphatase 1C Hydrolase P29350
TCMT174 HSD11B1 11-beta-hydroxysteroid dehydrogenase 1 Oxidoreductase P28845
TCMT176 SOAT1 Acyl coenzyme A:cholesterol acyltransferase 1 Transferase P35610
TCMT18 GAA Lysosomal alpha-glucosidase Hydrolase P10253
TCMT189 DUSP3 Dual specificity protein phosphatase 3 Hydrolase P51452
TCMT190 PTPN2 T-cell protein-tyrosine phosphatase Hydrolase P17706
TCMT2 MAPT Microtubule-associated protein tau Unclassified P10636
TCMT215 CYP1A1 Cytochrome P450 1A1 Oxidoreductase P04798
TCMT219 CYP1A2 Cytochrome P450 1A2 Oxidoreductase P05177
TCMT223 AKR1B1 Aldose reductase Oxidoreductase P15121
TCMT225 CA13 Carbonic anhydrase XIII Lyase Q8N1Q1
TCMT239 PIM1 Serine/threonine-protein kinase PIM1 Kinase P11309
TCMT240 AMY1A Salivary alpha-amylase Unclassified P04745
TCMT248 CXCL8 Interleukin-8 Unclassified P10145
TCMT249 CDK6 Cyclin-dependent kinase 6 Kinase Q00534
TCMT257 CYP1B1 Cytochrome P450 1B1 Oxidoreductase Q16678
TCMT260 FLT3 Tyrosine-protein kinase receptor FLT3 Kinase P36888
TCMT261 DAPK1 Death-associated protein kinase 1 Kinase P53355
TCMT265 GSK3B Glycogen synthase kinase-3 beta Kinase P49841
TCMT273 NR1H4 Bile acid receptor FXR Nuclear receptor Q96RI1
TCMT280 AKR1B10 Aldo-keto reductase family 1 member B10 Oxidoreductase O60218
TCMT281 DPP4 Dipeptidyl peptidase IV Unclassified P27487
TCMT295 MMP1 Matrix metalloproteinase-1 Hydrolase P03956
TCMT297 FABP4 Fatty acid binding protein adipocyte Unclassified P15090
TCMT298 FABP3 Fatty acid binding protein muscle Hydrolase P05413
TCMT3 ALOX15 Arachidonate 15-lipoxygenase Oxidoreductase P16050
TCMT30 PTGS2 Cyclooxygenase-2 Oxidoreductase P35354
TCMT306 MMP2 Matrix metalloproteinase-2 Hydrolase P08253
TCMT307 KCNH2 HERG Ion channel Q12809
TCMT31 CYP2C19 Cytochrome P450 2C19 Oxidoreductase P33261
TCMT320 MMP3 Matrix metalloproteinase 3 Hydrolase P08254
TCMT321 MMP9 Matrix metalloproteinase 9 Hydrolase P14780
TCMT322 MMP13 Matrix metalloproteinase 13 Hydrolase P45452
TCMT33 CYP3A4 Cytochrome P450 3A4 Oxidoreductase P08684
TCMT331 PLG Plasminogen Unclassified P00747
TCMT34 CYP2D6 Cytochrome P450 2D6 Oxidoreductase P10635
TCMT41 IDH1 Isocitrate dehydrogenase [NADP] cytoplasmic Oxidoreductase O75874
TCMT42 KMT2A Histone-lysine N-methyltransferase MLL Transferase Q03164
TCMT423 EGFR Epidermal growth factor receptor erbB1 Kinase P00533
TCMT44 GLO1 Glyoxalase I Lyase Q04760
TCMT45 APP Beta amyloid A4 protein Unclassified P05067
TCMT46 F3 Coagulation factor III Unclassified P13726
TCMT47 BCL2 Apoptosis regulator Bcl-2 Ion channel P10415
TCMT508 SYK Tyrosine-protein kinase SYK Kinase P43405
TCMT558 TOP2A DNA topoisomerase II alpha Isomerase P11388
TCMT59 BCL2L1 Apoptosis regulator Bcl-X Ion channel Q07817
TCMT592 XDH Xanthine dehydrogenase Oxidoreductase P47989
TCMT598 TOP1 DNA topoisomerase I Isomerase P11387
TCMT6 NFKB1 Nuclear factor NF-kappa-B p105 subunit Transcription factor P19838
TCMT60 FASN Fatty acid synthase Unclassified P49327
TCMT63 PPARA Peroxisome proliferator-activated receptor alpha Nuclear receptor Q07869
TCMT64 PPARD Peroxisome proliferator-activated receptor delta Nuclear receptor Q03181
TCMT640 CTSD Cathepsin D Unclassified P07339
TCMT67 PPARG Peroxisome proliferator-activated receptor gamma Nuclear receptor P37231
TCMT69 THRB Thyroid hormone receptor beta-1 Nuclear receptor P10828
TCMT734 MMP12 Matrix metalloproteinase 12 Hydrolase P39900
TCMT739 GPR35 G-protein coupled receptor 35 GPCR Q9HC97
TCMT8 KDM4E Lysine-specific demethylase 4D-like Oxidoreductase B2RXH2
TCMT80 MAPK1 MAP kinase ERK2 Kinase P28482
TCMT808 FABP5 Fatty acid binding protein epidermal Unclassified Q01469
TCMT809 FABP2 Fatty acid binding protein intestinal Unclassified P12104
TCMT81 ALOX12 Arachidonate 12-lipoxygenase Oxidoreductase P18054
TCMT810 TLR2 Toll-like receptor 2 Unclassified O60603
TCMT82 ESR1 Estrogen receptor alpha Nuclear receptor P03372
TCMT83 CD38 Lymphocyte differentiation antigen CD38 Unclassified P28907
TCMT87 CYP2C9 Cytochrome P450 2C9 Oxidoreductase P11712


