Component: Acanthopanax gracilistylus 五加皮


Description of the Component

Component ID
 TCMH2185
Latin Name
 Acanthopanax gracilistylus
English Name
 Slenderstyle acanthopanax root-bark
Chinese Pinyin Name
 Wu Jia Pi
中文名
 五加皮
TCM Properties
 Warm,Pungent,Bitter
TCM Meridians
 Liver,Kidney
Therapeutic Class English
 For dispelling wind-dampness
Therapeutic Class Chinese
 祛风湿
Functions
 relieve rheumatic conditions, and tonify the liver and the kindney, and strengthen the tendons and bones
Toxicity
 NA
Geo-authentic habitats (道地产区)
 Hubei Province
Reference
 Chinese Pharmacopoeia (2015)
Barcode ID
Barcode Source

TCM Prescriptions with the Component

Prescription ID Prescription English Name Prescription Chinese Name
TCMF2963 An Yang Hu Gu Yao Wine 安阳虎骨药酒
TCMFx3114 Ban Feng He Yao Wine 半枫荷药酒
TCMFx3509 Bao Gu Mu Gua Wine 豹骨木瓜酒
TCMF3501 Bao Gu Wine 豹骨酒
TCMF3516 Bao Gu Zhui Feng Ointment 豹骨追风膏
TCMF6024 Chang Chun Yao Wine 长春药酒
TCMFx2596 Crab Bone-Joining Powder 螃蟹接骨散
TCMFx3786 Da Li Yao Wine 大力药酒
TCMF3914 Dan Tian Jiang Zhi Pills 丹田降脂丸
TCMFx3348 Die Da Feng Shi Wine 跌打风湿酒
TCMF3799 Du Zhong Yao Wine 杜仲药酒
TCMFx3337 Feng Shi An Tai Tablets 风湿安泰片
TCMF3462 Feng Shi Ning Yao Wine 风湿宁药酒
TCMFx3150 Fu Fang Xia Tian Wu Tablets 复方夏天无片
TCMF3669 Guan Jie Feng Tong Pills 关节风痛丸
TCMFx3678 Guan Jie Jie Tong Ointment 关节解痛膏
TCMFx4695 Hu Gu Zhui Feng Wine 虎骨追风酒
TCMF4232 Hui Chun Wine 回春酒
TCMFx4317 Huo Luo Jian Shen Oral Liquid 活络健身液
TCMFx4611 Jie Gu Ling Tie Ointment 接骨灵贴膏
TCMFx4292 Jin Gu Ning Ointment 筋骨宁膏
TCMFx4069 Jin Qian Bai Hua She Yao Wine 金钱白花蛇药酒
TCMF4452 Jing Zhi Wu Jia Pi Wine 精制五加皮酒
TCMF4750 Lu Gu Xue Lian Wine 鹿骨雪莲酒
TCMFx4869 Luo Fu Shan Feng Shi Gao Yao 罗浮山风湿膏药
TCMF4590 Mu Gua Wine 木瓜酒
TCMFx1531 Oral Liquid of Ginseng and Acanthopanax
TCMFx4456 Pan Long Qi Tablets 盘龙七片
TCMFx4463 Pan Long Qi Yao Wine 盘龙七药酒
TCMFx4874 Qi She Zhui Feng Wine 蕲蛇追风酒
TCMF4962 Qiang Shen Wine 强身酒
TCMF4977 Qiang Shen Zhuang Gu Wine 强身壮骨酒
TCMFx5109 Qu Feng Chu Shi Yao Wine 祛风除湿药酒
TCMF5093 Qu Feng Oral Liquid 驱风液
TCMF5062 Qu Feng She Wine 驱风蛇酒
TCMFx5121 San Qi Yao Wine 三七药酒
TCMFx5753 Shang Shi Zhen Tong Ointment 伤湿镇痛膏
TCMFx5886 Shao Lin Zheng Gu Jing 少林正骨精
TCMF7029 Shen Lu Fu Zheng Capsules 参鹿扶正胶囊
TCMFx5358 Shen Nong Yao Wine 神农药酒
TCMF3605 Shen Rong Mu Gua Yao Wine 参茸木瓜药酒
TCMFx5160 Sun Shang Zhi Tong Ointment 损伤止痛膏
TCMFx2237 Tablet for Relieving Rigidity of Muscles and Promoting Blood Circulation 舒筋活血片
TCMFx5535 Tian Qi Die Da Feng Shi Ruan Ointment 田七跌打风湿软膏
TCMF5385 Wan Ying Bao Zhen Ointment 万应宝珍膏
TCMF5461 Wu Jia Pi Wine 五加皮酒
TCMFx7308 Wu Pi Decoction 五皮饮
TCMFx6037 Xiao Feng Powder 消疯散
TCMFx6496 Xiao Zhong Zhi Tong Ding 消肿止痛酊
TCMFx1021 Xiao Zhong Zhi Tong Tincture 消肿止痛酊
TCMF6178 Yao Zhui Bi Tong Pills 腰椎痹痛丸
TCMFx6833 Zhang Zhou Shen Qu 漳州神曲
TCMFx6317 Zheng Gu Decoction 正骨水
TCMFx6310 Zheng Gu Ointment 正骨膏
TCMFx6635 Zhui Feng Qiang Shen Wine 追风强肾酒

