TCM Prescription: Wu Pi Decoction



Prescription Description
Prescription IDTCMFx7308
Pinyin NameWu Pi Yin
Chinese Name五皮饮
English NameWu Pi Decoction
Function Description水病肿满, 上气喘急, 小便不利
IndicationsNone
Disease ICD-11 Category
Human Tissues Associated with IndicationKidney
ReferenceTaiwan Herbal Pharmacopeia 2nd Edition English Version
Reference Book/linkhttps://www.mohw.gov.tw/cp-3690-39025-2.html
Prescription Components
Component ID Latin Name Chinese Name Component Quantity Barcode
TCMH2185 Acanthopanax gracilistylus 五加皮 TCMH2185
TCMH449 Cortex lycii radicis 地骨皮 TCMH449
TCMH1065 Cortex zingiberis 姜皮 TCMH1065
TCMH357 Pericarpium arecae 大腹皮 TCMH357
TCMH607 Exodermis poria 茯苓皮 TCMH607
Reference: Taiwan Herbal Pharmacopeia 2nd Edition English Version

Targeted Human Proteins by the Ingredients of Prescription

Target ID Gene Symbol Target Name Target Class Uniprot ID
TCMT133 CA1 Carbonic anhydrase I Lyase P00915
TCMT134 CA2 Carbonic anhydrase II Lyase P00918
TCMT223 AKR1B1 Aldose reductase Oxidoreductase P15121
TCMT292 CHRM1 Muscarinic acetylcholine receptor M1 GPCR P11229
TCMT293 CHRM2 Muscarinic acetylcholine receptor M2 GPCR P08172
TCMT327 TRPV1 Vanilloid receptor Ion channel Q8NER1
TCMT551 CHRM4 Muscarinic acetylcholine receptor M4 GPCR P08173
TCMT810 TLR2 Toll-like receptor 2 Unclassified O60603
TCMT87 CYP2C9 Cytochrome P450 2C9 Oxidoreductase P11712


Targeted Pathogenic Microbes by the Ingredients of Prescription

Target ID Target Name
TCMT1212 Verticillium dahliae
TCMT1218 Staphylococcus aureus
TCMT1232 Pseudomonas aeruginosa
TCMT1246 Escherichia coli
TCMT1253 Penicillium chrysogenum
TCMT1438 Plasmodium falciparum
TCMT1448 Enterobacter aerogenes
TCMT1454 Bacillus subtilis
TCMT1462 Streptococcus mutans
TCMT1463 Mycobacterium tuberculosis

Gene Ontology Associated to Targeted Human Proteins

GO Term GO Name Enriched Genes Log10 Adjusted P-value


KEGG Pathways Associated to Targeted Human Proteins

KEGG Pathway ID Enriched Genes Log10 Adjusted P-value


Target Exprsssion in Healthy Human Tissues (protein & mRNA level)

Protein expression data was from the "Human Proteome Map" dataset
mRNA expression data was from the "GTEx" dataset



Average Target Expression (Fold Change) in Multiple Disease Conditions

Fold Change with Corresponding Normal Samples
Click each cell within the heatmap to access gene expression of individual patient samples
Data Section
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1. General Information of Prescription  
2. Putative Targets  
3. Activity & References for Filtering Putative Targets  
4. GO & Pathway