Targeted Pathogenic Microbes by the Ingredient of Component

Target ID Target Name
TCMT1090 Human immunodeficiency virus type 1 integrase
TCMT1092 Fatty acid synthase
TCMT1093 Enoyl-acyl-carrier protein reductase
TCMT1094 3-oxoacyl-acyl-carrier protein reductase
TCMT1099 Neuraminidase
TCMT1104 Sortase
TCMT1107 Protease
TCMT1121 Sialidase
TCMT1181 Mycobacterium tuberculosis H37Ra
TCMT1189 Pseudomonas fluorescens
TCMT1212 Verticillium dahliae
TCMT1213 Neisseria gonorrhoeae
TCMT1218 Staphylococcus aureus
TCMT1223 Staphylococcus epidermidis
TCMT1226 Klebsiella pneumoniae
TCMT1229 Enterococcus faecalis
TCMT1231 Human herpesvirus 1 strain KOS
TCMT1232 Pseudomonas aeruginosa
TCMT1246 Escherichia coli
TCMT1251 Candida albicans
TCMT1253 Penicillium chrysogenum
TCMT1255 Human immunodeficiency virus 1
TCMT1361 Neisseria meningitidis
TCMT1382 Plasmodium falciparum (isolate K1 / Thailand)
TCMT1438 Plasmodium falciparum
TCMT1442 Leishmania donovani
TCMT1443 Leishmania amazonensis
TCMT1449 Influenza A virus
TCMT1454 Bacillus subtilis
TCMT1455 Mycobacterium tuberculosis H37Rv
TCMT1458 Filobasidiella neoformans
TCMT1462 Streptococcus mutans
TCMT1463 Mycobacterium tuberculosis
TCMT1465 Entamoeba histolytica

Ingredient Structrues

Ingredient ID: TCMC995
Formula: C35H60O6

Ingredient ID: TCMC943
Formula: C30H48O4

Ingredient ID: TCMC920
Formula: C17H14O6

Ingredient ID: TCMC804
Formula: C30H48O3

Ingredient ID: TCMC759
Formula: C22H44O2

Ingredient ID: TCMC7214
Formula: C20H30O3

Ingredient ID: TCMC667
Formula: C30H50O

Ingredient ID: TCMC6649
Formula: C24H38O5

Ingredient ID: TCMC6511
Formula: C22H34O5

Ingredient ID: TCMC6254
Formula: C22H32O4

Ingredient ID: TCMC6253
Formula: C22H34O4

Ingredient ID: TCMC6070
Formula: C20H30O

Ingredient ID: TCMC5707
Formula: C21H32O4

Ingredient ID: TCMC5631
Formula: C19H30O2

Ingredient ID: TCMC5292
Formula: C22H34O5

Ingredient ID: TCMC5239
Formula: C22H34O4

Ingredient ID: TCMC4294
Formula: C18H16O8

Ingredient ID: TCMC4098
Formula: C20H32O3

Ingredient ID: TCMC3966
Formula: C29H50O

Ingredient ID: TCMC3901
Formula: C10H18O

Ingredient ID: TCMC3326
Formula: C28H48O2

Ingredient ID: TCMC304
Formula: C10H18O

Ingredient ID: TCMC2830
Formula: C7H6O3

Ingredient ID: TCMC2815
Formula: C15H24

Ingredient ID: TCMC2541
Formula: C10H18O

Ingredient ID: TCMC2539
Formula: C10H16

Ingredient ID: TCMC2491
Formula: C3H6O2

Ingredient ID: TCMC2484
Formula: C10H18O

Ingredient ID: TCMC2481
Formula: C20H20O8

Ingredient ID: TCMC2460
Formula: C23H28O12

Ingredient ID: TCMC2396
Formula: C19H18O8

Ingredient ID: TCMC2315
Formula: C30H48O3

Ingredient ID: TCMC2233
Formula: C21H20O10

Ingredient ID: TCMC2223
Formula: C8H8O3

Ingredient ID: TCMC2222
Formula: C8H8O4

Ingredient ID: TCMC2216
Formula: C30H48O3

Ingredient ID: TCMC2129
Formula: C30H50O

Ingredient ID: TCMC2105
Formula: C18H36O2

Ingredient ID: TCMC2006
Formula: C20H30O

Ingredient ID: TCMC1871
Formula: C6H6O

Ingredient ID: TCMC1839
Formula: C7H6O3

Ingredient ID: TCMC1834
Formula: C8H8O3

Ingredient ID: TCMC1832
Formula: C16H30O2

Ingredient ID: TCMC1830
Formula: C16H32O2

Ingredient ID: TCMC1788
Formula: C18H34O2

Ingredient ID: TCMC1611
Formula: C14H28O2

Ingredient ID: TCMC1608
Formula: C10H16

Ingredient ID: TCMC1516
Formula: C15H10O6