Targeted Human Proteins by the Ingredient of Component

Target ID Gene Symbol Target Name Target Class Uniprot ID
TCMT1 EHMT2 Histone-lysine N-methyltransferase, H3 lysine-9 specific 3 Transferase Q96KQ7
TCMT101 PTPN1 Protein-tyrosine phosphatase 1B Hydrolase P18031
TCMT126 TERT Telomerase reverse transcriptase Transferase O14746
TCMT156 CYP19A1 Cytochrome P450 19A1 Oxidoreductase P11511
TCMT164 PTGS1 Cyclooxygenase-1 Oxidoreductase P23219
TCMT174 HSD11B1 11-beta-hydroxysteroid dehydrogenase 1 Oxidoreductase P28845
TCMT2 MAPT Microtubule-associated protein tau Unclassified P10636
TCMT3 ALOX15 Arachidonate 15-lipoxygenase Oxidoreductase P16050
TCMT30 PTGS2 Cyclooxygenase-2 Oxidoreductase P35354
TCMT33 CYP3A4 Cytochrome P450 3A4 Oxidoreductase P08684
TCMT341 NR1I2 Pregnane X receptor Nuclear receptor O75469
TCMT41 IDH1 Isocitrate dehydrogenase [NADP] cytoplasmic Oxidoreductase O75874
TCMT46 F3 Coagulation factor III Unclassified P13726
TCMT6 NFKB1 Nuclear factor NF-kappa-B p105 subunit Transcription factor P19838
TCMT63 PPARA Peroxisome proliferator-activated receptor alpha Nuclear receptor Q07869
TCMT64 PPARD Peroxisome proliferator-activated receptor delta Nuclear receptor Q03181
TCMT67 PPARG Peroxisome proliferator-activated receptor gamma Nuclear receptor P37231
TCMT8 KDM4E Lysine-specific demethylase 4D-like Oxidoreductase B2RXH2


Targeted Pathogenic Microbes by the Ingredient of Component

Target ID Target Name
TCMT1104 Sortase
TCMT1218 Staphylococcus aureus

Ingredient Structrues

Ingredient ID: TCMC995
Formula: C35H60O6

Ingredient ID: TCMC6821
Formula: C99H194O6

Ingredient ID: TCMC4695
Formula: C20H36O2

Ingredient ID: TCMC2105
Formula: C18H36O2

Ingredient ID: TCMC2067
Formula: C7H6O3

Ingredient ID: TCMC1496
Formula: C18H30O2

Ingredient ID: TCMC1436
Formula: C20H30O2

Properties

Ingredient ID Formulae Name MW AlogP MlogP XlogP # HBA # HBD PSA # Rotatable Bond # Ring # Heacy Atom Lipinski RO5 Violation
TCMC995 C35H60O6 Daucosterol 576.44 -0.4469 4.65 10.487 6 4 99.38 19 5 41 1
TCMC1436 C20H30O2 Kaurenoic Acid 302.22 1.3222 3.44 6.629 2 1 37.3 4 4 22 1
TCMC1496 C18H30O2 Linolenic Acid 278.22 -0.0979 3.22 7.538 2 1 37.3 15 0 20 2
TCMC2067 C7H6O3 Sesamol 138.03 -0.763 1.9 0.872 0 1 38.69 1 2 10 0
TCMC2105 C18H36O2 Stearic Acid 284.27 -4.4737 3.22 8.708 2 1 37.3 18 0 20 2
TCMC4695 C20H36O2 Linoleyl Acetate 308.2715304 -1.1011 3.44 8.714 2 0 26.3 16 0 22 2
TCMC6821 C99H194O6 Stearin 1479.487544 -25.0982 11.69 50.602 6 0 78.9 98 0 105 2

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1. General Information of the Component  
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3. Putative Targets  
4. Activity & References for Filtering Putative Targets  
5. Ingredient Data & Chemical Structure Information (Properties, InChI, InChIkey, SMILES, etc.)