Component: Fructus kochiae 地肤子


Description of the Component

Component ID
 TCMH448
Latin Name
 Fructus kochiae
English Name
 fruit of belvedere
Chinese Pinyin Name
 Di Fu Zi
中文名
 地肤子
TCM Properties
 Cold,Bitter
TCM Meridians
 Bladder
Therapeutic Class English
 For promoting diuresis and penetrating dampness
Therapeutic Class Chinese
 利水渗湿
Functions
 remove damp-heat, dispel zvind, and relieve itching
Toxicity
 NA
Geo-authentic habitats (道地产区)
 Hebei Province,Beijing,Tianjin
Reference
 Chinese Pharmacopoeia (2015)
Barcode ID
Barcode Source

TCM Prescriptions with the Component

Prescription ID Prescription English Name Prescription Chinese Name
TCMF2434 Added Flavor DFZ Heat Clearing Decoction 加味地肤子汤
TCMFx3297 Chu Zhi Sheng Fa Tablets 除脂生发片
TCMFx7035 Chuan Bai Zhi Yang Xi Ji 川百止痒洗剂
TCMFx1943 Combined Chan Yi Nephritis Decoction
TCMF3375 Feng Shi Gao Yao 风湿膏药
TCMFx6888 Fu Fang Huang Song Xi Oral Liquid 复方黄松洗液
TCMFx6872 Fu Yang Granules 肤痒颗粒
TCMFx3659 Fu Yang Infusion 肤痒冲剂
TCMF7082 Jie Er Yin Pao Teng Tablets 洁尔阴泡腾片
TCMF6977 Jie Er Yin Xi Oral Liquid 洁尔阴洗液
TCMF7137 Jin Chan Zhi Yang Granules 金蝉止痒颗粒
TCMF6973 Jin Zhi Jie Yin Han Shu Oral Liquid 金栀洁龈含漱液
TCMF7108 Jing Fu Zhi Yang Granules 荆肤止痒颗粒
TCMF4529 Ming Mu Yang Gan Pills 明目羊肝丸
TCMFx4511 Pi Fu Bing Xue Du Pills 皮肤病血毒丸
TCMFx7218 Shuang Zi Shen Xi Oral Liquid 双子参洗液
TCMF2362 Three Ginseng and Two White Colon Disease Decoction 三参二白汤
TCMFx5293 Wai Yong Wu Di Ointment 外用无敌膏
TCMFx2162 Wu Decoction
TCMFx6336 Xuan Ling Yao Decoction 癣灵药水
TCMFx108 Xuan Ning Liniment 癣宁搽剂
TCMF6321 Yu Lin Bing Tablets 鱼鳞病片

Targeted Human Proteins by the Ingredient of Component

Target ID Gene Symbol Target Name Target Class Uniprot ID
TCMT1 EHMT2 Histone-lysine N-methyltransferase, H3 lysine-9 specific 3 Transferase Q96KQ7
TCMT125 GBA Beta-glucocerebrosidase Hydrolase P04062
TCMT126 TERT Telomerase reverse transcriptase Transferase O14746
TCMT156 CYP19A1 Cytochrome P450 19A1 Oxidoreductase P11511
TCMT164 PTGS1 Cyclooxygenase-1 Oxidoreductase P23219
TCMT17 POLB DNA polymerase beta Transferase P06746
TCMT2 MAPT Microtubule-associated protein tau Unclassified P10636
TCMT239 PIM1 Serine/threonine-protein kinase PIM1 Kinase P11309
TCMT3 ALOX15 Arachidonate 15-lipoxygenase Oxidoreductase P16050
TCMT30 PTGS2 Cyclooxygenase-2 Oxidoreductase P35354
TCMT33 CYP3A4 Cytochrome P450 3A4 Oxidoreductase P08684
TCMT341 NR1I2 Pregnane X receptor Nuclear receptor O75469
TCMT46 F3 Coagulation factor III Unclassified P13726
TCMT63 PPARA Peroxisome proliferator-activated receptor alpha Nuclear receptor Q07869
TCMT64 PPARD Peroxisome proliferator-activated receptor delta Nuclear receptor Q03181
TCMT67 PPARG Peroxisome proliferator-activated receptor gamma Nuclear receptor P37231
TCMT8 KDM4E Lysine-specific demethylase 4D-like Oxidoreductase B2RXH2


Targeted Pathogenic Microbes by the Ingredient of Component

Target ID Target Name
TCMT1099 Neuraminidase
TCMT1454 Bacillus subtilis
TCMT1455 Mycobacterium tuberculosis H37Rv

Ingredient Structrues

Ingredient ID: TCMC1496
Formula: C18H30O2

Ingredient ID: TCMC1329
Formula: C16H12O6

Properties

Ingredient ID Formulae Name MW AlogP MlogP XlogP # HBA # HBD PSA # Rotatable Bond # Ring # Heacy Atom Lipinski RO5 Violation
TCMC1329 C16H12O6 Hispidulin 300.06 -1.9363 2.56 1.123 1 3 96.22 6 3 22 0
TCMC1496 C18H30O2 Linolenic Acid 278.22 -0.0979 3.22 7.538 2 1 37.3 15 0 20 2

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1. General Information of the Component  
2. TCM Prescriptions with the Component  
3. Putative Targets  
4. Activity & References for Filtering Putative Targets  
5. Ingredient Data & Chemical Structure Information (Properties, InChI, InChIkey, SMILES, etc.)